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Illumina Body Map 2, young vs old

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Results for EPAS1_BCL3

Z-value: 0.13

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Transcription factors associated with EPAS1_BCL3

Gene Symbol Gene ID Gene Info
ENSG00000116016.9 endothelial PAS domain protein 1
ENSG00000069399.8 BCL3 transcription coactivator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EPAS1hg19_v2_chr2_+_46524537_465245530.647.2e-05Click!
BCL3hg19_v2_chr19_+_45254529_45254578-0.364.2e-02Click!

Activity profile of EPAS1_BCL3 motif

Sorted Z-values of EPAS1_BCL3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_116163830 11.95 ENST00000333617.4
limbic system-associated membrane protein
chr19_+_35629702 8.57 ENST00000351325.4
FXYD domain containing ion transport regulator 1
chr7_+_136553370 7.23 ENST00000445907.2
cholinergic receptor, muscarinic 2
chr7_+_154002527 6.93 ENST00000427557.1
dipeptidyl-peptidase 6
chr2_-_170219037 6.70 ENST00000443831.1
low density lipoprotein receptor-related protein 2
chr7_-_128001658 6.50 ENST00000489835.2
ENST00000464607.1
ENST00000489517.1
ENST00000446477.2
ENST00000535159.1
ENST00000435512.1
ENST00000495931.1
proline-rich transmembrane protein 4
chr12_+_121088291 6.18 ENST00000351200.2
calcium binding protein 1
chr10_-_30348439 6.09 ENST00000375377.1
KIAA1462
chr1_+_86046433 6.07 ENST00000451137.2
cysteine-rich, angiogenic inducer, 61
chr7_+_121513374 6.05 ENST00000449182.1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr7_+_154002189 5.96 ENST00000332007.3
dipeptidyl-peptidase 6
chr19_+_30863271 5.95 ENST00000355537.3
zinc finger protein 536
chr7_+_73442487 5.89 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
elastin
chr15_+_40643227 5.66 ENST00000448599.2
proline/histidine/glycine-rich 1
chr15_+_74466012 5.49 ENST00000249842.3
immunoglobulin superfamily containing leucine-rich repeat
chr19_-_35626104 5.49 ENST00000310123.3
ENST00000392225.3
leucine-rich repeat LGI family, member 4
chr11_-_70507867 5.46 ENST00000412252.1
ENST00000409161.1
ENST00000409530.1
SH3 and multiple ankyrin repeat domains 2
chr20_+_34680698 5.46 ENST00000447825.1
erythrocyte membrane protein band 4.1-like 1
chr14_+_42077552 5.35 ENST00000554120.1
leucine rich repeat and fibronectin type III domain containing 5
chr3_-_142608001 5.34 ENST00000295992.3
procollagen C-endopeptidase enhancer 2
chr3_-_58572760 5.33 ENST00000447756.2
family with sequence similarity 107, member A
chr19_+_7660716 5.32 ENST00000160298.4
ENST00000446248.2
calmodulin regulated spectrin-associated protein family, member 3
chr11_+_19798964 5.32 ENST00000527559.2
neuron navigator 2
chr4_-_186732048 5.27 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
sorbin and SH3 domain containing 2
chr20_+_34680620 5.23 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
erythrocyte membrane protein band 4.1-like 1
chr5_+_122424816 5.23 ENST00000407847.4
PR domain containing 6
chr3_-_142607740 5.17 ENST00000485766.1
procollagen C-endopeptidase enhancer 2
chr7_-_140340098 5.16 ENST00000477488.1
DENN/MADD domain containing 2A
chr12_-_86230315 5.13 ENST00000361228.3
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr3_-_187009646 5.13 ENST00000296280.6
ENST00000392470.2
ENST00000169293.6
ENST00000439271.1
ENST00000392472.2
ENST00000392475.2
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr17_+_8213590 5.08 ENST00000361926.3
Rho guanine nucleotide exchange factor (GEF) 15
chr5_+_6448736 5.01 ENST00000399816.3
ubiquitin-conjugating enzyme E2Q family-like 1
chrX_-_20134990 4.88 ENST00000379651.3
ENST00000443379.3
ENST00000379643.5
MAP7 domain containing 2
chr15_+_48009541 4.85 ENST00000536845.2
ENST00000558816.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr9_+_87283430 4.55 ENST00000376214.1
ENST00000376213.1
neurotrophic tyrosine kinase, receptor, type 2
chr7_+_136553824 4.47 ENST00000320658.5
ENST00000453373.1
ENST00000397608.3
ENST00000402486.3
ENST00000401861.1
cholinergic receptor, muscarinic 2
chr20_+_34680595 4.45 ENST00000406771.2
erythrocyte membrane protein band 4.1-like 1
chr4_-_5894777 4.45 ENST00000324989.7
collapsin response mediator protein 1
chr19_-_35625765 4.45 ENST00000591633.1
leucine-rich repeat LGI family, member 4
chr22_+_42372970 4.30 ENST00000291236.11
septin 3
chr22_+_41956767 4.28 ENST00000306149.7
cold shock domain containing C2, RNA binding
chr16_-_70719925 4.26 ENST00000338779.6
metastasis suppressor 1-like
chr1_-_21978312 4.25 ENST00000359708.4
ENST00000290101.4
RAP1 GTPase activating protein
chr8_+_69242957 4.22 ENST00000518698.1
ENST00000539993.1
chromosome 8 open reading frame 34
chr18_+_32290218 4.16 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
dystrobrevin, alpha
chr7_+_73442422 4.13 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
elastin
chr3_-_168865522 4.12 ENST00000464456.1
MDS1 and EVI1 complex locus
chr20_+_10199468 4.10 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr7_+_95401851 4.09 ENST00000447467.2
dynein, cytoplasmic 1, intermediate chain 1
chr20_+_17207636 4.09 ENST00000262545.2
proprotein convertase subtilisin/kexin type 2
chr2_-_67442409 4.06 ENST00000414404.1
ENST00000433133.1
AC078941.1
chr2_-_56150910 3.99 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
EGF containing fibulin-like extracellular matrix protein 1
chr12_+_50451462 3.98 ENST00000447966.2
acid-sensing (proton-gated) ion channel 1
chr1_-_44497024 3.94 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr11_-_70507901 3.92 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SH3 and multiple ankyrin repeat domains 2
chr1_-_234667504 3.89 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
chr22_+_42372764 3.89 ENST00000396426.3
ENST00000406029.1
septin 3
chr11_+_111807863 3.86 ENST00000440460.2
DIX domain containing 1
chr20_+_43343476 3.85 ENST00000372868.2
WNT1 inducible signaling pathway protein 2
chr1_+_218519577 3.84 ENST00000366930.4
ENST00000366929.4
transforming growth factor, beta 2
chr17_+_21279509 3.81 ENST00000583088.1
potassium inwardly-rectifying channel, subfamily J, member 12
chr8_-_33455268 3.80 ENST00000522982.1
dual specificity phosphatase 26 (putative)
chr7_+_73442457 3.76 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
elastin
chr8_-_61193947 3.73 ENST00000317995.4
carbonic anhydrase VIII
chr2_+_56411131 3.69 ENST00000407595.2
coiled-coil domain containing 85A
chr12_-_16761007 3.69 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr4_-_154710210 3.67 ENST00000274063.4
secreted frizzled-related protein 2
chr5_+_169931009 3.67 ENST00000328939.4
ENST00000390656.4
Kv channel interacting protein 1
chr5_-_142000883 3.66 ENST00000359370.6
fibroblast growth factor 1 (acidic)
chrX_+_102585124 3.65 ENST00000332431.4
ENST00000372666.1
transcription elongation factor A (SII)-like 7
chr20_+_17207665 3.63 ENST00000536609.1
proprotein convertase subtilisin/kexin type 2
chr14_+_79745682 3.63 ENST00000557594.1
neurexin 3
chr1_+_22970119 3.55 ENST00000374640.4
ENST00000374639.3
ENST00000374637.1
complement component 1, q subcomponent, C chain
chr8_+_68864330 3.55 ENST00000288368.4
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr11_+_19799327 3.53 ENST00000540292.1
neuron navigator 2
chr9_+_69650263 3.53 ENST00000322495.3
Protein LOC100996643
chr20_+_9049682 3.51 ENST00000334005.3
ENST00000378473.3
phospholipase C, beta 4
chr7_-_14942467 3.49 ENST00000407950.1
ENST00000444700.2
diacylglycerol kinase, beta 90kDa
chr7_+_121513143 3.48 ENST00000393386.2
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr22_+_42372931 3.46 ENST00000328414.8
ENST00000396425.3
septin 3
chr4_-_168155417 3.43 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr11_+_43964055 3.42 ENST00000528572.1
chromosome 11 open reading frame 96
chr9_-_14910990 3.41 ENST00000380881.4
ENST00000422223.2
FRAS1 related extracellular matrix 1
chr12_+_15125954 3.40 ENST00000266395.2
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr19_+_35630344 3.39 ENST00000455515.2
FXYD domain containing ion transport regulator 1
chr3_-_195310802 3.39 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr2_-_56150184 3.38 ENST00000394554.1
EGF containing fibulin-like extracellular matrix protein 1
chr4_-_168155577 3.35 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr19_-_47975417 3.35 ENST00000236877.6
solute carrier family 8 (sodium/calcium exchanger), member 2
chr4_-_186732892 3.34 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
sorbin and SH3 domain containing 2
chr2_+_14772810 3.33 ENST00000295092.2
ENST00000331243.4
family with sequence similarity 84, member A
chr11_+_1430629 3.32 ENST00000528596.1
BR serine/threonine kinase 2
chrX_-_99665262 3.31 ENST00000373034.4
ENST00000255531.7
protocadherin 19
chr3_-_134093275 3.30 ENST00000513145.1
ENST00000422605.2
angiomotin like 2
chr11_-_89224488 3.29 ENST00000534731.1
ENST00000527626.1
NADPH oxidase 4
chr16_+_22825475 3.26 ENST00000261374.3
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr20_-_2781222 3.24 ENST00000380605.2
carboxypeptidase X (M14 family), member 1
chr5_-_142065223 3.24 ENST00000378046.1
fibroblast growth factor 1 (acidic)
chr12_+_50451331 3.22 ENST00000228468.4
acid-sensing (proton-gated) ion channel 1
chr3_-_184870751 3.21 ENST00000335012.2
chromosome 3 open reading frame 70
chr7_+_95401877 3.20 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
dynein, cytoplasmic 1, intermediate chain 1
chr3_-_133748758 3.19 ENST00000493729.1
solute carrier organic anion transporter family, member 2A1
chr7_+_114055052 3.15 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
forkhead box P2
chr22_-_36236623 3.14 ENST00000405409.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr16_-_66959429 3.14 ENST00000420652.1
ENST00000299759.6
Ras-related associated with diabetes
chr17_+_64961026 3.12 ENST00000262138.3
calcium channel, voltage-dependent, gamma subunit 4
chr22_-_36236265 3.11 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RNA binding protein, fox-1 homolog (C. elegans) 2
chr9_+_34652164 3.10 ENST00000441545.2
ENST00000553620.1
interleukin 11 receptor, alpha
chr9_+_103790991 3.08 ENST00000374874.3
Lipid phosphate phosphatase-related protein type 1
chrX_-_74742846 3.07 ENST00000373361.3
zinc finger, DHHC-type containing 15
chr17_+_73750699 3.06 ENST00000584939.1
integrin, beta 4
chr16_+_82068830 3.04 ENST00000199936.4
hydroxysteroid (17-beta) dehydrogenase 2
chr11_-_61348292 3.04 ENST00000539008.1
ENST00000540677.1
ENST00000542836.1
ENST00000542670.1
ENST00000535826.1
ENST00000545053.1
synaptotagmin VII
chr2_+_102686820 3.03 ENST00000409929.1
ENST00000424272.1
interleukin 1 receptor, type I
chr4_-_168155700 3.02 ENST00000357545.4
ENST00000512648.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr1_+_157963063 3.01 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
kin of IRRE like (Drosophila)
chr16_+_6069072 3.01 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_-_170219079 2.99 ENST00000263816.3
low density lipoprotein receptor-related protein 2
chr3_-_73483055 2.98 ENST00000479530.1
PDZ domain containing ring finger 3
chr10_+_123923205 2.98 ENST00000369004.3
ENST00000260733.3
transforming, acidic coiled-coil containing protein 2
chr19_+_35630022 2.97 ENST00000589209.1
FXYD domain containing ion transport regulator 1
chr10_+_88414338 2.97 ENST00000241891.5
ENST00000443292.1
opsin 4
chr17_-_53809473 2.97 ENST00000575734.1
transmembrane protein 100
chr4_-_175041663 2.95 ENST00000503140.1
RP11-148L24.1
chr1_-_177133818 2.95 ENST00000424564.2
ENST00000361833.2
astrotactin 1
chr4_+_62067860 2.93 ENST00000514591.1
latrophilin 3
chr17_+_71161140 2.91 ENST00000357585.2
somatostatin receptor 2
chr19_-_47975106 2.91 ENST00000539381.1
ENST00000594353.1
ENST00000542837.1
solute carrier family 8 (sodium/calcium exchanger), member 2
chr8_-_89339705 2.91 ENST00000286614.6
matrix metallopeptidase 16 (membrane-inserted)
chr8_-_110620284 2.88 ENST00000529690.1
syntabulin (syntaxin-interacting)
chr11_-_89224299 2.88 ENST00000343727.5
ENST00000531342.1
ENST00000375979.3
NADPH oxidase 4
chr4_+_158141806 2.88 ENST00000393815.2
glutamate receptor, ionotropic, AMPA 2
chr16_-_31147020 2.87 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
protease, serine, 8
chr2_+_36923901 2.86 ENST00000457137.2
vitrin
chr9_+_87284675 2.85 ENST00000376208.1
ENST00000304053.6
ENST00000277120.3
neurotrophic tyrosine kinase, receptor, type 2
chr14_+_42076765 2.85 ENST00000298119.4
leucine rich repeat and fibronectin type III domain containing 5
chr6_+_74405501 2.84 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr1_-_44497118 2.83 ENST00000537678.1
ENST00000466926.1
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr17_+_8213539 2.82 ENST00000583529.1
Rho guanine nucleotide exchange factor (GEF) 15
chr7_-_107642348 2.80 ENST00000393561.1
laminin, beta 1
chr1_+_110453514 2.79 ENST00000369802.3
ENST00000420111.2
colony stimulating factor 1 (macrophage)
chr19_-_52227221 2.77 ENST00000222115.1
ENST00000540069.2
hyaluronan synthase 1
chr3_-_9291063 2.77 ENST00000383836.3
SLIT-ROBO Rho GTPase activating protein 3
chr4_-_168155730 2.76 ENST00000502330.1
ENST00000357154.3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr1_-_37499726 2.75 ENST00000373091.3
ENST00000373093.4
glutamate receptor, ionotropic, kainate 3
chr3_-_52479043 2.74 ENST00000231721.2
ENST00000475739.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr1_+_110453109 2.73 ENST00000525659.1
colony stimulating factor 1 (macrophage)
chr20_+_43343886 2.73 ENST00000190983.4
WNT1 inducible signaling pathway protein 2
chr6_-_53530474 2.73 ENST00000370905.3
kelch-like family member 31
chr10_+_123923105 2.72 ENST00000368999.1
transforming, acidic coiled-coil containing protein 2
chr11_-_18813353 2.71 ENST00000358540.2
ENST00000396171.4
ENST00000396167.2
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr12_-_16761117 2.71 ENST00000538051.1
LIM domain only 3 (rhombotin-like 2)
chr12_-_71533055 2.69 ENST00000552128.1
tetraspanin 8
chr7_+_73442102 2.69 ENST00000445912.1
ENST00000252034.7
elastin
chr8_-_134309335 2.68 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
N-myc downstream regulated 1
chr8_-_143696833 2.68 ENST00000356613.2
activity-regulated cytoskeleton-associated protein
chr16_+_82660560 2.68 ENST00000268613.10
ENST00000565636.1
ENST00000431540.3
ENST00000428848.3
cadherin 13
chr2_-_218843623 2.68 ENST00000413280.1
tensin 1
chr19_+_57019212 2.67 ENST00000308031.5
ENST00000591537.1
zinc finger protein 471
chr14_+_105047478 2.63 ENST00000410013.1
chromosome 14 open reading frame 180
chr1_-_171621815 2.62 ENST00000037502.6
myocilin, trabecular meshwork inducible glucocorticoid response
chr2_-_27341765 2.62 ENST00000405600.1
cell growth regulator with EF-hand domain 1
chr12_-_85306562 2.61 ENST00000551612.1
ENST00000450363.3
ENST00000552192.1
solute carrier family 6 (neutral amino acid transporter), member 15
chrX_-_71933888 2.60 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
phosphorylase kinase, alpha 1 (muscle)
chr22_+_32439019 2.59 ENST00000266088.4
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr5_-_149669192 2.58 ENST00000398376.3
calcium/calmodulin-dependent protein kinase II alpha
chr17_-_74533963 2.58 ENST00000293230.5
cytoglobin
chr8_+_61969714 2.56 ENST00000522621.1
clavesin 1
chr2_-_238499337 2.55 ENST00000411462.1
ENST00000409822.1
RAB17, member RAS oncogene family
chr1_+_210406121 2.54 ENST00000367012.3
SERTA domain containing 4
chr20_+_43343517 2.54 ENST00000372865.4
WNT1 inducible signaling pathway protein 2
chr19_+_30719410 2.52 ENST00000585628.1
ENST00000591488.1
zinc finger protein 536
chr3_-_58613323 2.52 ENST00000474531.1
ENST00000465970.1
family with sequence similarity 107, member A
chr14_-_54420133 2.52 ENST00000559501.1
ENST00000558984.1
bone morphogenetic protein 4
chr1_-_85930246 2.51 ENST00000426972.3
dimethylarginine dimethylaminohydrolase 1
chr20_+_10199566 2.51 ENST00000430336.1
synaptosomal-associated protein, 25kDa
chr5_-_146889619 2.50 ENST00000343218.5
dihydropyrimidinase-like 3
chrX_-_119445263 2.49 ENST00000309720.5
transmembrane protein 255A
chr3_+_174577070 2.48 ENST00000454872.1
N-acetylated alpha-linked acidic dipeptidase-like 2
chr13_-_37494365 2.47 ENST00000350148.5
SMAD family member 9
chr2_-_27341966 2.47 ENST00000402394.1
ENST00000402550.1
ENST00000260595.5
cell growth regulator with EF-hand domain 1
chr5_+_52285144 2.46 ENST00000296585.5
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr11_-_79151695 2.45 ENST00000278550.7
teneurin transmembrane protein 4
chrX_+_113818545 2.43 ENST00000371951.1
ENST00000276198.1
ENST00000371950.3
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
chr1_-_75139397 2.43 ENST00000326665.5
chromosome 1 open reading frame 173
chr11_-_107582775 2.42 ENST00000305991.2
sarcolipin
chr11_-_89224638 2.41 ENST00000535633.1
ENST00000263317.4
NADPH oxidase 4
chr4_-_46996424 2.40 ENST00000264318.3
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr15_+_33603147 2.40 ENST00000415757.3
ENST00000389232.4
ryanodine receptor 3
chr1_+_110453462 2.39 ENST00000488198.1
colony stimulating factor 1 (macrophage)
chr4_-_142054590 2.39 ENST00000306799.3
ring finger protein 150
chr11_-_89224508 2.38 ENST00000525196.1
NADPH oxidase 4
chr13_-_37494391 2.37 ENST00000379826.4
SMAD family member 9
chr5_-_142077569 2.36 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
fibroblast growth factor 1 (acidic)
chr1_+_209757051 2.35 ENST00000009105.1
ENST00000423146.1
ENST00000361322.2
calcium/calmodulin-dependent protein kinase IG
chrX_-_119445306 2.35 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
transmembrane protein 255A
chr17_+_37782955 2.34 ENST00000580825.1
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr4_+_41361616 2.33 ENST00000513024.1
LIM and calponin homology domains 1
chr15_+_96875657 2.33 ENST00000559679.1
ENST00000394171.2
nuclear receptor subfamily 2, group F, member 2
chr11_+_131240373 2.33 ENST00000374791.3
ENST00000436745.1
neurotrimin

Network of associatons between targets according to the STRING database.

First level regulatory network of EPAS1_BCL3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.6 GO:1990926 short-term synaptic potentiation(GO:1990926)
2.9 8.6 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
2.2 11.2 GO:1904141 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
2.1 17.1 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
1.9 5.7 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
1.7 5.1 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
1.7 13.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
1.6 7.9 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.6 4.7 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
1.5 7.7 GO:0030070 insulin processing(GO:0030070)
1.5 4.5 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
1.3 3.8 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
1.2 4.9 GO:0042662 negative regulation of mesodermal cell fate specification(GO:0042662)
1.2 7.4 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
1.2 6.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
1.2 2.4 GO:0072197 ureter morphogenesis(GO:0072197)
1.2 5.8 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
1.2 10.4 GO:0021564 vagus nerve development(GO:0021564)
1.0 7.2 GO:0050915 sensory perception of sour taste(GO:0050915)
1.0 4.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
1.0 1.0 GO:0032095 regulation of response to food(GO:0032095)
1.0 2.9 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.9 3.8 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.9 14.0 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.9 2.6 GO:0008057 eye pigment granule organization(GO:0008057)
0.9 3.5 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.8 2.5 GO:0033341 regulation of collagen binding(GO:0033341)
0.8 7.4 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.8 2.4 GO:0032289 central nervous system myelin formation(GO:0032289)
0.8 9.5 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.8 4.0 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.8 3.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.8 3.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.8 7.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.7 2.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.7 0.7 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.7 4.8 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.7 2.7 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.7 4.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.7 5.3 GO:0072675 osteoclast fusion(GO:0072675)
0.7 2.6 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.6 1.9 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.6 1.9 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.6 7.3 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.6 2.4 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.6 1.8 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.6 2.9 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.6 2.3 GO:0009956 radial pattern formation(GO:0009956)
0.6 2.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.6 2.8 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.6 5.5 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.6 8.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.6 13.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 3.8 GO:0034436 glycoprotein transport(GO:0034436)
0.5 2.7 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.5 4.8 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.5 5.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.5 2.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.5 3.0 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.5 11.6 GO:0035641 locomotory exploration behavior(GO:0035641)
0.5 15.1 GO:0071625 vocalization behavior(GO:0071625)
0.5 1.4 GO:0006710 androgen catabolic process(GO:0006710)
0.5 1.4 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.5 3.7 GO:0060677 ureteric bud elongation(GO:0060677)
0.5 6.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.5 0.9 GO:0001575 globoside metabolic process(GO:0001575)
0.4 8.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.4 1.3 GO:0032880 regulation of protein localization(GO:0032880)
0.4 1.7 GO:0048686 modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.4 3.0 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.4 1.7 GO:0010669 epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.4 0.4 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.4 2.0 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.4 5.1 GO:0042940 D-amino acid transport(GO:0042940)
0.4 3.5 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.4 2.8 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.4 1.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.4 1.6 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.4 7.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.4 1.6 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.4 3.9 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.4 4.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.4 1.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.4 4.2 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.4 4.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.4 1.9 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.4 3.7 GO:0015820 leucine transport(GO:0015820)
0.4 1.5 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.4 2.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.4 1.1 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.3 5.8 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.3 12.6 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.3 6.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 4.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.3 1.6 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.3 2.3 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 12.9 GO:0050667 homocysteine metabolic process(GO:0050667)
0.3 1.9 GO:0097327 response to antineoplastic agent(GO:0097327)
0.3 1.6 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.3 5.0 GO:0035878 nail development(GO:0035878)
0.3 3.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.3 1.5 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) positive regulation of phospholipid catabolic process(GO:0060697)
0.3 9.9 GO:0042359 vitamin D metabolic process(GO:0042359)
0.3 7.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.3 0.6 GO:0099624 atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.3 1.5 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.3 3.5 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.3 1.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.3 1.5 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.3 1.7 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 2.6 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.3 3.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.3 2.0 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.3 0.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 5.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.3 1.1 GO:1903060 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.3 3.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.3 3.5 GO:0002158 osteoclast proliferation(GO:0002158)
0.3 1.3 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.3 2.1 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.3 0.5 GO:0006473 protein acetylation(GO:0006473)
0.3 1.0 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.3 6.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.3 1.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.3 0.8 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2 1.7 GO:0014826 cellular magnesium ion homeostasis(GO:0010961) vein smooth muscle contraction(GO:0014826)
0.2 0.7 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.2 0.7 GO:0006173 dADP biosynthetic process(GO:0006173) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.2 1.0 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.2 1.2 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.2 1.9 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.2 1.0 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.2 2.8 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.2 2.8 GO:0006600 creatine metabolic process(GO:0006600)
0.2 0.9 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.2 3.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 10.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 3.0 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.2 3.6 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.2 13.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 0.2 GO:0097195 pilomotor reflex(GO:0097195)
0.2 0.9 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.2 1.1 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.2 1.1 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057) negative regulation of muscle hyperplasia(GO:0014740)
0.2 1.7 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.2 2.6 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2 2.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 12.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 4.4 GO:0046415 urate metabolic process(GO:0046415)
0.2 2.9 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.2 4.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 0.8 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 1.4 GO:0071461 cellular response to redox state(GO:0071461)
0.2 1.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 1.6 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.2 0.6 GO:0060319 coronary vein morphogenesis(GO:0003169) primitive erythrocyte differentiation(GO:0060319) cardiac vascular smooth muscle cell development(GO:0060948) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 1.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 1.0 GO:0097475 motor neuron migration(GO:0097475)
0.2 2.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 0.9 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.2 3.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 2.8 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.2 2.2 GO:1902866 negative regulation of excitatory postsynaptic potential(GO:0090394) regulation of retina development in camera-type eye(GO:1902866)
0.2 1.7 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.2 2.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 2.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 0.7 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 0.5 GO:2001054 regulation of mesenchymal cell apoptotic process(GO:2001053) negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.2 0.5 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 0.7 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 3.8 GO:0007602 phototransduction(GO:0007602)
0.2 20.5 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.2 1.0 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.2 1.7 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 1.2 GO:2001023 regulation of response to drug(GO:2001023)
0.2 0.7 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.2 1.3 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.2 2.5 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.2 1.0 GO:0033603 positive regulation of dopamine secretion(GO:0033603) negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.2 1.8 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.2 2.9 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 0.8 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.2 2.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 3.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 14.7 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 0.7 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 1.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.4 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.7 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.4 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 2.6 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 1.0 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 0.9 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 2.0 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.1 2.0 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.1 3.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 1.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.7 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 1.2 GO:0050821 protein stabilization(GO:0050821)
0.1 5.4 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.4 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 1.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.8 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 1.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 1.5 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 2.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.7 GO:0022602 ovulation cycle process(GO:0022602)
0.1 1.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 1.8 GO:0015705 iodide transport(GO:0015705)
0.1 0.5 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 1.8 GO:0099638 endosome to plasma membrane protein transport(GO:0099638)
0.1 1.5 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 5.4 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 1.2 GO:0048266 behavioral response to pain(GO:0048266)
0.1 1.3 GO:0032962 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.1 6.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.9 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 4.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 1.9 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.9 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.1 1.1 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 4.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.6 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 1.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 7.0 GO:0008542 visual learning(GO:0008542)
0.1 0.3 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 0.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.7 GO:0021756 striatum development(GO:0021756)
0.1 3.5 GO:0032098 regulation of appetite(GO:0032098)
0.1 0.2 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.5 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 1.0 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 2.6 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 1.6 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.9 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.6 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
0.1 1.5 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.5 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 3.6 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 1.4 GO:0001778 plasma membrane repair(GO:0001778)
0.1 5.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 7.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 1.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 4.4 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 3.8 GO:0010107 potassium ion import(GO:0010107)
0.1 1.5 GO:0072189 ureter development(GO:0072189)
0.1 0.6 GO:0015692 lead ion transport(GO:0015692)
0.1 0.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.9 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 1.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.2 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
0.1 4.4 GO:0008038 neuron recognition(GO:0008038)
0.1 0.9 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.1 3.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.6 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 1.5 GO:0015732 prostaglandin transport(GO:0015732)
0.1 0.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 1.2 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.1 4.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.5 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.1 0.3 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 2.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.6 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 0.2 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 2.3 GO:0045332 phospholipid translocation(GO:0045332)
0.1 2.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 1.9 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.1 0.5 GO:0033563 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834) dorsal/ventral axon guidance(GO:0033563)
0.1 0.5 GO:0008544 epidermis development(GO:0008544)
0.1 2.2 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.1 1.2 GO:0035640 exploration behavior(GO:0035640)
0.1 2.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.3 GO:0021681 cerebellar granular layer development(GO:0021681)
0.1 1.7 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.1 0.5 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 1.3 GO:0009790 embryo development(GO:0009790)
0.1 0.2 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.8 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1 0.9 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 1.0 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 1.5 GO:0006069 ethanol oxidation(GO:0006069)
0.1 1.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 2.0 GO:0030517 negative regulation of axon extension(GO:0030517)
0.1 3.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 2.5 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.1 0.1 GO:2001303 regulation of engulfment of apoptotic cell(GO:1901074) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.1 0.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.3 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.1 1.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.9 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 1.8 GO:0001502 cartilage condensation(GO:0001502)
0.1 1.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.7 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.9 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 2.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 2.4 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.9 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.1 1.2 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.1 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 7.9 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 0.8 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 1.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.6 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1 4.2 GO:0035329 hippo signaling(GO:0035329)
0.1 0.8 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 3.1 GO:0010761 fibroblast migration(GO:0010761)
0.1 6.8 GO:0021987 cerebral cortex development(GO:0021987)
0.1 1.0 GO:0000338 protein deneddylation(GO:0000338)
0.1 1.0 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.1 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.3 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 1.8 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 0.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 2.1 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 0.4 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 1.5 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 0.4 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 2.0 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 1.0 GO:0021510 spinal cord development(GO:0021510)
0.1 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 2.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.4 GO:2000181 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.1 0.1 GO:1900673 olefin metabolic process(GO:1900673)
0.1 2.9 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 4.3 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 6.0 GO:0001764 neuron migration(GO:0001764)
0.1 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 1.7 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.4 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 0.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.2 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.5 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.8 GO:0014870 response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 1.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 5.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 2.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.6 GO:0015886 heme transport(GO:0015886)
0.0 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 2.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.9 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.3 GO:0008595 blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 3.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.9 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.6 GO:0014029 neural crest formation(GO:0014029)
0.0 1.1 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 1.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.8 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.5 GO:0045932 negative regulation of muscle contraction(GO:0045932)
0.0 1.3 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 1.3 GO:0009799 specification of symmetry(GO:0009799)
0.0 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.3 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.9 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 1.0 GO:0097435 fibril organization(GO:0097435)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:0071028 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.6 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.9 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 5.1 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 1.9 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.9 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0035826 rubidium ion transport(GO:0035826) regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547) regulation of rubidium ion transport(GO:2000680)
0.0 0.3 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.0 3.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.5 GO:0003338 metanephros morphogenesis(GO:0003338)
0.0 1.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.2 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0050976 sensory perception of touch(GO:0050975) detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.5 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.5 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 1.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.4 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.8 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.2 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.9 GO:0007586 digestion(GO:0007586)
0.0 1.1 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 0.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.6 GO:0007141 male meiosis I(GO:0007141)
0.0 0.0 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 1.3 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.3 GO:0000012 single strand break repair(GO:0000012)
0.0 0.4 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.1 GO:0036363 transforming growth factor beta activation(GO:0036363) mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.7 GO:0042461 photoreceptor cell development(GO:0042461)
0.0 0.7 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 2.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.0 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 1.3 GO:0097581 lamellipodium organization(GO:0097581)
0.0 1.7 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:0032472 Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.0 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 1.7 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 2.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.6 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 5.2 GO:0001558 regulation of cell growth(GO:0001558)
0.0 1.1 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 1.6 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:0010744 positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.0 0.6 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.5 GO:0051259 protein oligomerization(GO:0051259)
0.0 0.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.0 GO:0055001 muscle cell development(GO:0055001)
0.0 1.2 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 2.0 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 1.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.5 GO:0072534 perineuronal net(GO:0072534)
2.3 11.7 GO:0032279 asymmetric synapse(GO:0032279)
1.6 17.6 GO:0071953 elastic fiber(GO:0071953)
1.6 11.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.9 2.8 GO:0043257 laminin-8 complex(GO:0043257)
0.9 6.2 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.8 6.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.8 4.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.7 2.0 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.6 17.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.6 9.4 GO:0005883 neurofilament(GO:0005883)
0.5 1.6 GO:0005588 collagen type V trimer(GO:0005588)
0.5 11.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.5 1.5 GO:0098855 HCN channel complex(GO:0098855)
0.5 15.4 GO:0005614 interstitial matrix(GO:0005614)
0.5 2.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.4 2.5 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.4 4.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 1.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.4 5.0 GO:0030314 junctional membrane complex(GO:0030314)
0.4 1.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 1.5 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.4 5.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.4 2.9 GO:1990393 3M complex(GO:1990393)
0.3 3.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 1.0 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.3 0.3 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.3 6.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.3 2.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.3 9.1 GO:0031045 dense core granule(GO:0031045)
0.3 10.9 GO:0033268 node of Ranvier(GO:0033268)
0.3 1.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3 2.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.3 0.8 GO:0036117 hyaluranon cable(GO:0036117)
0.2 0.7 GO:0001534 radial spoke(GO:0001534)
0.2 0.7 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.2 1.8 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.2 2.5 GO:0005610 laminin-5 complex(GO:0005610)
0.2 2.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 5.3 GO:0005915 zonula adherens(GO:0005915)
0.2 4.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 1.5 GO:0045298 tubulin complex(GO:0045298)
0.2 0.4 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 4.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 0.8 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 7.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 1.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 0.7 GO:0005879 axonemal microtubule(GO:0005879)
0.2 23.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 1.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 37.4 GO:0043204 perikaryon(GO:0043204)
0.2 1.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 2.9 GO:0097433 dense body(GO:0097433)
0.2 2.5 GO:0030673 axolemma(GO:0030673)
0.2 1.1 GO:1990812 growth cone filopodium(GO:1990812)
0.2 7.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 8.6 GO:0005581 collagen trimer(GO:0005581)
0.2 5.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 4.3 GO:0030056 hemidesmosome(GO:0030056)
0.2 0.8 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.2 0.8 GO:0005602 complement component C1 complex(GO:0005602)
0.2 0.9 GO:0044308 axonal spine(GO:0044308)
0.1 3.0 GO:0043203 axon hillock(GO:0043203)
0.1 14.4 GO:0031526 brush border membrane(GO:0031526)
0.1 1.0 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 9.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.4 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 5.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.7 GO:0033643 host cell part(GO:0033643)
0.1 4.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 4.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 2.7 GO:0032433 filopodium tip(GO:0032433)
0.1 4.0 GO:0071141 SMAD protein complex(GO:0071141)
0.1 2.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 2.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 2.2 GO:0070382 exocytic vesicle(GO:0070382)
0.1 2.1 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 28.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 5.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 57.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 9.7 GO:0043195 terminal bouton(GO:0043195)
0.1 0.5 GO:0071942 XPC complex(GO:0071942)
0.1 1.0 GO:0035253 ciliary rootlet(GO:0035253)
0.1 2.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 8.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 2.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.9 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 3.0 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 15.8 GO:0030018 Z disc(GO:0030018)
0.1 1.1 GO:0030478 actin cap(GO:0030478)
0.1 2.0 GO:0010369 chromocenter(GO:0010369)
0.1 0.5 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.5 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.3 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.1 6.3 GO:0005796 Golgi lumen(GO:0005796)
0.1 2.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 5.9 GO:0042383 sarcolemma(GO:0042383)
0.1 3.0 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.8 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.9 GO:0044306 neuron projection terminus(GO:0044306)
0.1 14.7 GO:0031012 extracellular matrix(GO:0031012)
0.1 7.9 GO:0055037 recycling endosome(GO:0055037)
0.1 0.6 GO:0032590 dendrite membrane(GO:0032590)
0.1 15.5 GO:0045202 synapse(GO:0045202)
0.1 1.4 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 1.1 GO:0005901 caveola(GO:0005901)
0.1 1.9 GO:0016580 Sin3 complex(GO:0016580)
0.1 19.0 GO:0097060 synaptic membrane(GO:0097060)
0.1 3.6 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.8 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 1.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.6 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.5 GO:0034464 BBSome(GO:0034464)
0.0 6.9 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 10.5 GO:0098793 presynapse(GO:0098793)
0.0 15.2 GO:0030425 dendrite(GO:0030425)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 4.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 2.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0005833 hemoglobin complex(GO:0005833)
0.0 3.2 GO:0005884 actin filament(GO:0005884)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 2.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0034705 potassium channel complex(GO:0034705)
0.0 5.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 3.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 9.4 GO:0043005 neuron projection(GO:0043005)
0.0 0.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 15.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.9 GO:0030496 midbody(GO:0030496)
0.0 1.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.0 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 3.7 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 2.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.6 GO:0015375 glycine:sodium symporter activity(GO:0015375)
1.7 8.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.7 13.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.3 8.9 GO:0042954 lipoprotein transporter activity(GO:0042954)
1.2 3.7 GO:0005298 proline:sodium symporter activity(GO:0005298)
1.2 7.4 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
1.2 4.8 GO:0047888 fatty acid peroxidase activity(GO:0047888)
1.2 7.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
1.1 4.3 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
1.0 9.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
1.0 8.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
1.0 3.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.0 5.8 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.9 3.8 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.9 13.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.8 4.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.8 8.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.8 5.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.7 6.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.7 2.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.7 2.1 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.7 2.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.7 5.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.6 1.9 GO:0070698 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)
0.6 1.9 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.6 3.8 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.6 3.0 GO:0055100 adiponectin binding(GO:0055100)
0.6 2.4 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.6 0.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.6 2.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.6 8.0 GO:0038132 neuregulin binding(GO:0038132)
0.5 3.8 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.5 1.6 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.5 3.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.5 15.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 9.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.5 1.5 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.5 0.5 GO:0016015 morphogen activity(GO:0016015)
0.5 1.9 GO:0035939 microsatellite binding(GO:0035939)
0.5 1.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.5 2.3 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.5 1.4 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.4 3.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.4 15.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.4 3.0 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.4 4.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.4 3.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 1.5 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.4 1.5 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.4 1.5 GO:0099609 microtubule lateral binding(GO:0099609)
0.4 3.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 15.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 3.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.4 3.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.4 2.9 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.4 2.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.4 12.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.4 1.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.3 1.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 6.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 1.0 GO:0005119 smoothened binding(GO:0005119)
0.3 3.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.4 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.3 5.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.3 1.0 GO:0033149 FFAT motif binding(GO:0033149)
0.3 21.6 GO:0030507 spectrin binding(GO:0030507)
0.3 2.9 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.3 11.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.3 5.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.3 1.5 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.3 0.9 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.3 1.5 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.3 1.8 GO:1902444 riboflavin binding(GO:1902444)
0.3 1.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 2.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.3 0.9 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.3 1.7 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 2.8 GO:0004111 creatine kinase activity(GO:0004111)
0.3 6.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 22.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 1.6 GO:0034711 inhibin binding(GO:0034711)
0.3 5.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.3 0.8 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.3 0.8 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.3 2.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.3 4.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 1.8 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.3 1.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 11.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 0.7 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.2 4.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 2.0 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.2 2.2 GO:0042835 BRE binding(GO:0042835)
0.2 1.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 7.5 GO:0031005 filamin binding(GO:0031005)
0.2 5.7 GO:0003924 GTPase activity(GO:0003924)
0.2 1.8 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 0.7 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.2 3.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.2 9.1 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 2.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.2 3.4 GO:0070700 BMP receptor binding(GO:0070700)
0.2 12.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 1.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 1.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 0.6 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 3.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 1.2 GO:0032089 NACHT domain binding(GO:0032089)
0.2 2.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 3.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.2 4.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 1.0 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 10.5 GO:0016504 peptidase activator activity(GO:0016504)
0.2 1.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 3.1 GO:0036122 BMP binding(GO:0036122)
0.2 5.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 1.0 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 0.9 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 0.6 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.2 2.4 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 3.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 0.5 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 5.6 GO:0002162 dystroglycan binding(GO:0002162)
0.2 0.7 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.2 2.6 GO:0032027 myosin light chain binding(GO:0032027)
0.2 1.0 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.2 22.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 1.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 6.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 2.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.2 3.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 1.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 3.5 GO:0043295 glutathione binding(GO:0043295)
0.2 0.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 1.4 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2 0.9 GO:0005499 vitamin D binding(GO:0005499)
0.2 7.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 1.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 3.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.2 4.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 0.6 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 2.0 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.4 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 6.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.4 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.1 3.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 5.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.8 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.4 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 2.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 1.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 3.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 16.9 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.7 GO:0015232 xenobiotic-transporting ATPase activity(GO:0008559) heme transporter activity(GO:0015232)
0.1 4.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 3.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.6 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 3.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 1.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.6 GO:0005522 profilin binding(GO:0005522)
0.1 1.4 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.9 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 7.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 9.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 0.5 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 2.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.6 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 1.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 3.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.2 GO:0008430 selenium binding(GO:0008430)
0.1 4.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.7 GO:0043237 laminin-1 binding(GO:0043237)
0.1 5.6 GO:0050699 WW domain binding(GO:0050699)
0.1 1.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.4 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1 2.3 GO:0043236 laminin binding(GO:0043236)
0.1 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.1 3.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 2.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 2.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 15.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 7.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 3.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 6.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 7.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 6.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 2.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 4.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 6.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 4.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.9 GO:0043621 protein self-association(GO:0043621)
0.1 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 2.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.1 0.6 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.2 GO:0070064 proline-rich region binding(GO:0070064)
0.1 2.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.5 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 2.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 10.9 GO:0008201 heparin binding(GO:0008201)
0.1 3.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.9 GO:0004568 chitinase activity(GO:0004568)
0.1 1.1 GO:0008013 beta-catenin binding(GO:0008013)
0.1 3.8 GO:0019003 GDP binding(GO:0019003)
0.1 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.5 GO:0031014 troponin T binding(GO:0031014)
0.0 17.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 2.2 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 1.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 1.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 3.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 3.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.9 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 1.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0016898 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 3.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 2.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 1.4 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.8 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.1 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 5.2 GO:0005525 GTP binding(GO:0005525)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0008092 cytoskeletal protein binding(GO:0008092)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 15.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 17.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 5.1 PID ALK2 PATHWAY ALK2 signaling events
0.2 1.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 6.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 62.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 7.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 7.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 12.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 13.6 PID LKB1 PATHWAY LKB1 signaling events
0.1 7.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 12.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 11.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 8.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 7.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 7.2 PID FGF PATHWAY FGF signaling pathway
0.1 4.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 7.3 PID BMP PATHWAY BMP receptor signaling
0.1 3.5 PID REELIN PATHWAY Reelin signaling pathway
0.1 1.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 7.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 6.3 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 3.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 24.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 1.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 3.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 3.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 4.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.5 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.7 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 8.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.6 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 11.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.7 11.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.4 22.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.4 8.7 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.4 5.3 REACTOME OPSINS Genes involved in Opsins
0.3 7.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 14.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.3 15.4 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 6.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 9.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 6.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 10.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 0.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2 2.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 6.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 14.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 3.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 0.9 REACTOME PI3K EVENTS IN ERBB2 SIGNALING Genes involved in PI3K events in ERBB2 signaling
0.2 5.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 6.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 4.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 5.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 4.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 10.4 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.1 6.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 3.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 4.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 3.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 3.9 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 2.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 4.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 4.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 3.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 1.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 4.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 3.3 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 3.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 5.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 2.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 9.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 1.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 2.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 7.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 3.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 2.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.0 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.9 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 1.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 6.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.6 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 2.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon