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Illumina Body Map 2, young vs old

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Results for HSFY2

Z-value: 0.34

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Transcription factors associated with HSFY2

Gene Symbol Gene ID Gene Info
HSFY2
ENSG00000169953.11 heat shock transcription factor Y-linked 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSFY2hg19_v2_chrY_-_20935572_209356210.125.0e-01Click!

Activity profile of HSFY2 motif

Sorted Z-values of HSFY2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_95025661 1.48 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
PON1
PON3
paraoxonase 1
paraoxonase 3
chr4_+_81256871 1.47 ENST00000358105.3
ENST00000508675.1
C4orf22
chromosome 4 open reading frame 22
chr13_+_76378407 1.44 ENST00000447038.1
LMO7
LIM domain 7
chr10_-_101825151 1.37 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr2_-_152589670 1.36 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr3_+_186383741 1.35 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr13_+_76378357 1.33 ENST00000489941.2
ENST00000525373.1
LMO7
LIM domain 7
chr1_-_145076186 1.33 ENST00000369348.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_57431679 1.30 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
C8B
complement component 8, beta polypeptide
chr13_+_76378305 1.25 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr12_+_101962128 1.24 ENST00000550514.1
MYBPC1
myosin binding protein C, slow type
chr12_+_85430110 1.24 ENST00000393212.3
ENST00000393217.2
LRRIQ1
leucine-rich repeats and IQ motif containing 1
chr5_-_135290651 1.18 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chrX_+_46940254 1.10 ENST00000336169.3
RGN
regucalcin
chr1_-_57045228 1.09 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr19_+_50706866 1.07 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
MYH14
myosin, heavy chain 14, non-muscle
chr2_+_1418154 1.07 ENST00000423320.1
ENST00000382198.1
TPO
thyroid peroxidase
chr1_-_204121013 1.04 ENST00000367201.3
ETNK2
ethanolamine kinase 2
chr18_-_48351743 1.04 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
MRO
maestro
chr6_+_53976235 0.96 ENST00000502396.1
ENST00000358276.5
MLIP
muscular LMNA-interacting protein
chr8_-_120259055 0.94 ENST00000522828.1
ENST00000523307.1
ENST00000524129.1
ENST00000521048.1
ENST00000522187.1
RP11-4K16.2
RP11-4K16.2
chr4_-_100575781 0.90 ENST00000511828.1
RP11-766F14.2
Protein LOC285556
chr12_+_100897130 0.90 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr2_+_234959323 0.89 ENST00000373368.1
ENST00000168148.3
SPP2
secreted phosphoprotein 2, 24kDa
chr6_+_53976285 0.88 ENST00000514433.1
MLIP
muscular LMNA-interacting protein
chr6_+_53976211 0.87 ENST00000503951.1
MLIP
muscular LMNA-interacting protein
chr5_-_122372354 0.84 ENST00000306442.4
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr6_-_52705641 0.84 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr1_-_145075847 0.84 ENST00000530740.1
ENST00000369359.4
PDE4DIP
phosphodiesterase 4D interacting protein
chr10_+_5005598 0.84 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr1_+_145726886 0.81 ENST00000443667.1
PDZK1
PDZ domain containing 1
chr18_+_616711 0.80 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr15_-_45670924 0.80 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr15_+_84115868 0.78 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr13_-_46679185 0.77 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr6_+_163148161 0.77 ENST00000337019.3
ENST00000366889.2
PACRG
PARK2 co-regulated
chr9_+_131684027 0.77 ENST00000426694.1
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr9_+_131684562 0.75 ENST00000421063.2
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr6_+_46661575 0.75 ENST00000450697.1
TDRD6
tudor domain containing 6
chr4_+_152330390 0.75 ENST00000503146.1
ENST00000435205.1
FAM160A1
family with sequence similarity 160, member A1
chr19_-_55677920 0.75 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3
dynein, axonemal, assembly factor 3
chr21_+_41239243 0.75 ENST00000328619.5
PCP4
Purkinje cell protein 4
chr16_+_31494323 0.74 ENST00000569576.1
ENST00000330498.3
SLC5A2
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr11_+_112047087 0.74 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
BCO2
beta-carotene oxygenase 2
chr10_-_91403625 0.73 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
PANK1
pantothenate kinase 1
chr1_+_209859510 0.73 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr22_-_36013368 0.72 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr15_-_45694380 0.72 ENST00000561148.1
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr8_+_134029937 0.72 ENST00000518108.1
TG
thyroglobulin
chr17_+_7517264 0.72 ENST00000593717.1
ENST00000572182.1
ENST00000574539.1
ENST00000576728.1
ENST00000575314.1
ENST00000570547.1
ENST00000572262.1
ENST00000576478.1
AC007421.1
SHBG
AC007421.1
sex hormone-binding globulin
chr2_-_28113965 0.71 ENST00000302188.3
RBKS
ribokinase
chr6_+_8652370 0.70 ENST00000503668.1
HULC
hepatocellular carcinoma up-regulated long non-coding RNA
chr4_+_52917451 0.69 ENST00000295213.4
ENST00000419395.2
SPATA18
spermatogenesis associated 18
chr11_+_86667117 0.68 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr8_+_22224811 0.67 ENST00000381237.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr6_+_163148973 0.67 ENST00000366888.2
PACRG
PARK2 co-regulated
chr14_-_25519095 0.67 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr11_+_111126707 0.66 ENST00000280325.4
C11orf53
chromosome 11 open reading frame 53
chr5_-_35991486 0.66 ENST00000503189.1
UGT3A1
UDP glycosyltransferase 3 family, polypeptide A1
chr15_-_58571445 0.66 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr7_-_121784285 0.66 ENST00000417368.2
AASS
aminoadipate-semialdehyde synthase
chr10_+_35416223 0.65 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr6_+_125524785 0.65 ENST00000392482.2
TPD52L1
tumor protein D52-like 1
chrX_-_15511438 0.65 ENST00000380420.5
PIR
pirin (iron-binding nuclear protein)
chr4_+_187148556 0.65 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr1_-_213020991 0.65 ENST00000332912.3
C1orf227
chromosome 1 open reading frame 227
chrX_+_43515467 0.65 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr2_+_234959376 0.64 ENST00000425558.1
SPP2
secreted phosphoprotein 2, 24kDa
chr8_+_20811140 0.63 ENST00000523035.1
RP11-369E15.4
RP11-369E15.4
chr3_-_124653579 0.61 ENST00000478191.1
ENST00000311075.3
MUC13
mucin 13, cell surface associated
chr1_-_118727781 0.61 ENST00000336338.5
SPAG17
sperm associated antigen 17
chr1_+_111888890 0.61 ENST00000369738.4
PIFO
primary cilia formation
chr9_+_133971909 0.60 ENST00000247291.3
ENST00000372302.1
ENST00000372300.1
ENST00000372298.1
AIF1L
allograft inflammatory factor 1-like
chr3_-_165555200 0.60 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr18_-_61329118 0.59 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr1_-_169337176 0.59 ENST00000472647.1
ENST00000367811.3
NME7
NME/NM23 family member 7
chr14_+_94385235 0.59 ENST00000557719.1
ENST00000267594.5
FAM181A
family with sequence similarity 181, member A
chr8_-_133637624 0.59 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr6_-_46424599 0.58 ENST00000405162.1
RCAN2
regulator of calcineurin 2
chr10_+_7745232 0.58 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr19_-_38878632 0.58 ENST00000586599.1
ENST00000334928.6
ENST00000587676.1
GGN
gametogenetin
chr7_-_32338917 0.57 ENST00000396193.1
PDE1C
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr8_-_36636676 0.57 ENST00000524132.1
ENST00000519451.1
RP11-962G15.1
RP11-962G15.1
chr10_-_124459284 0.57 ENST00000432000.1
ENST00000329446.4
C10orf120
chromosome 10 open reading frame 120
chr12_+_75728419 0.57 ENST00000378695.4
ENST00000312442.2
GLIPR1L1
GLI pathogenesis-related 1 like 1
chr1_-_85358850 0.57 ENST00000370611.3
LPAR3
lysophosphatidic acid receptor 3
chr1_+_111889212 0.56 ENST00000369737.4
PIFO
primary cilia formation
chr20_-_3219828 0.55 ENST00000539553.2
SLC4A11
solute carrier family 4, sodium borate transporter, member 11
chr12_+_96337061 0.55 ENST00000266736.2
AMDHD1
amidohydrolase domain containing 1
chr16_-_20367584 0.54 ENST00000570689.1
UMOD
uromodulin
chr4_+_184826418 0.54 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr2_-_11810284 0.54 ENST00000306928.5
NTSR2
neurotensin receptor 2
chr10_+_7745303 0.54 ENST00000429820.1
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr7_-_50132801 0.53 ENST00000419417.1
ZPBP
zona pellucida binding protein
chr3_-_149293990 0.53 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr15_+_71389281 0.53 ENST00000355327.3
THSD4
thrombospondin, type I, domain containing 4
chr4_+_152330409 0.52 ENST00000513086.1
FAM160A1
family with sequence similarity 160, member A1
chr1_+_2938044 0.51 ENST00000378404.2
ACTRT2
actin-related protein T2
chrX_-_73072534 0.51 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr14_+_85996471 0.51 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr1_+_61542922 0.51 ENST00000407417.3
NFIA
nuclear factor I/A
chr9_+_71939488 0.51 ENST00000455972.1
FAM189A2
family with sequence similarity 189, member A2
chr16_-_20416053 0.51 ENST00000302451.4
PDILT
protein disulfide isomerase-like, testis expressed
chr21_+_44590245 0.51 ENST00000398132.1
CRYAA
crystallin, alpha A
chr17_+_11757333 0.50 ENST00000579703.1
DNAH9
dynein, axonemal, heavy chain 9
chr10_-_129691195 0.50 ENST00000368671.3
CLRN3
clarin 3
chr3_+_52821841 0.50 ENST00000405128.3
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr6_-_28321971 0.50 ENST00000396838.2
ENST00000426434.1
ENST00000434036.1
ENST00000439628.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr6_+_50061315 0.50 ENST00000415106.1
RP11-397G17.1
RP11-397G17.1
chr5_-_135290705 0.50 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr7_-_50132860 0.50 ENST00000046087.2
ZPBP
zona pellucida binding protein
chr11_+_101983176 0.49 ENST00000524575.1
YAP1
Yes-associated protein 1
chr1_-_84326618 0.49 ENST00000417565.1
RP11-475O6.1
RP11-475O6.1
chr18_+_616672 0.49 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr1_-_117210290 0.49 ENST00000369483.1
ENST00000369486.3
IGSF3
immunoglobulin superfamily, member 3
chrX_-_55020511 0.48 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr9_+_133971863 0.48 ENST00000372309.3
AIF1L
allograft inflammatory factor 1-like
chrX_-_33146477 0.48 ENST00000378677.2
DMD
dystrophin
chr3_+_100428188 0.48 ENST00000418917.2
ENST00000490574.1
TFG
TRK-fused gene
chr4_-_65275100 0.47 ENST00000509536.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr22_+_30792846 0.47 ENST00000312932.9
ENST00000428195.1
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr17_-_50237343 0.47 ENST00000575181.1
ENST00000570565.1
CA10
carbonic anhydrase X
chr8_-_17579726 0.47 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr9_-_34329198 0.47 ENST00000379166.2
ENST00000345050.2
KIF24
kinesin family member 24
chr4_-_89080003 0.47 ENST00000237612.3
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr3_+_100328433 0.47 ENST00000273352.3
GPR128
G protein-coupled receptor 128
chr5_+_42756903 0.46 ENST00000361970.5
ENST00000388827.4
CCDC152
coiled-coil domain containing 152
chr3_+_2933893 0.46 ENST00000397459.2
CNTN4
contactin 4
chr6_-_39902185 0.46 ENST00000373195.3
ENST00000308559.7
ENST00000373188.2
MOCS1
molybdenum cofactor synthesis 1
chr12_-_71533055 0.45 ENST00000552128.1
TSPAN8
tetraspanin 8
chr4_-_100356291 0.45 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr12_+_81331594 0.45 ENST00000549175.1
ACSS3
acyl-CoA synthetase short-chain family member 3
chr11_-_7695437 0.44 ENST00000533558.1
ENST00000527542.1
ENST00000531096.1
CYB5R2
cytochrome b5 reductase 2
chr19_+_3721719 0.44 ENST00000589378.1
ENST00000382008.3
TJP3
tight junction protein 3
chr14_+_39944025 0.43 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr11_-_108464465 0.43 ENST00000525344.1
EXPH5
exophilin 5
chr6_-_39399087 0.43 ENST00000229913.5
ENST00000541946.1
ENST00000394362.1
KIF6
kinesin family member 6
chr19_-_39466396 0.43 ENST00000292852.4
FBXO17
F-box protein 17
chr8_+_22601 0.43 ENST00000522481.3
ENST00000518652.1
AC144568.2
Uncharacterized protein
chr8_+_124864227 0.42 ENST00000522917.1
FER1L6
fer-1-like 6 (C. elegans)
chr8_+_1993152 0.42 ENST00000262113.4
MYOM2
myomesin 2
chr12_-_4758159 0.42 ENST00000545990.2
AKAP3
A kinase (PRKA) anchor protein 3
chr19_+_45349630 0.42 ENST00000252483.5
PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr16_+_48278178 0.42 ENST00000285737.4
ENST00000535754.1
LONP2
lon peptidase 2, peroxisomal
chr10_+_96522361 0.42 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr10_-_5046042 0.42 ENST00000421196.3
ENST00000455190.1
AKR1C2
aldo-keto reductase family 1, member C2
chr20_+_39969519 0.41 ENST00000373257.3
LPIN3
lipin 3
chr12_-_91572278 0.41 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN
decorin
chr14_-_25519317 0.41 ENST00000323944.5
STXBP6
syntaxin binding protein 6 (amisyn)
chr2_+_223536428 0.41 ENST00000446656.3
MOGAT1
monoacylglycerol O-acyltransferase 1
chr14_+_101293687 0.40 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chr11_-_66725837 0.40 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC
pyruvate carboxylase
chr19_-_19144243 0.40 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SUGP2
SURP and G patch domain containing 2
chr15_+_45694567 0.40 ENST00000559860.1
SPATA5L1
spermatogenesis associated 5-like 1
chr3_+_100428316 0.40 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TFG
TRK-fused gene
chr2_+_201170596 0.40 ENST00000439084.1
ENST00000409718.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr1_+_207226574 0.40 ENST00000367080.3
ENST00000367079.2
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr7_-_124405681 0.40 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr10_+_104614008 0.39 ENST00000369883.3
C10orf32
chromosome 10 open reading frame 32
chr8_-_101661887 0.39 ENST00000311812.2
SNX31
sorting nexin 31
chr9_+_470288 0.39 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr17_-_50237374 0.38 ENST00000442502.2
CA10
carbonic anhydrase X
chr11_+_34654011 0.38 ENST00000531794.1
EHF
ets homologous factor
chr15_+_67547113 0.38 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQCH
IQ motif containing H
chr7_-_82792215 0.38 ENST00000333891.9
ENST00000423517.2
PCLO
piccolo presynaptic cytomatrix protein
chr12_+_8309630 0.38 ENST00000396570.3
ZNF705A
zinc finger protein 705A
chr7_-_102789503 0.38 ENST00000465647.1
ENST00000418294.1
NAPEPLD
N-acyl phosphatidylethanolamine phospholipase D
chr3_+_174158732 0.38 ENST00000434257.1
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr7_-_102789629 0.37 ENST00000417955.1
ENST00000341533.4
ENST00000425379.1
NAPEPLD
N-acyl phosphatidylethanolamine phospholipase D
chr7_-_93520191 0.37 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr19_-_893200 0.37 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
MED16
mediator complex subunit 16
chr11_-_63376013 0.37 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr1_+_196788887 0.36 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr14_+_104394770 0.36 ENST00000409874.4
ENST00000339063.5
TDRD9
tudor domain containing 9
chr20_+_10199468 0.36 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr2_+_108863651 0.36 ENST00000329106.2
ENST00000376700.1
SULT1C3
sulfotransferase family, cytosolic, 1C, member 3
chr7_-_50633078 0.36 ENST00000444124.2
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr6_-_39902160 0.36 ENST00000340692.5
MOCS1
molybdenum cofactor synthesis 1
chr10_-_69455873 0.36 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr2_+_201170770 0.36 ENST00000409988.3
ENST00000409385.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr6_-_72129806 0.35 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
LINC00472
long intergenic non-protein coding RNA 472
chr2_+_233497931 0.35 ENST00000264059.3
EFHD1
EF-hand domain family, member D1
chr6_-_155635583 0.35 ENST00000367166.4
TFB1M
transcription factor B1, mitochondrial
chr11_-_72145669 0.35 ENST00000543042.1
ENST00000294053.3
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr14_-_21490958 0.35 ENST00000554104.1
NDRG2
NDRG family member 2
chr4_-_186317034 0.35 ENST00000505916.1
LRP2BP
LRP2 binding protein
chr14_+_85996507 0.34 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr10_-_70092671 0.34 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
PBLD
phenazine biosynthesis-like protein domain containing
chr11_-_72145426 0.34 ENST00000535990.1
ENST00000437826.2
ENST00000340729.5
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr6_-_47009996 0.34 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chr4_-_114438763 0.34 ENST00000509594.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr1_-_169455169 0.33 ENST00000367804.4
ENST00000236137.5
SLC19A2
solute carrier family 19 (thiamine transporter), member 2
chr18_-_59274139 0.33 ENST00000586949.1
RP11-879F14.2
RP11-879F14.2
chr15_+_84116106 0.33 ENST00000535412.1
ENST00000324537.5
SH3GL3
SH3-domain GRB2-like 3
chr20_+_33292068 0.33 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr2_-_97509729 0.33 ENST00000418232.1
ANKRD23
ankyrin repeat domain 23
chr19_+_50433476 0.33 ENST00000596658.1
ATF5
activating transcription factor 5
chr3_-_72897545 0.33 ENST00000325599.8
SHQ1
SHQ1, H/ACA ribonucleoprotein assembly factor
chr11_+_125034640 0.32 ENST00000542175.1
PKNOX2
PBX/knotted 1 homeobox 2
chr17_-_30470154 0.32 ENST00000398832.2
AC090616.2
Uncharacterized protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HSFY2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.4 1.5 GO:0006601 creatine biosynthetic process(GO:0006601)
0.4 1.5 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) phenylpropanoid catabolic process(GO:0046271)
0.3 1.4 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.3 1.4 GO:0030070 insulin processing(GO:0030070)
0.3 1.4 GO:0007525 somatic muscle development(GO:0007525)
0.2 0.7 GO:0042214 terpene metabolic process(GO:0042214)
0.2 0.9 GO:0034255 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 0.6 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 0.6 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 0.8 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 0.4 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.2 0.6 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.2 1.3 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.6 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.7 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 1.0 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.6 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 0.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.7 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.7 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.4 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.7 GO:0035900 response to isolation stress(GO:0035900)
0.1 0.8 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.7 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.5 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.3 GO:2000532 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532)
0.1 0.4 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.2 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 0.7 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.7 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 1.2 GO:0032324 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.3 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 1.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.2 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.7 GO:0035799 ureter maturation(GO:0035799)
0.1 0.3 GO:0090210 vitamin E metabolic process(GO:0042360) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.1 0.3 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.4 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.4 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 1.0 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.3 GO:0003175 tricuspid valve development(GO:0003175)
0.1 1.1 GO:0051601 exocyst localization(GO:0051601)
0.1 1.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.7 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.7 GO:0042908 xenobiotic transport(GO:0042908)
0.0 1.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.3 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.6 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 1.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.6 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.4 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.3 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.5 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 1.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.7 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 1.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.8 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0030638 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.2 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.5 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074) pulmonary vein morphogenesis(GO:0060577)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.5 GO:0072189 ureter development(GO:0072189)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.8 GO:0015879 carnitine transport(GO:0015879)
0.0 1.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.4 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.2 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.2 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:2000113 negative regulation of cellular macromolecule biosynthetic process(GO:2000113)
0.0 0.1 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 1.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 1.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 0.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.3 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 1.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.4 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 1.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.3 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0032990 cell part morphogenesis(GO:0032990) cell projection morphogenesis(GO:0048858)
0.0 0.6 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.7 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.1 GO:0051586 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.3 GO:0021930 olfactory bulb interneuron development(GO:0021891) cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.0 0.1 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.5 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.2 GO:0007059 chromosome segregation(GO:0007059)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.2 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.0 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.0 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.3 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.0 GO:0051350 negative regulation of lyase activity(GO:0051350)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.4 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868) L-cystine transport(GO:0015811)
0.0 0.1 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0042026 protein refolding(GO:0042026)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.2 0.6 GO:1990716 axonemal central apparatus(GO:1990716)
0.2 1.1 GO:0097513 myosin II filament(GO:0097513)
0.1 1.3 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.3 GO:0036457 keratohyalin granule(GO:0036457)
0.1 1.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.7 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 1.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.7 GO:0032982 myosin filament(GO:0032982)
0.1 0.4 GO:0005916 fascia adherens(GO:0005916)
0.1 0.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.2 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 1.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.8 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0071547 piP-body(GO:0071547)
0.0 0.5 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.9 GO:0036019 endolysosome(GO:0036019)
0.0 0.8 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.8 GO:0031970 organelle envelope lumen(GO:0031970)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.0 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.9 GO:0030118 clathrin coat(GO:0030118)
0.0 0.0 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.5 1.5 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2 0.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.9 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 0.8 GO:0008431 vitamin E binding(GO:0008431)
0.2 1.3 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.2 1.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.6 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 1.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.6 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.4 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.7 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.8 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.9 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.3 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 1.9 GO:0031432 titin binding(GO:0031432)
0.1 0.4 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.7 GO:0005497 androgen binding(GO:0005497)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.4 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.2 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.4 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.2 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.7 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.2 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.6 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 1.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.9 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.6 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.4 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 1.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 1.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 2.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.7 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 2.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.3 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.5 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.0 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0015186 L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0008035 high-density lipoprotein particle binding(GO:0008035)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 2.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 3.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha