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Illumina Body Map 2, young vs old

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Results for FOXN1

Z-value: 0.84

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Transcription factors associated with FOXN1

Gene Symbol Gene ID Gene Info
FOXN1
ENSG00000109101.3 forkhead box N1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXN1hg19_v2_chr17_+_26833250_26833278-0.086.5e-01Click!

Activity profile of FOXN1 motif

Sorted Z-values of FOXN1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_47308128 2.08 ENST00000413580.1
ENST00000511066.1
PHOSPHO1
phosphatase, orphan 1
chr5_+_110559603 2.07 ENST00000512453.1
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr17_-_42462688 1.95 ENST00000377068.3
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr3_-_38691119 1.65 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
SCN5A
sodium channel, voltage-gated, type V, alpha subunit
chr5_+_110559784 1.63 ENST00000282356.4
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr17_-_47308100 1.61 ENST00000503902.1
ENST00000512250.1
PHOSPHO1
phosphatase, orphan 1
chr5_-_79866054 1.61 ENST00000508916.1
ANKRD34B
ankyrin repeat domain 34B
chr1_+_181057638 1.56 ENST00000367577.4
IER5
immediate early response 5
chr14_-_51297360 1.55 ENST00000496749.1
NIN
ninein (GSK3B interacting protein)
chr2_+_46769798 1.53 ENST00000238738.4
RHOQ
ras homolog family member Q
chrX_-_21676442 1.49 ENST00000379499.2
KLHL34
kelch-like family member 34
chrY_+_22737678 1.45 ENST00000382772.3
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked
chr14_+_61788429 1.37 ENST00000332981.5
PRKCH
protein kinase C, eta
chr1_-_25256368 1.35 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr8_+_38243721 1.34 ENST00000527334.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr5_-_99870932 1.33 ENST00000504833.1
CTD-2001C12.1
CTD-2001C12.1
chrX_-_108868390 1.30 ENST00000372101.2
KCNE1L
KCNE1-like
chr14_-_92302825 1.29 ENST00000556018.1
TC2N
tandem C2 domains, nuclear
chr8_+_38243967 1.28 ENST00000524874.1
ENST00000379957.4
ENST00000523983.2
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr14_-_92302784 1.28 ENST00000340892.5
ENST00000360594.5
TC2N
tandem C2 domains, nuclear
chr5_+_93954358 1.27 ENST00000504099.1
ANKRD32
ankyrin repeat domain 32
chr3_+_50654821 1.27 ENST00000457064.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr5_+_61602236 1.22 ENST00000514082.1
ENST00000407818.3
KIF2A
kinesin heavy chain member 2A
chr17_-_10101868 1.19 ENST00000432992.2
ENST00000540214.1
GAS7
growth arrest-specific 7
chr5_-_100238918 1.19 ENST00000451528.2
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr11_+_1860200 1.14 ENST00000381911.1
TNNI2
troponin I type 2 (skeletal, fast)
chr20_+_825275 1.07 ENST00000541082.1
FAM110A
family with sequence similarity 110, member A
chr20_-_58515344 1.07 ENST00000370996.3
PPP1R3D
protein phosphatase 1, regulatory subunit 3D
chr3_+_50654550 1.06 ENST00000430409.1
ENST00000357955.2
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr15_+_78556809 1.05 ENST00000343789.3
ENST00000394852.3
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr15_+_83776137 1.04 ENST00000322019.9
TM6SF1
transmembrane 6 superfamily member 1
chr14_-_51297197 1.02 ENST00000382043.4
NIN
ninein (GSK3B interacting protein)
chr8_+_38243951 1.00 ENST00000297720.5
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr5_+_61602055 1.00 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr13_-_46961365 1.00 ENST00000417405.1
ENST00000378784.4
ENST00000534925.1
KIAA0226L
KIAA0226-like
chr15_+_83776324 0.99 ENST00000379390.6
ENST00000379386.4
ENST00000565774.1
ENST00000565982.1
TM6SF1
transmembrane 6 superfamily member 1
chr19_-_6424283 0.99 ENST00000595258.1
ENST00000595548.1
KHSRP
KH-type splicing regulatory protein
chr3_+_52279737 0.97 ENST00000457351.2
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr13_-_46961580 0.97 ENST00000378787.3
ENST00000378797.2
ENST00000429979.1
ENST00000378781.3
KIAA0226L
KIAA0226-like
chr5_-_100238956 0.95 ENST00000231461.5
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr3_+_52279902 0.95 ENST00000457454.1
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr3_+_47021168 0.92 ENST00000450053.3
ENST00000292309.5
ENST00000383740.2
NBEAL2
neurobeachin-like 2
chr2_+_28113583 0.91 ENST00000344773.2
ENST00000379624.1
ENST00000342045.2
ENST00000379632.2
ENST00000361704.2
BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr11_-_65429891 0.91 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr5_+_176873789 0.90 ENST00000323249.3
ENST00000502922.1
PRR7
proline rich 7 (synaptic)
chr14_-_51297837 0.90 ENST00000245441.5
ENST00000389868.3
ENST00000382041.3
ENST00000324330.9
ENST00000453196.1
ENST00000453401.2
NIN
ninein (GSK3B interacting protein)
chr13_-_46961317 0.89 ENST00000322896.6
KIAA0226L
KIAA0226-like
chr1_+_117544366 0.89 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr5_+_61601965 0.88 ENST00000401507.3
KIF2A
kinesin heavy chain member 2A
chr2_+_46770531 0.88 ENST00000482449.2
RHOQ
ras homolog family member Q
chr20_-_31172598 0.87 ENST00000201961.2
C20orf112
chromosome 20 open reading frame 112
chr1_+_101361782 0.84 ENST00000357650.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr17_+_7387919 0.83 ENST00000572844.1
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr17_+_7338737 0.82 ENST00000323206.1
ENST00000396568.1
TMEM102
transmembrane protein 102
chr15_-_83735889 0.82 ENST00000379403.2
BTBD1
BTB (POZ) domain containing 1
chr5_+_154238149 0.81 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CNOT8
CCR4-NOT transcription complex, subunit 8
chr5_-_131892501 0.81 ENST00000450655.1
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr5_+_80256453 0.80 ENST00000265080.4
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr12_+_51632666 0.80 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr11_+_12132117 0.78 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr6_+_30457244 0.78 ENST00000376630.4
HLA-E
major histocompatibility complex, class I, E
chr15_+_34260921 0.77 ENST00000560035.1
CHRM5
cholinergic receptor, muscarinic 5
chr2_+_113403434 0.77 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr5_+_112312399 0.76 ENST00000515408.1
ENST00000513585.1
DCP2
decapping mRNA 2
chr3_+_14989186 0.76 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chrX_-_153775760 0.75 ENST00000440967.1
ENST00000393564.2
ENST00000369620.2
G6PD
glucose-6-phosphate dehydrogenase
chr12_+_123259063 0.74 ENST00000392441.4
ENST00000539171.1
CCDC62
coiled-coil domain containing 62
chr12_+_51632638 0.74 ENST00000549732.2
DAZAP2
DAZ associated protein 2
chr3_-_197463590 0.73 ENST00000296343.5
ENST00000389665.5
ENST00000449205.1
KIAA0226
KIAA0226
chr10_+_127585093 0.73 ENST00000368695.1
ENST00000368693.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr6_+_29910301 0.73 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr2_+_201981663 0.72 ENST00000433445.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr12_-_54071181 0.71 ENST00000338662.5
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr17_+_62075703 0.71 ENST00000577953.1
ENST00000582540.1
ENST00000579184.1
ENST00000425164.3
ENST00000412177.1
ENST00000539996.1
ENST00000583891.1
ENST00000580752.1
C17orf72
chromosome 17 open reading frame 72
chr3_+_52280220 0.70 ENST00000409502.3
ENST00000323588.4
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chrX_-_19905703 0.70 ENST00000397821.3
SH3KBP1
SH3-domain kinase binding protein 1
chr5_-_1524015 0.70 ENST00000283415.3
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr10_-_125851961 0.69 ENST00000346248.5
CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr17_+_33914424 0.68 ENST00000590432.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr9_+_97136833 0.67 ENST00000375344.3
HIATL1
hippocampus abundant transcript-like 1
chr6_-_38607628 0.66 ENST00000498633.1
BTBD9
BTB (POZ) domain containing 9
chr12_-_102224457 0.66 ENST00000549165.1
ENST00000549940.1
ENST00000392919.4
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr15_+_89905705 0.66 ENST00000560008.1
ENST00000561327.1
LINC00925
long intergenic non-protein coding RNA 925
chr5_-_83016632 0.65 ENST00000515590.1
HAPLN1
hyaluronan and proteoglycan link protein 1
chr17_-_7387524 0.65 ENST00000311403.4
ZBTB4
zinc finger and BTB domain containing 4
chr13_-_95364389 0.65 ENST00000376945.2
SOX21
SRY (sex determining region Y)-box 21
chr3_+_52280173 0.65 ENST00000296487.4
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr2_-_142888573 0.64 ENST00000434794.1
LRP1B
low density lipoprotein receptor-related protein 1B
chr19_+_19516561 0.64 ENST00000457895.2
GATAD2A
GATA zinc finger domain containing 2A
chr19_+_7599792 0.64 ENST00000600942.1
ENST00000593924.1
PNPLA6
patatin-like phospholipase domain containing 6
chr12_-_22487588 0.64 ENST00000381424.3
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr18_+_9708162 0.64 ENST00000578921.1
RAB31
RAB31, member RAS oncogene family
chr19_+_7599597 0.64 ENST00000414982.3
ENST00000450331.3
PNPLA6
patatin-like phospholipase domain containing 6
chr6_-_150039170 0.61 ENST00000458696.2
ENST00000392273.3
LATS1
large tumor suppressor kinase 1
chr1_-_78444776 0.61 ENST00000370767.1
ENST00000421641.1
FUBP1
far upstream element (FUSE) binding protein 1
chr6_+_117586713 0.60 ENST00000352536.3
ENST00000326274.5
VGLL2
vestigial like 2 (Drosophila)
chr1_-_78444738 0.60 ENST00000436586.2
ENST00000370768.2
FUBP1
far upstream element (FUSE) binding protein 1
chr14_+_70078303 0.60 ENST00000342745.4
KIAA0247
KIAA0247
chr16_-_30022293 0.60 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
DOC2A
double C2-like domains, alpha
chr17_-_58469329 0.60 ENST00000393003.3
USP32
ubiquitin specific peptidase 32
chr20_+_58515417 0.60 ENST00000360816.3
FAM217B
family with sequence similarity 217, member B
chr6_-_26285737 0.59 ENST00000377727.1
ENST00000289352.1
HIST1H4H
histone cluster 1, H4h
chr17_-_43510282 0.59 ENST00000290470.3
ARHGAP27
Rho GTPase activating protein 27
chr12_+_51632600 0.59 ENST00000549555.1
ENST00000439799.2
ENST00000425012.2
DAZAP2
DAZ associated protein 2
chr5_-_140998616 0.58 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1
diaphanous-related formin 1
chr2_+_30670209 0.58 ENST00000497423.1
ENST00000476535.1
LCLAT1
lysocardiolipin acyltransferase 1
chr17_+_76037081 0.57 ENST00000588549.1
TNRC6C
trinucleotide repeat containing 6C
chr21_+_17102311 0.57 ENST00000285679.6
ENST00000351097.5
ENST00000285681.2
ENST00000400183.2
USP25
ubiquitin specific peptidase 25
chr12_-_102224704 0.57 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr17_+_36508826 0.57 ENST00000580660.1
SOCS7
suppressor of cytokine signaling 7
chr6_-_111136299 0.57 ENST00000457688.1
CDK19
cyclin-dependent kinase 19
chr19_-_37663572 0.57 ENST00000588354.1
ENST00000292841.5
ENST00000355533.2
ENST00000356958.4
ZNF585A
zinc finger protein 585A
chr19_+_39897943 0.56 ENST00000600033.1
ZFP36
ZFP36 ring finger protein
chr19_+_14544099 0.56 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1
protein kinase N1
chr19_+_7599128 0.56 ENST00000545201.2
PNPLA6
patatin-like phospholipase domain containing 6
chr5_+_154238042 0.56 ENST00000519211.1
ENST00000522458.1
ENST00000519903.1
ENST00000521450.1
ENST00000403027.2
CNOT8
CCR4-NOT transcription complex, subunit 8
chr15_-_55700457 0.56 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
CCPG1
cell cycle progression 1
chr8_+_31496809 0.55 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr1_-_40562908 0.55 ENST00000527311.2
ENST00000449045.2
ENST00000372779.4
PPT1
palmitoyl-protein thioesterase 1
chr18_-_60985914 0.54 ENST00000589955.1
BCL2
B-cell CLL/lymphoma 2
chr13_-_46626820 0.53 ENST00000428921.1
ZC3H13
zinc finger CCCH-type containing 13
chr10_+_14880287 0.53 ENST00000437161.2
HSPA14
heat shock 70kDa protein 14
chrX_-_19905577 0.53 ENST00000379697.3
SH3KBP1
SH3-domain kinase binding protein 1
chr12_-_110318130 0.52 ENST00000540772.1
GLTP
glycolipid transfer protein
chr17_-_58469591 0.52 ENST00000589335.1
USP32
ubiquitin specific peptidase 32
chr19_-_10444188 0.52 ENST00000293677.6
RAVER1
ribonucleoprotein, PTB-binding 1
chr22_+_29469100 0.52 ENST00000327813.5
ENST00000407188.1
KREMEN1
kringle containing transmembrane protein 1
chr8_-_11058847 0.52 ENST00000297303.4
ENST00000416569.2
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr4_+_81256871 0.51 ENST00000358105.3
ENST00000508675.1
C4orf22
chromosome 4 open reading frame 22
chrX_-_106959631 0.51 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chr19_-_49496557 0.51 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
GYS1
glycogen synthase 1 (muscle)
chr15_-_78423567 0.51 ENST00000561190.1
ENST00000559645.1
ENST00000560618.1
ENST00000559054.1
CIB2
calcium and integrin binding family member 2
chr5_+_154237778 0.51 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
CNOT8
CCR4-NOT transcription complex, subunit 8
chr12_+_51632508 0.50 ENST00000449723.3
DAZAP2
DAZ associated protein 2
chr18_+_48405463 0.50 ENST00000382927.3
ME2
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr10_+_70715884 0.50 ENST00000354185.4
DDX21
DEAD (Asp-Glu-Ala-Asp) box helicase 21
chr2_-_38829768 0.50 ENST00000378915.3
HNRNPLL
heterogeneous nuclear ribonucleoprotein L-like
chr17_-_58469687 0.50 ENST00000590133.1
USP32
ubiquitin specific peptidase 32
chr7_+_76751926 0.50 ENST00000285871.4
ENST00000431197.1
CCDC146
coiled-coil domain containing 146
chr5_+_149340339 0.50 ENST00000433184.1
SLC26A2
solute carrier family 26 (anion exchanger), member 2
chr5_+_154238096 0.49 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
CNOT8
CCR4-NOT transcription complex, subunit 8
chr10_-_27529779 0.48 ENST00000426079.1
ACBD5
acyl-CoA binding domain containing 5
chr4_+_119199904 0.48 ENST00000602483.1
ENST00000602819.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr16_-_75498308 0.48 ENST00000569540.1
TMEM170A
transmembrane protein 170A
chr1_-_47697387 0.48 ENST00000371884.2
TAL1
T-cell acute lymphocytic leukemia 1
chr20_+_4129496 0.48 ENST00000346595.2
SMOX
spermine oxidase
chr18_+_48405419 0.47 ENST00000321341.5
ME2
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr2_-_38830030 0.47 ENST00000410076.1
HNRNPLL
heterogeneous nuclear ribonucleoprotein L-like
chr1_+_101361626 0.47 ENST00000370112.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr1_+_221054411 0.46 ENST00000427693.1
HLX
H2.0-like homeobox
chr20_-_31124186 0.46 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr9_-_99775862 0.46 ENST00000602917.1
ENST00000375223.4
HIATL2
hippocampus abundant transcript-like 2
chr1_-_8939265 0.45 ENST00000489867.1
ENO1
enolase 1, (alpha)
chrX_+_15756382 0.45 ENST00000318636.3
CA5B
carbonic anhydrase VB, mitochondrial
chr10_-_52383644 0.44 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chr10_+_14880364 0.44 ENST00000441647.1
HSPA14
heat shock 70kDa protein 14
chr17_-_16395455 0.44 ENST00000409083.3
FAM211A
family with sequence similarity 211, member A
chr12_-_110318226 0.44 ENST00000544393.1
GLTP
glycolipid transfer protein
chr1_+_40627038 0.43 ENST00000372771.4
RLF
rearranged L-myc fusion
chr5_-_140998481 0.43 ENST00000518047.1
DIAPH1
diaphanous-related formin 1
chr19_-_47220335 0.43 ENST00000601806.1
ENST00000593363.1
ENST00000598633.1
ENST00000595515.1
ENST00000433867.1
PRKD2
protein kinase D2
chr11_+_61447845 0.43 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr12_-_22487618 0.42 ENST00000404299.3
ENST00000396037.4
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr3_-_195163584 0.42 ENST00000439666.1
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr3_-_27525865 0.42 ENST00000445684.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr3_+_156393349 0.42 ENST00000473702.1
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr20_+_4129426 0.42 ENST00000339123.6
ENST00000305958.4
ENST00000278795.3
SMOX
spermine oxidase
chr17_+_29421987 0.42 ENST00000431387.4
NF1
neurofibromin 1
chr7_-_130353553 0.41 ENST00000330992.7
ENST00000445977.2
COPG2
coatomer protein complex, subunit gamma 2
chr17_+_7387677 0.41 ENST00000322644.6
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr5_-_150138246 0.41 ENST00000518015.1
DCTN4
dynactin 4 (p62)
chr2_+_241508039 0.40 ENST00000270357.4
RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr2_-_38830090 0.40 ENST00000449105.3
HNRNPLL
heterogeneous nuclear ribonucleoprotein L-like
chr12_+_57943781 0.40 ENST00000455537.2
ENST00000286452.5
KIF5A
kinesin family member 5A
chr11_-_73882249 0.40 ENST00000535954.1
C2CD3
C2 calcium-dependent domain containing 3
chr2_-_241759622 0.40 ENST00000320389.7
ENST00000498729.2
KIF1A
kinesin family member 1A
chr1_+_221054584 0.40 ENST00000549319.1
HLX
H2.0-like homeobox
chr4_+_119199864 0.39 ENST00000602414.1
ENST00000602520.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr2_-_38829990 0.39 ENST00000409328.1
HNRNPLL
heterogeneous nuclear ribonucleoprotein L-like
chr2_-_128785619 0.39 ENST00000450957.1
SAP130
Sin3A-associated protein, 130kDa
chr1_-_235491462 0.38 ENST00000418304.1
ENST00000264183.3
ENST00000349213.3
ARID4B
AT rich interactive domain 4B (RBP1-like)
chr16_+_30772913 0.38 ENST00000563909.1
RNF40
ring finger protein 40, E3 ubiquitin protein ligase
chr6_+_30035307 0.38 ENST00000376765.2
ENST00000376763.1
PPP1R11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr5_-_99870890 0.38 ENST00000499025.1
CTD-2001C12.1
CTD-2001C12.1
chr19_+_38755237 0.38 ENST00000587516.1
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr15_+_76135622 0.38 ENST00000338677.4
ENST00000267938.4
ENST00000569423.1
UBE2Q2
ubiquitin-conjugating enzyme E2Q family member 2
chr2_-_219906220 0.38 ENST00000458526.1
ENST00000409865.3
ENST00000410037.1
ENST00000457968.1
ENST00000436631.1
ENST00000341552.5
ENST00000441968.1
ENST00000295729.2
CCDC108
coiled-coil domain containing 108
chr3_-_195163803 0.38 ENST00000326793.6
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr14_+_54863739 0.38 ENST00000541304.1
CDKN3
cyclin-dependent kinase inhibitor 3
chr3_-_150481218 0.37 ENST00000482706.1
SIAH2
siah E3 ubiquitin protein ligase 2
chr4_-_170533723 0.37 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
NEK1
NIMA-related kinase 1
chr15_-_55700522 0.37 ENST00000564092.1
ENST00000310958.6
CCPG1
cell cycle progression 1
chr2_+_10560147 0.37 ENST00000422133.1
HPCAL1
hippocalcin-like 1
chr2_+_168149569 0.37 ENST00000442316.1
AC074363.1
AC074363.1
chr11_+_64059464 0.37 ENST00000394525.2
KCNK4
potassium channel, subfamily K, member 4
chr17_-_58469474 0.36 ENST00000300896.4
USP32
ubiquitin specific peptidase 32
chr12_+_3600356 0.36 ENST00000382622.3
PRMT8
protein arginine methyltransferase 8
chr2_-_152684977 0.36 ENST00000428992.2
ENST00000295087.8
ARL5A
ADP-ribosylation factor-like 5A
chr17_-_56065540 0.36 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr13_-_21635631 0.35 ENST00000382592.4
LATS2
large tumor suppressor kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXN1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
1.2 3.5 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.4 1.2 GO:0001172 transcription, RNA-templated(GO:0001172)
0.4 1.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.3 0.9 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.3 0.8 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.3 0.8 GO:0042270 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2 0.7 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.2 0.7 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.2 1.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.2 1.6 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2 1.0 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.2 0.8 GO:0019417 sulfur oxidation(GO:0019417)
0.2 3.7 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.2 1.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.5 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.1 2.3 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.7 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 1.0 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.5 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.9 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.8 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 1.4 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 2.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.6 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.1 1.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 1.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.4 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.9 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.6 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.8 GO:0046836 glycolipid transport(GO:0046836)
0.1 0.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.4 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.4 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.8 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.1 1.0 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.7 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.2 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 2.4 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 0.3 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.5 GO:0002084 protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549)
0.1 0.3 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.1 3.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.7 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.2 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.1 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.1 0.3 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.4 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.1 0.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.7 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.6 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.6 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.1 0.2 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 0.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.5 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.8 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.4 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 2.0 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.4 GO:0072553 terminal button organization(GO:0072553)
0.0 0.2 GO:2001279 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.0 0.6 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.4 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 1.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.7 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 1.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0097319 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.2 GO:1902903 regulation of fibril organization(GO:1902903)
0.0 1.1 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.9 GO:0071318 cellular response to ATP(GO:0071318)
0.0 3.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.8 GO:0051292 nuclear pore complex assembly(GO:0051292) endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 1.9 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.2 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.6 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 1.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.8 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.9 GO:0030220 platelet formation(GO:0030220)
0.0 0.6 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.8 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 3.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.4 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.0 0.4 GO:0015074 DNA integration(GO:0015074)
0.0 0.3 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 2.0 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.1 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097)
0.0 0.2 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.3 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 1.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.7 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 1.2 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.6 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.9 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 0.9 GO:0015701 bicarbonate transport(GO:0015701)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.3 0.9 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.2 3.5 GO:0036449 microtubule minus-end(GO:0036449)
0.2 2.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 0.9 GO:0005927 muscle tendon junction(GO:0005927)
0.1 1.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.3 GO:0008623 CHRAC(GO:0008623)
0.1 0.3 GO:0044753 amphisome(GO:0044753)
0.1 0.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.1 GO:0042587 glycogen granule(GO:0042587)
0.1 3.1 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.2 GO:0039713 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 0.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.1 1.2 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.7 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 1.1 GO:0005861 troponin complex(GO:0005861)
0.0 1.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.0 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.8 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.0 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 2.8 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.7 GO:0000922 spindle pole(GO:0000922)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0030673 axolemma(GO:0030673)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0032427 GBD domain binding(GO:0032427)
0.4 1.2 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.4 1.6 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.4 1.9 GO:0070051 fibrinogen binding(GO:0070051)
0.3 3.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 1.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.3 0.9 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.3 0.8 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.3 3.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 6.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 0.7 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 0.6 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.2 1.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 1.0 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 0.6 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.7 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 1.0 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.4 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.9 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.8 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.6 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.4 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 0.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.3 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.4 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 2.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.8 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 1.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.5 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.1 GO:0031014 troponin T binding(GO:0031014)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.5 GO:0043426 MRF binding(GO:0043426)
0.1 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 3.8 GO:0043022 ribosome binding(GO:0043022)
0.0 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 2.8 GO:0050699 WW domain binding(GO:0050699)
0.0 1.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 3.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 2.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0032406 purine-specific mismatch base pair DNA N-glycosylase activity(GO:0000701) MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.3 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 2.7 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 5.6 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 2.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.0 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.6 REACTOME KINESINS Genes involved in Kinesins
0.1 0.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.9 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.9 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 0.6 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 2.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 3.7 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 1.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 2.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends