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Illumina Body Map 2, young vs old

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Results for HINFP1

Z-value: 0.30

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Transcription factors associated with HINFP1

Gene Symbol Gene ID Gene Info

Activity profile of HINFP1 motif

Sorted Z-values of HINFP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_119249819 1.81 ENST00000217999.2
RHOXF1
Rhox homeobox family, member 1
chrX_-_125686784 1.51 ENST00000371126.1
DCAF12L1
DDB1 and CUL4 associated factor 12-like 1
chr16_+_610407 1.15 ENST00000409413.3
C16orf11
chromosome 16 open reading frame 11
chr10_-_50970322 1.11 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr10_-_50970382 1.10 ENST00000419399.1
ENST00000432695.1
OGDHL
oxoglutarate dehydrogenase-like
chr1_-_62785054 0.89 ENST00000371153.4
KANK4
KN motif and ankyrin repeat domains 4
chr1_-_62784935 0.83 ENST00000354381.3
KANK4
KN motif and ankyrin repeat domains 4
chr1_+_210111534 0.77 ENST00000422431.1
ENST00000534859.1
ENST00000399639.2
ENST00000537238.1
SYT14
synaptotagmin XIV
chr6_-_168720382 0.64 ENST00000610183.1
ENST00000607983.1
ENST00000366795.3
DACT2
dishevelled-binding antagonist of beta-catenin 2
chr19_+_4198072 0.64 ENST00000262970.5
ANKRD24
ankyrin repeat domain 24
chr5_+_154393260 0.63 ENST00000435029.4
KIF4B
kinesin family member 4B
chr1_-_42921915 0.61 ENST00000372565.3
ENST00000433602.2
ZMYND12
zinc finger, MYND-type containing 12
chr21_+_35445827 0.59 ENST00000608209.1
ENST00000381151.3
SLC5A3
SLC5A3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr1_+_210111570 0.56 ENST00000367019.1
ENST00000472886.1
SYT14
synaptotagmin XIV
chr2_-_234763105 0.55 ENST00000454020.1
HJURP
Holliday junction recognition protein
chr15_-_58357932 0.46 ENST00000347587.3
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr20_+_35974532 0.44 ENST00000373578.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr4_+_2043689 0.44 ENST00000382878.3
ENST00000409248.4
C4orf48
chromosome 4 open reading frame 48
chr19_+_1524072 0.44 ENST00000454744.2
PLK5
polo-like kinase 5
chr2_-_234763147 0.42 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
HJURP
Holliday junction recognition protein
chr15_-_58357866 0.38 ENST00000537372.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr4_+_2043777 0.38 ENST00000409860.1
C4orf48
chromosome 4 open reading frame 48
chr9_-_33264676 0.29 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr14_+_73704201 0.26 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr21_+_35445811 0.25 ENST00000399312.2
MRPS6
mitochondrial ribosomal protein S6
chr3_-_196045127 0.24 ENST00000325318.5
TCTEX1D2
Tctex1 domain containing 2
chr6_-_168720425 0.23 ENST00000366796.3
DACT2
dishevelled-binding antagonist of beta-catenin 2
chr2_-_96811170 0.23 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr14_+_45366518 0.21 ENST00000557112.1
C14orf28
chromosome 14 open reading frame 28
chr1_+_109102652 0.20 ENST00000370035.3
ENST00000405454.1
FAM102B
family with sequence similarity 102, member B
chr11_+_637246 0.17 ENST00000176183.5
DRD4
dopamine receptor D4
chr10_+_121578211 0.16 ENST00000369080.3
INPP5F
inositol polyphosphate-5-phosphatase F
chr1_+_43232913 0.15 ENST00000372525.5
ENST00000536543.1
C1orf50
chromosome 1 open reading frame 50
chr1_-_43232649 0.14 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
LEPRE1
leucine proline-enriched proteoglycan (leprecan) 1
chr10_-_75634260 0.14 ENST00000372765.1
ENST00000351293.3
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr15_-_32162833 0.11 ENST00000560598.1
OTUD7A
OTU domain containing 7A
chr14_+_55033815 0.10 ENST00000554335.1
SAMD4A
sterile alpha motif domain containing 4A
chr10_-_75634326 0.09 ENST00000322635.3
ENST00000444854.2
ENST00000423381.1
ENST00000322680.3
ENST00000394762.2
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr7_+_1609765 0.08 ENST00000437964.1
ENST00000533935.1
ENST00000532358.1
ENST00000524978.1
PSMG3-AS1
PSMG3 antisense RNA 1 (head to head)
chr1_-_222886526 0.07 ENST00000541237.1
AIDA
axin interactor, dorsalization associated
chr7_-_1609591 0.03 ENST00000288607.2
ENST00000404674.3
PSMG3
proteasome (prosome, macropain) assembly chaperone 3
chr1_-_94147385 0.01 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3

Network of associatons between targets according to the STRING database.

First level regulatory network of HINFP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:1900108 inner medullary collecting duct development(GO:0072061) negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.4 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.6 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.8 GO:0035799 ureter maturation(GO:0035799)
0.0 2.2 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0051944 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 1.0 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.4 GO:0002347 response to tumor cell(GO:0002347)
0.0 1.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.2 GO:0031021 interphase microtubule organizing center(GO:0031021)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 0.6 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.1 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.8 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST STAT3 PATHWAY STAT3 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere