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Illumina Body Map 2, young vs old

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Results for HOXC12_HOXD12

Z-value: 0.22

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Transcription factors associated with HOXC12_HOXD12

Gene Symbol Gene ID Gene Info
HOXC12
ENSG00000123407.3 homeobox C12
HOXD12
ENSG00000170178.5 homeobox D12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC12hg19_v2_chr12_+_54348618_543486930.271.3e-01Click!
HOXD12hg19_v2_chr2_+_176964458_176964540-0.086.6e-01Click!

Activity profile of HOXC12_HOXD12 motif

Sorted Z-values of HOXC12_HOXD12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrY_+_2709527 7.05 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr12_+_54384370 3.09 ENST00000504315.1
HOXC6
homeobox C6
chrY_+_2709906 2.80 ENST00000430575.1
RPS4Y1
ribosomal protein S4, Y-linked 1
chr19_+_7011509 2.31 ENST00000377296.3
AC025278.1
Uncharacterized protein
chr20_+_36946029 2.26 ENST00000417318.1
BPI
bactericidal/permeability-increasing protein
chr2_-_152589670 2.10 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr14_+_39944025 1.96 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr7_-_27219849 1.71 ENST00000396344.4
HOXA10
homeobox A10
chrX_-_142605301 1.58 ENST00000370503.2
SPANXN3
SPANX family, member N3
chr20_+_36932521 1.36 ENST00000262865.4
BPI
bactericidal/permeability-increasing protein
chr8_-_33370607 1.35 ENST00000360742.5
ENST00000523305.1
TTI2
TELO2 interacting protein 2
chr1_+_156308245 1.29 ENST00000368253.2
ENST00000470342.1
ENST00000368254.1
TSACC
TSSK6 activating co-chaperone
chr2_+_132160448 1.25 ENST00000437751.1
AC073869.19
long intergenic non-protein coding RNA 1120
chr4_-_141419484 1.22 ENST00000515402.1
ENST00000515354.1
RP11-542P2.1
Glycosyltransferase 54 domain-containing protein
chr16_-_54304608 1.20 ENST00000561336.1
RP11-324D17.1
HCG2045435; Uncharacterized protein
chr12_-_13248562 1.18 ENST00000457134.2
ENST00000537302.1
GSG1
germ cell associated 1
chr6_-_49681235 1.15 ENST00000339139.4
CRISP2
cysteine-rich secretory protein 2
chr17_-_28257080 1.14 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2
slingshot protein phosphatase 2
chr1_-_26394114 1.12 ENST00000374272.3
TRIM63
tripartite motif containing 63, E3 ubiquitin protein ligase
chrX_-_77582980 1.12 ENST00000373304.3
CYSLTR1
cysteinyl leukotriene receptor 1
chr12_+_54402790 1.10 ENST00000040584.4
HOXC8
homeobox C8
chr3_-_51909600 1.08 ENST00000446461.1
IQCF5
IQ motif containing F5
chr2_+_190541153 1.07 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr4_-_164395014 1.05 ENST00000280605.3
TKTL2
transketolase-like 2
chr1_-_220220000 1.04 ENST00000366923.3
EPRS
glutamyl-prolyl-tRNA synthetase
chr7_+_76101379 1.03 ENST00000429179.1
DTX2
deltex homolog 2 (Drosophila)
chr9_-_7961080 1.02 ENST00000435444.1
RP11-29B9.2
RP11-29B9.2
chr12_+_54410664 1.02 ENST00000303406.4
HOXC4
homeobox C4
chr13_+_53030107 1.01 ENST00000490903.1
ENST00000480747.1
CKAP2
cytoskeleton associated protein 2
chr11_-_5531159 1.00 ENST00000445998.1
UBQLN3
ubiquilin 3
chr6_+_106988986 0.99 ENST00000457437.1
ENST00000535438.1
AIM1
absent in melanoma 1
chr20_-_18810797 0.97 ENST00000278779.4
C20orf78
chromosome 20 open reading frame 78
chr1_+_156308403 0.97 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC
TSSK6 activating co-chaperone
chr2_+_149974684 0.97 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chr2_+_176995011 0.95 ENST00000548663.1
ENST00000450510.2
HOXD8
homeobox D8
chr12_-_13248732 0.94 ENST00000396302.3
GSG1
germ cell associated 1
chr13_+_113030625 0.94 ENST00000283550.3
SPACA7
sperm acrosome associated 7
chr1_-_220219775 0.91 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr13_+_53029564 0.90 ENST00000468284.1
ENST00000378034.3
ENST00000258607.5
ENST00000378037.5
CKAP2
cytoskeleton associated protein 2
chr12_-_13248705 0.87 ENST00000396310.2
GSG1
germ cell associated 1
chr12_+_70219052 0.87 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chrX_-_133792480 0.86 ENST00000359237.4
PLAC1
placenta-specific 1
chr3_+_32737027 0.86 ENST00000454516.2
CNOT10
CCR4-NOT transcription complex, subunit 10
chr22_-_20307532 0.86 ENST00000405465.3
ENST00000248879.3
DGCR6L
DiGeorge syndrome critical region gene 6-like
chr5_-_176433565 0.86 ENST00000428382.2
UIMC1
ubiquitin interaction motif containing 1
chr10_+_124670121 0.86 ENST00000368894.1
FAM24A
family with sequence similarity 24, member A
chr7_-_27219632 0.85 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chr6_-_31681839 0.85 ENST00000409239.1
ENST00000461287.1
LY6G6E
XXbac-BPG32J3.20
lymphocyte antigen 6 complex, locus G6E (pseudogene)
Uncharacterized protein
chr14_+_22180536 0.84 ENST00000390424.2
TRAV2
T cell receptor alpha variable 2
chr10_-_1071796 0.82 ENST00000277517.1
IDI2
isopentenyl-diphosphate delta isomerase 2
chr12_+_123259063 0.81 ENST00000392441.4
ENST00000539171.1
CCDC62
coiled-coil domain containing 62
chr7_-_27179814 0.81 ENST00000522788.1
ENST00000521779.1
HOXA3
homeobox A3
chrY_+_26997726 0.80 ENST00000382296.2
DAZ4
deleted in azoospermia 4
chr1_-_91182794 0.80 ENST00000370445.4
BARHL2
BarH-like homeobox 2
chr7_-_27169801 0.80 ENST00000511914.1
HOXA4
homeobox A4
chr4_-_141419376 0.77 ENST00000511113.1
ENST00000503109.2
RP11-542P2.1
Glycosyltransferase 54 domain-containing protein
chr4_+_146601356 0.75 ENST00000438731.1
ENST00000511965.1
C4orf51
chromosome 4 open reading frame 51
chr7_-_144107320 0.74 ENST00000483238.1
ENST00000467773.1
NOBOX
NOBOX oogenesis homeobox
chr22_+_29168652 0.74 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr4_-_46911248 0.72 ENST00000355591.3
ENST00000505102.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr8_-_52721975 0.72 ENST00000356297.4
ENST00000543296.1
PXDNL
peroxidasin homolog (Drosophila)-like
chr3_-_108672742 0.71 ENST00000261047.3
GUCA1C
guanylate cyclase activator 1C
chr14_+_22947861 0.70 ENST00000390482.1
TRAJ57
T cell receptor alpha joining 57
chr14_-_64846033 0.70 ENST00000556556.1
CTD-2555O16.1
CTD-2555O16.1
chr17_-_42767092 0.68 ENST00000588687.1
CCDC43
coiled-coil domain containing 43
chr9_+_134065506 0.67 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr7_+_6797288 0.67 ENST00000433859.2
ENST00000359718.3
RSPH10B2
radial spoke head 10 homolog B2 (Chlamydomonas)
chr5_-_176433693 0.67 ENST00000507513.1
ENST00000511320.1
UIMC1
ubiquitin interaction motif containing 1
chr1_+_178694300 0.67 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chrX_-_55291163 0.66 ENST00000519203.1
ENST00000374951.1
PAGE3
P antigen family, member 3 (prostate associated)
chr7_+_138145145 0.65 ENST00000415680.2
TRIM24
tripartite motif containing 24
chr14_-_60952739 0.64 ENST00000555476.1
ENST00000321731.3
C14orf39
chromosome 14 open reading frame 39
chr5_+_35852797 0.64 ENST00000508941.1
IL7R
interleukin 7 receptor
chr8_+_33613265 0.64 ENST00000517292.1
RP11-317N12.1
RP11-317N12.1
chr17_-_46667594 0.63 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
HOXB3
homeobox B3
chr19_-_40790729 0.63 ENST00000423127.1
ENST00000583859.1
ENST00000456441.1
ENST00000452077.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr6_-_51952418 0.61 ENST00000371117.3
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr18_+_9885961 0.61 ENST00000306084.6
TXNDC2
thioredoxin domain containing 2 (spermatozoa)
chr5_-_180670370 0.61 ENST00000502844.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr8_-_38008783 0.61 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr7_+_138915102 0.60 ENST00000486663.1
UBN2
ubinuclein 2
chr14_+_22386325 0.60 ENST00000390439.2
TRAV13-2
T cell receptor alpha variable 13-2
chr2_-_211179883 0.59 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr18_+_9885760 0.59 ENST00000536353.2
ENST00000584255.1
TXNDC2
thioredoxin domain containing 2 (spermatozoa)
chr10_-_81270678 0.58 ENST00000538322.1
AL133481.1
Uncharacterized protein
chr8_-_144699668 0.58 ENST00000425753.2
TSTA3
tissue specific transplantation antigen P35B
chr8_-_144699628 0.57 ENST00000529048.1
ENST00000529064.1
TSTA3
tissue specific transplantation antigen P35B
chrX_-_15619076 0.57 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr18_+_9885934 0.56 ENST00000357775.5
TXNDC2
thioredoxin domain containing 2 (spermatozoa)
chr11_-_32457075 0.56 ENST00000448076.3
WT1
Wilms tumor 1
chr7_-_121944491 0.56 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr2_-_136875712 0.56 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr12_-_53074182 0.56 ENST00000252244.3
KRT1
keratin 1
chr1_+_158900568 0.56 ENST00000458222.1
PYHIN1
pyrin and HIN domain family, member 1
chr2_-_88285309 0.55 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr11_-_16419067 0.55 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr14_+_101123580 0.54 ENST00000556697.1
ENST00000360899.2
ENST00000553623.1
LINC00523
long intergenic non-protein coding RNA 523
chr2_-_225362533 0.54 ENST00000451538.1
CUL3
cullin 3
chr6_-_36515177 0.54 ENST00000229812.7
STK38
serine/threonine kinase 38
chr2_+_101869262 0.54 ENST00000289382.3
CNOT11
CCR4-NOT transcription complex, subunit 11
chr5_+_169010638 0.53 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr17_+_45286706 0.53 ENST00000393450.1
ENST00000572303.1
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr17_+_6679528 0.52 ENST00000321535.4
FBXO39
F-box protein 39
chr17_+_19091325 0.52 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr6_-_51952367 0.51 ENST00000340994.4
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chrX_+_23018058 0.51 ENST00000327968.5
DDX53
DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
chr17_-_46667628 0.51 ENST00000498678.1
HOXB3
homeobox B3
chr16_+_31085714 0.50 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646
zinc finger protein 646
chr5_-_39270725 0.50 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr3_-_18466026 0.49 ENST00000417717.2
SATB1
SATB homeobox 1
chr3_-_138739768 0.49 ENST00000329447.5
PRR23B
proline rich 23B
chr15_+_101459420 0.49 ENST00000388948.3
ENST00000284395.5
ENST00000534045.1
ENST00000532029.2
LRRK1
leucine-rich repeat kinase 1
chr16_-_20364122 0.49 ENST00000396138.4
ENST00000577168.1
UMOD
uromodulin
chr14_+_22968672 0.48 ENST00000390497.1
TRAJ40
T cell receptor alpha joining 40
chr17_+_29664830 0.47 ENST00000444181.2
ENST00000417592.2
NF1
neurofibromin 1
chr1_+_117297007 0.47 ENST00000369478.3
ENST00000369477.1
CD2
CD2 molecule
chr5_-_176433582 0.46 ENST00000506128.1
UIMC1
ubiquitin interaction motif containing 1
chr12_-_95945246 0.45 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr22_+_38035459 0.45 ENST00000357436.4
SH3BP1
SH3-domain binding protein 1
chr14_+_90422239 0.45 ENST00000393452.3
ENST00000554180.1
ENST00000393454.2
ENST00000553617.1
ENST00000335725.4
ENST00000357382.3
ENST00000556867.1
ENST00000553527.1
TDP1
tyrosyl-DNA phosphodiesterase 1
chr16_-_66907139 0.45 ENST00000561579.2
NAE1
NEDD8 activating enzyme E1 subunit 1
chr18_-_46895066 0.45 ENST00000583225.1
ENST00000584983.1
ENST00000583280.1
ENST00000581738.1
DYM
dymeclin
chr7_-_142169013 0.44 ENST00000454561.2
TRBV5-4
T cell receptor beta variable 5-4
chr7_+_76090993 0.44 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
DTX2
deltex homolog 2 (Drosophila)
chr1_+_151735431 0.44 ENST00000321531.5
ENST00000315067.8
OAZ3
ornithine decarboxylase antizyme 3
chr12_+_110940005 0.44 ENST00000409246.1
ENST00000392672.4
ENST00000409300.1
ENST00000409425.1
RAD9B
RAD9 homolog B (S. pombe)
chr15_+_66797627 0.43 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr13_+_113030658 0.43 ENST00000414180.1
ENST00000443541.1
SPACA7
sperm acrosome associated 7
chr2_+_135596106 0.43 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr7_-_6006768 0.43 ENST00000441023.2
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr18_+_61223393 0.42 ENST00000269491.1
ENST00000382768.1
SERPINB12
serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr15_-_34331243 0.42 ENST00000306730.3
AVEN
apoptosis, caspase activation inhibitor
chrX_-_100548045 0.42 ENST00000372907.3
ENST00000372905.2
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr1_+_47603109 0.42 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
CYP4A22
cytochrome P450, family 4, subfamily A, polypeptide 22
chr15_+_66797455 0.42 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr2_-_136873735 0.42 ENST00000409817.1
CXCR4
chemokine (C-X-C motif) receptor 4
chr7_-_142124565 0.41 ENST00000390376.2
TRBV6-8
T cell receptor beta variable 6-8
chr18_+_12703002 0.41 ENST00000590217.1
PSMG2
proteasome (prosome, macropain) assembly chaperone 2
chr7_+_63709496 0.40 ENST00000255746.4
ZNF679
zinc finger protein 679
chr13_-_24895566 0.40 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr19_+_13885252 0.40 ENST00000221576.4
C19orf53
chromosome 19 open reading frame 53
chr22_-_36925124 0.40 ENST00000457241.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr8_+_1993173 0.40 ENST00000523438.1
MYOM2
myomesin 2
chr1_-_247697141 0.40 ENST00000366487.3
OR2C3
olfactory receptor, family 2, subfamily C, member 3
chr8_+_1993152 0.39 ENST00000262113.4
MYOM2
myomesin 2
chr1_+_202431859 0.38 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr14_+_31028348 0.38 ENST00000550944.1
ENST00000438909.2
ENST00000553504.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr12_+_14956506 0.37 ENST00000330828.2
C12orf60
chromosome 12 open reading frame 60
chr7_-_27183263 0.37 ENST00000222726.3
HOXA5
homeobox A5
chr12_-_10875831 0.37 ENST00000279550.7
ENST00000228251.4
YBX3
Y box binding protein 3
chr16_+_67143828 0.37 ENST00000563853.2
ENST00000569914.1
ENST00000569600.1
C16orf70
chromosome 16 open reading frame 70
chr18_-_69449517 0.37 ENST00000584810.1
RP11-723G8.2
Uncharacterized protein
chr4_+_122722466 0.37 ENST00000243498.5
ENST00000379663.3
ENST00000509800.1
EXOSC9
exosome component 9
chrX_+_107037451 0.36 ENST00000372379.2
NCBP2L
nuclear cap binding protein subunit 2-like
chr12_-_59175485 0.36 ENST00000550678.1
ENST00000552201.1
RP11-767I20.1
RP11-767I20.1
chr1_+_100818009 0.36 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr5_+_169011033 0.36 ENST00000513795.1
SPDL1
spindle apparatus coiled-coil protein 1
chr8_-_66701319 0.36 ENST00000379419.4
PDE7A
phosphodiesterase 7A
chr17_-_60883993 0.36 ENST00000583803.1
ENST00000456609.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr4_-_46911223 0.35 ENST00000396533.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr15_+_72410629 0.35 ENST00000340912.4
ENST00000544171.1
SENP8
SUMO/sentrin specific peptidase family member 8
chr22_-_36925186 0.35 ENST00000541106.1
ENST00000455547.1
ENST00000432675.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr12_+_110940111 0.35 ENST00000409778.3
RAD9B
RAD9 homolog B (S. pombe)
chr11_-_19223523 0.35 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr17_-_34890617 0.35 ENST00000586886.1
ENST00000585719.1
ENST00000585818.1
MYO19
myosin XIX
chr5_+_39520499 0.34 ENST00000604954.1
CTD-2078B5.2
CTD-2078B5.2
chr17_-_42976736 0.34 ENST00000591382.1
ENST00000593072.1
ENST00000592576.1
ENST00000402521.3
EFTUD2
elongation factor Tu GTP binding domain containing 2
chr1_+_100817262 0.34 ENST00000455467.1
CDC14A
cell division cycle 14A
chr1_+_166958497 0.34 ENST00000367870.2
MAEL
maelstrom spermatogenic transposon silencer
chr6_+_4087664 0.34 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chr19_+_21106028 0.34 ENST00000597314.1
ENST00000601924.1
ZNF85
zinc finger protein 85
chr15_+_26360970 0.34 ENST00000556159.1
ENST00000557523.1
LINC00929
long intergenic non-protein coding RNA 929
chr7_+_138145076 0.33 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr11_+_110001723 0.33 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr1_-_7913089 0.33 ENST00000361696.5
UTS2
urotensin 2
chr4_-_83765613 0.33 ENST00000503937.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr3_-_108672609 0.33 ENST00000393963.3
ENST00000471108.1
GUCA1C
guanylate cyclase activator 1C
chr20_-_1569278 0.33 ENST00000262929.5
ENST00000567028.1
SIRPB1
RP4-576H24.4
signal-regulatory protein beta 1
Uncharacterized protein
chr16_+_67906919 0.33 ENST00000358933.5
EDC4
enhancer of mRNA decapping 4
chr16_+_67143880 0.32 ENST00000219139.3
ENST00000566026.1
C16orf70
chromosome 16 open reading frame 70
chr13_+_50570019 0.32 ENST00000442421.1
TRIM13
tripartite motif containing 13
chr8_-_101718991 0.32 ENST00000517990.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr1_-_173176452 0.32 ENST00000281834.3
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr16_-_88878305 0.32 ENST00000569616.1
ENST00000563655.1
ENST00000567713.1
ENST00000426324.2
ENST00000378364.3
APRT
adenine phosphoribosyltransferase
chr1_-_169680745 0.32 ENST00000236147.4
SELL
selectin L
chr21_+_17214724 0.32 ENST00000449491.1
USP25
ubiquitin specific peptidase 25
chr21_-_45960078 0.32 ENST00000400375.1
KRTAP10-1
keratin associated protein 10-1
chr2_+_170335924 0.32 ENST00000554017.1
ENST00000392663.2
ENST00000513963.1
BBS5
RP11-724O16.1
Bardet-Biedl syndrome 5
Bardet-Biedl syndrome 5 protein; Uncharacterized protein
chr14_+_22987424 0.32 ENST00000390511.1
TRAJ26
T cell receptor alpha joining 26
chr3_+_26735991 0.32 ENST00000456208.2
LRRC3B
leucine rich repeat containing 3B
chr7_-_105221898 0.31 ENST00000486180.1
ENST00000485614.1
ENST00000480514.1
EFCAB10
EF-hand calcium binding domain 10
chr12_-_10007448 0.31 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr3_-_179322436 0.31 ENST00000392659.2
ENST00000476781.1
MRPL47
mitochondrial ribosomal protein L47
chr7_+_80275953 0.31 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr8_-_87755878 0.31 ENST00000320005.5
CNGB3
cyclic nucleotide gated channel beta 3
chr4_-_153601136 0.31 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr19_-_55453077 0.31 ENST00000328092.5
ENST00000590030.1
NLRP7
NLR family, pyrin domain containing 7
chr7_-_142143973 0.31 ENST00000390373.2
TRBV6-7
T cell receptor beta variable 6-7 (non-functional)
chr15_+_26360932 0.31 ENST00000556213.1
LINC00929
long intergenic non-protein coding RNA 929
chr19_-_49496557 0.31 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
GYS1
glycogen synthase 1 (muscle)

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC12_HOXD12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.4 2.1 GO:0007525 somatic muscle development(GO:0007525)
0.3 1.2 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.3 1.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.2 2.0 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.2 1.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.2 2.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 0.8 GO:0050992 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.2 0.9 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.2 0.5 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.2 3.4 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.2 0.6 GO:0018963 insecticide metabolic process(GO:0017143) phthalate metabolic process(GO:0018963)
0.1 0.6 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.4 GO:0060435 bronchiole development(GO:0060435)
0.1 1.0 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.6 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.8 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.3 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 1.0 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.5 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.3 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.5 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.3 GO:0044209 AMP salvage(GO:0044209)
0.1 1.8 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.1 0.5 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.5 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.6 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.7 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 1.0 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.4 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.5 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.1 1.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.8 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.7 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.2 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.9 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.1 GO:0021550 medulla oblongata development(GO:0021550)
0.1 10.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.5 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.1 0.3 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.2 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.8 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 1.0 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.8 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.2 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 1.7 GO:0060065 uterus development(GO:0060065)
0.0 0.3 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.8 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 1.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 1.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.3 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.1 GO:0061156 pulmonary artery morphogenesis(GO:0061156) regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.5 GO:0000012 single strand break repair(GO:0000012)
0.0 0.2 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.2 GO:1904796 regulation of core promoter binding(GO:1904796)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0042220 response to cocaine(GO:0042220)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.4 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.2 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.4 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.5 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 1.1 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 1.1 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 1.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.8 GO:0001709 cell fate determination(GO:0001709)
0.0 4.5 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.5 GO:0036035 osteoclast development(GO:0036035)
0.0 1.1 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.7 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.2 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0097452 GAIT complex(GO:0097452)
0.2 0.9 GO:1990423 RZZ complex(GO:1990423)
0.2 0.8 GO:0030849 autosome(GO:0030849)
0.2 1.0 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 2.0 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.7 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 9.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.8 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.0 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.3 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.7 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.4 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 0.5 GO:0005827 polar microtubule(GO:0005827)
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 1.1 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.8 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 1.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.7 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.5 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.6 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 4.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.4 GO:0000243 commitment complex(GO:0000243)
0.0 1.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.4 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 1.1 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.0 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.4 1.2 GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.3 1.1 GO:0004802 transketolase activity(GO:0004802)
0.3 1.0 GO:0098808 mRNA cap binding(GO:0098808)
0.2 0.8 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.2 1.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.2 0.6 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 0.5 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 1.0 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.4 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.8 GO:0032089 NACHT domain binding(GO:0032089)
0.1 1.8 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 9.9 GO:0019843 rRNA binding(GO:0019843)
0.1 0.6 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.5 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.5 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 1.6 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.5 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 1.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.9 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.0 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.4 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.3 GO:0002060 purine nucleobase binding(GO:0002060)
0.1 0.3 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 3.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 1.4 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.2 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.1 0.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.4 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.5 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.1 1.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.3 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.1 1.8 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 2.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0005119 smoothened binding(GO:0005119)
0.0 1.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.5 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.9 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 3.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0031711 angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 1.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 2.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0019864 IgG binding(GO:0019864)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0070026 nitric oxide binding(GO:0070026)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 1.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 2.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.1 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.9 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 1.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.2 PID ATM PATHWAY ATM pathway
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.8 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.7 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 10.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 2.0 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 3.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.7 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint