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Illumina Body Map 2, young vs old

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Results for GAGGUAG

Z-value: 0.40

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miRNA associated with seed GAGGUAG

NamemiRBASE accession
hsa-let-7a-5p
MIMAT0000062
hsa-let-7b-5p
MIMAT0000063
hsa-let-7c-5p
MIMAT0000064
hsa-let-7d-5p
MIMAT0000065
hsa-let-7e-5p
MIMAT0000066
hsa-let-7f-5p
MIMAT0000067
hsa-let-7g-5p
MIMAT0000414
hsa-let-7i-5p
MIMAT0000415
hsa-miR-98-5p
MIMAT0000096
hsa-miR-4458
MIMAT0018980
hsa-miR-4500
MIMAT0019036

Activity profile of GAGGUAG motif

Sorted Z-values of GAGGUAG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_77774897 2.72 ENST00000281030.2
THRSP
thyroid hormone responsive
chr2_+_189839046 2.38 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr17_-_48278983 2.30 ENST00000225964.5
COL1A1
collagen, type I, alpha 1
chr5_+_42423872 2.08 ENST00000230882.4
ENST00000357703.3
GHR
growth hormone receptor
chr11_+_130318869 1.86 ENST00000299164.2
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr7_+_94023873 1.79 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chr21_-_28338732 1.77 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr2_-_1748214 1.69 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN
peroxidasin homolog (Drosophila)
chr15_-_51630772 1.64 ENST00000557858.1
ENST00000558328.1
ENST00000396404.4
ENST00000561075.1
ENST00000405011.2
ENST00000559980.1
ENST00000453807.2
ENST00000396402.1
CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr17_+_8213590 1.63 ENST00000361926.3
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr9_-_129885010 1.52 ENST00000373425.3
ANGPTL2
angiopoietin-like 2
chrX_+_2746850 1.46 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
GYG2
glycogenin 2
chrX_+_105066524 1.45 ENST00000243300.9
ENST00000428173.2
NRK
Nik related kinase
chr7_-_132261253 1.42 ENST00000321063.4
PLXNA4
plexin A4
chr4_-_174451370 1.30 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr9_+_101705893 1.25 ENST00000375001.3
COL15A1
collagen, type XV, alpha 1
chr11_-_86666427 1.25 ENST00000531380.1
FZD4
frizzled family receptor 4
chr13_+_110959598 1.23 ENST00000360467.5
COL4A2
collagen, type IV, alpha 2
chr14_+_24867992 1.22 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr11_-_10590238 1.16 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr12_-_102874416 1.11 ENST00000392904.1
ENST00000337514.6
IGF1
insulin-like growth factor 1 (somatomedin C)
chr17_+_34058639 1.09 ENST00000268864.3
RASL10B
RAS-like, family 10, member B
chr6_-_53530474 1.08 ENST00000370905.3
KLHL31
kelch-like family member 31
chr2_-_190044480 1.08 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr14_-_52535712 1.02 ENST00000216286.5
ENST00000541773.1
NID2
nidogen 2 (osteonidogen)
chr11_-_27494279 0.95 ENST00000379214.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr1_-_115880852 0.94 ENST00000369512.2
NGF
nerve growth factor (beta polypeptide)
chr17_+_8924837 0.94 ENST00000173229.2
NTN1
netrin 1
chr9_+_19408999 0.92 ENST00000340967.2
ACER2
alkaline ceramidase 2
chr8_-_37824442 0.91 ENST00000345060.3
ADRB3
adrenoceptor beta 3
chr6_-_31107127 0.90 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr3_-_127542021 0.89 ENST00000434178.2
MGLL
monoglyceride lipase
chr15_+_74466012 0.89 ENST00000249842.3
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr1_-_92351769 0.88 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr1_+_170632250 0.88 ENST00000367760.3
PRRX1
paired related homeobox 1
chr9_+_116917807 0.86 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr19_-_7293942 0.85 ENST00000341500.5
ENST00000302850.5
INSR
insulin receptor
chr12_-_69326940 0.85 ENST00000549781.1
ENST00000548262.1
ENST00000551568.1
ENST00000548954.1
CPM
carboxypeptidase M
chr1_-_156051789 0.83 ENST00000532414.2
MEX3A
mex-3 RNA binding family member A
chr22_+_24115000 0.83 ENST00000215743.3
MMP11
matrix metallopeptidase 11 (stromelysin 3)
chr9_-_16870704 0.83 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr3_+_16216137 0.81 ENST00000339732.5
GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr3_-_87040233 0.81 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr12_-_59313270 0.80 ENST00000379141.4
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr8_+_74206829 0.79 ENST00000240285.5
RDH10
retinol dehydrogenase 10 (all-trans)
chr5_+_38846101 0.78 ENST00000274276.3
OSMR
oncostatin M receptor
chr15_-_50411412 0.78 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr6_-_35464727 0.78 ENST00000402886.3
TEAD3
TEA domain family member 3
chr17_+_1958388 0.77 ENST00000399849.3
HIC1
hypermethylated in cancer 1
chr12_+_103981044 0.72 ENST00000388887.2
STAB2
stabilin 2
chr8_-_122653630 0.72 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr21_-_28217721 0.69 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr5_+_150157444 0.69 ENST00000526627.1
SMIM3
small integral membrane protein 3
chr3_+_49209023 0.69 ENST00000332780.2
KLHDC8B
kelch domain containing 8B
chr15_-_37390482 0.69 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr7_+_3340989 0.68 ENST00000404826.2
ENST00000389531.3
SDK1
sidekick cell adhesion molecule 1
chr5_+_172261228 0.67 ENST00000393784.3
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr2_-_158485387 0.67 ENST00000243349.8
ACVR1C
activin A receptor, type IC
chr18_+_6834472 0.67 ENST00000581099.1
ENST00000419673.2
ENST00000531294.1
ARHGAP28
Rho GTPase activating protein 28
chr3_+_39851094 0.65 ENST00000302541.6
MYRIP
myosin VIIA and Rab interacting protein
chr7_-_27205136 0.65 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr2_-_161350305 0.64 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chrX_+_56259316 0.64 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr1_+_153232160 0.64 ENST00000368742.3
LOR
loricrin
chr2_-_27435125 0.64 ENST00000414408.1
ENST00000310574.3
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr16_+_447209 0.63 ENST00000382940.4
ENST00000219479.2
NME4
NME/NM23 nucleoside diphosphate kinase 4
chr17_-_42908155 0.63 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1
gap junction protein, gamma 1, 45kDa
chr5_-_41510656 0.63 ENST00000377801.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr16_-_11350036 0.62 ENST00000332029.2
SOCS1
suppressor of cytokine signaling 1
chr16_+_22217577 0.61 ENST00000263026.5
EEF2K
eukaryotic elongation factor-2 kinase
chr12_+_50690489 0.61 ENST00000598429.1
AC140061.12
Uncharacterized protein
chr20_-_46415297 0.60 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chrX_+_49687216 0.59 ENST00000376088.3
CLCN5
chloride channel, voltage-sensitive 5
chr6_+_41606176 0.59 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MDFI
MyoD family inhibitor
chr7_-_138720763 0.59 ENST00000275766.1
ZC3HAV1L
zinc finger CCCH-type, antiviral 1-like
chrX_-_107681633 0.58 ENST00000394872.2
ENST00000334504.7
COL4A6
collagen, type IV, alpha 6
chr13_-_110959478 0.58 ENST00000543140.1
ENST00000375820.4
COL4A1
collagen, type IV, alpha 1
chr7_+_120628731 0.57 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr10_+_73724123 0.57 ENST00000373115.4
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr1_-_204121013 0.57 ENST00000367201.3
ETNK2
ethanolamine kinase 2
chr3_-_79068594 0.56 ENST00000436010.2
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr9_+_109625378 0.56 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462
zinc finger protein 462
chr15_+_39873268 0.56 ENST00000397591.2
ENST00000260356.5
THBS1
thrombospondin 1
chr3_-_49459878 0.56 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT
aminomethyltransferase
chr5_+_150157860 0.56 ENST00000600109.1
AC010441.1
AC010441.1
chr2_-_230933709 0.55 ENST00000436869.1
ENST00000295190.4
SLC16A14
solute carrier family 16, member 14
chr10_+_101419187 0.55 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr3_+_194406603 0.54 ENST00000329759.4
FAM43A
family with sequence similarity 43, member A
chr12_-_65146636 0.54 ENST00000418919.2
GNS
glucosamine (N-acetyl)-6-sulfatase
chr1_+_203595903 0.54 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr13_-_30881621 0.54 ENST00000380615.3
KATNAL1
katanin p60 subunit A-like 1
chr12_+_1800179 0.53 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr11_+_36589547 0.53 ENST00000299440.5
RAG1
recombination activating gene 1
chr7_-_106301405 0.50 ENST00000523505.1
CCDC71L
coiled-coil domain containing 71-like
chr1_-_28503693 0.49 ENST00000373857.3
PTAFR
platelet-activating factor receptor
chr1_+_230202936 0.49 ENST00000366672.4
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr7_+_90032667 0.49 ENST00000496677.1
ENST00000287916.4
ENST00000535571.1
ENST00000394604.1
ENST00000394605.2
CLDN12
claudin 12
chr8_+_70378852 0.48 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1
sulfatase 1
chr2_-_164592497 0.47 ENST00000333129.3
ENST00000409634.1
FIGN
fidgetin
chr6_-_32157947 0.46 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr5_+_65440032 0.46 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr1_-_206945830 0.45 ENST00000423557.1
IL10
interleukin 10
chr5_-_32313019 0.44 ENST00000280285.5
ENST00000264934.5
MTMR12
myotubularin related protein 12
chr1_+_32645269 0.44 ENST00000373610.3
TXLNA
taxilin alpha
chrX_-_33146477 0.44 ENST00000378677.2
DMD
dystrophin
chr3_-_101039402 0.44 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chr15_-_83474806 0.43 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr4_-_87770416 0.43 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr3_+_184097836 0.43 ENST00000204604.1
ENST00000310236.3
CHRD
chordin
chr9_+_118916082 0.43 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr13_+_39612442 0.43 ENST00000470258.1
ENST00000379600.3
NHLRC3
NHL repeat containing 3
chrX_+_16804544 0.42 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr2_+_11674213 0.42 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chr12_+_56511943 0.42 ENST00000257940.2
ENST00000552345.1
ENST00000551880.1
ENST00000546903.1
ENST00000551790.1
ZC3H10
ESYT1
zinc finger CCCH-type containing 10
extended synaptotagmin-like protein 1
chr13_-_33859819 0.41 ENST00000336934.5
STARD13
StAR-related lipid transfer (START) domain containing 13
chr13_+_98794810 0.41 ENST00000595437.1
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr16_-_20911641 0.40 ENST00000564349.1
ENST00000324344.4
ERI2
DCUN1D3
ERI1 exoribonuclease family member 2
DCN1, defective in cullin neddylation 1, domain containing 3
chr18_+_18943554 0.40 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr12_+_56862301 0.40 ENST00000338146.5
SPRYD4
SPRY domain containing 4
chrX_-_117250740 0.40 ENST00000371882.1
ENST00000540167.1
ENST00000545703.1
KLHL13
kelch-like family member 13
chr8_+_121137333 0.40 ENST00000309791.4
ENST00000297848.3
ENST00000247781.3
COL14A1
collagen, type XIV, alpha 1
chr1_-_177939041 0.40 ENST00000308284.6
SEC16B
SEC16 homolog B (S. cerevisiae)
chr8_-_13372395 0.39 ENST00000276297.4
ENST00000511869.1
DLC1
deleted in liver cancer 1
chr6_+_143929307 0.39 ENST00000427704.2
ENST00000305766.6
PHACTR2
phosphatase and actin regulator 2
chr11_+_69455855 0.39 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr2_+_12857015 0.39 ENST00000155926.4
TRIB2
tribbles pseudokinase 2
chr6_+_125283566 0.38 ENST00000521654.2
RNF217
ring finger protein 217
chr1_-_9189229 0.38 ENST00000377411.4
GPR157
G protein-coupled receptor 157
chr4_+_56815102 0.38 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr4_+_159690218 0.38 ENST00000264433.6
FNIP2
folliculin interacting protein 2
chr15_+_36887069 0.38 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr1_+_29563011 0.37 ENST00000345512.3
ENST00000373779.3
ENST00000356870.3
ENST00000323874.8
ENST00000428026.2
ENST00000460170.2
PTPRU
protein tyrosine phosphatase, receptor type, U
chr2_+_128848881 0.37 ENST00000259253.6
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr3_+_89156674 0.37 ENST00000336596.2
EPHA3
EPH receptor A3
chr1_-_108742957 0.37 ENST00000565488.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr19_+_46800289 0.37 ENST00000377670.4
HIF3A
hypoxia inducible factor 3, alpha subunit
chr12_+_56915713 0.37 ENST00000262031.5
ENST00000552247.2
RBMS2
RNA binding motif, single stranded interacting protein 2
chr2_+_128458514 0.36 ENST00000310981.4
SFT2D3
SFT2 domain containing 3
chr2_+_99953816 0.36 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr1_+_12227035 0.36 ENST00000376259.3
ENST00000536782.1
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr14_+_45366472 0.36 ENST00000325192.3
C14orf28
chromosome 14 open reading frame 28
chr14_+_53196872 0.36 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr1_-_47134101 0.36 ENST00000576409.1
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr3_-_129325660 0.36 ENST00000324093.4
ENST00000393239.1
PLXND1
plexin D1
chr10_-_63213177 0.36 ENST00000399298.3
ENST00000399293.1
TMEM26
transmembrane protein 26
chr8_-_93115445 0.36 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_231297798 0.35 ENST00000444294.3
TRIM67
tripartite motif containing 67
chr4_+_95129061 0.35 ENST00000354268.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr12_+_54366894 0.35 ENST00000546378.1
ENST00000243082.4
HOXC11
homeobox C11
chr7_-_27219632 0.35 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chrX_-_129244655 0.35 ENST00000335997.7
ELF4
E74-like factor 4 (ets domain transcription factor)
chr12_+_122516626 0.35 ENST00000319080.7
MLXIP
MLX interacting protein
chr14_+_55518349 0.34 ENST00000395468.4
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr22_-_24093267 0.34 ENST00000341976.3
ZNF70
zinc finger protein 70
chr6_-_8064567 0.34 ENST00000543936.1
ENST00000397457.2
BLOC1S5
biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr2_+_119981384 0.34 ENST00000393108.2
ENST00000354888.5
ENST00000450943.2
ENST00000393110.2
ENST00000393106.2
ENST00000409811.1
ENST00000393107.2
STEAP3
STEAP family member 3, metalloreductase
chr5_-_131563501 0.34 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr11_+_32112431 0.34 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr17_-_38721711 0.34 ENST00000578085.1
ENST00000246657.2
CCR7
chemokine (C-C motif) receptor 7
chr5_-_146833485 0.33 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr3_-_33138286 0.33 ENST00000416695.2
ENST00000342462.4
ENST00000399402.3
TMPPE
GLB1
transmembrane protein with metallophosphoesterase domain
galactosidase, beta 1
chr13_-_95248511 0.33 ENST00000261296.5
TGDS
TDP-glucose 4,6-dehydratase
chr12_-_56652111 0.33 ENST00000267116.7
ANKRD52
ankyrin repeat domain 52
chr21_+_42539701 0.33 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
BACE2
beta-site APP-cleaving enzyme 2
chr22_-_36236265 0.32 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_-_71221942 0.32 ENST00000272438.4
TEX261
testis expressed 261
chr18_-_30050395 0.32 ENST00000269209.6
ENST00000399218.4
GAREM
GRB2 associated, regulator of MAPK1
chr17_+_41476327 0.32 ENST00000320033.4
ARL4D
ADP-ribosylation factor-like 4D
chr11_+_86748863 0.32 ENST00000340353.7
TMEM135
transmembrane protein 135
chr3_-_183273477 0.32 ENST00000341319.3
KLHL6
kelch-like family member 6
chr22_+_18043133 0.31 ENST00000327451.6
ENST00000399813.1
SLC25A18
solute carrier family 25 (glutamate carrier), member 18
chr21_+_45079409 0.31 ENST00000340648.4
RRP1B
ribosomal RNA processing 1B
chr10_+_102106829 0.31 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr8_+_126442563 0.31 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr1_+_101361626 0.31 ENST00000370112.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr18_+_21693306 0.31 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr1_+_164528866 0.31 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr5_+_148206156 0.31 ENST00000305988.4
ADRB2
adrenoceptor beta 2, surface
chr1_-_6295975 0.31 ENST00000343813.5
ENST00000362035.3
ICMT
isoprenylcysteine carboxyl methyltransferase
chr1_+_161129254 0.31 ENST00000368002.3
ENST00000289865.8
ENST00000479344.1
ENST00000368001.1
USP21
ubiquitin specific peptidase 21
chr5_+_129240151 0.30 ENST00000305031.4
CHSY3
chondroitin sulfate synthase 3
chr14_+_55493920 0.30 ENST00000395472.2
ENST00000555846.1
SOCS4
suppressor of cytokine signaling 4
chr10_-_100027943 0.30 ENST00000260702.3
LOXL4
lysyl oxidase-like 4
chr14_-_75593708 0.30 ENST00000557673.1
ENST00000238616.5
NEK9
NIMA-related kinase 9
chr15_+_85359911 0.30 ENST00000258888.5
ALPK3
alpha-kinase 3
chr14_+_75348592 0.30 ENST00000334220.4
DLST
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr3_+_119187785 0.29 ENST00000295588.4
ENST00000476573.1
POGLUT1
protein O-glucosyltransferase 1
chr7_+_138916231 0.29 ENST00000473989.3
ENST00000288561.8
UBN2
ubinuclein 2
chr6_-_86352642 0.29 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr18_-_51751132 0.29 ENST00000256429.3
MBD2
methyl-CpG binding domain protein 2
chr12_-_57400227 0.29 ENST00000300101.2
ZBTB39
zinc finger and BTB domain containing 39
chr10_+_115614370 0.29 ENST00000369301.3
NHLRC2
NHL repeat containing 2
chr5_+_151151471 0.29 ENST00000394123.3
ENST00000543466.1
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr8_+_21946681 0.28 ENST00000289921.7
FAM160B2
family with sequence similarity 160, member B2
chr13_+_49550015 0.28 ENST00000492622.2
FNDC3A
fibronectin type III domain containing 3A
chr3_+_171758344 0.28 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr13_-_110438914 0.28 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr9_-_74383799 0.28 ENST00000377044.4
TMEM2
transmembrane protein 2
chr6_-_3457256 0.28 ENST00000436008.2
SLC22A23
solute carrier family 22, member 23
chr12_-_49449107 0.27 ENST00000301067.7
KMT2D
lysine (K)-specific methyltransferase 2D

Network of associatons between targets according to the STRING database.

First level regulatory network of GAGGUAG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0044691 tooth eruption(GO:0044691)
0.5 1.4 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.5 1.8 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.4 1.3 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.4 1.6 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.4 1.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.4 1.5 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.4 1.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 1.6 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 2.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 2.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 1.3 GO:0061032 visceral serous pericardium development(GO:0061032)
0.2 0.9 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 0.7 GO:1901383 negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.2 1.1 GO:0001834 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.2 0.6 GO:0034059 response to anoxia(GO:0034059)
0.2 0.6 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.2 0.9 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 0.7 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 0.5 GO:1903249 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.2 0.9 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 0.2 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.2 0.9 GO:1990535 neuron projection maintenance(GO:1990535)
0.2 0.7 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 0.5 GO:1904316 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.2 0.8 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 1.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.4 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1 0.9 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.4 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.1 0.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:0097359 UDP-glucosylation(GO:0097359)
0.1 0.9 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.6 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 0.3 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 2.7 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.6 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.1 1.8 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.6 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 0.3 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.3 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.3 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.8 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.2 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.1 0.1 GO:0071926 endocannabinoid signaling pathway(GO:0071926)
0.1 0.5 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.3 GO:0051413 response to cortisone(GO:0051413)
0.1 0.2 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 1.2 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.8 GO:0060431 primary lung bud formation(GO:0060431)
0.1 0.2 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.9 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 2.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.2 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.8 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.6 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1 0.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.3 GO:0051414 response to cortisol(GO:0051414)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.0 0.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.5 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.6 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.3 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.3 GO:0001555 oocyte growth(GO:0001555)
0.0 0.5 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 1.0 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.3 GO:0030047 actin modification(GO:0030047)
0.0 0.3 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 1.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.0 0.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0035087 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.3 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.7 GO:0010225 response to UV-C(GO:0010225)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 1.5 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.6 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.2 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.2 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:1990926 vesicle-mediated cholesterol transport(GO:0090119) short-term synaptic potentiation(GO:1990926)
0.0 0.6 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.6 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:1904382 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.8 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.6 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.4 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.6 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.3 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.7 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 0.2 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.2 GO:1990440 ATF6-mediated unfolded protein response(GO:0036500) positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.0 0.1 GO:2000197 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.0 0.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.0 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.4 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.1 GO:1902022 lysine transport(GO:0015819) L-lysine transport(GO:1902022) L-lysine transmembrane transport(GO:1903401)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.2 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.6 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.3 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.3 GO:0002467 germinal center formation(GO:0002467)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.0 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.9 GO:0008542 visual learning(GO:0008542)
0.0 0.1 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0060346 bone trabecula formation(GO:0060346)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0005584 collagen type I trimer(GO:0005584)
0.7 2.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.4 1.1 GO:0005588 collagen type V trimer(GO:0005588)
0.3 2.9 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 3.4 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.3 0.8 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.2 1.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.9 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 1.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 1.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 1.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.0 GO:0060187 cell pole(GO:0060187)
0.0 2.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.8 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.6 GO:0000791 euchromatin(GO:0000791)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.3 1.7 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.3 7.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 0.9 GO:0071633 dihydroceramidase activity(GO:0071633)
0.3 0.9 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.3 1.5 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.2 0.7 GO:0038100 nodal binding(GO:0038100)
0.2 0.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 0.5 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.2 0.5 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.2 1.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.6 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.8 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.4 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.5 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.6 GO:0070051 fibrinogen binding(GO:0070051) collagen V binding(GO:0070052)
0.1 0.6 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.3 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.6 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 1.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.2 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.9 GO:0031995 insulin-like growth factor II binding(GO:0031995) PTB domain binding(GO:0051425)
0.1 1.6 GO:0070330 aromatase activity(GO:0070330)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 2.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.9 GO:0005165 neurotrophin receptor binding(GO:0005165)
0.1 0.2 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 2.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.2 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.6 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 1.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.4 GO:0045545 syndecan binding(GO:0045545)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.0 3.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.6 GO:0017111 nucleoside-triphosphatase activity(GO:0017111)
0.0 4.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.7 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.3 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.8 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.3 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.8 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 2.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.9 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.6 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 5.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 6.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 2.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.9 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.9 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.8 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha