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Illumina Body Map 2, young vs old

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Results for HOXC13

Z-value: 0.15

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Transcription factors associated with HOXC13

Gene Symbol Gene ID Gene Info
ENSG00000123364.3 homeobox C13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC13hg19_v2_chr12_+_54332535_543326360.301.0e-01Click!

Activity profile of HOXC13 motif

Sorted Z-values of HOXC13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_71532668 7.31 ENST00000510437.1
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_-_71532601 5.35 ENST00000510614.1
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr14_-_106668095 3.76 ENST00000390606.2
immunoglobulin heavy variable 3-20
chr14_-_106725723 3.08 ENST00000390609.2
immunoglobulin heavy variable 3-23
chr18_+_61554932 2.65 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr4_-_71532339 2.44 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr22_+_23101182 2.41 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr22_+_23114284 2.29 ENST00000390313.2
immunoglobulin lambda variable 3-12
chr2_+_89986318 2.27 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr7_+_80275953 2.26 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36 molecule (thrombospondin receptor)
chr15_+_57891609 2.12 ENST00000569089.1
myocardial zonula adherens protein
chr7_+_80275752 2.10 ENST00000419819.2
CD36 molecule (thrombospondin receptor)
chr7_+_80275621 2.07 ENST00000426978.1
ENST00000432207.1
CD36 molecule (thrombospondin receptor)
chr7_+_80275663 2.06 ENST00000413265.1
CD36 molecule (thrombospondin receptor)
chr10_+_51549498 1.94 ENST00000358559.2
ENST00000298239.6
microseminoprotein, beta-
chr11_+_118175132 1.94 ENST00000361763.4
CD3e molecule, epsilon (CD3-TCR complex)
chr9_-_37034028 1.92 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
paired box 5
chr14_-_106963409 1.92 ENST00000390621.2
immunoglobulin heavy variable 1-45
chr1_-_169680745 1.76 ENST00000236147.4
selectin L
chr5_+_35852797 1.68 ENST00000508941.1
interleukin 7 receptor
chr1_+_109656719 1.67 ENST00000457623.2
ENST00000529753.1
KIAA1324
chr1_+_192544857 1.67 ENST00000367459.3
ENST00000469578.2
regulator of G-protein signaling 1
chr14_-_106816253 1.63 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr7_+_142031986 1.61 ENST00000547918.2
T cell receptor beta variable 7-1 (non-functional)
chr12_+_47473369 1.61 ENST00000546455.1
PC-esterase domain containing 1B
chr12_-_114841703 1.59 ENST00000526441.1
T-box 5
chr1_+_109656579 1.58 ENST00000526264.1
ENST00000369939.3
KIAA1324
chr3_+_130300585 1.57 ENST00000511332.1
collagen, type VI, alpha 6
chr6_-_33041378 1.56 ENST00000428995.1
major histocompatibility complex, class II, DP alpha 1
chr6_-_32784687 1.52 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr21_+_43823983 1.47 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
ubiquitin associated and SH3 domain containing A
chr17_-_74639730 1.43 ENST00000589992.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr16_+_12059050 1.39 ENST00000396495.3
tumor necrosis factor receptor superfamily, member 17
chr18_-_70532906 1.39 ENST00000299430.2
ENST00000397929.1
neuropilin (NRP) and tolloid (TLL)-like 1
chr20_+_36946029 1.38 ENST00000417318.1
bactericidal/permeability-increasing protein
chr1_+_158815588 1.37 ENST00000438394.1
myeloid cell nuclear differentiation antigen
chr17_-_74639886 1.37 ENST00000156626.7
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr6_+_127898312 1.33 ENST00000329722.7
chromosome 6 open reading frame 58
chr3_-_172241250 1.30 ENST00000420541.2
ENST00000241261.2
tumor necrosis factor (ligand) superfamily, member 10
chr14_+_97925151 1.29 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1
chr6_-_49681235 1.25 ENST00000339139.4
cysteine-rich secretory protein 2
chr8_-_95274536 1.21 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr8_-_86290333 1.20 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
carbonic anhydrase I
chr3_-_112320749 1.16 ENST00000610103.1
RP11-572C15.6
chr15_+_94774767 1.14 ENST00000543482.1
multiple C2 domains, transmembrane 2
chr19_+_859654 1.13 ENST00000592860.1
complement factor D (adipsin)
chr15_+_77287715 1.09 ENST00000559161.1
proline-serine-threonine phosphatase interacting protein 1
chr15_+_71228826 1.09 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
leucine rich repeat containing 49
chr14_+_22409308 1.08 ENST00000390441.2
T cell receptor alpha variable 9-2
chr12_-_54689532 1.06 ENST00000540264.2
ENST00000312156.4
nuclear factor, erythroid 2
chr19_-_18632861 1.05 ENST00000262809.4
elongation factor RNA polymerase II
chr6_+_126221034 0.98 ENST00000433571.1
nuclear receptor coactivator 7
chr16_-_68033356 0.98 ENST00000393847.1
ENST00000573808.1
ENST00000572624.1
dipeptidase 2
chr6_+_151358048 0.98 ENST00000450635.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr2_+_103035102 0.97 ENST00000264260.2
interleukin 18 receptor accessory protein
chr9_+_67977438 0.94 ENST00000456982.1
Protein LOC644249
chr11_+_107643129 0.93 ENST00000447610.1
Uncharacterized protein
chr10_+_30723533 0.92 ENST00000413724.1
mitogen-activated protein kinase kinase kinase 8
chr16_+_33605231 0.92 ENST00000570121.2
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr1_+_174844645 0.89 ENST00000486220.1
RAB GTPase activating protein 1-like
chr1_+_109656532 0.88 ENST00000531664.1
ENST00000534476.1
KIAA1324
chr4_-_147866960 0.87 ENST00000513335.1
tetratricopeptide repeat domain 29
chr19_+_41698927 0.86 ENST00000310054.4
cytochrome P450, family 2, subfamily S, polypeptide 1
chr12_-_47473425 0.85 ENST00000550413.1
adhesion molecule with Ig-like domain 2
chr10_+_70847852 0.85 ENST00000242465.3
serglycin
chr12_+_96883347 0.84 ENST00000524981.4
ENST00000298953.3
chromosome 12 open reading frame 55
chr6_-_112080256 0.84 ENST00000462856.2
ENST00000229471.4
FYN oncogene related to SRC, FGR, YES
chr13_-_46964177 0.83 ENST00000389908.3
KIAA0226-like
chr8_-_27850180 0.81 ENST00000380385.2
ENST00000301906.4
ENST00000354914.3
scavenger receptor class A, member 5 (putative)
chr3_-_160116995 0.80 ENST00000465537.1
ENST00000486856.1
ENST00000468218.1
ENST00000478370.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr19_+_36545833 0.80 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WD repeat domain 62
chr12_-_9885888 0.79 ENST00000327839.3
C-type lectin-like 1
chr15_+_71184931 0.79 ENST00000560369.1
ENST00000260382.5
leucine rich repeat containing 49
chr7_+_106505696 0.78 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr9_+_112887772 0.77 ENST00000259318.7
A kinase (PRKA) anchor protein 2
chr7_-_86595190 0.76 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324-like
chr19_+_7011509 0.74 ENST00000377296.3
Uncharacterized protein
chr3_-_160117035 0.74 ENST00000489004.1
ENST00000496589.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr3_+_167582561 0.73 ENST00000463642.1
ENST00000464514.1
RP11-298O21.6
RP11-298O21.7
chr9_-_130533615 0.73 ENST00000373277.4
SH2 domain containing 3C
chr4_+_124571409 0.71 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
long intergenic non-protein coding RNA 1091
chr15_+_74421961 0.71 ENST00000565159.1
ENST00000567206.1
immunoglobulin superfamily containing leucine-rich repeat 2
chr11_+_62037622 0.71 ENST00000227918.2
ENST00000525380.1
secretoglobin, family 2A, member 2
chr20_-_44420507 0.70 ENST00000243938.4
WAP four-disulfide core domain 3
chr10_-_21186144 0.70 ENST00000377119.1
nebulette
chr12_-_91546926 0.70 ENST00000550758.1
decorin
chr15_+_71185148 0.70 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr7_+_106505912 0.69 ENST00000359195.3
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr7_-_29152509 0.69 ENST00000448959.1
carboxypeptidase, vitellogenic-like
chr4_-_120243545 0.68 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr8_-_27850141 0.68 ENST00000524352.1
scavenger receptor class A, member 5 (putative)
chr7_-_4877677 0.67 ENST00000538469.1
Ras association and DIL domains
chr3_-_49837254 0.66 ENST00000412678.2
ENST00000343366.4
ENST00000487256.1
cadherin-related family member 4
chr5_-_39270725 0.65 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr12_-_9885702 0.65 ENST00000542530.1
C-type lectin-like 1
chr1_+_174128639 0.65 ENST00000251507.4
RAB GTPase activating protein 1-like
chr12_-_53207842 0.64 ENST00000458244.2
keratin 4
chr1_+_158979680 0.63 ENST00000368131.4
ENST00000340979.6
interferon, gamma-inducible protein 16
chr12_+_75874580 0.62 ENST00000456650.3
GLI pathogenesis-related 1
chr12_-_123728548 0.62 ENST00000545406.1
M-phase phosphoprotein 9
chr1_-_155880672 0.62 ENST00000609492.1
ENST00000368322.3
Ras-like without CAAX 1
chr5_-_180076613 0.62 ENST00000261937.6
ENST00000393347.3
fms-related tyrosine kinase 4
chr1_+_158979686 0.62 ENST00000368132.3
ENST00000295809.7
interferon, gamma-inducible protein 16
chr14_-_92333873 0.61 ENST00000435962.2
tandem C2 domains, nuclear
chr17_+_35732955 0.60 ENST00000300618.4
chromosome 17 open reading frame 78
chr6_-_138060103 0.60 ENST00000411615.1
ENST00000419220.1
RP11-356I2.1
chr11_+_101785727 0.59 ENST00000263468.8
KIAA1377
chr9_-_139137648 0.58 ENST00000358701.5
quiescin Q6 sulfhydryl oxidase 2
chr2_+_33683109 0.57 ENST00000437184.1
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr7_-_92777606 0.57 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr22_+_38142235 0.57 ENST00000407319.2
ENST00000403663.2
ENST00000428075.1
TRIO and F-actin binding protein
chr12_-_91539918 0.56 ENST00000548218.1
decorin
chr6_-_112081113 0.56 ENST00000517419.1
FYN oncogene related to SRC, FGR, YES
chr6_-_128222103 0.56 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
thymocyte selection associated
chr17_-_39140549 0.55 ENST00000377755.4
keratin 40
chr1_+_206579736 0.55 ENST00000439126.1
SLIT-ROBO Rho GTPase activating protein 2
chr7_+_6797288 0.55 ENST00000433859.2
ENST00000359718.3
radial spoke head 10 homolog B2 (Chlamydomonas)
chr3_-_108672742 0.54 ENST00000261047.3
guanylate cyclase activator 1C
chr3_+_160117062 0.54 ENST00000497311.1
structural maintenance of chromosomes 4
chr8_+_77318769 0.53 ENST00000518732.1
long intergenic non-protein coding RNA 1111
chr1_+_174128704 0.53 ENST00000457696.1
RAB GTPase activating protein 1-like
chr12_-_92539614 0.52 ENST00000256015.3
B-cell translocation gene 1, anti-proliferative
chr1_+_171107241 0.52 ENST00000236166.3
flavin containing monooxygenase 6 pseudogene
chr19_+_21106081 0.52 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
zinc finger protein 85
chr4_+_8321882 0.52 ENST00000509453.1
ENST00000503186.1
RP11-774O3.2
RP11-774O3.1
chr5_-_180076580 0.51 ENST00000502649.1
fms-related tyrosine kinase 4
chr3_-_108672609 0.51 ENST00000393963.3
ENST00000471108.1
guanylate cyclase activator 1C
chr10_-_6019984 0.49 ENST00000525219.2
interleukin 15 receptor, alpha
chr7_-_38389573 0.49 ENST00000390344.2
T cell receptor gamma variable 5
chr19_-_48753064 0.49 ENST00000520153.1
ENST00000357778.5
ENST00000520015.1
caspase recruitment domain family, member 8
chr11_-_102576537 0.49 ENST00000260229.4
matrix metallopeptidase 27
chr3_+_50211240 0.49 ENST00000420831.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_+_43766668 0.48 ENST00000441333.2
ENST00000538015.1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr12_-_57630873 0.48 ENST00000556732.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr16_-_9770700 0.48 ENST00000561538.1
Uncharacterized protein
chrY_+_14958970 0.47 ENST00000453031.1
ubiquitin specific peptidase 9, Y-linked
chr15_+_26640219 0.46 ENST00000451579.1
AC009878.2
chr18_-_24722995 0.46 ENST00000581714.1
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr5_-_169725231 0.46 ENST00000046794.5
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_+_56910048 0.45 ENST00000509844.1
CTD-2023N9.3
chr14_-_88200641 0.45 ENST00000556168.1
RP11-1152H15.1
chr22_+_32439019 0.44 ENST00000266088.4
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr9_-_95244781 0.44 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
asporin
chr4_+_147145709 0.44 ENST00000504313.1
Uncharacterized protein
chr1_+_43766642 0.44 ENST00000372476.3
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr6_+_33239787 0.43 ENST00000439602.2
ENST00000474973.1
ribosomal protein S18
chr21_+_25801088 0.43 ENST00000415182.1
AP000476.1
chr17_+_35732916 0.43 ENST00000586700.1
chromosome 17 open reading frame 78
chr12_-_89413456 0.42 ENST00000500381.2
RP11-13A1.1
chr6_+_21666633 0.42 ENST00000606851.1
cancer susceptibility candidate 15 (non-protein coding)
chr11_+_61891445 0.42 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
inner centromere protein antigens 135/155kDa
chr5_+_140180635 0.42 ENST00000522353.2
ENST00000532566.2
protocadherin alpha 3
chr20_+_37590942 0.42 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr2_+_48796120 0.41 ENST00000394754.1
STON1-GTF2A1L readthrough
chr12_+_93115281 0.41 ENST00000549856.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr1_+_166958346 0.41 ENST00000367872.4
maelstrom spermatogenic transposon silencer
chr3_+_111630451 0.41 ENST00000495180.1
pleckstrin homology-like domain, family B, member 2
chr1_-_109656439 0.40 ENST00000369949.4
chromosome 1 open reading frame 194
chr4_+_88720698 0.40 ENST00000226284.5
integrin-binding sialoprotein
chr7_-_41742697 0.40 ENST00000242208.4
inhibin, beta A
chr11_-_114430570 0.39 ENST00000251921.2
neurexophilin and PC-esterase domain family, member 1
chr2_+_33359646 0.39 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr11_+_3011093 0.38 ENST00000332881.2
HCG1782999; PRO0943; Uncharacterized protein
chr3_+_57875738 0.38 ENST00000417128.1
ENST00000438794.1
sarcolemma associated protein
chr2_+_162016804 0.38 ENST00000392749.2
ENST00000440506.1
TRAF family member-associated NFKB activator
chr2_+_33359687 0.38 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chr6_-_36515177 0.38 ENST00000229812.7
serine/threonine kinase 38
chr19_-_54618650 0.38 ENST00000391757.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr19_-_48759119 0.37 ENST00000522889.1
ENST00000520753.1
ENST00000519940.1
ENST00000519332.1
ENST00000521437.1
ENST00000520007.1
ENST00000521613.1
caspase recruitment domain family, member 8
chr18_-_73967160 0.37 ENST00000579714.1
RP11-94B19.7
chr6_-_130031358 0.37 ENST00000368149.2
Rho GTPase activating protein 18
chr1_-_168464875 0.37 ENST00000422253.1
RP5-968D22.3
chr7_-_16872932 0.36 ENST00000419572.2
ENST00000412973.1
anterior gradient 2
chr18_-_5544241 0.36 ENST00000341928.2
ENST00000540638.2
erythrocyte membrane protein band 4.1-like 3
chr17_-_8286484 0.36 ENST00000582556.1
ENST00000584164.1
ENST00000293842.5
ENST00000584343.1
ENST00000578812.1
ENST00000583011.1
ribosomal protein L26
chr11_+_4510109 0.36 ENST00000307632.3
olfactory receptor, family 52, subfamily K, member 1
chr4_-_164395014 0.36 ENST00000280605.3
transketolase-like 2
chr3_-_123339343 0.35 ENST00000578202.1
myosin light chain kinase
chr3_+_101498269 0.34 ENST00000491511.2
neurexophilin and PC-esterase domain family, member 3
chr2_+_162016916 0.34 ENST00000405852.1
TRAF family member-associated NFKB activator
chr9_-_5304432 0.34 ENST00000416837.1
ENST00000308420.3
relaxin 2
chr18_-_52989525 0.33 ENST00000457482.3
transcription factor 4
chr3_-_99569821 0.32 ENST00000487087.1
filamin A interacting protein 1-like
chrX_+_13707235 0.32 ENST00000464506.1
RAB9A, member RAS oncogene family
chr17_+_68047418 0.32 ENST00000586373.1
ENST00000588782.1
long intergenic non-protein coding RNA 1028
chr16_+_86612112 0.32 ENST00000320241.3
forkhead box L1
chr2_-_225811747 0.31 ENST00000409592.3
dedicator of cytokinesis 10
chr7_-_25219897 0.31 ENST00000283905.3
ENST00000409280.1
ENST00000415598.1
chromosome 7 open reading frame 31
chr11_-_58378759 0.30 ENST00000601906.1
Uncharacterized protein
chr11_+_63606373 0.30 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MAP/microtubule affinity-regulating kinase 2
chr15_+_77713299 0.30 ENST00000559099.1
high mobility group 20A
chrX_-_38186775 0.30 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
retinitis pigmentosa GTPase regulator
chr22_+_39916558 0.30 ENST00000337304.2
ENST00000396680.1
activating transcription factor 4
chr7_+_63709496 0.29 ENST00000255746.4
zinc finger protein 679
chr19_+_21264980 0.29 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
zinc finger protein 714
chr5_-_176433565 0.29 ENST00000428382.2
ubiquitin interaction motif containing 1
chr2_+_162016827 0.29 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TRAF family member-associated NFKB activator
chr19_+_36545781 0.29 ENST00000388999.3
WD repeat domain 62
chr9_+_40028620 0.28 ENST00000426179.1
AL353791.1
chr12_+_93096759 0.28 ENST00000544406.2
chromosome 12 open reading frame 74

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.5 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.5 1.6 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.5 1.5 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.4 1.9 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.3 1.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 0.8 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.3 1.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3 1.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 1.5 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.2 1.7 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 4.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 1.0 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.5 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 9.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.4 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 2.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.9 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 1.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 1.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.6 GO:0030047 actin modification(GO:0030047)
0.1 0.4 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 1.0 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 1.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.8 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 0.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 1.4 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 1.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.2 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.9 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 1.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.4 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.4 GO:1902231 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 1.1 GO:0001946 lymphangiogenesis(GO:0001946) regulation of blood vessel remodeling(GO:0060312) positive regulation of protein kinase C signaling(GO:0090037)
0.1 1.4 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.4 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 1.3 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.3 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 1.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.4 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 1.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 1.5 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.5 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.0 0.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.3 GO:0052405 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.6 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.2 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 1.1 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 3.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.6 GO:0033198 response to ATP(GO:0033198)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 0.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 2.9 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 5.2 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 1.2 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.3 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.0 1.8 GO:0042073 intraciliary transport(GO:0042073)
0.0 1.1 GO:0007099 centriole replication(GO:0007099)
0.0 2.5 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 2.1 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 2.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.4 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 8.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 9.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 3.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.4 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.4 GO:0030849 autosome(GO:0030849)
0.1 1.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.5 GO:0036398 TCR signalosome(GO:0036398)
0.1 1.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.4 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.9 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.3 GO:1990037 Lewy body core(GO:1990037)
0.0 1.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.5 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.4 GO:0000801 central element(GO:0000801)
0.0 1.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.5 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 1.0 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 1.1 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 5.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.1 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 3.9 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 2.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.0 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 3.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 8.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.4 1.7 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.4 1.1 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.3 2.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 1.8 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 3.3 GO:0042608 T cell receptor binding(GO:0042608)
0.2 1.0 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 3.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 1.0 GO:0050436 microfibril binding(GO:0050436)
0.2 1.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 1.2 GO:0004064 arylesterase activity(GO:0004064)
0.1 9.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.9 GO:0032089 NACHT domain binding(GO:0032089)
0.1 1.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.9 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.9 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.6 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.3 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.1 0.4 GO:0004802 transketolase activity(GO:0004802)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.5 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.4 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 1.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.2 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 8.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.6 GO:0045159 myosin II binding(GO:0045159)
0.0 1.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.8 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 2.5 GO:0005518 collagen binding(GO:0005518)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 1.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 3.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 8.5 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 1.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.9 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 1.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.0 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell