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Illumina Body Map 2, young vs old

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Results for INSM1

Z-value: 0.22

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Transcription factors associated with INSM1

Gene Symbol Gene ID Gene Info
ENSG00000173404.3 INSM transcriptional repressor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
INSM1hg19_v2_chr20_+_20348740_203487650.421.7e-02Click!

Activity profile of INSM1 motif

Sorted Z-values of INSM1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_44657845 2.92 ENST00000243964.3
solute carrier family 12 (potassium/chloride transporter), member 5
chr9_-_37034028 2.85 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
paired box 5
chr8_-_120685608 2.56 ENST00000427067.2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr12_+_70760056 2.53 ENST00000258111.4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr17_-_42992856 2.45 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
glial fibrillary acidic protein
chr6_+_56820018 2.35 ENST00000370746.3
BEN domain containing 6
chr11_-_47400032 2.27 ENST00000533968.1
spleen focus forming virus (SFFV) proviral integration oncogene
chr6_+_56819773 2.27 ENST00000370750.2
BEN domain containing 6
chr20_+_44657807 2.07 ENST00000372315.1
solute carrier family 12 (potassium/chloride transporter), member 5
chr1_-_99470558 2.07 ENST00000370188.3
Lipid phosphate phosphatase-related protein type 5
chr1_-_99470368 2.06 ENST00000263177.4
Lipid phosphate phosphatase-related protein type 5
chr7_-_132262060 1.97 ENST00000359827.3
plexin A4
chr14_+_65879668 1.96 ENST00000553924.1
ENST00000358307.2
ENST00000557338.1
ENST00000554610.1
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr1_-_160040038 1.95 ENST00000368089.3
potassium inwardly-rectifying channel, subfamily J, member 10
chr8_+_28174649 1.87 ENST00000301908.3
prepronociceptin
chr7_+_86274145 1.86 ENST00000439827.1
ENST00000394720.2
ENST00000421579.1
glutamate receptor, metabotropic 3
chr11_-_47399942 1.73 ENST00000227163.4
spleen focus forming virus (SFFV) proviral integration oncogene
chr11_-_47400078 1.66 ENST00000378538.3
spleen focus forming virus (SFFV) proviral integration oncogene
chr3_+_14989186 1.66 ENST00000435454.1
ENST00000323373.6
nuclear receptor subfamily 2, group C, member 2
chr15_+_89182156 1.63 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr19_+_55795493 1.61 ENST00000309383.1
BR serine/threonine kinase 1
chr6_+_56820152 1.56 ENST00000370745.1
BEN domain containing 6
chr12_-_58131931 1.56 ENST00000547588.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chrX_+_37430822 1.53 ENST00000378621.3
ENST00000378619.3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr17_-_56606705 1.53 ENST00000317268.3
septin 4
chr2_-_73511559 1.51 ENST00000521871.1
F-box protein 41
chr11_-_47400062 1.50 ENST00000533030.1
spleen focus forming virus (SFFV) proviral integration oncogene
chr3_+_10857885 1.50 ENST00000254488.2
ENST00000454147.1
solute carrier family 6 (neurotransmitter transporter), member 11
chr3_-_147124547 1.47 ENST00000491672.1
ENST00000383075.3
Zic family member 4
chrX_-_153095945 1.44 ENST00000164640.4
PDZ domain containing 4
chr2_+_153191706 1.43 ENST00000288670.9
formin-like 2
chr8_+_28174496 1.42 ENST00000518479.1
prepronociceptin
chr14_-_103589246 1.42 ENST00000558224.1
ENST00000560742.1
long intergenic non-protein coding RNA 677
chr15_+_89181974 1.41 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr17_-_56606664 1.40 ENST00000580844.1
septin 4
chr17_-_42441204 1.39 ENST00000293443.7
family with sequence similarity 171, member A2
chr19_+_10196981 1.38 ENST00000591813.1
chromosome 19 open reading frame 66
chr7_+_86273952 1.37 ENST00000536043.1
glutamate receptor, metabotropic 3
chr15_+_27216297 1.36 ENST00000333743.6
gamma-aminobutyric acid (GABA) A receptor, gamma 3
chr17_-_37382105 1.35 ENST00000333461.5
SH3 and cysteine rich domain 2
chrX_-_153095813 1.34 ENST00000544474.1
PDZ domain containing 4
chr13_-_36705425 1.34 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
doublecortin-like kinase 1
chr15_+_89182178 1.32 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr17_-_36762095 1.31 ENST00000578925.1
ENST00000264659.7
SRC kinase signaling inhibitor 1
chr2_-_73511407 1.31 ENST00000520530.2
F-box protein 41
chr18_-_34409116 1.29 ENST00000334295.4
tubulin polyglutamylase complex subunit 2
chr18_-_34408902 1.29 ENST00000593035.1
ENST00000383056.3
ENST00000588909.1
ENST00000590337.1
tubulin polyglutamylase complex subunit 2
chr14_+_31343951 1.29 ENST00000556908.1
ENST00000555881.1
ENST00000460581.2
cochlin
chr8_-_11058847 1.27 ENST00000297303.4
ENST00000416569.2
XK, Kell blood group complex subunit-related family, member 6
chr12_+_49372251 1.27 ENST00000293549.3
wingless-type MMTV integration site family, member 1
chr17_-_56606639 1.26 ENST00000579371.1
septin 4
chr14_+_31343747 1.22 ENST00000216361.4
ENST00000396618.3
ENST00000475087.1
cochlin
chr10_+_48359344 1.22 ENST00000412534.1
ENST00000444585.1
zinc finger protein 488
chrX_+_118892545 1.20 ENST00000343905.3
sosondowah ankyrin repeat domain family member D
chr5_-_141030943 1.19 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCH and double SH3 domains 1
chr5_-_11904100 1.19 ENST00000359640.2
catenin (cadherin-associated protein), delta 2
chr9_+_137979506 1.18 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
olfactomedin 1
chr1_+_53098862 1.17 ENST00000517870.1
family with sequence similarity 159, member A
chr9_-_123691439 1.16 ENST00000540010.1
TNF receptor-associated factor 1
chrX_+_152907913 1.11 ENST00000370167.4
dual specificity phosphatase 9
chr14_+_65879437 1.11 ENST00000394585.1
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr2_-_72374948 1.09 ENST00000546307.1
ENST00000474509.1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr7_+_86273700 1.08 ENST00000546348.1
glutamate receptor, metabotropic 3
chrX_-_51812268 1.07 ENST00000486010.1
ENST00000497164.1
ENST00000360134.6
ENST00000485287.1
ENST00000335504.5
ENST00000431659.1
melanoma antigen family D, 4B
chr18_-_34408802 1.07 ENST00000590842.1
tubulin polyglutamylase complex subunit 2
chr10_-_103603523 1.07 ENST00000370046.1
Kv channel interacting protein 2
chr15_+_43803143 1.06 ENST00000382031.1
microtubule-associated protein 1A
chr1_-_38230738 1.04 ENST00000427468.2
ENST00000373048.4
ENST00000319637.6
EPH receptor A10
chrX_+_146993648 1.02 ENST00000370470.1
fragile X mental retardation 1
chr17_-_32906388 1.01 ENST00000357754.1
chromosome 17 open reading frame 102
chr2_-_27603582 0.96 ENST00000323703.6
ENST00000436006.1
zinc finger protein 513
chr19_+_10197463 0.96 ENST00000590378.1
ENST00000397881.3
chromosome 19 open reading frame 66
chr17_-_8868991 0.96 ENST00000447110.1
phosphoinositide-3-kinase, regulatory subunit 5
chr12_+_51985001 0.95 ENST00000354534.6
sodium channel, voltage gated, type VIII, alpha subunit
chr14_+_22314715 0.95 ENST00000390434.3
T cell receptor alpha variable 8-2
chr18_-_34408693 0.93 ENST00000587382.1
ENST00000589049.1
ENST00000587129.1
tubulin polyglutamylase complex subunit 2
chr2_+_232575128 0.93 ENST00000412128.1
prothymosin, alpha
chr5_-_11904152 0.93 ENST00000304623.8
ENST00000458100.2
catenin (cadherin-associated protein), delta 2
chr12_-_6960407 0.92 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
cell division cycle associated 3
chrX_+_51927919 0.91 ENST00000416960.1
melanoma antigen family D, 4
chrX_+_146993449 0.91 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
fragile X mental retardation 1
chr7_+_86273850 0.90 ENST00000454217.1
glutamate receptor, metabotropic 3
chr22_+_37447771 0.90 ENST00000402077.3
ENST00000403888.3
ENST00000456470.1
potassium channel tetramerization domain containing 17
chr6_+_22569784 0.90 ENST00000510882.2
hepatoma derived growth factor-like 1
chr15_+_90118723 0.89 ENST00000560985.1
TOPBP1-interacting checkpoint and replication regulator
chr5_-_60140009 0.89 ENST00000505959.1
ELOVL fatty acid elongase 7
chr14_+_96152754 0.88 ENST00000340722.7
T-cell leukemia/lymphoma 1B
chr6_-_29595779 0.88 ENST00000355973.3
ENST00000377012.4
gamma-aminobutyric acid (GABA) B receptor, 1
chr8_-_67525473 0.88 ENST00000522677.3
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr14_-_85996332 0.87 ENST00000380722.1
RP11-497E19.1
chr11_-_57417367 0.85 ENST00000534810.1
yippee-like 4 (Drosophila)
chr2_-_72375167 0.83 ENST00000001146.2
cytochrome P450, family 26, subfamily B, polypeptide 1
chr4_+_26322409 0.83 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
recombination signal binding protein for immunoglobulin kappa J region
chr15_-_77924689 0.83 ENST00000355300.6
leucine rich repeat and Ig domain containing 1
chr6_+_22569678 0.81 ENST00000230012.3
hepatoma derived growth factor-like 1
chr19_+_42817450 0.81 ENST00000301204.3
transmembrane protein 145
chrX_+_146993534 0.81 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
fragile X mental retardation 1
chrX_-_71525742 0.80 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr15_+_68924327 0.79 ENST00000543950.1
coronin, actin binding protein, 2B
chr11_-_57417405 0.79 ENST00000524669.1
ENST00000300022.3
yippee-like 4 (Drosophila)
chr5_-_60140089 0.79 ENST00000507047.1
ENST00000438340.1
ENST00000425382.1
ENST00000508821.1
ELOVL fatty acid elongase 7
chr17_+_19912640 0.78 ENST00000395527.4
ENST00000583482.2
ENST00000583528.1
ENST00000583463.1
sperm antigen with calponin homology and coiled-coil domains 1
chr4_+_619386 0.78 ENST00000496514.1
phosphodiesterase 6B, cGMP-specific, rod, beta
chr15_+_90118685 0.77 ENST00000268138.7
TOPBP1-interacting checkpoint and replication regulator
chr4_+_619347 0.76 ENST00000255622.6
phosphodiesterase 6B, cGMP-specific, rod, beta
chr4_+_174089951 0.76 ENST00000512285.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr14_-_51297360 0.73 ENST00000496749.1
ninein (GSK3B interacting protein)
chr1_-_1051455 0.73 ENST00000379339.1
ENST00000480643.1
ENST00000434641.1
ENST00000421241.2
chromosome 1 open reading frame 159
chr4_-_143767428 0.70 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr22_+_20104947 0.70 ENST00000402752.1
RAN binding protein 1
chr4_+_174089904 0.69 ENST00000265000.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr7_-_84816122 0.69 ENST00000444867.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr9_+_136243117 0.69 ENST00000426926.2
ENST00000371957.3
chromosome 9 open reading frame 96
chr11_-_40314652 0.69 ENST00000527150.1
leucine rich repeat containing 4C
chr1_-_205326161 0.69 ENST00000367156.3
ENST00000606887.1
ENST00000607173.1
kelch domain containing 8A
chr1_-_1051736 0.69 ENST00000448924.1
ENST00000294576.5
ENST00000437760.1
ENST00000462097.1
ENST00000475119.1
chromosome 1 open reading frame 159
chr1_-_205325850 0.69 ENST00000537168.1
kelch domain containing 8A
chr19_+_38893751 0.68 ENST00000588262.1
ENST00000252530.5
ENST00000343358.7
family with sequence similarity 98, member C
chr19_+_10196781 0.65 ENST00000253110.11
chromosome 19 open reading frame 66
chr8_-_67525524 0.64 ENST00000517885.1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr3_-_147124307 0.64 ENST00000463250.1
Zic family member 4
chr4_+_56815102 0.62 ENST00000257287.4
centrosomal protein 135kDa
chr13_-_36871886 0.62 ENST00000491049.2
ENST00000503173.1
ENST00000239860.6
ENST00000379862.2
ENST00000239859.7
ENST00000379864.2
ENST00000510088.1
ENST00000554962.1
ENST00000511166.1
coiled-coil domain containing 169
spermatogenesis and oogenesis specific basic helix-loop-helix 2
CCDC169-SOHLH2 readthrough
chr1_-_6557156 0.62 ENST00000537245.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr15_-_70388943 0.62 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr15_+_27216530 0.62 ENST00000555083.1
gamma-aminobutyric acid (GABA) A receptor, gamma 3
chr12_-_54779511 0.61 ENST00000551109.1
ENST00000546970.1
zinc finger protein 385A
chr1_-_205325698 0.60 ENST00000460687.1
kelch domain containing 8A
chr22_+_45064593 0.59 ENST00000432186.1
proline rich 5 (renal)
chr17_+_8869157 0.59 ENST00000585297.1
CTB-41I6.1
chr19_+_38879061 0.59 ENST00000587013.1
sprouty-related, EVH1 domain containing 3
chr11_+_124932955 0.59 ENST00000403796.2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr11_+_124932986 0.59 ENST00000407458.1
ENST00000298280.5
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr17_+_27369918 0.59 ENST00000323372.4
pipecolic acid oxidase
chr6_+_12749657 0.57 ENST00000406205.2
phosphatase and actin regulator 1
chr1_+_2398876 0.56 ENST00000449969.1
phospholipase C, eta 2
chr1_+_10490127 0.56 ENST00000602787.1
ENST00000602296.1
ENST00000400900.2
apoptosis-inducing, TAF9-like domain 1
APITD1-CORT readthrough
chr19_+_45394477 0.55 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr19_+_41284121 0.55 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
RAB4B, member RAS oncogene family
chr7_-_91509972 0.54 ENST00000425936.1
mitochondrial transcription termination factor
chr12_-_50101003 0.54 ENST00000550488.1
formin-like 3
chr19_-_38916839 0.53 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RAS guanyl releasing protein 4
chr1_-_205326022 0.52 ENST00000367155.3
kelch domain containing 8A
chr4_+_56814968 0.52 ENST00000422247.2
centrosomal protein 135kDa
chr9_-_98269699 0.52 ENST00000429896.2
patched 1
chr9_+_37650945 0.52 ENST00000377765.3
FERM and PDZ domain containing 1
chr1_-_205325994 0.52 ENST00000491471.1
kelch domain containing 8A
chr19_-_39340563 0.51 ENST00000601813.1
heterogeneous nuclear ribonucleoprotein L
chrX_+_69674943 0.51 ENST00000542398.1
discs, large homolog 3 (Drosophila)
chr22_+_20105259 0.50 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr8_-_116681686 0.50 ENST00000519815.1
trichorhinophalangeal syndrome I
chr3_-_15374033 0.50 ENST00000253688.5
ENST00000383791.3
SH3-domain binding protein 5 (BTK-associated)
chr12_-_76953513 0.48 ENST00000547540.1
oxysterol binding protein-like 8
chr17_+_27717415 0.47 ENST00000583121.1
ENST00000261716.3
TAO kinase 1
chr16_-_30134441 0.47 ENST00000395200.1
mitogen-activated protein kinase 3
chr3_+_185303962 0.47 ENST00000296257.5
SUMO1/sentrin/SMT3 specific peptidase 2
chr1_-_235116495 0.46 ENST00000549744.1
RP11-443B7.3
chr12_-_76953573 0.46 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
oxysterol binding protein-like 8
chr19_+_14142535 0.46 ENST00000263379.2
interleukin 27 receptor, alpha
chr14_+_62162258 0.46 ENST00000337138.4
ENST00000394997.1
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr5_+_60933634 0.45 ENST00000505642.1
chromosome 5 open reading frame 64
chr2_+_24272543 0.45 ENST00000380991.4
FK506 binding protein 1B, 12.6 kDa
chr5_-_175964366 0.45 ENST00000274811.4
ring finger protein 44
chr9_+_136243264 0.45 ENST00000371955.1
chromosome 9 open reading frame 96
chr1_-_154531095 0.43 ENST00000292211.4
ubiquitin-conjugating enzyme E2Q family member 1
chr19_-_55881741 0.43 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
interleukin 11
chr2_+_24272576 0.42 ENST00000380986.4
ENST00000452109.1
FK506 binding protein 1B, 12.6 kDa
chr10_-_103603568 0.42 ENST00000356640.2
Kv channel interacting protein 2
chr16_+_88704978 0.42 ENST00000244241.4
interleukin 17C
chr8_-_103136481 0.42 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
neurocalcin delta
chr4_-_164253738 0.41 ENST00000509586.1
ENST00000504391.1
ENST00000512819.1
neuropeptide Y receptor Y1
chr10_+_134258649 0.41 ENST00000392630.3
ENST00000321248.2
chromosome 10 open reading frame 91
chr9_+_140125385 0.40 ENST00000361134.2
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr18_+_34409069 0.40 ENST00000543923.1
ENST00000280020.5
ENST00000435985.2
ENST00000592521.1
ENST00000587139.1
KIAA1328
chr17_-_27277615 0.38 ENST00000583747.1
ENST00000584236.1
PHD finger protein 12
chr9_-_98269481 0.38 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
patched 1
chr19_+_42817527 0.38 ENST00000598766.1
transmembrane protein 145
chr9_-_130517522 0.37 ENST00000373274.3
ENST00000420366.1
SH2 domain containing 3C
chr22_+_20105012 0.36 ENST00000331821.3
ENST00000411892.1
RAN binding protein 1
chr6_-_33385902 0.36 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chr2_+_232575168 0.35 ENST00000440384.1
prothymosin, alpha
chr12_+_120105558 0.35 ENST00000229328.5
ENST00000541640.1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr1_-_85725316 0.34 ENST00000344356.5
ENST00000471115.1
chromosome 1 open reading frame 52
chr10_+_91061712 0.34 ENST00000371826.3
interferon-induced protein with tetratricopeptide repeats 2
chr9_+_140125209 0.34 ENST00000538474.1
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr10_-_103603677 0.34 ENST00000358038.3
Kv channel interacting protein 2
chr5_+_154238149 0.34 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CCR4-NOT transcription complex, subunit 8
chr14_+_73563735 0.34 ENST00000532192.1
RNA binding motif protein 25
chr11_+_124933191 0.33 ENST00000532000.1
ENST00000308074.4
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr16_-_30134524 0.33 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
mitogen-activated protein kinase 3
chr17_+_58755184 0.33 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr9_-_130517309 0.33 ENST00000414380.1
SH2 domain containing 3C
chr15_-_74045088 0.32 ENST00000569673.1
chromosome 15 open reading frame 59
chr17_+_37793318 0.32 ENST00000336308.5
StAR-related lipid transfer (START) domain containing 3
chr19_-_38916802 0.32 ENST00000587738.1
RAS guanyl releasing protein 4
chr11_+_66610883 0.32 ENST00000309657.3
ENST00000524506.1
Ras converting CAAX endopeptidase 1
chr2_+_152266392 0.32 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
RAP1 interacting factor homolog (yeast)
chr19_-_38916822 0.31 ENST00000586305.1
RAS guanyl releasing protein 4
chr3_+_185304059 0.31 ENST00000427465.2
SUMO1/sentrin/SMT3 specific peptidase 2
chr22_-_30695471 0.30 ENST00000434291.1
Uncharacterized protein

Network of associatons between targets according to the STRING database.

First level regulatory network of INSM1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0040040 thermosensory behavior(GO:0040040)
1.4 7.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.9 2.7 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.9 4.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.8 4.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.8 3.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.7 2.0 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.6 1.9 GO:1902811 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.4 1.3 GO:0061184 Spemann organizer formation(GO:0060061) positive regulation of dermatome development(GO:0061184)
0.4 1.2 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.3 5.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.3 2.0 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.3 0.8 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.3 1.8 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 1.6 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 0.9 GO:0010157 response to chlorate(GO:0010157)
0.2 1.7 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.2 2.6 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 1.2 GO:0019236 response to pheromone(GO:0019236)
0.1 1.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 2.9 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 1.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.2 GO:0003190 atrioventricular valve formation(GO:0003190)
0.1 0.5 GO:0021502 neural fold elevation formation(GO:0021502)
0.1 5.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 2.5 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 2.5 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.3 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.8 GO:0072554 blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.8 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.1 0.5 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 1.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.6 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.6 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 0.3 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1 0.7 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.9 GO:0022417 protein maturation by protein folding(GO:0022417)
0.1 1.5 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 0.4 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 2.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.8 GO:0035562 protein desumoylation(GO:0016926) regulation of DNA endoreduplication(GO:0032875) negative regulation of chromatin binding(GO:0035562) DNA endoreduplication(GO:0042023)
0.0 0.4 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 1.2 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.5 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.4 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.6 GO:0038203 TORC2 signaling(GO:0038203)
0.0 1.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 1.8 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.5 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 2.3 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 1.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.3 GO:0072719 cellular response to cisplatin(GO:0072719)
0.0 0.1 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.0 3.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 1.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 1.0 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.9 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.2 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 1.9 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.2 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.7 GO:0046710 GDP metabolic process(GO:0046710)
0.0 1.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.5 GO:0001525 angiogenesis(GO:0001525)
0.0 1.4 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 1.0 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.6 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 2.5 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:1902737 dendritic filopodium(GO:1902737)
0.2 1.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 0.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 4.2 GO:0097227 sperm annulus(GO:0097227)
0.1 2.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.9 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.2 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 4.4 GO:0015030 Cajal body(GO:0015030)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 4.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.5 GO:0001940 male pronucleus(GO:0001940)
0.0 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 5.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 4.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 3.3 GO:0043679 axon terminus(GO:0043679)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 2.1 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.5 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0008859 exoribonuclease II activity(GO:0008859)
0.9 5.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.8 3.1 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.6 7.2 GO:0051525 NFAT protein binding(GO:0051525)
0.5 2.6 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.5 3.3 GO:0001515 opioid peptide activity(GO:0001515)
0.4 2.7 GO:0034046 poly(G) binding(GO:0034046)
0.4 5.0 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 1.9 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 2.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 1.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 1.5 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 1.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 0.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 0.9 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 1.7 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.9 GO:0005119 smoothened binding(GO:0005119)
0.1 0.7 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 1.3 GO:0016015 morphogen activity(GO:0016015)
0.1 0.4 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 1.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.6 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.8 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 2.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 5.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.2 GO:0031996 thioesterase binding(GO:0031996)
0.1 2.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.3 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.8 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.7 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 2.0 GO:0004890 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.0 1.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.6 GO:0015288 porin activity(GO:0015288)
0.0 0.8 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.3 GO:0003696 satellite DNA binding(GO:0003696)
0.0 1.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0015293 symporter activity(GO:0015293)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 1.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 4.0 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 2.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 3.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 3.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 0.8 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 4.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 2.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.8 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 5.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 2.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 3.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription