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Illumina Body Map 2, young vs old

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Results for HES7_HES5

Z-value: 0.02

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Transcription factors associated with HES7_HES5

Gene Symbol Gene ID Gene Info
HES7
ENSG00000179111.4 hes family bHLH transcription factor 7
HES5
ENSG00000197921.5 hes family bHLH transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HES7hg19_v2_chr17_-_8027402_80274320.647.1e-05Click!
HES5hg19_v2_chr1_-_2461684_24617100.392.9e-02Click!

Activity profile of HES7_HES5 motif

Sorted Z-values of HES7_HES5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_26233423 4.01 ENST00000357865.2
STMN1
stathmin 1
chr14_-_77737543 3.61 ENST00000298352.4
NGB
neuroglobin
chr19_+_4304585 3.54 ENST00000221856.6
FSD1
fibronectin type III and SPRY domain containing 1
chr19_+_4304632 3.53 ENST00000597590.1
FSD1
fibronectin type III and SPRY domain containing 1
chr1_-_26232951 3.51 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr1_-_26232522 3.35 ENST00000399728.1
STMN1
stathmin 1
chr1_+_16083098 2.99 ENST00000496928.2
ENST00000508310.1
FBLIM1
filamin binding LIM protein 1
chr1_+_16083154 2.63 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr4_-_6202291 2.48 ENST00000282924.5
JAKMIP1
janus kinase and microtubule interacting protein 1
chr1_+_16083123 2.41 ENST00000510393.1
ENST00000430076.1
FBLIM1
filamin binding LIM protein 1
chr19_-_19739007 2.33 ENST00000586703.1
ENST00000591042.1
ENST00000407877.3
LPAR2
lysophosphatidic acid receptor 2
chr5_+_152870106 2.17 ENST00000285900.5
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr2_-_132919528 2.11 ENST00000409867.1
ANKRD30BL
ankyrin repeat domain 30B-like
chr4_-_6202247 2.08 ENST00000409021.3
ENST00000409371.3
JAKMIP1
janus kinase and microtubule interacting protein 1
chr17_-_42907564 2.08 ENST00000592524.1
GJC1
gap junction protein, gamma 1, 45kDa
chr1_+_210111534 2.04 ENST00000422431.1
ENST00000534859.1
ENST00000399639.2
ENST00000537238.1
SYT14
synaptotagmin XIV
chr8_+_104383728 1.94 ENST00000330295.5
CTHRC1
collagen triple helix repeat containing 1
chr2_-_219925189 1.85 ENST00000295731.6
IHH
indian hedgehog
chr19_+_4304685 1.84 ENST00000601006.1
FSD1
fibronectin type III and SPRY domain containing 1
chr6_+_122931366 1.76 ENST00000368452.2
ENST00000368448.1
ENST00000392490.1
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr5_+_152870215 1.68 ENST00000518142.1
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr12_-_91348949 1.61 ENST00000358859.2
CCER1
coiled-coil glutamate-rich protein 1
chr20_-_2821271 1.57 ENST00000448755.1
ENST00000360652.2
PCED1A
PC-esterase domain containing 1A
chr1_-_109655377 1.57 ENST00000369948.3
C1orf194
chromosome 1 open reading frame 194
chr5_-_54529415 1.55 ENST00000282572.4
CCNO
cyclin O
chr11_+_60197040 1.54 ENST00000300190.2
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr2_-_27486951 1.50 ENST00000432351.1
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr1_+_28261621 1.49 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr14_+_65879437 1.49 ENST00000394585.1
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr5_+_152870287 1.47 ENST00000340592.5
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr4_-_144940477 1.43 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
GYPB
glycophorin B (MNS blood group)
chr20_+_45523227 1.37 ENST00000327619.5
ENST00000357410.3
EYA2
eyes absent homolog 2 (Drosophila)
chr14_+_104689918 1.37 ENST00000553757.1
ENST00000556528.1
ENST00000555282.1
RP11-260M19.2
RP11-260M19.2
chr1_+_28261492 1.35 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr5_+_143550396 1.32 ENST00000512467.1
KCTD16
potassium channel tetramerization domain containing 16
chr19_+_6135646 1.32 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr3_-_189840223 1.27 ENST00000427335.2
LEPREL1
leprecan-like 1
chr1_+_28261533 1.26 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chrX_+_152224766 1.25 ENST00000370265.4
ENST00000447306.1
PNMA3
paraneoplastic Ma antigen 3
chr13_+_35516390 1.19 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
NBEA
neurobeachin
chr14_+_65879668 1.19 ENST00000553924.1
ENST00000358307.2
ENST00000557338.1
ENST00000554610.1
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr2_+_27665232 1.18 ENST00000543753.1
ENST00000288873.3
KRTCAP3
keratinocyte associated protein 3
chr11_+_60197069 1.16 ENST00000528905.1
ENST00000528093.1
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr1_+_210111570 1.16 ENST00000367019.1
ENST00000472886.1
SYT14
synaptotagmin XIV
chr16_+_222846 1.15 ENST00000251595.6
ENST00000397806.1
HBA2
hemoglobin, alpha 2
chrX_-_16887963 1.14 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr17_-_42908155 1.09 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1
gap junction protein, gamma 1, 45kDa
chr7_-_73184588 1.08 ENST00000395145.2
CLDN3
claudin 3
chr11_-_26593649 1.07 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr4_-_144826682 1.01 ENST00000358615.4
ENST00000437468.2
GYPE
glycophorin E (MNS blood group)
chr12_-_123728548 1.00 ENST00000545406.1
MPHOSPH9
M-phase phosphoprotein 9
chrX_-_48326764 0.98 ENST00000413668.1
ENST00000441948.1
SLC38A5
solute carrier family 38, member 5
chr4_+_76439649 0.98 ENST00000507557.1
THAP6
THAP domain containing 6
chr6_+_13182751 0.97 ENST00000415087.1
PHACTR1
phosphatase and actin regulator 1
chr9_-_23821842 0.97 ENST00000544538.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr16_-_5115913 0.95 ENST00000474471.3
C16orf89
chromosome 16 open reading frame 89
chr20_+_44650348 0.94 ENST00000454036.2
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr1_+_166958504 0.93 ENST00000447624.1
MAEL
maelstrom spermatogenic transposon silencer
chr3_+_39851094 0.93 ENST00000302541.6
MYRIP
myosin VIIA and Rab interacting protein
chr1_+_166958497 0.91 ENST00000367870.2
MAEL
maelstrom spermatogenic transposon silencer
chr12_-_10320256 0.90 ENST00000538745.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr17_+_30813576 0.90 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr22_+_30752963 0.89 ENST00000445005.1
ENST00000430839.1
CCDC157
coiled-coil domain containing 157
chr19_-_55458860 0.88 ENST00000592784.1
ENST00000448121.2
ENST00000340844.2
NLRP7
NLR family, pyrin domain containing 7
chrX_+_134124968 0.86 ENST00000330288.4
SMIM10
small integral membrane protein 10
chr14_-_106967788 0.86 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chr14_+_94385235 0.86 ENST00000557719.1
ENST00000267594.5
FAM181A
family with sequence similarity 181, member A
chr1_+_44457441 0.84 ENST00000466180.1
CCDC24
coiled-coil domain containing 24
chr14_+_24641062 0.82 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
REC8
REC8 meiotic recombination protein
chr5_+_78532003 0.80 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr2_+_27665289 0.78 ENST00000407293.1
KRTCAP3
keratinocyte associated protein 3
chr4_+_94750014 0.77 ENST00000306011.3
ATOH1
atonal homolog 1 (Drosophila)
chr1_-_201476220 0.76 ENST00000526723.1
ENST00000524951.1
CSRP1
cysteine and glycine-rich protein 1
chr8_+_104383759 0.71 ENST00000415886.2
CTHRC1
collagen triple helix repeat containing 1
chr19_-_3700388 0.70 ENST00000589578.1
ENST00000537021.1
ENST00000539785.1
ENST00000335312.3
PIP5K1C
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
chr4_+_2965307 0.70 ENST00000398051.4
ENST00000503518.2
ENST00000398052.4
ENST00000345167.6
ENST00000504933.1
ENST00000442472.2
GRK4
G protein-coupled receptor kinase 4
chr1_-_166944652 0.69 ENST00000528703.1
ENST00000525740.1
ENST00000529387.1
ENST00000469934.2
ENST00000529071.1
ENST00000526687.1
ILDR2
immunoglobulin-like domain containing receptor 2
chr1_-_166944561 0.65 ENST00000271417.3
ILDR2
immunoglobulin-like domain containing receptor 2
chr2_-_232328867 0.65 ENST00000453992.1
ENST00000417652.1
ENST00000454824.1
NCL
nucleolin
chr2_-_175870085 0.64 ENST00000409156.3
CHN1
chimerin 1
chr11_-_26593677 0.63 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr4_-_145061788 0.63 ENST00000512064.1
ENST00000512789.1
ENST00000504786.1
ENST00000503627.1
ENST00000535709.1
ENST00000324022.10
ENST00000360771.4
ENST00000283126.7
GYPA
GYPB
glycophorin A (MNS blood group)
glycophorin B (MNS blood group)
chr1_+_179561011 0.62 ENST00000294848.8
ENST00000444136.1
TDRD5
tudor domain containing 5
chr21_+_42694732 0.61 ENST00000398646.3
FAM3B
family with sequence similarity 3, member B
chr2_+_86116396 0.61 ENST00000455121.3
AC105053.4
AC105053.4
chrX_-_48326683 0.60 ENST00000440085.1
SLC38A5
solute carrier family 38, member 5
chr13_+_115047097 0.59 ENST00000351487.5
UPF3A
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr14_+_65878650 0.59 ENST00000555559.1
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr16_+_333152 0.58 ENST00000219406.6
ENST00000404312.1
ENST00000456379.1
PDIA2
protein disulfide isomerase family A, member 2
chr20_+_36012051 0.57 ENST00000373567.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr1_-_201476274 0.54 ENST00000340006.2
CSRP1
cysteine and glycine-rich protein 1
chr2_+_25264933 0.53 ENST00000401432.3
ENST00000403714.3
EFR3B
EFR3 homolog B (S. cerevisiae)
chr9_+_100174344 0.52 ENST00000422139.2
TDRD7
tudor domain containing 7
chr22_-_50523760 0.52 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr4_+_6202448 0.51 ENST00000508601.1
RP11-586D19.1
RP11-586D19.1
chr4_+_9446156 0.51 ENST00000334879.1
DEFB131
defensin, beta 131
chr9_+_103204553 0.51 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr3_+_38537763 0.51 ENST00000287675.5
ENST00000358249.2
ENST00000422077.2
EXOG
endo/exonuclease (5'-3'), endonuclease G-like
chr7_+_99202003 0.50 ENST00000609449.1
GS1-259H13.2
GS1-259H13.2
chr2_-_86564776 0.50 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr19_-_53632925 0.49 ENST00000595174.1
ZNF415
zinc finger protein 415
chr22_+_42095497 0.48 ENST00000401548.3
ENST00000540833.1
ENST00000400107.1
ENST00000300398.4
MEI1
meiosis inhibitor 1
chr4_-_76439483 0.48 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr7_-_130598059 0.47 ENST00000432045.2
MIR29B1
microRNA 29a
chr1_-_1293904 0.46 ENST00000309212.6
ENST00000342753.4
ENST00000445648.2
MXRA8
matrix-remodelling associated 8
chr15_+_68871569 0.46 ENST00000566799.1
CORO2B
coronin, actin binding protein, 2B
chrX_-_16888276 0.46 ENST00000493145.1
RBBP7
retinoblastoma binding protein 7
chr19_-_55954230 0.46 ENST00000376325.4
SHISA7
shisa family member 7
chr14_+_77647966 0.45 ENST00000554766.1
TMEM63C
transmembrane protein 63C
chr14_+_65878565 0.45 ENST00000556518.1
ENST00000557164.1
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr10_-_71169031 0.45 ENST00000373307.1
TACR2
tachykinin receptor 2
chr17_-_79791118 0.45 ENST00000576431.1
ENST00000575061.1
ENST00000455127.2
ENST00000572645.1
ENST00000538396.1
ENST00000573478.1
FAM195B
family with sequence similarity 195, member B
chr2_+_175199674 0.44 ENST00000394967.2
SP9
Sp9 transcription factor
chr1_+_44457261 0.44 ENST00000372318.3
CCDC24
coiled-coil domain containing 24
chr7_-_6570817 0.44 ENST00000435185.1
GRID2IP
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
chr22_-_50523843 0.43 ENST00000535444.1
ENST00000431262.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr4_-_76439596 0.43 ENST00000451788.1
ENST00000512706.1
RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr19_+_58095501 0.43 ENST00000536878.2
ENST00000597850.1
ENST00000597219.1
ENST00000598689.1
ENST00000599456.1
ENST00000307468.4
ZIK1
zinc finger protein interacting with K protein 1
chr1_+_45140360 0.42 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
C1orf228
chromosome 1 open reading frame 228
chr5_+_115298165 0.41 ENST00000357872.4
AQPEP
Aminopeptidase Q
chr3_-_189839467 0.41 ENST00000426003.1
LEPREL1
leprecan-like 1
chr22_+_23235872 0.40 ENST00000390320.2
IGLJ1
immunoglobulin lambda joining 1
chr3_+_39851170 0.40 ENST00000425621.1
ENST00000396217.3
MYRIP
myosin VIIA and Rab interacting protein
chr1_+_150254936 0.39 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr12_-_6756559 0.38 ENST00000536350.1
ENST00000414226.2
ENST00000546114.1
ACRBP
acrosin binding protein
chrX_+_153524024 0.37 ENST00000369915.3
ENST00000217905.7
TKTL1
transketolase-like 1
chr19_-_55953704 0.37 ENST00000416792.1
SHISA7
shisa family member 7
chr4_+_76439665 0.37 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP6
THAP domain containing 6
chr2_-_220108309 0.36 ENST00000409640.1
GLB1L
galactosidase, beta 1-like
chr20_+_306221 0.35 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr2_-_105372203 0.34 ENST00000424321.1
AC068057.2
long intergenic non-protein coding RNA 1114
chr12_-_6756609 0.34 ENST00000229243.2
ACRBP
acrosin binding protein
chrX_-_153523462 0.33 ENST00000361930.3
ENST00000369926.1
TEX28
testis expressed 28
chr17_-_41465674 0.33 ENST00000592135.1
ENST00000587874.1
ENST00000588654.1
ENST00000592094.1
LINC00910
long intergenic non-protein coding RNA 910
chr14_-_67826538 0.32 ENST00000553687.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr19_+_37837218 0.32 ENST00000591134.1
HKR1
HKR1, GLI-Kruppel zinc finger family member
chrX_-_16888448 0.32 ENST00000468092.1
ENST00000404022.1
ENST00000380087.2
RBBP7
retinoblastoma binding protein 7
chr11_-_6440624 0.32 ENST00000311051.3
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr5_+_112227311 0.32 ENST00000391338.1
ZRSR1
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
chr19_-_19739321 0.32 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr11_+_134146635 0.30 ENST00000431683.2
GLB1L3
galactosidase, beta 1-like 3
chr22_-_42310570 0.30 ENST00000457093.1
SHISA8
shisa family member 8
chr6_+_46620676 0.30 ENST00000371347.5
ENST00000411689.2
SLC25A27
solute carrier family 25, member 27
chr8_-_65711310 0.29 ENST00000310193.3
CYP7B1
cytochrome P450, family 7, subfamily B, polypeptide 1
chr2_+_202655184 0.29 ENST00000410091.3
CDK15
cyclin-dependent kinase 15
chr5_+_179125907 0.29 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
CANX
calnexin
chr11_+_64059464 0.28 ENST00000394525.2
KCNK4
potassium channel, subfamily K, member 4
chr8_+_38089198 0.28 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
DDHD2
DDHD domain containing 2
chr19_+_45281118 0.28 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr14_-_81687197 0.28 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr1_-_147632428 0.28 ENST00000599640.1
BX842679.1
Uncharacterized protein FLJ46360
chr7_+_148959262 0.27 ENST00000434415.1
ZNF783
zinc finger family member 783
chr2_-_74648702 0.27 ENST00000518863.1
C2orf81
chromosome 2 open reading frame 81
chr4_-_135248604 0.26 ENST00000515491.1
ENST00000504728.1
ENST00000506638.1
RP11-400D2.2
RP11-400D2.2
chr4_+_113152881 0.26 ENST00000274000.5
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr2_+_201981119 0.26 ENST00000395148.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr19_-_36822551 0.24 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chr4_+_113152978 0.24 ENST00000309703.6
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr11_+_6866883 0.24 ENST00000299454.4
ENST00000379831.2
OR10A5
olfactory receptor, family 10, subfamily A, member 5
chr17_-_17109579 0.23 ENST00000321560.3
PLD6
phospholipase D family, member 6
chr7_-_53879623 0.22 ENST00000380970.2
GS1-179L18.1
GS1-179L18.1
chr18_+_11752040 0.22 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr20_+_306177 0.21 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr2_-_169769787 0.20 ENST00000451987.1
SPC25
SPC25, NDC80 kinetochore complex component
chr11_+_9595180 0.19 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr11_-_777467 0.19 ENST00000397472.2
ENST00000524550.1
ENST00000319863.8
ENST00000526325.1
ENST00000442059.2
PDDC1
Parkinson disease 7 domain containing 1
chrX_+_133594168 0.19 ENST00000298556.7
HPRT1
hypoxanthine phosphoribosyltransferase 1
chr6_+_46620705 0.19 ENST00000452689.2
SLC25A27
solute carrier family 25, member 27
chr6_-_114292449 0.18 ENST00000519065.1
HDAC2
histone deacetylase 2
chr5_+_95066823 0.18 ENST00000506817.1
ENST00000379982.3
RHOBTB3
Rho-related BTB domain containing 3
chr8_-_142012169 0.17 ENST00000517453.1
PTK2
protein tyrosine kinase 2
chr11_-_119066545 0.17 ENST00000415318.1
CCDC153
coiled-coil domain containing 153
chr5_+_115298145 0.17 ENST00000395528.2
AQPEP
Aminopeptidase Q
chr11_-_795170 0.16 ENST00000481290.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr1_+_44445549 0.16 ENST00000356836.6
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr14_-_67826486 0.15 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chrX_-_153523796 0.14 ENST00000428625.1
TEX28
testis expressed 28
chr2_+_113403434 0.14 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr4_-_52904425 0.14 ENST00000535450.1
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr13_+_80055284 0.14 ENST00000218652.7
NDFIP2
Nedd4 family interacting protein 2
chr21_-_33985127 0.14 ENST00000290155.3
C21orf59
chromosome 21 open reading frame 59
chr6_-_74161977 0.14 ENST00000370318.1
ENST00000370315.3
MB21D1
Mab-21 domain containing 1
chr22_+_41777927 0.13 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr14_+_90422239 0.12 ENST00000393452.3
ENST00000554180.1
ENST00000393454.2
ENST00000553617.1
ENST00000335725.4
ENST00000357382.3
ENST00000556867.1
ENST00000553527.1
TDP1
tyrosyl-DNA phosphodiesterase 1
chr15_+_91498089 0.12 ENST00000394258.2
ENST00000555155.1
RCCD1
RCC1 domain containing 1
chr10_-_131309525 0.12 ENST00000601031.1
AL355531.2
Uncharacterized protein
chr17_+_46048471 0.12 ENST00000578018.1
ENST00000579175.1
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr14_+_23025534 0.12 ENST00000557595.1
AE000662.92
Uncharacterized protein
chr6_-_114292284 0.11 ENST00000520895.1
ENST00000521163.1
ENST00000524334.1
ENST00000368632.2
ENST00000398283.2
HDAC2
histone deacetylase 2
chr17_-_43025005 0.11 ENST00000587309.1
ENST00000593135.1
ENST00000339151.4
KIF18B
kinesin family member 18B
chr22_+_30752606 0.11 ENST00000399824.2
ENST00000405659.1
ENST00000338306.3
CCDC157
coiled-coil domain containing 157
chr11_+_537494 0.11 ENST00000270115.7
LRRC56
leucine rich repeat containing 56
chr11_-_124267264 0.11 ENST00000354597.3
OR8B3
olfactory receptor, family 8, subfamily B, member 3
chr1_-_31661000 0.11 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr4_+_76439095 0.10 ENST00000506261.1
THAP6
THAP domain containing 6
chr9_-_139658965 0.10 ENST00000316144.5
LCN15
lipocalin 15
chr11_+_74951948 0.10 ENST00000562197.2
TPBGL
trophoblast glycoprotein-like
chr17_+_46048497 0.10 ENST00000583352.1
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr22_-_25170683 0.10 ENST00000332271.5
PIWIL3
piwi-like RNA-mediated gene silencing 3
chr19_+_8740061 0.10 ENST00000593792.1
CTD-2586B10.1
CTD-2586B10.1

Network of associatons between targets according to the STRING database.

First level regulatory network of HES7_HES5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 10.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.9 3.7 GO:0036071 N-glycan fucosylation(GO:0036071)
0.6 1.9 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.5 5.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.5 3.2 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.5 1.5 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.4 8.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.3 2.6 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.3 0.9 GO:0040040 thermosensory behavior(GO:0040040)
0.3 0.9 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.3 1.9 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.3 4.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.3 0.8 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.2 0.5 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 3.6 GO:0015671 oxygen transport(GO:0015671)
0.1 1.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.3 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.5 GO:0035106 negative regulation of luteinizing hormone secretion(GO:0033685) operant conditioning(GO:0035106)
0.1 1.6 GO:0015816 glycine transport(GO:0015816)
0.1 1.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 2.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.3 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.2 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 2.6 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.3 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.8 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 1.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.6 GO:0007028 cytoplasm organization(GO:0007028)
0.0 1.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.4 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 3.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 1.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.3 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.9 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.4 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.5 GO:0045141 meiotic telomere clustering(GO:0045141)
0.0 0.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.5 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.2 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.7 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.0 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.4 GO:0060292 long term synaptic depression(GO:0060292)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.3 GO:0044308 axonal spine(GO:0044308)
0.5 1.8 GO:0030849 autosome(GO:0030849)
0.2 0.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.8 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 3.2 GO:0005922 connexon complex(GO:0005922)
0.1 8.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.1 GO:0033391 chromatoid body(GO:0033391)
0.1 2.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 1.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 8.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 3.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 3.5 GO:0043204 perikaryon(GO:0043204)
0.0 4.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 12.6 GO:0005874 microtubule(GO:0005874)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 1.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.4 GO:0005901 caveola(GO:0005901)
0.0 1.3 GO:0042734 presynaptic membrane(GO:0042734)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.5 5.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.5 3.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.5 1.5 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.3 0.9 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.3 4.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 8.0 GO:0031005 filamin binding(GO:0031005)
0.2 2.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.7 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.2 1.5 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2 3.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 4.6 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.7 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.5 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 1.9 GO:0005113 patched binding(GO:0005113)
0.1 1.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.3 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.4 GO:0004802 transketolase activity(GO:0004802)
0.1 0.5 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.6 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.5 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.6 GO:0071253 connexin binding(GO:0071253)
0.1 2.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 1.3 GO:0047617 very long-chain fatty acid-CoA ligase activity(GO:0031957) acyl-CoA hydrolase activity(GO:0047617)
0.1 0.7 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 1.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 9.4 GO:0015631 tubulin binding(GO:0015631)
0.0 0.5 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 6.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.6 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 2.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.0 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 5.3 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 3.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 3.9 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 3.1 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis