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Illumina Body Map 2, young vs old

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Results for FOXF2_FOXJ1

Z-value: 0.02

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Transcription factors associated with FOXF2_FOXJ1

Gene Symbol Gene ID Gene Info
FOXF2
ENSG00000137273.3 forkhead box F2
FOXJ1
ENSG00000129654.7 forkhead box J1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXF2hg19_v2_chr6_+_1389989_13900690.106.0e-01Click!
FOXJ1hg19_v2_chr17_-_74137374_74137385-0.096.3e-01Click!

Activity profile of FOXF2_FOXJ1 motif

Sorted Z-values of FOXF2_FOXJ1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_72426891 4.67 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr12_-_71551652 4.18 ENST00000546561.1
TSPAN8
tetraspanin 8
chr11_-_119247004 3.36 ENST00000531070.1
USP2
ubiquitin specific peptidase 2
chr17_+_72427477 3.17 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr6_-_56707943 3.02 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST
dystonin
chr5_-_42811986 2.68 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr10_-_13570533 2.58 ENST00000396900.2
ENST00000396898.2
BEND7
BEN domain containing 7
chr16_+_6069586 2.57 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr20_+_33563206 2.55 ENST00000262873.7
MYH7B
myosin, heavy chain 7B, cardiac muscle, beta
chr16_+_6069072 2.49 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr8_+_67344710 2.47 ENST00000379385.4
ENST00000396623.3
ENST00000415254.1
ADHFE1
alcohol dehydrogenase, iron containing, 1
chr7_+_123241908 2.42 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15
ankyrin repeat and SOCS box containing 15
chr4_+_100495864 2.37 ENST00000265517.5
ENST00000422897.2
MTTP
microsomal triglyceride transfer protein
chr2_-_172750733 2.26 ENST00000392592.4
ENST00000422440.2
SLC25A12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr5_-_36301984 2.23 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr3_-_10547192 2.15 ENST00000360273.2
ENST00000343816.4
ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr4_-_186456652 2.14 ENST00000284767.5
ENST00000284770.5
PDLIM3
PDZ and LIM domain 3
chr5_-_142065612 2.13 ENST00000360966.5
ENST00000411960.1
FGF1
fibroblast growth factor 1 (acidic)
chr5_-_42812143 2.12 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr1_+_185703513 2.08 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr1_-_57431679 2.07 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
C8B
complement component 8, beta polypeptide
chr11_+_113930955 2.01 ENST00000535700.1
ZBTB16
zinc finger and BTB domain containing 16
chr20_+_44035200 2.01 ENST00000372717.1
ENST00000360981.4
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr1_+_81771806 1.96 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr4_-_186456766 1.93 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr3_+_50712672 1.93 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr14_+_32964258 1.83 ENST00000556638.1
AKAP6
A kinase (PRKA) anchor protein 6
chr19_+_7580103 1.79 ENST00000596712.1
ZNF358
zinc finger protein 358
chr3_-_10547333 1.73 ENST00000383800.4
ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr2_-_233877912 1.64 ENST00000264051.3
NGEF
neuronal guanine nucleotide exchange factor
chr5_+_140579162 1.58 ENST00000536699.1
ENST00000354757.3
PCDHB11
protocadherin beta 11
chr12_-_71551868 1.46 ENST00000247829.3
TSPAN8
tetraspanin 8
chr4_-_152149033 1.43 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr14_-_21493649 1.43 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2
NDRG family member 2
chr12_-_15374343 1.40 ENST00000256953.2
ENST00000546331.1
RERG
RAS-like, estrogen-regulated, growth inhibitor
chr2_-_179567206 1.38 ENST00000414766.1
TTN
titin
chr10_-_118032697 1.35 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr10_-_375422 1.35 ENST00000434695.2
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr2_+_233527443 1.33 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr1_+_214161854 1.30 ENST00000435016.1
PROX1
prospero homeobox 1
chr13_-_39564993 1.29 ENST00000423210.1
STOML3
stomatin (EPB72)-like 3
chr11_-_8739383 1.29 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chr3_+_159570722 1.21 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr18_-_56296182 1.20 ENST00000361673.3
ALPK2
alpha-kinase 2
chr19_+_18496957 1.18 ENST00000252809.3
GDF15
growth differentiation factor 15
chr17_+_33474826 1.14 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B
unc-45 homolog B (C. elegans)
chr18_-_25739260 1.12 ENST00000413878.1
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr17_+_33474860 1.10 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chr5_-_59064458 1.09 ENST00000502575.1
ENST00000507116.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr10_-_4285835 1.08 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr3_-_185826855 1.08 ENST00000306376.5
ETV5
ets variant 5
chr18_-_52626622 1.07 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chr6_-_76203454 1.05 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr13_-_103053946 1.05 ENST00000376131.4
FGF14
fibroblast growth factor 14
chr8_+_120079478 1.04 ENST00000332843.2
COLEC10
collectin sub-family member 10 (C-type lectin)
chr4_-_186682716 1.04 ENST00000445343.1
SORBS2
sorbin and SH3 domain containing 2
chr5_+_150040403 1.02 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr15_+_42697065 1.02 ENST00000565559.1
CAPN3
calpain 3, (p94)
chr9_+_136287444 1.01 ENST00000355699.2
ENST00000356589.2
ENST00000371911.3
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr18_-_25616519 0.99 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr19_-_36523709 0.98 ENST00000592017.1
ENST00000360535.4
CLIP3
CAP-GLY domain containing linker protein 3
chr8_-_124553437 0.97 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr1_+_66796401 0.95 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr14_-_74551172 0.94 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr20_+_44035847 0.93 ENST00000372712.2
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr1_-_246729544 0.93 ENST00000544618.1
ENST00000366514.4
TFB2M
transcription factor B2, mitochondrial
chr14_-_74551096 0.92 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr15_+_42697018 0.92 ENST00000397204.4
CAPN3
calpain 3, (p94)
chr1_+_246729724 0.92 ENST00000366513.4
ENST00000366512.3
CNST
consortin, connexin sorting protein
chr11_-_63933504 0.91 ENST00000255681.6
MACROD1
MACRO domain containing 1
chr6_-_76203345 0.90 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr8_-_70747205 0.90 ENST00000260126.4
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr10_-_4285923 0.89 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr13_-_61989655 0.88 ENST00000409204.4
PCDH20
protocadherin 20
chr11_-_8739566 0.88 ENST00000533020.1
ST5
suppression of tumorigenicity 5
chr12_+_94071129 0.87 ENST00000552983.1
ENST00000332896.3
ENST00000552033.1
ENST00000548483.1
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr14_-_104408032 0.87 ENST00000455348.2
RD3L
retinal degeneration 3-like
chr19_-_47157914 0.84 ENST00000300875.4
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr21_+_17442799 0.84 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_-_21928515 0.84 ENST00000537950.1
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr19_-_18902106 0.83 ENST00000542601.2
ENST00000425807.1
ENST00000222271.2
COMP
cartilage oligomeric matrix protein
chr15_+_63188009 0.83 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr2_-_37193606 0.82 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr1_-_47131521 0.82 ENST00000542495.1
ENST00000532925.1
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr6_+_101846664 0.81 ENST00000421544.1
ENST00000413795.1
ENST00000369138.1
ENST00000358361.3
GRIK2
glutamate receptor, ionotropic, kainate 2
chr14_+_56127960 0.81 ENST00000553624.1
KTN1
kinectin 1 (kinesin receptor)
chr10_-_118032979 0.81 ENST00000355422.6
GFRA1
GDNF family receptor alpha 1
chr10_+_52751010 0.80 ENST00000373985.1
PRKG1
protein kinase, cGMP-dependent, type I
chr9_+_113431059 0.80 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase
chr10_+_111985837 0.79 ENST00000393134.1
MXI1
MAX interactor 1, dimerization protein
chr9_+_131903916 0.78 ENST00000419582.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr1_+_246729815 0.78 ENST00000366511.1
CNST
consortin, connexin sorting protein
chr5_+_140529630 0.78 ENST00000543635.1
PCDHB6
protocadherin beta 6
chr20_-_52645231 0.78 ENST00000448484.1
BCAS1
breast carcinoma amplified sequence 1
chr5_+_140734570 0.77 ENST00000571252.1
PCDHGA4
protocadherin gamma subfamily A, 4
chr3_-_164914640 0.77 ENST00000241274.3
SLITRK3
SLIT and NTRK-like family, member 3
chr2_+_103236004 0.77 ENST00000233969.2
SLC9A2
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr10_+_75668916 0.76 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr16_-_86542652 0.74 ENST00000599749.1
FENDRR
FOXF1 adjacent non-coding developmental regulatory RNA
chr17_-_8059638 0.74 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1
period circadian clock 1
chrX_+_85969626 0.73 ENST00000484479.1
DACH2
dachshund homolog 2 (Drosophila)
chr3_-_58523010 0.73 ENST00000459701.2
ENST00000302819.5
ACOX2
acyl-CoA oxidase 2, branched chain
chr9_+_131904233 0.73 ENST00000432651.1
ENST00000435132.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr4_-_140223614 0.73 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr2_-_180610767 0.71 ENST00000409343.1
ZNF385B
zinc finger protein 385B
chr2_+_179184955 0.70 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr12_-_15038779 0.68 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr6_-_112575687 0.68 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4
laminin, alpha 4
chr2_+_33661382 0.68 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_+_200011711 0.67 ENST00000544748.1
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr12_+_111284764 0.67 ENST00000545036.1
ENST00000308208.5
CCDC63
coiled-coil domain containing 63
chr6_-_112575912 0.67 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr14_+_50234827 0.66 ENST00000554589.1
ENST00000557247.1
KLHDC2
kelch domain containing 2
chr4_+_15376165 0.65 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr12_-_15374328 0.64 ENST00000537647.1
RERG
RAS-like, estrogen-regulated, growth inhibitor
chr9_-_86432547 0.64 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr6_+_101847105 0.64 ENST00000369137.3
ENST00000318991.6
GRIK2
glutamate receptor, ionotropic, kainate 2
chr11_-_27723158 0.64 ENST00000395980.2
BDNF
brain-derived neurotrophic factor
chr1_+_47533160 0.63 ENST00000334194.3
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr12_-_53343560 0.62 ENST00000548998.1
KRT8
keratin 8
chr19_-_36523529 0.62 ENST00000593074.1
CLIP3
CAP-GLY domain containing linker protein 3
chrX_-_38080077 0.62 ENST00000378533.3
ENST00000544439.1
ENST00000432886.2
ENST00000538295.1
SRPX
sushi-repeat containing protein, X-linked
chr11_+_67374323 0.62 ENST00000322776.6
ENST00000532303.1
ENST00000532244.1
ENST00000528328.1
ENST00000529927.1
ENST00000532343.1
ENST00000415352.2
ENST00000533075.1
ENST00000529867.1
ENST00000530638.1
NDUFV1
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
chr7_-_140340576 0.61 ENST00000275884.6
ENST00000475837.1
DENND2A
DENN/MADD domain containing 2A
chr2_+_162272605 0.61 ENST00000389554.3
TBR1
T-box, brain, 1
chr14_-_61191049 0.60 ENST00000556952.3
SIX4
SIX homeobox 4
chr22_-_37505588 0.60 ENST00000406856.1
TMPRSS6
transmembrane protease, serine 6
chr20_+_31823792 0.60 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPIFA1
BPI fold containing family A, member 1
chr9_-_136451319 0.59 ENST00000496132.1
FAM163B
family with sequence similarity 163, member B
chr6_-_56716686 0.59 ENST00000520645.1
DST
dystonin
chr1_+_65730385 0.59 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr6_+_146348782 0.58 ENST00000361719.2
ENST00000392299.2
GRM1
glutamate receptor, metabotropic 1
chr10_+_111985713 0.58 ENST00000239007.7
MXI1
MAX interactor 1, dimerization protein
chr3_+_132316081 0.58 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr12_+_111284805 0.57 ENST00000552694.1
CCDC63
coiled-coil domain containing 63
chr5_+_140797296 0.57 ENST00000398594.2
PCDHGB7
protocadherin gamma subfamily B, 7
chr9_+_131904295 0.56 ENST00000434095.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr12_-_53343633 0.56 ENST00000546826.1
KRT8
keratin 8
chr17_-_8263538 0.56 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr11_-_16419067 0.56 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr17_-_19290483 0.56 ENST00000395592.2
ENST00000299610.4
MFAP4
microfibrillar-associated protein 4
chr18_+_28898052 0.55 ENST00000257192.4
DSG1
desmoglein 1
chr14_-_21493123 0.55 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
NDRG family member 2
chr11_-_85397167 0.54 ENST00000316398.3
CCDC89
coiled-coil domain containing 89
chr12_-_53343602 0.54 ENST00000546897.1
ENST00000552551.1
KRT8
keratin 8
chr2_-_39456673 0.53 ENST00000378803.1
ENST00000395035.3
CDKL4
cyclin-dependent kinase-like 4
chr6_+_146348810 0.53 ENST00000492807.2
GRM1
glutamate receptor, metabotropic 1
chr4_+_71587669 0.52 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr2_+_86947296 0.52 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr11_-_115375107 0.52 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr15_-_58571445 0.51 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr11_+_22688615 0.51 ENST00000533363.1
GAS2
growth arrest-specific 2
chr3_+_52245458 0.51 ENST00000459884.1
ALAS1
aminolevulinate, delta-, synthase 1
chr12_+_20963632 0.51 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr6_-_112575758 0.50 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4
laminin, alpha 4
chr7_+_12250943 0.50 ENST00000442107.1
TMEM106B
transmembrane protein 106B
chr20_-_62582475 0.50 ENST00000369908.5
UCKL1
uridine-cytidine kinase 1-like 1
chr4_+_172734548 0.50 ENST00000506823.1
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr4_+_71588372 0.50 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr8_+_79428539 0.50 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr1_+_15668240 0.49 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr4_+_88754113 0.49 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr6_+_72922505 0.48 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_168106536 0.48 ENST00000537209.1
ENST00000361697.2
ENST00000546300.1
ENST00000367835.1
GPR161
G protein-coupled receptor 161
chr4_+_88754069 0.48 ENST00000395102.4
ENST00000497649.2
MEPE
matrix extracellular phosphoglycoprotein
chr12_+_20963647 0.47 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr14_+_56127989 0.47 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr12_-_114843889 0.47 ENST00000405440.2
TBX5
T-box 5
chr4_-_140223670 0.45 ENST00000394228.1
ENST00000539387.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr5_+_65222500 0.45 ENST00000511297.1
ENST00000506030.1
ERBB2IP
erbb2 interacting protein
chr6_+_84563295 0.45 ENST00000369687.1
RIPPLY2
ripply transcriptional repressor 2
chr19_+_41725140 0.44 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr16_+_4666475 0.42 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr3_+_187461442 0.42 ENST00000450760.1
RP11-211G3.2
RP11-211G3.2
chr4_+_104346194 0.42 ENST00000510200.1
RP11-328K4.1
RP11-328K4.1
chr4_+_117220016 0.42 ENST00000604093.1
MTRNR2L13
MT-RNR2-like 13 (pseudogene)
chr22_-_37505449 0.42 ENST00000406725.1
TMPRSS6
transmembrane protease, serine 6
chr18_+_18943554 0.41 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chrX_+_9880412 0.41 ENST00000418909.2
SHROOM2
shroom family member 2
chr21_+_17443521 0.41 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_-_106480587 0.41 ENST00000548902.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr6_+_72922590 0.40 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1
chr19_+_41768561 0.40 ENST00000599719.1
ENST00000601309.1
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr1_-_149982624 0.40 ENST00000417191.1
ENST00000369135.4
OTUD7B
OTU domain containing 7B
chr17_+_67410832 0.39 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr12_-_21556577 0.39 ENST00000450590.1
ENST00000453443.1
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr16_-_65106110 0.38 ENST00000562882.1
ENST00000567934.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr8_+_35649365 0.38 ENST00000437887.1
AC012215.1
Uncharacterized protein
chr3_-_185826718 0.37 ENST00000413301.1
ENST00000421809.1
ETV5
ets variant 5
chr15_-_31283798 0.37 ENST00000435680.1
ENST00000425768.1
MTMR10
myotubularin related protein 10
chr18_-_74844727 0.37 ENST00000355994.2
ENST00000579129.1
MBP
myelin basic protein
chr15_-_31283618 0.37 ENST00000563714.1
MTMR10
myotubularin related protein 10
chr5_+_81601166 0.36 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr14_-_81916501 0.36 ENST00000555001.1
RP11-299L17.3
RP11-299L17.3
chr1_-_24469602 0.36 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr3_+_98451532 0.36 ENST00000486334.2
ENST00000394162.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr19_+_18492973 0.36 ENST00000595973.2
GDF15
growth differentiation factor 15
chr20_-_22566089 0.35 ENST00000377115.4
FOXA2
forkhead box A2
chr9_-_88896977 0.35 ENST00000311534.6
ISCA1
iron-sulfur cluster assembly 1
chr20_+_45338126 0.35 ENST00000359271.2
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXF2_FOXJ1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0015993 molecular hydrogen transport(GO:0015993)
0.6 2.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.5 1.9 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.4 1.3 GO:0061114 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.4 3.5 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 1.7 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.3 2.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.3 1.9 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.2 0.9 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 1.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 3.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 0.6 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.2 1.6 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.2 1.4 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.2 0.8 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 2.7 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.2 3.5 GO:0045475 locomotor rhythm(GO:0045475)
0.2 2.1 GO:2000809 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) positive regulation of synaptic vesicle clustering(GO:2000809)
0.2 0.8 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 0.8 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.2 0.6 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.2 0.5 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 0.6 GO:1900190 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1 2.4 GO:0034378 chylomicron assembly(GO:0034378)
0.1 2.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.8 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 1.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.4 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 2.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 1.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 0.7 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 1.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 2.0 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.6 GO:0021764 amygdala development(GO:0021764)
0.1 1.7 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 0.5 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.6 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.7 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.4 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.6 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.5 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.7 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.3 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 1.9 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.2 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 7.4 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.3 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 2.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.3 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.5 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 1.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.5 GO:0035799 ureter maturation(GO:0035799)
0.1 0.4 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 1.0 GO:0035864 response to potassium ion(GO:0035864)
0.1 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.5 GO:0044211 CTP salvage(GO:0044211)
0.1 0.4 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.3 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 5.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 1.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.9 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 2.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.8 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 2.1 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0051029 rRNA transport(GO:0051029)
0.0 0.4 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.8 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 1.8 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.4 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 1.4 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0072642 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) telomerase RNA stabilization(GO:0090669) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.7 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 3.8 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.4 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 1.0 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 1.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:1902527 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.4 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 2.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.8 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.0 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.9 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.7 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 1.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 1.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.6 GO:0099536 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916) synaptic signaling(GO:0099536) trans-synaptic signaling(GO:0099537)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 1.0 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.2 GO:0033572 transferrin transport(GO:0033572)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.6 GO:0031673 H zone(GO:0031673)
0.3 1.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.2 2.1 GO:0005579 membrane attack complex(GO:0005579)
0.2 0.5 GO:0034657 GID complex(GO:0034657)
0.1 2.5 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 2.3 GO:0005916 fascia adherens(GO:0005916) catenin complex(GO:0016342)
0.1 1.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 13.4 GO:0030018 Z disc(GO:0030018)
0.1 0.6 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0070701 mucus layer(GO:0070701)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0036457 keratohyalin granule(GO:0036457)
0.0 0.5 GO:0034464 BBSome(GO:0034464)
0.0 1.8 GO:0005605 basal lamina(GO:0005605)
0.0 1.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.6 GO:0005776 autophagosome(GO:0005776)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0033643 host cell part(GO:0033643)
0.0 8.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 3.1 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.8 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.9 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 3.3 GO:0030426 growth cone(GO:0030426)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 7.8 GO:0043235 receptor complex(GO:0043235)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.3 1.6 GO:0097001 ceramide binding(GO:0097001)
0.2 2.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 0.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.2 0.8 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.2 0.8 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.2 1.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 2.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 1.0 GO:0051373 FATZ binding(GO:0051373)
0.2 0.5 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.2 1.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.8 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 0.9 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.3 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.7 GO:0071253 connexin binding(GO:0071253)
0.1 1.4 GO:0031433 telethonin binding(GO:0031433)
0.1 0.8 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 3.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.7 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 2.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 2.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 2.1 GO:0044548 S100 protein binding(GO:0044548)
0.1 3.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.9 GO:0031432 titin binding(GO:0031432)
0.1 0.4 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 2.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.5 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 3.4 GO:0030332 cyclin binding(GO:0030332)
0.1 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.3 GO:1902444 riboflavin binding(GO:1902444)
0.0 1.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.0 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.9 GO:0070513 death domain binding(GO:0070513)
0.0 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 5.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 2.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.3 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 2.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.5 GO:0034452 dynactin binding(GO:0034452)
0.0 0.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 2.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 2.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0010181 FMN binding(GO:0010181)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.8 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 1.7 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0046965 glucocorticoid receptor binding(GO:0035259) retinoid X receptor binding(GO:0046965)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 3.1 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 5.1 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.6 GO:0019956 chemokine binding(GO:0019956)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 5.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 3.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 5.3 PID FGF PATHWAY FGF signaling pathway
0.0 2.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.9 PID FOXO PATHWAY FoxO family signaling
0.0 3.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 3.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 3.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 3.3 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 1.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 2.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 2.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 2.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 4.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation