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Illumina Body Map 2, young vs old

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Results for EMX2

Z-value: 0.15

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Transcription factors associated with EMX2

Gene Symbol Gene ID Gene Info
EMX2
ENSG00000170370.10 empty spiracles homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EMX2hg19_v2_chr10_+_119301928_1193019550.281.2e-01Click!

Activity profile of EMX2 motif

Sorted Z-values of EMX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_54466179 2.10 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr6_+_13272904 1.61 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr4_-_168155169 1.35 ENST00000534949.1
ENST00000535728.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr12_+_101988774 1.27 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr1_-_67266939 1.25 ENST00000304526.2
INSL5
insulin-like 5
chr12_+_101988627 1.24 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr6_+_72926145 1.11 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr4_-_120243545 1.10 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr18_-_24445664 1.07 ENST00000578776.1
AQP4
aquaporin 4
chr1_-_120935894 1.03 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr1_+_149754227 1.02 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr15_+_84115868 0.97 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr5_+_36608280 0.94 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_-_39093672 0.93 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr11_-_107729504 0.92 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr11_-_26593677 0.90 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr12_-_123201337 0.89 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr18_-_24445729 0.88 ENST00000383168.4
AQP4
aquaporin 4
chr8_-_87242589 0.87 ENST00000419776.2
ENST00000297524.3
SLC7A13
solute carrier family 7 (anionic amino acid transporter), member 13
chr11_-_107729287 0.87 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr14_-_47351391 0.86 ENST00000399222.3
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr11_-_40315640 0.86 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr9_-_28670283 0.84 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr4_-_122854612 0.83 ENST00000264811.5
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr11_-_26593779 0.83 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr18_+_616672 0.83 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr20_+_9494987 0.82 ENST00000427562.2
ENST00000246070.2
LAMP5
lysosomal-associated membrane protein family, member 5
chr4_-_100356551 0.80 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_+_111773349 0.79 ENST00000533831.2
CHI3L2
chitinase 3-like 2
chr14_-_80697396 0.77 ENST00000557010.1
DIO2
deiodinase, iodothyronine, type II
chr3_+_130745688 0.77 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NEK11
NIMA-related kinase 11
chr6_+_26204825 0.77 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr22_+_39966758 0.77 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
CACNA1I
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr2_-_209051727 0.76 ENST00000453017.1
ENST00000423952.2
C2orf80
chromosome 2 open reading frame 80
chr7_+_54398390 0.75 ENST00000458615.1
ENST00000426205.1
RP11-436F9.1
RP11-436F9.1
chr11_-_26593649 0.75 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr20_+_33563206 0.75 ENST00000262873.7
MYH7B
myosin, heavy chain 7B, cardiac muscle, beta
chr5_+_161495038 0.75 ENST00000393933.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chrX_+_106765680 0.71 ENST00000276185.4
FRMPD3
FERM and PDZ domain containing 3
chr4_-_112993808 0.69 ENST00000511219.1
RP11-269F21.3
RP11-269F21.3
chr1_+_87012922 0.68 ENST00000263723.5
CLCA4
chloride channel accessory 4
chr10_-_21186144 0.68 ENST00000377119.1
NEBL
nebulette
chrX_+_135730373 0.67 ENST00000370628.2
CD40LG
CD40 ligand
chr5_-_74162739 0.66 ENST00000513277.1
FAM169A
family with sequence similarity 169, member A
chr5_-_111093167 0.65 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr3_+_63638339 0.65 ENST00000343837.3
ENST00000469440.1
SNTN
sentan, cilia apical structure protein
chr12_-_86650077 0.65 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr17_-_57158523 0.64 ENST00000581468.1
TRIM37
tripartite motif containing 37
chr12_-_86650045 0.64 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr12_-_86650154 0.64 ENST00000552435.2
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_+_87012753 0.64 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr17_+_61151306 0.62 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr11_-_107729887 0.61 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr12_-_123187890 0.60 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr18_+_32290218 0.60 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA
dystrobrevin, alpha
chr4_-_109541539 0.59 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr12_+_10163231 0.59 ENST00000396502.1
ENST00000338896.5
CLEC12B
C-type lectin domain family 12, member B
chr1_+_84609944 0.58 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_+_140981456 0.58 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chrX_+_135730297 0.58 ENST00000370629.2
CD40LG
CD40 ligand
chr9_+_71986182 0.57 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr3_-_181160240 0.57 ENST00000460993.1
RP11-275H4.1
RP11-275H4.1
chr1_+_66820058 0.57 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr6_-_46048116 0.56 ENST00000185206.6
CLIC5
chloride intracellular channel 5
chr4_-_109541610 0.56 ENST00000510212.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr1_+_192778161 0.56 ENST00000235382.5
RGS2
regulator of G-protein signaling 2, 24kDa
chr2_+_39117010 0.54 ENST00000409978.1
ARHGEF33
Rho guanine nucleotide exchange factor (GEF) 33
chr8_+_104892639 0.53 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr4_+_139230865 0.53 ENST00000502757.1
ENST00000507145.1
ENST00000515282.1
ENST00000510736.1
LINC00499
long intergenic non-protein coding RNA 499
chr3_-_131756559 0.53 ENST00000505957.1
CPNE4
copine IV
chr16_-_74330612 0.53 ENST00000569389.1
ENST00000562888.1
AC009120.4
AC009120.4
chr8_+_35649365 0.52 ENST00000437887.1
AC012215.1
Uncharacterized protein
chrX_+_144908928 0.52 ENST00000408967.2
TMEM257
transmembrane protein 257
chr14_+_85994943 0.52 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr4_-_89205879 0.51 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr5_-_111093081 0.51 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr14_+_22580233 0.51 ENST00000390454.2
TRAV25
T cell receptor alpha variable 25
chrX_-_72434628 0.51 ENST00000536638.1
ENST00000373517.3
NAP1L2
nucleosome assembly protein 1-like 2
chr11_-_128894053 0.51 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr11_+_12308447 0.50 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr16_-_1538765 0.50 ENST00000447419.2
ENST00000440447.2
PTX4
pentraxin 4, long
chr2_+_28718921 0.50 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
PLB1
phospholipase B1
chrX_+_36254051 0.50 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chrX_+_18443703 0.50 ENST00000379996.3
CDKL5
cyclin-dependent kinase-like 5
chr20_+_15177480 0.50 ENST00000402914.1
MACROD2
MACRO domain containing 2
chr1_+_36549676 0.50 ENST00000207457.3
TEKT2
tektin 2 (testicular)
chr1_-_190446759 0.49 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr3_-_151047327 0.49 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr6_-_24645956 0.48 ENST00000543707.1
KIAA0319
KIAA0319
chr11_+_119019722 0.48 ENST00000307417.3
ABCG4
ATP-binding cassette, sub-family G (WHITE), member 4
chr4_+_89206076 0.48 ENST00000500009.2
RP11-10L7.1
RP11-10L7.1
chr10_+_91092241 0.46 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr7_-_17598506 0.46 ENST00000451792.1
AC017060.1
AC017060.1
chr9_+_12695702 0.46 ENST00000381136.2
TYRP1
tyrosinase-related protein 1
chr4_-_159956333 0.45 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr3_-_49466686 0.45 ENST00000273598.3
ENST00000436744.2
NICN1
nicolin 1
chr12_-_10282742 0.45 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr15_+_77713299 0.45 ENST00000559099.1
HMG20A
high mobility group 20A
chr5_-_137475071 0.45 ENST00000265191.2
NME5
NME/NM23 family member 5
chr11_-_83878041 0.45 ENST00000398299.1
DLG2
discs, large homolog 2 (Drosophila)
chr4_+_174818390 0.45 ENST00000509968.1
ENST00000512263.1
RP11-161D15.1
RP11-161D15.1
chr1_+_117544366 0.45 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr4_-_89205705 0.44 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr19_-_14945933 0.43 ENST00000322301.3
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr6_+_26251835 0.43 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr5_+_57787254 0.43 ENST00000502276.1
ENST00000396776.2
ENST00000511930.1
GAPT
GRB2-binding adaptor protein, transmembrane
chr15_-_41166414 0.43 ENST00000220507.4
RHOV
ras homolog family member V
chr12_-_10282681 0.42 ENST00000533022.1
CLEC7A
C-type lectin domain family 7, member A
chr5_-_11588907 0.42 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr2_-_85625857 0.42 ENST00000453973.1
CAPG
capping protein (actin filament), gelsolin-like
chr15_+_77713222 0.42 ENST00000558176.1
HMG20A
high mobility group 20A
chr1_-_173174681 0.42 ENST00000367718.1
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr14_+_22675388 0.42 ENST00000390461.2
TRAV34
T cell receptor alpha variable 34
chr6_-_109761707 0.41 ENST00000520723.1
ENST00000518648.1
ENST00000417394.2
PPIL6
peptidylprolyl isomerase (cyclophilin)-like 6
chr12_-_68553512 0.41 ENST00000229135.3
IFNG
interferon, gamma
chr19_+_58144529 0.40 ENST00000347302.3
ENST00000254182.7
ENST00000391703.3
ENST00000541801.1
ENST00000299871.5
ENST00000544273.1
ZNF211
zinc finger protein 211
chr2_-_142888573 0.40 ENST00000434794.1
LRP1B
low density lipoprotein receptor-related protein 1B
chr5_-_111312622 0.40 ENST00000395634.3
NREP
neuronal regeneration related protein
chr14_+_22670455 0.40 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr4_-_74864386 0.40 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr9_-_21368075 0.39 ENST00000449498.1
IFNA13
interferon, alpha 13
chr8_-_38008783 0.39 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr6_+_12718497 0.39 ENST00000379348.2
PHACTR1
phosphatase and actin regulator 1
chr7_+_129906660 0.38 ENST00000222481.4
CPA2
carboxypeptidase A2 (pancreatic)
chr2_+_120687335 0.38 ENST00000544261.1
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr14_-_47812321 0.38 ENST00000357362.3
ENST00000486952.2
ENST00000426342.1
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr2_+_105050794 0.38 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr5_+_136070614 0.38 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr16_-_21663919 0.38 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr1_+_15668240 0.38 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr11_+_45376922 0.38 ENST00000524410.1
ENST00000524488.1
ENST00000524565.1
RP11-430H10.1
RP11-430H10.1
chr9_+_71944241 0.37 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr18_+_29769978 0.36 ENST00000269202.6
ENST00000581447.1
MEP1B
meprin A, beta
chr9_-_125391852 0.36 ENST00000304833.3
OR1B1
olfactory receptor, family 1, subfamily B, member 1
chr18_-_61311485 0.36 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr21_+_35552978 0.36 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310
long intergenic non-protein coding RNA 310
chrX_+_36053908 0.36 ENST00000378660.2
CHDC2
calponin homology domain containing 2
chr16_-_21663950 0.36 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr7_+_123241908 0.36 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15
ankyrin repeat and SOCS box containing 15
chr2_+_13677795 0.36 ENST00000434509.1
AC092635.1
AC092635.1
chr10_-_75226166 0.36 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr1_+_234765057 0.36 ENST00000429269.1
LINC00184
long intergenic non-protein coding RNA 184
chr7_-_16505440 0.35 ENST00000307068.4
SOSTDC1
sclerostin domain containing 1
chr18_-_33702078 0.35 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr22_+_50981079 0.35 ENST00000609268.1
CTA-384D8.34
CTA-384D8.34
chr2_-_14541060 0.35 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr1_+_152956549 0.34 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr17_-_26301249 0.34 ENST00000567574.1
RP11-218F4.1
RP11-218F4.1
chr11_-_104905840 0.34 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr19_-_44388116 0.34 ENST00000587539.1
ZNF404
zinc finger protein 404
chr11_+_108094786 0.34 ENST00000601453.1
ATM
ataxia telangiectasia mutated
chr6_-_110501126 0.34 ENST00000368938.1
WASF1
WAS protein family, member 1
chr5_-_88119580 0.34 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr15_-_75748143 0.33 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3A
SIN3 transcription regulator family member A
chr11_+_10476851 0.33 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr12_+_93096619 0.33 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr12_-_10282836 0.32 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr2_+_157330081 0.32 ENST00000409674.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr11_+_47293795 0.31 ENST00000422579.1
MADD
MAP-kinase activating death domain
chr14_+_23709555 0.31 ENST00000430154.2
C14orf164
chromosome 14 open reading frame 164
chr14_+_45464658 0.31 ENST00000555874.1
FAM179B
family with sequence similarity 179, member B
chr12_+_78359999 0.31 ENST00000550503.1
NAV3
neuron navigator 3
chr1_-_20250110 0.31 ENST00000375116.3
PLA2G2E
phospholipase A2, group IIE
chr15_-_101137121 0.31 ENST00000560934.1
LINS
lines homolog (Drosophila)
chr1_+_248185250 0.31 ENST00000355281.1
OR2L5
olfactory receptor, family 2, subfamily L, member 5
chr11_+_92085262 0.31 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr19_+_14693888 0.31 ENST00000547437.1
ENST00000397439.2
ENST00000417570.1
CLEC17A
C-type lectin domain family 17, member A
chr11_-_104972158 0.30 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr12_-_49581152 0.30 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr9_+_75766763 0.30 ENST00000456643.1
ENST00000415424.1
ANXA1
annexin A1
chr3_-_155011483 0.30 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr22_-_33454354 0.30 ENST00000358763.2
SYN3
synapsin III
chr3_+_190917023 0.30 ENST00000445281.1
OSTN
osteocrin
chr21_-_19858196 0.30 ENST00000422787.1
TMPRSS15
transmembrane protease, serine 15
chr11_-_46141338 0.29 ENST00000529782.1
ENST00000532010.1
ENST00000525438.1
ENST00000533757.1
ENST00000527782.1
PHF21A
PHD finger protein 21A
chr8_+_24151553 0.29 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr19_-_37697976 0.29 ENST00000588873.1
CTC-454I21.3
Uncharacterized protein; Zinc finger protein 585B
chr3_+_111393501 0.29 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr6_-_112081113 0.29 ENST00000517419.1
FYN
FYN oncogene related to SRC, FGR, YES
chr9_+_125133315 0.29 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr6_+_72922505 0.29 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr6_-_33041378 0.29 ENST00000428995.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr2_-_170550842 0.29 ENST00000421028.1
CCDC173
coiled-coil domain containing 173
chrX_-_9734038 0.28 ENST00000431126.1
GPR143
G protein-coupled receptor 143
chr19_+_42300548 0.28 ENST00000344550.4
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr16_+_18995249 0.28 ENST00000569532.1
ENST00000304381.5
TMC7
transmembrane channel-like 7
chr11_-_104916034 0.28 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16
caspase recruitment domain family, member 16
chr1_+_248097071 0.28 ENST00000318244.3
OR2AJ1
olfactory receptor, family 2, subfamily AJ, member 1
chr4_+_71248795 0.28 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chr19_-_43969796 0.28 ENST00000244333.3
LYPD3
LY6/PLAUR domain containing 3
chr19_-_36822551 0.28 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chr12_+_93096759 0.28 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr10_+_122610853 0.28 ENST00000604585.1
WDR11
WD repeat domain 11
chr9_+_125132803 0.28 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_86848760 0.27 ENST00000460698.2
ODF2L
outer dense fiber of sperm tails 2-like
chr13_-_20110902 0.27 ENST00000390680.2
ENST00000382977.4
ENST00000382975.4
ENST00000457266.2
TPTE2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr2_+_7073174 0.27 ENST00000416587.1
RNF144A
ring finger protein 144A
chr5_-_111092930 0.27 ENST00000257435.7
NREP
neuronal regeneration related protein
chr11_+_122709200 0.27 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr1_+_248201474 0.27 ENST00000366479.2
OR2L2
olfactory receptor, family 2, subfamily L, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of EMX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 1.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 0.6 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.9 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.5 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.2 0.5 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 0.4 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.4 GO:2000309 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309)
0.1 0.4 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 2.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.6 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.5 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.8 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.4 GO:0018963 insecticide metabolic process(GO:0017143) phthalate metabolic process(GO:0018963)
0.1 2.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.3 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.5 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 2.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.5 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.6 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
0.1 0.3 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.3 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.3 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.2 GO:1904647 response to rotenone(GO:1904647)
0.1 0.3 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.1 0.6 GO:0097338 response to clozapine(GO:0097338)
0.1 0.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.6 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1 0.9 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.9 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.2 GO:0042414 epinephrine metabolic process(GO:0042414) cellular response to lead ion(GO:0071284)
0.0 0.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 1.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.2 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.0 0.2 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 1.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.7 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.1 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.5 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.9 GO:0071420 cellular response to histamine(GO:0071420)
0.0 1.4 GO:0006833 water transport(GO:0006833)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 1.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.3 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.8 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.4 GO:0046951 ketone body biosynthetic process(GO:0046951) cellular response to testosterone stimulus(GO:0071394)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.3 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678) swimming behavior(GO:0036269)
0.0 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0009615 response to virus(GO:0009615)
0.0 0.8 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 1.2 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0039519 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) modulation by virus of host autophagy(GO:0039519) suppression by virus of host autophagy(GO:0039521)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.2 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.2 GO:0035973 aggrephagy(GO:0035973)
0.0 0.5 GO:1903859 regulation of dendrite extension(GO:1903859)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 2.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.9 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.5 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 1.4 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 2.0 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.5 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 GO:0032982 myosin filament(GO:0032982)
0.1 0.6 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 0.8 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.5 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.2 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 3.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 1.0 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 2.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.0 2.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 2.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.8 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.0 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 1.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.3 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 2.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.5 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.2 0.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 0.5 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.2 0.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 1.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.5 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 1.9 GO:0015250 water channel activity(GO:0015250)
0.1 0.5 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 2.5 GO:0031432 titin binding(GO:0031432)
0.1 0.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.0 GO:0019864 IgG binding(GO:0019864)
0.1 0.3 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.3 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 1.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0042806 fucose binding(GO:0042806)
0.0 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.6 GO:0089720 caspase binding(GO:0089720)
0.0 0.7 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 1.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 2.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.6 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.9 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.0 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 1.5 GO:0019213 deacetylase activity(GO:0019213)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.0 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.9 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 1.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 2.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.4 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 2.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 4.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage