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Illumina Body Map 2, young vs old

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Results for DLX1_HOXA3_BARX2

Z-value: 0.63

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Transcription factors associated with DLX1_HOXA3_BARX2

Gene Symbol Gene ID Gene Info
ENSG00000144355.10 distal-less homeobox 1
ENSG00000105997.18 homeobox A3
ENSG00000043039.5 BARX homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BARX2hg19_v2_chr11_+_129245796_1292458350.504.0e-03Click!
DLX1hg19_v2_chr2_+_172949468_1729495220.494.1e-03Click!
HOXA3hg19_v2_chr7_-_27153454_271534690.318.9e-02Click!

Activity profile of DLX1_HOXA3_BARX2 motif

Sorted Z-values of DLX1_HOXA3_BARX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_151503077 2.04 ENST00000317605.4
mab-21-like 2 (C. elegans)
chr2_-_89161432 1.93 ENST00000390242.2
immunoglobulin kappa joining 1
chr4_-_138453606 1.61 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr17_-_38821373 1.58 ENST00000394052.3
keratin 222
chr4_+_88896819 1.57 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
secreted phosphoprotein 1
chr3_+_43020773 1.54 ENST00000488863.1
family with sequence similarity 198, member A
chr13_+_53602894 1.52 ENST00000219022.2
olfactomedin 4
chr4_+_71063641 1.43 ENST00000514097.1
odontogenic, ameloblast asssociated
chrX_-_13835147 1.40 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr3_+_2933893 1.38 ENST00000397459.2
contactin 4
chr4_-_87028478 1.36 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr15_+_69857515 1.34 ENST00000559477.1
RP11-279F6.1
chr9_-_95166976 1.32 ENST00000447356.1
osteoglycin
chr14_+_95027772 1.30 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr9_-_95166884 1.26 ENST00000375561.5
osteoglycin
chrX_-_18690210 1.26 ENST00000379984.3
retinoschisin 1
chr9_-_95166841 1.24 ENST00000262551.4
osteoglycin
chr4_-_175041663 1.23 ENST00000503140.1
RP11-148L24.1
chr15_-_37393406 1.19 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr12_-_15374343 1.19 ENST00000256953.2
ENST00000546331.1
RAS-like, estrogen-regulated, growth inhibitor
chr1_-_190446759 1.17 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr11_+_24518723 1.14 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
leucine zipper protein 2
chr15_+_58702742 1.07 ENST00000356113.6
ENST00000414170.3
lipase, hepatic
chr10_-_50970382 1.07 ENST00000419399.1
ENST00000432695.1
oxoglutarate dehydrogenase-like
chr8_+_70476088 1.06 ENST00000525999.1
sulfatase 1
chr2_+_234826016 1.06 ENST00000324695.4
ENST00000433712.2
transient receptor potential cation channel, subfamily M, member 8
chr10_-_50970322 1.04 ENST00000374103.4
oxoglutarate dehydrogenase-like
chr14_+_85994943 1.03 ENST00000553678.1
Uncharacterized protein
chr11_+_101918153 1.02 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
chromosome 11 open reading frame 70
chr4_-_138453559 0.99 ENST00000511115.1
protocadherin 18
chr16_+_82090028 0.99 ENST00000568090.1
hydroxysteroid (17-beta) dehydrogenase 2
chr2_+_228736335 0.97 ENST00000440997.1
ENST00000545118.1
dynein assembly factor with WDR repeat domains 1
chrX_-_73051037 0.97 ENST00000445814.1
X inactive specific transcript (non-protein coding)
chr1_+_81771806 0.96 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
latrophilin 2
chr4_-_176812842 0.96 ENST00000507540.1
glycoprotein M6A
chr13_+_110958124 0.94 ENST00000400163.2
collagen, type IV, alpha 2
chrX_-_110507098 0.94 ENST00000541758.1
calpain 6
chr3_+_111717511 0.93 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr4_-_186570679 0.93 ENST00000451974.1
sorbin and SH3 domain containing 2
chr12_-_22063787 0.92 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chrX_-_50386648 0.91 ENST00000460112.3
shroom family member 4
chr4_-_69536346 0.91 ENST00000338206.5
UDP glucuronosyltransferase 2 family, polypeptide B15
chr3_+_111717600 0.90 ENST00000273368.4
transgelin 3
chr12_-_23737534 0.90 ENST00000396007.2
SRY (sex determining region Y)-box 5
chr1_+_196743943 0.89 ENST00000471440.2
ENST00000391985.3
complement factor H-related 3
chr8_-_86290333 0.89 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
carbonic anhydrase I
chr3_+_28390637 0.88 ENST00000420223.1
ENST00000383768.2
zinc finger, CW type with PWWP domain 2
chr2_-_89161064 0.88 ENST00000390241.2
immunoglobulin kappa joining 2
chr3_+_111718036 0.87 ENST00000455401.2
transgelin 3
chr7_+_99717230 0.85 ENST00000262932.3
canopy FGF signaling regulator 4
chr2_-_224467093 0.85 ENST00000305409.2
secretogranin II
chr4_-_46126093 0.85 ENST00000295452.4
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr7_-_7575477 0.84 ENST00000399429.3
collagen, type XXVIII, alpha 1
chr7_-_107443652 0.84 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
solute carrier family 26 (anion exchanger), member 3
chr19_+_45417921 0.83 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
apolipoprotein C-I
chr2_-_183387064 0.82 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
phosphodiesterase 1A, calmodulin-dependent
chr17_-_64225508 0.81 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr20_+_56136136 0.80 ENST00000319441.4
ENST00000543666.1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr1_+_161190160 0.80 ENST00000594609.1
Uncharacterized protein
chr5_-_173217916 0.80 ENST00000523617.1
CTB-43E15.4
chr7_-_99716914 0.80 ENST00000431404.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr4_-_176733377 0.79 ENST00000505375.1
glycoprotein M6A
chr8_+_98900132 0.79 ENST00000520016.1
matrilin 2
chr1_+_160370344 0.78 ENST00000368061.2
VANGL planar cell polarity protein 2
chr6_+_25652432 0.78 ENST00000377961.2
secretagogin, EF-hand calcium binding protein
chr17_+_1674982 0.77 ENST00000572048.1
ENST00000573763.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr2_+_228736321 0.75 ENST00000309931.2
dynein assembly factor with WDR repeat domains 1
chrX_+_43515467 0.74 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chr14_-_94789663 0.74 ENST00000557225.1
ENST00000341584.3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr6_+_149721495 0.73 ENST00000326669.4
small ubiquitin-like modifier 4
chr14_+_101359265 0.73 ENST00000599197.1
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr8_-_49834299 0.73 ENST00000396822.1
snail family zinc finger 2
chr4_-_185275104 0.72 ENST00000317596.3
RP11-290F5.2
chr5_-_173217931 0.71 ENST00000522731.1
CTB-43E15.4
chr3_-_100565249 0.71 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI family, member 3 (NESH) binding protein
chr19_-_36001113 0.71 ENST00000434389.1
dermokine
chr2_-_224467002 0.71 ENST00000421386.1
ENST00000433889.1
secretogranin II
chr5_-_160279207 0.70 ENST00000327245.5
ATPase, class V, type 10B
chr5_+_140529630 0.70 ENST00000543635.1
protocadherin beta 6
chr8_-_66474884 0.70 ENST00000520902.1
CTD-3025N20.2
chr10_-_135379132 0.69 ENST00000343131.5
synaptonemal complex central element protein 1
chr4_-_16675930 0.69 ENST00000503178.2
LIM domain binding 2
chr8_+_92261516 0.69 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr11_-_117748138 0.68 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr4_+_70796784 0.68 ENST00000246891.4
ENST00000444405.3
casein alpha s1
chr8_-_86253888 0.68 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
carbonic anhydrase I
chr15_+_43886057 0.67 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
creatine kinase, mitochondrial 1B
chr11_-_13517565 0.66 ENST00000282091.1
ENST00000529816.1
parathyroid hormone
chr1_+_86934526 0.66 ENST00000394711.1
chloride channel accessory 1
chr14_-_67878917 0.66 ENST00000216446.4
pleckstrin 2
chr4_-_69434245 0.66 ENST00000317746.2
UDP glucuronosyltransferase 2 family, polypeptide B17
chr15_+_43985725 0.66 ENST00000413453.2
creatine kinase, mitochondrial 1A
chr3_-_120400960 0.66 ENST00000476082.2
homogentisate 1,2-dioxygenase
chr7_+_134528635 0.65 ENST00000445569.2
caldesmon 1
chr10_-_128110441 0.65 ENST00000456514.1
long intergenic non-protein coding RNA 601
chr3_+_149191723 0.65 ENST00000305354.4
transmembrane 4 L six family member 4
chr7_+_142982023 0.63 ENST00000359333.3
ENST00000409244.1
ENST00000409541.1
ENST00000410004.1
transmembrane protein 139
chr6_+_25652501 0.63 ENST00000334979.6
secretagogin, EF-hand calcium binding protein
chr21_+_17442799 0.62 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
long intergenic non-protein coding RNA 478
chr12_+_20963632 0.62 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr10_-_96829246 0.60 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr12_-_15374328 0.60 ENST00000537647.1
RAS-like, estrogen-regulated, growth inhibitor
chr14_+_24540046 0.60 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
copine VI (neuronal)
chr2_+_191221240 0.60 ENST00000409027.1
ENST00000458193.1
inositol polyphosphate-1-phosphatase
chr12_-_48164812 0.58 ENST00000549151.1
ENST00000548919.1
Rap guanine nucleotide exchange factor (GEF) 3
chr11_-_26593649 0.58 ENST00000455601.2
mucin 15, cell surface associated
chr16_+_82068585 0.57 ENST00000563491.1
hydroxysteroid (17-beta) dehydrogenase 2
chr4_-_186696425 0.57 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chr12_-_16760021 0.57 ENST00000540445.1
LIM domain only 3 (rhombotin-like 2)
chr19_+_58570605 0.56 ENST00000359978.6
ENST00000401053.4
ENST00000439855.2
ENST00000313434.5
ENST00000511556.1
ENST00000506786.1
zinc finger protein 135
chr2_+_108863651 0.55 ENST00000329106.2
ENST00000376700.1
sulfotransferase family, cytosolic, 1C, member 3
chr10_-_105845674 0.55 ENST00000353479.5
ENST00000369733.3
collagen, type XVII, alpha 1
chr11_+_27076764 0.55 ENST00000525090.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr11_+_65554493 0.55 ENST00000335987.3
ovo-like zinc finger 1
chr10_+_5238793 0.55 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr12_-_15815626 0.54 ENST00000540613.1
epidermal growth factor receptor pathway substrate 8
chr3_+_111718173 0.54 ENST00000494932.1
transgelin 3
chr5_-_42812143 0.54 ENST00000514985.1
selenoprotein P, plasma, 1
chr11_-_117747434 0.53 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chr5_-_41213607 0.53 ENST00000337836.5
ENST00000433294.1
complement component 6
chr1_+_28261492 0.53 ENST00000373894.3
sphingomyelin phosphodiesterase, acid-like 3B
chr5_-_137475071 0.53 ENST00000265191.2
NME/NM23 family member 5
chr5_+_140557371 0.52 ENST00000239444.2
protocadherin beta 8
chr17_+_48823975 0.52 ENST00000513969.1
ENST00000503728.1
LUC7-like 3 (S. cerevisiae)
chr3_+_138340049 0.52 ENST00000464668.1
Fas apoptotic inhibitory molecule
chr3_-_160823158 0.52 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_+_196743912 0.51 ENST00000367425.4
complement factor H-related 3
chr11_-_117747607 0.51 ENST00000540359.1
ENST00000539526.1
FXYD domain containing ion transport regulator 6
chr11_+_27015628 0.51 ENST00000318627.2
fin bud initiation factor homolog (zebrafish)
chr11_-_111649074 0.51 ENST00000534218.1
RP11-108O10.2
chr2_+_201450591 0.50 ENST00000374700.2
aldehyde oxidase 1
chr15_+_62853562 0.50 ENST00000561311.1
talin 2
chr2_-_43266680 0.50 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2
chr2_-_183387430 0.50 ENST00000410103.1
phosphodiesterase 1A, calmodulin-dependent
chr13_-_86373536 0.49 ENST00000400286.2
SLIT and NTRK-like family, member 6
chr12_-_127544894 0.49 ENST00000546062.1
ENST00000512624.2
ENST00000540244.1
RP11-575F12.1
chr2_-_112237835 0.49 ENST00000442293.1
ENST00000439494.1
MIR4435-1 host gene (non-protein coding)
chr16_+_82068873 0.48 ENST00000566213.1
hydroxysteroid (17-beta) dehydrogenase 2
chr1_-_201140673 0.48 ENST00000367333.2
transmembrane protein 9
chr10_-_135379074 0.48 ENST00000303903.6
synaptonemal complex central element protein 1
chr16_-_28937027 0.48 ENST00000358201.4
rabaptin, RAB GTPase binding effector protein 2
chr6_-_138833630 0.48 ENST00000533765.1
NHS-like 1
chr6_+_160542870 0.47 ENST00000324965.4
ENST00000457470.2
solute carrier family 22 (organic cation transporter), member 1
chr15_+_84115868 0.47 ENST00000427482.2
SH3-domain GRB2-like 3
chr14_+_37641012 0.47 ENST00000556667.1
SLC25A21 antisense RNA 1
chr3_-_151034734 0.47 ENST00000260843.4
G protein-coupled receptor 87
chr6_+_160542821 0.47 ENST00000366963.4
solute carrier family 22 (organic cation transporter), member 1
chr4_-_66536057 0.47 ENST00000273854.3
EPH receptor A5
chr5_-_96478466 0.46 ENST00000274382.4
Lix1 homolog (chicken)
chr8_-_124741451 0.46 ENST00000520519.1
annexin A13
chr1_+_50575292 0.46 ENST00000371821.1
ENST00000371819.1
ELAV like neuron-specific RNA binding protein 4
chr6_+_46761118 0.46 ENST00000230588.4
meprin A, alpha (PABA peptide hydrolase)
chr7_-_44580861 0.45 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1-like 1
chr9_+_130911723 0.45 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
lipocalin 2
chr10_-_13043697 0.45 ENST00000378825.3
coiled-coil domain containing 3
chr3_-_160823040 0.45 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr9_-_73477826 0.45 ENST00000396285.1
ENST00000396292.4
ENST00000396280.5
ENST00000358082.3
ENST00000408909.2
ENST00000377097.3
transient receptor potential cation channel, subfamily M, member 3
chr15_-_54051831 0.45 ENST00000557913.1
ENST00000360509.5
WD repeat domain 72
chrX_-_16887963 0.44 ENST00000380084.4
retinoblastoma binding protein 7
chr6_+_168418553 0.44 ENST00000354419.2
ENST00000351261.3
kinesin family member 25
chr18_-_48351743 0.44 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
maestro
chr3_+_115342349 0.44 ENST00000393780.3
growth associated protein 43
chr7_+_150020363 0.43 ENST00000359623.4
ENST00000493307.1
leucine rich repeat containing 61
chr5_-_42811986 0.43 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr3_-_20053741 0.43 ENST00000389050.4
protein phosphatase 2C-like domain containing 1
chr2_-_169887827 0.43 ENST00000263817.6
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr3_-_164796269 0.43 ENST00000264382.3
sucrase-isomaltase (alpha-glucosidase)
chr17_-_19364269 0.43 ENST00000421796.2
ENST00000585389.1
ENST00000609249.1
AC004448.5
chr10_+_7745232 0.42 ENST00000358415.4
inter-alpha-trypsin inhibitor heavy chain 2
chr8_-_41166953 0.42 ENST00000220772.3
secreted frizzled-related protein 1
chr11_-_63376013 0.42 ENST00000540943.1
phospholipase A2, group XVI
chr7_-_150020750 0.42 ENST00000539352.1
ARP3 actin-related protein 3 homolog C (yeast)
chr1_-_242612779 0.41 ENST00000427495.1
phospholipase D family, member 5
chr2_-_89160770 0.41 ENST00000390240.2
immunoglobulin kappa joining 3
chr7_-_14029283 0.41 ENST00000433547.1
ENST00000405192.2
ets variant 1
chr7_-_83278322 0.41 ENST00000307792.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr1_-_112032284 0.41 ENST00000414219.1
adenosine A3 receptor
chr6_-_138866823 0.41 ENST00000342260.5
NHS-like 1
chr7_+_100547156 0.41 ENST00000379458.4
Protein LOC100131514
chr3_-_194072019 0.41 ENST00000429275.1
ENST00000323830.3
carboxypeptidase N, polypeptide 2
chr12_-_71533055 0.41 ENST00000552128.1
tetraspanin 8
chr7_-_82792215 0.41 ENST00000333891.9
ENST00000423517.2
piccolo presynaptic cytomatrix protein
chr11_-_129062093 0.41 ENST00000310343.9
Rho GTPase activating protein 32
chr4_+_80584903 0.41 ENST00000506460.1
RP11-452C8.1
chr12_-_16760195 0.40 ENST00000546281.1
ENST00000537757.1
LIM domain only 3 (rhombotin-like 2)
chr14_-_25479811 0.40 ENST00000550887.1
syntaxin binding protein 6 (amisyn)
chr21_-_31588365 0.40 ENST00000399899.1
claudin 8
chr10_+_7745303 0.40 ENST00000429820.1
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr17_-_72772462 0.39 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
N-acetyltransferase 9 (GCN5-related, putative)
chr10_+_81891416 0.39 ENST00000372270.2
placenta-specific 9
chr18_+_61616510 0.39 ENST00000408945.3
histocompatibility (minor) serpin domain containing
chr6_-_112575912 0.39 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
laminin, alpha 4
chr9_-_75488984 0.39 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1
chr5_+_63802109 0.39 ENST00000334025.2
regulator of G-protein signaling 7 binding protein
chr3_-_12587055 0.39 ENST00000564146.3
chromosome 3 open reading frame 83
chr4_-_34271356 0.39 ENST00000514877.1
RP11-548L20.1
chr6_-_169654139 0.38 ENST00000366787.3
thrombospondin 2
chr4_-_150736962 0.38 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1
chr19_+_49199209 0.38 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
fucosyltransferase 2 (secretor status included)
chr11_-_26593779 0.38 ENST00000529533.1
mucin 15, cell surface associated

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX1_HOXA3_BARX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.3 1.3 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.3 1.4 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.3 0.8 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.7 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 0.7 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.2 0.7 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.2 0.7 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 1.3 GO:0061107 seminal vesicle development(GO:0061107)
0.2 0.8 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.2 0.8 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 1.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.8 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.2 3.8 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 0.2 GO:0006711 estrogen catabolic process(GO:0006711)
0.2 1.5 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.2 1.1 GO:0050955 thermoception(GO:0050955)
0.1 0.6 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.4 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.4 GO:1904956 neural crest cell fate commitment(GO:0014034) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.9 GO:0048241 epinephrine transport(GO:0048241)
0.1 1.7 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 1.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.5 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 1.0 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.6 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.5 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.6 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.5 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 1.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 2.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 1.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 1.6 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.6 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.4 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.3 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 1.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.5 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 0.5 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.1 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993)
0.1 0.2 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.1 1.5 GO:0019532 oxalate transport(GO:0019532)
0.1 0.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.2 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.9 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 0.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.9 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.2 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 0.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 0.3 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.2 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.4 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.4 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.3 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.9 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.2 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.8 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.7 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.3 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.2 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.2 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.0 0.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.2 GO:0061150 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 1.3 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 1.8 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.3 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.8 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.4 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 1.2 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 1.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.4 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.3 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:1904468 negative regulation of tumor necrosis factor secretion(GO:1904468)
0.0 1.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.4 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 1.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 1.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.2 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.3 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 1.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.7 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 1.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.4 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.3 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.6 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.3 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.4 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.4 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.2 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.4 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 1.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.4 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.3 GO:0007565 female pregnancy(GO:0007565)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 2.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.5 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.4 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 1.3 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.0 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 1.4 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.0 GO:0008542 visual learning(GO:0008542)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 1.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.0 GO:1903961 positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.4 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.7 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.4 GO:0035418 protein localization to synapse(GO:0035418)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0097181 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.2 0.8 GO:0060187 cell pole(GO:0060187)
0.2 1.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.2 GO:0000801 central element(GO:0000801)
0.1 0.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.3 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 1.9 GO:0042627 chylomicron(GO:0042627)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.6 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 1.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 5.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.8 GO:0043203 axon hillock(GO:0043203)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.7 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.8 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 3.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.5 GO:0044297 cell body(GO:0044297)
0.0 2.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.3 GO:0044754 autolysosome(GO:0044754)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.2 GO:0072562 blood microparticle(GO:0072562)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.3 1.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 1.9 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.3 0.8 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2 0.7 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.2 1.0 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.2 1.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 0.9 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.2 0.8 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 1.6 GO:0004064 arylesterase activity(GO:0004064)
0.2 0.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 0.7 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 0.9 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.2 0.5 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.2 1.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.4 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.1 1.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 1.3 GO:0032190 acrosin binding(GO:0032190)
0.1 0.4 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.6 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.3 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 1.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.8 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.3 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.2 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.8 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.3 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.2 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.1 0.2 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1 0.7 GO:0031386 protein tag(GO:0031386)
0.1 0.3 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.3 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.3 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0070404 NADH binding(GO:0070404)
0.1 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 1.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.4 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 1.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.9 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 2.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.7 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0003774 motor activity(GO:0003774)
0.0 0.4 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 3.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0070330 aromatase activity(GO:0070330)
0.0 0.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 1.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 4.2 GO:0008083 growth factor activity(GO:0008083)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 4.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.4 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.7 GO:0005262 calcium channel activity(GO:0005262)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 2.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.3 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 5.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 0.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 1.9 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 1.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 2.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane