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Illumina Body Map 2, young vs old

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Results for EGR3_EGR2

Z-value: 0.34

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Transcription factors associated with EGR3_EGR2

Gene Symbol Gene ID Gene Info
ENSG00000179388.8 early growth response 3
ENSG00000122877.9 early growth response 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EGR3hg19_v2_chr8_-_22550815_225508440.602.7e-04Click!
EGR2hg19_v2_chr10_-_64576105_645761330.125.1e-01Click!

Activity profile of EGR3_EGR2 motif

Sorted Z-values of EGR3_EGR2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_84115868 5.27 ENST00000427482.2
SH3-domain GRB2-like 3
chr11_+_124609823 3.97 ENST00000412681.2
neurogranin (protein kinase C substrate, RC3)
chr11_+_124609742 3.90 ENST00000284292.6
neurogranin (protein kinase C substrate, RC3)
chrX_+_117957741 3.51 ENST00000310164.2
zinc finger, CCHC domain containing 12
chr15_+_84116106 3.43 ENST00000535412.1
ENST00000324537.5
SH3-domain GRB2-like 3
chr19_+_10400615 3.15 ENST00000221980.4
intercellular adhesion molecule 5, telencephalin
chr16_+_25703274 3.07 ENST00000331351.5
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr11_-_18813110 2.86 ENST00000396168.1
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr19_+_49617581 2.71 ENST00000391864.3
lin-7 homolog B (C. elegans)
chr4_-_90758227 2.63 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
synuclein, alpha (non A4 component of amyloid precursor)
chr17_+_37782955 2.61 ENST00000580825.1
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr19_-_13617247 2.58 ENST00000573710.2
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr20_+_37353084 2.44 ENST00000217420.1
solute carrier family 32 (GABA vesicular transporter), member 1
chr6_-_110500826 2.42 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WAS protein family, member 1
chr19_+_49617609 2.40 ENST00000221459.2
ENST00000486217.2
lin-7 homolog B (C. elegans)
chr19_+_589893 2.37 ENST00000251287.2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr4_+_150999418 2.36 ENST00000296550.7
doublecortin-like kinase 2
chrX_-_128788914 2.36 ENST00000429967.1
ENST00000307484.6
apelin
chr1_-_35395178 2.36 ENST00000373347.1
discs, large (Drosophila) homolog-associated protein 3
chr4_-_90758118 2.30 ENST00000420646.2
synuclein, alpha (non A4 component of amyloid precursor)
chr6_+_99282570 2.29 ENST00000328345.5
POU class 3 homeobox 2
chr19_+_35634146 2.28 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD domain containing ion transport regulator 7
chr11_-_18765389 2.25 ENST00000477854.1
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr5_+_7396141 2.25 ENST00000338316.4
adenylate cyclase 2 (brain)
chr6_-_110500905 2.20 ENST00000392587.2
WAS protein family, member 1
chr9_+_140772226 2.19 ENST00000277551.2
ENST00000371372.1
ENST00000277549.5
ENST00000371363.1
ENST00000371357.1
ENST00000371355.4
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr11_-_18813353 2.17 ENST00000358540.2
ENST00000396171.4
ENST00000396167.2
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chrX_-_47479246 2.17 ENST00000295987.7
ENST00000340666.4
synapsin I
chr2_+_220306745 2.11 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG complex locus
chrX_+_49126294 2.08 ENST00000466508.1
ENST00000438316.1
ENST00000055335.6
ENST00000495799.1
protein phosphatase 1, regulatory subunit 3F
chr19_-_40724246 2.06 ENST00000311308.6
tetratricopeptide repeat domain 9B
chr22_+_19702069 2.06 ENST00000412544.1
septin 5
chr7_-_100493482 2.00 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
acetylcholinesterase (Yt blood group)
chr17_+_30593195 2.00 ENST00000431505.2
ENST00000269051.4
ENST00000538145.1
rhomboid, veinlet-like 3 (Drosophila)
chr15_-_83316711 1.99 ENST00000568128.1
cytoplasmic polyadenylation element binding protein 1
chr12_+_79258444 1.98 ENST00000261205.4
synaptotagmin I
chr19_-_51472031 1.98 ENST00000391808.1
kallikrein-related peptidase 6
chr20_+_44035200 1.97 ENST00000372717.1
ENST00000360981.4
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr12_-_65515334 1.96 ENST00000286574.4
WNT inhibitory factor 1
chr8_+_73449625 1.90 ENST00000523207.1
potassium voltage-gated channel, Shab-related subfamily, member 2
chr9_+_34958254 1.90 ENST00000242315.3
KIAA1045
chr15_-_71146480 1.90 ENST00000299213.8
La ribonucleoprotein domain family, member 6
chr21_+_34398153 1.89 ENST00000382357.3
ENST00000430860.1
ENST00000333337.3
oligodendrocyte lineage transcription factor 2
chr2_-_61108449 1.85 ENST00000439412.1
ENST00000452343.1
AC010733.4
chr19_-_51472222 1.81 ENST00000376851.3
kallikrein-related peptidase 6
chr19_+_54412517 1.78 ENST00000391767.1
calcium channel, voltage-dependent, gamma subunit 7
chr19_+_55795493 1.78 ENST00000309383.1
BR serine/threonine kinase 1
chr12_-_49393092 1.77 ENST00000421952.2
dendrin
chr10_+_105036909 1.77 ENST00000369849.4
internexin neuronal intermediate filament protein, alpha
chr17_-_42992856 1.75 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
glial fibrillary acidic protein
chr3_-_149688655 1.74 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
profilin 2
chr20_+_17207636 1.74 ENST00000262545.2
proprotein convertase subtilisin/kexin type 2
chr11_+_66059339 1.73 ENST00000327259.4
transmembrane protein 151A
chr7_-_100253993 1.73 ENST00000461605.1
ENST00000160382.5
actin-like 6B
chr19_-_38714847 1.72 ENST00000420980.2
ENST00000355526.4
D4, zinc and double PHD fingers family 1
chr1_+_23695680 1.71 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
chromosome 1 open reading frame 213
chr6_+_72596604 1.68 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
regulating synaptic membrane exocytosis 1
chr17_+_37783197 1.67 ENST00000582680.1
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr18_+_33877654 1.66 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
formin homology 2 domain containing 3
chr17_-_36760865 1.65 ENST00000584266.1
SRC kinase signaling inhibitor 1
chr5_+_137774706 1.65 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
receptor accessory protein 2
chr17_+_37783170 1.64 ENST00000254079.4
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr6_-_110501126 1.62 ENST00000368938.1
WAS protein family, member 1
chr7_+_94537542 1.62 ENST00000433881.1
protein phosphatase 1, regulatory subunit 9A
chr14_-_77737543 1.56 ENST00000298352.4
neuroglobin
chr16_-_850723 1.55 ENST00000248150.4
guanine nucleotide binding protein (G protein), gamma 13
chr6_-_110501200 1.55 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WAS protein family, member 1
chr7_+_24323782 1.55 ENST00000242152.2
ENST00000407573.1
neuropeptide Y
chrX_+_130192216 1.55 ENST00000276211.5
Rho GTPase activating protein 36
chr14_-_23822080 1.54 ENST00000397267.1
ENST00000354772.3
solute carrier family 22, member 17
chr16_-_62070305 1.54 ENST00000584337.1
cadherin 8, type 2
chr4_+_158142750 1.54 ENST00000505888.1
ENST00000449365.1
glutamate receptor, ionotropic, AMPA 2
chr18_-_70534745 1.54 ENST00000583169.1
neuropilin (NRP) and tolloid (TLL)-like 1
chr1_+_6845384 1.54 ENST00000303635.7
calmodulin binding transcription activator 1
chr8_-_57233103 1.53 ENST00000303749.3
ENST00000522671.1
short chain dehydrogenase/reductase family 16C, member 5
chr12_+_70760056 1.53 ENST00000258111.4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr3_+_123813509 1.52 ENST00000460856.1
ENST00000240874.3
kalirin, RhoGEF kinase
chr8_+_22019168 1.52 ENST00000318561.3
ENST00000521315.1
ENST00000437090.2
ENST00000520605.1
ENST00000522109.1
ENST00000524255.1
ENST00000523296.1
ENST00000518615.1
surfactant protein C
chr19_-_36523709 1.50 ENST00000592017.1
ENST00000360535.4
CAP-GLY domain containing linker protein 3
chr4_-_36246060 1.49 ENST00000303965.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_+_95401851 1.49 ENST00000447467.2
dynein, cytoplasmic 1, intermediate chain 1
chrX_-_152939133 1.49 ENST00000370150.1
pregnancy up-regulated nonubiquitous CaM kinase
chr20_+_17207665 1.48 ENST00000536609.1
proprotein convertase subtilisin/kexin type 2
chr12_+_79258547 1.48 ENST00000457153.2
synaptotagmin I
chr15_+_43809797 1.48 ENST00000399453.1
ENST00000300231.5
microtubule-associated protein 1A
chr11_+_66045634 1.46 ENST00000528852.1
ENST00000311445.6
cornichon family AMPA receptor auxiliary protein 2
chr2_+_210636697 1.46 ENST00000439458.1
ENST00000272845.6
unc-80 homolog (C. elegans)
chr22_-_38380543 1.45 ENST00000396884.2
SRY (sex determining region Y)-box 10
chr19_-_46145696 1.42 ENST00000588172.1
echinoderm microtubule associated protein like 2
chr14_+_100150622 1.42 ENST00000261835.3
cytochrome P450, family 46, subfamily A, polypeptide 1
chr17_-_77179487 1.42 ENST00000580508.1
RNA binding protein, fox-1 homolog (C. elegans) 3
chr2_-_42721110 1.41 ENST00000394973.4
ENST00000306078.1
potassium voltage-gated channel, subfamily G, member 3
chr19_-_13617037 1.40 ENST00000360228.5
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr1_-_38512450 1.40 ENST00000373012.2
POU class 3 homeobox 1
chr15_+_51633826 1.38 ENST00000335449.6
gliomedin
chr8_-_75233563 1.38 ENST00000342232.4
junctophilin 1
chr10_-_135150367 1.37 ENST00000368555.3
ENST00000252939.4
ENST00000368558.1
ENST00000368556.2
calcyon neuron-specific vesicular protein
chr1_-_160040038 1.36 ENST00000368089.3
potassium inwardly-rectifying channel, subfamily J, member 10
chr21_+_22370717 1.36 ENST00000284894.7
neural cell adhesion molecule 2
chr21_+_22370608 1.36 ENST00000400546.1
neural cell adhesion molecule 2
chr16_-_31021717 1.35 ENST00000565419.1
syntaxin 1B
chr6_-_84419101 1.34 ENST00000520302.1
ENST00000520213.1
ENST00000439399.2
ENST00000428679.2
ENST00000437520.1
synaptosomal-associated protein, 91kDa
chr7_-_44365020 1.33 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
calcium/calmodulin-dependent protein kinase II beta
chr3_-_49907323 1.33 ENST00000296471.7
ENST00000488336.1
ENST00000467248.1
ENST00000466940.1
ENST00000463537.1
ENST00000480398.2
CaM kinase-like vesicle-associated
chr8_-_144242020 1.33 ENST00000414417.2
lymphocyte antigen 6 complex, locus H
chr18_-_70210764 1.32 ENST00000585159.1
ENST00000584764.1
cerebellin 2 precursor
chr22_+_19701985 1.31 ENST00000455784.2
ENST00000406395.1
septin 5
chr3_-_149688896 1.30 ENST00000239940.7
profilin 2
chr20_+_44034676 1.30 ENST00000372723.3
ENST00000372722.3
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr14_+_29234870 1.28 ENST00000382535.3
forkhead box G1
chr9_+_140033862 1.28 ENST00000350902.5
ENST00000371550.4
ENST00000371546.4
ENST00000371555.4
ENST00000371553.3
ENST00000371559.4
ENST00000371560.3
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr12_+_3600356 1.27 ENST00000382622.3
protein arginine methyltransferase 8
chr7_+_95401877 1.26 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
dynein, cytoplasmic 1, intermediate chain 1
chr3_-_149688971 1.26 ENST00000498307.1
ENST00000489155.1
profilin 2
chr15_-_71146460 1.26 ENST00000344870.4
La ribonucleoprotein domain family, member 6
chrX_-_152939252 1.25 ENST00000340888.3
pregnancy up-regulated nonubiquitous CaM kinase
chr3_+_35681081 1.23 ENST00000428373.1
cAMP-regulated phosphoprotein, 21kDa
chr13_+_26042960 1.22 ENST00000255283.8
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr19_-_41196458 1.22 ENST00000598779.1
numb homolog (Drosophila)-like
chr12_-_57634475 1.22 ENST00000393825.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr5_+_161274685 1.20 ENST00000428797.2
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr16_+_5009250 1.20 ENST00000587469.1
SEC14-like 5 (S. cerevisiae)
chr3_-_149688502 1.20 ENST00000481767.1
ENST00000475518.1
profilin 2
chrX_-_49056635 1.19 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
synaptophysin
chr1_+_237205476 1.18 ENST00000366574.2
ryanodine receptor 2 (cardiac)
chr15_+_79575073 1.17 ENST00000421388.2
ankyrin repeat domain 34C
chr8_-_110986918 1.17 ENST00000297404.1
potassium channel, subfamily V, member 1
chr5_+_161274940 1.17 ENST00000393943.4
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr8_-_132052458 1.17 ENST00000377928.3
adenylate cyclase 8 (brain)
chr16_+_77822427 1.16 ENST00000302536.2
vesicle amine transport 1-like
chr14_+_77648167 1.16 ENST00000554346.1
ENST00000298351.4
transmembrane protein 63C
chr19_-_36523529 1.15 ENST00000593074.1
CAP-GLY domain containing linker protein 3
chr15_+_32322685 1.14 ENST00000454250.3
ENST00000306901.3
cholinergic receptor, nicotinic, alpha 7 (neuronal)
chr3_-_52002194 1.13 ENST00000466412.1
poly(rC) binding protein 4
chr16_-_31021921 1.13 ENST00000215095.5
syntaxin 1B
chr2_-_219433014 1.12 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
ubiquitin specific peptidase 37
chr5_+_161275320 1.12 ENST00000437025.2
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr17_+_20059358 1.11 ENST00000536879.1
ENST00000395522.2
ENST00000395525.3
sperm antigen with calponin homology and coiled-coil domains 1
chr17_+_20059302 1.11 ENST00000395530.2
sperm antigen with calponin homology and coiled-coil domains 1
chr10_-_43762329 1.09 ENST00000395810.1
RasGEF domain family, member 1A
chr11_-_125366089 1.09 ENST00000366139.3
ENST00000278919.3
fasciculation and elongation protein zeta 1 (zygin I)
chr14_+_94640633 1.09 ENST00000304338.3
protein phosphatase 4, regulatory subunit 4
chr16_-_49891694 1.07 ENST00000562520.1
zinc finger protein 423
chr3_+_71803201 1.07 ENST00000304411.2
G protein-coupled receptor 27
chr12_+_51984657 1.07 ENST00000550891.1
sodium channel, voltage gated, type VIII, alpha subunit
chrX_-_53350522 1.06 ENST00000396435.3
ENST00000375368.5
IQ motif and Sec7 domain 2
chr15_-_27184664 1.06 ENST00000541819.2
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr16_+_5008290 1.04 ENST00000251170.7
SEC14-like 5 (S. cerevisiae)
chr20_-_41818373 1.04 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
protein tyrosine phosphatase, receptor type, T
chr15_-_83316254 1.03 ENST00000567678.1
ENST00000450751.2
cytoplasmic polyadenylation element binding protein 1
chr19_+_34112850 1.03 ENST00000591231.1
ENST00000434302.1
ENST00000438847.3
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr7_+_103969104 1.03 ENST00000424859.1
ENST00000535008.1
ENST00000401970.2
ENST00000543266.1
lipoma HMGIC fusion partner-like 3
chr16_+_2198604 1.02 ENST00000210187.6
RAB26, member RAS oncogene family
chr5_-_176037105 1.02 ENST00000303991.4
G protein regulated inducer of neurite outgrowth 1
chr2_+_220495800 1.02 ENST00000413743.1
solute carrier family 4 (anion exchanger), member 3
chr7_+_153749732 1.01 ENST00000377770.3
dipeptidyl-peptidase 6
chrX_-_140271249 1.01 ENST00000370526.2
leucine zipper, down-regulated in cancer 1
chr5_+_149569520 1.00 ENST00000230671.2
ENST00000524041.1
solute carrier family 6 (neurotransmitter transporter), member 7
chr7_-_108096822 1.00 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
neuronal cell adhesion molecule
chr3_+_238427 1.00 ENST00000397491.2
cell adhesion molecule L1-like
chrX_+_70364667 0.99 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
neuroligin 3
chr15_-_80695917 0.99 ENST00000559008.1
Uncharacterized protein
chr6_+_72596406 0.98 ENST00000491071.2
regulating synaptic membrane exocytosis 1
chr1_-_37499726 0.98 ENST00000373091.3
ENST00000373093.4
glutamate receptor, ionotropic, kainate 3
chr1_-_23694794 0.98 ENST00000374608.3
zinc finger protein 436
chr4_+_114038137 0.97 ENST00000508613.1
ankyrin 2, neuronal
chr19_-_41196534 0.97 ENST00000252891.4
numb homolog (Drosophila)-like
chr12_-_55375622 0.97 ENST00000316577.8
thymocyte expressed, positive selection associated 1
chr4_+_83351715 0.96 ENST00000273920.3
enolase-phosphatase 1
chr20_-_40247002 0.96 ENST00000373222.3
chromodomain helicase DNA binding protein 6
chr14_+_94640671 0.96 ENST00000328839.3
protein phosphatase 4, regulatory subunit 4
chr8_-_9760839 0.96 ENST00000519461.1
ENST00000517675.1
long intergenic non-protein coding RNA 599
chrX_+_130192318 0.96 ENST00000370922.1
Rho GTPase activating protein 36
chr7_+_86274145 0.95 ENST00000439827.1
ENST00000394720.2
ENST00000421579.1
glutamate receptor, metabotropic 3
chr7_-_108096765 0.94 ENST00000379024.4
ENST00000351718.4
neuronal cell adhesion molecule
chr16_+_23847267 0.94 ENST00000321728.7
protein kinase C, beta
chr19_-_12945362 0.94 ENST00000590404.1
ENST00000592204.1
retbindin
chr11_+_67183141 0.94 ENST00000531040.1
ENST00000307823.3
ENST00000423745.2
carnosine synthase 1
chrX_-_48814810 0.94 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTU domain containing 5
chr13_-_37494365 0.92 ENST00000350148.5
SMAD family member 9
chr8_-_57232656 0.92 ENST00000396721.2
short chain dehydrogenase/reductase family 16C, member 5
chr19_+_30017406 0.92 ENST00000335523.7
V-set and transmembrane domain containing 2B
chr10_-_75255724 0.92 ENST00000342558.3
ENST00000360663.5
ENST00000394829.2
ENST00000394828.2
ENST00000394822.2
protein phosphatase 3, catalytic subunit, beta isozyme
chr20_-_21494654 0.91 ENST00000377142.4
NK2 homeobox 2
chr7_-_100493744 0.91 ENST00000428317.1
ENST00000441605.1
acetylcholinesterase (Yt blood group)
chr1_-_205313304 0.90 ENST00000539253.1
ENST00000607826.1
kelch domain containing 8A
chr17_-_79008373 0.90 ENST00000577066.1
ENST00000573167.1
BAIAP2 antisense RNA 1 (head to head)
chr14_+_65170820 0.89 ENST00000555982.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr6_-_40555176 0.89 ENST00000338305.6
leucine rich repeat and fibronectin type III domain containing 2
chr3_+_167453026 0.89 ENST00000472941.1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr19_-_3801789 0.89 ENST00000590849.1
ENST00000395045.2
megakaryocyte-associated tyrosine kinase
chr3_-_50541028 0.89 ENST00000266039.3
ENST00000435965.1
ENST00000395083.1
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr20_+_53092123 0.89 ENST00000262593.5
docking protein 5
chr11_+_64685026 0.89 ENST00000526559.1
protein phosphatase 2, regulatory subunit B', beta
chrX_+_71996972 0.88 ENST00000334036.5
DMRT-like family C1B
chr13_+_88324870 0.88 ENST00000325089.6
SLIT and NTRK-like family, member 5
chr13_-_38443860 0.88 ENST00000426868.2
ENST00000379681.3
ENST00000338947.5
ENST00000355779.2
ENST00000358477.2
ENST00000379673.2
transient receptor potential cation channel, subfamily C, member 4
chr9_+_129986734 0.88 ENST00000444677.1
GTPase activating Rap/RanGAP domain-like 3
chr11_-_125366018 0.88 ENST00000527534.1
fasciculation and elongation protein zeta 1 (zygin I)
chr15_+_32322709 0.87 ENST00000455693.2
cholinergic receptor, nicotinic, alpha 7 (neuronal)

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR3_EGR2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.9 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.9 2.8 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.8 0.8 GO:0033058 directional locomotion(GO:0033058)
0.8 2.4 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.7 2.9 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.7 10.0 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.7 4.1 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.6 3.2 GO:0030070 insulin processing(GO:0030070)
0.6 3.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.6 2.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.6 5.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.5 5.9 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.5 2.6 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.5 1.9 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.5 1.9 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.4 1.3 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.4 1.3 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.4 2.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.4 5.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.4 1.2 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.4 1.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.4 1.5 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.4 1.4 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.3 1.9 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.3 0.9 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.3 1.5 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3 1.2 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.3 0.9 GO:0060929 Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
0.3 11.0 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.3 2.0 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.3 1.1 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.3 2.6 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.3 5.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 2.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 3.4 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.2 1.8 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2 0.7 GO:0048320 axial mesoderm formation(GO:0048320)
0.2 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.2 1.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.2 0.9 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 2.5 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.8 GO:1903060 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.2 2.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 2.4 GO:0071321 cellular response to cGMP(GO:0071321)
0.2 0.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 1.4 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.2 1.2 GO:0036309 protein localization to M-band(GO:0036309)
0.2 0.8 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 2.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.2 0.6 GO:0072720 response to dithiothreitol(GO:0072720)
0.2 2.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 0.7 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.2 3.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 1.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 2.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.2 0.9 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628) somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.2 3.8 GO:0016540 protein autoprocessing(GO:0016540)
0.2 1.8 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.2 1.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 2.6 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.2 0.8 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 2.6 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2 0.5 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.2 1.6 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 1.5 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.2 1.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 7.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.7 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.0 GO:0060137 maternal process involved in parturition(GO:0060137)
0.1 0.6 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 1.0 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.4 GO:0061193 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 1.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.4 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.1 0.7 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 1.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.5 GO:0071469 sensory perception of touch(GO:0050975) detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 2.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.9 GO:0060025 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) regulation of synaptic activity(GO:0060025)
0.1 0.8 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.5 GO:0036269 swimming behavior(GO:0036269)
0.1 0.4 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 0.4 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 0.5 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 2.7 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 1.7 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.6 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 1.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 1.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.6 GO:0043474 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.1 1.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 1.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.2 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.1 0.9 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.5 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 2.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.7 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 1.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 2.5 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.9 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 1.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.1 0.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.6 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.3 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.2 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 1.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 0.5 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 2.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.4 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 1.0 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.5 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.1 0.5 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 0.3 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.1 3.1 GO:0007413 axonal fasciculation(GO:0007413)
0.1 1.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 1.0 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.3 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.4 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.3 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 1.4 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 1.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.4 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.2 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.6 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.4 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1 1.3 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 0.9 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1 5.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.2 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 2.5 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 0.4 GO:0070458 establishment of blood-nerve barrier(GO:0008065) cellular detoxification of nitrogen compound(GO:0070458)
0.1 0.3 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 2.4 GO:0035640 exploration behavior(GO:0035640)
0.1 0.3 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 1.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.4 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.4 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.4 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.3 GO:0001964 startle response(GO:0001964)
0.1 0.9 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.2 GO:0071899 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 1.0 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.1 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 0.3 GO:2000672 response to sorbitol(GO:0072708) cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.2 GO:0040009 regulation of growth rate(GO:0040009)
0.1 0.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.9 GO:0021756 striatum development(GO:0021756)
0.1 0.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.3 GO:0015692 lead ion transport(GO:0015692)
0.1 1.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 1.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.2 GO:0061346 chemoattraction of serotonergic neuron axon(GO:0036517) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 1.1 GO:0015669 gas transport(GO:0015669)
0.0 0.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 1.0 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 2.5 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.4 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 1.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 1.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.6 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.3 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.9 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.3 GO:0006311 meiotic gene conversion(GO:0006311)
0.0 0.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 1.3 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 7.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.5 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.3 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.2 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0051262 protein tetramerization(GO:0051262)
0.0 2.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.4 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.5 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.4 GO:0043589 skin morphogenesis(GO:0043589)
0.0 1.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.9 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 6.7 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.4 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 1.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 1.0 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.9 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.4 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 1.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.9 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 1.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.0 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.4 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.2 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.2 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.4 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.7 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.0 0.1 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:0060084 micturition(GO:0060073) synaptic transmission involved in micturition(GO:0060084)
0.0 0.4 GO:0034349 glial cell apoptotic process(GO:0034349)
0.0 0.2 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 1.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.3 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 1.6 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 1.2 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.1 GO:1902462 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.2 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.2 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.7 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0006813 potassium ion transport(GO:0006813)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.0 1.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.2 GO:0098792 xenophagy(GO:0098792)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.0 GO:0090194 negative regulation of glomerular mesangial cell proliferation(GO:0072125) posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) negative regulation of glomerulus development(GO:0090194)
0.0 0.1 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.2 GO:0097484 dendrite extension(GO:0097484)
0.0 0.0 GO:0072183 negative regulation by virus of viral protein levels in host cell(GO:0046725) kidney mesenchymal cell proliferation(GO:0072135) metanephric mesenchymal cell proliferation involved in metanephros development(GO:0072136) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.0 0.1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.6 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.3 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0098855 HCN channel complex(GO:0098855)
0.5 9.5 GO:0031209 SCAR complex(GO:0031209)
0.5 7.9 GO:0044327 dendritic spine head(GO:0044327)
0.4 2.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.4 6.1 GO:0043083 synaptic cleft(GO:0043083)
0.4 1.5 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.4 3.5 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.3 5.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 1.1 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3 0.8 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.2 1.6 GO:0044326 dendritic spine neck(GO:0044326)
0.2 1.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 5.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 1.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 2.0 GO:0005955 calcineurin complex(GO:0005955)
0.2 3.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 0.6 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.2 0.6 GO:1990742 microvesicle(GO:1990742)
0.2 5.2 GO:0043194 axon initial segment(GO:0043194)
0.2 0.5 GO:0044305 calyx of Held(GO:0044305)
0.1 17.1 GO:0043195 terminal bouton(GO:0043195)
0.1 8.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 4.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.4 GO:0002139 stereocilia coupling link(GO:0002139)
0.1 1.5 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 1.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.1 1.2 GO:0061574 ASAP complex(GO:0061574)
0.1 0.9 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 2.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.8 GO:0005883 neurofilament(GO:0005883)
0.1 3.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 2.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.6 GO:0097513 myosin II filament(GO:0097513)
0.1 2.0 GO:0034709 methylosome(GO:0034709)
0.1 0.7 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.3 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.4 GO:0043293 apoptosome(GO:0043293)
0.1 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.3 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 2.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.1 GO:0044308 axonal spine(GO:0044308)
0.1 2.2 GO:0071565 nBAF complex(GO:0071565)
0.1 0.9 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 5.5 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.4 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 2.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 9.2 GO:0034705 potassium channel complex(GO:0034705)
0.1 0.9 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.1 11.2 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.1 5.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 8.2 GO:0043204 perikaryon(GO:0043204)
0.1 2.0 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.1 GO:0000806 Y chromosome(GO:0000806)
0.0 0.5 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.4 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.4 GO:0005605 basal lamina(GO:0005605)
0.0 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 1.3 GO:0043679 axon terminus(GO:0043679)
0.0 1.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0035859 Seh1-associated complex(GO:0035859) Iml1 complex(GO:1990130)
0.0 0.6 GO:0097227 sperm annulus(GO:0097227)
0.0 0.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0008091 spectrin(GO:0008091)
0.0 0.7 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.9 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 9.1 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 1.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.0 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 1.0 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 1.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 2.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.9 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.2 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 1.0 GO:0005901 caveola(GO:0005901)
0.0 0.3 GO:0030018 Z disc(GO:0030018)
0.0 1.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0005770 late endosome(GO:0005770)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.9 GO:0005875 microtubule associated complex(GO:0005875)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.9 GO:0031751 D4 dopamine receptor binding(GO:0031751)
1.0 4.9 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.6 2.9 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.5 1.9 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.5 4.8 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.5 2.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 2.7 GO:0097001 ceramide binding(GO:0097001)
0.4 1.3 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.4 2.4 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.4 5.1 GO:0097016 L27 domain binding(GO:0097016)
0.4 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.4 1.1 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.3 2.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.3 1.0 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.3 1.3 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.3 3.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.3 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 8.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 2.6 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.3 2.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 1.0 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.2 0.7 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 2.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 8.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 2.8 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 0.5 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.2 1.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 0.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 1.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 0.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 0.6 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 4.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 1.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 0.9 GO:1902444 riboflavin binding(GO:1902444)
0.2 0.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 1.7 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 1.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 2.0 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.9 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960)
0.1 0.4 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.3 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 3.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.0 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 0.5 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.6 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.4 GO:0042731 PH domain binding(GO:0042731)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 3.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 3.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.4 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 1.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.0 GO:0070097 delta-catenin binding(GO:0070097)
0.1 2.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 6.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 7.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 4.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.1 10.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.3 GO:0004324 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 0.7 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.7 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 2.0 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.3 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 1.6 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 2.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.6 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.2 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 0.8 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 2.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.9 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 1.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 2.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 2.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.2 GO:0070546 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 1.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.8 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.4 GO:0052840 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.5 GO:0005534 galactose binding(GO:0005534)
0.1 0.4 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 1.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.3 GO:0010736 serum response element binding(GO:0010736)
0.1 2.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 3.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.4 GO:0008443 phosphofructokinase activity(GO:0008443)
0.1 0.3 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 2.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.8 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.4 GO:0030172 troponin C binding(GO:0030172)
0.0 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 3.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 2.8 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.7 GO:0015250 water channel activity(GO:0015250)
0.0 0.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 1.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.3 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 1.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.0 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 2.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 1.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.1 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.4 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 2.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 2.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.2 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 1.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 1.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 1.1 GO:0030552 cAMP binding(GO:0030552)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 2.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.0 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 2.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 5.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 1.0 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.7 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.4 GO:0030955 potassium ion binding(GO:0030955)
0.0 6.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.8 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0051117 ATPase binding(GO:0051117)
0.0 1.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 2.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 1.9 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 1.3 GO:0044325 ion channel binding(GO:0044325)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 14.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 10.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.5 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 3.2 PID AURORA A PATHWAY Aurora A signaling
0.0 1.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 1.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 ST ADRENERGIC Adrenergic Pathway
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 3.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 4.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 6.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 3.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 9.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 5.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.1 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 1.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 6.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.9 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.1 4.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 3.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 6.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 18.7 REACTOME NEURONAL SYSTEM Genes involved in Neuronal System
0.1 1.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 0.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 4.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.3 REACTOME KINESINS Genes involved in Kinesins
0.0 1.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 1.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 2.9 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 1.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins