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Illumina Body Map 2, young vs old

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Results for FOSB

Z-value: 0.08

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Transcription factors associated with FOSB

Gene Symbol Gene ID Gene Info
FOSB
ENSG00000125740.9 FosB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSBhg19_v2_chr19_+_45971246_45971265-0.309.8e-02Click!

Activity profile of FOSB motif

Sorted Z-values of FOSB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_35685113 1.97 ENST00000419330.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr11_-_10920714 1.88 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr17_+_4853442 1.88 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr2_-_220173685 1.84 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr2_+_27505260 1.65 ENST00000380075.2
ENST00000296098.4
TRIM54
tripartite motif containing 54
chr17_-_8021710 1.57 ENST00000380149.1
ENST00000448843.2
ALOXE3
arachidonate lipoxygenase 3
chr1_-_190443931 1.57 ENST00000445957.2
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr14_-_75083313 1.55 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
CTD-2207P18.2
chr10_-_76818272 1.54 ENST00000338487.5
DUPD1
dual specificity phosphatase and pro isomerase domain containing 1
chr11_-_64527425 1.52 ENST00000377432.3
PYGM
phosphorylase, glycogen, muscle
chr5_-_176923803 1.51 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr6_-_24877490 1.49 ENST00000540914.1
ENST00000378023.4
FAM65B
family with sequence similarity 65, member B
chr2_-_97509749 1.46 ENST00000331001.2
ENST00000318357.4
ANKRD23
ankyrin repeat domain 23
chr11_-_10920838 1.43 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr11_+_10477733 1.43 ENST00000528723.1
AMPD3
adenosine monophosphate deaminase 3
chr2_-_97509729 1.40 ENST00000418232.1
ANKRD23
ankyrin repeat domain 23
chr6_-_113953705 1.36 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr10_-_75423560 1.36 ENST00000606523.1
SYNPO2L
synaptopodin 2-like
chr17_-_33390667 1.32 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr5_-_176923846 1.32 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr1_-_21059029 1.28 ENST00000444387.2
ENST00000375031.1
ENST00000518294.1
SH2D5
SH2 domain containing 5
chr18_+_74207477 1.19 ENST00000532511.1
RP11-17M16.1
uncharacterized protein LOC400658
chr21_+_30672433 1.16 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr1_+_223889285 1.13 ENST00000433674.2
CAPN2
calpain 2, (m/II) large subunit
chr5_+_175288631 1.13 ENST00000509837.1
CPLX2
complexin 2
chr19_-_35981358 1.12 ENST00000484218.2
ENST00000338897.3
KRTDAP
keratinocyte differentiation-associated protein
chr11_-_102714534 1.11 ENST00000299855.5
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr17_-_59668550 1.09 ENST00000521764.1
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr17_-_27503770 1.09 ENST00000533112.1
MYO18A
myosin XVIIIA
chr11_-_66103867 1.09 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr17_-_3595042 1.07 ENST00000552723.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr16_-_72206034 1.05 ENST00000537465.1
ENST00000237353.10
PMFBP1
polyamine modulated factor 1 binding protein 1
chr3_+_184534994 1.03 ENST00000441141.1
ENST00000445089.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr10_+_48247669 1.01 ENST00000457620.1
FAM25G
family with sequence similarity 25, member G
chr11_-_71781096 1.01 ENST00000535087.1
ENST00000535838.1
NUMA1
nuclear mitotic apparatus protein 1
chr10_-_47181681 1.00 ENST00000452267.1
FAM25B
family with sequence similarity 25, member B
chr1_+_22333943 1.00 ENST00000400271.2
CELA3A
chymotrypsin-like elastase family, member 3A
chr22_+_21369316 0.99 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
chr11_-_66103932 0.98 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr12_-_95010147 0.98 ENST00000548918.1
TMCC3
transmembrane and coiled-coil domain family 3
chr6_-_41673552 0.98 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr6_+_292051 0.97 ENST00000344450.5
DUSP22
dual specificity phosphatase 22
chr18_-_74207146 0.96 ENST00000443185.2
ZNF516
zinc finger protein 516
chr3_+_183894566 0.95 ENST00000439647.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr17_+_79650962 0.95 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr17_-_73150629 0.95 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
HN1
hematological and neurological expressed 1
chr4_+_84457529 0.95 ENST00000264409.4
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr16_+_30675654 0.95 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr18_+_9885760 0.95 ENST00000536353.2
ENST00000584255.1
TXNDC2
thioredoxin domain containing 2 (spermatozoa)
chr4_+_71588372 0.94 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr4_-_80329356 0.93 ENST00000358842.3
GK2
glycerol kinase 2
chr16_+_56782118 0.92 ENST00000566678.1
NUP93
nucleoporin 93kDa
chr17_+_80317121 0.91 ENST00000333437.4
TEX19
testis expressed 19
chr17_-_27467418 0.91 ENST00000528564.1
MYO18A
myosin XVIIIA
chr18_+_9885961 0.90 ENST00000306084.6
TXNDC2
thioredoxin domain containing 2 (spermatozoa)
chr12_-_95009837 0.88 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr4_+_41983713 0.88 ENST00000333141.5
DCAF4L1
DDB1 and CUL4 associated factor 4-like 1
chr3_-_196065374 0.87 ENST00000454715.1
TM4SF19
transmembrane 4 L six family member 19
chr11_-_65150103 0.87 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
SLC25A45
solute carrier family 25, member 45
chr4_+_84457250 0.86 ENST00000395226.2
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr16_+_56781814 0.86 ENST00000568656.1
NUP93
nucleoporin 93kDa
chr20_-_634000 0.85 ENST00000381962.3
SRXN1
sulfiredoxin 1
chr20_+_21686290 0.84 ENST00000398485.2
PAX1
paired box 1
chr4_+_170581213 0.84 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr11_-_46848393 0.84 ENST00000526496.1
CKAP5
cytoskeleton associated protein 5
chr12_-_96389702 0.83 ENST00000552509.1
HAL
histidine ammonia-lyase
chr6_-_35888905 0.81 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1
SRSF protein kinase 1
chr6_+_155537771 0.80 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr6_+_155538093 0.79 ENST00000462408.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr11_+_63448918 0.79 ENST00000341307.2
ENST00000356000.3
ENST00000542238.1
RTN3
reticulon 3
chr11_-_9781068 0.78 ENST00000500698.1
RP11-540A21.2
RP11-540A21.2
chr17_+_25799008 0.77 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr6_-_127837739 0.77 ENST00000368268.2
SOGA3
SOGA family member 3
chr19_-_18995029 0.75 ENST00000596048.1
CERS1
ceramide synthase 1
chr8_-_42623747 0.74 ENST00000534622.1
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr1_-_160231451 0.74 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr1_-_235116495 0.73 ENST00000549744.1
RP11-443B7.3
RP11-443B7.3
chr3_+_183894737 0.73 ENST00000432591.1
ENST00000431779.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr17_-_18908040 0.72 ENST00000388995.6
FAM83G
family with sequence similarity 83, member G
chr22_-_39151434 0.72 ENST00000439339.1
SUN2
Sad1 and UNC84 domain containing 2
chr10_+_88780049 0.71 ENST00000343959.4
FAM25A
family with sequence similarity 25, member A
chr9_-_35112376 0.71 ENST00000488109.2
FAM214B
family with sequence similarity 214, member B
chr18_+_9885934 0.70 ENST00000357775.5
TXNDC2
thioredoxin domain containing 2 (spermatozoa)
chr11_-_123756334 0.70 ENST00000528595.1
ENST00000375026.2
TMEM225
transmembrane protein 225
chr17_+_21191341 0.70 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr10_+_134901388 0.69 ENST00000392607.3
GPR123
G protein-coupled receptor 123
chr13_-_41768654 0.69 ENST00000379483.3
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr17_-_18161870 0.68 ENST00000579294.1
ENST00000545457.2
ENST00000379450.4
ENST00000578558.1
FLII
flightless I homolog (Drosophila)
chr15_+_67458357 0.67 ENST00000537194.2
SMAD3
SMAD family member 3
chr19_-_36019123 0.67 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN
suprabasin
chr1_-_179112189 0.67 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr2_+_208104497 0.66 ENST00000430494.1
AC007879.7
AC007879.7
chr7_+_142919130 0.66 ENST00000408947.3
TAS2R40
taste receptor, type 2, member 40
chr15_+_67418047 0.66 ENST00000540846.2
SMAD3
SMAD family member 3
chr10_-_111713633 0.66 ENST00000538668.1
ENST00000369657.1
ENST00000369655.1
RP11-451M19.3
Uncharacterized protein
chr14_-_96180435 0.66 ENST00000556450.1
ENST00000555202.1
ENST00000554012.1
ENST00000402399.1
TCL1A
T-cell leukemia/lymphoma 1A
chr5_+_145317356 0.65 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr6_+_108487245 0.65 ENST00000368986.4
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr5_+_143191726 0.64 ENST00000289448.2
HMHB1
histocompatibility (minor) HB-1
chr1_+_101003687 0.64 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr19_+_38880695 0.64 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chrX_-_154493791 0.64 ENST00000369454.3
RAB39B
RAB39B, member RAS oncogene family
chr9_-_114246635 0.63 ENST00000338205.5
KIAA0368
KIAA0368
chr12_-_96390063 0.63 ENST00000541929.1
HAL
histidine ammonia-lyase
chr16_+_89988259 0.63 ENST00000554444.1
ENST00000556565.1
TUBB3
Tubulin beta-3 chain
chr3_-_18466787 0.63 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr9_+_137218362 0.62 ENST00000481739.1
RXRA
retinoid X receptor, alpha
chr6_+_159290917 0.62 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr18_-_40695604 0.62 ENST00000590910.1
ENST00000326695.5
ENST00000589109.1
ENST00000282028.4
RIT2
Ras-like without CAAX 2
chr12_-_45315625 0.62 ENST00000552993.1
NELL2
NEL-like 2 (chicken)
chr8_-_125384927 0.61 ENST00000297632.6
TMEM65
transmembrane protein 65
chr17_+_30771279 0.60 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr8_+_123875624 0.60 ENST00000534247.1
ZHX2
zinc fingers and homeoboxes 2
chr2_-_119605253 0.59 ENST00000295206.6
EN1
engrailed homeobox 1
chr8_-_17752996 0.58 ENST00000381841.2
ENST00000427924.1
FGL1
fibrinogen-like 1
chr11_-_94965667 0.58 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr16_-_4664860 0.58 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1
UBA-like domain containing 1
chr9_+_97562440 0.57 ENST00000395357.2
C9orf3
chromosome 9 open reading frame 3
chr12_+_6644443 0.57 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr17_+_35851570 0.57 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr17_-_72864739 0.56 ENST00000579893.1
ENST00000544854.1
FDXR
ferredoxin reductase
chr8_-_110988070 0.55 ENST00000524391.1
KCNV1
potassium channel, subfamily V, member 1
chr17_+_75315534 0.55 ENST00000590294.1
ENST00000329047.8
SEPT9
septin 9
chr9_+_34992846 0.55 ENST00000443266.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr16_-_80603558 0.55 ENST00000567317.1
RP11-18F14.1
RP11-18F14.1
chr5_-_61031495 0.54 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
CTD-2170G1.2
chr14_-_74226961 0.54 ENST00000286523.5
ENST00000435371.1
ELMSAN1
ELM2 and Myb/SANT-like domain containing 1
chr12_+_53693466 0.54 ENST00000267103.5
ENST00000548632.1
C12orf10
chromosome 12 open reading frame 10
chr19_+_926000 0.53 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr17_+_75446819 0.53 ENST00000541152.2
ENST00000591704.1
SEPT9
septin 9
chr17_-_28257080 0.52 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2
slingshot protein phosphatase 2
chr12_+_52695617 0.52 ENST00000293525.5
KRT86
keratin 86
chr1_-_93257951 0.51 ENST00000543509.1
ENST00000370331.1
ENST00000540033.1
EVI5
ecotropic viral integration site 5
chr3_+_48507210 0.51 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr6_-_35888824 0.51 ENST00000361690.3
ENST00000512445.1
SRPK1
SRSF protein kinase 1
chr12_-_96390108 0.51 ENST00000538703.1
ENST00000261208.3
HAL
histidine ammonia-lyase
chr1_-_6662919 0.51 ENST00000377658.4
ENST00000377663.3
KLHL21
kelch-like family member 21
chr7_-_142120321 0.50 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr3_+_113465866 0.50 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr10_+_121410882 0.50 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr13_-_52027134 0.50 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr3_+_48507621 0.50 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr3_-_18466026 0.50 ENST00000417717.2
SATB1
SATB homeobox 1
chr2_-_219858123 0.49 ENST00000453769.1
ENST00000295728.2
ENST00000392096.2
CRYBA2
crystallin, beta A2
chrX_+_133371077 0.49 ENST00000517294.1
ENST00000370809.4
CCDC160
coiled-coil domain containing 160
chr12_+_58176525 0.49 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr3_+_108308845 0.49 ENST00000479138.1
DZIP3
DAZ interacting zinc finger protein 3
chr17_-_27405875 0.49 ENST00000359450.6
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr15_+_75335604 0.48 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr4_+_120056939 0.48 ENST00000307128.5
MYOZ2
myozenin 2
chr2_-_145275109 0.48 ENST00000431672.2
ZEB2
zinc finger E-box binding homeobox 2
chr7_+_33765593 0.48 ENST00000311067.3
RP11-89N17.1
HCG1643653; Uncharacterized protein
chr22_-_32860427 0.48 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPIFC
BPI fold containing family C
chr10_-_29923893 0.47 ENST00000355867.4
SVIL
supervillin
chr17_-_38911580 0.47 ENST00000312150.4
KRT25
keratin 25
chr12_+_28605426 0.46 ENST00000542801.1
CCDC91
coiled-coil domain containing 91
chr15_+_45938079 0.46 ENST00000561493.1
SQRDL
sulfide quinone reductase-like (yeast)
chr5_-_41794663 0.46 ENST00000510634.1
OXCT1
3-oxoacid CoA transferase 1
chr16_-_4665023 0.46 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr1_-_207224307 0.46 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr11_-_65430251 0.46 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr2_+_27237615 0.45 ENST00000458529.1
ENST00000402218.1
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr1_-_236046872 0.45 ENST00000536965.1
LYST
lysosomal trafficking regulator
chr17_-_7123021 0.45 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr3_-_51994694 0.44 ENST00000395014.2
PCBP4
poly(rC) binding protein 4
chr2_-_96926313 0.44 ENST00000435268.1
TMEM127
transmembrane protein 127
chr21_+_19617140 0.44 ENST00000299295.2
ENST00000338326.3
CHODL
chondrolectin
chr11_-_124180733 0.44 ENST00000357821.2
OR8D1
olfactory receptor, family 8, subfamily D, member 1
chr17_+_76311791 0.43 ENST00000586321.1
AC061992.2
AC061992.2
chr12_+_7023491 0.43 ENST00000541477.1
ENST00000229277.1
ENO2
enolase 2 (gamma, neuronal)
chr19_-_46145696 0.43 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chr3_-_131756559 0.42 ENST00000505957.1
CPNE4
copine IV
chr8_-_42623924 0.42 ENST00000276410.2
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr1_+_154975258 0.42 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr9_+_131902346 0.42 ENST00000432124.1
ENST00000435305.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr8_-_17752912 0.42 ENST00000398054.1
ENST00000381840.2
FGL1
fibrinogen-like 1
chr14_+_31494672 0.41 ENST00000542754.2
ENST00000313566.6
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr11_-_75201791 0.40 ENST00000529721.1
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr12_-_118628350 0.40 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr10_+_68685764 0.40 ENST00000361320.4
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr7_-_102985035 0.40 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr19_-_55881741 0.39 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11
interleukin 11
chr16_-_67281413 0.39 ENST00000258201.4
FHOD1
formin homology 2 domain containing 1
chr5_+_159436120 0.38 ENST00000522793.1
ENST00000231238.5
TTC1
tetratricopeptide repeat domain 1
chr16_-_1429627 0.38 ENST00000248104.7
UNKL
unkempt family zinc finger-like
chr20_+_48429356 0.38 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr3_+_157828152 0.38 ENST00000476899.1
RSRC1
arginine/serine-rich coiled-coil 1
chr6_+_2988847 0.37 ENST00000380472.3
ENST00000605901.1
ENST00000454015.1
NQO2
LINC01011
NAD(P)H dehydrogenase, quinone 2
long intergenic non-protein coding RNA 1011
chr11_+_68671310 0.37 ENST00000255078.3
ENST00000539224.1
IGHMBP2
immunoglobulin mu binding protein 2
chr14_+_97925151 0.37 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1
CTD-2506J14.1
chr5_-_41794313 0.37 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr6_-_35888858 0.37 ENST00000507909.1
SRPK1
SRSF protein kinase 1
chr1_+_17634689 0.36 ENST00000375453.1
ENST00000375448.4
PADI4
peptidyl arginine deiminase, type IV
chr11_-_47206965 0.36 ENST00000525725.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr10_-_86001210 0.36 ENST00000372105.3
LRIT1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr1_+_110026544 0.36 ENST00000369870.3
ATXN7L2
ataxin 7-like 2
chr12_+_55968199 0.36 ENST00000321688.1
OR2AP1
olfactory receptor, family 2, subfamily AP, member 1
chr20_+_48429233 0.36 ENST00000417961.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr1_-_153029980 0.36 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr16_-_1429674 0.36 ENST00000403703.1
ENST00000397464.1
ENST00000402641.2
UNKL
unkempt family zinc finger-like

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:1903028 positive regulation of opsonization(GO:1903028)
0.5 1.8 GO:1990502 dense core granule maturation(GO:1990502)
0.3 0.9 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.3 1.2 GO:0061743 motor learning(GO:0061743)
0.3 2.0 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.2 0.7 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.2 1.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 1.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 0.6 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.2 2.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.4 GO:0006196 AMP catabolic process(GO:0006196)
0.2 1.8 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.2 1.6 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 1.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 0.7 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 0.6 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 0.5 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.2 0.5 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.2 0.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 2.5 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.1 0.8 GO:0061056 sclerotome development(GO:0061056)
0.1 0.8 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 2.9 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.1 0.4 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.5 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.1 0.3 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.9 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 1.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.8 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.6 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 1.0 GO:1902365 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 1.7 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.4 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 1.1 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.4 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.8 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 2.2 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.1 1.0 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.3 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.3 GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.1 0.7 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 1.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.1 1.4 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.4 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.5 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.6 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.1 0.2 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.0 0.4 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 1.2 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 3.0 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.5 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 1.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 2.1 GO:0033198 response to ATP(GO:0033198)
0.0 0.2 GO:0044805 late nucleophagy(GO:0044805)
0.0 1.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097)
0.0 0.7 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.0 0.5 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:2000321 interleukin-18 production(GO:0032621) positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 1.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.7 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.3 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 1.0 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.4 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.2 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.1 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.4 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 1.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0032899 regulation of neurotrophin production(GO:0032899) negative regulation of neurotrophin production(GO:0032900)
0.0 0.4 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 1.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.6 GO:0051014 actin filament severing(GO:0051014)
0.0 0.5 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.5 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.5 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0048631 negative regulation of skeletal muscle cell proliferation(GO:0014859) skeletal muscle tissue growth(GO:0048630) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.0 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.5 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 1.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.4 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 2.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.7 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 1.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.2 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 1.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.5 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 1.2 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.5 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.3 2.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.6 GO:0097447 dendritic tree(GO:0097447)
0.2 1.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.2 2.5 GO:0001520 outer dense fiber(GO:0001520)
0.2 1.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 0.5 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 1.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 3.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.0 GO:0033263 CORVET complex(GO:0033263)
0.1 1.0 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.3 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.7 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 1.9 GO:0036020 endolysosome membrane(GO:0036020)
0.1 0.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.3 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.4 GO:0031415 NatA complex(GO:0031415)
0.1 1.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.5 GO:0005827 polar microtubule(GO:0005827)
0.0 0.5 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.4 GO:0031105 septin complex(GO:0031105)
0.0 1.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.0 5.4 GO:0042641 actomyosin(GO:0042641)
0.0 0.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 1.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 3.2 GO:0014704 intercalated disc(GO:0014704)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290) Flemming body(GO:0090543)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 2.5 GO:0030175 filopodium(GO:0030175)
0.0 1.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.7 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.4 1.5 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.3 1.6 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.3 0.9 GO:0004370 glycerol kinase activity(GO:0004370)
0.3 2.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.8 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 1.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 0.6 GO:0015039 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.2 2.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 2.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 1.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 0.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.6 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.9 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.5 GO:0051373 FATZ binding(GO:0051373)
0.1 0.5 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.4 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 2.9 GO:0031432 titin binding(GO:0031432)
0.1 0.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.3 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.1 0.2 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.4 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.1 0.3 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 1.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.2 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 1.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 3.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 1.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 1.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 2.0 GO:0043531 ADP binding(GO:0043531)
0.0 0.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.4 GO:0004860 protein kinase inhibitor activity(GO:0004860) protein kinase regulator activity(GO:0019887)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 0.3 GO:0070402 NADPH binding(GO:0070402)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID ARF 3PATHWAY Arf1 pathway
0.0 2.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.2 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 1.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.8 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.8 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis