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Illumina Body Map 2, young vs old

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Results for DDIT3

Z-value: 1.40

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Transcription factors associated with DDIT3

Gene Symbol Gene ID Gene Info
DDIT3
ENSG00000175197.6 DNA damage inducible transcript 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DDIT3hg19_v2_chr12_-_57914275_57914304-0.251.6e-01Click!

Activity profile of DDIT3 motif

Sorted Z-values of DDIT3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_92681033 4.37 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr2_-_179672142 4.13 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN
titin
chr10_-_116444371 2.30 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr15_+_85923797 1.71 ENST00000559362.1
AKAP13
A kinase (PRKA) anchor protein 13
chr14_+_32798547 1.70 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr14_+_32798462 1.61 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr22_+_31518938 1.60 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr7_+_80255472 1.55 ENST00000428497.1
CD36
CD36 molecule (thrombospondin receptor)
chr2_+_63816126 1.46 ENST00000454035.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr5_-_178017355 1.44 ENST00000390654.3
COL23A1
collagen, type XXIII, alpha 1
chr10_-_17659357 1.43 ENST00000326961.6
ENST00000361271.3
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr15_+_85923856 1.35 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
AKAP13
A kinase (PRKA) anchor protein 13
chr2_+_63816269 1.33 ENST00000432309.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr3_+_157154578 1.32 ENST00000295927.3
PTX3
pentraxin 3, long
chr2_-_40680578 1.29 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr10_-_17659234 1.25 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr17_+_4855053 1.19 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr2_+_63816295 1.16 ENST00000539945.1
ENST00000544381.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr2_+_7118755 1.14 ENST00000433456.1
RNF144A
ring finger protein 144A
chr2_+_63816087 1.12 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr6_+_144606817 1.08 ENST00000433557.1
UTRN
utrophin
chr1_+_150954493 1.04 ENST00000368947.4
ANXA9
annexin A9
chr12_+_32638897 1.03 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_+_111770294 1.01 ENST00000474304.2
CHI3L2
chitinase 3-like 2
chr14_+_21387491 0.96 ENST00000258817.2
RP11-84C10.2
RP11-84C10.2
chr1_+_111770278 0.96 ENST00000369748.4
CHI3L2
chitinase 3-like 2
chr15_-_64126084 0.94 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr1_+_111770232 0.92 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chr14_+_64565442 0.91 ENST00000553308.1
SYNE2
spectrin repeat containing, nuclear envelope 2
chr15_-_83837983 0.79 ENST00000562702.1
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr2_+_223289208 0.78 ENST00000321276.7
SGPP2
sphingosine-1-phosphate phosphatase 2
chr7_-_44530479 0.78 ENST00000355451.7
NUDCD3
NudC domain containing 3
chr4_+_6784358 0.77 ENST00000508423.1
KIAA0232
KIAA0232
chr10_+_60028818 0.77 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr18_-_55288973 0.75 ENST00000423481.2
ENST00000587194.1
ENST00000591599.1
ENST00000588661.1
NARS
asparaginyl-tRNA synthetase
chr5_+_112074029 0.74 ENST00000512211.2
APC
adenomatous polyposis coli
chr4_+_6784401 0.73 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr1_+_169079823 0.71 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_-_63815860 0.71 ENST00000272321.7
ENST00000431065.1
WDPCP
WD repeat containing planar cell polarity effector
chr2_-_183106641 0.70 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr6_-_86353510 0.69 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chrX_+_149867681 0.67 ENST00000438018.1
ENST00000436701.1
MTMR1
myotubularin related protein 1
chr1_+_174844645 0.66 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr9_+_112542591 0.65 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
PALM2
PALM2-AKAP2
AKAP2
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr19_-_35992780 0.64 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr14_+_102276132 0.63 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr5_-_131630931 0.60 ENST00000431054.1
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr5_+_154135029 0.57 ENST00000518297.1
LARP1
La ribonucleoprotein domain family, member 1
chr1_+_90308981 0.56 ENST00000527156.1
LRRC8D
leucine rich repeat containing 8 family, member D
chr17_+_30594823 0.56 ENST00000536287.1
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr8_+_26435915 0.56 ENST00000523027.1
DPYSL2
dihydropyrimidinase-like 2
chr12_-_25101920 0.55 ENST00000539780.1
ENST00000546285.1
ENST00000342945.5
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr8_-_93029520 0.54 ENST00000521553.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr20_+_54987305 0.53 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr3_-_9595480 0.52 ENST00000287585.6
LHFPL4
lipoma HMGIC fusion partner-like 4
chr11_+_34073269 0.51 ENST00000389645.3
CAPRIN1
cell cycle associated protein 1
chr22_-_27456361 0.50 ENST00000453934.1
CTA-992D9.6
CTA-992D9.6
chr13_-_24007815 0.49 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr1_+_149804218 0.46 ENST00000610125.1
HIST2H4A
histone cluster 2, H4a
chr12_-_12491608 0.46 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr20_+_54987168 0.45 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr9_-_95055956 0.45 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr10_+_102756800 0.43 ENST00000370223.3
LZTS2
leucine zipper, putative tumor suppressor 2
chr6_+_80341000 0.41 ENST00000369838.4
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr12_-_53074182 0.41 ENST00000252244.3
KRT1
keratin 1
chr4_+_141178440 0.41 ENST00000394205.3
SCOC
short coiled-coil protein
chr16_-_18908196 0.40 ENST00000565324.1
ENST00000561947.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr3_+_38017264 0.40 ENST00000436654.1
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr14_+_102276192 0.39 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr12_-_52867569 0.38 ENST00000252250.6
KRT6C
keratin 6C
chr19_+_10736183 0.37 ENST00000590857.1
ENST00000588688.1
ENST00000586078.1
SLC44A2
solute carrier family 44 (choline transporter), member 2
chr9_+_112542572 0.37 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr2_+_68872954 0.36 ENST00000394342.2
PROKR1
prokineticin receptor 1
chr5_+_118812237 0.35 ENST00000513628.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr15_+_77861183 0.34 ENST00000560590.1
ENST00000561123.1
RP11-307C19.2
RP11-307C19.2
chr11_-_10315741 0.33 ENST00000256190.8
SBF2
SET binding factor 2
chr15_+_59730348 0.33 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr2_-_63815628 0.33 ENST00000409562.3
WDPCP
WD repeat containing planar cell polarity effector
chr9_+_70971815 0.33 ENST00000396392.1
ENST00000396396.1
PGM5
phosphoglucomutase 5
chr12_-_7899935 0.33 ENST00000543765.1
CLEC4C
C-type lectin domain family 4, member C
chr1_-_149832704 0.33 ENST00000392933.1
ENST00000369157.2
ENST00000392932.4
HIST2H4B
histone cluster 2, H4b
chr22_+_17956618 0.32 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr1_+_152815327 0.32 ENST00000431011.2
LCE6A
late cornified envelope 6A
chr14_+_21387508 0.32 ENST00000555624.1
RP11-84C10.2
RP11-84C10.2
chr17_-_47925379 0.31 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4
tachykinin 4 (hemokinin)
chr8_-_18744528 0.31 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr6_-_157744531 0.31 ENST00000400788.4
ENST00000367144.4
TMEM242
transmembrane protein 242
chr12_-_95774672 0.31 ENST00000549961.1
RP11-167N24.6
Uncharacterized protein
chr8_-_21669826 0.31 ENST00000517328.1
GFRA2
GDNF family receptor alpha 2
chr1_-_152196669 0.31 ENST00000368801.2
HRNR
hornerin
chr5_+_145583107 0.30 ENST00000506502.1
RBM27
RNA binding motif protein 27
chr21_-_46334186 0.30 ENST00000522931.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_+_72143988 0.30 ENST00000506351.2
TNPO1
transportin 1
chr4_+_157997209 0.30 ENST00000264428.4
GLRB
glycine receptor, beta
chr12_-_25102252 0.29 ENST00000261192.7
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr10_+_86004802 0.29 ENST00000359452.4
ENST00000358110.5
ENST00000372092.3
RGR
retinal G protein coupled receptor
chr7_-_99006443 0.29 ENST00000350498.3
PDAP1
PDGFA associated protein 1
chr10_-_103874692 0.29 ENST00000361198.5
LDB1
LIM domain binding 1
chr9_+_110045418 0.29 ENST00000419616.1
RAD23B
RAD23 homolog B (S. cerevisiae)
chr5_+_118812294 0.29 ENST00000509514.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr6_-_48036363 0.28 ENST00000543600.1
ENST00000398738.2
ENST00000339488.4
PTCHD4
patched domain containing 4
chr17_-_2117600 0.27 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr9_-_95056010 0.27 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr17_+_4336955 0.25 ENST00000355530.2
SPNS3
spinster homolog 3 (Drosophila)
chr3_+_130569429 0.24 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr1_-_44820880 0.24 ENST00000372257.2
ENST00000457571.1
ENST00000452396.1
ERI3
ERI1 exoribonuclease family member 3
chr8_-_82645082 0.23 ENST00000523361.1
ZFAND1
zinc finger, AN1-type domain 1
chr20_-_60294804 0.23 ENST00000317652.1
RP11-429E11.3
Uncharacterized protein
chr12_+_64798826 0.22 ENST00000540203.1
XPOT
exportin, tRNA
chr1_-_161277210 0.21 ENST00000491222.2
MPZ
myelin protein zero
chr4_+_157997273 0.21 ENST00000541722.1
ENST00000512619.1
GLRB
glycine receptor, beta
chr12_-_63328817 0.21 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr14_+_22265444 0.21 ENST00000390430.2
TRAV8-1
T cell receptor alpha variable 8-1
chr7_-_130597935 0.20 ENST00000447307.1
ENST00000418546.1
MIR29B1
microRNA 29a
chr2_-_159313214 0.20 ENST00000409889.1
ENST00000283233.5
ENST00000536771.1
CCDC148
coiled-coil domain containing 148
chr11_+_20044096 0.19 ENST00000533917.1
NAV2
neuron navigator 2
chrX_-_40506766 0.19 ENST00000378421.1
ENST00000440784.2
ENST00000327877.5
ENST00000378426.1
ENST00000378418.2
CXorf38
chromosome X open reading frame 38
chr19_+_1450112 0.19 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
APC2
adenomatosis polyposis coli 2
chr7_+_18329712 0.19 ENST00000433709.2
HDAC9
histone deacetylase 9
chr17_+_4337199 0.18 ENST00000333476.2
SPNS3
spinster homolog 3 (Drosophila)
chr3_+_12392971 0.18 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr11_-_33913708 0.18 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr9_-_124991124 0.18 ENST00000394319.4
ENST00000340587.3
LHX6
LIM homeobox 6
chr16_+_56970567 0.18 ENST00000563911.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr14_-_23446021 0.17 ENST00000553592.1
AJUBA
ajuba LIM protein
chr9_+_125486269 0.17 ENST00000259466.1
OR1L4
olfactory receptor, family 1, subfamily L, member 4
chr19_+_33865218 0.17 ENST00000585933.2
CEBPG
CCAAT/enhancer binding protein (C/EBP), gamma
chr1_-_20250110 0.17 ENST00000375116.3
PLA2G2E
phospholipase A2, group IIE
chr5_-_137878887 0.16 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr4_-_2935674 0.16 ENST00000514800.1
MFSD10
major facilitator superfamily domain containing 10
chr7_+_18536090 0.16 ENST00000441986.1
HDAC9
histone deacetylase 9
chr8_-_93029865 0.15 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_+_56316054 0.13 ENST00000581008.1
LPO
lactoperoxidase
chr3_+_136676707 0.13 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr11_+_62495541 0.13 ENST00000530625.1
ENST00000513247.2
TTC9C
tetratricopeptide repeat domain 9C
chr1_+_154229547 0.13 ENST00000428595.1
UBAP2L
ubiquitin associated protein 2-like
chr11_-_104972158 0.12 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr1_+_114447763 0.11 ENST00000369563.3
DCLRE1B
DNA cross-link repair 1B
chr6_+_168399772 0.11 ENST00000443060.2
KIF25
kinesin family member 25
chr1_-_114447683 0.09 ENST00000256658.4
ENST00000369564.1
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr5_+_145583156 0.09 ENST00000265271.5
RBM27
RNA binding motif protein 27
chr4_-_99578789 0.09 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr1_-_114447412 0.08 ENST00000369567.1
ENST00000369566.3
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr7_-_56101826 0.08 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr2_-_32390801 0.08 ENST00000608489.1
RP11-563N4.1
RP11-563N4.1
chr1_+_222910625 0.08 ENST00000360827.2
FAM177B
family with sequence similarity 177, member B
chr14_-_23446003 0.07 ENST00000553911.1
AJUBA
ajuba LIM protein
chr2_+_227700652 0.07 ENST00000341329.3
ENST00000392062.2
ENST00000437454.1
ENST00000443477.1
ENST00000423616.1
ENST00000448992.1
RHBDD1
rhomboid domain containing 1
chr2_-_101925055 0.06 ENST00000295317.3
RNF149
ring finger protein 149
chr14_+_22362613 0.06 ENST00000390438.2
TRAV8-4
T cell receptor alpha variable 8-4
chr7_+_44040488 0.06 ENST00000258704.3
SPDYE1
speedy/RINGO cell cycle regulator family member E1
chr9_-_107361788 0.05 ENST00000374779.2
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr12_-_7899958 0.05 ENST00000360345.3
CLEC4C
C-type lectin domain family 4, member C
chr17_-_30228678 0.05 ENST00000261708.4
UTP6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr7_+_90338547 0.04 ENST00000446790.1
CDK14
cyclin-dependent kinase 14
chr13_+_24844979 0.02 ENST00000454083.1
SPATA13
spermatogenesis associated 13
chr10_+_103986085 0.02 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr16_-_70323422 0.02 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr20_+_5987890 0.02 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr9_-_77502636 0.02 ENST00000449912.2
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr4_+_19457034 0.01 ENST00000511431.1
RP11-608O21.1
RP11-608O21.1
chr19_+_49258775 0.00 ENST00000593756.1
FGF21
fibroblast growth factor 21

Network of associatons between targets according to the STRING database.

First level regulatory network of DDIT3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.5 3.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.4 3.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 5.1 GO:0006108 malate metabolic process(GO:0006108)
0.2 1.3 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.2 0.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 0.7 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 0.7 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.2 1.0 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.2 2.9 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 4.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.8 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 1.6 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 1.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.6 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 0.5 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 0.9 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.6 GO:0072752 cellular response to rapamycin(GO:0072752)
0.1 0.6 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.7 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 1.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 1.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 2.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.3 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.3 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.8 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.4 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.4 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.3 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.5 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.8 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 2.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.2 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.8 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 0.5 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 1.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:0036457 keratohyalin granule(GO:0036457)
0.1 0.7 GO:0097452 GAIT complex(GO:0097452)
0.1 3.9 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.1 GO:0070938 contractile ring(GO:0070938)
0.1 0.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.5 GO:0070852 cell body fiber(GO:0070852)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 1.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.9 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.0 GO:0044447 axoneme part(GO:0044447)
0.0 2.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 3.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.0 4.4 GO:0001650 fibrillar center(GO:0001650)
0.0 2.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.0 5.3 GO:0043209 myelin sheath(GO:0043209)
0.0 1.3 GO:1904724 tertiary granule lumen(GO:1904724)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.3 5.1 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.3 4.1 GO:0031433 telethonin binding(GO:0031433)
0.2 3.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 1.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2 0.7 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 2.9 GO:0004568 chitinase activity(GO:0004568)
0.2 3.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.8 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 1.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.3 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.6 GO:0052658 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.6 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.5 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.4 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 1.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.0 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.8 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 2.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 3.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 5.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)