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Illumina Body Map 2, young vs old

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Results for HSF2

Z-value: 0.23

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Transcription factors associated with HSF2

Gene Symbol Gene ID Gene Info
HSF2
ENSG00000025156.8 heat shock transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF2hg19_v2_chr6_+_122720681_1227207130.373.9e-02Click!

Activity profile of HSF2 motif

Sorted Z-values of HSF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_103028638 2.79 ENST00000434483.1
PLP1
proteolipid protein 1
chr14_-_67859422 2.56 ENST00000556532.1
PLEK2
pleckstrin 2
chr9_-_91793675 2.52 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr4_+_76932326 2.45 ENST00000513353.1
ENST00000341029.5
ART3
ADP-ribosyltransferase 3
chr16_+_71392616 2.38 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
CALB2
calbindin 2
chr5_-_146833222 2.27 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr12_+_107078474 2.19 ENST00000552866.1
ENST00000229387.5
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr11_-_130298888 2.16 ENST00000257359.6
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr5_-_146833485 2.11 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr9_+_841690 2.06 ENST00000382276.3
DMRT1
doublesex and mab-3 related transcription factor 1
chr3_+_96533413 2.02 ENST00000470610.2
ENST00000389672.5
EPHA6
EPH receptor A6
chr1_-_168698433 1.99 ENST00000367817.3
DPT
dermatopontin
chr12_+_119616447 1.97 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr19_-_49250054 1.96 ENST00000602105.1
ENST00000332955.2
IZUMO1
izumo sperm-egg fusion 1
chr4_+_76932375 1.95 ENST00000513122.1
ART3
ADP-ribosyltransferase 3
chr7_-_80548493 1.94 ENST00000536800.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr15_-_58357866 1.92 ENST00000537372.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr5_-_112770674 1.89 ENST00000390666.3
TSSK1B
testis-specific serine kinase 1B
chr2_+_219824357 1.85 ENST00000302625.4
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr10_+_123970670 1.85 ENST00000496913.2
TACC2
transforming, acidic coiled-coil containing protein 2
chr11_+_27062502 1.80 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr17_-_39661849 1.77 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr6_+_151646800 1.67 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr11_-_111781610 1.65 ENST00000525823.1
CRYAB
crystallin, alpha B
chr11_+_71791803 1.65 ENST00000539271.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr11_-_111781554 1.63 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chr18_-_47376197 1.62 ENST00000592688.1
MYO5B
myosin VB
chr16_+_226658 1.60 ENST00000320868.5
ENST00000397797.1
HBA1
hemoglobin, alpha 1
chr2_-_152589670 1.58 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr4_-_6383594 1.57 ENST00000335585.5
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr14_+_38091270 1.56 ENST00000553443.1
TTC6
tetratricopeptide repeat domain 6
chr14_-_25479811 1.54 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr3_+_96533621 1.53 ENST00000542517.1
ENST00000506569.1
EPHA6
EPH receptor A6
chr17_-_74137374 1.53 ENST00000322957.6
FOXJ1
forkhead box J1
chr8_+_134125727 1.51 ENST00000521107.1
TG
thyroglobulin
chr11_-_111781454 1.51 ENST00000533280.1
CRYAB
crystallin, alpha B
chr7_-_4901625 1.51 ENST00000404991.1
PAPOLB
poly(A) polymerase beta (testis specific)
chr15_+_78556428 1.48 ENST00000394855.3
ENST00000489435.2
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr22_+_24577183 1.48 ENST00000358321.3
SUSD2
sushi domain containing 2
chr4_-_107957454 1.47 ENST00000285311.3
DKK2
dickkopf WNT signaling pathway inhibitor 2
chrX_-_102941596 1.47 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
MORF4L2
mortality factor 4 like 2
chr3_-_64673668 1.47 ENST00000498707.1
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chrX_-_51239425 1.44 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chrX_+_51075658 1.44 ENST00000356450.2
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr3_+_132843652 1.37 ENST00000508711.1
TMEM108
transmembrane protein 108
chr11_+_27062860 1.37 ENST00000528583.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr11_+_12695944 1.37 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr19_-_14629224 1.37 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr6_+_31795506 1.36 ENST00000375650.3
HSPA1B
heat shock 70kDa protein 1B
chr2_+_162272605 1.34 ENST00000389554.3
TBR1
T-box, brain, 1
chr11_+_12696102 1.31 ENST00000527636.1
ENST00000527376.1
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr4_+_77356248 1.27 ENST00000296043.6
SHROOM3
shroom family member 3
chr20_+_18794370 1.25 ENST00000377428.2
SCP2D1
SCP2 sterol-binding domain containing 1
chr6_-_123958141 1.24 ENST00000334268.4
TRDN
triadin
chr11_+_46316677 1.22 ENST00000534787.1
CREB3L1
cAMP responsive element binding protein 3-like 1
chr17_+_7608511 1.21 ENST00000226091.2
EFNB3
ephrin-B3
chrX_+_135230712 1.20 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr10_+_122216707 1.18 ENST00000427079.1
ENST00000541332.1
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr14_-_77889860 1.18 ENST00000555603.1
NOXRED1
NADP-dependent oxidoreductase domain containing 1
chr2_+_202937972 1.18 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chrY_-_20935572 1.18 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
HSFY2
heat shock transcription factor, Y linked 2
chr3_-_64673656 1.17 ENST00000459780.1
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr15_+_54305101 1.17 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
UNC13C
unc-13 homolog C (C. elegans)
chr17_-_60883993 1.14 ENST00000583803.1
ENST00000456609.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr1_+_18958008 1.14 ENST00000420770.2
ENST00000400661.3
PAX7
paired box 7
chr3_+_155755482 1.14 ENST00000472028.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr18_+_29171689 1.12 ENST00000237014.3
TTR
transthyretin
chr4_-_186877502 1.11 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2
sorbin and SH3 domain containing 2
chr3_+_158787041 1.09 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr5_+_79331164 1.02 ENST00000350881.2
THBS4
thrombospondin 4
chr14_+_32963433 1.01 ENST00000554410.1
AKAP6
A kinase (PRKA) anchor protein 6
chrY_+_20708557 1.01 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
HSFY1
heat shock transcription factor, Y-linked 1
chr19_-_49567124 1.01 ENST00000301411.3
NTF4
neurotrophin 4
chr1_-_184006829 1.00 ENST00000361927.4
COLGALT2
collagen beta(1-O)galactosyltransferase 2
chr15_+_42651691 1.00 ENST00000357568.3
ENST00000349748.3
ENST00000318023.7
ENST00000397163.3
CAPN3
calpain 3, (p94)
chr7_+_30960915 1.00 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1
aquaporin 1 (Colton blood group)
chr6_-_123957942 0.99 ENST00000398178.3
TRDN
triadin
chr18_-_812231 0.97 ENST00000314574.4
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr10_-_4285835 0.96 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr3_+_39509070 0.94 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr20_+_44746885 0.94 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chrX_+_135279179 0.93 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr6_-_123958051 0.92 ENST00000546248.1
TRDN
triadin
chr4_-_186877806 0.92 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr8_+_87878640 0.91 ENST00000518476.1
CNBD1
cyclic nucleotide binding domain containing 1
chrX_+_135278908 0.91 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr3_-_36781352 0.91 ENST00000416516.2
DCLK3
doublecortin-like kinase 3
chr14_-_102553371 0.90 ENST00000553585.1
ENST00000216281.8
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr10_+_18240834 0.89 ENST00000377371.3
ENST00000539911.1
SLC39A12
solute carrier family 39 (zinc transporter), member 12
chr19_+_6135646 0.89 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr17_-_76573465 0.87 ENST00000585328.1
ENST00000389840.5
DNAH17
dynein, axonemal, heavy chain 17
chr18_+_32173276 0.85 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr6_-_31782813 0.85 ENST00000375654.4
HSPA1L
heat shock 70kDa protein 1-like
chr9_-_34589734 0.84 ENST00000378980.3
CNTFR
ciliary neurotrophic factor receptor
chrX_-_128782722 0.84 ENST00000427399.1
APLN
apelin
chr7_+_75931861 0.84 ENST00000248553.6
HSPB1
heat shock 27kDa protein 1
chr1_-_102462565 0.84 ENST00000370103.4
OLFM3
olfactomedin 3
chr9_-_34710066 0.83 ENST00000378792.1
ENST00000259607.2
CCL21
chemokine (C-C motif) ligand 21
chr2_+_198365095 0.83 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr10_+_18240814 0.80 ENST00000377374.4
SLC39A12
solute carrier family 39 (zinc transporter), member 12
chr15_+_96869165 0.80 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr5_+_180581943 0.79 ENST00000328275.1
OR2V2
olfactory receptor, family 2, subfamily V, member 2
chr3_-_112360116 0.78 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr4_-_22517620 0.78 ENST00000502482.1
ENST00000334304.5
GPR125
G protein-coupled receptor 125
chr15_+_78556809 0.78 ENST00000343789.3
ENST00000394852.3
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr2_-_188419078 0.78 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr9_-_34589700 0.78 ENST00000351266.4
CNTFR
ciliary neurotrophic factor receptor
chr17_+_56315936 0.76 ENST00000543544.1
LPO
lactoperoxidase
chr15_+_36338242 0.75 ENST00000560056.1
RP11-684B21.1
RP11-684B21.1
chrX_+_101478829 0.75 ENST00000372763.1
ENST00000372758.1
NXF2
nuclear RNA export factor 2
chr10_+_18240753 0.75 ENST00000377369.2
SLC39A12
solute carrier family 39 (zinc transporter), member 12
chr11_+_1855645 0.75 ENST00000381968.3
ENST00000381978.3
SYT8
synaptotagmin VIII
chr13_+_46276441 0.74 ENST00000310521.1
ENST00000533564.1
SPERT
spermatid associated
chr10_+_120116527 0.73 ENST00000445161.1
LINC00867
long intergenic non-protein coding RNA 867
chr6_-_123958111 0.71 ENST00000542443.1
TRDN
triadin
chr1_-_184006611 0.69 ENST00000546159.1
COLGALT2
collagen beta(1-O)galactosyltransferase 2
chr8_-_120605194 0.69 ENST00000522167.1
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chrX_+_115301975 0.68 ENST00000371906.4
AGTR2
angiotensin II receptor, type 2
chr14_-_65409438 0.68 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr6_+_31783291 0.67 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
HSPA1A
heat shock 70kDa protein 1A
chr5_-_159739483 0.67 ENST00000519673.1
ENST00000541762.1
CCNJL
cyclin J-like
chr11_+_71791693 0.67 ENST00000289488.2
ENST00000447974.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr3_-_123411191 0.67 ENST00000354792.5
ENST00000508240.1
MYLK
myosin light chain kinase
chr22_+_36784632 0.66 ENST00000424761.1
RP4-633O19__A.1
RP4-633O19__A.1
chr9_+_91926103 0.64 ENST00000314355.6
CKS2
CDC28 protein kinase regulatory subunit 2
chr11_+_1856034 0.63 ENST00000341958.3
SYT8
synaptotagmin VIII
chr20_+_44746939 0.62 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr2_-_188419200 0.61 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chrX_-_101718085 0.61 ENST00000372750.1
ENST00000372752.1
NXF2B
nuclear RNA export factor 2B
chr17_-_71410794 0.61 ENST00000424778.1
SDK2
sidekick cell adhesion molecule 2
chr20_+_55904815 0.61 ENST00000371263.3
ENST00000345868.4
ENST00000371260.4
ENST00000418127.1
SPO11
SPO11 meiotic protein covalently bound to DSB
chr6_-_32122106 0.60 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr20_+_58203664 0.58 ENST00000541461.1
PHACTR3
phosphatase and actin regulator 3
chr14_+_101293687 0.57 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chr1_+_192544857 0.56 ENST00000367459.3
ENST00000469578.2
RGS1
regulator of G-protein signaling 1
chr19_-_49560987 0.56 ENST00000596965.1
CGB7
chorionic gonadotropin, beta polypeptide 7
chr17_-_56494908 0.55 ENST00000577716.1
RNF43
ring finger protein 43
chr17_-_56494882 0.54 ENST00000584437.1
RNF43
ring finger protein 43
chr1_-_228613026 0.53 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr4_+_184427235 0.53 ENST00000412117.1
ENST00000434682.2
ING2
inhibitor of growth family, member 2
chr11_+_66276550 0.52 ENST00000419755.3
CTD-3074O7.11
Bardet-Biedl syndrome 1 protein
chr13_-_31736132 0.52 ENST00000429785.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr19_-_46418033 0.51 ENST00000341294.2
NANOS2
nanos homolog 2 (Drosophila)
chr10_-_101673782 0.51 ENST00000422692.1
DNMBP
dynamin binding protein
chr14_-_57277178 0.51 ENST00000339475.5
ENST00000554559.1
ENST00000555804.1
OTX2
orthodenticle homeobox 2
chrX_+_106163626 0.50 ENST00000336803.1
CLDN2
claudin 2
chr6_+_44215603 0.49 ENST00000371554.1
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chrX_-_138304939 0.49 ENST00000448673.1
FGF13
fibroblast growth factor 13
chr7_-_14880892 0.49 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
DGKB
diacylglycerol kinase, beta 90kDa
chr12_+_55968199 0.48 ENST00000321688.1
OR2AP1
olfactory receptor, family 2, subfamily AP, member 1
chr1_-_248005254 0.48 ENST00000355784.2
OR11L1
olfactory receptor, family 11, subfamily L, member 1
chr10_-_1246300 0.48 ENST00000381310.3
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr7_-_150652924 0.48 ENST00000330883.4
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr3_-_48632593 0.48 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr13_+_24144796 0.47 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr14_-_52535712 0.47 ENST00000216286.5
ENST00000541773.1
NID2
nidogen 2 (osteonidogen)
chr19_-_55691472 0.46 ENST00000537500.1
SYT5
synaptotagmin V
chr11_-_89956227 0.46 ENST00000457199.2
ENST00000530765.1
CHORDC1
cysteine and histidine-rich domain (CHORD) containing 1
chr5_-_159739532 0.46 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL
cyclin J-like
chr17_-_39661947 0.44 ENST00000590425.1
KRT13
keratin 13
chr13_-_31736027 0.44 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1
heat shock 105kDa/110kDa protein 1
chr18_-_22804637 0.43 ENST00000577775.1
ZNF521
zinc finger protein 521
chr18_-_76738843 0.43 ENST00000575722.1
ENST00000583511.1
RP11-849I19.1
RP11-849I19.1
chr2_-_198364581 0.42 ENST00000428204.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr2_+_11674213 0.42 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chr12_+_2904102 0.41 ENST00000001008.4
FKBP4
FK506 binding protein 4, 59kDa
chr13_-_31736478 0.41 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr2_+_198365122 0.41 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr3_+_39509163 0.40 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chr14_-_23624511 0.40 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr9_+_109685630 0.39 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr19_-_14628645 0.38 ENST00000598235.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr7_+_120629653 0.38 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr11_-_122933043 0.38 ENST00000534624.1
ENST00000453788.2
ENST00000527387.1
HSPA8
heat shock 70kDa protein 8
chr14_+_89060749 0.36 ENST00000555900.1
ENST00000406216.3
ENST00000557737.1
ZC3H14
zinc finger CCCH-type containing 14
chr17_-_28661065 0.36 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr12_+_69979113 0.36 ENST00000299300.6
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr11_+_75273101 0.35 ENST00000533603.1
ENST00000358171.3
ENST00000526242.1
SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr14_-_65409502 0.34 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr12_-_43833515 0.33 ENST00000549670.1
ENST00000395541.2
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr7_+_132333553 0.33 ENST00000332558.4
AC009365.3
AC009365.3
chr13_+_24144509 0.33 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr11_+_75273246 0.31 ENST00000526397.1
ENST00000529643.1
ENST00000525492.1
ENST00000530284.1
ENST00000532356.1
ENST00000524558.1
SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr11_-_71791518 0.30 ENST00000537217.1
ENST00000366394.3
ENST00000358965.6
ENST00000546131.1
ENST00000543937.1
ENST00000368959.5
ENST00000541641.1
NUMA1
nuclear mitotic apparatus protein 1
chrX_-_102942961 0.30 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
MORF4L2
mortality factor 4 like 2
chr11_-_71791726 0.29 ENST00000393695.3
NUMA1
nuclear mitotic apparatus protein 1
chr14_+_89060739 0.29 ENST00000318308.6
ZC3H14
zinc finger CCCH-type containing 14
chr16_+_765092 0.28 ENST00000568223.2
METRN
meteorin, glial cell differentiation regulator
chr9_+_34989638 0.28 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr10_-_4285923 0.28 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr4_-_186877481 0.28 ENST00000444781.1
ENST00000432655.1
SORBS2
sorbin and SH3 domain containing 2
chr7_-_78400364 0.27 ENST00000535697.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_-_6453426 0.26 ENST00000545482.1
ACOT7
acyl-CoA thioesterase 7
chr7_+_23637763 0.26 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr12_+_69979210 0.25 ENST00000544368.2
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chrX_-_102943022 0.22 ENST00000433176.2
MORF4L2
mortality factor 4 like 2
chr1_+_27248203 0.22 ENST00000321265.5
NUDC
nudC nuclear distribution protein
chr1_-_6453399 0.22 ENST00000608083.1
ACOT7
acyl-CoA thioesterase 7
chr5_+_139505520 0.20 ENST00000333305.3
IGIP
IgA-inducing protein
chr20_+_4666882 0.19 ENST00000379440.4
ENST00000430350.2
PRNP
prion protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.6 1.9 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.6 0.6 GO:0007292 female gamete generation(GO:0007292)
0.5 1.5 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.5 2.0 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.5 2.9 GO:1901906 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.3 1.0 GO:0010160 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.3 1.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.3 1.6 GO:0007525 somatic muscle development(GO:0007525)
0.3 2.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.3 0.8 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.3 0.8 GO:0001754 eye photoreceptor cell differentiation(GO:0001754) photoreceptor cell differentiation(GO:0046530)
0.3 0.8 GO:0035759 mesangial cell-matrix adhesion(GO:0035759) regulation of dendritic cell dendrite assembly(GO:2000547)
0.3 0.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 0.8 GO:0018969 thiocyanate metabolic process(GO:0018969)
0.2 3.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 1.9 GO:0035799 ureter maturation(GO:0035799)
0.2 0.7 GO:0035566 negative regulation of icosanoid secretion(GO:0032304) regulation of metanephros size(GO:0035566)
0.2 1.3 GO:0021764 amygdala development(GO:0021764)
0.2 0.8 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.2 1.6 GO:0032439 endosome localization(GO:0032439)
0.2 2.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 0.8 GO:0009956 radial pattern formation(GO:0009956)
0.2 0.6 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.2 1.6 GO:0033590 response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018)
0.2 4.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 4.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 0.9 GO:0043335 protein unfolding(GO:0043335)
0.2 1.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.2 1.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 1.4 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.2 1.1 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.2 0.5 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.2 0.6 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2 3.0 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.2 0.5 GO:0002368 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.2 0.6 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 1.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 1.6 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 1.0 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 1.0 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 3.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.0 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.5 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 2.2 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 1.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 1.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 2.3 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 1.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 4.4 GO:0051764 actin crosslink formation(GO:0051764)
0.1 2.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.4 GO:0097106 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) postsynaptic density organization(GO:0097106)
0.1 1.5 GO:0015705 iodide transport(GO:0015705)
0.1 1.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 1.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 2.0 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 1.2 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.7 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1 0.5 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 1.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 4.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 1.3 GO:0045176 apical protein localization(GO:0045176)
0.1 0.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 1.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 2.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.6 GO:0015671 oxygen transport(GO:0015671)
0.1 1.1 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.6 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.5 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 2.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 2.7 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.6 GO:0009607 response to biotic stimulus(GO:0009607)
0.0 0.4 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 3.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 2.0 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.0 0.9 GO:0042026 protein refolding(GO:0042026)
0.0 0.8 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 1.0 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.9 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 1.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.6 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 1.5 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 3.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 2.4 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 2.6 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.5 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:1901631 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0035995 skeletal muscle myosin thick filament assembly(GO:0030241) detection of muscle stretch(GO:0035995)
0.0 0.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.5 GO:0051782 negative regulation of cell division(GO:0051782)
0.0 0.4 GO:0015695 organic cation transport(GO:0015695)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.4 2.7 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.4 1.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 1.0 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.3 1.6 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.3 3.9 GO:0030314 junctional membrane complex(GO:0030314)
0.3 4.8 GO:0097512 cardiac myofibril(GO:0097512)
0.2 1.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 1.6 GO:0043196 varicosity(GO:0043196)
0.1 1.1 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.2 GO:0044305 calyx of Held(GO:0044305)
0.1 0.8 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.5 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 1.6 GO:0045179 apical cortex(GO:0045179)
0.1 2.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.4 GO:1990769 proximal neuron projection(GO:1990769)
0.1 1.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 4.4 GO:0031941 filamentous actin(GO:0031941)
0.1 2.6 GO:0005921 gap junction(GO:0005921)
0.1 2.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.6 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 2.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 2.0 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.9 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 1.5 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.2 GO:1904115 axon cytoplasm(GO:1904115)
0.0 2.0 GO:0016235 aggresome(GO:0016235)
0.0 3.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 6.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 5.0 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 8.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 4.1 GO:0043209 myelin sheath(GO:0043209)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0014704 intercalated disc(GO:0014704)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 1.9 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.5 2.9 GO:0052847 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.4 4.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.4 1.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.3 1.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.3 4.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 2.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.3 0.8 GO:0036393 thiocyanate peroxidase activity(GO:0036393)
0.3 1.0 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.2 4.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 0.8 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.2 1.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 1.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 1.6 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.2 4.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 4.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 0.6 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.7 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 2.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.5 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 1.9 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.4 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 1.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.7 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 2.7 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 1.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.9 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.5 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 1.5 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 2.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 2.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 2.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 0.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 1.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 2.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.2 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.1 2.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 2.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 7.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 3.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.1 GO:0070402 NADPH binding(GO:0070402)
0.0 1.0 GO:0055103 titin binding(GO:0031432) ligase regulator activity(GO:0055103)
0.0 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 1.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:1903135 cupric ion binding(GO:1903135)
0.0 1.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 5.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 3.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.6 GO:0005179 hormone activity(GO:0005179)
0.0 1.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0043531 ADP binding(GO:0043531)
0.0 1.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.6 PID CD40 PATHWAY CD40/CD40L signaling
0.0 3.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 5.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 1.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.4 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 2.5 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.2 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 1.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 3.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination