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Illumina Body Map 2, young vs old

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Results for HOXC9

Z-value: 0.10

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Transcription factors associated with HOXC9

Gene Symbol Gene ID Gene Info
HOXC9
ENSG00000180806.4 homeobox C9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC9hg19_v2_chr12_+_54393880_54393962-0.412.0e-02Click!

Activity profile of HOXC9 motif

Sorted Z-values of HOXC9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_72649763 4.86 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr4_-_70626314 4.58 ENST00000510821.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr4_+_155484155 4.42 ENST00000509493.1
FGB
fibrinogen beta chain
chr4_+_155484103 4.27 ENST00000302068.4
FGB
fibrinogen beta chain
chr9_-_104198042 3.72 ENST00000374855.4
ALDOB
aldolase B, fructose-bisphosphate
chr10_-_96829246 3.53 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr5_-_135290651 3.41 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chr5_-_135290705 3.27 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr10_+_5238793 3.02 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr19_-_58864848 2.70 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr1_+_47603109 2.67 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
CYP4A22
cytochrome P450, family 4, subfamily A, polypeptide 22
chr10_-_13344341 2.59 ENST00000396920.3
PHYH
phytanoyl-CoA 2-hydroxylase
chr12_+_20963647 2.54 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr5_+_36606700 2.41 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_90222610 2.37 ENST00000300055.5
PLIN1
perilipin 1
chr15_-_90222642 2.35 ENST00000430628.2
PLIN1
perilipin 1
chr17_-_9694614 2.35 ENST00000330255.5
ENST00000571134.1
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chr22_+_21133469 2.33 ENST00000406799.1
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr10_-_113943447 2.16 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr2_-_105030466 2.06 ENST00000449772.1
AC068535.3
AC068535.3
chr6_+_111408698 2.06 ENST00000368851.5
SLC16A10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr17_+_67498295 2.05 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr4_+_69681710 2.05 ENST00000265403.7
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B10
chrX_+_105936982 2.02 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr7_+_138915102 2.02 ENST00000486663.1
UBN2
ubinuclein 2
chrX_-_15332665 1.99 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chrX_+_105937068 1.99 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr4_-_100065419 1.92 ENST00000504125.1
ENST00000505590.1
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr4_-_100065440 1.86 ENST00000508393.1
ENST00000265512.7
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr3_+_149191723 1.84 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr7_+_137761167 1.82 ENST00000432161.1
AKR1D1
aldo-keto reductase family 1, member D1
chr10_-_27529486 1.78 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr5_-_35991535 1.75 ENST00000507113.1
ENST00000274278.3
UGT3A1
UDP glycosyltransferase 3 family, polypeptide A1
chr4_-_69536346 1.74 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr4_-_100065389 1.73 ENST00000512499.1
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr2_-_169887827 1.66 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr14_+_60712463 1.65 ENST00000325642.3
ENST00000529574.1
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr12_-_21757774 1.65 ENST00000261195.2
GYS2
glycogen synthase 2 (liver)
chr16_+_72090053 1.63 ENST00000576168.2
ENST00000567185.3
ENST00000567612.2
HP
haptoglobin
chr17_+_67498538 1.58 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr8_-_81083890 1.55 ENST00000518937.1
TPD52
tumor protein D52
chr8_-_17555164 1.54 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr14_+_74083548 1.52 ENST00000381139.1
ACOT6
acyl-CoA thioesterase 6
chr2_-_200715834 1.50 ENST00000420128.1
ENST00000416668.1
FTCDNL1
formiminotransferase cyclodeaminase N-terminal like
chr12_+_20963632 1.49 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chrM_+_10464 1.48 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr11_+_22694123 1.47 ENST00000534801.1
GAS2
growth arrest-specific 2
chr18_-_74839891 1.42 ENST00000581878.1
MBP
myelin basic protein
chr3_-_196242233 1.41 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr8_-_81083731 1.41 ENST00000379096.5
TPD52
tumor protein D52
chr16_-_48281305 1.41 ENST00000356608.2
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr17_-_9683238 1.38 ENST00000571771.1
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chrX_+_43515467 1.36 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr16_-_48281444 1.33 ENST00000537808.1
ENST00000569991.1
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr1_+_220863187 1.32 ENST00000294889.5
C1orf115
chromosome 1 open reading frame 115
chr7_-_44580861 1.31 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1L1
NPC1-like 1
chr7_-_113559104 1.30 ENST00000284601.3
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr12_+_104235229 1.30 ENST00000551650.1
RP11-650K20.3
Uncharacterized protein
chr19_-_36304201 1.30 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr2_-_230096756 1.29 ENST00000354069.6
PID1
phosphotyrosine interaction domain containing 1
chr17_+_7348658 1.28 ENST00000570557.1
ENST00000536404.2
ENST00000576360.1
CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr6_+_143447322 1.28 ENST00000458219.1
AIG1
androgen-induced 1
chr4_-_70626430 1.26 ENST00000310613.3
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr8_-_42396185 1.25 ENST00000518717.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr4_+_187148556 1.22 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr7_+_5468362 1.20 ENST00000608012.1
RP11-1275H24.3
RP11-1275H24.3
chr10_-_115614127 1.19 ENST00000369305.1
DCLRE1A
DNA cross-link repair 1A
chr1_+_202385953 1.16 ENST00000466968.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr2_+_27719697 1.14 ENST00000264717.2
ENST00000424318.2
GCKR
glucokinase (hexokinase 4) regulator
chr8_-_105479270 1.11 ENST00000521573.2
ENST00000351513.2
DPYS
dihydropyrimidinase
chr14_+_39944025 1.09 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr2_-_200715573 1.09 ENST00000420922.2
FTCDNL1
formiminotransferase cyclodeaminase N-terminal like
chr14_+_67291158 1.08 ENST00000555456.1
GPHN
gephyrin
chr9_-_95055923 1.07 ENST00000430417.1
IARS
isoleucyl-tRNA synthetase
chr14_+_21387491 1.06 ENST00000258817.2
RP11-84C10.2
RP11-84C10.2
chr11_+_19798964 1.06 ENST00000527559.2
NAV2
neuron navigator 2
chr8_-_17579726 1.06 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr16_+_71560154 1.04 ENST00000539698.3
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr8_+_145215928 1.02 ENST00000528919.1
MROH1
maestro heat-like repeat family member 1
chr16_-_12897642 1.02 ENST00000433677.2
ENST00000261660.4
ENST00000381774.4
CPPED1
calcineurin-like phosphoesterase domain containing 1
chr16_-_66584059 1.02 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2
thymidine kinase 2, mitochondrial
chr11_+_65266507 1.00 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr9_-_93405352 0.99 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr14_+_21359558 0.98 ENST00000304639.3
RNASE3
ribonuclease, RNase A family, 3
chr8_-_82608409 0.98 ENST00000518568.1
SLC10A5
solute carrier family 10, member 5
chr4_+_70894130 0.98 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr6_+_158733692 0.98 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr11_+_46366918 0.97 ENST00000528615.1
ENST00000395574.3
DGKZ
diacylglycerol kinase, zeta
chr8_+_9009202 0.97 ENST00000518496.1
RP11-10A14.4
Uncharacterized protein
chr7_-_111424462 0.97 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr2_+_234526272 0.96 ENST00000373450.4
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr8_-_80993010 0.95 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr17_-_28257080 0.94 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2
slingshot protein phosphatase 2
chr16_+_71560023 0.94 ENST00000572450.1
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr10_-_94257512 0.94 ENST00000371581.5
IDE
insulin-degrading enzyme
chr8_+_104033296 0.94 ENST00000521514.1
ENST00000518738.1
ATP6V1C1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr11_+_22688150 0.93 ENST00000454584.2
GAS2
growth arrest-specific 2
chr5_-_65018834 0.93 ENST00000506816.1
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr17_+_58018269 0.93 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr12_+_25348186 0.93 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYRM5
LYR motif containing 5
chr16_-_66907139 0.92 ENST00000561579.2
NAE1
NEDD8 activating enzyme E1 subunit 1
chr7_-_111424506 0.92 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chr8_+_104033277 0.91 ENST00000518857.1
ENST00000395862.3
ATP6V1C1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr1_+_212965170 0.91 ENST00000532324.1
ENST00000366974.4
ENST00000530441.1
ENST00000526641.1
ENST00000531963.1
ENST00000366973.4
ENST00000526997.1
ENST00000488246.2
TATDN3
TatD DNase domain containing 3
chr1_+_12524965 0.90 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr12_+_25348139 0.90 ENST00000557540.2
ENST00000381356.4
LYRM5
LYR motif containing 5
chr1_-_212004090 0.88 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr1_+_241695424 0.88 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr6_+_131571535 0.87 ENST00000474850.2
AKAP7
A kinase (PRKA) anchor protein 7
chr16_-_66583994 0.87 ENST00000564917.1
TK2
thymidine kinase 2, mitochondrial
chr12_+_58176525 0.87 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr20_-_45980621 0.86 ENST00000446894.1
ZMYND8
zinc finger, MYND-type containing 8
chr18_+_32558380 0.86 ENST00000588349.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr10_+_24755416 0.85 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr4_+_71600063 0.84 ENST00000513597.1
RUFY3
RUN and FYVE domain containing 3
chr13_-_52027134 0.84 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr11_-_13517565 0.83 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr1_+_40862501 0.82 ENST00000539317.1
SMAP2
small ArfGAP2
chr20_+_57414743 0.81 ENST00000313949.7
GNAS
GNAS complex locus
chr9_+_80912059 0.81 ENST00000347159.2
ENST00000376588.3
PSAT1
phosphoserine aminotransferase 1
chr5_-_148442584 0.80 ENST00000394358.2
ENST00000512049.1
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chrX_+_120181457 0.80 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr10_+_115614370 0.79 ENST00000369301.3
NHLRC2
NHL repeat containing 2
chr20_-_36152914 0.79 ENST00000397131.1
BLCAP
bladder cancer associated protein
chr9_-_21187598 0.77 ENST00000421715.1
IFNA4
interferon, alpha 4
chr12_-_118628315 0.77 ENST00000540561.1
TAOK3
TAO kinase 3
chr6_-_135424186 0.77 ENST00000529882.1
HBS1L
HBS1-like (S. cerevisiae)
chrX_+_150565038 0.77 ENST00000370361.1
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr3_+_16306691 0.76 ENST00000285083.5
ENST00000605932.1
ENST00000435829.2
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr20_+_5987890 0.75 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr1_-_19426149 0.74 ENST00000429347.2
UBR4
ubiquitin protein ligase E3 component n-recognin 4
chr7_+_80275663 0.74 ENST00000413265.1
CD36
CD36 molecule (thrombospondin receptor)
chr1_-_54355430 0.74 ENST00000371399.1
ENST00000072644.1
ENST00000412288.1
YIPF1
Yip1 domain family, member 1
chr20_+_57414795 0.73 ENST00000371098.2
ENST00000371075.3
GNAS
GNAS complex locus
chr9_-_130889990 0.72 ENST00000449878.1
PTGES2
prostaglandin E synthase 2
chr7_+_7196565 0.71 ENST00000429911.1
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr16_+_58074069 0.71 ENST00000570065.1
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr10_-_127505167 0.71 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chrM_+_10053 0.70 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr11_+_22688615 0.70 ENST00000533363.1
GAS2
growth arrest-specific 2
chrX_+_139791917 0.70 ENST00000607004.1
ENST00000370535.3
LINC00632
long intergenic non-protein coding RNA 632
chr12_-_63328817 0.70 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr8_+_132916318 0.69 ENST00000254624.5
ENST00000522709.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr2_-_122262593 0.69 ENST00000418989.1
CLASP1
cytoplasmic linker associated protein 1
chr12_-_118628350 0.69 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr2_-_172750733 0.67 ENST00000392592.4
ENST00000422440.2
SLC25A12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr2_+_48541776 0.66 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr10_-_24770632 0.66 ENST00000596413.1
AL353583.1
AL353583.1
chr17_-_42767092 0.66 ENST00000588687.1
CCDC43
coiled-coil domain containing 43
chr14_+_53173910 0.66 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr17_+_55162453 0.65 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
AKAP1
A kinase (PRKA) anchor protein 1
chr1_+_146714291 0.65 ENST00000431239.1
ENST00000369259.3
ENST00000369258.4
ENST00000361293.5
CHD1L
chromodomain helicase DNA binding protein 1-like
chr16_-_66583701 0.65 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
TK2
thymidine kinase 2, mitochondrial
chr6_-_52859968 0.64 ENST00000370959.1
GSTA4
glutathione S-transferase alpha 4
chr6_-_109702885 0.64 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr2_+_233390890 0.63 ENST00000258385.3
ENST00000536614.1
ENST00000457943.2
CHRND
cholinergic receptor, nicotinic, delta (muscle)
chr17_-_10372875 0.63 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr14_+_97925151 0.63 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1
CTD-2506J14.1
chr12_-_90049878 0.63 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr20_+_30697298 0.62 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr8_-_62602327 0.62 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr2_+_233390863 0.61 ENST00000449596.1
ENST00000543200.1
CHRND
cholinergic receptor, nicotinic, delta (muscle)
chr4_-_85654615 0.61 ENST00000514711.1
WDFY3
WD repeat and FYVE domain containing 3
chr4_-_69111401 0.61 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr9_+_103947311 0.60 ENST00000395056.2
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr21_-_27423339 0.60 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr8_-_93978333 0.59 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK
triple QxxK/R motif containing
chr12_-_90049828 0.59 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr2_+_62132781 0.59 ENST00000311832.5
COMMD1
copper metabolism (Murr1) domain containing 1
chr2_+_207630081 0.58 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FASTKD2
FAST kinase domains 2
chr14_+_21387508 0.58 ENST00000555624.1
RP11-84C10.2
RP11-84C10.2
chr14_+_53173890 0.58 ENST00000445930.2
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr9_-_95055956 0.58 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr6_-_146057144 0.58 ENST00000367519.3
EPM2A
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr5_-_139930713 0.57 ENST00000602657.1
SRA1
steroid receptor RNA activator 1
chr18_+_32558208 0.57 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr17_+_44803922 0.57 ENST00000465370.1
NSF
N-ethylmaleimide-sensitive factor
chr9_-_95056010 0.57 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr2_-_200320768 0.57 ENST00000428695.1
SATB2
SATB homeobox 2
chr2_+_187371440 0.57 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr8_-_93978216 0.56 ENST00000517751.1
ENST00000524107.1
TRIQK
triple QxxK/R motif containing
chr8_-_93978346 0.56 ENST00000523580.1
TRIQK
triple QxxK/R motif containing
chr7_+_80275621 0.56 ENST00000426978.1
ENST00000432207.1
CD36
CD36 molecule (thrombospondin receptor)
chr8_-_93978357 0.56 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK
triple QxxK/R motif containing
chr16_+_53412368 0.56 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr9_+_131549610 0.54 ENST00000223865.8
TBC1D13
TBC1 domain family, member 13
chr1_-_113478603 0.54 ENST00000443580.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr12_+_32687221 0.54 ENST00000525053.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr9_-_69262509 0.54 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
CBWD6
COBW domain containing 6
chr1_-_212965104 0.54 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1
NSL1, MIS12 kinetochore complex component
chr12_-_11091862 0.54 ENST00000537503.1
TAS2R14
taste receptor, type 2, member 14
chr2_+_62132800 0.53 ENST00000538736.1
COMMD1
copper metabolism (Murr1) domain containing 1
chr10_-_128110441 0.53 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chr6_-_83903600 0.52 ENST00000506587.1
ENST00000507554.1
PGM3
phosphoglucomutase 3
chr9_-_70490107 0.52 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5
COBW domain containing 5
chr4_-_176733377 0.52 ENST00000505375.1
GPM6A
glycoprotein M6A
chr1_-_205091115 0.51 ENST00000264515.6
ENST00000367164.1
RBBP5
retinoblastoma binding protein 5
chr18_-_12656715 0.51 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
SPIRE1
spire-type actin nucleation factor 1
chr3_+_69811858 0.51 ENST00000433517.1
MITF
microphthalmia-associated transcription factor
chr8_-_93978309 0.50 ENST00000517858.1
ENST00000378861.5
TRIQK
triple QxxK/R motif containing

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.8 3.9 GO:0072709 cellular response to sorbitol(GO:0072709)
0.7 9.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.6 3.7 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.6 2.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.5 1.6 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.5 2.6 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.5 2.5 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.4 1.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.4 3.0 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.4 1.8 GO:0030573 bile acid catabolic process(GO:0030573)
0.4 1.1 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.3 2.3 GO:0008218 bioluminescence(GO:0008218)
0.3 5.5 GO:0006069 ethanol oxidation(GO:0006069)
0.3 4.0 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.3 0.8 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3 1.7 GO:0015722 canalicular bile acid transport(GO:0015722)
0.3 1.1 GO:0019482 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860)
0.3 3.2 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.3 1.3 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.2 2.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.4 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2 1.9 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 0.7 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.2 0.9 GO:1901143 insulin catabolic process(GO:1901143)
0.2 0.9 GO:0016598 protein arginylation(GO:0016598)
0.2 6.8 GO:0009812 flavonoid metabolic process(GO:0009812)
0.2 1.7 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.2 1.8 GO:0030242 pexophagy(GO:0030242)
0.2 1.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 1.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 1.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 2.2 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 0.5 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.2 0.7 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 1.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 0.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 2.1 GO:0070327 aromatic amino acid transport(GO:0015801) thyroid hormone transport(GO:0070327)
0.2 0.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 2.0 GO:0006477 protein sulfation(GO:0006477)
0.2 4.9 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 1.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 1.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 1.4 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 1.2 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.8 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.1 0.4 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.5 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.6 GO:0071873 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.5 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 1.1 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.6 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.5 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.3 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.1 1.5 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 2.7 GO:0015865 purine nucleotide transport(GO:0015865)
0.1 0.4 GO:1904501 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 1.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 1.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 4.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.3 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.1 0.9 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.8 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.3 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.5 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 1.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 1.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.6 GO:0035973 aggrephagy(GO:0035973)
0.1 0.6 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.5 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.3 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 1.9 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.1 3.8 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 0.2 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.3 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 1.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.9 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.3 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.7 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 1.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.7 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 1.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 1.0 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.6 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.5 GO:0015747 urate transport(GO:0015747)
0.0 2.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.8 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.4 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.7 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.3 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.6 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.3 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.0 4.2 GO:0030183 B cell differentiation(GO:0030183)
0.0 2.9 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 0.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.4 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.2 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 2.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0072513 semicircular canal morphogenesis(GO:0048752) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.8 GO:0042246 tissue regeneration(GO:0042246)
0.0 1.0 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.9 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.1 GO:0043316 cytotoxic T cell degranulation(GO:0043316) positive regulation of constitutive secretory pathway(GO:1903435)
0.0 1.2 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.8 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 3.5 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0046426 regulation of JAK-STAT cascade(GO:0046425) negative regulation of JAK-STAT cascade(GO:0046426) regulation of STAT cascade(GO:1904892) negative regulation of STAT cascade(GO:1904893)
0.0 0.3 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.9 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.5 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.6 GO:0014823 response to activity(GO:0014823)
0.0 0.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 4.5 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.2 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.6 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.8 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.7 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 4.0 GO:0007050 cell cycle arrest(GO:0007050)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.7 GO:0005577 fibrinogen complex(GO:0005577)
0.4 1.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 1.9 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2 1.7 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2 0.7 GO:0031592 centrosomal corona(GO:0031592)
0.2 0.6 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 1.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.5 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 1.4 GO:0033269 internode region of axon(GO:0033269)
0.1 1.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 2.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 2.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 3.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.9 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.6 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.6 GO:0000125 PCAF complex(GO:0000125)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 4.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.4 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.8 GO:0032039 integrator complex(GO:0032039)
0.1 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 3.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0034464 BBSome(GO:0034464)
0.0 1.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 4.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.7 GO:0032433 filopodium tip(GO:0032433)
0.0 0.7 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.2 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.2 GO:0071437 invadopodium(GO:0071437)
0.0 3.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 1.1 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 1.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 5.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.6 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 1.3 GO:0031672 A band(GO:0031672)
0.0 2.8 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0005840 ribosome(GO:0005840)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 4.4 GO:0005770 late endosome(GO:0005770)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0019115 benzaldehyde dehydrogenase activity(GO:0019115)
1.6 4.9 GO:1902271 D3 vitamins binding(GO:1902271)
0.9 2.6 GO:0048244 phytanoyl-CoA dioxygenase activity(GO:0048244)
0.7 2.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.7 3.5 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.6 1.8 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.6 3.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.6 2.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.6 1.7 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.5 2.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.4 2.5 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.4 1.1 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.3 1.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.3 0.9 GO:0031626 beta-endorphin binding(GO:0031626)
0.3 3.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 0.9 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.3 1.6 GO:0030492 hemoglobin binding(GO:0030492)
0.3 0.8 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.2 2.0 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 2.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 1.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 0.9 GO:0004057 arginyltransferase activity(GO:0004057)
0.2 2.7 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 1.1 GO:0002054 nucleobase binding(GO:0002054) dihydropyrimidinase activity(GO:0004157)
0.2 5.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 0.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 2.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.8 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 0.5 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.2 5.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 0.7 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.2 1.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 2.7 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 1.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.7 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 3.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 1.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 6.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.4 GO:0033149 FFAT motif binding(GO:0033149)
0.1 1.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.5 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 2.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 3.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 1.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.9 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.4 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 1.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 1.9 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 1.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 9.0 GO:0051087 chaperone binding(GO:0051087)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 1.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.6 GO:0051425 PTB domain binding(GO:0051425)
0.0 1.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 1.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 1.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 1.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 2.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.7 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 1.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0005542 folic acid binding(GO:0005542)
0.0 0.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 3.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 4.6 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 8.2 PID CMYB PATHWAY C-MYB transcription factor network
0.1 4.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 4.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 4.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 3.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 2.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.7 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.4 5.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.3 4.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 5.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 3.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 4.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 4.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 4.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 3.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 4.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 3.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 3.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 2.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 4.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 2.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 4.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 4.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.6 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 2.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.9 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 2.9 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 2.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells