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Illumina Body Map 2, young vs old

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Results for DPRX

Z-value: 0.20

Motif logo

Transcription factors associated with DPRX

Gene Symbol Gene ID Gene Info
ENSG00000204595.1 divergent-paired related homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DPRXhg19_v2_chr19_+_54135310_54135310-0.336.8e-02Click!

Activity profile of DPRX motif

Sorted Z-values of DPRX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_64271316 2.83 ENST00000540086.1
ENST00000580157.1
cadherin 19, type 2
chr18_-_64271363 2.43 ENST00000262150.2
cadherin 19, type 2
chr10_-_104178857 1.86 ENST00000020673.5
pleckstrin and Sec7 domain containing
chr6_-_84418432 1.56 ENST00000519825.1
ENST00000523484.2
synaptosomal-associated protein, 91kDa
chr18_-_40857493 1.48 ENST00000255224.3
synaptotagmin IV
chr6_-_84418841 1.41 ENST00000369694.2
ENST00000195649.6
synaptosomal-associated protein, 91kDa
chr16_+_81272287 1.36 ENST00000425577.2
ENST00000564552.1
beta-carotene 15,15'-monooxygenase 1
chr16_-_15950868 1.34 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
myosin, heavy chain 11, smooth muscle
chrX_+_100333709 1.22 ENST00000372930.4
transmembrane protein 35
chrX_-_138724994 1.22 ENST00000536274.1
MCF.2 cell line derived transforming sequence
chr20_+_10199566 1.22 ENST00000430336.1
synaptosomal-associated protein, 25kDa
chr12_+_6949964 1.18 ENST00000541978.1
ENST00000435982.2
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr6_-_84418860 1.18 ENST00000521743.1
synaptosomal-associated protein, 91kDa
chr2_-_235405168 1.08 ENST00000339728.3
ADP-ribosylation factor-like 4C
chr1_+_20396649 1.06 ENST00000375108.3
phospholipase A2, group V
chr13_-_45775162 1.00 ENST00000405872.1
potassium channel tetramerization domain containing 4
chr1_+_50569575 0.96 ENST00000371827.1
ELAV like neuron-specific RNA binding protein 4
chrX_-_138724677 0.93 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF.2 cell line derived transforming sequence
chr9_-_23821273 0.93 ENST00000380110.4
ELAV like neuron-specific RNA binding protein 2
chr22_+_23161491 0.92 ENST00000390316.2
immunoglobulin lambda variable 3-9 (gene/pseudogene)
chr2_-_158184211 0.91 ENST00000397283.2
ermin, ERM-like protein
chr14_+_92789498 0.86 ENST00000531433.1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr14_+_22670455 0.86 ENST00000390460.1
T cell receptor alpha variable 26-2
chr7_-_135412925 0.85 ENST00000354042.4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr22_-_38480100 0.85 ENST00000427592.1
solute carrier family 16 (monocarboxylate transporter), member 8
chr18_-_70532906 0.85 ENST00000299430.2
ENST00000397929.1
neuropilin (NRP) and tolloid (TLL)-like 1
chr6_-_84418738 0.84 ENST00000519779.1
synaptosomal-associated protein, 91kDa
chr1_+_115642293 0.77 ENST00000448680.1
RP4-666F24.3
chr14_-_101034407 0.76 ENST00000443071.2
ENST00000557378.1
brain-enriched guanylate kinase-associated
chr5_-_66492562 0.74 ENST00000256447.4
CD180 molecule
chr15_+_34260921 0.74 ENST00000560035.1
cholinergic receptor, muscarinic 5
chr14_+_62585332 0.72 ENST00000554895.1
long intergenic non-protein coding RNA 643
chr20_-_54580523 0.72 ENST00000064571.2
cerebellin 4 precursor
chr14_+_22265444 0.71 ENST00000390430.2
T cell receptor alpha variable 8-1
chr16_-_30022735 0.71 ENST00000564944.1
double C2-like domains, alpha
chr22_+_32754139 0.69 ENST00000382088.3
ret finger protein-like 3
chr4_+_36283213 0.68 ENST00000357504.3
death domain containing 1
chr21_+_19617140 0.68 ENST00000299295.2
ENST00000338326.3
chondrolectin
chr6_+_43215727 0.68 ENST00000304139.5
tau tubulin kinase 1
chr1_+_36023370 0.67 ENST00000356090.4
ENST00000373243.2
neurochondrin
chr11_+_61522844 0.66 ENST00000265460.5
myelin regulatory factor
chr8_+_65285851 0.66 ENST00000520799.1
ENST00000521441.1
long intergenic non-protein coding RNA 966
chr6_-_40555176 0.64 ENST00000338305.6
leucine rich repeat and fibronectin type III domain containing 2
chr17_+_12626199 0.64 ENST00000609971.1
AC005358.1
chr6_-_128239749 0.64 ENST00000537166.1
thymocyte selection associated
chr19_+_39930212 0.63 ENST00000396843.1
Interleukin-like; Uncharacterized protein
chr6_-_128239685 0.63 ENST00000368250.1
thymocyte selection associated
chr1_-_102312600 0.61 ENST00000359814.3
olfactomedin 3
chr8_-_79717750 0.60 ENST00000263851.4
ENST00000379113.2
interleukin 7
chr18_-_3845321 0.57 ENST00000539435.1
ENST00000400147.2
discs, large (Drosophila) homolog-associated protein 1
chr4_-_103997862 0.56 ENST00000394785.3
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr2_-_30144432 0.55 ENST00000389048.3
anaplastic lymphoma receptor tyrosine kinase
chr5_-_45696253 0.54 ENST00000303230.4
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr20_+_123010 0.54 ENST00000382398.3
defensin, beta 126
chr14_+_22204418 0.52 ENST00000390426.2
T cell receptor alpha variable 4
chr4_-_103998060 0.52 ENST00000339611.4
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr10_+_118187379 0.52 ENST00000369230.3
pancreatic lipase-related protein 3
chr8_-_95274536 0.52 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr11_-_10715287 0.51 ENST00000423302.2
murine retrovirus integration site 1 homolog
chr11_-_2323290 0.50 ENST00000381153.3
chromosome 11 open reading frame 21
chr8_-_79717163 0.50 ENST00000520269.1
interleukin 7
chr4_-_164534657 0.50 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr8_-_120605194 0.50 ENST00000522167.1
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr4_+_159131630 0.49 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
transmembrane protein 144
chr15_+_29211570 0.49 ENST00000558804.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr12_-_71182695 0.48 ENST00000342084.4
protein tyrosine phosphatase, receptor type, R
chr19_-_13734804 0.47 ENST00000574974.1
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr17_-_72348271 0.46 ENST00000599136.1
Uncharacterized protein; cDNA FLJ33592 fis, clone BRAMY2012691
chr1_+_207262578 0.46 ENST00000243611.5
ENST00000367076.3
complement component 4 binding protein, beta
chr1_-_152086556 0.46 ENST00000368804.1
trichohyalin
chr3_+_111393501 0.46 ENST00000393934.3
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr15_+_96904487 0.46 ENST00000600790.1
Uncharacterized protein
chr1_+_36024107 0.44 ENST00000437806.1
neurochondrin
chr4_-_103998439 0.44 ENST00000503230.1
ENST00000503818.1
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr10_-_72362515 0.44 ENST00000373209.2
ENST00000441259.1
perforin 1 (pore forming protein)
chr1_-_102312517 0.43 ENST00000338858.5
olfactomedin 3
chr7_+_28452130 0.43 ENST00000357727.2
cAMP responsive element binding protein 5
chr11_-_104905840 0.43 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr1_+_207262627 0.42 ENST00000391923.1
complement component 4 binding protein, beta
chr1_+_120049826 0.41 ENST00000369413.3
ENST00000235547.6
ENST00000528909.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr2_-_26700900 0.41 ENST00000338581.6
ENST00000339598.3
ENST00000402415.3
otoferlin
chr22_-_19137796 0.41 ENST00000086933.2
goosecoid homeobox 2
chr1_+_74701062 0.40 ENST00000326637.3
TNNI3 interacting kinase
chrX_+_71996972 0.39 ENST00000334036.5
DMRT-like family C1B
chr8_+_38244638 0.39 ENST00000526356.1
leucine zipper-EF-hand containing transmembrane protein 2
chr12_-_95010147 0.39 ENST00000548918.1
transmembrane and coiled-coil domain family 3
chr18_-_3845293 0.38 ENST00000400145.2
discs, large (Drosophila) homolog-associated protein 1
chr14_-_101034811 0.38 ENST00000553553.1
brain-enriched guanylate kinase-associated
chr1_+_207262170 0.38 ENST00000367078.3
complement component 4 binding protein, beta
chr14_-_106518922 0.38 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr4_-_123542224 0.38 ENST00000264497.3
interleukin 21
chr17_+_48911942 0.38 ENST00000426127.1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr3_-_167371740 0.37 ENST00000466760.1
ENST00000479765.1
WD repeat domain 49
chr4_+_57396766 0.36 ENST00000512175.2
theg spermatid protein-like
chr7_-_84121858 0.36 ENST00000448879.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr6_-_41122063 0.36 ENST00000426005.2
ENST00000437044.2
ENST00000373127.4
triggering receptor expressed on myeloid cells-like 1
chr12_-_9913489 0.36 ENST00000228434.3
ENST00000536709.1
CD69 molecule
chr3_+_10068095 0.36 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
Fanconi anemia, complementation group D2
chr4_+_113970772 0.36 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ankyrin 2, neuronal
chr5_+_132083106 0.35 ENST00000378731.1
cyclin I family, member 2
chr8_-_101157680 0.35 ENST00000428847.2
F-box protein 43
chr1_+_190448095 0.35 ENST00000424735.1
RP11-547I7.2
chr9_-_13432977 0.35 ENST00000605459.1
RP11-536O18.2
chr7_+_134464376 0.35 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chr13_-_44980021 0.35 ENST00000432701.2
ENST00000607312.1
long intergenic non-protein coding RNA 1071
chr17_+_43318434 0.35 ENST00000587489.1
formin-like 1
chrX_-_140336629 0.34 ENST00000358993.2
SPANX family, member C
chr17_-_19771216 0.34 ENST00000395544.4
unc-51 like autophagy activating kinase 2
chr20_+_1875942 0.34 ENST00000358771.4
signal-regulatory protein alpha
chr3_+_45984947 0.34 ENST00000304552.4
chemokine (C-X-C motif) receptor 6
chr14_-_21056121 0.34 ENST00000557105.1
ENST00000398008.2
ENST00000555841.1
ENST00000443456.2
ENST00000432835.2
ENST00000557503.1
ENST00000398009.2
ENST00000554842.1
ribonuclease, RNase A family, 11 (non-active)
chr1_-_173174681 0.33 ENST00000367718.1
tumor necrosis factor (ligand) superfamily, member 4
chrX_+_15767971 0.33 ENST00000479740.1
ENST00000454127.2
carbonic anhydrase VB, mitochondrial
chr11_+_60383204 0.33 ENST00000412599.1
ENST00000320202.4
long intergenic non-protein coding RNA 301
chr1_+_202431859 0.33 ENST00000391959.3
ENST00000367270.4
protein phosphatase 1, regulatory subunit 12B
chr7_-_142224280 0.32 ENST00000390367.3
T cell receptor beta variable 11-1
chr4_-_87374330 0.32 ENST00000511328.1
ENST00000503911.1
mitogen-activated protein kinase 10
chr3_+_132757215 0.31 ENST00000321871.6
ENST00000393130.3
ENST00000514894.1
ENST00000512662.1
transmembrane protein 108
chr18_+_32290218 0.31 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
dystrobrevin, alpha
chr17_-_15244894 0.31 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
tektin 3
chrX_+_139791917 0.30 ENST00000607004.1
ENST00000370535.3
long intergenic non-protein coding RNA 632
chr11_-_2323089 0.30 ENST00000456145.2
chromosome 11 open reading frame 21
chr3_+_40351169 0.30 ENST00000232905.3
eukaryotic translation initiation factor 1B
chr11_+_61248583 0.29 ENST00000432063.2
ENST00000338608.2
protein phosphatase 1, regulatory subunit 32
chr5_+_169010638 0.29 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
spindle apparatus coiled-coil protein 1
chr5_-_54988559 0.29 ENST00000502247.1
solute carrier family 38, member 9
chr4_-_87279520 0.29 ENST00000506773.1
mitogen-activated protein kinase 10
chr19_-_14628234 0.29 ENST00000595139.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr15_-_83240783 0.29 ENST00000568994.1
cytoplasmic polyadenylation element binding protein 1
chr2_+_7118755 0.29 ENST00000433456.1
ring finger protein 144A
chr15_+_34261089 0.29 ENST00000383263.5
cholinergic receptor, muscarinic 5
chr1_+_202317815 0.29 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr1_-_236046872 0.28 ENST00000536965.1
lysosomal trafficking regulator
chr1_-_209741018 0.28 ENST00000424696.2
RP1-272L16.1
chr6_-_32784687 0.28 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr14_-_69446034 0.28 ENST00000193403.6
actinin, alpha 1
chr8_-_145701718 0.28 ENST00000377317.4
forkhead box H1
chr12_-_7848364 0.27 ENST00000329913.3
growth differentiation factor 3
chr11_-_85430356 0.27 ENST00000526999.1
synaptotagmin-like 2
chr1_+_207262540 0.27 ENST00000452902.2
complement component 4 binding protein, beta
chr18_+_13465008 0.27 ENST00000593236.1
low density lipoprotein receptor class A domain containing 4
chr11_-_104916034 0.27 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
caspase recruitment domain family, member 16
chr2_+_33701286 0.27 ENST00000403687.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr6_+_31555045 0.27 ENST00000396101.3
ENST00000490742.1
leukocyte specific transcript 1
chr8_+_72755367 0.27 ENST00000537896.1
Protein LOC100132891; cDNA FLJ53548
chr19_-_14628645 0.27 ENST00000598235.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr11_+_2323236 0.27 ENST00000182290.4
tetraspanin 32
chr17_-_73150629 0.27 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
hematological and neurological expressed 1
chr12_+_54891495 0.27 ENST00000293373.6
NCK-associated protein 1-like
chr22_-_36903101 0.26 ENST00000397224.4
FAD-dependent oxidoreductase domain containing 2
chr20_+_8112824 0.26 ENST00000378641.3
phospholipase C, beta 1 (phosphoinositide-specific)
chr14_+_22931924 0.26 ENST00000390477.2
T cell receptor delta constant
chr14_-_22005343 0.26 ENST00000327430.3
spalt-like transcription factor 2
chr14_-_22005062 0.25 ENST00000317492.5
spalt-like transcription factor 2
chr3_+_111393659 0.25 ENST00000477665.1
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr9_+_37667978 0.25 ENST00000539465.1
FERM and PDZ domain containing 1
chr16_-_46723066 0.25 ENST00000299138.7
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr8_-_37411648 0.25 ENST00000519738.1
RP11-150O12.1
chr6_+_130339710 0.25 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr11_+_2323349 0.24 ENST00000381121.3
tetraspanin 32
chr11_-_65629497 0.24 ENST00000532134.1
cofilin 1 (non-muscle)
chr18_-_67614645 0.24 ENST00000577287.1
CD226 molecule
chr17_+_41150290 0.24 ENST00000589037.1
ENST00000253788.5
ribosomal protein L27
chr1_+_111415757 0.24 ENST00000429072.2
ENST00000271324.5
CD53 molecule
chr12_+_113344755 0.24 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr14_+_77292715 0.24 ENST00000393774.3
ENST00000555189.1
ENST00000450042.2
chromosome 14 open reading frame 166B
chr11_-_104972158 0.24 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr22_-_36903069 0.24 ENST00000216187.6
ENST00000423980.1
FAD-dependent oxidoreductase domain containing 2
chr12_+_86268065 0.24 ENST00000551529.1
ENST00000256010.6
neurotensin
chr14_-_22005197 0.23 ENST00000541965.1
spalt-like transcription factor 2
chr7_+_94537247 0.23 ENST00000422324.1
protein phosphatase 1, regulatory subunit 9A
chr11_-_8816375 0.23 ENST00000530580.1
suppression of tumorigenicity 5
chr14_-_21055874 0.22 ENST00000553849.1
ribonuclease, RNase A family, 11 (non-active)
chr17_-_48785216 0.22 ENST00000285243.6
ankyrin repeat domain 40
chr9_+_17134980 0.22 ENST00000380647.3
centlein, centrosomal protein
chr16_+_63764128 0.22 ENST00000563061.1
RP11-370P15.2
chr11_+_111385497 0.22 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
chromosome 11 open reading frame 88
chr8_+_104384616 0.21 ENST00000520337.1
collagen triple helix repeat containing 1
chr4_-_122791583 0.21 ENST00000506636.1
ENST00000264499.4
Bardet-Biedl syndrome 7
chr16_+_67918708 0.21 ENST00000339176.3
ENST00000576758.1
neuritin 1-like
chr8_+_110656344 0.21 ENST00000499579.1
Uncharacterized protein
chr5_-_9712312 0.21 ENST00000506620.1
ENST00000514078.1
ENST00000606744.1
taste receptor, type 2, member 1
CTD-2143L24.1
chr13_+_52436111 0.21 ENST00000242819.4
coiled-coil domain containing 70
chr4_-_87374283 0.21 ENST00000361569.2
mitogen-activated protein kinase 10
chr3_-_112564797 0.21 ENST00000398214.1
ENST00000448932.1
CD200 receptor 1-like
chr1_-_65533390 0.20 ENST00000448344.1
RP4-535B20.1
chr6_+_31554826 0.20 ENST00000376089.2
ENST00000396112.2
leukocyte specific transcript 1
chr1_+_11824462 0.20 ENST00000435090.1
chromosome 1 open reading frame 167
chr1_-_170043709 0.20 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
kinesin-associated protein 3
chr14_-_106380248 0.20 ENST00000390590.1
immunoglobulin heavy diversity 3-3
chr12_+_103545593 0.20 ENST00000547418.1
Uncharacterized protein
chr14_+_23009190 0.20 ENST00000390532.1
T cell receptor alpha joining 5
chr4_-_87279641 0.19 ENST00000512689.1
mitogen-activated protein kinase 10
chr19_+_41284121 0.19 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
RAB4B, member RAS oncogene family
chr14_-_22005018 0.19 ENST00000546363.1
spalt-like transcription factor 2
chr12_-_49523896 0.19 ENST00000549870.1
tubulin, alpha 1b
chr6_-_35480640 0.19 ENST00000428978.1
ENST00000322263.4
tubby like protein 1
chr1_-_150780757 0.19 ENST00000271651.3
cathepsin K
chr7_+_50135433 0.19 ENST00000297001.6
chromosome 7 open reading frame 72
chr3_-_158390282 0.19 ENST00000264265.3
latexin

Network of associatons between targets according to the STRING database.

First level regulatory network of DPRX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0048174 negative regulation of short-term neuronal synaptic plasticity(GO:0048174)
0.3 1.0 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.3 1.2 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.3 1.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 1.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.2 0.8 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 1.5 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 0.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 1.4 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 0.5 GO:0036269 swimming behavior(GO:0036269)
0.1 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 5.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.6 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.3 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.7 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.5 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.1 0.1 GO:0002652 regulation of tolerance induction dependent upon immune response(GO:0002652)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.3 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.1 0.4 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.2 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.1 0.3 GO:1903181 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.1 1.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 0.5 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.1 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.3 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.4 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 0.7 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.9 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 1.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.7 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 1.1 GO:0043383 negative T cell selection(GO:0043383)
0.1 0.2 GO:0048633 negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.4 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.1 GO:0072738 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 0.2 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.5 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0035627 ceramide transport(GO:0035627)
0.0 0.2 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.6 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.2 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.3 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.2 GO:0051510 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.9 GO:0008272 sulfate transport(GO:0008272)
0.0 0.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.1 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.0 1.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0061364 negative regulation of negative chemotaxis(GO:0050925) apoptotic process involved in luteolysis(GO:0061364)
0.0 0.3 GO:0097106 postsynaptic density organization(GO:0097106)
0.0 1.1 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.9 GO:0097186 amelogenesis(GO:0097186)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.4 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.1 GO:0015755 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.3 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.4 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 4.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.8 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0072757 cellular response to camptothecin(GO:0072757)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 2.1 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 1.1 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0032127 dense core granule membrane(GO:0032127)
0.2 0.5 GO:0098855 HCN channel complex(GO:0098855)
0.2 1.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.9 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.9 GO:0033269 internode region of axon(GO:0033269)
0.1 0.8 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.2 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.4 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 1.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 1.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 5.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0097422 tubular endosome(GO:0097422)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 1.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686) small-subunit processome(GO:0032040)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 5.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.5 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.3 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0016296 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 1.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.0 0.2 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.4 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.9 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.5 GO:0089720 caspase binding(GO:0089720)
0.0 0.4 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.3 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.9 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 2.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 1.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 2.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen