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Illumina Body Map 2, young vs old

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Results for HOXA10_HOXB9

Z-value: 0.14

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Transcription factors associated with HOXA10_HOXB9

Gene Symbol Gene ID Gene Info
HOXA10
ENSG00000253293.3 homeobox A10
HOXB9
ENSG00000170689.8 homeobox B9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB9hg19_v2_chr17_-_46703826_467038450.183.2e-01Click!
HOXA10hg19_v2_chr7_-_27213893_27213954-0.163.9e-01Click!

Activity profile of HOXA10_HOXB9 motif

Sorted Z-values of HOXA10_HOXB9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_73848531 3.74 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr7_+_128784712 3.67 ENST00000289407.4
TSPAN33
tetraspanin 33
chr10_-_73848086 3.52 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr4_+_68424434 2.69 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr13_+_108921977 2.28 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr12_+_70219052 2.16 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr14_+_22631122 1.84 ENST00000390458.3
TRAV29DV5
T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene)
chr13_+_24844979 1.78 ENST00000454083.1
SPATA13
spermatogenesis associated 13
chr15_-_55541227 1.75 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr9_+_95736758 1.65 ENST00000337352.6
FGD3
FYVE, RhoGEF and PH domain containing 3
chr8_-_71157595 1.63 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr13_+_24844857 1.59 ENST00000409126.1
ENST00000343003.6
SPATA13
spermatogenesis associated 13
chr13_+_108922228 1.47 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr13_-_103719196 1.44 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr14_+_22433675 1.42 ENST00000390442.3
TRAV12-3
T cell receptor alpha variable 12-3
chr2_+_185463093 1.41 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr9_+_44868935 1.41 ENST00000448436.2
RP11-160N1.10
RP11-160N1.10
chr3_-_58196688 1.41 ENST00000486455.1
DNASE1L3
deoxyribonuclease I-like 3
chr15_+_48483736 1.37 ENST00000417307.2
ENST00000559641.1
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr4_-_71532207 1.29 ENST00000543780.1
ENST00000391614.3
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr16_+_66613351 1.27 ENST00000379486.2
ENST00000268595.2
CMTM2
CKLF-like MARVEL transmembrane domain containing 2
chr11_-_13517565 1.26 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr4_-_48683188 1.26 ENST00000505759.1
FRYL
FRY-like
chr4_+_155484155 1.25 ENST00000509493.1
FGB
fibrinogen beta chain
chr1_+_241695424 1.23 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr14_+_22356029 1.22 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr9_-_104198042 1.21 ENST00000374855.4
ALDOB
aldolase B, fructose-bisphosphate
chr1_+_192127578 1.21 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr4_+_155484103 1.20 ENST00000302068.4
FGB
fibrinogen beta chain
chr14_+_22675388 1.18 ENST00000390461.2
TRAV34
T cell receptor alpha variable 34
chr4_-_71532668 1.14 ENST00000510437.1
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_-_71532601 1.13 ENST00000510614.1
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr12_-_90049878 1.11 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr12_-_94673956 1.10 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr17_-_39646116 1.08 ENST00000328119.6
KRT36
keratin 36
chr1_+_84630645 1.04 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_181988560 1.02 ENST00000424170.1
ENST00000435411.1
AC104820.2
AC104820.2
chr12_-_90049828 1.02 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr13_-_47012325 1.02 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr4_-_36245561 1.01 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_39944025 1.01 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr22_-_23922448 0.95 ENST00000438703.1
ENST00000330377.2
IGLL1
immunoglobulin lambda-like polypeptide 1
chr2_-_216878305 0.95 ENST00000263268.6
MREG
melanoregulin
chr7_-_143105941 0.94 ENST00000275815.3
EPHA1
EPH receptor A1
chr4_-_71532339 0.94 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr1_-_186430222 0.93 ENST00000391997.2
PDC
phosducin
chr21_+_34398153 0.93 ENST00000382357.3
ENST00000430860.1
ENST00000333337.3
OLIG2
oligodendrocyte lineage transcription factor 2
chr11_-_26744908 0.92 ENST00000533617.1
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr10_+_90521163 0.91 ENST00000404459.1
LIPN
lipase, family member N
chr6_+_6588316 0.89 ENST00000379953.2
LY86
lymphocyte antigen 86
chr13_+_28813645 0.89 ENST00000282391.5
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr1_+_84630574 0.88 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr19_+_48497962 0.88 ENST00000596043.1
ENST00000597519.1
ELSPBP1
epididymal sperm binding protein 1
chr16_-_21663919 0.86 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr10_+_94451574 0.86 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr15_+_78830023 0.86 ENST00000599596.1
AC027228.1
HCG2005369; Uncharacterized protein
chr1_-_86848760 0.85 ENST00000460698.2
ODF2L
outer dense fiber of sperm tails 2-like
chr19_-_19626838 0.85 ENST00000360913.3
TSSK6
testis-specific serine kinase 6
chr22_-_23922410 0.85 ENST00000249053.3
IGLL1
immunoglobulin lambda-like polypeptide 1
chr12_+_54892550 0.84 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr4_-_72649763 0.83 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr15_-_22448819 0.82 ENST00000604066.1
IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr1_+_154401791 0.81 ENST00000476006.1
IL6R
interleukin 6 receptor
chr2_-_158182322 0.80 ENST00000420719.2
ENST00000409216.1
ERMN
ermin, ERM-like protein
chr4_-_170897045 0.80 ENST00000508313.1
RP11-205M3.3
RP11-205M3.3
chr12_+_8608522 0.79 ENST00000382073.3
CLEC6A
C-type lectin domain family 6, member A
chr8_-_81083890 0.79 ENST00000518937.1
TPD52
tumor protein D52
chr16_-_21663950 0.79 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr19_+_48497901 0.78 ENST00000339841.2
ELSPBP1
epididymal sperm binding protein 1
chr1_+_151739131 0.77 ENST00000400999.1
OAZ3
ornithine decarboxylase antizyme 3
chr9_+_82188077 0.75 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr4_-_57522598 0.74 ENST00000553379.2
HOPX
HOP homeobox
chr1_+_151735431 0.74 ENST00000321531.5
ENST00000315067.8
OAZ3
ornithine decarboxylase antizyme 3
chr4_-_57522673 0.73 ENST00000381255.3
ENST00000317745.7
ENST00000555760.2
ENST00000556614.2
HOPX
HOP homeobox
chr4_+_36283213 0.72 ENST00000357504.3
DTHD1
death domain containing 1
chr4_+_71248795 0.71 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chr14_+_22972735 0.71 ENST00000390500.1
TRAJ37
T cell receptor alpha joining 37
chr14_+_22976633 0.71 ENST00000390503.1
TRAJ34
T cell receptor alpha joining 34
chr4_-_57547870 0.71 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX
HOP homeobox
chr1_+_12524965 0.70 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr19_-_10420459 0.70 ENST00000403352.1
ENST00000403903.3
ZGLP1
zinc finger, GATA-like protein 1
chr12_+_116985896 0.70 ENST00000547114.1
RP11-809C9.2
RP11-809C9.2
chr15_+_40886439 0.69 ENST00000532056.1
ENST00000399668.2
CASC5
cancer susceptibility candidate 5
chr14_-_60097297 0.67 ENST00000395090.1
RTN1
reticulon 1
chr6_-_87804815 0.67 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr15_+_40886199 0.67 ENST00000346991.5
ENST00000528975.1
ENST00000527044.1
CASC5
cancer susceptibility candidate 5
chr1_+_244515930 0.65 ENST00000366537.1
ENST00000308105.4
C1orf100
chromosome 1 open reading frame 100
chr12_+_90313394 0.65 ENST00000549551.1
RP11-654D12.2
RP11-654D12.2
chr1_+_241695670 0.65 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr12_+_4130143 0.64 ENST00000543206.1
RP11-320N7.2
RP11-320N7.2
chr15_+_54793169 0.64 ENST00000559093.1
UNC13C
unc-13 homolog C (C. elegans)
chr18_-_5396271 0.64 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr10_-_99030395 0.63 ENST00000355366.5
ENST00000371027.1
ARHGAP19
Rho GTPase activating protein 19
chr2_+_90198535 0.63 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr20_+_3767547 0.63 ENST00000344256.6
ENST00000379598.5
CDC25B
cell division cycle 25B
chr14_-_68000442 0.61 ENST00000554278.1
TMEM229B
transmembrane protein 229B
chr18_+_3252265 0.60 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr7_+_135710494 0.59 ENST00000440744.2
AC024084.1
AC024084.1
chr8_+_92114060 0.58 ENST00000518304.1
LRRC69
leucine rich repeat containing 69
chr9_-_28670283 0.58 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr11_+_63606373 0.58 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2
MAP/microtubule affinity-regulating kinase 2
chr7_+_35756092 0.56 ENST00000458087.3
AC018647.3
AC018647.3
chr2_+_28718921 0.55 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
PLB1
phospholipase B1
chr11_+_61717279 0.55 ENST00000378043.4
BEST1
bestrophin 1
chr18_+_55024383 0.55 ENST00000586360.1
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr14_-_60097524 0.54 ENST00000342503.4
RTN1
reticulon 1
chr6_-_10115007 0.54 ENST00000485268.1
OFCC1
orofacial cleft 1 candidate 1
chrX_+_48620147 0.54 ENST00000303227.6
GLOD5
glyoxalase domain containing 5
chr20_-_7921090 0.53 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr10_+_47658234 0.53 ENST00000447511.2
ENST00000537271.1
ANTXRL
anthrax toxin receptor-like
chr6_+_46761118 0.53 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr20_+_10015678 0.53 ENST00000378392.1
ENST00000378380.3
ANKEF1
ankyrin repeat and EF-hand domain containing 1
chr11_+_61717336 0.52 ENST00000378042.3
BEST1
bestrophin 1
chr2_+_197577841 0.52 ENST00000409270.1
CCDC150
coiled-coil domain containing 150
chr7_+_35756400 0.52 ENST00000585952.1
AC018647.3
AC018647.3
chr7_-_142232071 0.51 ENST00000390364.3
TRBV10-1
T cell receptor beta variable 10-1(gene/pseudogene)
chr9_+_2029019 0.51 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_82187487 0.51 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chrX_+_144908928 0.51 ENST00000408967.2
TMEM257
transmembrane protein 257
chrX_+_41548259 0.51 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chr11_-_104905840 0.51 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr9_+_103947311 0.50 ENST00000395056.2
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr17_-_29624343 0.50 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr2_+_113885138 0.50 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr8_+_66955648 0.47 ENST00000522619.1
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr17_-_38821373 0.47 ENST00000394052.3
KRT222
keratin 222
chr17_+_61151306 0.47 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr12_+_25205446 0.47 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr15_+_66797455 0.47 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr5_-_36001108 0.47 ENST00000333811.4
UGT3A1
UDP glycosyltransferase 3 family, polypeptide A1
chr4_+_187187098 0.46 ENST00000403665.2
ENST00000264692.4
F11
coagulation factor XI
chr11_-_5537920 0.46 ENST00000380184.1
UBQLNL
ubiquilin-like
chr2_-_158182105 0.45 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr7_+_18536090 0.45 ENST00000441986.1
HDAC9
histone deacetylase 9
chr11_+_10471836 0.44 ENST00000444303.2
AMPD3
adenosine monophosphate deaminase 3
chr21_+_30503282 0.44 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr13_+_24844819 0.44 ENST00000399949.2
SPATA13
spermatogenesis associated 13
chr9_-_73736511 0.44 ENST00000377110.3
ENST00000377111.2
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr11_-_104972158 0.44 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr18_+_22040620 0.43 ENST00000426880.2
HRH4
histamine receptor H4
chr8_-_81083731 0.43 ENST00000379096.5
TPD52
tumor protein D52
chr10_+_26505179 0.43 ENST00000376261.3
GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr6_+_158733692 0.43 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr9_+_82187630 0.43 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_-_7913089 0.43 ENST00000361696.5
UTS2
urotensin 2
chr11_+_115498761 0.42 ENST00000424313.2
AP000997.1
AP000997.1
chr2_-_40657397 0.42 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr12_+_25205628 0.41 ENST00000554942.1
LRMP
lymphoid-restricted membrane protein
chr1_-_155880672 0.41 ENST00000609492.1
ENST00000368322.3
RIT1
Ras-like without CAAX 1
chr9_-_20382446 0.41 ENST00000380321.1
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr11_-_92930556 0.40 ENST00000529184.1
SLC36A4
solute carrier family 36 (proton/amino acid symporter), member 4
chr12_+_25205666 0.39 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr9_-_133814455 0.39 ENST00000448616.1
FIBCD1
fibrinogen C domain containing 1
chr16_+_72090053 0.39 ENST00000576168.2
ENST00000567185.3
ENST00000567612.2
HP
haptoglobin
chr19_-_19626351 0.38 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr2_+_38177575 0.38 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2
regulator of microtubule dynamics 2
chr1_-_207143802 0.38 ENST00000324852.4
ENST00000400962.3
FCAMR
Fc receptor, IgA, IgM, high affinity
chr17_-_10560619 0.38 ENST00000583535.1
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic
chr12_+_25205155 0.38 ENST00000550945.1
LRMP
lymphoid-restricted membrane protein
chr15_+_66797627 0.38 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr8_+_91233711 0.37 ENST00000523283.1
ENST00000517400.1
LINC00534
long intergenic non-protein coding RNA 534
chr10_-_73497581 0.37 ENST00000398786.2
C10orf105
chromosome 10 open reading frame 105
chr7_-_77427676 0.37 ENST00000257663.3
TMEM60
transmembrane protein 60
chr14_-_57272366 0.37 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr16_+_12070567 0.37 ENST00000566228.1
SNX29
sorting nexin 29
chr2_+_172309634 0.37 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr17_-_73663245 0.36 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chr18_+_3252206 0.36 ENST00000578562.2
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr7_-_142143973 0.35 ENST00000390373.2
TRBV6-7
T cell receptor beta variable 6-7 (non-functional)
chr4_+_88754113 0.35 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr2_+_38177620 0.35 ENST00000402091.3
RMDN2
regulator of microtubule dynamics 2
chr3_-_138048682 0.34 ENST00000383180.2
NME9
NME/NM23 family member 9
chr2_+_112939365 0.34 ENST00000272559.4
FBLN7
fibulin 7
chr19_+_3185910 0.34 ENST00000588428.1
NCLN
nicalin
chr1_-_39339777 0.34 ENST00000397572.2
MYCBP
MYC binding protein
chr4_+_71263599 0.33 ENST00000399575.2
PROL1
proline rich, lacrimal 1
chr2_+_234668894 0.33 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
UGT1A8
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr5_+_158737824 0.33 ENST00000521472.1
AC008697.1
AC008697.1
chr4_-_123377880 0.33 ENST00000226730.4
IL2
interleukin 2
chr20_+_42984330 0.33 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr14_-_106453155 0.33 ENST00000390594.2
IGHV1-2
immunoglobulin heavy variable 1-2
chr1_+_116654376 0.33 ENST00000369500.3
MAB21L3
mab-21-like 3 (C. elegans)
chr17_-_73663168 0.33 ENST00000578201.1
ENST00000423245.2
RECQL5
RecQ protein-like 5
chr5_+_126984710 0.33 ENST00000379445.3
CTXN3
cortexin 3
chr12_+_25205568 0.32 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr5_+_43121698 0.32 ENST00000505606.2
ENST00000509634.1
ENST00000509341.1
ZNF131
zinc finger protein 131
chr4_+_70916119 0.32 ENST00000246896.3
ENST00000511674.1
HTN1
histatin 1
chr5_-_159766528 0.32 ENST00000505287.2
CCNJL
cyclin J-like
chr17_+_57807062 0.32 ENST00000587259.1
VMP1
vacuole membrane protein 1
chr6_+_32812568 0.32 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr5_-_20575959 0.31 ENST00000507958.1
CDH18
cadherin 18, type 2
chr1_-_143767881 0.31 ENST00000419275.1
PPIAL4G
peptidylprolyl isomerase A (cyclophilin A)-like 4G
chr2_+_215275771 0.31 ENST00000312504.5
ENST00000427124.1
VWC2L
von Willebrand factor C domain containing protein 2-like
chr12_-_81992111 0.31 ENST00000443686.3
ENST00000407050.4
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr12_+_40549984 0.31 ENST00000457989.1
AC079630.2
AC079630.2
chr11_+_120973375 0.31 ENST00000264037.2
TECTA
tectorin alpha
chr3_+_138340067 0.30 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr3_+_185046676 0.30 ENST00000428617.1
ENST00000443863.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr10_-_115614127 0.30 ENST00000369305.1
DCLRE1A
DNA cross-link repair 1A
chr1_-_226926864 0.30 ENST00000429204.1
ENST00000366784.1
ITPKB
inositol-trisphosphate 3-kinase B

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA10_HOXB9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:1903980 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)
0.7 3.7 GO:0002636 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.5 1.6 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.4 1.3 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3 0.9 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 7.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 1.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.3 0.9 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.3 1.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.3 1.8 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 2.1 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.2 0.9 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.8 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 0.8 GO:0002384 hepatic immune response(GO:0002384)
0.2 1.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 1.9 GO:0097338 response to clozapine(GO:0097338)
0.2 0.9 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 2.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.5 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.1 0.4 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.7 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.7 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.4 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 0.3 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 2.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 1.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.3 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.1 1.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.4 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 0.5 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.3 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.2 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.1 0.9 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.4 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.1 0.1 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.1 0.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.6 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.3 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:2000295 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of hydrogen peroxide catabolic process(GO:2000295) positive regulation of peroxidase activity(GO:2000470)
0.0 0.6 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.6 GO:0007144 female meiosis I(GO:0007144)
0.0 1.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.4 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.4 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.3 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 1.0 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.1 GO:0071336 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 4.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 2.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.2 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 1.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.3 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.8 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.3 GO:0019530 taurine metabolic process(GO:0019530)
0.0 1.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.9 GO:0032402 melanosome transport(GO:0032402)
0.0 0.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.7 GO:0048599 oocyte development(GO:0048599)
0.0 0.0 GO:1990637 response to prolactin(GO:1990637) regulation of ovarian follicle development(GO:2000354)
0.0 0.1 GO:0046449 creatinine metabolic process(GO:0046449)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.3 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.3 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 2.0 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 1.7 GO:0006903 vesicle targeting(GO:0006903)
0.0 3.7 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 0.4 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.9 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.9 GO:0031251 PAN complex(GO:0031251)
0.2 0.8 GO:1990423 RZZ complex(GO:1990423)
0.2 2.5 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.2 GO:0097179 protease inhibitor complex(GO:0097179)
0.2 0.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.4 GO:0033269 internode region of axon(GO:0033269)
0.1 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 2.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.6 GO:0044305 calyx of Held(GO:0044305)
0.1 0.5 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 2.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.8 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.6 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 1.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.4 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077) clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 3.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.3 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 3.0 GO:0072562 blood microparticle(GO:0072562)
0.0 1.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.7 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.3 2.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.3 1.6 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.3 1.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.3 0.8 GO:1902271 D3 vitamins binding(GO:1902271)
0.3 0.8 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.2 1.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 5.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 0.5 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.2 0.5 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.2 0.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.5 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.6 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.7 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 3.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 4.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.3 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.4 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.5 GO:0050700 CARD domain binding(GO:0050700)
0.1 2.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 1.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 1.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.0 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.4 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.0 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.0 2.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0015265 urea channel activity(GO:0015265)
0.0 0.2 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.6 GO:0008061 chitin binding(GO:0008061)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 3.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 2.5 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 1.1 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.8 ST STAT3 PATHWAY STAT3 Pathway
0.0 3.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.9 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 2.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.7 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling