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Illumina Body Map 2, young vs old

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Results for FIGLA

Z-value: 0.60

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Transcription factors associated with FIGLA

Gene Symbol Gene ID Gene Info
FIGLA
ENSG00000183733.6 folliculogenesis specific bHLH transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FIGLAhg19_v2_chr2_-_71017775_710177750.441.2e-02Click!

Activity profile of FIGLA motif

Sorted Z-values of FIGLA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_39258461 4.74 ENST00000440582.1
KRTAP4-16P
keratin associated protein 4-16, pseudogene
chr2_-_152590946 3.14 ENST00000172853.10
NEB
nebulin
chr16_-_11375179 3.03 ENST00000312511.3
PRM1
protamine 1
chr19_+_50936142 2.92 ENST00000357701.5
MYBPC2
myosin binding protein C, fast type
chr7_-_27196267 2.50 ENST00000242159.3
HOXA7
homeobox A7
chr17_-_39324424 2.37 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr1_-_201391149 2.33 ENST00000555948.1
ENST00000556362.1
TNNI1
troponin I type 1 (skeletal, slow)
chr17_-_7165662 2.20 ENST00000571881.2
ENST00000360325.7
CLDN7
claudin 7
chr17_+_48133459 2.15 ENST00000320031.8
ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr3_-_50383096 2.06 ENST00000442887.1
ENST00000360165.3
ZMYND10
zinc finger, MYND-type containing 10
chr4_-_177116772 2.04 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr2_-_42160486 2.03 ENST00000427054.1
AC104654.2
AC104654.2
chr12_+_6419877 2.02 ENST00000536531.1
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr2_-_152590982 1.98 ENST00000409198.1
ENST00000397345.3
ENST00000427231.2
NEB
nebulin
chr17_+_48133330 1.92 ENST00000544892.1
ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr6_-_39197226 1.91 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr3_+_52454971 1.87 ENST00000465863.1
PHF7
PHD finger protein 7
chr1_-_183622442 1.83 ENST00000308641.4
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr2_+_176987088 1.80 ENST00000249499.6
HOXD9
homeobox D9
chr17_-_46035187 1.75 ENST00000300557.2
PRR15L
proline rich 15-like
chr6_-_19804973 1.74 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
RP4-625H18.2
chr1_-_115238207 1.59 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
AMPD1
adenosine monophosphate deaminase 1
chr15_+_45722727 1.58 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48
chromosome 15 open reading frame 48
chr12_-_13248562 1.56 ENST00000457134.2
ENST00000537302.1
GSG1
germ cell associated 1
chr17_-_39254391 1.53 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chrX_-_11445856 1.49 ENST00000380736.1
ARHGAP6
Rho GTPase activating protein 6
chr16_+_30383613 1.45 ENST00000568749.1
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr2_-_75788038 1.45 ENST00000393913.3
ENST00000410113.1
EVA1A
eva-1 homolog A (C. elegans)
chr22_+_22988816 1.43 ENST00000480559.1
ENST00000448514.1
GGTLC2
gamma-glutamyltransferase light chain 2
chr6_-_100912785 1.41 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr20_+_30407151 1.40 ENST00000375985.4
MYLK2
myosin light chain kinase 2
chr20_+_30407105 1.36 ENST00000375994.2
MYLK2
myosin light chain kinase 2
chr11_-_117698787 1.36 ENST00000260287.2
FXYD2
FXYD domain containing ion transport regulator 2
chr12_-_13248732 1.34 ENST00000396302.3
GSG1
germ cell associated 1
chr7_-_92855762 1.31 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr17_+_73521763 1.29 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr8_-_49834299 1.29 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr5_-_54281491 1.28 ENST00000381405.4
ESM1
endothelial cell-specific molecule 1
chr4_+_106816592 1.26 ENST00000379987.2
ENST00000453617.2
ENST00000427316.2
ENST00000514622.1
ENST00000305572.8
NPNT
nephronectin
chr17_-_39280419 1.26 ENST00000394014.1
KRTAP4-12
keratin associated protein 4-12
chr17_+_42015654 1.26 ENST00000565120.1
RP11-527L4.2
Uncharacterized protein
chr8_-_49833978 1.23 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr11_+_111789580 1.22 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr1_-_171621815 1.20 ENST00000037502.6
MYOC
myocilin, trabecular meshwork inducible glucocorticoid response
chr12_-_13248705 1.19 ENST00000396310.2
GSG1
germ cell associated 1
chr18_+_77439775 1.18 ENST00000299543.7
ENST00000075430.7
CTDP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chrX_+_13587712 1.17 ENST00000361306.1
ENST00000380602.3
EGFL6
EGF-like-domain, multiple 6
chr7_+_130020180 1.17 ENST00000481342.1
ENST00000011292.3
ENST00000604896.1
CPA1
carboxypeptidase A1 (pancreatic)
chr5_-_54281407 1.17 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr12_-_91348949 1.16 ENST00000358859.2
CCER1
coiled-coil glutamate-rich protein 1
chr3_+_140396881 1.16 ENST00000286349.3
TRIM42
tripartite motif containing 42
chr7_+_140103842 1.16 ENST00000495590.1
ENST00000275874.5
ENST00000537763.1
RAB19
RAB19, member RAS oncogene family
chr5_+_34656529 1.13 ENST00000513974.1
ENST00000512629.1
RAI14
retinoic acid induced 14
chr6_+_22569784 1.13 ENST00000510882.2
HDGFL1
hepatoma derived growth factor-like 1
chr11_-_117698765 1.12 ENST00000532119.1
FXYD2
FXYD domain containing ion transport regulator 2
chr4_+_106816644 1.11 ENST00000506666.1
ENST00000503451.1
NPNT
nephronectin
chr2_-_227050079 1.10 ENST00000423838.1
AC068138.1
AC068138.1
chr6_-_10419871 1.10 ENST00000319516.4
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_+_44184653 1.09 ENST00000573382.2
ENST00000576476.1
RP1-302G2.5
RP1-302G2.5
chr19_+_6464243 1.09 ENST00000600229.1
ENST00000356762.3
CRB3
crumbs homolog 3 (Drosophila)
chr16_+_610407 1.07 ENST00000409413.3
C16orf11
chromosome 16 open reading frame 11
chr5_+_34656569 1.07 ENST00000428746.2
RAI14
retinoic acid induced 14
chr2_+_233390890 1.07 ENST00000258385.3
ENST00000536614.1
ENST00000457943.2
CHRND
cholinergic receptor, nicotinic, delta (muscle)
chr19_-_46272106 1.06 ENST00000560168.1
SIX5
SIX homeobox 5
chr17_+_8243154 1.06 ENST00000328248.2
ENST00000584943.1
ODF4
outer dense fiber of sperm tails 4
chr8_-_144512576 1.06 ENST00000333480.2
MAFA
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
chr1_+_183155373 1.05 ENST00000493293.1
ENST00000264144.4
LAMC2
laminin, gamma 2
chr2_+_78143006 1.05 ENST00000443419.1
AC073628.1
AC073628.1
chr2_+_177001685 1.05 ENST00000432796.2
HOXD3
homeobox D3
chr6_-_19804877 1.04 ENST00000447250.1
RP4-625H18.2
RP4-625H18.2
chr9_-_116861337 1.03 ENST00000374118.3
KIF12
kinesin family member 12
chr12_+_50497784 1.01 ENST00000548814.1
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr17_-_46262541 0.98 ENST00000579336.1
SKAP1
src kinase associated phosphoprotein 1
chr3_-_49722523 0.97 ENST00000448220.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr6_+_7107830 0.97 ENST00000379933.3
RREB1
ras responsive element binding protein 1
chr17_-_39306054 0.96 ENST00000343246.4
KRTAP4-5
keratin associated protein 4-5
chr20_+_44441304 0.95 ENST00000352551.5
UBE2C
ubiquitin-conjugating enzyme E2C
chr20_-_22566089 0.94 ENST00000377115.4
FOXA2
forkhead box A2
chr2_-_85890569 0.94 ENST00000494165.1
SFTPB
surfactant protein B
chr2_+_46524537 0.94 ENST00000263734.3
EPAS1
endothelial PAS domain protein 1
chr5_-_16936340 0.94 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr6_-_31697255 0.93 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr6_+_22569678 0.93 ENST00000230012.3
HDGFL1
hepatoma derived growth factor-like 1
chr19_+_35739280 0.92 ENST00000602122.1
LSR
lipolysis stimulated lipoprotein receptor
chrX_+_128872998 0.92 ENST00000371106.3
XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr17_-_46657473 0.92 ENST00000332503.5
HOXB4
homeobox B4
chr16_+_4845379 0.91 ENST00000588606.1
ENST00000586005.1
SMIM22
small integral membrane protein 22
chr19_+_35739782 0.91 ENST00000347609.4
LSR
lipolysis stimulated lipoprotein receptor
chr17_-_39296739 0.89 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr12_-_52585765 0.85 ENST00000313234.5
ENST00000394815.2
KRT80
keratin 80
chr6_+_7108210 0.85 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
RREB1
ras responsive element binding protein 1
chr2_-_175629135 0.85 ENST00000409542.1
ENST00000409219.1
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr5_+_68788594 0.85 ENST00000396442.2
ENST00000380766.2
OCLN
occludin
chr2_+_233390863 0.84 ENST00000449596.1
ENST00000543200.1
CHRND
cholinergic receptor, nicotinic, delta (muscle)
chr20_+_44441215 0.84 ENST00000356455.4
ENST00000405520.1
UBE2C
ubiquitin-conjugating enzyme E2C
chr16_-_57513657 0.83 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
DOK4
docking protein 4
chr5_-_159739532 0.82 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL
cyclin J-like
chr19_+_35739631 0.81 ENST00000602003.1
ENST00000360798.3
ENST00000354900.3
LSR
lipolysis stimulated lipoprotein receptor
chr19_+_35739597 0.81 ENST00000361790.3
LSR
lipolysis stimulated lipoprotein receptor
chr5_-_159739483 0.81 ENST00000519673.1
ENST00000541762.1
CCNJL
cyclin J-like
chr18_-_45663666 0.80 ENST00000535628.2
ZBTB7C
zinc finger and BTB domain containing 7C
chr7_-_11871815 0.79 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr15_-_53097139 0.79 ENST00000560818.1
RP11-209K10.2
RP11-209K10.2
chr7_+_93535817 0.79 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr16_+_4606347 0.79 ENST00000444310.4
C16orf96
chromosome 16 open reading frame 96
chr15_+_67547113 0.78 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQCH
IQ motif containing H
chrX_+_128872918 0.78 ENST00000371105.3
XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr19_+_14017116 0.77 ENST00000589606.1
CC2D1A
coiled-coil and C2 domain containing 1A
chr8_+_22435762 0.77 ENST00000456545.1
PDLIM2
PDZ and LIM domain 2 (mystique)
chr12_-_53228079 0.77 ENST00000330553.5
KRT79
keratin 79
chr14_-_92413353 0.77 ENST00000556154.1
FBLN5
fibulin 5
chr11_+_47279155 0.75 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr1_+_6615241 0.74 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
TAS1R1
taste receptor, type 1, member 1
chr19_-_4902877 0.73 ENST00000381781.2
ARRDC5
arrestin domain containing 5
chr4_-_76555657 0.73 ENST00000307465.4
CDKL2
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr6_+_7107999 0.72 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr10_+_24755416 0.71 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chrX_-_153775426 0.71 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr19_+_16187085 0.71 ENST00000300933.4
TPM4
tropomyosin 4
chr1_-_156675535 0.70 ENST00000368221.1
CRABP2
cellular retinoic acid binding protein 2
chr14_-_37051798 0.70 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr1_+_22328144 0.70 ENST00000290122.3
ENST00000374663.1
CELA3A
chymotrypsin-like elastase family, member 3A
chr2_-_175629164 0.70 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr2_+_137523086 0.69 ENST00000409968.1
THSD7B
thrombospondin, type I, domain containing 7B
chr10_+_24498060 0.69 ENST00000376454.3
ENST00000376452.3
KIAA1217
KIAA1217
chr16_+_67233412 0.69 ENST00000477898.1
ELMO3
engulfment and cell motility 3
chr1_-_205313304 0.68 ENST00000539253.1
ENST00000607826.1
KLHDC8A
kelch domain containing 8A
chr17_-_31204124 0.68 ENST00000579584.1
ENST00000318217.5
ENST00000583621.1
MYO1D
myosin ID
chr14_-_92413727 0.67 ENST00000267620.10
FBLN5
fibulin 5
chr14_-_92414055 0.67 ENST00000342058.4
FBLN5
fibulin 5
chr11_+_130318869 0.67 ENST00000299164.2
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr12_+_52450298 0.66 ENST00000550582.2
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr9_-_22009241 0.66 ENST00000380142.4
CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr10_+_24497704 0.66 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr11_+_47279248 0.65 ENST00000449369.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr5_+_157098534 0.65 ENST00000409999.3
C5orf52
chromosome 5 open reading frame 52
chr1_-_156675368 0.64 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chr5_+_150406527 0.64 ENST00000520059.1
GPX3
glutathione peroxidase 3 (plasma)
chr7_+_128784712 0.63 ENST00000289407.4
TSPAN33
tetraspanin 33
chr12_-_53242770 0.63 ENST00000304620.4
ENST00000547110.1
KRT78
keratin 78
chr7_-_148725733 0.63 ENST00000286091.4
PDIA4
protein disulfide isomerase family A, member 4
chr4_+_15376165 0.63 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr15_+_67547163 0.62 ENST00000335894.4
IQCH
IQ motif containing H
chr4_-_186456652 0.62 ENST00000284767.5
ENST00000284770.5
PDLIM3
PDZ and LIM domain 3
chr13_-_20767037 0.62 ENST00000382848.4
GJB2
gap junction protein, beta 2, 26kDa
chr8_-_99837856 0.61 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr17_+_39261584 0.60 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr9_-_22009297 0.60 ENST00000276925.6
CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr1_-_150669500 0.60 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr6_+_109169591 0.60 ENST00000368972.3
ENST00000392644.4
ARMC2
armadillo repeat containing 2
chr11_+_71249071 0.60 ENST00000398534.3
KRTAP5-8
keratin associated protein 5-8
chr19_-_18709357 0.59 ENST00000597131.1
CRLF1
cytokine receptor-like factor 1
chrX_-_30326445 0.59 ENST00000378963.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr22_-_50970506 0.59 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr6_-_133055896 0.59 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr8_-_103668114 0.58 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr11_+_27062272 0.58 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr7_-_84816122 0.57 ENST00000444867.1
SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr2_-_28113965 0.57 ENST00000302188.3
RBKS
ribokinase
chr1_-_55352834 0.57 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chr11_+_93754513 0.56 ENST00000315765.9
HEPHL1
hephaestin-like 1
chr4_+_5712898 0.56 ENST00000264956.6
ENST00000382674.2
EVC
Ellis van Creveld syndrome
chr11_-_124632179 0.56 ENST00000278927.5
ENST00000442070.2
ENST00000444566.1
ENST00000435477.1
ESAM
endothelial cell adhesion molecule
chr2_+_220436917 0.56 ENST00000243786.2
INHA
inhibin, alpha
chr11_+_120110863 0.55 ENST00000543440.2
POU2F3
POU class 2 homeobox 3
chr10_-_128975273 0.55 ENST00000424811.2
FAM196A
family with sequence similarity 196, member A
chr19_+_6464502 0.54 ENST00000308243.7
CRB3
crumbs homolog 3 (Drosophila)
chr8_-_144790224 0.54 ENST00000533508.1
ENST00000542437.1
CCDC166
coiled-coil domain containing 166
chr10_-_33625154 0.53 ENST00000265371.4
NRP1
neuropilin 1
chr7_+_75028199 0.53 ENST00000437796.1
TRIM73
tripartite motif containing 73
chr19_+_14017003 0.53 ENST00000318003.7
CC2D1A
coiled-coil and C2 domain containing 1A
chr2_-_28113217 0.53 ENST00000444339.2
RBKS
ribokinase
chr2_+_228029281 0.53 ENST00000396578.3
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr11_+_27062502 0.53 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr4_-_186456766 0.52 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr19_+_16186903 0.51 ENST00000588507.1
TPM4
tropomyosin 4
chr2_-_220436248 0.51 ENST00000265318.4
OBSL1
obscurin-like 1
chr15_-_32162833 0.51 ENST00000560598.1
OTUD7A
OTU domain containing 7A
chr2_+_121493717 0.51 ENST00000418323.1
GLI2
GLI family zinc finger 2
chr11_-_62752455 0.51 ENST00000360421.4
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr6_-_31697563 0.50 ENST00000375789.2
ENST00000416410.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr14_-_81916501 0.49 ENST00000555001.1
RP11-299L17.3
RP11-299L17.3
chr19_-_15590306 0.49 ENST00000292609.4
PGLYRP2
peptidoglycan recognition protein 2
chr2_+_42104692 0.49 ENST00000398796.2
ENST00000442214.1
AC104654.1
AC104654.1
chr17_-_39191107 0.48 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chrX_+_47863734 0.48 ENST00000304355.5
SPACA5
sperm acrosome associated 5
chr1_-_39339777 0.48 ENST00000397572.2
MYCBP
MYC binding protein
chr3_-_49066811 0.48 ENST00000442157.1
ENST00000326739.4
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr11_-_62752162 0.48 ENST00000458333.2
ENST00000421062.2
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr5_+_34656331 0.47 ENST00000265109.3
RAI14
retinoic acid induced 14
chr4_+_5712942 0.47 ENST00000509451.1
EVC
Ellis van Creveld syndrome
chr1_+_10509971 0.47 ENST00000320498.4
CORT
cortistatin
chr17_+_9548845 0.47 ENST00000570475.1
ENST00000285199.7
USP43
ubiquitin specific peptidase 43
chr11_-_62752429 0.46 ENST00000377871.3
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr6_+_18387570 0.46 ENST00000259939.3
RNF144B
ring finger protein 144B
chr19_-_49118067 0.46 ENST00000593772.1
FAM83E
family with sequence similarity 83, member E
chr7_+_12726623 0.45 ENST00000439721.1
ARL4A
ADP-ribosylation factor-like 4A
chr19_-_51456198 0.45 ENST00000594846.1
KLK5
kallikrein-related peptidase 5
chr14_+_75746340 0.44 ENST00000555686.1
ENST00000555672.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr11_+_86511569 0.44 ENST00000441050.1
PRSS23
protease, serine, 23

Network of associatons between targets according to the STRING database.

First level regulatory network of FIGLA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.1 GO:0007525 somatic muscle development(GO:0007525)
0.8 2.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.6 2.5 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.6 2.4 GO:0097195 pilomotor reflex(GO:0097195)
0.6 3.5 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.5 1.4 GO:0097254 renal tubular secretion(GO:0097254)
0.4 1.2 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.4 2.8 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.4 3.5 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.4 1.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.3 1.0 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.3 2.5 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.3 1.4 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 0.9 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2 1.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.2 1.1 GO:0003409 optic cup structural organization(GO:0003409)
0.2 1.8 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.2 1.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 2.5 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.2 0.5 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 0.9 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 0.5 GO:0032824 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.2 2.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 3.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.6 GO:0032264 IMP salvage(GO:0032264)
0.1 0.6 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 2.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.6 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.6 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.1 0.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.7 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 2.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 2.1 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 4.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 1.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.5 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.7 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.9 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.9 GO:0048539 bone marrow development(GO:0048539)
0.1 1.0 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.6 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.6 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.3 GO:1901383 negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.1 0.3 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.7 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 1.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.3 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 1.4 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.4 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.2 GO:1900369 transcription, RNA-templated(GO:0001172) negative regulation of RNA interference(GO:1900369)
0.1 0.3 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.1 0.4 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.4 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 1.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.5 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.3 GO:0003335 corneocyte development(GO:0003335)
0.1 1.4 GO:0006527 arginine catabolic process(GO:0006527)
0.1 3.0 GO:0030261 chromosome condensation(GO:0030261)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.2 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 2.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.8 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.2 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.4 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 2.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.4 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.1 1.0 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 1.3 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 0.6 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.7 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.1 0.4 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.8 GO:0070673 response to interleukin-18(GO:0070673)
0.1 0.9 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 0.4 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.7 GO:0061469 response to corticotropin-releasing hormone(GO:0043435) regulation of type B pancreatic cell proliferation(GO:0061469) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 1.5 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 1.1 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 1.3 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 1.0 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.2 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 7.4 GO:0031424 keratinization(GO:0031424)
0.0 0.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 1.0 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.5 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.4 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0045632 auditory receptor cell fate determination(GO:0042668) negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.8 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 1.7 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.2 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.0 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.6 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 1.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.4 GO:0001657 ureteric bud development(GO:0001657)
0.0 0.6 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0046598 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) positive regulation of viral entry into host cell(GO:0046598)
0.0 0.9 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0051592 response to calcium ion(GO:0051592)
0.0 0.9 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 1.8 GO:0048706 embryonic skeletal system development(GO:0048706)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.8 2.4 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.3 3.5 GO:0061689 tricellular tight junction(GO:0061689)
0.3 1.1 GO:0005607 laminin-2 complex(GO:0005607)
0.2 2.1 GO:0071953 elastic fiber(GO:0071953)
0.2 0.6 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 0.5 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 1.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 3.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 1.0 GO:0035976 AP1 complex(GO:0035976)
0.1 9.8 GO:0045095 keratin filament(GO:0045095)
0.1 2.3 GO:0005861 troponin complex(GO:0005861)
0.1 3.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.9 GO:0097486 alveolar lamellar body(GO:0097208) multivesicular body lumen(GO:0097486)
0.1 0.2 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.1 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.5 GO:1990393 3M complex(GO:1990393)
0.1 0.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 1.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 2.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 2.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.5 GO:0097443 sorting endosome(GO:0097443)
0.0 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.9 GO:0032433 filopodium tip(GO:0032433)
0.0 3.0 GO:0000786 nucleosome(GO:0000786)
0.0 1.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.6 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 1.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 6.7 GO:0001650 fibrillar center(GO:0001650)
0.0 1.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.4 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 2.0 GO:0005902 microvillus(GO:0005902)
0.0 2.3 GO:0044853 plasma membrane raft(GO:0044853)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.6 GO:0005581 collagen trimer(GO:0005581)
0.0 2.0 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 4.0 GO:0030017 sarcomere(GO:0030017)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 2.0 GO:0070160 occluding junction(GO:0070160)
0.0 0.5 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.3 1.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3 0.9 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 2.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 1.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 1.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 0.7 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 1.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 1.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.4 GO:0032810 sterol response element binding(GO:0032810)
0.1 1.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.7 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 3.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.2 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.5 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 3.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 2.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.6 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 4.1 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0038100 nodal binding(GO:0038100)
0.1 0.3 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 1.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.2 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 1.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.6 GO:0034711 inhibin binding(GO:0034711)
0.1 1.8 GO:0019841 retinol binding(GO:0019841)
0.1 0.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 1.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 5.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 3.9 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.6 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 4.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.6 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.6 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 6.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.7 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 3.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 8.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 3.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 2.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 2.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 8.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 4.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 2.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.9 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA