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Illumina Body Map 2, young vs old

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Results for FUBP1

Z-value: 0.31

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Transcription factors associated with FUBP1

Gene Symbol Gene ID Gene Info
FUBP1
ENSG00000162613.12 far upstream element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FUBP1hg19_v2_chr1_-_78444776_78444800-0.192.9e-01Click!

Activity profile of FUBP1 motif

Sorted Z-values of FUBP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_10421853 6.16 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr11_-_107590383 5.11 ENST00000525934.1
ENST00000531293.1
SLN
sarcolipin
chr1_+_145413268 4.50 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
HFE2
hemochromatosis type 2 (juvenile)
chrX_-_55020511 4.47 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr1_-_115238207 3.67 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
AMPD1
adenosine monophosphate deaminase 1
chr12_+_54366894 3.32 ENST00000546378.1
ENST00000243082.4
HOXC11
homeobox C11
chr3_-_187454281 3.08 ENST00000232014.4
BCL6
B-cell CLL/lymphoma 6
chr3_-_196242233 3.05 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr1_-_27701307 2.99 ENST00000270879.4
ENST00000354982.2
FCN3
ficolin (collagen/fibrinogen domain containing) 3
chr11_-_10590118 2.88 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr7_+_116166331 2.70 ENST00000393468.1
ENST00000393467.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr4_-_44653636 2.67 ENST00000415895.4
ENST00000332990.5
YIPF7
Yip1 domain family, member 7
chr11_-_10590238 2.66 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr17_-_41739283 2.63 ENST00000393661.2
ENST00000318579.4
MEOX1
mesenchyme homeobox 1
chr19_-_45996465 2.62 ENST00000430715.2
RTN2
reticulon 2
chr12_+_48513570 2.62 ENST00000551804.1
PFKM
phosphofructokinase, muscle
chr4_-_100242549 2.62 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr17_-_41738931 2.58 ENST00000329168.3
ENST00000549132.1
MEOX1
mesenchyme homeobox 1
chr15_-_56209306 2.52 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr11_+_113930955 2.48 ENST00000535700.1
ZBTB16
zinc finger and BTB domain containing 16
chr1_+_10290822 2.45 ENST00000377083.1
KIF1B
kinesin family member 1B
chr14_+_61654271 2.43 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr1_+_78383813 2.40 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr12_+_111374375 2.25 ENST00000553177.1
ENST00000548368.1
ENST00000331096.2
ENST00000547607.1
RP1-46F2.2
RP1-46F2.2
chr17_+_67498538 2.20 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr9_-_110251836 2.17 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr11_+_111473108 2.05 ENST00000304987.3
SIK2
salt-inducible kinase 2
chr17_+_67498295 2.00 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr1_+_202317855 1.97 ENST00000356764.2
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chrX_-_33146477 1.84 ENST00000378677.2
DMD
dystrophin
chr12_+_57522692 1.84 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr11_+_110001723 1.77 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr1_+_31886653 1.74 ENST00000536384.1
SERINC2
serine incorporator 2
chr5_-_1882858 1.73 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr1_-_182360498 1.69 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chr3_-_47950745 1.69 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr9_+_135457530 1.68 ENST00000263610.2
BARHL1
BarH-like homeobox 1
chr1_-_182360918 1.64 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chr16_+_28565230 1.60 ENST00000317058.3
CCDC101
coiled-coil domain containing 101
chr21_+_30502806 1.59 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr19_+_41094612 1.57 ENST00000595726.1
SHKBP1
SH3KBP1 binding protein 1
chr5_+_36608280 1.57 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_40041925 1.54 ENST00000372862.3
PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr11_+_60681346 1.52 ENST00000227525.3
TMEM109
transmembrane protein 109
chr4_-_16900242 1.52 ENST00000502640.1
ENST00000506732.1
LDB2
LIM domain binding 2
chr5_+_54320078 1.51 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chrX_+_95939638 1.51 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2
diaphanous-related formin 2
chr2_+_27435734 1.50 ENST00000419744.1
ATRAID
all-trans retinoic acid-induced differentiation factor
chr18_-_53255379 1.49 ENST00000565908.2
TCF4
transcription factor 4
chr6_-_111888474 1.46 ENST00000368735.1
TRAF3IP2
TRAF3 interacting protein 2
chr12_-_22094336 1.46 ENST00000326684.4
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr17_-_74049720 1.42 ENST00000602720.1
SRP68
signal recognition particle 68kDa
chr10_+_79793518 1.41 ENST00000440692.1
ENST00000435275.1
ENST00000372360.3
ENST00000360830.4
RPS24
ribosomal protein S24
chr2_+_162087577 1.41 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr6_-_31612808 1.41 ENST00000438149.1
BAG6
BCL2-associated athanogene 6
chr5_-_88179017 1.41 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
MEF2C
myocyte enhancer factor 2C
chr12_-_91576429 1.38 ENST00000552145.1
ENST00000546745.1
DCN
decorin
chr1_+_43766668 1.38 ENST00000441333.2
ENST00000538015.1
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr5_-_88178964 1.38 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
MEF2C
myocyte enhancer factor 2C
chr11_-_47521309 1.37 ENST00000535982.1
CELF1
CUGBP, Elav-like family member 1
chr19_+_10765614 1.35 ENST00000589283.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr4_-_101439148 1.34 ENST00000511970.1
ENST00000502569.1
ENST00000305864.3
EMCN
endomucin
chr4_-_16900217 1.32 ENST00000441778.2
LDB2
LIM domain binding 2
chr19_+_13134772 1.31 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr12_-_22094159 1.29 ENST00000538350.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr6_-_56507586 1.29 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
DST
dystonin
chr1_+_202317815 1.29 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr18_-_53255766 1.29 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr4_-_152149033 1.26 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr4_-_16900410 1.25 ENST00000304523.5
LDB2
LIM domain binding 2
chr12_+_54384370 1.25 ENST00000504315.1
HOXC6
homeobox C6
chr1_+_43766642 1.24 ENST00000372476.3
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr12_-_91576561 1.24 ENST00000547568.2
ENST00000552962.1
DCN
decorin
chrX_-_65259914 1.20 ENST00000374737.4
ENST00000455586.2
VSIG4
V-set and immunoglobulin domain containing 4
chr18_+_7754957 1.20 ENST00000400053.4
PTPRM
protein tyrosine phosphatase, receptor type, M
chrX_-_65259900 1.17 ENST00000412866.2
VSIG4
V-set and immunoglobulin domain containing 4
chr4_-_16900184 1.17 ENST00000515064.1
LDB2
LIM domain binding 2
chr19_+_1438351 1.15 ENST00000233609.4
RPS15
ribosomal protein S15
chr17_+_67498396 1.15 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr5_+_145316120 1.13 ENST00000359120.4
SH3RF2
SH3 domain containing ring finger 2
chr6_+_37897735 1.12 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr12_-_46766577 1.10 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr17_+_79953310 1.09 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr6_-_31613280 1.09 ENST00000453833.1
BAG6
BCL2-associated athanogene 6
chr3_+_148545586 1.09 ENST00000282957.4
ENST00000468341.1
CPB1
carboxypeptidase B1 (tissue)
chr12_+_16109519 1.08 ENST00000526530.1
DERA
deoxyribose-phosphate aldolase (putative)
chr10_-_32667660 1.03 ENST00000375110.2
EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr17_-_42298201 1.03 ENST00000527034.1
UBTF
upstream binding transcription factor, RNA polymerase I
chr12_+_57522258 1.02 ENST00000553277.1
ENST00000243077.3
LRP1
low density lipoprotein receptor-related protein 1
chrX_+_12924732 1.02 ENST00000218032.6
ENST00000311912.5
TLR8
toll-like receptor 8
chr5_+_156607829 1.02 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr12_+_57522439 1.01 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chr10_+_17686193 1.00 ENST00000377500.1
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr21_-_38445011 0.98 ENST00000464265.1
ENST00000399102.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chrX_+_95939711 0.95 ENST00000373049.4
ENST00000324765.8
DIAPH2
diaphanous-related formin 2
chr10_-_105845536 0.94 ENST00000393211.3
COL17A1
collagen, type XVII, alpha 1
chr4_-_101439242 0.93 ENST00000296420.4
EMCN
endomucin
chr2_+_201980827 0.91 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
CFLAR
CASP8 and FADD-like apoptosis regulator
chr7_-_22234381 0.91 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr4_-_186578674 0.89 ENST00000438278.1
SORBS2
sorbin and SH3 domain containing 2
chr3_+_130279178 0.87 ENST00000358511.6
ENST00000453409.2
COL6A6
collagen, type VI, alpha 6
chr4_-_84205905 0.87 ENST00000311461.7
ENST00000311469.4
ENST00000439031.2
COQ2
coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
chr7_+_139528952 0.86 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr18_-_60986613 0.86 ENST00000444484.1
BCL2
B-cell CLL/lymphoma 2
chr12_+_14572070 0.86 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr14_+_76072096 0.84 ENST00000555058.1
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr3_+_133524459 0.84 ENST00000484684.1
SRPRB
signal recognition particle receptor, B subunit
chr9_+_75766763 0.84 ENST00000456643.1
ENST00000415424.1
ANXA1
annexin A1
chr2_-_72374948 0.83 ENST00000546307.1
ENST00000474509.1
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr12_-_91451758 0.83 ENST00000266719.3
KERA
keratocan
chr17_-_76713100 0.81 ENST00000585509.1
CYTH1
cytohesin 1
chr15_-_55657428 0.81 ENST00000568543.1
CCPG1
cell cycle progression 1
chr1_-_11741155 0.81 ENST00000445656.1
ENST00000376669.5
ENST00000456915.1
ENST00000376692.4
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr7_-_75401513 0.80 ENST00000005180.4
CCL26
chemokine (C-C motif) ligand 26
chr7_-_22233442 0.78 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr21_+_45209394 0.76 ENST00000497547.1
RRP1
ribosomal RNA processing 1
chr19_+_10751715 0.76 ENST00000430975.1
AC011475.1
Uncharacterized protein
chr22_-_50970919 0.75 ENST00000329363.4
ENST00000437588.1
ODF3B
outer dense fiber of sperm tails 3B
chr3_-_71114066 0.75 ENST00000485326.2
FOXP1
forkhead box P1
chr16_-_69419473 0.74 ENST00000566750.1
TERF2
telomeric repeat binding factor 2
chr2_-_72375167 0.74 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr11_-_33891362 0.73 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr18_-_60985914 0.71 ENST00000589955.1
BCL2
B-cell CLL/lymphoma 2
chr20_-_45981138 0.71 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr7_-_74267836 0.71 ENST00000361071.5
ENST00000453619.2
ENST00000417115.2
ENST00000405086.2
GTF2IRD2
GTF2I repeat domain containing 2
chr10_+_17686221 0.70 ENST00000540523.1
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr5_+_173316341 0.67 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr7_+_129710350 0.66 ENST00000335420.5
ENST00000463413.1
KLHDC10
kelch domain containing 10
chr11_-_46142505 0.66 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr6_+_34725263 0.66 ENST00000374018.1
ENST00000374017.3
SNRPC
small nuclear ribonucleoprotein polypeptide C
chr6_+_121756809 0.65 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr19_+_18682661 0.64 ENST00000596273.1
ENST00000442744.2
ENST00000595683.1
ENST00000599256.1
ENST00000595158.1
ENST00000598780.1
UBA52
ubiquitin A-52 residue ribosomal protein fusion product 1
chr22_-_50970566 0.64 ENST00000405135.1
ENST00000401779.1
ODF3B
outer dense fiber of sperm tails 3B
chr12_+_10365082 0.63 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr7_+_139529040 0.63 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr6_-_31509506 0.59 ENST00000449757.1
DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr1_+_41157361 0.59 ENST00000427410.2
ENST00000447388.3
ENST00000425457.2
ENST00000453631.1
ENST00000456393.2
NFYC
nuclear transcription factor Y, gamma
chr3_-_71632894 0.58 ENST00000493089.1
FOXP1
forkhead box P1
chr1_-_157670647 0.56 ENST00000368184.3
FCRL3
Fc receptor-like 3
chr19_+_11546093 0.55 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr7_-_127032114 0.55 ENST00000436992.1
ZNF800
zinc finger protein 800
chr2_-_208030295 0.55 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr2_-_175202151 0.55 ENST00000595354.1
AC018470.1
Uncharacterized protein FLJ46347
chr17_+_75369400 0.54 ENST00000590059.1
SEPT9
septin 9
chr2_-_152118276 0.54 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr17_-_77005813 0.53 ENST00000590370.1
ENST00000591625.1
CANT1
calcium activated nucleotidase 1
chr11_+_57531292 0.52 ENST00000524579.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr9_+_96846740 0.52 ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr4_-_140544386 0.52 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr8_-_101719159 0.52 ENST00000520868.1
ENST00000522658.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr2_+_113033164 0.52 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr12_+_57810198 0.51 ENST00000598001.1
AC126614.1
HCG1818482; Uncharacterized protein
chrX_-_73513353 0.51 ENST00000430772.1
ENST00000423992.2
ENST00000602812.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr2_-_27435390 0.51 ENST00000428518.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr11_+_64004888 0.50 ENST00000541681.1
VEGFB
vascular endothelial growth factor B
chr15_+_52155001 0.50 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chr21_-_38445297 0.50 ENST00000430792.1
ENST00000399103.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr3_-_149051444 0.49 ENST00000296059.2
TM4SF18
transmembrane 4 L six family member 18
chr11_+_120207787 0.48 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr22_-_50970506 0.48 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chrX_-_19533379 0.47 ENST00000338883.4
MAP3K15
mitogen-activated protein kinase kinase kinase 15
chr4_+_89444961 0.47 ENST00000513325.1
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr10_+_98592674 0.46 ENST00000356016.3
ENST00000371097.4
LCOR
ligand dependent nuclear receptor corepressor
chr1_-_157670528 0.46 ENST00000368186.5
ENST00000496769.1
FCRL3
Fc receptor-like 3
chr1_-_150738261 0.45 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr1_+_198608292 0.43 ENST00000418674.1
PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_+_33359473 0.42 ENST00000432635.1
LTBP1
latent transforming growth factor beta binding protein 1
chr19_+_48969094 0.42 ENST00000595676.1
CTC-273B12.7
Uncharacterized protein
chr2_-_65593784 0.42 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr7_+_74508372 0.41 ENST00000356115.5
ENST00000430511.2
ENST00000312575.7
GTF2IRD2B
GTF2I repeat domain containing 2B
chr10_+_17686124 0.41 ENST00000377524.3
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr1_+_89149905 0.41 ENST00000316005.7
ENST00000370521.3
ENST00000370505.3
PKN2
protein kinase N2
chr11_-_46142615 0.41 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr2_+_177015950 0.40 ENST00000306324.3
HOXD4
homeobox D4
chr6_+_125524785 0.40 ENST00000392482.2
TPD52L1
tumor protein D52-like 1
chr10_+_51187938 0.40 ENST00000311663.5
FAM21D
family with sequence similarity 21, member D
chr15_-_34628951 0.40 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr1_-_45140227 0.39 ENST00000372237.3
TMEM53
transmembrane protein 53
chr13_-_26795840 0.38 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
RNF6
ring finger protein (C3H2C3 type) 6
chr7_-_83824449 0.37 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr4_-_2420335 0.37 ENST00000503000.1
ZFYVE28
zinc finger, FYVE domain containing 28
chr10_+_114710516 0.37 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr15_-_31521567 0.35 ENST00000560812.1
ENST00000559853.1
ENST00000558109.1
RP11-16E12.2
RP11-16E12.2
chr10_-_91102410 0.35 ENST00000282673.4
LIPA
lipase A, lysosomal acid, cholesterol esterase
chr12_-_57522813 0.35 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr14_-_23762777 0.35 ENST00000431326.2
HOMEZ
homeobox and leucine zipper encoding
chr12_+_10365404 0.35 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chrX_+_119737806 0.34 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr1_+_171107241 0.34 ENST00000236166.3
FMO6P
flavin containing monooxygenase 6 pseudogene
chr17_-_77005801 0.32 ENST00000392446.5
CANT1
calcium activated nucleotidase 1
chr12_+_12870055 0.32 ENST00000228872.4
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr5_-_34919094 0.32 ENST00000341754.4
RAD1
RAD1 homolog (S. pombe)
chr3_+_48488497 0.32 ENST00000412052.1
ATRIP
ATR interacting protein
chr11_-_67169253 0.31 ENST00000527663.1
ENST00000312989.7
PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr19_+_19303008 0.31 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr17_-_8151353 0.31 ENST00000315684.8
CTC1
CTS telomere maintenance complex component 1
chr10_-_65028817 0.30 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr1_-_44818599 0.30 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr19_+_36235964 0.30 ENST00000587708.2
PSENEN
presenilin enhancer gamma secretase subunit
chr2_-_228497888 0.30 ENST00000264387.4
ENST00000409066.1
C2orf83
chromosome 2 open reading frame 83

Network of associatons between targets according to the STRING database.

First level regulatory network of FUBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
1.1 5.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.9 2.7 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.9 5.2 GO:0061056 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.8 3.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.8 3.9 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.8 3.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.6 4.5 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.6 2.4 GO:1904647 response to rotenone(GO:1904647)
0.5 2.2 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.5 1.6 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.4 2.6 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.4 2.5 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.4 2.8 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.4 1.6 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.4 2.5 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.3 3.8 GO:0032264 IMP salvage(GO:0032264)
0.3 3.0 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.3 1.7 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.3 0.8 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.3 1.0 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.2 2.5 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.2 2.4 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.2 1.7 GO:0051012 microtubule sliding(GO:0051012)
0.2 2.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.2 1.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 4.5 GO:0016540 protein autoprocessing(GO:0016540)
0.2 0.7 GO:1903823 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.2 1.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.2 1.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 5.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 0.7 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 3.3 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 1.6 GO:0070777 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 1.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.8 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.5 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 2.6 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 0.6 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.1 2.6 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.7 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.1 0.8 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 1.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 2.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 4.0 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 1.0 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.3 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 0.4 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 1.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.1 0.4 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 1.1 GO:0032328 alanine transport(GO:0032328)
0.1 0.5 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.4 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.3 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.1 0.7 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 1.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.9 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 1.5 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 0.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.4 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 1.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.3 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.2 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 1.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.0 0.8 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 1.5 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.7 GO:0061051 viral mRNA export from host cell nucleus(GO:0046784) positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.5 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 1.4 GO:0016246 RNA interference(GO:0016246)
0.0 0.2 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 1.0 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 2.6 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 1.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 2.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.9 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.8 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.3 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 1.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 1.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.0 GO:0043968 vascular smooth muscle cell differentiation(GO:0035886) histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.0 0.3 GO:1902746 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 1.2 GO:0010842 retina layer formation(GO:0010842)
0.0 1.6 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 0.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.9 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 2.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 2.6 GO:0065002 intracellular protein transmembrane transport(GO:0065002)
0.0 2.5 GO:0048477 oogenesis(GO:0048477)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 1.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 1.1 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 1.1 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.3 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 6.5 GO:0006936 muscle contraction(GO:0006936)
0.0 1.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 1.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 2.6 GO:0014802 terminal cisterna(GO:0014802)
0.3 2.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.3 2.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.3 4.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 1.6 GO:0031673 H zone(GO:0031673)
0.2 2.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 6.2 GO:0032982 myosin filament(GO:0032982)
0.2 2.6 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 2.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 1.8 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.4 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.8 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 3.3 GO:0097386 glial cell projection(GO:0097386)
0.1 1.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 5.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.5 GO:0036021 endolysosome lumen(GO:0036021)
0.1 1.0 GO:0070187 telosome(GO:0070187)
0.1 0.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.7 GO:0005688 U6 snRNP(GO:0005688)
0.1 2.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.7 GO:0000243 commitment complex(GO:0000243)
0.0 2.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 1.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 3.3 GO:0031672 A band(GO:0031672)
0.0 1.0 GO:0036020 endolysosome membrane(GO:0036020)
0.0 1.1 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 2.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 4.4 GO:0005581 collagen trimer(GO:0005581)
0.0 3.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.1 GO:0005657 replication fork(GO:0005657)
0.0 0.9 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0072357 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.1 GO:1990391 DNA repair complex(GO:1990391)
0.0 3.3 GO:0030018 Z disc(GO:0030018)
0.0 10.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 5.0 GO:0044445 cytosolic part(GO:0044445)
0.0 2.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.5 GO:0031105 septin complex(GO:0031105)
0.0 1.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.7 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.0 GO:0005903 brush border(GO:0005903)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.9 2.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.9 4.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.8 3.3 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.7 2.8 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.6 4.5 GO:0098821 BMP receptor activity(GO:0098821)
0.5 1.5 GO:0017130 poly(C) RNA binding(GO:0017130)
0.4 5.3 GO:0030274 LIM domain binding(GO:0030274)
0.4 3.8 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4 1.5 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.4 2.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.4 1.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.3 2.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.3 2.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.3 2.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.3 2.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.3 2.6 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 8.0 GO:0071837 HMG box domain binding(GO:0071837)
0.2 1.6 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 1.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 0.7 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.2 0.9 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.2 1.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 0.8 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.2 1.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 1.4 GO:0042835 BRE binding(GO:0042835)
0.1 1.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 2.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.6 GO:0051434 BH3 domain binding(GO:0051434)
0.1 5.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 5.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 2.5 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.7 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 2.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 1.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.7 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.7 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 1.8 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.3 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.7 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 1.0 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 1.0 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 2.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.4 GO:0019894 kinesin binding(GO:0019894)
0.0 5.1 GO:0051117 ATPase binding(GO:0051117)
0.0 3.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 3.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.5 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 4.0 GO:0003774 motor activity(GO:0003774)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.8 GO:0020037 heme binding(GO:0020037)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 2.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 2.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 3.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 4.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 6.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 4.8 PID BMP PATHWAY BMP receptor signaling
0.0 2.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 3.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 4.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 6.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 2.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 0.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 2.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 3.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 5.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 3.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 6.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 2.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 2.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 2.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 4.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 2.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 2.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 3.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.7 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 2.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 1.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 1.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 2.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 5.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases