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Illumina Body Map 2, young vs old

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Results for EMX1

Z-value: 0.03

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Transcription factors associated with EMX1

Gene Symbol Gene ID Gene Info
EMX1
ENSG00000135638.9 empty spiracles homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EMX1hg19_v2_chr2_+_73144604_731446540.441.3e-02Click!

Activity profile of EMX1 motif

Sorted Z-values of EMX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_111794446 9.64 ENST00000527950.1
CRYAB
crystallin, alpha B
chr1_+_160160283 7.43 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_+_160160346 7.08 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr13_+_110958124 6.15 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr9_-_95166976 5.76 ENST00000447356.1
OGN
osteoglycin
chr12_-_6233828 5.58 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr13_-_38172863 5.44 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr2_-_217560248 5.21 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr9_+_134165063 4.95 ENST00000372264.3
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr15_+_62853562 4.83 ENST00000561311.1
TLN2
talin 2
chr6_-_127780510 4.62 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr4_+_70796784 4.55 ENST00000246891.4
ENST00000444405.3
CSN1S1
casein alpha s1
chr9_-_95166884 4.55 ENST00000375561.5
OGN
osteoglycin
chr12_-_10978957 4.53 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chrX_-_18690210 4.40 ENST00000379984.3
RS1
retinoschisin 1
chr4_-_138453606 4.32 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr11_-_13517565 4.28 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr4_+_95916947 4.20 ENST00000506363.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_-_190446759 4.18 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr5_+_36608422 4.02 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_234667504 3.88 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr3_+_35685113 3.82 ENST00000419330.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr12_-_48164812 3.60 ENST00000549151.1
ENST00000548919.1
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr11_+_27015628 3.57 ENST00000318627.2
FIBIN
fin bud initiation factor homolog (zebrafish)
chrX_-_73051037 3.52 ENST00000445814.1
XIST
X inactive specific transcript (non-protein coding)
chr2_-_183387064 3.52 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr9_-_95166841 3.48 ENST00000262551.4
OGN
osteoglycin
chr11_-_102709441 3.46 ENST00000434103.1
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr11_-_26593649 3.44 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr14_+_93389425 3.42 ENST00000216492.5
ENST00000334654.4
CHGA
chromogranin A (parathyroid secretory protein 1)
chr3_+_2933893 3.37 ENST00000397459.2
CNTN4
contactin 4
chr10_-_71169031 3.36 ENST00000373307.1
TACR2
tachykinin receptor 2
chr11_-_26593779 3.27 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr10_-_93392811 3.25 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr4_+_119809984 3.24 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2
synaptopodin 2
chr11_-_26593677 3.16 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr4_-_186570679 3.14 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr4_-_138453559 3.14 ENST00000511115.1
PCDH18
protocadherin 18
chr18_-_24443151 3.13 ENST00000440832.3
AQP4
aquaporin 4
chr13_-_36050819 3.12 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr14_+_85994943 3.12 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr3_-_151034734 3.07 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr2_-_227050079 3.07 ENST00000423838.1
AC068138.1
AC068138.1
chr8_+_121137333 3.06 ENST00000309791.4
ENST00000297848.3
ENST00000247781.3
COL14A1
collagen, type XIV, alpha 1
chr4_-_186696425 3.06 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr12_+_26348246 3.00 ENST00000422622.2
SSPN
sarcospan
chr14_+_32798547 3.00 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chrX_-_13835147 2.99 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr14_+_32798462 2.98 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr1_+_159174701 2.95 ENST00000435307.1
DARC
Duffy blood group, atypical chemokine receptor
chr5_+_140557371 2.90 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr7_+_6655225 2.90 ENST00000457543.3
ZNF853
zinc finger protein 853
chr8_-_1922789 2.89 ENST00000521498.1
RP11-439C15.4
RP11-439C15.4
chr3_-_73610759 2.85 ENST00000466780.1
PDZRN3
PDZ domain containing ring finger 3
chr1_-_169396666 2.85 ENST00000456107.1
ENST00000367805.3
CCDC181
coiled-coil domain containing 181
chr15_-_94614049 2.84 ENST00000556447.1
ENST00000555772.1
CTD-3049M7.1
CTD-3049M7.1
chr5_+_140602904 2.83 ENST00000515856.2
ENST00000239449.4
PCDHB14
protocadherin beta 14
chr15_-_58571445 2.82 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chrX_-_110507098 2.81 ENST00000541758.1
CAPN6
calpain 6
chr20_+_42187682 2.80 ENST00000373092.3
ENST00000373077.1
SGK2
serum/glucocorticoid regulated kinase 2
chr5_+_53751445 2.80 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr5_+_147648393 2.80 ENST00000511106.1
ENST00000398450.4
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr11_-_101000445 2.77 ENST00000534013.1
PGR
progesterone receptor
chr11_-_118023490 2.76 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr12_-_91546926 2.70 ENST00000550758.1
DCN
decorin
chr22_-_32651326 2.69 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr15_+_63682335 2.69 ENST00000559379.1
ENST00000559821.1
RP11-321G12.1
RP11-321G12.1
chr1_-_112032284 2.66 ENST00000414219.1
ADORA3
adenosine A3 receptor
chr5_-_142077569 2.63 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
FGF1
fibroblast growth factor 1 (acidic)
chr18_+_32173276 2.61 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr2_-_166930131 2.58 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr16_-_29910853 2.58 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr17_+_11501748 2.58 ENST00000262442.4
ENST00000579828.1
DNAH9
dynein, axonemal, heavy chain 9
chr12_+_41831485 2.56 ENST00000539469.2
ENST00000298919.7
PDZRN4
PDZ domain containing ring finger 4
chr13_-_36788718 2.55 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr7_-_73038822 2.49 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLXIPL
MLX interacting protein-like
chr6_-_100912785 2.44 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr3_+_173116225 2.44 ENST00000457714.1
NLGN1
neuroligin 1
chr12_+_126107042 2.40 ENST00000535886.1
TMEM132B
transmembrane protein 132B
chr3_-_100565249 2.39 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr11_-_102576537 2.39 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr8_+_105235572 2.36 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr3_-_160823158 2.35 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr7_-_73038867 2.35 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLXIPL
MLX interacting protein-like
chr8_+_99956662 2.33 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2
odd-skipped related transciption factor 2
chr8_+_50824233 2.32 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr1_+_160370344 2.32 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr10_+_18629628 2.29 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_+_151646800 2.28 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr10_+_24738355 2.28 ENST00000307544.6
KIAA1217
KIAA1217
chr10_-_5046042 2.28 ENST00000421196.3
ENST00000455190.1
AKR1C2
aldo-keto reductase family 1, member C2
chr3_+_174158732 2.28 ENST00000434257.1
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr12_-_88974236 2.26 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr12_+_19358192 2.25 ENST00000538305.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chrX_+_54947229 2.25 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO
trophinin
chr5_-_9630463 2.24 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr11_-_129062093 2.24 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr19_-_12889226 2.23 ENST00000589400.1
ENST00000590839.1
ENST00000592079.1
HOOK2
hook microtubule-tethering protein 2
chr10_+_5005598 2.22 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr10_-_75351088 2.20 ENST00000451492.1
ENST00000413442.1
USP54
ubiquitin specific peptidase 54
chr7_-_82792215 2.19 ENST00000333891.9
ENST00000423517.2
PCLO
piccolo presynaptic cytomatrix protein
chr1_-_22222764 2.18 ENST00000439717.2
ENST00000412328.1
HSPG2
heparan sulfate proteoglycan 2
chr3_-_160823040 2.18 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr13_-_47471155 2.18 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chrX_+_99839799 2.17 ENST00000373031.4
TNMD
tenomodulin
chr12_+_78359999 2.14 ENST00000550503.1
NAV3
neuron navigator 3
chr10_-_21186144 2.13 ENST00000377119.1
NEBL
nebulette
chr8_+_98900132 2.12 ENST00000520016.1
MATN2
matrilin 2
chr20_+_42187608 2.12 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr3_+_158991025 2.12 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr1_-_205325850 2.11 ENST00000537168.1
KLHDC8A
kelch domain containing 8A
chr8_-_124553437 2.10 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr4_+_169418195 2.07 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr17_+_72426891 2.07 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr5_+_174151536 2.07 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr5_-_41794313 2.06 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr7_+_6713376 2.05 ENST00000399484.3
ENST00000544825.1
ENST00000401847.1
AC073343.1
Uncharacterized protein
chr8_-_17533838 2.04 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr3_+_155860751 2.03 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr4_-_168155169 2.03 ENST00000534949.1
ENST00000535728.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr12_-_16760195 2.02 ENST00000546281.1
ENST00000537757.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr9_+_12693336 2.01 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr12_+_26348429 2.01 ENST00000242729.2
SSPN
sarcospan
chr6_-_139613269 2.01 ENST00000358430.3
TXLNB
taxilin beta
chr8_+_70404996 2.00 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr4_-_87281196 1.99 ENST00000359221.3
MAPK10
mitogen-activated protein kinase 10
chr5_+_31193847 1.97 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr8_-_101661887 1.97 ENST00000311812.2
SNX31
sorting nexin 31
chr12_+_41136144 1.96 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr4_-_87281224 1.95 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr15_-_37393406 1.94 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr2_+_149974684 1.94 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chr18_-_3220106 1.93 ENST00000356443.4
ENST00000400569.3
MYOM1
myomesin 1
chr4_+_88896819 1.92 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr3_+_156799587 1.92 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr2_-_179672142 1.90 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN
titin
chr1_-_242162375 1.90 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr11_-_128894053 1.90 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr4_-_186696561 1.89 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr21_+_33671160 1.87 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr3_-_164796269 1.86 ENST00000264382.3
SI
sucrase-isomaltase (alpha-glucosidase)
chr7_-_107642348 1.85 ENST00000393561.1
LAMB1
laminin, beta 1
chr6_-_46293378 1.84 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr8_+_99956759 1.84 ENST00000522510.1
ENST00000457907.2
OSR2
odd-skipped related transciption factor 2
chr15_+_76016293 1.84 ENST00000332145.2
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr20_+_60174827 1.83 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr13_+_36050881 1.83 ENST00000537702.1
NBEA
neurobeachin
chr3_+_35722487 1.83 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr3_+_111717511 1.82 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr8_+_24298531 1.81 ENST00000175238.6
ADAM7
ADAM metallopeptidase domain 7
chr6_+_153552455 1.78 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr2_-_203735586 1.78 ENST00000454326.1
ENST00000432273.1
ENST00000450143.1
ENST00000411681.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr12_-_85306562 1.77 ENST00000551612.1
ENST00000450363.3
ENST00000552192.1
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr14_-_23652849 1.77 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr1_+_86934526 1.74 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr7_-_83278322 1.74 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr11_+_65554493 1.71 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr18_-_33709268 1.71 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr12_+_32638897 1.69 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr14_+_101359265 1.69 ENST00000599197.1
AL117190.3
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr1_-_169396646 1.68 ENST00000367806.3
CCDC181
coiled-coil domain containing 181
chr5_-_159846066 1.68 ENST00000519349.1
ENST00000520664.1
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr8_+_39972170 1.68 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr12_-_23737534 1.67 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr4_+_41614909 1.67 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr4_-_186696515 1.67 ENST00000456596.1
ENST00000414724.1
SORBS2
sorbin and SH3 domain containing 2
chr7_-_107883678 1.66 ENST00000417701.1
NRCAM
neuronal cell adhesion molecule
chr3_+_130745688 1.66 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NEK11
NIMA-related kinase 11
chr2_-_152830441 1.66 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr6_+_76599809 1.65 ENST00000430435.1
MYO6
myosin VI
chr12_-_15815626 1.65 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr4_-_150736962 1.65 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1
RP11-526A4.1
chr5_-_96478466 1.65 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr18_+_616672 1.64 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr1_+_197237352 1.63 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
CRB1
crumbs homolog 1 (Drosophila)
chr4_-_10686475 1.63 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr4_+_110834033 1.63 ENST00000509793.1
ENST00000265171.5
EGF
epidermal growth factor
chr1_+_152943122 1.63 ENST00000328051.2
SPRR4
small proline-rich protein 4
chr11_+_107461804 1.62 ENST00000531234.1
ELMOD1
ELMO/CED-12 domain containing 1
chr3_-_180397256 1.62 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr15_+_48483736 1.62 ENST00000417307.2
ENST00000559641.1
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr2_+_7118755 1.61 ENST00000433456.1
RNF144A
ring finger protein 144A
chr12_-_22063787 1.61 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr5_-_16916624 1.60 ENST00000513882.1
MYO10
myosin X
chr17_+_48823975 1.59 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr1_+_35258592 1.59 ENST00000342280.4
ENST00000450137.1
GJA4
gap junction protein, alpha 4, 37kDa
chr5_-_115890554 1.57 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr8_+_92261516 1.57 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr12_+_54378923 1.57 ENST00000303460.4
HOXC10
homeobox C10
chr10_-_128110441 1.57 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chr12_-_25348007 1.57 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr6_-_49681235 1.57 ENST00000339139.4
CRISP2
cysteine-rich secretory protein 2
chrX_-_46187069 1.56 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr14_+_52164820 1.56 ENST00000554167.1
FRMD6
FERM domain containing 6
chr5_-_147286065 1.56 ENST00000318315.4
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr1_-_67266939 1.55 ENST00000304526.2
INSL5
insulin-like 5
chr4_+_169418255 1.55 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr12_+_6419877 1.55 ENST00000536531.1
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr19_+_58570605 1.55 ENST00000359978.6
ENST00000401053.4
ENST00000439855.2
ENST00000313434.5
ENST00000511556.1
ENST00000506786.1
ZNF135
zinc finger protein 135
chr1_-_205325698 1.53 ENST00000460687.1
KLHDC8A
kelch domain containing 8A

Network of associatons between targets according to the STRING database.

First level regulatory network of EMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
1.4 4.3 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
1.1 3.4 GO:1901899 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
1.1 3.4 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
1.1 14.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.1 4.4 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.9 5.4 GO:0032571 response to vitamin K(GO:0032571) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523)
0.8 5.6 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.8 2.3 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.8 2.3 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.7 6.0 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.7 2.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.7 3.6 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.7 2.8 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.7 2.1 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.7 3.4 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685) operant conditioning(GO:0035106)
0.6 2.4 GO:0097115 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.6 4.2 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.6 13.1 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.6 4.5 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.5 5.8 GO:0070777 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.5 3.0 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.5 1.9 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.5 1.9 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.5 2.8 GO:0060467 negative regulation of fertilization(GO:0060467)
0.4 1.7 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.4 4.8 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.4 1.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.4 9.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.4 1.9 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.4 2.9 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 1.5 GO:1902725 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.4 1.5 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.4 1.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.3 1.0 GO:2001222 regulation of neuron migration(GO:2001222)
0.3 3.3 GO:0015820 leucine transport(GO:0015820)
0.3 2.6 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.3 1.0 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.3 1.6 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.3 2.2 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.3 5.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.3 1.5 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.3 0.9 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.3 2.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.3 2.8 GO:0035799 ureter maturation(GO:0035799)
0.3 3.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.3 2.8 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.3 1.9 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.3 4.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 6.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.3 1.0 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.3 2.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.3 1.0 GO:0035425 autocrine signaling(GO:0035425)
0.2 1.5 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 3.5 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.2 1.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 1.4 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.2 3.6 GO:0086027 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.2 6.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 0.7 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 10.1 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 0.9 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.2 0.7 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.2 5.9 GO:0003334 keratinocyte development(GO:0003334)
0.2 0.6 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.2 1.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 1.1 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 1.5 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 1.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 8.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 2.0 GO:0051013 microtubule severing(GO:0051013)
0.2 2.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.2 2.0 GO:0060685 regulation of prostatic bud formation(GO:0060685) negative regulation of prostatic bud formation(GO:0060686)
0.2 1.0 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 1.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.2 1.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 1.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.2 2.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 2.5 GO:0032596 protein transport into membrane raft(GO:0032596)
0.2 3.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.6 GO:0003383 apical constriction(GO:0003383)
0.2 0.8 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 4.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 1.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.2 0.9 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.2 0.8 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.2 1.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 1.4 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.2 0.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 3.0 GO:0019532 oxalate transport(GO:0019532)
0.2 2.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 4.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 2.1 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 1.9 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 1.3 GO:0030242 pexophagy(GO:0030242)
0.1 2.0 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 2.0 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.7 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.7 GO:1904640 response to methionine(GO:1904640)
0.1 1.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) regulation of protein autoubiquitination(GO:1902498)
0.1 0.4 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 1.7 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.9 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 3.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.1 0.8 GO:0072501 cellular divalent inorganic anion homeostasis(GO:0072501)
0.1 0.6 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 1.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 1.0 GO:2001023 regulation of response to drug(GO:2001023)
0.1 1.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.6 GO:0006836 neurotransmitter transport(GO:0006836)
0.1 1.4 GO:0016198 axon choice point recognition(GO:0016198)
0.1 1.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 2.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 1.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 3.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 1.6 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 1.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 0.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 1.5 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.9 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 1.1 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.1 10.1 GO:0016266 O-glycan processing(GO:0016266)
0.1 2.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 19.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.9 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 1.9 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 1.4 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 1.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.6 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 1.7 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 2.0 GO:0043584 nose development(GO:0043584)
0.1 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 3.3 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.5 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.9 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.7 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 2.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.3 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 0.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.4 GO:0015692 lead ion transport(GO:0015692)
0.1 1.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 1.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.9 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 1.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 2.7 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.3 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 4.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.4 GO:0061107 seminal vesicle development(GO:0061107)
0.1 2.9 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 3.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 1.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.5 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.4 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 1.2 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.1 3.0 GO:0010107 potassium ion import(GO:0010107)
0.1 1.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 2.4 GO:0097352 autophagosome maturation(GO:0097352)
0.1 0.3 GO:1904383 response to sodium phosphate(GO:1904383) response to insulin-like growth factor stimulus(GO:1990418)
0.1 0.3 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 2.0 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 1.7 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.8 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.8 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.5 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 2.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 3.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 3.5 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.3 GO:0007498 mesoderm development(GO:0007498)
0.0 1.8 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 1.4 GO:0019751 polyol metabolic process(GO:0019751)
0.0 0.3 GO:0099627 neurotransmitter receptor internalization(GO:0099590) neurotransmitter receptor cycle(GO:0099627)
0.0 0.4 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 1.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.9 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 11.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 3.0 GO:0035418 protein localization to synapse(GO:0035418)
0.0 2.1 GO:0008347 glial cell migration(GO:0008347)
0.0 1.1 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 2.1 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.4 GO:0051642 centrosome localization(GO:0051642)
0.0 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 8.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.6 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 3.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.9 GO:0043586 tongue development(GO:0043586)
0.0 0.3 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 1.8 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 1.0 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 1.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 2.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.4 GO:0051451 myoblast migration(GO:0051451)
0.0 1.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 1.2 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.5 GO:2000169 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0 0.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.9 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 2.1 GO:0003341 cilium movement(GO:0003341)
0.0 2.9 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.7 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 4.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.7 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 1.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 1.3 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 3.4 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.9 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.7 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 2.5 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.1 GO:1901631 postsynaptic membrane assembly(GO:0097104) positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 1.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.1 GO:0009408 response to heat(GO:0009408)
0.0 2.3 GO:0001657 ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.9 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 2.3 GO:0001523 retinoid metabolic process(GO:0001523)
0.0 0.8 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 1.2 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.5 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.0 0.7 GO:0001701 in utero embryonic development(GO:0001701)
0.0 1.2 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 2.0 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.6 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 1.5 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.6 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 1.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.5 GO:0030574 collagen catabolic process(GO:0030574)
0.0 1.9 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 2.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.8 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 2.5 GO:0006936 muscle contraction(GO:0006936)
0.0 0.3 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.5 GO:0090277 positive regulation of peptide hormone secretion(GO:0090277)
0.0 0.5 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0030324 respiratory tube development(GO:0030323) lung development(GO:0030324)
0.0 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 4.4 GO:0019898 extrinsic component of membrane(GO:0019898)
1.8 14.5 GO:0014802 terminal cisterna(GO:0014802)
0.7 2.8 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.7 6.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.6 1.9 GO:0043257 laminin-8 complex(GO:0043257)
0.6 3.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.6 2.3 GO:0060187 cell pole(GO:0060187)
0.6 9.6 GO:0097512 cardiac myofibril(GO:0097512)
0.6 4.5 GO:0002177 manchette(GO:0002177)
0.5 5.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.4 1.5 GO:0097224 sperm connecting piece(GO:0097224)
0.4 3.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.4 1.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.4 5.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.4 6.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.3 8.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 1.6 GO:0005879 axonemal microtubule(GO:0005879)
0.3 2.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 0.9 GO:0036457 keratohyalin granule(GO:0036457)
0.3 2.3 GO:0070852 cell body fiber(GO:0070852)
0.3 2.0 GO:1990635 proximal dendrite(GO:1990635)
0.2 2.4 GO:0032982 myosin filament(GO:0032982)
0.2 2.3 GO:0016013 syntrophin complex(GO:0016013)
0.2 30.6 GO:0005796 Golgi lumen(GO:0005796)
0.2 2.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 2.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 4.0 GO:0032433 filopodium tip(GO:0032433)
0.1 5.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 2.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.6 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.8 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 7.9 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.9 GO:0070695 FHF complex(GO:0070695)
0.1 27.7 GO:0030018 Z disc(GO:0030018)
0.1 1.0 GO:0071547 piP-body(GO:0071547)
0.1 0.6 GO:0097441 basilar dendrite(GO:0097441)
0.1 1.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 2.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 1.7 GO:0043194 axon initial segment(GO:0043194)
0.1 0.4 GO:0036026 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 1.9 GO:0034709 methylosome(GO:0034709)
0.1 1.4 GO:0005869 dynactin complex(GO:0005869)
0.1 1.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 1.3 GO:0097433 dense body(GO:0097433)
0.1 2.4 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 3.0 GO:0005921 gap junction(GO:0005921)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 2.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 1.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 1.0 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.6 GO:0000801 central element(GO:0000801)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.4 GO:0032437 cuticular plate(GO:0032437)
0.1 2.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 3.5 GO:0030286 dynein complex(GO:0030286)
0.1 5.0 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.1 8.3 GO:0030175 filopodium(GO:0030175)
0.0 1.1 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.9 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.0 10.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.6 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 1.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.0 2.6 GO:0001533 cornified envelope(GO:0001533)
0.0 4.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.8 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.4 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.6 GO:0042583 chromaffin granule(GO:0042583)
0.0 2.3 GO:0099568 cytoplasmic region(GO:0099568)
0.0 0.7 GO:0000800 lateral element(GO:0000800)
0.0 0.4 GO:0001939 female pronucleus(GO:0001939) male pronucleus(GO:0001940) transcription factor TFIIA complex(GO:0005672)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.0 2.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 13.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.0 GO:0042383 sarcolemma(GO:0042383)
0.0 0.9 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.8 GO:0071565 nBAF complex(GO:0071565)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)
0.0 1.5 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.6 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 1.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.0 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 13.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 1.3 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 1.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 3.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.2 GO:0090543 ESCRT III complex(GO:0000815) Flemming body(GO:0090543)
0.0 2.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.1 GO:0043209 myelin sheath(GO:0043209)
0.0 1.7 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
1.1 3.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.9 2.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.8 3.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.8 3.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.7 3.4 GO:0004995 tachykinin receptor activity(GO:0004995)
0.6 4.5 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.6 1.9 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.6 5.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.6 2.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.6 1.7 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.5 1.6 GO:0031862 prostanoid receptor binding(GO:0031862)
0.5 2.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.5 3.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.5 1.5 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.5 5.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.5 1.9 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.5 1.4 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.4 2.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.4 3.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.4 8.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 8.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.4 7.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.4 1.5 GO:1990254 keratin filament binding(GO:1990254)
0.4 5.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 1.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.3 12.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.3 3.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 2.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 9.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 2.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.3 2.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.3 0.9 GO:0033149 FFAT motif binding(GO:0033149)
0.3 1.4 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.2 1.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 10.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.7 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2 0.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 1.9 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.2 1.9 GO:0032027 myosin light chain binding(GO:0032027)
0.2 2.9 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 4.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 3.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 3.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 2.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 2.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 0.5 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.2 6.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 1.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 0.9 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.2 2.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 3.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 4.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 3.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 2.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.6 GO:0015563 thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.1 1.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.8 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.9 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.7 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 6.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 4.7 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.9 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.9 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 2.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 2.6 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.7 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 12.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.5 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 1.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 1.7 GO:0005522 profilin binding(GO:0005522)
0.1 2.1 GO:0031005 filamin binding(GO:0031005)
0.1 2.0 GO:0070402 NADPH binding(GO:0070402)
0.1 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.4 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 2.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.3 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1 1.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.9 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 2.1 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 10.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.4 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 2.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.1 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 1.5 GO:0035198 miRNA binding(GO:0035198)
0.0 6.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 2.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.4 GO:0000146 microfilament motor activity(GO:0000146)
0.0 2.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.1 GO:0048037 cofactor binding(GO:0048037)
0.0 11.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 12.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 1.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 2.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.4 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 1.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 11.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 3.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.8 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 1.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 4.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 3.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 3.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162) microtubule plus-end binding(GO:0051010)
0.0 1.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 2.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 23.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.0 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 7.1 GO:0003779 actin binding(GO:0003779)
0.0 0.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 8.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.8 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.0 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 20.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 9.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 7.8 PID BMP PATHWAY BMP receptor signaling
0.1 3.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 2.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 25.5 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1 2.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 5.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 6.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 4.7 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 2.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.4 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 3.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 13.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 5.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 9.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 2.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 10.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.9 REACTOME OPSINS Genes involved in Opsins
0.1 2.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 3.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.9 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 3.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 5.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 3.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 4.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 4.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 5.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 7.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 4.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 2.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.6 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 1.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.6 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.1 2.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 5.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 3.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 3.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 3.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 4.3 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 3.6 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.4 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 3.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 10.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 2.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 2.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 4.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 2.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.2 REACTOME SIGNALING BY FGFR MUTANTS Genes involved in Signaling by FGFR mutants
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction