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Illumina Body Map 2, young vs old

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Results for HOXD4

Z-value: 0.47

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Transcription factors associated with HOXD4

Gene Symbol Gene ID Gene Info
HOXD4
ENSG00000170166.5 homeobox D4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD4hg19_v2_chr2_+_177015950_177015950-0.125.0e-01Click!

Activity profile of HOXD4 motif

Sorted Z-values of HOXD4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_48483736 2.64 ENST00000417307.2
ENST00000559641.1
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr4_+_155484155 2.60 ENST00000509493.1
FGB
fibrinogen beta chain
chr4_+_155484103 2.55 ENST00000302068.4
FGB
fibrinogen beta chain
chr5_+_101569696 2.08 ENST00000597120.1
AC008948.1
AC008948.1
chr15_+_84115868 1.83 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr6_-_87804815 1.64 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr10_-_50970322 1.46 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr2_+_155555201 1.45 ENST00000544049.1
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr3_-_170744498 1.45 ENST00000382808.4
ENST00000314251.3
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr20_-_45980621 1.26 ENST00000446894.1
ZMYND8
zinc finger, MYND-type containing 8
chr3_-_190167571 1.25 ENST00000354905.2
TMEM207
transmembrane protein 207
chr4_-_36245561 1.21 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_70505358 1.20 ENST00000457664.2
ENST00000604629.1
ENST00000604021.1
UGT2A2
UDP glucuronosyltransferase 2 family, polypeptide A2
chr8_+_50822344 1.17 ENST00000518864.1
SNTG1
syntrophin, gamma 1
chr3_+_142342228 1.17 ENST00000337777.3
PLS1
plastin 1
chr2_+_234590556 1.12 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr6_+_123317116 1.11 ENST00000275162.5
CLVS2
clavesin 2
chr7_+_123488124 1.09 ENST00000476325.1
HYAL4
hyaluronoglucosaminidase 4
chrX_+_37850026 0.98 ENST00000341016.3
CXorf27
chromosome X open reading frame 27
chr15_-_54025300 0.96 ENST00000559418.1
WDR72
WD repeat domain 72
chr4_+_74347400 0.92 ENST00000226355.3
AFM
afamin
chr17_-_50235423 0.92 ENST00000340813.6
CA10
carbonic anhydrase X
chr10_-_98119030 0.92 ENST00000371172.3
ENST00000393871.1
ENST00000419479.1
OPALIN
oligodendrocytic myelin paranodal and inner loop protein
chr2_+_191045656 0.89 ENST00000443551.2
C2orf88
chromosome 2 open reading frame 88
chr1_+_197237352 0.87 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
CRB1
crumbs homolog 1 (Drosophila)
chr12_-_39734783 0.87 ENST00000552961.1
KIF21A
kinesin family member 21A
chr20_-_43729750 0.86 ENST00000537075.1
ENST00000306117.1
KCNS1
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
chr17_-_64225508 0.83 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr10_-_61899124 0.81 ENST00000373815.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr8_+_79503458 0.79 ENST00000518467.1
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr1_-_190446759 0.79 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr2_-_166060552 0.78 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr7_+_29186174 0.75 ENST00000439384.1
CHN2
chimerin 2
chr5_-_150727111 0.72 ENST00000335244.4
ENST00000521967.1
SLC36A2
solute carrier family 36 (proton/amino acid symporter), member 2
chr1_-_238108575 0.71 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr2_-_31361543 0.71 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr18_-_74839891 0.68 ENST00000581878.1
MBP
myelin basic protein
chr5_-_13944652 0.68 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr4_+_146539415 0.68 ENST00000281317.5
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr2_+_166095898 0.68 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr2_-_159237472 0.67 ENST00000409187.1
CCDC148
coiled-coil domain containing 148
chr2_-_165424973 0.67 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr9_-_93405352 0.66 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr2_-_163695128 0.65 ENST00000332142.5
KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr2_+_171034646 0.65 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr5_-_78809950 0.64 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chrX_+_37865804 0.64 ENST00000297875.2
ENST00000357972.5
SYTL5
synaptotagmin-like 5
chr18_+_22040620 0.63 ENST00000426880.2
HRH4
histamine receptor H4
chr18_+_68002675 0.63 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chrX_+_149867681 0.63 ENST00000438018.1
ENST00000436701.1
MTMR1
myotubularin related protein 1
chr3_+_111718173 0.60 ENST00000494932.1
TAGLN3
transgelin 3
chr2_-_225434538 0.60 ENST00000409096.1
CUL3
cullin 3
chrX_+_56590002 0.59 ENST00000338222.5
UBQLN2
ubiquilin 2
chr8_-_40200877 0.58 ENST00000521030.1
CTA-392C11.1
CTA-392C11.1
chr18_-_61311485 0.57 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chrX_+_130192318 0.56 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr5_-_55412774 0.56 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr4_+_69313145 0.54 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr1_+_149754227 0.53 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr1_+_115572415 0.53 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta
chr15_-_94614049 0.53 ENST00000556447.1
ENST00000555772.1
CTD-3049M7.1
CTD-3049M7.1
chr7_+_29186192 0.52 ENST00000539406.1
CHN2
chimerin 2
chr2_-_166060571 0.51 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr3_+_142342240 0.50 ENST00000497199.1
PLS1
plastin 1
chr7_-_15014398 0.50 ENST00000437998.1
DGKB
diacylglycerol kinase, beta 90kDa
chr3_+_158787098 0.50 ENST00000397832.2
ENST00000451172.1
ENST00000482126.1
IQCJ
IQ motif containing J
chr8_+_42552503 0.50 ENST00000534391.1
CHRNB3
cholinergic receptor, nicotinic, beta 3 (neuronal)
chr13_-_61989655 0.49 ENST00000409204.4
PCDH20
protocadherin 20
chr4_-_46996424 0.49 ENST00000264318.3
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr1_-_151762900 0.48 ENST00000440583.2
TDRKH
tudor and KH domain containing
chr1_-_182921119 0.47 ENST00000423786.1
SHCBP1L
SHC SH2-domain binding protein 1-like
chr17_-_78450398 0.46 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr1_-_28384598 0.45 ENST00000373864.1
EYA3
eyes absent homolog 3 (Drosophila)
chr1_+_42846443 0.44 ENST00000410070.2
ENST00000431473.3
RIMKLA
ribosomal modification protein rimK-like family member A
chr15_+_54793169 0.44 ENST00000559093.1
UNC13C
unc-13 homolog C (C. elegans)
chr2_-_163695238 0.44 ENST00000328032.4
KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr12_-_81763184 0.43 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr5_-_110848253 0.43 ENST00000505803.1
ENST00000502322.1
STARD4
StAR-related lipid transfer (START) domain containing 4
chr10_-_17171785 0.43 ENST00000377823.1
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr20_-_29978286 0.42 ENST00000376315.2
DEFB119
defensin, beta 119
chr8_-_27941359 0.42 ENST00000418860.1
NUGGC
nuclear GTPase, germinal center associated
chr4_-_76944621 0.42 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr1_-_151762943 0.42 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH
tudor and KH domain containing
chr3_+_178276488 0.42 ENST00000432997.1
ENST00000455865.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr1_-_120935894 0.41 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr13_-_45768841 0.40 ENST00000379108.1
KCTD4
potassium channel tetramerization domain containing 4
chr14_+_29236269 0.39 ENST00000313071.4
FOXG1
forkhead box G1
chr8_-_42698292 0.39 ENST00000529779.1
THAP1
THAP domain containing, apoptosis associated protein 1
chr3_-_18480173 0.39 ENST00000414509.1
SATB1
SATB homeobox 1
chr2_+_234826016 0.38 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr6_-_136847099 0.38 ENST00000438100.2
MAP7
microtubule-associated protein 7
chr7_+_101460882 0.38 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1
cut-like homeobox 1
chr9_+_97562440 0.37 ENST00000395357.2
C9orf3
chromosome 9 open reading frame 3
chr16_-_3350614 0.37 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr4_+_146560245 0.36 ENST00000541599.1
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr16_+_84801852 0.36 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr7_-_38293030 0.36 ENST00000390333.1
TRGJ2
T cell receptor gamma joining 2
chr9_-_7961080 0.35 ENST00000435444.1
RP11-29B9.2
RP11-29B9.2
chr6_-_49931818 0.35 ENST00000322066.3
DEFB114
defensin, beta 114
chr11_-_36310958 0.35 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMMD9
COMM domain containing 9
chr11_-_57519253 0.35 ENST00000422652.1
ENST00000527995.1
BTBD18
BTB (POZ) domain containing 18
chr2_-_99279928 0.35 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr4_-_89442940 0.34 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr11_-_16419067 0.34 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr15_-_64386120 0.34 ENST00000300030.3
FAM96A
family with sequence similarity 96, member A
chr7_-_121944491 0.33 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr18_+_32402321 0.32 ENST00000587723.1
DTNA
dystrobrevin, alpha
chr10_+_69869237 0.32 ENST00000373675.3
MYPN
myopalladin
chr15_-_64385981 0.32 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
FAM96A
family with sequence similarity 96, member A
chr3_-_157221380 0.31 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr16_-_29910853 0.31 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr11_-_55371874 0.31 ENST00000302231.4
OR4C11
olfactory receptor, family 4, subfamily C, member 11
chr1_+_84630574 0.30 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_118628315 0.30 ENST00000540561.1
TAOK3
TAO kinase 3
chr1_-_231560790 0.30 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr3_-_18480260 0.30 ENST00000454909.2
SATB1
SATB homeobox 1
chr1_+_109265033 0.30 ENST00000445274.1
FNDC7
fibronectin type III domain containing 7
chr12_+_32654965 0.29 ENST00000472289.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr14_-_99947121 0.29 ENST00000329331.3
ENST00000436070.2
SETD3
SET domain containing 3
chr6_+_72926145 0.29 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr16_+_87636474 0.28 ENST00000284262.2
JPH3
junctophilin 3
chr1_+_214161854 0.28 ENST00000435016.1
PROX1
prospero homeobox 1
chr13_+_37581115 0.28 ENST00000481013.1
EXOSC8
exosome component 8
chr2_+_224822121 0.28 ENST00000258383.3
MRPL44
mitochondrial ribosomal protein L44
chr5_-_160279207 0.27 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr2_+_88047606 0.27 ENST00000359481.4
PLGLB2
plasminogen-like B2
chr3_-_178103080 0.27 ENST00000414475.1
RP11-33A14.1
RP11-33A14.1
chr7_-_137028498 0.27 ENST00000393083.2
PTN
pleiotrophin
chr1_+_182419261 0.27 ENST00000294854.8
ENST00000542961.1
RGSL1
regulator of G-protein signaling like 1
chr8_-_72274467 0.27 ENST00000340726.3
EYA1
eyes absent homolog 1 (Drosophila)
chr11_-_72492878 0.26 ENST00000535054.1
ENST00000545082.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr4_+_130014836 0.26 ENST00000502887.1
C4orf33
chromosome 4 open reading frame 33
chr12_+_28605426 0.26 ENST00000542801.1
CCDC91
coiled-coil domain containing 91
chr14_-_99947168 0.26 ENST00000331768.5
SETD3
SET domain containing 3
chr17_+_41132564 0.26 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chrX_-_92928557 0.25 ENST00000373079.3
ENST00000475430.2
NAP1L3
nucleosome assembly protein 1-like 3
chr12_+_9980113 0.25 ENST00000537723.1
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr9_+_273038 0.25 ENST00000487230.1
ENST00000469391.1
DOCK8
dedicator of cytokinesis 8
chr2_-_207024233 0.25 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr7_+_77428149 0.25 ENST00000415251.2
ENST00000275575.7
PHTF2
putative homeodomain transcription factor 2
chr12_+_16109519 0.25 ENST00000526530.1
DERA
deoxyribose-phosphate aldolase (putative)
chr15_-_56209306 0.25 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr2_-_235363231 0.24 ENST00000439798.1
AC097713.4
AC097713.4
chr7_+_55433131 0.24 ENST00000254770.2
LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr3_+_97483572 0.24 ENST00000335979.2
ENST00000394206.1
ARL6
ADP-ribosylation factor-like 6
chr7_-_122339162 0.24 ENST00000340112.2
RNF133
ring finger protein 133
chr3_+_140981456 0.24 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr12_+_96196875 0.24 ENST00000553095.1
RP11-536G4.1
Uncharacterized protein
chr2_+_204571375 0.23 ENST00000374478.4
CD28
CD28 molecule
chr7_+_77428066 0.23 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chr18_-_19283649 0.23 ENST00000584464.1
ENST00000578270.1
ABHD3
abhydrolase domain containing 3
chr1_+_84630645 0.23 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_+_158787041 0.23 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr14_-_21058982 0.23 ENST00000556526.1
RNASE12
ribonuclease, RNase A family, 12 (non-active)
chr11_+_48510269 0.22 ENST00000446524.1
OR4A47
olfactory receptor, family 4, subfamily A, member 47
chr6_+_132873832 0.22 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr5_-_110848189 0.22 ENST00000296632.3
ENST00000512160.1
ENST00000509887.1
STARD4
StAR-related lipid transfer (START) domain containing 4
chr8_-_42698433 0.22 ENST00000345117.2
ENST00000254250.3
THAP1
THAP domain containing, apoptosis associated protein 1
chr7_-_77427676 0.22 ENST00000257663.3
TMEM60
transmembrane protein 60
chr8_-_42396185 0.21 ENST00000518717.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr4_-_153601136 0.21 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr11_+_112041253 0.21 ENST00000532612.1
AP002884.3
AP002884.3
chr5_-_54988448 0.21 ENST00000503817.1
ENST00000512595.1
SLC38A9
solute carrier family 38, member 9
chr4_-_130014609 0.21 ENST00000511426.1
SCLT1
sodium channel and clathrin linker 1
chr18_-_2982869 0.21 ENST00000584915.1
LPIN2
lipin 2
chr4_-_130014705 0.20 ENST00000503401.1
SCLT1
sodium channel and clathrin linker 1
chr2_+_27886330 0.20 ENST00000326019.6
SLC4A1AP
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr20_+_32150140 0.20 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr2_+_32502952 0.20 ENST00000238831.4
YIPF4
Yip1 domain family, member 4
chr18_-_19994830 0.20 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr14_+_23067146 0.20 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr3_+_51575596 0.20 ENST00000409535.2
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr3_-_186524144 0.20 ENST00000427785.1
RFC4
replication factor C (activator 1) 4, 37kDa
chr15_+_55700741 0.20 ENST00000569691.1
C15orf65
chromosome 15 open reading frame 65
chr1_-_74949033 0.19 ENST00000416014.2
LRRC53
leucine rich repeat containing 53
chr5_+_59783941 0.19 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr6_+_142468361 0.19 ENST00000367630.4
VTA1
vesicle (multivesicular body) trafficking 1
chr8_-_57026541 0.19 ENST00000311923.1
MOS
v-mos Moloney murine sarcoma viral oncogene homolog
chr1_+_109256067 0.19 ENST00000271311.2
FNDC7
fibronectin type III domain containing 7
chr15_+_36887069 0.19 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr5_-_137475071 0.18 ENST00000265191.2
NME5
NME/NM23 family member 5
chr13_+_73629107 0.18 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chrX_-_13835147 0.18 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr1_+_67632083 0.18 ENST00000347310.5
ENST00000371002.1
IL23R
interleukin 23 receptor
chr18_+_32556892 0.17 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr17_+_9479944 0.17 ENST00000396219.3
ENST00000352665.5
WDR16
WD repeat domain 16
chr10_+_95848824 0.17 ENST00000371385.3
ENST00000371375.1
PLCE1
phospholipase C, epsilon 1
chr7_+_63361201 0.17 ENST00000450544.1
RP11-340I6.8
RP11-340I6.8
chr14_+_20611895 0.17 ENST00000333629.1
OR4N5
olfactory receptor, family 4, subfamily N, member 5
chr4_+_146601356 0.17 ENST00000438731.1
ENST00000511965.1
C4orf51
chromosome 4 open reading frame 51
chr21_+_35736302 0.16 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr6_+_49467671 0.16 ENST00000371197.4
ENST00000545705.1
GLYATL3
glycine-N-acyltransferase-like 3
chr14_+_23025534 0.16 ENST00000557595.1
AE000662.92
Uncharacterized protein
chr1_+_170115142 0.16 ENST00000439373.2
METTL11B
methyltransferase like 11B
chr6_-_15548591 0.16 ENST00000509674.1
DTNBP1
dystrobrevin binding protein 1
chr9_-_107361788 0.16 ENST00000374779.2
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr12_+_21168630 0.15 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr18_-_69449517 0.15 ENST00000584810.1
RP11-723G8.2
Uncharacterized protein
chr17_+_3118915 0.15 ENST00000304094.1
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr7_-_104909435 0.15 ENST00000357311.3
SRPK2
SRSF protein kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 1.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.3 1.0 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.2 1.7 GO:1902896 terminal web assembly(GO:1902896)
0.2 0.7 GO:0010877 lipid transport involved in lipid storage(GO:0010877)
0.2 0.6 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2 0.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 1.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.2 1.3 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.1 0.6 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.8 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.1 1.5 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.6 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.7 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.3 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.3 GO:0061485 memory T cell proliferation(GO:0061485)
0.1 0.2 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.3 GO:0030821 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1 0.7 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.3 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.8 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.2 GO:1902102 metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.2 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.4 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.3 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0050955 thermoception(GO:0050955)
0.1 0.5 GO:2001023 regulation of response to drug(GO:2001023)
0.1 0.5 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 1.0 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 2.4 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.2 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 1.0 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 2.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.9 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950) negative regulation of myoblast fusion(GO:1901740)
0.0 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.1 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 1.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.3 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.0 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.0 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 2.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024) regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905031)
0.0 0.2 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 1.1 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.5 GO:0051180 vitamin transport(GO:0051180)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.1 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.7 GO:1990357 terminal web(GO:1990357)
0.1 1.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.9 GO:0071547 piP-body(GO:0071547)
0.1 1.2 GO:0016013 syntrophin complex(GO:0016013)
0.1 2.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.6 GO:0005827 polar microtubule(GO:0005827)
0.1 0.7 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.7 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0044305 calyx of Held(GO:0044305)
0.0 0.3 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.6 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.5 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.9 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 2.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 3.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.3 1.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.2 0.9 GO:0008431 vitamin E binding(GO:0008431)
0.2 1.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 1.5 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.6 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.8 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.4 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.1 0.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.2 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 1.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.7 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 2.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.3 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 5.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.7 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 1.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 2.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 1.2 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 2.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 2.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.9 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 3.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis