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Illumina Body Map 2, young vs old
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Results for HOXC10_HOXD13
Z-value: 0.39
Motif logo
Transcription factors associated with HOXC10_HOXD13
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HOXC10
|
ENSG00000180818.4 | homeobox C10 |
|
HOXD13
|
ENSG00000128714.5 | homeobox D13 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXD13 | hg19_v2_chr2_+_176957619_176957619 | 0.64 | 7.2e-05 | Click! |
| HOXC10 | hg19_v2_chr12_+_54378923_54378970 | 0.40 | 2.4e-02 | Click! |
Activity profile of HOXC10_HOXD13 motif
Sorted Z-values of HOXC10_HOXD13 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXC10_HOXD13
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 8.6 | GO:1901876 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) |
| 2.0 | 6.1 | GO:1904237 | regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237) |
| 1.4 | 5.7 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
| 1.3 | 3.9 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 1.3 | 18.8 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 1.1 | 5.7 | GO:0099543 | retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) |
| 1.1 | 4.2 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 1.0 | 3.1 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397) |
| 1.0 | 3.0 | GO:2000276 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) |
| 1.0 | 3.9 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.9 | 2.7 | GO:0060488 | orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
| 0.8 | 0.8 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.7 | 2.0 | GO:0061033 | secretion by lung epithelial cell involved in lung growth(GO:0061033) |
| 0.7 | 2.0 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) |
| 0.7 | 2.0 | GO:0071676 | negative regulation of mononuclear cell migration(GO:0071676) |
| 0.7 | 2.6 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.7 | 22.1 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.6 | 3.1 | GO:0061032 | cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032) |
| 0.6 | 1.9 | GO:0090265 | positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) |
| 0.6 | 3.1 | GO:0003051 | angiotensin-mediated drinking behavior(GO:0003051) |
| 0.6 | 1.9 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.6 | 3.0 | GO:1990523 | bone regeneration(GO:1990523) |
| 0.6 | 1.8 | GO:0010621 | negative regulation of transcription by transcription factor localization(GO:0010621) |
| 0.6 | 3.4 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) |
| 0.6 | 2.3 | GO:0060584 | response to ozone(GO:0010193) nitric oxide transport(GO:0030185) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) |
| 0.6 | 5.1 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.5 | 4.6 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.5 | 7.2 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 0.5 | 6.6 | GO:1904321 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.5 | 2.5 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 0.5 | 2.4 | GO:1901979 | regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159) |
| 0.5 | 1.9 | GO:0002384 | hepatic immune response(GO:0002384) |
| 0.5 | 1.9 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 0.5 | 4.2 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.4 | 1.8 | GO:0060029 | convergent extension involved in organogenesis(GO:0060029) |
| 0.4 | 4.8 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
| 0.4 | 1.2 | GO:0052314 | phytoalexin metabolic process(GO:0052314) |
| 0.4 | 3.3 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.4 | 2.6 | GO:1903899 | positive regulation of PERK-mediated unfolded protein response(GO:1903899) |
| 0.4 | 1.5 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 0.4 | 0.7 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
| 0.4 | 1.4 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.3 | 1.0 | GO:0021934 | medulla oblongata development(GO:0021550) hindbrain tangential cell migration(GO:0021934) lateral line system development(GO:0048925) |
| 0.3 | 6.4 | GO:0008595 | tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) |
| 0.3 | 8.6 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.3 | 0.3 | GO:0002035 | brain renin-angiotensin system(GO:0002035) |
| 0.3 | 4.4 | GO:0021853 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.3 | 1.5 | GO:0003409 | optic cup structural organization(GO:0003409) |
| 0.3 | 1.5 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.3 | 2.1 | GO:0061146 | Peyer's patch morphogenesis(GO:0061146) |
| 0.3 | 2.2 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
| 0.3 | 1.4 | GO:0036371 | protein localization to T-tubule(GO:0036371) |
| 0.3 | 4.1 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) |
| 0.3 | 4.3 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.3 | 1.0 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 0.3 | 1.5 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.3 | 0.5 | GO:0042214 | terpene metabolic process(GO:0042214) |
| 0.2 | 3.9 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.2 | 2.6 | GO:0019720 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
| 0.2 | 2.6 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.2 | 1.4 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.2 | 0.7 | GO:0006579 | amino-acid betaine catabolic process(GO:0006579) |
| 0.2 | 0.9 | GO:0021986 | epithalamus development(GO:0021538) habenula development(GO:0021986) |
| 0.2 | 0.7 | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) |
| 0.2 | 0.7 | GO:0070175 | positive regulation of enamel mineralization(GO:0070175) |
| 0.2 | 1.1 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.2 | 0.7 | GO:1900158 | negative regulation of bone mineralization involved in bone maturation(GO:1900158) |
| 0.2 | 0.9 | GO:0045726 | positive regulation of integrin biosynthetic process(GO:0045726) |
| 0.2 | 0.9 | GO:0061743 | motor learning(GO:0061743) |
| 0.2 | 4.0 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.2 | 1.6 | GO:0070649 | polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649) |
| 0.2 | 1.0 | GO:0090214 | spongiotrophoblast layer developmental growth(GO:0090214) |
| 0.2 | 1.3 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.2 | 1.5 | GO:2000860 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 0.2 | 1.9 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.2 | 2.4 | GO:0010578 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
| 0.2 | 1.5 | GO:0071799 | response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799) |
| 0.2 | 1.3 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.2 | 1.4 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.2 | 0.7 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.2 | 0.9 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 0.2 | 0.8 | GO:0038156 | interleukin-3-mediated signaling pathway(GO:0038156) |
| 0.2 | 1.5 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.2 | 4.2 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.2 | 0.8 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.2 | 2.6 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.2 | 4.2 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.2 | 2.7 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.2 | 1.7 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.1 | 1.0 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
| 0.1 | 0.7 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.1 | 1.4 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.1 | 4.9 | GO:0001502 | cartilage condensation(GO:0001502) |
| 0.1 | 1.8 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.1 | 1.6 | GO:2000334 | blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 0.1 | 1.8 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.1 | 1.2 | GO:0003383 | apical constriction(GO:0003383) |
| 0.1 | 0.9 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 0.1 | 0.4 | GO:0006425 | glutaminyl-tRNA aminoacylation(GO:0006425) |
| 0.1 | 2.6 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 0.1 | 2.4 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.1 | 0.9 | GO:1900133 | regulation of renin secretion into blood stream(GO:1900133) |
| 0.1 | 13.0 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.1 | 1.6 | GO:0032596 | protein transport into membrane raft(GO:0032596) |
| 0.1 | 1.6 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.1 | 0.3 | GO:0043449 | cellular alkene metabolic process(GO:0043449) |
| 0.1 | 1.3 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.1 | 0.5 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.1 | 0.4 | GO:0048880 | sensory system development(GO:0048880) neural crest cell migration involved in sympathetic nervous system development(GO:1903045) |
| 0.1 | 0.5 | GO:0090341 | negative regulation of secretion of lysosomal enzymes(GO:0090341) |
| 0.1 | 0.6 | GO:0072658 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.1 | 0.7 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.1 | 0.5 | GO:0036414 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 0.1 | 0.7 | GO:0035989 | tendon development(GO:0035989) tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
| 0.1 | 1.5 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 0.1 | 1.1 | GO:0042177 | negative regulation of protein catabolic process(GO:0042177) |
| 0.1 | 2.8 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.1 | 1.4 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.1 | 2.8 | GO:0007625 | grooming behavior(GO:0007625) |
| 0.1 | 1.0 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.1 | 0.5 | GO:0010513 | positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) |
| 0.1 | 1.0 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.1 | 1.5 | GO:0015705 | iodide transport(GO:0015705) |
| 0.1 | 0.4 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
| 0.1 | 0.6 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.1 | 2.6 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.1 | 0.5 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.1 | 2.3 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.1 | 0.4 | GO:0001757 | somite specification(GO:0001757) sclerotome development(GO:0061056) |
| 0.1 | 1.5 | GO:0042908 | xenobiotic transport(GO:0042908) |
| 0.1 | 1.7 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
| 0.1 | 1.5 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.1 | 1.1 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.1 | 2.1 | GO:0043562 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.1 | 0.6 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.1 | 0.3 | GO:0006481 | C-terminal protein methylation(GO:0006481) |
| 0.1 | 0.6 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 0.1 | 0.8 | GO:0010944 | negative regulation of transcription by competitive promoter binding(GO:0010944) |
| 0.1 | 0.2 | GO:1990036 | calcium ion import into sarcoplasmic reticulum(GO:1990036) |
| 0.1 | 4.3 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.1 | 0.6 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 0.1 | 3.0 | GO:0007183 | SMAD protein complex assembly(GO:0007183) |
| 0.1 | 2.0 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.1 | 0.6 | GO:0070778 | L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712) |
| 0.1 | 1.3 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.1 | 0.3 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 0.1 | 0.4 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.1 | 1.2 | GO:0010886 | positive regulation of cholesterol storage(GO:0010886) |
| 0.1 | 0.6 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.1 | 0.3 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.1 | 0.3 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.1 | 0.4 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.1 | 2.1 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.1 | 1.3 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.1 | 1.0 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.1 | 0.3 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
| 0.1 | 0.6 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 0.1 | 2.1 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.1 | 0.4 | GO:0046098 | guanine metabolic process(GO:0046098) |
| 0.1 | 0.6 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.1 | 0.1 | GO:0030505 | inorganic diphosphate transport(GO:0030505) |
| 0.1 | 0.8 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 0.1 | 0.2 | GO:0001992 | regulation of systemic arterial blood pressure by vasopressin(GO:0001992) |
| 0.1 | 0.5 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.1 | 0.7 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.1 | 0.8 | GO:0030259 | lipid glycosylation(GO:0030259) |
| 0.1 | 0.5 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.1 | 0.7 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.1 | 0.9 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.1 | 0.9 | GO:0061162 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 0.1 | 0.4 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.1 | 1.0 | GO:0060088 | auditory receptor cell stereocilium organization(GO:0060088) |
| 0.1 | 1.3 | GO:0051775 | response to redox state(GO:0051775) |
| 0.1 | 1.9 | GO:0060065 | uterus development(GO:0060065) |
| 0.1 | 0.6 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.1 | 6.5 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 0.7 | GO:0072189 | ureter development(GO:0072189) |
| 0.1 | 0.9 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
| 0.1 | 1.1 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.1 | 0.2 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.1 | 0.3 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 0.1 | 0.3 | GO:1903753 | negative regulation of p38MAPK cascade(GO:1903753) |
| 0.1 | 0.3 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
| 0.0 | 0.4 | GO:0098912 | membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.0 | 0.3 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
| 0.0 | 1.7 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 2.0 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 0.2 | GO:0097476 | spinal cord motor neuron migration(GO:0097476) |
| 0.0 | 0.9 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.0 | 0.7 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.2 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.0 | 4.7 | GO:0050830 | defense response to Gram-positive bacterium(GO:0050830) |
| 0.0 | 1.3 | GO:0003351 | epithelial cilium movement(GO:0003351) |
| 0.0 | 4.7 | GO:0030239 | myofibril assembly(GO:0030239) |
| 0.0 | 1.8 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.0 | 1.5 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 2.2 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.0 | 0.6 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.0 | 0.3 | GO:0086016 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027) |
| 0.0 | 0.6 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.8 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.0 | 0.2 | GO:0060005 | vestibular reflex(GO:0060005) |
| 0.0 | 0.1 | GO:2000342 | negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342) |
| 0.0 | 16.8 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.0 | 6.2 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.4 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.0 | 0.5 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 0.2 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
| 0.0 | 0.1 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.0 | 0.6 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.0 | 0.9 | GO:0006833 | water transport(GO:0006833) |
| 0.0 | 2.0 | GO:0030195 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
| 0.0 | 0.8 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
| 0.0 | 0.5 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
| 0.0 | 1.4 | GO:1902808 | positive regulation of cell cycle G1/S phase transition(GO:1902808) |
| 0.0 | 0.9 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 1.8 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
| 0.0 | 0.4 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 0.3 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.0 | 0.0 | GO:0090107 | regulation of high-density lipoprotein particle assembly(GO:0090107) |
| 0.0 | 0.6 | GO:0010801 | negative regulation of peptidyl-threonine phosphorylation(GO:0010801) |
| 0.0 | 0.6 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.0 | 0.5 | GO:0010745 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) |
| 0.0 | 0.4 | GO:0043406 | positive regulation of MAP kinase activity(GO:0043406) |
| 0.0 | 0.6 | GO:0009408 | response to heat(GO:0009408) |
| 0.0 | 0.5 | GO:0001505 | regulation of neurotransmitter levels(GO:0001505) |
| 0.0 | 1.1 | GO:0030048 | actin filament-based movement(GO:0030048) |
| 0.0 | 0.1 | GO:0046500 | S-adenosylmethionine metabolic process(GO:0046500) |
| 0.0 | 0.2 | GO:0006665 | sphingolipid metabolic process(GO:0006665) |
| 0.0 | 0.2 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.0 | 0.1 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.0 | 0.5 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.0 | 1.2 | GO:0000060 | protein import into nucleus, translocation(GO:0000060) |
| 0.0 | 2.3 | GO:1900181 | negative regulation of protein localization to nucleus(GO:1900181) |
| 0.0 | 0.2 | GO:0048254 | snoRNA localization(GO:0048254) |
| 0.0 | 3.1 | GO:0051781 | positive regulation of cell division(GO:0051781) |
| 0.0 | 0.2 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.0 | 0.2 | GO:0072092 | ureteric bud elongation(GO:0060677) renal vesicle formation(GO:0072033) ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093) |
| 0.0 | 1.4 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 1.1 | GO:0007588 | excretion(GO:0007588) |
| 0.0 | 0.2 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 0.0 | 0.3 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
| 0.0 | 0.4 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.0 | 0.3 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
| 0.0 | 1.8 | GO:0007283 | spermatogenesis(GO:0007283) male gamete generation(GO:0048232) |
| 0.0 | 0.1 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 0.0 | 0.2 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 0.5 | GO:0001525 | angiogenesis(GO:0001525) |
| 0.0 | 0.9 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.0 | 0.6 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 0.4 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.0 | 1.2 | GO:0090090 | negative regulation of canonical Wnt signaling pathway(GO:0090090) |
| 0.0 | 0.3 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.0 | 0.2 | GO:0046785 | microtubule polymerization(GO:0046785) |
| 0.0 | 0.5 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.8 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.0 | 0.1 | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) |
| 0.0 | 1.0 | GO:0030593 | neutrophil chemotaxis(GO:0030593) |
| 0.0 | 0.1 | GO:0038098 | sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 0.0 | 0.1 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.0 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995) |
| 0.0 | 1.6 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 0.2 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.0 | 0.1 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 21.8 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 1.2 | 17.9 | GO:0030478 | actin cap(GO:0030478) |
| 0.9 | 2.7 | GO:0005595 | collagen type XII trimer(GO:0005595) |
| 0.9 | 2.6 | GO:0019008 | molybdopterin synthase complex(GO:0019008) |
| 0.7 | 7.8 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
| 0.7 | 2.7 | GO:0060187 | cell pole(GO:0060187) |
| 0.6 | 1.9 | GO:0044299 | C-fiber(GO:0044299) |
| 0.6 | 1.9 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.6 | 2.3 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.4 | 1.8 | GO:0030849 | autosome(GO:0030849) |
| 0.4 | 1.9 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.3 | 2.0 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.3 | 1.0 | GO:0033150 | cytoskeletal calyx(GO:0033150) |
| 0.3 | 2.5 | GO:1990357 | terminal web(GO:1990357) |
| 0.3 | 1.4 | GO:1990425 | ryanodine receptor complex(GO:1990425) |
| 0.3 | 3.2 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.2 | 8.6 | GO:0090533 | cation-transporting ATPase complex(GO:0090533) |
| 0.2 | 3.3 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.2 | 2.2 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.2 | 4.5 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.2 | 4.3 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 1.2 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.1 | 1.7 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.1 | 8.9 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 3.9 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 3.9 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 0.3 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.1 | 0.3 | GO:0097679 | other organism cytoplasm(GO:0097679) |
| 0.1 | 2.2 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 0.5 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 0.1 | 9.5 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 2.2 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 0.7 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.1 | 0.8 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.1 | 1.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 4.0 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 0.2 | GO:0044609 | DBIRD complex(GO:0044609) |
| 0.1 | 1.2 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.1 | 0.9 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.1 | 0.3 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.1 | 0.8 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.1 | 2.0 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 0.9 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.1 | 0.7 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 1.9 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 1.5 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.1 | 3.0 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 1.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 2.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 1.2 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.0 | 6.8 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.4 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.0 | 6.5 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 0.6 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.0 | 15.1 | GO:0030017 | sarcomere(GO:0030017) |
| 0.0 | 16.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.2 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.0 | 1.0 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.0 | 1.1 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 0.5 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.0 | 0.1 | GO:0036457 | keratohyalin granule(GO:0036457) |
| 0.0 | 0.2 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.0 | 0.2 | GO:1990393 | 3M complex(GO:1990393) |
| 0.0 | 1.2 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 0.3 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.0 | 5.1 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 1.8 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.9 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.0 | 1.7 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 3.4 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.4 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 0.3 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.0 | 0.6 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 0.3 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.0 | 1.6 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 3.8 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 1.4 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.2 | GO:0000333 | telomerase catalytic core complex(GO:0000333) |
| 0.0 | 0.2 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.0 | 3.5 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.0 | 0.3 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 10.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.1 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.0 | 2.0 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 1.2 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.8 | GO:0033202 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.0 | 0.7 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 0.6 | GO:0030658 | transport vesicle membrane(GO:0030658) |
| 0.0 | 3.7 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 3.4 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.5 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.4 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 3.1 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 1.0 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.0 | 0.5 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 1.3 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.3 | GO:0005883 | neurofilament(GO:0005883) |
| 0.0 | 1.6 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 0.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 0.3 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 0.2 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.0 | 0.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.9 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 1.8 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 1.6 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.3 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.0 | 0.3 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.0 | 1.3 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 1.8 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 0.6 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.0 | 0.2 | GO:0043235 | receptor complex(GO:0043235) |
| 0.0 | 5.2 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 0.3 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 1.0 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.0 | 1.8 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 1.9 | GO:0005875 | microtubule associated complex(GO:0005875) |
| 0.0 | 6.1 | GO:0009986 | cell surface(GO:0009986) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 22.8 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 1.2 | 8.6 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.9 | 2.7 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.8 | 2.5 | GO:0005427 | proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322) |
| 0.8 | 3.1 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 0.7 | 3.5 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.6 | 20.5 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.5 | 1.5 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
| 0.5 | 1.5 | GO:0004958 | prostaglandin F receptor activity(GO:0004958) |
| 0.5 | 2.8 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.5 | 2.3 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.4 | 4.4 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.4 | 1.3 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.4 | 1.2 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 0.4 | 3.1 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.4 | 1.9 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.4 | 5.7 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.3 | 1.7 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.3 | 5.7 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.3 | 1.0 | GO:0070698 | transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698) |
| 0.3 | 1.3 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.3 | 11.1 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.3 | 1.8 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.3 | 0.8 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.3 | 1.0 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.2 | 2.7 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.2 | 1.4 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.2 | 23.0 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.2 | 0.7 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.2 | 1.9 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.2 | 1.3 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.2 | 1.5 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 0.2 | 0.6 | GO:0016503 | pheromone receptor activity(GO:0016503) |
| 0.2 | 0.6 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.2 | 5.7 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.2 | 3.9 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.2 | 1.5 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.2 | 7.5 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.2 | 0.7 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 0.2 | 0.7 | GO:0046997 | oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
| 0.2 | 2.7 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.2 | 0.8 | GO:0004912 | interleukin-3 receptor activity(GO:0004912) |
| 0.2 | 4.6 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.2 | 0.8 | GO:0003947 | (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947) |
| 0.2 | 0.6 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.2 | 1.7 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.2 | 18.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.2 | 2.4 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
| 0.1 | 1.6 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.1 | 0.9 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.1 | 1.0 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.1 | 2.0 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.1 | 0.7 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.1 | 2.2 | GO:0043855 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.1 | 1.2 | GO:0043426 | MRF binding(GO:0043426) |
| 0.1 | 1.6 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.1 | 0.4 | GO:0070506 | high-density lipoprotein particle receptor activity(GO:0070506) |
| 0.1 | 1.1 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.1 | 0.4 | GO:0004819 | glutamine-tRNA ligase activity(GO:0004819) |
| 0.1 | 3.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 1.9 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.1 | 1.5 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
| 0.1 | 0.3 | GO:0005146 | leukemia inhibitory factor receptor binding(GO:0005146) |
| 0.1 | 2.5 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 0.5 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 0.1 | 0.4 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.1 | 0.9 | GO:0016679 | oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) |
| 0.1 | 2.2 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.1 | 7.5 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 1.5 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.1 | 6.1 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.1 | 2.2 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166) |
| 0.1 | 0.3 | GO:0004608 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 0.1 | 0.3 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
| 0.1 | 2.0 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.1 | 1.2 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.1 | 0.4 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.1 | 0.3 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 0.1 | 0.2 | GO:0086039 | lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039) |
| 0.1 | 0.3 | GO:0001595 | angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945) |
| 0.1 | 7.9 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 0.6 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.1 | 0.3 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.1 | 0.4 | GO:0032558 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
| 0.1 | 1.1 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.1 | 0.6 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.1 | 0.5 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.1 | 2.0 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 2.3 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 1.4 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.1 | 0.3 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.1 | 1.8 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.1 | 0.2 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.1 | 0.5 | GO:0032810 | sterol response element binding(GO:0032810) |
| 0.1 | 2.2 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 0.2 | GO:0051800 | phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800) |
| 0.1 | 0.6 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.1 | 4.8 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 0.2 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 0.9 | GO:0015250 | water channel activity(GO:0015250) |
| 0.1 | 0.9 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 0.3 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.1 | 1.2 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
| 0.1 | 1.1 | GO:0030674 | protein binding, bridging(GO:0030674) binding, bridging(GO:0060090) |
| 0.1 | 0.7 | GO:0099602 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.1 | 0.6 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.1 | 2.5 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 0.9 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.1 | 3.9 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.1 | 2.1 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.1 | 0.5 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 0.0 | 0.7 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 10.8 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 1.3 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.0 | 0.9 | GO:0008061 | chitin binding(GO:0008061) |
| 0.0 | 0.8 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.0 | 0.4 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.0 | 0.4 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.0 | 0.2 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.0 | 2.9 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.9 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 0.2 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.0 | 0.5 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.0 | 0.7 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.0 | 0.9 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.0 | 0.3 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.0 | 1.3 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 2.3 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 0.6 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 0.9 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 14.4 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 0.7 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 0.8 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.0 | 1.2 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 2.0 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.3 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.0 | 0.1 | GO:0008260 | 3-oxoacid CoA-transferase activity(GO:0008260) |
| 0.0 | 0.7 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 1.7 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.7 | GO:0043495 | protein anchor(GO:0043495) |
| 0.0 | 0.7 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 1.4 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 3.2 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.6 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 1.0 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 1.8 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 3.7 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.3 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.0 | 0.2 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.0 | 0.4 | GO:0016918 | retinal binding(GO:0016918) |
| 0.0 | 0.1 | GO:0019808 | polyamine binding(GO:0019808) |
| 0.0 | 0.6 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 0.3 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.3 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.0 | 0.8 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 1.2 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 12.9 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 2.3 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 0.4 | GO:0042923 | neuropeptide binding(GO:0042923) |
| 0.0 | 0.1 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.0 | 0.1 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 0.0 | 0.2 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.0 | 2.5 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.2 | GO:0005000 | vasopressin receptor activity(GO:0005000) |
| 0.0 | 0.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 2.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.8 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.3 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 0.5 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.1 | GO:0015252 | hydrogen ion channel activity(GO:0015252) |
| 0.0 | 3.2 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.4 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.1 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 0.9 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.4 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.0 | 0.1 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.0 | 0.2 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
| 0.0 | 1.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.2 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.0 | 0.2 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.0 | 0.5 | GO:0005539 | glycosaminoglycan binding(GO:0005539) |
| 0.0 | 0.1 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.0 | 0.4 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.6 | GO:0070063 | RNA polymerase binding(GO:0070063) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 29.4 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.2 | 11.3 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.2 | 6.1 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.2 | 11.6 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 0.7 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.1 | 0.8 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.1 | 2.4 | ST ADRENERGIC | Adrenergic Pathway |
| 0.1 | 5.7 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.1 | 2.3 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 2.2 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.1 | 24.3 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 5.5 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 3.0 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 5.6 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.1 | 6.6 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 2.3 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 2.0 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 3.8 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 3.3 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.3 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 1.8 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 1.1 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 2.0 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 10.5 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.7 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.0 | 0.9 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.6 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.9 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 2.0 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 12.6 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 3.8 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.7 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 1.2 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.2 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.0 | 0.6 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.0 | 0.8 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.5 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 1.3 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.0 | 0.8 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 0.8 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 0.9 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 0.9 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.4 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.0 | 1.1 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.3 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.6 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.0 | 0.4 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 1.0 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.1 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 0.3 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 18.8 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.4 | 22.7 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.3 | 22.2 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.2 | 6.6 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.1 | 6.0 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 2.0 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.1 | 11.6 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 2.2 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.1 | 6.8 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.1 | 1.5 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.1 | 4.2 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.1 | 3.4 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.1 | 3.2 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 1.9 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 1.7 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 3.1 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.1 | 2.0 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.1 | 1.3 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 2.0 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 1.1 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 1.6 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 1.9 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.1 | 0.9 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 1.5 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.1 | 1.2 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 2.3 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.8 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 1.7 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 2.3 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.9 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 1.4 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.7 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 2.5 | REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.0 | 0.5 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.4 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.0 | 0.4 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.0 | 1.0 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 0.6 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 5.2 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 0.5 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 1.0 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 1.8 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.8 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 3.2 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.8 | REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
| 0.0 | 0.5 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 1.2 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 0.2 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 1.8 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.7 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.5 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 0.3 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.3 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.0 | 0.3 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.0 | 0.5 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.1 | REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
| 0.0 | 0.6 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 0.2 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |