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Illumina Body Map 2, young vs old

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Results for ESRRB_ESRRG

Z-value: 0.54

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Transcription factors associated with ESRRB_ESRRG

Gene Symbol Gene ID Gene Info
ENSG00000119715.10 estrogen related receptor beta
ENSG00000196482.12 estrogen related receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESRRGhg19_v2_chr1_-_216896780_2168968000.811.9e-08Click!
ESRRBhg19_v2_chr14_+_76776957_767770610.593.9e-04Click!

Activity profile of ESRRB_ESRRG motif

Sorted Z-values of ESRRB_ESRRG motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_42743006 16.87 ENST00000310417.5
hedgehog acyltransferase-like
chr20_-_62130474 16.78 ENST00000217182.3
eukaryotic translation elongation factor 1 alpha 2
chr5_+_80529104 15.93 ENST00000254035.4
ENST00000511719.1
ENST00000437669.1
ENST00000424301.2
ENST00000505060.1
creatine kinase, mitochondrial 2 (sarcomeric)
chr3_-_42744130 12.72 ENST00000417472.1
ENST00000442469.1
hedgehog acyltransferase-like
chr11_-_790060 12.60 ENST00000330106.4
cell cycle exit and neuronal differentiation 1
chr19_-_55669093 10.77 ENST00000344887.5
troponin I type 3 (cardiac)
chr16_+_58535372 10.32 ENST00000566656.1
ENST00000566618.1
NDRG family member 4
chr1_+_169077133 10.29 ENST00000494797.1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr22_+_31518938 9.96 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
inositol polyphosphate-5-phosphatase J
chr2_+_220491973 9.49 ENST00000358055.3
solute carrier family 4 (anion exchanger), member 3
chr1_+_169077172 9.46 ENST00000499679.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_+_202995611 9.30 ENST00000367240.2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr14_-_21492251 9.20 ENST00000554398.1
NDRG family member 2
chr10_-_50970382 9.11 ENST00000419399.1
ENST00000432695.1
oxoglutarate dehydrogenase-like
chr1_+_236849754 8.66 ENST00000542672.1
ENST00000366578.4
actinin, alpha 2
chr3_+_121311966 8.55 ENST00000338040.4
F-box protein 40
chr3_-_42744312 8.51 ENST00000416756.1
ENST00000441594.1
hedgehog acyltransferase-like
chr1_+_207226574 8.24 ENST00000367080.3
ENST00000367079.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr1_+_153600869 8.09 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100 calcium binding protein A1
chr3_-_38691119 8.04 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
sodium channel, voltage-gated, type V, alpha subunit
chr15_+_43985725 7.96 ENST00000413453.2
creatine kinase, mitochondrial 1A
chr15_+_43885252 7.72 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
creatine kinase, mitochondrial 1B
chr15_+_43886057 7.59 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
creatine kinase, mitochondrial 1B
chr9_+_95997205 7.58 ENST00000411624.1
WNK lysine deficient protein kinase 2
chr10_-_50970322 7.56 ENST00000374103.4
oxoglutarate dehydrogenase-like
chr3_-_42744270 7.50 ENST00000457462.1
hedgehog acyltransferase-like
chr5_+_149569520 7.49 ENST00000230671.2
ENST00000524041.1
solute carrier family 6 (neurotransmitter transporter), member 7
chr15_+_43985084 7.44 ENST00000434505.1
ENST00000411750.1
creatine kinase, mitochondrial 1A
chr14_-_21491477 7.38 ENST00000298684.5
ENST00000557169.1
ENST00000553563.1
NDRG family member 2
chr14_-_21492113 7.15 ENST00000554094.1
NDRG family member 2
chr2_+_220492116 7.12 ENST00000373760.2
solute carrier family 4 (anion exchanger), member 3
chr6_-_97345689 6.96 ENST00000316149.7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
chr12_-_111358372 6.59 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chr19_-_45826125 6.35 ENST00000221476.3
creatine kinase, muscle
chr19_+_589893 6.33 ENST00000251287.2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr4_-_186661365 6.13 ENST00000452351.1
sorbin and SH3 domain containing 2
chr10_-_101190202 6.01 ENST00000543866.1
ENST00000370508.5
glutamic-oxaloacetic transaminase 1, soluble
chr16_-_66952779 5.86 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
cadherin 16, KSP-cadherin
chr4_-_21699380 5.83 ENST00000382148.3
Kv channel interacting protein 4
chr1_-_144995074 5.71 ENST00000534536.1
phosphodiesterase 4D interacting protein
chr2_+_220492287 5.47 ENST00000273063.6
ENST00000373762.3
solute carrier family 4 (anion exchanger), member 3
chr18_-_12377001 5.47 ENST00000590811.1
AFG3-like AAA ATPase 2
chr2_+_220492373 5.37 ENST00000317151.3
solute carrier family 4 (anion exchanger), member 3
chr5_-_160975130 5.32 ENST00000274547.2
ENST00000520240.1
ENST00000517901.1
ENST00000353437.6
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr18_-_56296182 5.27 ENST00000361673.3
alpha-kinase 2
chr18_-_44336998 5.22 ENST00000315087.7
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr11_+_86667117 5.21 ENST00000531827.1
RP11-736K20.6
chr20_+_58179582 5.10 ENST00000371015.1
ENST00000395639.4
phosphatase and actin regulator 3
chr7_+_123241908 5.09 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ankyrin repeat and SOCS box containing 15
chr17_-_27503770 5.05 ENST00000533112.1
myosin XVIIIA
chr1_-_144995002 4.99 ENST00000369356.4
phosphodiesterase 4D interacting protein
chr16_-_66952742 4.99 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
cadherin 16, KSP-cadherin
chr14_-_103987679 4.96 ENST00000553610.1
creatine kinase, brain
chr19_-_4517613 4.88 ENST00000301286.3
perilipin 4
chr1_+_169075554 4.84 ENST00000367815.4
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr19_-_51192661 4.78 ENST00000391813.1
SH3 and multiple ankyrin repeat domains 1
chr1_-_217250231 4.77 ENST00000493748.1
ENST00000463665.1
estrogen-related receptor gamma
chr22_-_24110063 4.75 ENST00000520222.1
ENST00000401675.3
coiled-coil-helix-coiled-coil-helix domain containing 10
chr17_-_42988004 4.75 ENST00000586125.1
ENST00000591880.1
glial fibrillary acidic protein
chr15_-_83621435 4.73 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
homer homolog 2 (Drosophila)
chr18_-_43678241 4.71 ENST00000593152.2
ENST00000589252.1
ENST00000590665.1
ENST00000398752.6
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr11_-_111794446 4.70 ENST00000527950.1
crystallin, alpha B
chr1_-_201342364 4.54 ENST00000236918.7
ENST00000367317.4
ENST00000367315.2
ENST00000360372.4
troponin T type 2 (cardiac)
chr12_+_119616447 4.43 ENST00000281938.2
heat shock 22kDa protein 8
chr1_-_145075847 4.41 ENST00000530740.1
ENST00000369359.4
phosphodiesterase 4D interacting protein
chr12_-_57039739 4.39 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr1_-_917466 4.36 ENST00000341290.2
chromosome 1 open reading frame 170
chr13_+_22245522 4.34 ENST00000382353.5
fibroblast growth factor 9
chr11_+_66059339 4.26 ENST00000327259.4
transmembrane protein 151A
chr16_+_21964662 4.26 ENST00000561553.1
ENST00000565331.1
ubiquinol-cytochrome c reductase core protein II
chr3_-_42845922 4.25 ENST00000452906.2
HIG1 hypoxia inducible domain family, member 1A
chr16_+_6069586 4.24 ENST00000547372.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_-_241683001 4.19 ENST00000366560.3
fumarate hydratase
chr18_-_12377283 4.16 ENST00000269143.3
AFG3-like AAA ATPase 2
chr2_-_176046391 4.15 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr3_+_186435065 4.13 ENST00000287611.2
ENST00000265023.4
kininogen 1
chr8_+_145149930 4.10 ENST00000318911.4
cytochrome c-1
chr20_+_58152524 4.09 ENST00000359926.3
phosphatase and actin regulator 3
chr9_-_130637244 4.09 ENST00000373156.1
adenylate kinase 1
chr7_-_113559104 4.09 ENST00000284601.3
protein phosphatase 1, regulatory subunit 3A
chr22_-_29711645 4.08 ENST00000401450.3
RAS-like, family 10, member A
chr18_-_44336754 4.08 ENST00000538168.1
ENST00000536490.1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr1_-_145076186 4.07 ENST00000369348.3
phosphodiesterase 4D interacting protein
chr7_+_56032270 4.07 ENST00000322090.3
ENST00000446778.1
glioblastoma amplified sequence
chr3_+_186435137 4.04 ENST00000447445.1
kininogen 1
chr22_-_29711704 4.01 ENST00000216101.6
RAS-like, family 10, member A
chr17_-_29624343 3.94 ENST00000247271.4
oligodendrocyte myelin glycoprotein
chr7_-_138458781 3.90 ENST00000393054.1
ATPase, H+ transporting, lysosomal V0 subunit a4
chr19_-_36643329 3.89 ENST00000589154.1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr7_+_35756186 3.82 ENST00000430518.1
AC018647.3
chr3_-_50605077 3.81 ENST00000426034.1
ENST00000441239.1
chromosome 3 open reading frame 18
chr16_+_6069072 3.79 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_+_126984710 3.78 ENST00000379445.3
cortexin 3
chr5_+_218356 3.76 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr11_+_34938119 3.71 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
pyruvate dehydrogenase complex, component X
chr8_+_136469684 3.69 ENST00000355849.5
KH domain containing, RNA binding, signal transduction associated 3
chr8_+_86376081 3.66 ENST00000285379.5
carbonic anhydrase II
chr15_+_78441663 3.62 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
isocitrate dehydrogenase 3 (NAD+) alpha
chr11_-_132813566 3.62 ENST00000331898.7
opioid binding protein/cell adhesion molecule-like
chr7_-_44180673 3.61 ENST00000457314.1
ENST00000447951.1
ENST00000431007.1
myosin, light chain 7, regulatory
chr14_-_35183755 3.61 ENST00000555765.1
cofilin 2 (muscle)
chr17_-_1553346 3.61 ENST00000301336.6
Rab interacting lysosomal protein
chr3_+_179322481 3.60 ENST00000259037.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr6_+_53948221 3.57 ENST00000460844.2
muscular LMNA-interacting protein
chr16_+_57481349 3.57 ENST00000262507.6
ENST00000565964.1
coenzyme Q9
chr3_+_179322573 3.56 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr16_+_6069664 3.55 ENST00000422070.4
RNA binding protein, fox-1 homolog (C. elegans) 1
chr8_-_100905850 3.55 ENST00000520271.1
ENST00000522940.1
ENST00000523016.1
ENST00000517682.2
ENST00000297564.2
cytochrome c oxidase subunit VIc
chr3_-_108672609 3.54 ENST00000393963.3
ENST00000471108.1
guanylate cyclase activator 1C
chr11_-_47470703 3.52 ENST00000298854.2
receptor-associated protein of the synapse
chr11_-_34379546 3.52 ENST00000435224.2
ankyrin repeat and BTB (POZ) domain containing 2
chr16_-_19896832 3.50 ENST00000537135.1
ENST00000564449.1
G protein-coupled receptor, family C, group 5, member B
chr19_+_16771936 3.48 ENST00000187762.2
ENST00000599479.1
transmembrane protein 38A
chr18_-_48351743 3.45 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
maestro
chr3_-_42845951 3.43 ENST00000418900.2
ENST00000430190.1
HIG1 hypoxia inducible domain family, member 1A
chr21_-_27107344 3.40 ENST00000457143.2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr11_-_1783633 3.38 ENST00000367196.3
cathepsin D
chr7_-_44180884 3.37 ENST00000458240.1
ENST00000223364.3
myosin, light chain 7, regulatory
chr10_+_81107271 3.37 ENST00000448165.1
peptidylprolyl isomerase F
chr22_+_42372764 3.34 ENST00000396426.3
ENST00000406029.1
septin 3
chr12_+_6644443 3.33 ENST00000396858.1
glyceraldehyde-3-phosphate dehydrogenase
chr5_+_113391696 3.33 ENST00000512927.1
RP11-371M22.1
chr6_+_53948328 3.32 ENST00000370876.2
muscular LMNA-interacting protein
chr8_+_125551338 3.29 ENST00000276689.3
ENST00000518008.1
ENST00000522532.1
ENST00000517367.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
chr21_-_27107198 3.29 ENST00000400094.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr9_-_130889990 3.27 ENST00000449878.1
prostaglandin E synthase 2
chr3_-_183735651 3.27 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr2_+_86426478 3.24 ENST00000254644.8
ENST00000605125.1
ENST00000337109.4
ENST00000409180.1
mitochondrial ribosomal protein L35
chr2_-_74374995 3.22 ENST00000295326.4
bolA family member 3
chr21_-_27107283 3.20 ENST00000284971.3
ENST00000400099.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr17_+_37821593 3.19 ENST00000578283.1
titin-cap
chr16_-_19897455 3.18 ENST00000568214.1
ENST00000569479.1
G protein-coupled receptor, family C, group 5, member B
chr8_-_110704014 3.17 ENST00000529190.1
ENST00000422135.1
ENST00000419099.1
syntabulin (syntaxin-interacting)
chr14_-_35183886 3.17 ENST00000298159.6
cofilin 2 (muscle)
chr7_-_92848858 3.16 ENST00000440868.1
HEPACAM family member 2
chr9_+_133978190 3.16 ENST00000372312.3
allograft inflammatory factor 1-like
chr20_+_13765596 3.15 ENST00000378106.5
ENST00000463598.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
chr1_+_203096831 3.14 ENST00000337894.4
adenosine A1 receptor
chr8_-_100905363 3.12 ENST00000524245.1
cytochrome c oxidase subunit VIc
chr7_-_92848878 3.12 ENST00000341723.4
HEPACAM family member 2
chr16_+_58533951 3.07 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG family member 4
chr4_+_30721968 3.06 ENST00000361762.2
protocadherin 7
chr10_-_97200772 3.05 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
sorbin and SH3 domain containing 1
chr10_+_81107216 3.03 ENST00000394579.3
ENST00000225174.3
peptidylprolyl isomerase F
chr7_-_10979750 3.00 ENST00000339600.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr12_+_121163602 2.99 ENST00000411593.2
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr8_+_67405755 2.99 ENST00000521495.1
chromosome 8 open reading frame 46
chr15_+_43809797 2.98 ENST00000399453.1
ENST00000300231.5
microtubule-associated protein 1A
chr10_+_60028818 2.97 ENST00000333926.5
CDGSH iron sulfur domain 1
chr2_+_172950227 2.96 ENST00000341900.6
distal-less homeobox 1
chr7_+_94536898 2.96 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
protein phosphatase 1, regulatory subunit 9A
chr3_-_108672742 2.93 ENST00000261047.3
guanylate cyclase activator 1C
chr22_+_46546494 2.92 ENST00000396000.2
ENST00000262735.5
ENST00000420804.1
peroxisome proliferator-activated receptor alpha
chr10_+_116853091 2.90 ENST00000526946.1
attractin-like 1
chr16_-_3767551 2.88 ENST00000246957.5
TNF receptor-associated protein 1
chr8_+_67405794 2.87 ENST00000522977.1
ENST00000480005.1
chromosome 8 open reading frame 46
chr15_+_63050785 2.86 ENST00000472902.1
talin 2
chr20_-_48099182 2.86 ENST00000371741.4
potassium voltage-gated channel, Shab-related subfamily, member 1
chr1_-_151798546 2.85 ENST00000356728.6
RAR-related orphan receptor C
chr15_+_43885799 2.84 ENST00000449946.1
ENST00000417289.1
creatine kinase, mitochondrial 1B
chr19_+_18726786 2.84 ENST00000594709.1
transmembrane protein 59-like
chr9_-_32573130 2.83 ENST00000350021.2
ENST00000379847.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chrX_-_46187069 2.81 ENST00000446884.1
RP1-30G7.2
chr4_+_44680429 2.80 ENST00000281543.5
GUF1 GTPase homolog (S. cerevisiae)
chr9_-_35685452 2.78 ENST00000607559.1
tropomyosin 2 (beta)
chr2_+_115822233 2.77 ENST00000393146.2
dipeptidyl-peptidase 10 (non-functional)
chr2_-_106054952 2.77 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
four and a half LIM domains 2
chr7_+_35756092 2.75 ENST00000458087.3
AC018647.3
chr15_+_59730348 2.75 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
family with sequence similarity 81, member A
chr1_-_17380630 2.69 ENST00000375499.3
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr4_+_41614909 2.66 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr8_-_100905925 2.66 ENST00000518171.1
cytochrome c oxidase subunit VIc
chr14_-_21490958 2.65 ENST00000554104.1
NDRG family member 2
chr1_-_31661000 2.65 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
Na+/K+ transporting ATPase interacting 1
chr17_-_2615031 2.65 ENST00000576885.1
ENST00000574426.2
clustered mitochondria (cluA/CLU1) homolog
chr7_+_94536514 2.64 ENST00000413325.1
protein phosphatase 1, regulatory subunit 9A
chr15_-_77988485 2.64 ENST00000561030.1
leucine rich repeat and Ig domain containing 1
chr17_+_34058639 2.62 ENST00000268864.3
RAS-like, family 10, member B
chr16_-_58768177 2.61 ENST00000434819.2
ENST00000245206.5
glutamic-oxaloacetic transaminase 2, mitochondrial
chr16_+_56623433 2.58 ENST00000570176.1
metallothionein 3
chr10_-_21186144 2.58 ENST00000377119.1
nebulette
chr7_+_56032652 2.58 ENST00000437587.1
glioblastoma amplified sequence
chr5_-_176056974 2.54 ENST00000510387.1
ENST00000506696.1
synuclein, beta
chr2_+_98262497 2.54 ENST00000258424.2
cytochrome c oxidase subunit Vb
chr16_-_3767506 2.54 ENST00000538171.1
TNF receptor-associated protein 1
chr1_+_228395755 2.54 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr11_-_131533462 2.54 ENST00000416725.1
AP003039.3
chr1_+_165600436 2.53 ENST00000367888.4
ENST00000367885.1
ENST00000367884.2
microsomal glutathione S-transferase 3
chr22_-_39239987 2.53 ENST00000333039.2
neuronal pentraxin receptor
chr5_-_148033726 2.53 ENST00000354217.2
ENST00000314512.6
ENST00000362016.2
5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
chr19_+_19322758 2.53 ENST00000252575.6
neurocan
chrX_+_103031758 2.52 ENST00000303958.2
ENST00000361621.2
proteolipid protein 1
chr8_+_55047763 2.52 ENST00000260102.4
ENST00000519831.1
mitochondrial ribosomal protein L15
chrX_-_154255143 2.52 ENST00000453950.1
ENST00000423959.1
coagulation factor VIII, procoagulant component
chr14_-_102976135 2.50 ENST00000560748.1
ankyrin repeat domain 9
chr1_+_42846443 2.49 ENST00000410070.2
ENST00000431473.3
ribosomal modification protein rimK-like family member A
chr12_+_10366223 2.48 ENST00000545290.1
GABA(A) receptor-associated protein like 1
chrX_+_103031421 2.47 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
proteolipid protein 1
chr19_+_35783028 2.47 ENST00000600291.1
ENST00000392213.3
myelin associated glycoprotein
chr11_+_12766583 2.45 ENST00000361985.2
TEA domain family member 1 (SV40 transcriptional enhancer factor)

Network of associatons between targets according to the STRING database.

First level regulatory network of ESRRB_ESRRG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
11.4 45.6 GO:1903060 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
4.3 12.8 GO:0006106 fumarate metabolic process(GO:0006106)
3.5 24.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
2.6 44.9 GO:0006600 creatine metabolic process(GO:0006600)
2.4 7.3 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
2.2 8.7 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
2.1 6.4 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
1.8 5.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.8 12.6 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
1.7 5.0 GO:0032242 regulation of nucleoside transport(GO:0032242)
1.6 4.8 GO:0050894 determination of affect(GO:0050894)
1.5 4.5 GO:1990709 maintenance of synapse structure(GO:0099558) presynaptic active zone organization(GO:1990709)
1.5 26.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.4 5.6 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
1.4 1.4 GO:0006533 aspartate catabolic process(GO:0006533)
1.4 5.4 GO:0009386 translational attenuation(GO:0009386)
1.3 5.0 GO:1903028 positive regulation of opsonization(GO:1903028)
1.2 3.7 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
1.2 3.7 GO:0042938 dipeptide transport(GO:0042938)
1.2 3.6 GO:0070676 intralumenal vesicle formation(GO:0070676)
1.2 3.6 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
1.2 8.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
1.2 9.3 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
1.1 4.5 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
1.1 11.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
1.1 37.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
1.0 4.1 GO:0006781 succinyl-CoA pathway(GO:0006781)
1.0 3.0 GO:0021893 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
1.0 21.5 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.9 7.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.9 2.7 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.9 2.6 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.9 2.6 GO:2000374 cadmium ion homeostasis(GO:0055073) regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
0.8 7.9 GO:0006105 succinate metabolic process(GO:0006105)
0.7 1.4 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.7 3.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.7 7.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.6 8.1 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.6 3.7 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.6 13.4 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.6 2.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.6 2.9 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.6 8.9 GO:0030043 actin filament fragmentation(GO:0030043)
0.5 1.6 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.5 40.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.5 6.3 GO:0071321 cellular response to cGMP(GO:0071321)
0.5 1.6 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.5 1.6 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.5 5.0 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.5 6.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.5 2.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.5 2.9 GO:0035900 response to isolation stress(GO:0035900)
0.5 2.3 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.5 10.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.5 3.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.4 18.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.4 7.1 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.4 1.3 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.4 2.5 GO:0036309 protein localization to M-band(GO:0036309)
0.4 0.8 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.4 5.9 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.4 1.6 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.4 1.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.4 1.9 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.4 0.8 GO:0009644 response to high light intensity(GO:0009644)
0.4 10.8 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.4 1.9 GO:0017055 female courtship behavior(GO:0008050) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.4 1.9 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.4 10.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.4 4.7 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.4 2.2 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.4 2.5 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.3 10.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.3 1.0 GO:0035623 renal glucose absorption(GO:0035623)
0.3 4.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.3 7.5 GO:0071420 cellular response to histamine(GO:0071420)
0.3 7.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 2.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 26.8 GO:0015701 bicarbonate transport(GO:0015701)
0.3 1.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.3 2.8 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.3 10.1 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.3 0.6 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.3 1.5 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.3 2.4 GO:0023021 termination of signal transduction(GO:0023021)
0.3 4.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.3 1.1 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 5.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.3 2.2 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.3 1.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.3 0.8 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.3 1.6 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.3 1.3 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3 0.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.3 1.8 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.3 1.0 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2 1.7 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.2 1.0 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 4.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 6.7 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.2 2.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.2 3.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.2 10.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 7.6 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.2 2.2 GO:0042407 cristae formation(GO:0042407)
0.2 1.5 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.2 10.8 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.2 3.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 3.7 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.2 1.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.2 1.3 GO:0097327 response to antineoplastic agent(GO:0097327)
0.2 4.9 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 4.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 1.2 GO:0019427 acetate metabolic process(GO:0006083) acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.2 0.6 GO:0015709 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.2 5.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 2.6 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 0.6 GO:0018012 N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.2 4.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 1.0 GO:1990535 neuron projection maintenance(GO:1990535)
0.2 2.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.2 0.6 GO:0033159 positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.2 1.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 1.2 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.2 4.5 GO:0006119 oxidative phosphorylation(GO:0006119)
0.2 1.0 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 3.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 2.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.9 GO:0097286 iron ion import(GO:0097286)
0.2 1.6 GO:0030242 pexophagy(GO:0030242)
0.2 1.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 1.4 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.2 1.9 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 1.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 1.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 3.1 GO:0006089 lactate metabolic process(GO:0006089)
0.2 0.6 GO:0009822 alkaloid catabolic process(GO:0009822)
0.2 0.6 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.2 5.1 GO:0032098 regulation of appetite(GO:0032098)
0.2 0.9 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 1.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 1.8 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.6 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 2.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 1.0 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 12.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 3.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 0.4 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.7 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 9.1 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 2.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 0.5 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.1 4.7 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 1.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.5 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 2.5 GO:0006853 carnitine shuttle(GO:0006853)
0.1 6.1 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 1.4 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.1 1.8 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 9.9 GO:0008038 neuron recognition(GO:0008038)
0.1 10.8 GO:0014047 glutamate secretion(GO:0014047)
0.1 2.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 1.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 2.1 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1 5.9 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 2.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 1.8 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.1 2.3 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 9.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 3.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.8 GO:0033216 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 1.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 2.9 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 1.5 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 2.5 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.1 0.4 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.9 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 1.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 3.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 2.5 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.4 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 1.6 GO:0009790 embryo development(GO:0009790)
0.1 1.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 3.5 GO:0097237 cellular response to toxic substance(GO:0097237)
0.1 0.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.0 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 3.9 GO:0010107 potassium ion import(GO:0010107)
0.1 7.4 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.1 0.5 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 2.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.0 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 9.8 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.7 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.6 GO:0051105 regulation of DNA ligation(GO:0051105)
0.1 0.6 GO:0060356 tryptophan transport(GO:0015827) leucine import(GO:0060356)
0.1 2.0 GO:0014733 regulation of skeletal muscle adaptation(GO:0014733)
0.1 0.8 GO:0097338 response to clozapine(GO:0097338)
0.1 2.0 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 1.2 GO:0030157 pancreatic juice secretion(GO:0030157)
0.1 7.5 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 0.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.3 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 4.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 0.5 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 4.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.2 GO:0061304 cerebellum vasculature development(GO:0061300) retinal blood vessel morphogenesis(GO:0061304)
0.1 0.8 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 1.9 GO:0006833 water transport(GO:0006833)
0.1 1.3 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.1 9.0 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.1 GO:0015677 copper ion import(GO:0015677)
0.1 0.6 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 2.2 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.1 1.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 1.8 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 5.4 GO:0005977 glycogen metabolic process(GO:0005977)
0.1 0.9 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 3.1 GO:0045333 cellular respiration(GO:0045333)
0.1 1.8 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.1 2.5 GO:0042417 dopamine metabolic process(GO:0042417)
0.1 2.4 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 1.3 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.1 4.1 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.1 1.4 GO:0030252 growth hormone secretion(GO:0030252)
0.1 0.7 GO:0048511 rhythmic process(GO:0048511)
0.1 1.1 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 1.0 GO:0007097 nuclear migration(GO:0007097)
0.0 1.8 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 1.4 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.8 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.8 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.1 GO:0031214 biomineral tissue development(GO:0031214)
0.0 1.2 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 2.2 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 2.6 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 3.3 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.5 GO:0006477 protein sulfation(GO:0006477)
0.0 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 1.1 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 1.9 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 2.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 1.8 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.2 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 1.4 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.9 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.7 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 2.0 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.3 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 1.0 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 2.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 2.9 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.6 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.4 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139)
0.0 0.3 GO:1901991 negative regulation of mitotic cell cycle phase transition(GO:1901991) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.4 GO:0034205 beta-amyloid formation(GO:0034205)
0.0 1.3 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 1.2 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 3.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 2.5 GO:0008652 cellular amino acid biosynthetic process(GO:0008652)
0.0 0.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.3 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 1.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0010226 response to lithium ion(GO:0010226)
0.0 1.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.5 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.3 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 1.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.0 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 4.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 1.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 2.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.5 GO:0035094 response to nicotine(GO:0035094)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 7.7 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.1 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 1.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.5 GO:0006301 postreplication repair(GO:0006301)
0.0 0.6 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.6 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.1 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0005745 m-AAA complex(GO:0005745)
2.6 15.3 GO:1990584 cardiac Troponin complex(GO:1990584)
2.4 7.1 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
2.1 6.3 GO:0098855 HCN channel complex(GO:0098855)
1.5 5.9 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
1.4 16.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.3 16.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.1 39.4 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
1.0 6.0 GO:0070470 plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470)
0.9 26.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.8 11.0 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.8 11.3 GO:0097512 cardiac myofibril(GO:0097512)
0.8 5.6 GO:0044326 dendritic spine neck(GO:0044326)
0.7 5.5 GO:0097452 GAIT complex(GO:0097452)
0.6 2.6 GO:0097450 astrocyte end-foot(GO:0097450)
0.6 2.5 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.6 2.3 GO:1902912 pyruvate kinase complex(GO:1902912)
0.6 4.0 GO:0005899 insulin receptor complex(GO:0005899)
0.5 4.2 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.5 4.5 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.5 4.8 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.4 3.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.4 7.3 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.4 2.4 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.4 28.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.4 14.5 GO:0070469 respiratory chain(GO:0070469)
0.4 3.1 GO:1990635 proximal dendrite(GO:1990635)
0.4 1.9 GO:0042584 chromaffin granule membrane(GO:0042584)
0.4 3.7 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.4 3.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.4 9.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 1.0 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.3 1.7 GO:0005879 axonemal microtubule(GO:0005879)
0.3 10.9 GO:0031143 pseudopodium(GO:0031143)
0.3 3.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.3 4.3 GO:0032426 stereocilium tip(GO:0032426)
0.3 1.6 GO:1990246 uniplex complex(GO:1990246)
0.2 1.9 GO:0061617 MICOS complex(GO:0061617)
0.2 2.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 1.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 0.5 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.2 15.4 GO:0048786 presynaptic active zone(GO:0048786)
0.2 0.7 GO:0044305 calyx of Held(GO:0044305)
0.2 1.6 GO:1990130 Iml1 complex(GO:1990130)
0.2 13.6 GO:0031430 M band(GO:0031430)
0.2 7.0 GO:0031672 A band(GO:0031672)
0.2 2.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 4.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 5.9 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.2 2.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 4.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 7.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 3.2 GO:0097433 dense body(GO:0097433)
0.2 11.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 0.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 6.4 GO:0032590 dendrite membrane(GO:0032590)
0.2 84.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 0.5 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 1.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.8 GO:1990393 3M complex(GO:1990393)
0.1 3.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 7.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 10.8 GO:0043198 dendritic shaft(GO:0043198)
0.1 41.2 GO:0030016 myofibril(GO:0030016)
0.1 2.7 GO:0097440 apical dendrite(GO:0097440)
0.1 1.0 GO:0045179 apical cortex(GO:0045179)
0.1 30.1 GO:0043209 myelin sheath(GO:0043209)
0.1 1.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 2.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 13.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 5.2 GO:0034707 chloride channel complex(GO:0034707)
0.1 2.0 GO:0005581 collagen trimer(GO:0005581)
0.1 4.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 29.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 20.8 GO:0030426 growth cone(GO:0030426)
0.1 2.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 3.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 7.1 GO:0005811 lipid particle(GO:0005811)
0.1 4.4 GO:0016459 myosin complex(GO:0016459)
0.1 2.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.1 GO:0044753 amphisome(GO:0044753)
0.1 0.9 GO:0043194 axon initial segment(GO:0043194)
0.1 2.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.7 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 5.1 GO:0005884 actin filament(GO:0005884)
0.1 0.3 GO:1990037 Lewy body core(GO:1990037)
0.1 9.0 GO:0043202 lysosomal lumen(GO:0043202)
0.1 11.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 46.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 3.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 3.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 4.8 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0 3.0 GO:0016234 inclusion body(GO:0016234)
0.0 1.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 5.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 5.9 GO:0030496 midbody(GO:0030496)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.8 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 6.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 4.3 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 10.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 3.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 3.9 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 4.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0060170 ciliary membrane(GO:0060170)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 44.9 GO:0004111 creatine kinase activity(GO:0004111)
2.9 8.6 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
2.5 7.5 GO:0005298 proline:sodium symporter activity(GO:0005298)
2.4 16.7 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
2.3 9.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
2.0 11.9 GO:0051373 FATZ binding(GO:0051373)
2.0 5.9 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
1.9 15.3 GO:0030172 troponin C binding(GO:0030172)
1.6 4.8 GO:0031877 somatostatin receptor binding(GO:0031877)
1.4 5.5 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.4 4.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
1.3 9.1 GO:0043532 angiostatin binding(GO:0043532)
1.3 6.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
1.0 8.2 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.0 3.1 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
1.0 24.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.0 5.0 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.9 3.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.8 5.9 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.8 9.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.8 24.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.8 4.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.8 4.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.7 4.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.7 10.0 GO:0052658 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.7 5.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.7 3.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.6 7.1 GO:0033691 sialic acid binding(GO:0033691)
0.6 2.5 GO:0005199 structural constituent of cell wall(GO:0005199)
0.6 2.5 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.6 4.8 GO:0050682 AF-2 domain binding(GO:0050682)
0.6 2.3 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.6 4.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.6 20.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.6 2.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.5 2.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.5 1.6 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.5 18.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.5 2.5 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.5 12.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.5 29.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 1.9 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.5 2.3 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.5 1.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.5 3.7 GO:0004064 arylesterase activity(GO:0004064)
0.4 1.3 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.4 2.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.4 3.7 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.4 6.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.4 4.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 2.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 3.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.4 1.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.4 16.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.4 1.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.3 9.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.3 4.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 6.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 2.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 2.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 2.4 GO:0004771 sterol esterase activity(GO:0004771)
0.3 5.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.3 8.1 GO:0044548 S100 protein binding(GO:0044548)
0.3 1.7 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.3 1.1 GO:0032427 GBD domain binding(GO:0032427)
0.3 3.6 GO:0015288 porin activity(GO:0015288)
0.3 3.6 GO:0051525 NFAT protein binding(GO:0051525)
0.3 1.9 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.3 1.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.3 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.3 5.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 2.6 GO:0046870 cadmium ion binding(GO:0046870)
0.3 4.9 GO:0030957 Tat protein binding(GO:0030957)
0.3 1.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 7.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 6.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 2.9 GO:0008142 oxysterol binding(GO:0008142)
0.2 5.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 0.9 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 0.7 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.2 0.9 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 0.9 GO:0008431 vitamin E binding(GO:0008431)
0.2 2.0 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 0.6 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.2 1.8 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.2 1.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 3.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 1.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 0.6 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.2 1.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 0.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 2.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 1.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 1.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 14.9 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.2 0.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 6.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 5.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 2.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.9 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2 2.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.0 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 2.3 GO:1903136 cuprous ion binding(GO:1903136)
0.2 3.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 1.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.2 0.6 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.2 1.5 GO:0046790 complement component C1q binding(GO:0001849) virion binding(GO:0046790)
0.2 0.9 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.2 1.2 GO:0035473 lipase binding(GO:0035473)
0.2 1.5 GO:0004985 opioid receptor activity(GO:0004985)
0.2 2.0 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.2 0.6 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 1.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 3.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 1.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.6 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.7 GO:0004461 lactose synthase activity(GO:0004461)
0.1 4.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.6 GO:0001727 lipid kinase activity(GO:0001727)
0.1 1.4 GO:0004046 aminoacylase activity(GO:0004046)
0.1 2.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 4.5 GO:0031489 myosin V binding(GO:0031489)
0.1 0.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 2.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.9 GO:0015250 water channel activity(GO:0015250)
0.1 2.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.5 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 7.6 GO:0043531 ADP binding(GO:0043531)
0.1 1.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 4.0 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.0 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 3.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.8 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 2.9 GO:0031005 filamin binding(GO:0031005)
0.1 0.5 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 5.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 4.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.0 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.3 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 15.7 GO:0051082 unfolded protein binding(GO:0051082)
0.1 2.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 2.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 4.9 GO:0005158 insulin receptor binding(GO:0005158)
0.1 5.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.8 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.1 2.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 2.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.8 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 8.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.7 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.5 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.6 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.4 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 1.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.1 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 2.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 3.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 3.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 4.2 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 1.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 1.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.8 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 17.9 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 2.4 GO:0042805 actinin binding(GO:0042805)
0.0 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 14.4 GO:0051015 actin filament binding(GO:0051015)
0.0 2.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 6.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 2.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 1.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 5.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 7.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 4.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.6 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.9 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 4.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.9 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.2 GO:0005549 odorant binding(GO:0005549)
0.0 2.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.6 GO:0048018 receptor agonist activity(GO:0048018)
0.0 2.2 GO:0051117 ATPase binding(GO:0051117)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 1.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 2.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 5.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 2.2 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 3.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.7 GO:0015405 primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.8 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 5.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 2.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 7.7 PID CONE PATHWAY Visual signal transduction: Cones
0.2 7.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 9.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 20.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 22.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 4.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 5.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 1.6 PID ALK2 PATHWAY ALK2 signaling events
0.1 4.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 3.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 9.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 3.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 3.3 PID IFNG PATHWAY IFN-gamma pathway
0.1 7.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 5.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 2.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 1.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.3 PID INSULIN PATHWAY Insulin Pathway
0.0 3.7 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 5.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.8 ST GA13 PATHWAY G alpha 13 Pathway
0.0 3.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.8 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 26.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.7 63.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.5 31.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.5 34.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 11.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.4 10.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.4 9.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.3 1.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.3 6.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 4.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.3 16.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 10.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 5.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.3 4.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.2 7.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 3.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 2.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 7.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 31.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 9.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 7.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 63.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 2.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 6.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 8.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 3.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 6.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 4.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 3.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 12.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 3.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 0.6 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 0.8 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 4.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 2.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 5.5 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 1.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 4.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.9 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 2.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 4.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 3.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.5 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 2.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 8.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 2.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 5.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 2.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 4.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 4.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 2.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 4.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 3.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.8 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions