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Illumina Body Map 2, young vs old

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Results for GLIS3

Z-value: 0.19

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Transcription factors associated with GLIS3

Gene Symbol Gene ID Gene Info
GLIS3
ENSG00000107249.17 GLIS family zinc finger 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS3hg19_v2_chr9_-_4299874_4299916-0.494.9e-03Click!

Activity profile of GLIS3 motif

Sorted Z-values of GLIS3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_57308979 2.82 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr2_-_211168332 1.95 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr10_+_105314881 1.84 ENST00000437579.1
NEURL
neuralized E3 ubiquitin protein ligase 1
chr14_+_105190514 1.33 ENST00000330877.2
ADSSL1
adenylosuccinate synthase like 1
chr19_+_1495362 1.16 ENST00000395479.4
REEP6
receptor accessory protein 6
chr1_+_31886653 1.13 ENST00000536384.1
SERINC2
serine incorporator 2
chr21_+_38071430 1.08 ENST00000290399.6
SIM2
single-minded family bHLH transcription factor 2
chr12_+_109577202 0.92 ENST00000377848.3
ENST00000377854.5
ACACB
acetyl-CoA carboxylase beta
chr19_-_10613862 0.87 ENST00000592055.1
KEAP1
kelch-like ECH-associated protein 1
chr6_+_24495185 0.75 ENST00000348925.2
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr5_+_17404114 0.74 ENST00000508677.1
RP11-321E2.3
RP11-321E2.3
chr6_+_24495067 0.71 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr19_-_10613421 0.70 ENST00000393623.2
KEAP1
kelch-like ECH-associated protein 1
chr19_-_10613361 0.66 ENST00000591039.1
ENST00000591419.1
KEAP1
kelch-like ECH-associated protein 1
chr18_+_11751493 0.63 ENST00000269162.5
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr18_+_11752040 0.63 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr15_-_43882140 0.62 ENST00000429176.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr1_-_42801540 0.59 ENST00000372573.1
FOXJ3
forkhead box J3
chr18_+_11751466 0.57 ENST00000535121.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr9_-_98279241 0.54 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
PTCH1
patched 1
chr17_+_80818231 0.54 ENST00000576996.1
TBCD
tubulin folding cofactor D
chr11_-_118789613 0.51 ENST00000532899.1
BCL9L
B-cell CLL/lymphoma 9-like
chr11_+_68671310 0.50 ENST00000255078.3
ENST00000539224.1
IGHMBP2
immunoglobulin mu binding protein 2
chr9_-_139658965 0.50 ENST00000316144.5
LCN15
lipocalin 15
chr3_+_127348005 0.48 ENST00000342480.6
PODXL2
podocalyxin-like 2
chr12_+_1929421 0.48 ENST00000543818.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr12_+_132312931 0.47 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr17_+_46018872 0.46 ENST00000583599.1
ENST00000434554.2
ENST00000225573.4
ENST00000544840.1
ENST00000534893.1
PNPO
pyridoxamine 5'-phosphate oxidase
chr15_-_43882353 0.46 ENST00000453080.1
ENST00000360301.4
ENST00000360135.4
ENST00000417085.1
ENST00000431962.1
ENST00000334933.4
ENST00000381879.4
ENST00000420765.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr1_-_247095236 0.45 ENST00000478568.1
AHCTF1
AT hook containing transcription factor 1
chr11_-_299519 0.44 ENST00000382614.2
IFITM5
interferon induced transmembrane protein 5
chr5_+_17404147 0.44 ENST00000507730.1
RP11-321E2.3
RP11-321E2.3
chr19_-_14224969 0.44 ENST00000589994.1
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr2_+_219824357 0.43 ENST00000302625.4
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr20_+_18447771 0.43 ENST00000377603.4
POLR3F
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr8_-_29120604 0.42 ENST00000521515.1
KIF13B
kinesin family member 13B
chr19_-_56092187 0.42 ENST00000325421.4
ENST00000592239.1
ZNF579
zinc finger protein 579
chr2_-_241737128 0.41 ENST00000404283.3
KIF1A
kinesin family member 1A
chr16_+_30006615 0.40 ENST00000563197.1
INO80E
INO80 complex subunit E
chr20_-_44718538 0.40 ENST00000290231.6
ENST00000372291.3
NCOA5
nuclear receptor coactivator 5
chr3_+_120626919 0.39 ENST00000273666.6
ENST00000471454.1
ENST00000472879.1
ENST00000497029.1
ENST00000492541.1
STXBP5L
syntaxin binding protein 5-like
chr17_-_5015129 0.39 ENST00000575898.1
ENST00000416429.2
ZNF232
zinc finger protein 232
chr19_-_48673465 0.38 ENST00000598938.1
LIG1
ligase I, DNA, ATP-dependent
chr9_-_116061476 0.38 ENST00000441031.3
RNF183
ring finger protein 183
chr19_+_11909329 0.38 ENST00000323169.5
ENST00000450087.1
ZNF491
zinc finger protein 491
chr1_-_42800860 0.37 ENST00000445886.1
ENST00000361346.1
ENST00000361776.1
FOXJ3
forkhead box J3
chr6_+_33172407 0.37 ENST00000374662.3
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr13_+_25670268 0.37 ENST00000281589.3
PABPC3
poly(A) binding protein, cytoplasmic 3
chr20_-_62103862 0.36 ENST00000344462.4
ENST00000357249.2
ENST00000359125.2
ENST00000360480.3
ENST00000370224.1
ENST00000344425.5
ENST00000354587.3
ENST00000359689.1
KCNQ2
potassium voltage-gated channel, KQT-like subfamily, member 2
chr14_+_22931924 0.36 ENST00000390477.2
TRDC
T cell receptor delta constant
chr3_-_160167508 0.35 ENST00000479460.1
TRIM59
tripartite motif containing 59
chr3_-_25824925 0.33 ENST00000396649.3
ENST00000428257.1
ENST00000280700.5
NGLY1
N-glycanase 1
chr11_+_1463728 0.32 ENST00000544817.1
BRSK2
BR serine/threonine kinase 2
chr17_-_79917645 0.32 ENST00000477214.1
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr10_+_71389983 0.31 ENST00000373279.4
C10orf35
chromosome 10 open reading frame 35
chr11_+_5646213 0.31 ENST00000429814.2
TRIM34
tripartite motif containing 34
chr19_-_13213954 0.31 ENST00000590974.1
LYL1
lymphoblastic leukemia derived sequence 1
chr1_+_59250815 0.30 ENST00000544621.1
ENST00000419531.2
RP4-794H19.2
long intergenic non-protein coding RNA 1135
chr3_-_160167301 0.29 ENST00000494486.1
TRIM59
tripartite motif containing 59
chr8_+_27183033 0.29 ENST00000420218.2
PTK2B
protein tyrosine kinase 2 beta
chr7_-_50518022 0.27 ENST00000356889.4
ENST00000420829.1
ENST00000448788.1
ENST00000395556.2
ENST00000422854.1
ENST00000435566.1
ENST00000433017.1
FIGNL1
fidgetin-like 1
chr8_-_74791051 0.27 ENST00000453587.2
ENST00000602969.1
ENST00000602593.1
ENST00000419880.3
ENST00000517608.1
UBE2W
ubiquitin-conjugating enzyme E2W (putative)
chr17_+_4675175 0.27 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr11_-_8680383 0.26 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr3_-_160167540 0.26 ENST00000496222.1
ENST00000471396.1
ENST00000471155.1
ENST00000309784.4
TRIM59
tripartite motif containing 59
chr1_+_110527308 0.25 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr2_-_241759622 0.25 ENST00000320389.7
ENST00000498729.2
KIF1A
kinesin family member 1A
chr8_-_29120580 0.25 ENST00000524189.1
KIF13B
kinesin family member 13B
chr15_+_84116106 0.25 ENST00000535412.1
ENST00000324537.5
SH3GL3
SH3-domain GRB2-like 3
chr2_+_220379052 0.24 ENST00000347842.3
ENST00000358078.4
ASIC4
acid-sensing (proton-gated) ion channel family member 4
chr1_-_160254913 0.24 ENST00000440949.3
ENST00000368072.5
ENST00000608310.1
ENST00000556710.1
PEX19
DCAF8
DCAF8
peroxisomal biogenesis factor 19
DDB1 and CUL4 associated factor 8
DDB1- and CUL4-associated factor 8
chr1_-_53018654 0.24 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11
zinc finger, CCHC domain containing 11
chr8_+_118147498 0.23 ENST00000519688.1
ENST00000456015.2
SLC30A8
solute carrier family 30 (zinc transporter), member 8
chr16_-_3285144 0.23 ENST00000431561.3
ENST00000396870.4
ZNF200
zinc finger protein 200
chr17_-_3819751 0.23 ENST00000225538.3
P2RX1
purinergic receptor P2X, ligand-gated ion channel, 1
chr8_+_11627205 0.22 ENST00000455213.2
ENST00000403422.3
ENST00000528323.1
ENST00000284503.6
NEIL2
nei endonuclease VIII-like 2 (E. coli)
chr7_+_23636992 0.22 ENST00000307471.3
ENST00000409765.1
CCDC126
coiled-coil domain containing 126
chr19_+_40697514 0.22 ENST00000253055.3
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr18_+_3451584 0.22 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr15_+_91478493 0.21 ENST00000418476.2
UNC45A
unc-45 homolog A (C. elegans)
chr17_+_48912744 0.21 ENST00000311378.4
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr5_+_172386419 0.21 ENST00000265100.2
ENST00000519239.1
RPL26L1
ribosomal protein L26-like 1
chr1_-_45988542 0.20 ENST00000424390.1
PRDX1
peroxiredoxin 1
chr1_-_53019059 0.19 ENST00000484723.2
ENST00000524582.1
ZCCHC11
zinc finger, CCHC domain containing 11
chr17_-_33446820 0.19 ENST00000592577.1
ENST00000590016.1
ENST00000345365.6
ENST00000360276.3
ENST00000357906.3
RAD51D
RAD51 paralog D
chr1_+_1950763 0.19 ENST00000378585.4
GABRD
gamma-aminobutyric acid (GABA) A receptor, delta
chr19_+_13875316 0.19 ENST00000319545.8
ENST00000593245.1
ENST00000040663.6
MRI1
methylthioribose-1-phosphate isomerase 1
chr22_-_32022280 0.18 ENST00000442379.1
PISD
phosphatidylserine decarboxylase
chr8_+_11627148 0.18 ENST00000436750.3
NEIL2
nei endonuclease VIII-like 2 (E. coli)
chr8_-_7220490 0.18 ENST00000400078.2
ZNF705G
zinc finger protein 705G
chr11_+_393428 0.17 ENST00000533249.1
ENST00000527442.1
PKP3
plakophilin 3
chr21_-_46330545 0.17 ENST00000320216.6
ENST00000397852.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_-_157108130 0.17 ENST00000368192.4
ETV3
ets variant 3
chr3_-_25824872 0.17 ENST00000308710.5
NGLY1
N-glycanase 1
chr5_+_172386517 0.16 ENST00000519522.1
RPL26L1
ribosomal protein L26-like 1
chr19_-_41859814 0.12 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr9_-_130742792 0.11 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr8_-_12051576 0.09 ENST00000524571.2
ENST00000533852.2
ENST00000533513.1
ENST00000448228.2
ENST00000534520.1
ENST00000321602.8
FAM86B1
family with sequence similarity 86, member B1
chr18_+_3451646 0.09 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr7_+_65958693 0.09 ENST00000445681.1
ENST00000452565.1
GS1-124K5.4
GS1-124K5.4
chr1_-_157108266 0.09 ENST00000326786.4
ETV3
ets variant 3
chr22_-_31742218 0.09 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr4_-_84255935 0.09 ENST00000513463.1
HPSE
heparanase
chr22_+_18834324 0.08 ENST00000342005.4
AC008132.13
Uncharacterized protein
chr1_+_16062820 0.08 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr19_-_48673552 0.07 ENST00000536218.1
ENST00000596549.1
LIG1
ligase I, DNA, ATP-dependent
chr22_+_50628999 0.07 ENST00000395827.1
TRABD
TraB domain containing
chr11_-_68671264 0.07 ENST00000362034.2
MRPL21
mitochondrial ribosomal protein L21
chr11_+_134855246 0.06 ENST00000597621.1
AP003062.1
CDNA FLJ27342 fis, clone TST02993; Uncharacterized protein
chr17_-_73178599 0.05 ENST00000578238.1
SUMO2
small ubiquitin-like modifier 2
chr22_-_50964849 0.05 ENST00000543927.1
ENST00000423348.1
SCO2
SCO2 cytochrome c oxidase assembly protein
chr5_+_157098534 0.05 ENST00000409999.3
C5orf52
chromosome 5 open reading frame 52
chrX_+_118370288 0.04 ENST00000535419.1
PGRMC1
progesterone receptor membrane component 1
chr11_+_68451943 0.02 ENST00000265643.3
GAL
galanin/GMAP prepropeptide
chrX_+_118370211 0.02 ENST00000217971.7
PGRMC1
progesterone receptor membrane component 1
chr12_-_57400227 0.02 ENST00000300101.2
ZBTB39
zinc finger and BTB domain containing 39
chr14_+_77228532 0.02 ENST00000167106.4
ENST00000554237.1
VASH1
vasohibin 1
chr7_-_127032114 0.01 ENST00000436992.1
ZNF800
zinc finger protein 800
chr5_-_180671172 0.01 ENST00000512805.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr19_+_46850251 0.01 ENST00000012443.4
PPP5C
protein phosphatase 5, catalytic subunit
chr5_+_41925325 0.01 ENST00000296812.2
ENST00000281623.3
ENST00000509134.1
FBXO4
F-box protein 4

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 1.5 GO:0006540 glutamate decarboxylation to succinate(GO:0006540) gamma-aminobutyric acid catabolic process(GO:0009450)
0.2 1.1 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 0.9 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 0.5 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.1 2.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.4 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.5 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.5 GO:0010157 response to chlorate(GO:0010157)
0.1 0.3 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 1.8 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 2.8 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.7 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 1.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0002554 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.5 GO:0042756 drinking behavior(GO:0042756)
0.0 0.3 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.1 GO:0075528 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0 1.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.9 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.4 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.4 GO:0045008 depyrimidination(GO:0045008)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 2.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.3 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.3 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.2 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.3 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.5 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.7 GO:0008089 anterograde axonal transport(GO:0008089)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.5 GO:0044294 dendritic growth cone(GO:0044294)
0.1 2.8 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 2.0 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:0032797 SMN complex(GO:0032797)
0.0 0.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.7 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 2.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.2 0.5 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.2 0.9 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.4 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 1.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.4 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.3 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 0.5 GO:0005119 smoothened binding(GO:0005119)
0.1 0.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 1.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 1.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0030305 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.0 0.5 GO:0010181 FMN binding(GO:0010181)
0.0 1.5 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 2.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.5 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix