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Illumina Body Map 2, young vs old

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Results for HOXA13

Z-value: 0.04

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Transcription factors associated with HOXA13

Gene Symbol Gene ID Gene Info
ENSG00000106031.6 homeobox A13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA13hg19_v2_chr7_-_27239703_272397250.522.1e-03Click!

Activity profile of HOXA13 motif

Sorted Z-values of HOXA13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_189839046 4.70 ENST00000304636.3
ENST00000317840.5
collagen, type III, alpha 1
chr8_-_86290333 4.56 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
carbonic anhydrase I
chr10_+_24738355 4.29 ENST00000307544.6
KIAA1217
chr1_+_43766642 4.06 ENST00000372476.3
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr15_-_58571445 3.36 ENST00000558231.1
aldehyde dehydrogenase 1 family, member A2
chr4_+_70796784 3.18 ENST00000246891.4
ENST00000444405.3
casein alpha s1
chr1_-_178838404 3.12 ENST00000444255.1
angiopoietin-like 1
chr14_-_92414294 3.11 ENST00000554468.1
fibulin 5
chr4_-_87770416 3.02 ENST00000273905.6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr1_+_43766668 3.01 ENST00000441333.2
ENST00000538015.1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr6_+_19837592 2.92 ENST00000378700.3
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr10_-_13544945 2.90 ENST00000378605.3
ENST00000341083.3
BEN domain containing 7
chr11_-_10590238 2.89 ENST00000256178.3
lymphatic vessel endothelial hyaluronan receptor 1
chr1_+_47533160 2.84 ENST00000334194.3
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr6_+_88117683 2.65 ENST00000369562.4
UPF0704 protein C6orf165
chr7_-_27196267 2.60 ENST00000242159.3
homeobox A7
chr19_+_16999654 2.59 ENST00000248076.3
coagulation factor II (thrombin) receptor-like 3
chr14_-_92414055 2.50 ENST00000342058.4
fibulin 5
chr7_-_16921601 2.39 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
anterior gradient 3
chr7_-_27224795 2.39 ENST00000006015.3
homeobox A11
chr16_+_82090028 2.30 ENST00000568090.1
hydroxysteroid (17-beta) dehydrogenase 2
chr13_-_51101468 2.29 ENST00000428276.1
RP11-175B12.2
chr10_+_118187379 2.25 ENST00000369230.3
pancreatic lipase-related protein 3
chr20_+_55204351 2.25 ENST00000201031.2
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr14_-_60952739 2.22 ENST00000555476.1
ENST00000321731.3
chromosome 14 open reading frame 39
chr17_-_46688334 2.22 ENST00000239165.7
homeobox B7
chr4_+_128702969 2.12 ENST00000508776.1
ENST00000439123.2
heat shock 70kDa protein 4-like
chr6_+_121756809 2.01 ENST00000282561.3
gap junction protein, alpha 1, 43kDa
chr4_-_101111615 2.00 ENST00000273990.2
DNA-damage-inducible transcript 4-like
chr3_-_149093499 1.99 ENST00000472441.1
transmembrane 4 L six family member 1
chr3_-_100712352 1.99 ENST00000471714.1
ENST00000284322.5
ABI family, member 3 (NESH) binding protein
chr1_+_13910194 1.94 ENST00000376057.4
ENST00000510906.1
podoplanin
chr2_-_118943930 1.94 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
chr12_-_53074182 1.92 ENST00000252244.3
keratin 1
chr1_+_166958346 1.87 ENST00000367872.4
maelstrom spermatogenic transposon silencer
chr15_-_99789736 1.84 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
tetratricopeptide repeat domain 23
chr3_+_50211240 1.82 ENST00000420831.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr11_-_10590118 1.77 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr8_-_93029865 1.76 ENST00000422361.2
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_51895621 1.75 ENST00000333127.3
IQ motif containing F2
chr19_-_51340469 1.73 ENST00000326856.4
kallikrein-related peptidase 15
chr12_-_53207842 1.72 ENST00000458244.2
keratin 4
chr3_+_132316081 1.68 ENST00000249887.2
atypical chemokine receptor 4
chr12_-_91539918 1.64 ENST00000548218.1
decorin
chr4_+_15341442 1.64 ENST00000397700.2
ENST00000295297.4
C1q and tumor necrosis factor related protein 7
chr11_+_101983176 1.64 ENST00000524575.1
Yes-associated protein 1
chr1_-_147245445 1.61 ENST00000430508.1
gap junction protein, alpha 5, 40kDa
chr8_+_143781513 1.60 ENST00000292430.6
ENST00000561179.1
ENST00000518841.1
ENST00000519387.1
lymphocyte antigen 6 complex, locus K
chr8_-_95274536 1.60 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr18_+_31185530 1.58 ENST00000586327.1
additional sex combs like 3 (Drosophila)
chr7_-_27169801 1.57 ENST00000511914.1
homeobox A4
chr8_+_133879193 1.57 ENST00000377869.1
ENST00000220616.4
thyroglobulin
chr1_-_46642154 1.54 ENST00000540385.1
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr14_-_80678512 1.51 ENST00000553968.1
deiodinase, iodothyronine, type II
chr4_+_54243917 1.51 ENST00000507166.1
factor interacting with PAPOLA and CPSF1
chr4_+_42399856 1.51 ENST00000319234.4
shisa family member 3
chr12_+_12878829 1.49 ENST00000326765.6
apolipoprotein L domain containing 1
chr12_-_102874102 1.45 ENST00000392905.2
insulin-like growth factor 1 (somatomedin C)
chr17_+_77030267 1.42 ENST00000581774.1
C1q and tumor necrosis factor related protein 1
chr2_+_192109911 1.41 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
myosin IB
chr3_-_99569821 1.36 ENST00000487087.1
filamin A interacting protein 1-like
chr11_+_113185778 1.34 ENST00000524580.2
tetratricopeptide repeat domain 12
chr17_-_17480779 1.34 ENST00000395782.1
phosphatidylethanolamine N-methyltransferase
chr8_+_35649365 1.31 ENST00000437887.1
Uncharacterized protein
chr3_-_126373929 1.30 ENST00000523403.1
ENST00000524230.2
thioredoxin reductase 3
chr7_-_73256838 1.28 ENST00000297873.4
Williams Beuren syndrome chromosome region 27
chr3_-_51909600 1.28 ENST00000446461.1
IQ motif containing F5
chr2_-_23747214 1.25 ENST00000430988.1
Uncharacterized protein
chr1_+_78383813 1.24 ENST00000342754.5
nexilin (F actin binding protein)
chr2_+_207804278 1.24 ENST00000272852.3
carboxypeptidase O
chr7_+_23749945 1.23 ENST00000354639.3
ENST00000531170.1
ENST00000444333.2
ENST00000428484.1
serine/threonine kinase 31
chr12_+_120105558 1.20 ENST00000229328.5
ENST00000541640.1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr15_+_59908633 1.19 ENST00000559626.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chrX_+_35816459 1.18 ENST00000399988.1
ENST00000399992.1
ENST00000399987.1
ENST00000399989.1
melanoma antigen family B, 16
chr15_-_55881135 1.16 ENST00000302000.6
pygopus family PHD finger 1
chr1_+_78511586 1.15 ENST00000370759.3
GIPC PDZ domain containing family, member 2
chr4_-_110723134 1.15 ENST00000510800.1
ENST00000512148.1
complement factor I
chr3_-_123339418 1.13 ENST00000583087.1
myosin light chain kinase
chr19_+_852291 1.13 ENST00000263621.1
elastase, neutrophil expressed
chr19_+_859654 1.12 ENST00000592860.1
complement factor D (adipsin)
chr16_+_82068585 1.12 ENST00000563491.1
hydroxysteroid (17-beta) dehydrogenase 2
chr17_-_15496722 1.11 ENST00000472534.1
CMT1A duplicated region transcript 1
chrX_+_37850026 1.11 ENST00000341016.3
chromosome X open reading frame 27
chr5_-_146781153 1.11 ENST00000520473.1
dihydropyrimidinase-like 3
chr1_+_78769549 1.10 ENST00000370758.1
prostaglandin F receptor (FP)
chr7_+_23749767 1.05 ENST00000355870.3
serine/threonine kinase 31
chr11_+_7110165 1.04 ENST00000306904.5
RNA binding motif protein, X-linked-like 2
chr3_-_123339343 1.04 ENST00000578202.1
myosin light chain kinase
chr11_+_62037622 1.04 ENST00000227918.2
ENST00000525380.1
secretoglobin, family 2A, member 2
chr11_+_26495447 1.03 ENST00000531568.1
anoctamin 3
chr3_+_108855558 1.03 ENST00000467240.1
ENST00000477643.1
ENST00000479039.1
ENST00000593799.1
RP11-59E19.1
chr17_+_55183261 1.02 ENST00000576295.1
A kinase (PRKA) anchor protein 1
chr7_+_23749894 1.01 ENST00000433467.2
serine/threonine kinase 31
chr1_+_199996733 1.01 ENST00000236914.3
nuclear receptor subfamily 5, group A, member 2
chr3_-_100712292 1.01 ENST00000495063.1
ENST00000530539.1
ABI family, member 3 (NESH) binding protein
chr7_+_80275953 1.00 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36 molecule (thrombospondin receptor)
chr19_+_50084561 0.99 ENST00000246794.5
proline rich Gla (G-carboxyglutamic acid) 2
chr7_+_80275621 0.98 ENST00000426978.1
ENST00000432207.1
CD36 molecule (thrombospondin receptor)
chr3_+_154801678 0.97 ENST00000462837.1
membrane metallo-endopeptidase
chr10_-_113943447 0.97 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
glycerol-3-phosphate acyltransferase, mitochondrial
chr16_-_54304608 0.95 ENST00000561336.1
HCG2045435; Uncharacterized protein
chr7_-_69062391 0.93 ENST00000436600.2
RP5-942I16.1
chr9_+_67977438 0.92 ENST00000456982.1
Protein LOC644249
chr1_+_152730499 0.92 ENST00000368773.1
keratinocyte proline-rich protein
chr13_-_24895566 0.92 ENST00000422229.2
protein PCOTH isoform 1
chr1_-_153085984 0.92 ENST00000468739.1
small proline-rich protein 2F
chr9_+_706842 0.91 ENST00000382293.3
KN motif and ankyrin repeat domains 1
chr7_+_23749854 0.90 ENST00000456014.2
serine/threonine kinase 31
chr1_-_204183071 0.89 ENST00000308302.3
golgi transport 1A
chr7_+_80275663 0.89 ENST00000413265.1
CD36 molecule (thrombospondin receptor)
chr6_+_148663729 0.89 ENST00000367467.3
SAM and SH3 domain containing 1
chr11_+_60995849 0.89 ENST00000537932.1
pepsinogen 4, group I (pepsinogen A)
chr7_+_80275752 0.89 ENST00000419819.2
CD36 molecule (thrombospondin receptor)
chr3_+_111578027 0.88 ENST00000431670.2
ENST00000412622.1
pleckstrin homology-like domain, family B, member 2
chr2_+_33359687 0.88 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chr20_-_44420507 0.84 ENST00000243938.4
WAP four-disulfide core domain 3
chr2_+_170366203 0.84 ENST00000284669.1
kelch-like family member 41
chr19_-_7167989 0.84 ENST00000600492.1
insulin receptor
chr7_+_23749822 0.83 ENST00000422637.1
serine/threonine kinase 31
chr9_+_6215799 0.82 ENST00000417746.2
ENST00000456383.2
interleukin 33
chr2_+_33359646 0.82 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr1_+_199996702 0.82 ENST00000367362.3
nuclear receptor subfamily 5, group A, member 2
chr19_+_48497901 0.82 ENST00000339841.2
epididymal sperm binding protein 1
chr1_+_145525015 0.81 ENST00000539363.1
ENST00000538811.1
integrin, alpha 10
chr1_+_19967014 0.81 ENST00000428975.1
neuroblastoma 1, DAN family BMP antagonist
chr3_-_112013071 0.79 ENST00000487372.1
ENST00000486574.1
ENST00000305815.5
solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
chr10_-_50970322 0.77 ENST00000374103.4
oxoglutarate dehydrogenase-like
chr1_-_209975494 0.77 ENST00000456314.1
interferon regulatory factor 6
chr12_+_26274917 0.76 ENST00000538142.1
sarcospan
chr8_-_16050214 0.76 ENST00000262101.5
macrophage scavenger receptor 1
chr15_+_74165945 0.75 ENST00000535547.2
ENST00000300504.2
ENST00000562056.1
TBC1 domain family, member 21
chr19_-_51893827 0.75 ENST00000574814.1
chromosome 19 open reading frame 84
chr14_+_24540046 0.75 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
copine VI (neuronal)
chr8_-_16050288 0.75 ENST00000350896.3
macrophage scavenger receptor 1
chr10_+_102756800 0.73 ENST00000370223.3
leucine zipper, putative tumor suppressor 2
chr1_+_202431859 0.70 ENST00000391959.3
ENST00000367270.4
protein phosphatase 1, regulatory subunit 12B
chr15_+_69373184 0.70 ENST00000558147.1
ENST00000440444.1
long intergenic non-protein coding RNA 277
chr8_+_118147498 0.70 ENST00000519688.1
ENST00000456015.2
solute carrier family 30 (zinc transporter), member 8
chr3_-_160823158 0.69 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr12_-_56367101 0.69 ENST00000549233.2
premelanosome protein
chr12_-_91546926 0.68 ENST00000550758.1
decorin
chr10_-_50143242 0.68 ENST00000298124.3
leucine rich repeat containing 18
chrX_-_33357558 0.68 ENST00000288447.4
dystrophin
chr21_-_26797019 0.67 ENST00000440205.1
long intergenic non-protein coding RNA 158
chr4_-_82136114 0.67 ENST00000395578.1
ENST00000418486.2
protein kinase, cGMP-dependent, type II
chr12_-_8693469 0.67 ENST00000545274.1
ENST00000446457.2
C-type lectin domain family 4, member E
chr4_+_94125100 0.67 ENST00000512631.1
glutamate receptor, ionotropic, delta 2
chr6_+_155334780 0.67 ENST00000538270.1
ENST00000535231.1
T-cell lymphoma invasion and metastasis 2
chr15_+_69373210 0.67 ENST00000435479.1
ENST00000559870.1
long intergenic non-protein coding RNA 277
RP11-809H16.5
chr3_-_160823040 0.66 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr4_+_69313145 0.66 ENST00000305363.4
transmembrane protease, serine 11E
chr11_+_94706804 0.66 ENST00000335080.5
lysine (K)-specific demethylase 4D
chr1_-_91182794 0.66 ENST00000370445.4
BarH-like homeobox 2
chr9_+_112887772 0.65 ENST00000259318.7
A kinase (PRKA) anchor protein 2
chr12_-_50677255 0.65 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIM domain and actin binding 1
chr5_-_124081008 0.65 ENST00000306315.5
zinc finger protein 608
chr19_-_39694894 0.64 ENST00000318438.6
syncollin
chrX_-_11284095 0.64 ENST00000303025.6
ENST00000534860.1
Rho GTPase activating protein 6
chr10_+_106028923 0.63 ENST00000338595.2
glutathione S-transferase omega 2
chr12_-_71182695 0.62 ENST00000342084.4
protein tyrosine phosphatase, receptor type, R
chr6_-_51952418 0.62 ENST00000371117.3
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr11_-_4719072 0.61 ENST00000396950.3
ENST00000532598.1
olfactory receptor, family 51, subfamily E, member 2
chr7_-_50633078 0.61 ENST00000444124.2
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr19_+_36545781 0.60 ENST00000388999.3
WD repeat domain 62
chr3_-_150996146 0.60 ENST00000494668.1
purinergic receptor P2Y, G-protein coupled, 14
chr3_+_113667354 0.59 ENST00000491556.1
zinc finger, DHHC-type containing 23
chr11_+_101785727 0.58 ENST00000263468.8
KIAA1377
chr15_+_72690614 0.58 ENST00000341689.3
ENST00000567679.1
transmembrane protein 202
chr4_-_147866960 0.57 ENST00000513335.1
tetratricopeptide repeat domain 29
chr14_+_23654525 0.57 ENST00000399910.1
ENST00000492621.1
chromosome 14 open reading frame 164
chr8_-_30706608 0.57 ENST00000256246.2
testis expressed 15
chr1_-_112106578 0.57 ENST00000369717.4
adenosine A3 receptor
chr16_-_21289627 0.57 ENST00000396023.2
ENST00000415987.2
crystallin, mu
chr12_+_121163602 0.56 ENST00000411593.2
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr12_+_51317788 0.56 ENST00000550502.1
methyltransferase like 7A
chr12_+_45609893 0.55 ENST00000320560.8
anoctamin 6
chr1_+_222886694 0.54 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BRO1 domain and CAAX motif containing
chr9_-_21305312 0.53 ENST00000259555.4
interferon, alpha 5
chr4_+_190802670 0.53 ENST00000503609.1
RP11-463J17.1
chr4_-_89978299 0.53 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
family with sequence similarity 13, member A
chr19_+_49496782 0.53 ENST00000601968.1
ENST00000596837.1
RuvB-like AAA ATPase 2
chr11_+_61015594 0.52 ENST00000451616.2
pepsinogen 5, group I (pepsinogen A)
chr4_-_159956333 0.52 ENST00000434826.2
chromosome 4 open reading frame 45
chr3_+_160117062 0.52 ENST00000497311.1
structural maintenance of chromosomes 4
chr3_+_154801312 0.51 ENST00000497890.1
membrane metallo-endopeptidase
chr8_+_94710789 0.51 ENST00000523475.1
family with sequence similarity 92, member A1
chr7_-_75401513 0.51 ENST00000005180.4
chemokine (C-C motif) ligand 26
chr3_-_160822858 0.51 ENST00000488170.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr13_-_36429763 0.51 ENST00000379893.1
doublecortin-like kinase 1
chr17_+_11501748 0.50 ENST00000262442.4
ENST00000579828.1
dynein, axonemal, heavy chain 9
chr2_+_33359473 0.50 ENST00000432635.1
latent transforming growth factor beta binding protein 1
chr18_+_61223393 0.50 ENST00000269491.1
ENST00000382768.1
serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr1_-_31845914 0.49 ENST00000373713.2
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr20_+_59654146 0.47 ENST00000441660.1
RP5-827L5.1
chr12_-_12491608 0.47 ENST00000545735.1
MANSC domain containing 1
chr7_-_91808441 0.47 ENST00000437357.1
ENST00000458448.1
leucine-rich repeats and death domain containing 1
chr6_+_151042224 0.47 ENST00000358517.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr2_+_7073174 0.46 ENST00000416587.1
ring finger protein 144A
chr3_+_129159039 0.46 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
intraflagellar transport 122 homolog (Chlamydomonas)
chr4_+_106631966 0.46 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.8 6.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.6 1.9 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.6 2.9 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.4 5.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 1.6 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 2.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.3 3.4 GO:0035799 ureter maturation(GO:0035799)
0.3 1.3 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.3 3.8 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.3 0.9 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 1.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.3 1.4 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.2 0.7 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.2 1.1 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 1.0 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.2 0.6 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.2 0.6 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.2 2.6 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.2 2.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 1.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.2 1.4 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 2.6 GO:0060155 platelet dense granule organization(GO:0060155)
0.2 0.8 GO:1990535 neuron projection maintenance(GO:1990535)
0.2 0.8 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.2 0.8 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.2 2.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.5 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 3.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 4.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.4 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 1.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 1.8 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 1.6 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 1.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 2.5 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.1 7.2 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 1.5 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 0.9 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 1.1 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 1.8 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 1.6 GO:0015705 iodide transport(GO:0015705)
0.1 0.4 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.7 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 1.5 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 0.5 GO:0035720 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.6 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 1.6 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.4 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.7 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 2.2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.3 GO:0008355 olfactory learning(GO:0008355)
0.1 1.5 GO:0042118 endothelial cell activation(GO:0042118)
0.1 1.9 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 1.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 3.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 1.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.6 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.8 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.6 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 1.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.8 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0030047 actin modification(GO:0030047)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.7 GO:0035878 nail development(GO:0035878)
0.0 0.6 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.9 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.7 GO:0035588 G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 1.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.3 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 1.0 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.1 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.8 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.2 GO:0010193 response to ozone(GO:0010193) response to L-ascorbic acid(GO:0033591)
0.0 0.3 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.0 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.0 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 1.8 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 1.3 GO:0000305 response to oxygen radical(GO:0000305)
0.0 1.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.7 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.5 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 1.6 GO:0030317 sperm motility(GO:0030317)
0.0 0.2 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.0 0.4 GO:0007350 blastoderm segmentation(GO:0007350)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.5 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.9 GO:0007099 centriole replication(GO:0007099)
0.0 0.6 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.2 GO:0046541 saliva secretion(GO:0046541)
0.0 1.7 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.6 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.2 GO:0007512 adult heart development(GO:0007512)
0.0 0.7 GO:0032438 melanosome organization(GO:0032438)
0.0 0.1 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.6 GO:0040008 regulation of growth(GO:0040008)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.3 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.8 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.5 GO:0032259 methylation(GO:0032259)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.6 GO:0071953 elastic fiber(GO:0071953)
0.5 1.9 GO:0030849 autosome(GO:0030849)
0.3 1.6 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.3 4.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 1.4 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 0.8 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 2.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 3.6 GO:0005922 connexon complex(GO:0005922)
0.1 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.4 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 1.1 GO:0097255 R2TP complex(GO:0097255)
0.1 4.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 3.0 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.7 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.9 GO:0045180 basal cortex(GO:0045180)
0.0 1.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0000796 condensin complex(GO:0000796)
0.0 1.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0000801 central element(GO:0000801)
0.0 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 2.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 5.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 1.6 GO:0051233 spindle midzone(GO:0051233)
0.0 3.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.8 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 2.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 3.2 GO:0005884 actin filament(GO:0005884)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.8 GO:0032993 protein-DNA complex(GO:0032993)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.6 4.6 GO:0004064 arylesterase activity(GO:0004064)
0.5 1.6 GO:0086079 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.5 1.9 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.4 1.3 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.4 1.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.4 2.2 GO:0050436 microfibril binding(GO:0050436)
0.4 1.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.4 2.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 3.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 2.0 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.3 2.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 1.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 4.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 2.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 3.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 1.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 0.5 GO:0070538 oleic acid binding(GO:0070538)
0.2 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.6 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 1.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.7 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 1.9 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.8 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 4.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.8 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 2.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 3.1 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.8 GO:0043559 insulin binding(GO:0043559)
0.1 0.9 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 1.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 1.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 2.1 GO:0070330 aromatase activity(GO:0070330)
0.1 1.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 1.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.8 GO:0016015 morphogen activity(GO:0016015)
0.1 7.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 6.7 GO:0005518 collagen binding(GO:0005518)
0.1 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 1.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 1.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.7 GO:0019956 chemokine binding(GO:0019956)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 7.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 2.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.7 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 1.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 4.8 GO:0004518 nuclease activity(GO:0004518)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 4.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 3.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 4.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 4.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 3.3 PID AURORA B PATHWAY Aurora B signaling
0.0 10.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 3.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 2.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 4.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 4.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 2.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 4.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 1.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 2.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 2.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 4.1 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition