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Illumina Body Map 2, young vs old

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Results for FOXQ1

Z-value: 0.25

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Transcription factors associated with FOXQ1

Gene Symbol Gene ID Gene Info
ENSG00000164379.4 forkhead box Q1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXQ1hg19_v2_chr6_+_1312675_13127010.522.4e-03Click!

Activity profile of FOXQ1 motif

Sorted Z-values of FOXQ1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_107020963 4.13 ENST00000509000.2
nuclear cap binding protein subunit 2-like
chr6_-_52628271 3.77 ENST00000493422.1
glutathione S-transferase alpha 2
chr11_-_26593649 3.06 ENST00000455601.2
mucin 15, cell surface associated
chr12_-_91574142 3.00 ENST00000547937.1
decorin
chr6_-_52774464 2.82 ENST00000370968.1
ENST00000211122.3
glutathione S-transferase alpha 3
chr21_-_31588365 2.69 ENST00000399899.1
claudin 8
chr11_-_26593779 2.67 ENST00000529533.1
mucin 15, cell surface associated
chr11_-_26593677 2.60 ENST00000527569.1
mucin 15, cell surface associated
chr21_-_31588338 2.54 ENST00000286809.1
claudin 8
chrX_+_105936982 2.36 ENST00000418562.1
ring finger protein 128, E3 ubiquitin protein ligase
chr6_-_87804815 2.24 ENST00000369582.2
glycoprotein hormones, alpha polypeptide
chr1_-_178840157 2.21 ENST00000367629.1
ENST00000234816.2
angiopoietin-like 1
chr6_-_52668605 2.20 ENST00000334575.5
glutathione S-transferase alpha 1
chr5_-_13944652 2.20 ENST00000265104.4
dynein, axonemal, heavy chain 5
chr12_-_71551652 2.17 ENST00000546561.1
tetraspanin 8
chr5_+_94727048 2.12 ENST00000283357.5
family with sequence similarity 81, member B
chr3_+_193853927 2.09 ENST00000232424.3
hes family bHLH transcription factor 1
chr13_+_76413852 2.04 ENST00000533809.2
LIM domain 7
chr2_+_47596287 2.04 ENST00000263735.4
epithelial cell adhesion molecule
chr5_+_140529630 1.77 ENST00000543635.1
protocadherin beta 6
chrX_+_105192423 1.74 ENST00000540278.1
Nik related kinase
chr17_+_72426891 1.71 ENST00000392627.1
G protein-coupled receptor, family C, group 5, member C
chr6_-_49712123 1.68 ENST00000263045.4
cysteine-rich secretory protein 3
chr11_+_101983176 1.66 ENST00000524575.1
Yes-associated protein 1
chr6_+_30856507 1.61 ENST00000513240.1
ENST00000424544.2
discoidin domain receptor tyrosine kinase 1
chr6_-_49681235 1.56 ENST00000339139.4
cysteine-rich secretory protein 2
chr6_-_49712147 1.54 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr6_+_131958436 1.53 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr2_+_108994633 1.52 ENST00000409309.3
sulfotransferase family, cytosolic, 1C, member 4
chr11_+_60467047 1.51 ENST00000300226.2
membrane-spanning 4-domains, subfamily A, member 8
chr9_-_35563896 1.51 ENST00000399742.2
family with sequence similarity 166, member B
chr5_+_140625147 1.48 ENST00000231173.3
protocadherin beta 15
chr4_-_119274121 1.41 ENST00000296498.3
protease, serine, 12 (neurotrypsin, motopsin)
chr5_+_78985673 1.40 ENST00000446378.2
cardiomyopathy associated 5
chr3_-_100565249 1.39 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI family, member 3 (NESH) binding protein
chr6_-_49712072 1.38 ENST00000423399.2
cysteine-rich secretory protein 3
chr5_+_140588269 1.35 ENST00000541609.1
ENST00000239450.2
protocadherin beta 12
chr2_+_74120094 1.30 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
actin, gamma 2, smooth muscle, enteric
chr10_-_91295304 1.30 ENST00000341233.4
ENST00000371790.4
solute carrier family 16, member 12
chr1_-_198509804 1.29 ENST00000489986.1
ENST00000367382.1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
chr3_+_69811858 1.28 ENST00000433517.1
microphthalmia-associated transcription factor
chr5_+_73109339 1.25 ENST00000296799.4
Rho guanine nucleotide exchange factor (GEF) 28
chr2_+_79252804 1.24 ENST00000393897.2
regenerating islet-derived 3 gamma
chr2_+_79252822 1.23 ENST00000272324.5
regenerating islet-derived 3 gamma
chr18_-_30716038 1.23 ENST00000581852.1
coiled-coil domain containing 178
chr15_-_95676078 1.17 ENST00000554787.1
RP11-255M2.2
chr13_-_39564993 1.17 ENST00000423210.1
stomatin (EPB72)-like 3
chr20_+_31805131 1.16 ENST00000375454.3
ENST00000375452.3
BPI fold containing family A, member 3
chr6_-_28973037 1.15 ENST00000377179.3
zinc finger protein 311
chr8_+_92261516 1.14 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr16_-_15950868 1.14 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
myosin, heavy chain 11, smooth muscle
chr6_-_160679905 1.12 ENST00000366953.3
solute carrier family 22 (organic cation transporter), member 2
chr15_-_56757329 1.11 ENST00000260453.3
meiosis-specific nuclear structural 1
chr5_+_140579162 1.11 ENST00000536699.1
ENST00000354757.3
protocadherin beta 11
chr8_-_16424871 1.10 ENST00000518026.1
macrophage scavenger receptor 1
chr20_+_34802295 1.10 ENST00000432603.1
erythrocyte membrane protein band 4.1-like 1
chr14_+_77843459 1.09 ENST00000216471.4
sterile alpha motif domain containing 15
chr10_-_4285923 1.09 ENST00000418372.1
ENST00000608792.1
long intergenic non-protein coding RNA 702
chr12_+_19358228 1.07 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr5_-_41261540 1.06 ENST00000263413.3
complement component 6
chr12_+_19358192 1.06 ENST00000538305.1
pleckstrin homology domain containing, family A member 5
chr8_+_55528627 1.05 ENST00000220676.1
retinitis pigmentosa 1 (autosomal dominant)
chr6_-_52710893 1.04 ENST00000284562.2
glutathione S-transferase alpha 5
chr9_+_124922171 1.04 ENST00000373764.3
ENST00000536616.1
MORN repeat containing 5
chr6_-_49712091 1.04 ENST00000371159.4
cysteine-rich secretory protein 3
chr1_+_239882842 1.03 ENST00000448020.1
cholinergic receptor, muscarinic 3
chr1_-_117210290 1.03 ENST00000369483.1
ENST00000369486.3
immunoglobulin superfamily, member 3
chr14_+_24867992 1.03 ENST00000382554.3
NYN domain and retroviral integrase containing
chr5_+_38403637 1.03 ENST00000336740.6
ENST00000397202.2
EGF-like, fibronectin type III and laminin G domains
chr19_+_7580103 1.02 ENST00000596712.1
zinc finger protein 358
chrX_-_9734004 1.01 ENST00000467482.1
ENST00000380929.2
G protein-coupled receptor 143
chr10_+_127661942 1.01 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
fibronectin type III and ankyrin repeat domains 1
chr1_+_162602244 1.01 ENST00000367922.3
ENST00000367921.3
discoidin domain receptor tyrosine kinase 2
chr17_-_19648683 1.00 ENST00000573368.1
ENST00000457500.2
aldehyde dehydrogenase 3 family, member A1
chr2_-_188419078 0.98 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr7_+_48211048 0.98 ENST00000435803.1
ATP-binding cassette, sub-family A (ABC1), member 13
chr1_-_178838404 0.98 ENST00000444255.1
angiopoietin-like 1
chr10_+_75668916 0.97 ENST00000481390.1
plasminogen activator, urokinase
chr4_+_75174180 0.96 ENST00000413830.1
epithelial mitogen
chr1_-_151148442 0.94 ENST00000441701.1
ENST00000416280.2
tropomodulin 4 (muscle)
chr12_-_71551868 0.94 ENST00000247829.3
tetraspanin 8
chr7_+_134528635 0.93 ENST00000445569.2
caldesmon 1
chr1_-_216978709 0.93 ENST00000360012.3
estrogen-related receptor gamma
chr1_-_182921119 0.92 ENST00000423786.1
SHC SH2-domain binding protein 1-like
chr18_+_61143994 0.92 ENST00000382771.4
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr2_+_201450591 0.92 ENST00000374700.2
aldehyde oxidase 1
chr12_-_18243119 0.92 ENST00000538724.1
ENST00000229002.2
RERG/RAS-like
chr14_-_61191049 0.92 ENST00000556952.3
SIX homeobox 4
chr2_+_79252834 0.91 ENST00000409471.1
regenerating islet-derived 3 gamma
chr4_-_47983519 0.91 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chr11_+_34654011 0.91 ENST00000531794.1
ets homologous factor
chr6_+_24357131 0.90 ENST00000274766.1
kidney associated antigen 1
chr21_-_27945562 0.90 ENST00000299340.4
ENST00000435845.2
cysteine/tyrosine-rich 1
chr12_-_11036844 0.90 ENST00000428168.2
proline-rich protein HaeIII subfamily 1
chr7_-_81635106 0.89 ENST00000443883.1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr11_+_73019282 0.89 ENST00000263674.3
Rho guanine nucleotide exchange factor (GEF) 17
chr4_+_15341442 0.89 ENST00000397700.2
ENST00000295297.4
C1q and tumor necrosis factor related protein 7
chr3_-_100558953 0.89 ENST00000533795.1
ABI family, member 3 (NESH) binding protein
chr1_-_99999571 0.88 ENST00000438829.2
RP11-413P11.1
chr14_+_93389425 0.88 ENST00000216492.5
ENST00000334654.4
chromogranin A (parathyroid secretory protein 1)
chr3_+_154801678 0.87 ENST00000462837.1
membrane metallo-endopeptidase
chr3_+_174577070 0.87 ENST00000454872.1
N-acetylated alpha-linked acidic dipeptidase-like 2
chr1_-_153599732 0.86 ENST00000392623.1
S100 calcium binding protein A13
chr1_+_145525015 0.86 ENST00000539363.1
ENST00000538811.1
integrin, alpha 10
chr11_-_85397167 0.86 ENST00000316398.3
coiled-coil domain containing 89
chrX_+_9880412 0.85 ENST00000418909.2
shroom family member 2
chr4_-_185139062 0.84 ENST00000296741.2
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr12_-_63753817 0.84 ENST00000551729.1
RP11-1022B3.1
chr20_+_12989596 0.84 ENST00000434210.1
ENST00000399002.2
serine palmitoyltransferase, long chain base subunit 3
chr2_-_175629135 0.84 ENST00000409542.1
ENST00000409219.1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr1_+_171060018 0.84 ENST00000367755.4
ENST00000392085.2
ENST00000542847.1
ENST00000538429.1
ENST00000479749.1
flavin containing monooxygenase 3
chr8_-_49834299 0.83 ENST00000396822.1
snail family zinc finger 2
chr6_-_168479839 0.83 ENST00000283309.6
FERM domain containing 1
chr18_+_7754957 0.83 ENST00000400053.4
protein tyrosine phosphatase, receptor type, M
chr2_-_188419200 0.83 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr3_+_189349162 0.82 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
tumor protein p63
chr9_-_14910990 0.82 ENST00000380881.4
ENST00000422223.2
FRAS1 related extracellular matrix 1
chr6_+_125524785 0.82 ENST00000392482.2
tumor protein D52-like 1
chr4_+_111397216 0.81 ENST00000265162.5
glutamyl aminopeptidase (aminopeptidase A)
chr15_+_71839566 0.81 ENST00000357769.4
thrombospondin, type I, domain containing 4
chr13_+_22245522 0.81 ENST00000382353.5
fibroblast growth factor 9
chr14_-_36990061 0.80 ENST00000546983.1
NK2 homeobox 1
chr3_+_69985792 0.80 ENST00000531774.1
microphthalmia-associated transcription factor
chr2_-_157198860 0.80 ENST00000409572.1
nuclear receptor subfamily 4, group A, member 2
chr3_-_155011483 0.80 ENST00000489090.1
RP11-451G4.2
chr5_+_121465207 0.79 ENST00000296600.4
zinc finger protein 474
chr4_-_186696425 0.79 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chr1_+_16083154 0.79 ENST00000375771.1
filamin binding LIM protein 1
chr13_+_76378407 0.78 ENST00000447038.1
LIM domain 7
chr3_+_69985734 0.78 ENST00000314557.6
ENST00000394351.3
microphthalmia-associated transcription factor
chr11_+_86106208 0.78 ENST00000528728.1
coiled-coil domain containing 81
chr5_+_140743859 0.78 ENST00000518069.1
protocadherin gamma subfamily A, 5
chr1_+_16083098 0.78 ENST00000496928.2
ENST00000508310.1
filamin binding LIM protein 1
chr8_+_70404996 0.77 ENST00000402687.4
ENST00000419716.3
sulfatase 1
chr1_-_151148492 0.76 ENST00000295314.4
tropomodulin 4 (muscle)
chr4_+_95916947 0.76 ENST00000506363.1
bone morphogenetic protein receptor, type IB
chr15_+_50474385 0.75 ENST00000267842.5
solute carrier family 27 (fatty acid transporter), member 2
chr4_+_40751914 0.74 ENST00000381782.2
ENST00000316607.5
NOP2/Sun domain family, member 7
chr6_+_127898312 0.74 ENST00000329722.7
chromosome 6 open reading frame 58
chr3_+_2933893 0.74 ENST00000397459.2
contactin 4
chr19_-_48823332 0.73 ENST00000315396.7
coiled-coil domain containing 114
chr4_-_10686373 0.73 ENST00000442825.2
cytokine-dependent hematopoietic cell linker
chr3_+_182983090 0.73 ENST00000465010.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr16_-_10652993 0.72 ENST00000536829.1
epithelial membrane protein 2
chr8_+_133975231 0.72 ENST00000518058.1
thyroglobulin
chr10_-_49482907 0.72 ENST00000374201.3
ENST00000407470.4
FERM and PDZ domain containing 2
chr16_+_4784273 0.72 ENST00000299320.5
ENST00000586724.1
chromosome 16 open reading frame 71
chr17_-_46690839 0.72 ENST00000498634.2
homeobox B8
chr2_-_151344172 0.72 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr19_-_39402798 0.72 ENST00000571838.1
coiled-coil glutamate-rich protein 2
chr12_+_122880045 0.70 ENST00000539034.1
ENST00000535976.1
RP11-450K4.1
chr5_+_72921983 0.70 ENST00000296794.6
ENST00000545377.1
ENST00000513042.2
ENST00000287898.5
ENST00000509848.1
Rho guanine nucleotide exchange factor (GEF) 28
chr5_+_42423872 0.70 ENST00000230882.4
ENST00000357703.3
growth hormone receptor
chr18_+_61254570 0.69 ENST00000344731.5
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chrX_-_9734038 0.69 ENST00000431126.1
G protein-coupled receptor 143
chr3_+_53528659 0.69 ENST00000350061.5
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr12_-_120763739 0.69 ENST00000549767.1
phospholipase A2, group IB (pancreas)
chr1_+_171154347 0.69 ENST00000209929.7
ENST00000441535.1
flavin containing monooxygenase 2 (non-functional)
chr22_-_36236623 0.69 ENST00000405409.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr11_-_110561721 0.69 ENST00000357139.3
Rho GTPase activating protein 20
chr7_+_128349106 0.69 ENST00000485070.1
family with sequence similarity 71, member F1
chr2_+_108994466 0.68 ENST00000272452.2
sulfotransferase family, cytosolic, 1C, member 4
chr1_-_94079648 0.68 ENST00000370247.3
breast cancer anti-estrogen resistance 3
chr5_+_121465234 0.68 ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr7_-_122342988 0.68 ENST00000434824.1
ring finger protein 148
chr1_+_145524891 0.68 ENST00000369304.3
integrin, alpha 10
chr1_-_227505289 0.67 ENST00000366765.3
CDC42 binding protein kinase alpha (DMPK-like)
chr6_-_49834240 0.66 ENST00000335847.4
cysteine-rich secretory protein 1
chr2_+_158114051 0.66 ENST00000259056.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr8_+_112388852 0.66 ENST00000521904.1
ENST00000521753.1
RP11-1101K5.1
chr15_-_51535208 0.66 ENST00000405913.3
ENST00000559878.1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr2_-_180427304 0.65 ENST00000336917.5
zinc finger protein 385B
chr16_+_4784458 0.65 ENST00000590191.1
chromosome 16 open reading frame 71
chr7_-_41742697 0.65 ENST00000242208.4
inhibin, beta A
chr15_+_86685227 0.65 ENST00000441037.2
ATP/GTP binding protein-like 1
chr14_-_58618896 0.65 ENST00000267485.7
chromosome 14 open reading frame 37
chr8_-_49833978 0.65 ENST00000020945.1
snail family zinc finger 2
chr18_+_61254534 0.64 ENST00000269489.5
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr12_+_81664424 0.64 ENST00000549161.1
ENST00000550138.1
RP11-121G22.3
chr3_-_19975665 0.64 ENST00000295824.9
ENST00000389256.4
EF-hand domain family, member B
chr14_-_81916501 0.64 ENST00000555001.1
RP11-299L17.3
chr6_-_52705641 0.64 ENST00000370989.2
glutathione S-transferase alpha 5
chr21_-_26797019 0.64 ENST00000440205.1
long intergenic non-protein coding RNA 158
chr2_-_31030277 0.64 ENST00000534090.2
ENST00000295055.8
calpain 13
chr4_+_88571429 0.64 ENST00000339673.6
ENST00000282479.7
dentin matrix acidic phosphoprotein 1
chr11_+_7110165 0.63 ENST00000306904.5
RNA binding motif protein, X-linked-like 2
chr10_-_75118611 0.63 ENST00000355577.3
ENST00000394865.1
ENST00000310715.3
ENST00000401621.2
tetratricopeptide repeat domain 18
chr6_-_11382478 0.62 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
neural precursor cell expressed, developmentally down-regulated 9
chr11_-_62457371 0.62 ENST00000317449.4
LRRN4 C-terminal like
chr18_+_61445007 0.62 ENST00000447428.1
ENST00000546027.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr15_-_76352069 0.62 ENST00000305435.10
ENST00000563910.1
neuregulin 4
chr2_-_4703793 0.61 ENST00000421212.1
ENST00000412134.1
AC022311.1
chr6_-_49834209 0.61 ENST00000507853.1
cysteine-rich secretory protein 1
chr3_+_184530173 0.61 ENST00000453056.1
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr6_+_21666633 0.60 ENST00000606851.1
cancer susceptibility candidate 15 (non-protein coding)
chrX_-_107975917 0.59 ENST00000563887.1
Uncharacterized protein
chr6_-_169364429 0.59 ENST00000444586.1
RP3-495K2.3
chr6_+_147981838 0.59 ENST00000427015.1
ENST00000432506.1
RP11-307P5.1
chr5_+_140557371 0.58 ENST00000239444.2
protocadherin beta 8
chrX_-_71525742 0.58 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXQ1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.7 2.1 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.5 1.5 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.5 1.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.4 1.3 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.4 1.7 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.4 1.3 GO:1902598 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.4 1.2 GO:0008057 eye pigment granule organization(GO:0008057)
0.3 1.2 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.3 0.9 GO:0061110 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.3 2.0 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 1.7 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.3 0.8 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.3 1.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.2 1.0 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.9 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 0.9 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.2 1.8 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 1.3 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.6 GO:0060279 positive regulation of ovulation(GO:0060279)
0.2 8.8 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.2 3.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 1.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 0.8 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 1.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.2 0.8 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 1.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 2.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2 0.5 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 2.1 GO:0046449 creatinine metabolic process(GO:0046449)
0.2 1.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.2 4.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.2 1.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 1.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.6 GO:1905174 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.6 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 5.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.7 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.5 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.6 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 1.7 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 0.6 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 3.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.8 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.9 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 1.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.8 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.1 0.5 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.4 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.3 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.7 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.5 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 3.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.7 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) membrane depolarization during SA node cell action potential(GO:0086046)
0.1 1.0 GO:0032808 lacrimal gland development(GO:0032808)
0.1 1.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.0 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 9.2 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.7 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.5 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 0.4 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 1.0 GO:0046541 regulation of vascular smooth muscle contraction(GO:0003056) saliva secretion(GO:0046541)
0.1 1.8 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.6 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.1 0.2 GO:0042214 terpene metabolic process(GO:0042214)
0.1 0.7 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.8 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.8 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.4 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 1.0 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 1.3 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 1.0 GO:0015074 DNA integration(GO:0015074)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.1 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.8 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 1.2 GO:0019532 oxalate transport(GO:0019532)
0.1 0.4 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.7 GO:0070836 caveola assembly(GO:0070836)
0.1 0.4 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.7 GO:0015705 iodide transport(GO:0015705)
0.1 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.5 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.7 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.5 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1 0.3 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.2 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.4 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 2.3 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.0 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 3.2 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.8 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.5 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.9 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 2.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.0 1.1 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0044211 CTP salvage(GO:0044211)
0.0 0.2 GO:0009624 response to nematode(GO:0009624) eosinophil differentiation(GO:0030222)
0.0 0.9 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.4 GO:0051451 myoblast migration(GO:0051451)
0.0 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 1.0 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.5 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.5 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.4 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.3 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.7 GO:0007625 grooming behavior(GO:0007625)
0.0 1.0 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.4 GO:0045008 depyrimidination(GO:0045008)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.4 GO:0072189 ureter development(GO:0072189)
0.0 1.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.6 GO:0040008 regulation of growth(GO:0040008)
0.0 3.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.3 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 0.2 GO:1902365 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 1.7 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.0 GO:0033967 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.6 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.3 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.4 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.5 GO:0046688 response to copper ion(GO:0046688)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.9 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.5 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.5 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.3 1.7 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.3 1.5 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 3.2 GO:0036157 outer dynein arm(GO:0036157)
0.2 0.7 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 0.6 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 3.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 6.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 3.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.3 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.0 GO:0033263 CORVET complex(GO:0033263)
0.1 0.3 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 1.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 2.4 GO:0032982 myosin filament(GO:0032982)
0.1 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 11.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.9 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 2.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.8 GO:0036038 MKS complex(GO:0036038)
0.0 1.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.5 GO:0042587 glycogen granule(GO:0042587)
0.0 3.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.8 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 1.8 GO:0031430 M band(GO:0031430)
0.0 1.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0000801 central element(GO:0000801)
0.0 0.6 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.8 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0055028 cortical microtubule(GO:0055028)
0.0 3.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 2.6 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.5 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 2.9 GO:0005903 brush border(GO:0005903)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.7 GO:0031904 endosome lumen(GO:0031904)
0.0 1.9 GO:0005604 basement membrane(GO:0005604)
0.0 1.5 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 1.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0035643 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.4 1.3 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.3 1.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.3 0.9 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.3 1.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.3 1.3 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 0.9 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.2 1.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 10.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 3.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 2.6 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.2 1.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.5 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2 1.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.4 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.6 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.5 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.7 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.9 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 4.1 GO:0000339 RNA cap binding(GO:0000339)
0.1 1.0 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.3 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 2.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.5 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 1.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 2.4 GO:0042166 acetylcholine binding(GO:0042166)
0.1 0.5 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.3 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.1 0.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.4 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 2.4 GO:0031005 filamin binding(GO:0031005)
0.1 2.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0016295 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.1 0.4 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 1.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.5 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.1 0.2 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.7 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 1.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 2.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 2.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 1.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.5 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.4 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.7 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.9 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.2 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 1.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 5.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 1.1 GO:0070330 aromatase activity(GO:0070330)
0.0 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.9 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.8 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 2.8 GO:0070888 E-box binding(GO:0070888)
0.0 5.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 1.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 2.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 4.3 GO:0005178 integrin binding(GO:0005178)
0.0 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 2.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 1.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 2.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 3.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 11.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 3.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.7 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 4.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.1 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 2.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 7.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 5.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.6 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 1.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 2.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 3.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling