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Illumina Body Map 2, young vs old

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Results for GUAAACA

Z-value: 0.42

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miRNA associated with seed GUAAACA

NamemiRBASE accession
hsa-miR-30a-5p
MIMAT0000087
hsa-miR-30b-5p
MIMAT0000420
hsa-miR-30c-5p
MIMAT0000244
hsa-miR-30d-5p
MIMAT0000245
hsa-miR-30e-5p
MIMAT0000692

Activity profile of GUAAACA motif

Sorted Z-values of GUAAACA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_52495426 1.84 ENST00000262094.5
RAB27B
RAB27B, member RAS oncogene family
chr5_+_110559784 1.71 ENST00000282356.4
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr7_-_27224795 1.45 ENST00000006015.3
HOXA11
homeobox A11
chr14_-_99737565 1.32 ENST00000357195.3
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr14_-_24047965 1.27 ENST00000397118.3
ENST00000356300.4
JPH4
junctophilin 4
chr6_-_40555176 1.26 ENST00000338305.6
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr1_+_50574585 1.24 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr9_-_23821273 1.13 ENST00000380110.4
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr7_-_143059845 1.09 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr6_-_30654977 1.02 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr1_-_200992827 1.01 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr8_+_24772455 1.00 ENST00000433454.2
NEFM
neurofilament, medium polypeptide
chr10_+_95517566 0.98 ENST00000542308.1
LGI1
leucine-rich, glioma inactivated 1
chr1_+_12123414 0.98 ENST00000263932.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr6_+_45389893 0.97 ENST00000371432.3
RUNX2
runt-related transcription factor 2
chr16_-_30022293 0.97 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
DOC2A
double C2-like domains, alpha
chr1_-_220101944 0.96 ENST00000366926.3
ENST00000536992.1
SLC30A10
solute carrier family 30, member 10
chr12_+_94542459 0.93 ENST00000258526.4
PLXNC1
plexin C1
chr16_+_28303804 0.89 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr19_+_18208603 0.88 ENST00000262811.6
MAST3
microtubule associated serine/threonine kinase 3
chr2_-_235405679 0.87 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr16_+_2039946 0.86 ENST00000248121.2
ENST00000568896.1
SYNGR3
synaptogyrin 3
chr15_-_34628951 0.86 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr2_-_175499294 0.85 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chr5_-_157002775 0.82 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr19_-_4066890 0.82 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chr7_-_27219632 0.82 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chr4_-_42154895 0.81 ENST00000502486.1
ENST00000504360.1
BEND4
BEN domain containing 4
chr5_-_72744336 0.80 ENST00000499003.3
FOXD1
forkhead box D1
chr6_+_117198400 0.80 ENST00000332958.2
RFX6
regulatory factor X, 6
chr19_-_11450249 0.80 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr2_-_100721178 0.80 ENST00000409236.2
AFF3
AF4/FMR2 family, member 3
chr5_-_132948216 0.78 ENST00000265342.7
FSTL4
follistatin-like 4
chr2_+_176972000 0.78 ENST00000249504.5
HOXD11
homeobox D11
chr4_+_174089904 0.78 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr2_-_182545603 0.78 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr19_+_926000 0.76 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr10_-_23003460 0.76 ENST00000376573.4
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr15_-_65579177 0.75 ENST00000444347.2
ENST00000261888.6
PARP16
poly (ADP-ribose) polymerase family, member 16
chr3_-_150481164 0.75 ENST00000312960.3
SIAH2
siah E3 ubiquitin protein ligase 2
chr14_-_38064198 0.74 ENST00000250448.2
FOXA1
forkhead box A1
chr6_-_16761678 0.74 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr4_+_57138437 0.74 ENST00000504228.1
ENST00000541073.1
KIAA1211
KIAA1211
chr3_-_18466787 0.73 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr7_+_66093851 0.73 ENST00000275532.3
KCTD7
potassium channel tetramerization domain containing 7
chr6_+_105404899 0.72 ENST00000345080.4
LIN28B
lin-28 homolog B (C. elegans)
chr16_+_56225248 0.71 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr22_+_21271714 0.71 ENST00000354336.3
CRKL
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr1_-_151688528 0.70 ENST00000290585.4
CELF3
CUGBP, Elav-like family member 3
chr2_-_16847084 0.69 ENST00000406434.1
ENST00000381323.3
FAM49A
family with sequence similarity 49, member A
chr2_-_166651191 0.67 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr1_+_244214577 0.67 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr20_-_30795511 0.67 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr12_-_53625958 0.67 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG
retinoic acid receptor, gamma
chr10_+_73079000 0.67 ENST00000373189.5
SLC29A3
solute carrier family 29 (equilibrative nucleoside transporter), member 3
chr17_-_29151794 0.67 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chr11_+_65554493 0.66 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chrX_+_72223352 0.66 ENST00000373521.2
ENST00000538388.1
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2B
chr1_+_205012293 0.66 ENST00000331830.4
CNTN2
contactin 2 (axonal)
chr5_-_147162078 0.66 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chrX_+_103810874 0.65 ENST00000372582.1
IL1RAPL2
interleukin 1 receptor accessory protein-like 2
chr1_+_155051305 0.65 ENST00000368408.3
EFNA3
ephrin-A3
chr1_+_197881592 0.65 ENST00000367391.1
ENST00000367390.3
LHX9
LIM homeobox 9
chr6_-_42419649 0.65 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1
transcriptional regulating factor 1
chr6_+_146864829 0.65 ENST00000367495.3
RAB32
RAB32, member RAS oncogene family
chr17_+_35294075 0.64 ENST00000254457.5
LHX1
LIM homeobox 1
chr1_+_90286562 0.64 ENST00000525774.1
ENST00000337338.5
LRRC8D
leucine rich repeat containing 8 family, member D
chr22_-_37823468 0.64 ENST00000402918.2
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr2_+_166095898 0.64 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr7_-_123673471 0.64 ENST00000455783.1
TMEM229A
transmembrane protein 229A
chr12_-_90049828 0.64 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr11_+_46354455 0.63 ENST00000343674.6
DGKZ
diacylglycerol kinase, zeta
chr6_+_64281906 0.63 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr21_+_30671189 0.63 ENST00000286800.3
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr18_+_60190226 0.63 ENST00000269499.5
ZCCHC2
zinc finger, CCHC domain containing 2
chr14_+_103058948 0.63 ENST00000262241.6
RCOR1
REST corepressor 1
chr22_+_40573921 0.62 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr1_-_89591749 0.62 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr1_-_115632035 0.61 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2
tetraspanin 2
chr8_-_124553437 0.61 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr4_-_102268628 0.60 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_+_32859510 0.60 ENST00000383763.5
TRIM71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr14_-_93582148 0.60 ENST00000267615.6
ENST00000553452.1
ITPK1
inositol-tetrakisphosphate 1-kinase
chr2_+_32288725 0.60 ENST00000315285.3
SPAST
spastin
chr12_+_104458235 0.59 ENST00000229330.4
HCFC2
host cell factor C2
chr5_-_37839782 0.59 ENST00000326524.2
ENST00000515058.1
GDNF
glial cell derived neurotrophic factor
chr16_+_29823552 0.59 ENST00000300797.6
PRRT2
proline-rich transmembrane protein 2
chr1_+_221051699 0.58 ENST00000366903.6
HLX
H2.0-like homeobox
chr7_+_87505544 0.57 ENST00000265728.1
DBF4
DBF4 homolog (S. cerevisiae)
chr22_-_17602200 0.57 ENST00000399875.1
CECR6
cat eye syndrome chromosome region, candidate 6
chr3_+_141205852 0.57 ENST00000286364.3
ENST00000452898.1
RASA2
RAS p21 protein activator 2
chr7_+_128784712 0.57 ENST00000289407.4
TSPAN33
tetraspanin 33
chr16_-_84651673 0.56 ENST00000262428.4
COTL1
coactosin-like 1 (Dictyostelium)
chr7_+_18535346 0.56 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9
histone deacetylase 9
chr7_-_27205136 0.56 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr10_-_94003003 0.55 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr17_-_63052929 0.55 ENST00000439174.2
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr1_+_113217043 0.54 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr15_+_52043758 0.54 ENST00000249700.4
ENST00000539962.2
TMOD2
tropomodulin 2 (neuronal)
chr11_-_134281812 0.54 ENST00000392580.1
ENST00000312527.4
B3GAT1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr6_+_391739 0.53 ENST00000380956.4
IRF4
interferon regulatory factor 4
chr6_+_137243373 0.52 ENST00000331858.4
SLC35D3
solute carrier family 35, member D3
chr10_+_106400859 0.52 ENST00000369701.3
SORCS3
sortilin-related VPS10 domain containing receptor 3
chr6_+_114178512 0.52 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chrX_+_100474711 0.51 ENST00000402866.1
DRP2
dystrophin related protein 2
chr2_-_25475120 0.51 ENST00000380746.4
ENST00000402667.1
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr1_-_85156216 0.51 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr12_+_101188547 0.51 ENST00000546991.1
ENST00000392979.3
ANO4
anoctamin 4
chr12_-_77459306 0.51 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F7
E2F transcription factor 7
chr1_+_147013182 0.51 ENST00000234739.3
BCL9
B-cell CLL/lymphoma 9
chr7_-_55640176 0.50 ENST00000285279.5
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr15_-_52821247 0.50 ENST00000399231.3
ENST00000399233.2
MYO5A
myosin VA (heavy chain 12, myoxin)
chr5_-_56247935 0.50 ENST00000381199.3
ENST00000381226.3
ENST00000381213.3
MIER3
mesoderm induction early response 1, family member 3
chr12_-_104234966 0.50 ENST00000392876.3
NT5DC3
5'-nucleotidase domain containing 3
chr5_-_134369973 0.48 ENST00000265340.7
PITX1
paired-like homeodomain 1
chr10_-_32636106 0.48 ENST00000263062.8
ENST00000319778.6
EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr1_-_108507631 0.48 ENST00000527011.1
ENST00000370056.4
VAV3
vav 3 guanine nucleotide exchange factor
chr20_-_21494654 0.48 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chr1_+_6484829 0.48 ENST00000377828.1
ESPN
espin
chr9_-_3525968 0.47 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr18_-_12702769 0.47 ENST00000262127.2
CEP76
centrosomal protein 76kDa
chr1_-_19283163 0.47 ENST00000455833.2
IFFO2
intermediate filament family orphan 2
chr3_-_98312548 0.47 ENST00000264193.2
CPOX
coproporphyrinogen oxidase
chr3_+_49591881 0.47 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr6_+_106546808 0.47 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr12_+_57916466 0.46 ENST00000355673.3
MBD6
methyl-CpG binding domain protein 6
chr14_-_69446034 0.46 ENST00000193403.6
ACTN1
actinin, alpha 1
chr7_+_21467642 0.46 ENST00000222584.3
ENST00000432066.2
SP4
Sp4 transcription factor
chr6_+_160390102 0.46 ENST00000356956.1
IGF2R
insulin-like growth factor 2 receptor
chr3_-_129407535 0.46 ENST00000432054.2
TMCC1
transmembrane and coiled-coil domain family 1
chr11_+_94277017 0.46 ENST00000358752.2
FUT4
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr2_-_26205340 0.45 ENST00000264712.3
KIF3C
kinesin family member 3C
chr1_+_107683644 0.45 ENST00000370067.1
NTNG1
netrin G1
chr8_-_33424636 0.45 ENST00000256257.1
RNF122
ring finger protein 122
chr2_-_176948641 0.45 ENST00000308618.4
EVX2
even-skipped homeobox 2
chr17_+_42634844 0.45 ENST00000315323.3
FZD2
frizzled family receptor 2
chr12_-_122751002 0.45 ENST00000267199.4
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr5_-_100238956 0.45 ENST00000231461.5
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr6_-_90062543 0.45 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr17_-_42200996 0.45 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
HDAC5
histone deacetylase 5
chr5_+_179159813 0.45 ENST00000292599.3
MAML1
mastermind-like 1 (Drosophila)
chr6_-_13711773 0.44 ENST00000011619.3
RANBP9
RAN binding protein 9
chr12_-_53893399 0.44 ENST00000267079.2
MAP3K12
mitogen-activated protein kinase kinase kinase 12
chr18_+_54318616 0.44 ENST00000254442.3
WDR7
WD repeat domain 7
chr1_-_116383738 0.44 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chr5_+_56111361 0.44 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr15_+_60296421 0.43 ENST00000396057.4
FOXB1
forkhead box B1
chr12_-_76953284 0.43 ENST00000547544.1
ENST00000393249.2
OSBPL8
oxysterol binding protein-like 8
chr2_-_200322723 0.43 ENST00000417098.1
SATB2
SATB homeobox 2
chr19_-_6110474 0.43 ENST00000587181.1
ENST00000587321.1
ENST00000586806.1
ENST00000589742.1
ENST00000592546.1
ENST00000303657.5
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr11_-_116968987 0.43 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3
SIK family kinase 3
chr10_+_64893039 0.42 ENST00000277746.6
ENST00000435510.2
NRBF2
nuclear receptor binding factor 2
chr1_+_174769006 0.42 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr1_-_6240183 0.42 ENST00000262450.3
ENST00000378021.1
CHD5
chromodomain helicase DNA binding protein 5
chr20_-_60982330 0.42 ENST00000279101.5
CABLES2
Cdk5 and Abl enzyme substrate 2
chr18_+_55102917 0.42 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr12_-_85306594 0.41 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr20_+_58508817 0.41 ENST00000358293.3
FAM217B
family with sequence similarity 217, member B
chr4_+_40058411 0.41 ENST00000261435.6
ENST00000515550.1
N4BP2
NEDD4 binding protein 2
chr2_-_24149977 0.41 ENST00000238789.5
ATAD2B
ATPase family, AAA domain containing 2B
chr3_-_52312636 0.41 ENST00000296490.3
WDR82
WD repeat domain 82
chr20_+_54933971 0.40 ENST00000371384.3
ENST00000437418.1
FAM210B
family with sequence similarity 210, member B
chr13_-_50367057 0.40 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr2_-_68479614 0.40 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr6_-_20212630 0.40 ENST00000324607.7
ENST00000541730.1
ENST00000536798.1
MBOAT1
membrane bound O-acyltransferase domain containing 1
chr8_-_116681221 0.40 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr3_-_182698381 0.40 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr14_-_74253948 0.40 ENST00000394071.2
ELMSAN1
ELM2 and Myb/SANT-like domain containing 1
chr1_-_197169672 0.39 ENST00000367405.4
ZBTB41
zinc finger and BTB domain containing 41
chr18_-_67624160 0.39 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr10_-_48416849 0.39 ENST00000249598.1
GDF2
growth differentiation factor 2
chr10_-_60027642 0.39 ENST00000373935.3
IPMK
inositol polyphosphate multikinase
chr1_+_179923873 0.39 ENST00000367607.3
ENST00000491495.2
CEP350
centrosomal protein 350kDa
chr2_-_209119831 0.39 ENST00000345146.2
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr6_-_45345597 0.39 ENST00000371460.1
ENST00000371459.1
SUPT3H
suppressor of Ty 3 homolog (S. cerevisiae)
chr2_+_102508955 0.39 ENST00000414004.2
FLJ20373
FLJ20373
chrX_-_39956656 0.38 ENST00000397354.3
ENST00000378444.4
BCOR
BCL6 corepressor
chr22_+_21771656 0.38 ENST00000407464.2
HIC2
hypermethylated in cancer 2
chr8_+_107670064 0.38 ENST00000312046.6
OXR1
oxidation resistance 1
chr1_+_15943995 0.38 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr19_+_41816053 0.38 ENST00000269967.3
CCDC97
coiled-coil domain containing 97
chr16_+_50187556 0.38 ENST00000561678.1
ENST00000357464.3
PAPD5
PAP associated domain containing 5
chr14_-_58332774 0.37 ENST00000556826.1
SLC35F4
solute carrier family 35, member F4
chr19_+_18263928 0.37 ENST00000222254.8
PIK3R2
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
chr7_-_27135591 0.37 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr9_-_115095883 0.37 ENST00000450374.1
ENST00000374255.2
ENST00000334318.6
ENST00000374257.1
PTBP3
polypyrimidine tract binding protein 3
chr2_-_169104651 0.37 ENST00000355999.4
STK39
serine threonine kinase 39
chr22_-_50913371 0.37 ENST00000348911.6
ENST00000380817.3
ENST00000390679.3
SBF1
SET binding factor 1
chr1_+_118148556 0.37 ENST00000369448.3
FAM46C
family with sequence similarity 46, member C
chr3_-_183979251 0.36 ENST00000296238.3
CAMK2N2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr3_+_36421826 0.36 ENST00000273183.3
STAC
SH3 and cysteine rich domain
chr3_+_196295482 0.36 ENST00000440469.1
ENST00000311630.6
FBXO45
F-box protein 45
chr22_+_50247449 0.36 ENST00000216268.5
ZBED4
zinc finger, BED-type containing 4
chr7_-_149194843 0.36 ENST00000458143.2
ENST00000340622.3
ZNF746
zinc finger protein 746
chr1_-_234745234 0.35 ENST00000366610.3
ENST00000366609.3
IRF2BP2
interferon regulatory factor 2 binding protein 2
chr17_-_74449252 0.35 ENST00000319380.7
UBE2O
ubiquitin-conjugating enzyme E2O
chr17_-_65241281 0.35 ENST00000358691.5
ENST00000580168.1
HELZ
helicase with zinc finger
chr3_+_180630090 0.35 ENST00000357559.4
ENST00000305586.7
FXR1
fragile X mental retardation, autosomal homolog 1
chr14_+_53196872 0.35 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr9_-_16870704 0.35 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAAACA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.4 1.3 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.3 1.0 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.3 1.0 GO:0045554 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.3 0.8 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.2 0.7 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.2 0.7 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.2 0.6 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.2 0.6 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.2 0.8 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.2 0.6 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.2 0.5 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 0.9 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 0.5 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.2 0.5 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.2 0.7 GO:0060168 regulation of axon diameter(GO:0031133) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.2 0.7 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 0.8 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 0.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.8 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.2 0.5 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.6 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.7 GO:0003162 atrioventricular node development(GO:0003162)
0.1 1.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.7 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.6 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.4 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016) negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 1.3 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.6 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 0.5 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 0.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.1 0.9 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 0.4 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.5 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 1.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.3 GO:0050904 diapedesis(GO:0050904)
0.1 0.5 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.6 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.4 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 1.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.3 GO:0070666 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.6 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.1 1.3 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.3 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.5 GO:0051643 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) endoplasmic reticulum localization(GO:0051643)
0.1 0.3 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.1 0.3 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.2 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.5 GO:0003150 membranous septum morphogenesis(GO:0003149) muscular septum morphogenesis(GO:0003150)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.7 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.3 GO:0060374 mast cell differentiation(GO:0060374)
0.1 0.5 GO:0071440 regulation of histone H3-K14 acetylation(GO:0071440)
0.1 0.3 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 1.8 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.5 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 1.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.4 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.6 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.5 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 0.7 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 0.5 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.2 GO:0006043 glucosamine catabolic process(GO:0006043)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.1 0.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.6 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.9 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 1.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.0 GO:0072054 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0 0.5 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.7 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.2 GO:0046619 optic placode formation(GO:0001743) optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.7 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.4 GO:0021902 forebrain neuron fate commitment(GO:0021877) commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.9 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.1 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.0 1.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0 0.3 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.4 GO:0043634 polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.6 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.0 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.6 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.1 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.4 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.7 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.5 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.2 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.0 0.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.5 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.7 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 0.2 GO:0048511 rhythmic process(GO:0048511)
0.0 0.2 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.4 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.2 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.3 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.4 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.3 GO:0035973 aggrephagy(GO:0035973)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.3 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.5 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.6 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.5 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.4 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.1 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 1.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.6 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.4 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.5 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.2 GO:0021930 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.0 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.0 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.2 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.1 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.3 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.0 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.4 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0071926 endocannabinoid signaling pathway(GO:0071926)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.8 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.2 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.4 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0031929 TOR signaling(GO:0031929)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.4 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 1.1 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.4 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.1 GO:0014029 neural crest formation(GO:0014029)
0.0 0.3 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.3 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 1.0 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.0 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.0 0.1 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.5 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.6 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.1 1.1 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.6 GO:0031905 early endosome lumen(GO:0031905)
0.1 1.8 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.7 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.3 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.9 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.6 GO:0042025 host cell nucleus(GO:0042025)
0.1 0.9 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.5 GO:0071203 WASH complex(GO:0071203)
0.1 0.2 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.1 0.2 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.0 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.3 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.4 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.3 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 1.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0031213 RSF complex(GO:0031213)
0.0 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.7 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.7 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 3.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.9 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 2.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.6 GO:0090544 BAF-type complex(GO:0090544)
0.0 1.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.5 GO:0031300 intrinsic component of organelle membrane(GO:0031300)
0.0 1.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 1.0 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.2 0.5 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.2 0.6 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.4 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.7 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.4 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.4 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.4 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 3.0 GO:0031489 myosin V binding(GO:0031489)
0.1 0.3 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.0 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.2 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 1.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.9 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.1 GO:0052827 inositol pentakisphosphate phosphatase activity(GO:0052827)
0.1 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 1.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.2 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 0.5 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.2 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.1 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 2.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.6 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 1.0 GO:0035198 miRNA binding(GO:0035198)
0.0 1.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 1.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.8 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.5 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 1.1 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.5 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0031692 alpha-1B adrenergic receptor binding(GO:0031692)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 2.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 1.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 2.1 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.0 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.2 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.3 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.7 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 4.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 2.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 3.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.6 PID FOXO PATHWAY FoxO family signaling
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 0.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 2.7 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 1.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains