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Illumina Body Map 2, young vs old

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Results for IRF2_STAT2_IRF8_IRF1

Z-value: 0.36

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Transcription factors associated with IRF2_STAT2_IRF8_IRF1

Gene Symbol Gene ID Gene Info
IRF2
ENSG00000168310.6 interferon regulatory factor 2
STAT2
ENSG00000170581.9 signal transducer and activator of transcription 2
IRF8
ENSG00000140968.6 interferon regulatory factor 8
IRF1
ENSG00000125347.9 interferon regulatory factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF1hg19_v2_chr5_-_131826457_1318265140.691.5e-05Click!
IRF2hg19_v2_chr4_-_185395672_1853957340.682.2e-05Click!
IRF8hg19_v2_chr16_+_85942594_859426350.672.8e-05Click!
STAT2hg19_v2_chr12_-_56753858_567539300.441.2e-02Click!

Activity profile of IRF2_STAT2_IRF8_IRF1 motif

Sorted Z-values of IRF2_STAT2_IRF8_IRF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_113416191 18.09 ENST00000342315.4
ENST00000392583.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr7_+_74188309 17.79 ENST00000289473.4
ENST00000433458.1
NCF1
neutrophil cytosolic factor 1
chrX_+_37639302 16.11 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr12_+_113416340 15.95 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr16_+_12058961 14.91 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr16_+_57023406 14.37 ENST00000262510.6
ENST00000308149.7
ENST00000436936.1
NLRC5
NLR family, CARD domain containing 5
chr12_+_113416265 13.81 ENST00000449768.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr7_+_150382781 13.46 ENST00000223293.5
ENST00000474605.1
GIMAP2
GTPase, IMAP family member 2
chr17_-_4643114 13.21 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chrX_+_37639264 13.12 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr16_-_67970990 12.91 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr21_+_42733870 12.73 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr1_+_158801095 12.70 ENST00000368141.4
MNDA
myeloid cell nuclear differentiation antigen
chr16_+_12059050 12.64 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr6_+_32821924 11.91 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr12_+_113376157 11.87 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr20_-_56195449 11.80 ENST00000541799.1
ZBP1
Z-DNA binding protein 1
chr3_+_187086120 11.44 ENST00000259030.2
RTP4
receptor (chemosensory) transporter protein 4
chr1_+_12227035 11.06 ENST00000376259.3
ENST00000536782.1
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr15_+_45003675 10.79 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
B2M
beta-2-microglobulin
chr6_+_26365443 10.77 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr1_+_79086088 10.66 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr3_-_49851313 10.54 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr8_+_27184320 10.51 ENST00000522517.1
PTK2B
protein tyrosine kinase 2 beta
chr4_-_76944621 10.49 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr12_+_94542459 10.10 ENST00000258526.4
PLXNC1
plexin C1
chr11_-_104905840 9.95 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr6_+_26365387 9.93 ENST00000532865.1
ENST00000530653.1
ENST00000527417.1
BTN3A2
butyrophilin, subfamily 3, member A2
chr2_+_7017796 9.92 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr22_+_39436862 9.80 ENST00000381565.2
ENST00000452957.2
APOBEC3F
APOBEC3G
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
chr6_+_6588902 9.78 ENST00000230568.4
LY86
lymphocyte antigen 86
chr1_+_948803 9.69 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr11_+_124932986 9.56 ENST00000407458.1
ENST00000298280.5
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr9_-_100881466 9.55 ENST00000341469.2
ENST00000342043.3
ENST00000375098.3
TRIM14
tripartite motif containing 14
chr11_+_124933191 9.46 ENST00000532000.1
ENST00000308074.4
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr17_-_4643161 9.38 ENST00000574412.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr14_-_67955426 9.37 ENST00000554480.1
TMEM229B
transmembrane protein 229B
chr3_-_27764190 9.25 ENST00000537516.1
EOMES
eomesodermin
chr20_-_56195525 9.15 ENST00000371173.3
ENST00000395822.3
ENST00000340462.4
ENST00000343535.4
ZBP1
Z-DNA binding protein 1
chr6_-_32821599 9.14 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_+_116782527 9.12 ENST00000368606.3
ENST00000368605.1
FAM26F
family with sequence similarity 26, member F
chr12_+_40618764 9.12 ENST00000343742.2
LRRK2
leucine-rich repeat kinase 2
chr6_+_26440700 9.01 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr4_-_169401628 8.76 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr2_-_7005785 8.74 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr13_-_43566301 8.68 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1
epithelial stromal interaction 1 (breast)
chr6_-_33281979 8.64 ENST00000426633.2
ENST00000467025.1
TAPBP
TAP binding protein (tapasin)
chr11_-_104916034 8.61 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16
caspase recruitment domain family, member 16
chr10_-_91174215 8.58 ENST00000371837.1
LIPA
lipase A, lysosomal acid, cholesterol esterase
chr6_+_32811861 8.52 ENST00000453426.1
TAPSAR1
TAP1 and PSMB8 antisense RNA 1
chr11_-_60720002 8.51 ENST00000538739.1
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr19_+_18284477 8.37 ENST00000407280.3
IFI30
interferon, gamma-inducible protein 30
chr16_-_11350036 8.28 ENST00000332029.2
SOCS1
suppressor of cytokine signaling 1
chr16_+_10972818 8.15 ENST00000576601.1
CIITA
class II, major histocompatibility complex, transactivator
chr1_-_89488510 8.09 ENST00000564665.1
ENST00000370481.4
GBP3
guanylate binding protein 3
chr16_+_85936295 8.07 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
IRF8
interferon regulatory factor 8
chr11_-_104972158 8.06 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr15_+_89182156 8.05 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr6_-_33282163 8.04 ENST00000434618.2
ENST00000456592.2
TAPBP
TAP binding protein (tapasin)
chr7_-_92777606 7.98 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr6_-_33282024 7.96 ENST00000475304.1
ENST00000489157.1
TAPBP
TAP binding protein (tapasin)
chr2_+_7005959 7.95 ENST00000442639.1
RSAD2
radical S-adenosyl methionine domain containing 2
chr8_-_79717163 7.82 ENST00000520269.1
IL7
interleukin 7
chr10_+_91087651 7.73 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr22_-_17700260 7.68 ENST00000399837.2
ENST00000543038.1
CECR1
cat eye syndrome chromosome region, candidate 1
chr6_+_26402517 7.65 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr15_+_89182178 7.56 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr11_+_5711010 7.53 ENST00000454828.1
TRIM22
tripartite motif containing 22
chr15_+_89181974 7.47 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr6_+_26402465 7.45 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr19_+_1077393 7.37 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr3_+_122399697 7.36 ENST00000494811.1
PARP14
poly (ADP-ribose) polymerase family, member 14
chr17_+_25958174 7.36 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr4_+_147096837 7.25 ENST00000296581.5
ENST00000502781.1
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr5_+_96211643 7.23 ENST00000437043.3
ENST00000510373.1
ERAP2
endoplasmic reticulum aminopeptidase 2
chr8_+_144640499 7.16 ENST00000525721.1
ENST00000534018.1
GSDMD
gasdermin D
chr6_+_32811885 7.08 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1
PSMB9
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr9_+_5450503 7.03 ENST00000381573.4
ENST00000381577.3
CD274
CD274 molecule
chr1_+_167599532 6.95 ENST00000537350.1
RCSD1
RCSD domain containing 1
chr1_+_158901329 6.93 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1
pyrin and HIN domain family, member 1
chr5_+_96212185 6.91 ENST00000379904.4
ERAP2
endoplasmic reticulum aminopeptidase 2
chr3_+_46449049 6.86 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
CCRL2
chemokine (C-C motif) receptor-like 2
chr11_+_60223312 6.82 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
MS4A1
membrane-spanning 4-domains, subfamily A, member 1
chr11_-_118095718 6.82 ENST00000526620.1
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr2_-_231084659 6.71 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110
SP110 nuclear body protein
chr4_+_100737954 6.66 ENST00000296414.7
ENST00000512369.1
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr14_-_67981916 6.56 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr1_-_161039753 6.56 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chrX_+_10031499 6.53 ENST00000454666.1
WWC3
WWC family member 3
chr4_-_169239921 6.51 ENST00000514995.1
ENST00000393743.3
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr2_+_202122826 6.39 ENST00000413726.1
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr19_-_18197799 6.39 ENST00000430026.3
ENST00000593993.2
IL12RB1
interleukin 12 receptor, beta 1
chr12_-_10022735 6.39 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr16_-_88851618 6.39 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr1_+_158979792 6.37 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr1_-_89531041 6.36 ENST00000370473.4
GBP1
guanylate binding protein 1, interferon-inducible
chr11_+_124932955 6.31 ENST00000403796.2
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr22_+_36044411 6.30 ENST00000409652.4
APOL6
apolipoprotein L, 6
chr2_-_231084820 6.29 ENST00000258382.5
ENST00000338556.3
SP110
SP110 nuclear body protein
chr8_+_144640477 6.29 ENST00000262580.4
GSDMD
gasdermin D
chr1_+_158149737 6.29 ENST00000368171.3
CD1D
CD1d molecule
chr3_-_172241250 6.27 ENST00000420541.2
ENST00000241261.2
TNFSF10
tumor necrosis factor (ligand) superfamily, member 10
chr3_+_63897605 6.16 ENST00000487717.1
ATXN7
ataxin 7
chr2_-_214014959 6.13 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
IKZF2
IKAROS family zinc finger 2 (Helios)
chr17_+_41363854 6.13 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr3_+_122283175 6.11 ENST00000383661.3
DTX3L
deltex 3-like (Drosophila)
chr2_-_231084617 6.06 ENST00000409815.2
SP110
SP110 nuclear body protein
chr11_+_71710648 6.06 ENST00000260049.5
IL18BP
interleukin 18 binding protein
chr15_+_75491213 6.06 ENST00000360639.2
C15orf39
chromosome 15 open reading frame 39
chr11_-_615942 6.05 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr11_+_60223225 6.00 ENST00000524807.1
ENST00000345732.4
MS4A1
membrane-spanning 4-domains, subfamily A, member 1
chr10_+_91174486 5.99 ENST00000416601.1
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr11_-_4414880 5.98 ENST00000254436.7
ENST00000543625.1
TRIM21
tripartite motif containing 21
chr2_+_163175394 5.98 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr6_-_32811771 5.93 ENST00000395339.3
ENST00000374882.3
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr10_+_134210672 5.93 ENST00000305233.5
ENST00000368609.4
PWWP2B
PWWP domain containing 2B
chr17_+_18380051 5.93 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
LGALS9C
lectin, galactoside-binding, soluble, 9C
chr7_+_140103842 5.90 ENST00000495590.1
ENST00000275874.5
ENST00000537763.1
RAB19
RAB19, member RAS oncogene family
chr16_-_31214051 5.87 ENST00000350605.4
PYCARD
PYD and CARD domain containing
chr11_-_57334732 5.86 ENST00000526659.1
ENST00000527022.1
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr8_-_79717750 5.86 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr11_+_71710973 5.83 ENST00000393707.4
IL18BP
interleukin 18 binding protein
chr11_-_118095801 5.82 ENST00000356289.5
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr15_-_50411412 5.77 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr5_-_96143602 5.75 ENST00000443439.2
ENST00000503921.1
ENST00000508227.1
ENST00000507154.1
ERAP1
endoplasmic reticulum aminopeptidase 1
chr17_-_33864772 5.68 ENST00000361112.4
SLFN12L
schlafen family member 12-like
chr3_+_122399444 5.62 ENST00000474629.2
PARP14
poly (ADP-ribose) polymerase family, member 14
chr12_+_113376249 5.61 ENST00000551007.1
ENST00000548514.1
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr5_-_39203093 5.58 ENST00000515010.1
FYB
FYN binding protein
chr11_-_60719213 5.53 ENST00000227880.3
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr12_-_49319265 5.51 ENST00000552878.1
ENST00000453172.2
FKBP11
FK506 binding protein 11, 19 kDa
chr13_+_108922228 5.51 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr17_+_47296865 5.48 ENST00000573347.1
ABI3
ABI family, member 3
chr1_-_161600990 5.48 ENST00000531221.1
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr12_+_113344811 5.47 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_-_53594227 5.43 ENST00000550743.2
ITGB7
integrin, beta 7
chrX_-_30595959 5.40 ENST00000378962.3
CXorf21
chromosome X open reading frame 21
chr2_-_89442621 5.37 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr4_-_185395672 5.34 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr19_-_7766991 5.32 ENST00000597921.1
ENST00000346664.5
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr1_+_158979680 5.31 ENST00000368131.4
ENST00000340979.6
IFI16
interferon, gamma-inducible protein 16
chr16_-_74734672 5.28 ENST00000306247.7
ENST00000575686.1
MLKL
mixed lineage kinase domain-like
chr2_-_191878681 5.26 ENST00000409465.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr1_-_161039647 5.26 ENST00000368013.3
ARHGAP30
Rho GTPase activating protein 30
chr2_+_90077680 5.17 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr22_-_36556821 5.15 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3
apolipoprotein L, 3
chr4_+_142557717 5.15 ENST00000320650.4
ENST00000296545.7
IL15
interleukin 15
chr6_-_31324943 5.14 ENST00000412585.2
ENST00000434333.1
HLA-B
major histocompatibility complex, class I, B
chr7_+_18535893 5.12 ENST00000432645.2
ENST00000441542.2
HDAC9
histone deacetylase 9
chr1_+_158979686 5.11 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr1_-_161600942 5.10 ENST00000421702.2
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr1_+_247579451 5.09 ENST00000391828.3
ENST00000366497.2
NLRP3
NLR family, pyrin domain containing 3
chr11_+_71709938 5.08 ENST00000393705.4
ENST00000337131.5
ENST00000531053.1
ENST00000404792.1
IL18BP
interleukin 18 binding protein
chr17_+_78234625 5.04 ENST00000508628.2
ENST00000582970.1
ENST00000456466.1
ENST00000319921.4
RNF213
ring finger protein 213
chr10_+_91061712 5.03 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr2_+_120687335 5.01 ENST00000544261.1
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr11_-_58980342 5.01 ENST00000361050.3
MPEG1
macrophage expressed 1
chr11_+_5646213 4.98 ENST00000429814.2
TRIM34
tripartite motif containing 34
chr12_-_49318715 4.95 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr2_+_202122703 4.95 ENST00000447616.1
ENST00000358485.4
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr3_+_46448648 4.94 ENST00000399036.3
CCRL2
chemokine (C-C motif) receptor-like 2
chr5_+_131746575 4.91 ENST00000337752.2
ENST00000378947.3
ENST00000407797.1
C5orf56
chromosome 5 open reading frame 56
chr4_-_122148620 4.91 ENST00000509841.1
TNIP3
TNFAIP3 interacting protein 3
chr1_+_27668505 4.90 ENST00000318074.5
SYTL1
synaptotagmin-like 1
chr14_+_86401039 4.89 ENST00000557195.1
CTD-2341M24.1
CTD-2341M24.1
chr7_+_134832808 4.82 ENST00000275767.3
TMEM140
transmembrane protein 140
chr11_+_1874200 4.82 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr15_-_80263506 4.80 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr10_+_91152303 4.80 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chrX_+_123095860 4.75 ENST00000428941.1
STAG2
stromal antigen 2
chr20_+_825275 4.72 ENST00000541082.1
FAM110A
family with sequence similarity 110, member A
chr2_-_191878874 4.72 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr1_-_27998689 4.66 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
IFI6
interferon, alpha-inducible protein 6
chr1_+_241695670 4.66 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr14_-_100841794 4.65 ENST00000556295.1
ENST00000554820.1
WARS
tryptophanyl-tRNA synthetase
chr11_-_615570 4.64 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr1_+_79115503 4.63 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr11_-_64764435 4.61 ENST00000534177.1
ENST00000301887.4
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr11_+_5710919 4.60 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr10_+_91174314 4.55 ENST00000371795.4
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chrX_+_123095546 4.46 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr16_-_28518153 4.43 ENST00000356897.1
IL27
interleukin 27
chr5_-_96143796 4.43 ENST00000296754.3
ERAP1
endoplasmic reticulum aminopeptidase 1
chr14_-_67981870 4.39 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr9_+_4985016 4.38 ENST00000539801.1
JAK2
Janus kinase 2
chr1_+_241695424 4.38 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_-_25291475 4.37 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr12_+_25205446 4.36 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr12_+_113344582 4.33 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr4_-_130014729 4.32 ENST00000281142.5
ENST00000434680.1
SCLT1
sodium channel and clathrin linker 1
chr17_+_6659153 4.30 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1
XIAP associated factor 1
chr12_-_32040123 4.24 ENST00000535163.1
RP11-428G5.5
RP11-428G5.5
chr14_-_65785502 4.24 ENST00000553754.1
CTD-2509G16.5
CTD-2509G16.5
chr1_-_161600822 4.21 ENST00000534776.1
ENST00000540048.1
FCGR3B
FCGR3A
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr4_-_130014532 4.20 ENST00000506368.1
ENST00000439369.2
ENST00000503215.1
SCLT1
sodium channel and clathrin linker 1
chr2_+_201994569 4.16 ENST00000457277.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr1_+_113217043 4.16 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr7_-_92747269 4.15 ENST00000446617.1
ENST00000379958.2
SAMD9
sterile alpha motif domain containing 9
chr2_-_55237484 4.07 ENST00000394609.2
RTN4
reticulon 4
chr1_+_113217073 4.04 ENST00000369645.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF2_STAT2_IRF8_IRF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 24.6 GO:0050822 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
5.8 29.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
4.7 18.9 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
4.7 52.0 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
4.6 23.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
4.3 47.8 GO:0018377 protein myristoylation(GO:0018377)
3.7 7.4 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
3.6 10.8 GO:0045062 extrathymic T cell selection(GO:0045062)
3.4 13.4 GO:0035915 pore formation in membrane of other organism(GO:0035915)
3.1 9.3 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
3.1 15.3 GO:0052056 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
3.0 9.1 GO:1903216 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
3.0 17.9 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
2.8 30.3 GO:0045345 positive regulation of MHC class I biosynthetic process(GO:0045345)
2.7 13.4 GO:0002636 positive regulation of germinal center formation(GO:0002636)
2.6 30.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.5 10.0 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
2.3 2.3 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
2.3 13.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
2.2 8.7 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
2.2 17.4 GO:0070383 DNA cytosine deamination(GO:0070383)
2.1 12.9 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
2.1 6.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
2.1 25.0 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
2.0 14.3 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
2.0 11.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
2.0 5.9 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
2.0 25.4 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
1.8 1.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.8 3.5 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
1.7 8.4 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
1.6 12.9 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
1.6 18.8 GO:0002252 immune effector process(GO:0002252) defense response to virus(GO:0051607)
1.5 1.5 GO:0035759 mesangial cell-matrix adhesion(GO:0035759)
1.5 6.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
1.5 17.8 GO:0060700 regulation of ribonuclease activity(GO:0060700)
1.5 5.9 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
1.5 8.7 GO:0019883 antigen processing and presentation of endogenous antigen(GO:0019883)
1.4 15.8 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
1.4 8.3 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
1.4 5.4 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
1.3 6.6 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
1.3 9.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
1.3 17.8 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
1.3 3.8 GO:1990108 protein linear deubiquitination(GO:1990108)
1.2 3.7 GO:1904596 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
1.2 9.7 GO:0071494 cellular response to UV-C(GO:0071494)
1.2 4.8 GO:0051097 negative regulation of helicase activity(GO:0051097)
1.2 14.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
1.2 25.4 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
1.2 35.8 GO:0072643 interferon-gamma secretion(GO:0072643)
1.2 15.0 GO:0035457 cellular response to interferon-alpha(GO:0035457)
1.1 11.0 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
1.1 5.4 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.1 4.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
1.1 5.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
1.0 5.2 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
1.0 3.0 GO:1900369 negative regulation of RNA interference(GO:1900369)
1.0 5.0 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.0 2.9 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.9 1.9 GO:0031296 B cell costimulation(GO:0031296)
0.9 2.7 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.9 21.6 GO:0010818 T cell chemotaxis(GO:0010818)
0.9 12.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.9 2.7 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.9 3.5 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.9 5.3 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.9 2.6 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.9 4.4 GO:1902724 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.9 5.2 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.8 1.7 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.8 12.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.8 1.7 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.8 3.3 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.8 7.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.8 1.6 GO:0043380 regulation of memory T cell differentiation(GO:0043380)
0.8 3.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.8 15.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.8 7.8 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.8 16.7 GO:0090050 peptidyl-lysine deacetylation(GO:0034983) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.7 2.2 GO:0021569 rhombomere 3 development(GO:0021569)
0.7 6.7 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.7 2.2 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.7 0.7 GO:0097102 endothelial tip cell fate specification(GO:0097102)
0.7 56.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.7 0.7 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.7 7.0 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.7 5.5 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.7 7.5 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.7 6.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.7 3.3 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.7 2.0 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.6 3.2 GO:0021546 rhombomere development(GO:0021546)
0.6 2.6 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.6 1.9 GO:0046968 peptide antigen transport(GO:0046968)
0.6 4.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.6 6.8 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.6 11.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.6 2.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.6 1.7 GO:0032911 endodermal cell fate determination(GO:0007493) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.6 8.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.6 17.5 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.5 2.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.5 2.2 GO:0072679 thymocyte migration(GO:0072679)
0.5 1.6 GO:0043317 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.5 2.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.5 10.4 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.5 1.6 GO:0061386 closure of optic fissure(GO:0061386)
0.5 3.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.5 3.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.5 1.5 GO:0097676 histone H3-K36 trimethylation(GO:0097198) histone H3-K36 dimethylation(GO:0097676)
0.5 1.5 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.5 3.5 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.5 51.4 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.5 12.3 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.5 3.9 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.5 2.4 GO:1990523 bone regeneration(GO:1990523)
0.5 1.0 GO:0034756 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.5 2.4 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.5 3.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.5 3.3 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.5 6.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.5 1.9 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.5 4.5 GO:0097338 response to clozapine(GO:0097338)
0.4 3.6 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.4 6.2 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.4 1.8 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.4 1.7 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501) peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.4 1.3 GO:0033037 polysaccharide localization(GO:0033037)
0.4 4.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.4 0.9 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.4 5.6 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.4 2.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.4 5.1 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.4 2.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.4 0.4 GO:1901026 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.4 1.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.4 11.7 GO:0002360 T cell lineage commitment(GO:0002360)
0.4 0.8 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.4 1.2 GO:0036451 cap mRNA methylation(GO:0036451)
0.4 32.5 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.4 4.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.4 2.3 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.4 2.3 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.4 1.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.4 2.7 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.4 2.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 1.9 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.4 0.7 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.4 0.4 GO:0050787 detoxification of mercury ion(GO:0050787)
0.4 2.6 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.4 1.8 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.4 2.2 GO:0070269 pyroptosis(GO:0070269)
0.4 3.6 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.4 3.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.4 9.5 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.3 2.7 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.3 4.0 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.3 1.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3 0.7 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.3 0.6 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.3 1.0 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.3 2.2 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.3 2.2 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.3 3.8 GO:0060022 hard palate development(GO:0060022)
0.3 14.3 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.3 7.0 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.3 2.7 GO:0048539 bone marrow development(GO:0048539)
0.3 9.2 GO:0045332 phospholipid translocation(GO:0045332)
0.3 2.3 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.3 2.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.3 2.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.3 2.6 GO:0060546 negative regulation of necroptotic process(GO:0060546) protein linear polyubiquitination(GO:0097039)
0.3 1.6 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.3 19.9 GO:0070206 protein trimerization(GO:0070206)
0.3 5.5 GO:0035456 response to interferon-beta(GO:0035456)
0.3 4.1 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.3 0.8 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.3 1.5 GO:0007296 vitellogenesis(GO:0007296)
0.3 1.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 0.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 1.0 GO:0060411 cardiac septum morphogenesis(GO:0060411)
0.2 0.7 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.2 0.5 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.2 12.0 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.2 1.2 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.2 0.9 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.2 10.5 GO:0010390 histone monoubiquitination(GO:0010390)
0.2 0.7 GO:0002384 hepatic immune response(GO:0002384)
0.2 0.7 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.2 4.0 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 0.7 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.2 2.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 0.4 GO:0036369 transcription factor catabolic process(GO:0036369)
0.2 2.9 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 1.9 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.2 1.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2 1.0 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 4.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.2 1.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.2 0.8 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.2 0.8 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 0.4 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.2 1.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 16.4 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.2 0.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 1.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.2 2.0 GO:0033227 dsRNA transport(GO:0033227)
0.2 0.7 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 3.5 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.2 3.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 8.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 2.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.2 1.1 GO:0010225 response to UV-C(GO:0010225)
0.2 1.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 2.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 2.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2 1.4 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2 1.4 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 1.4 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 1.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 0.5 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 1.4 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.2 3.6 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.2 4.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.2 9.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 4.2 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.2 3.0 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 1.2 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.2 2.0 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 0.7 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 2.8 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.2 0.8 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.2 1.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.2 0.3 GO:0010877 lipid transport involved in lipid storage(GO:0010877)
0.2 1.1 GO:1903772 virus maturation(GO:0019075) regulation of viral budding via host ESCRT complex(GO:1903772)
0.2 1.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 1.2 GO:0009615 response to virus(GO:0009615)
0.2 1.2 GO:0070475 rRNA base methylation(GO:0070475)
0.1 2.8 GO:0042832 defense response to protozoan(GO:0042832)
0.1 1.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 2.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 5.3 GO:0032479 regulation of type I interferon production(GO:0032479)
0.1 7.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.7 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.4 GO:0007518 myoblast fate determination(GO:0007518)
0.1 3.2 GO:0030336 negative regulation of cell migration(GO:0030336)
0.1 8.5 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.1 3.6 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.1 0.8 GO:0008217 regulation of blood pressure(GO:0008217)
0.1 1.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 3.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 1.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 10.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 1.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 4.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.4 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.4 GO:0060032 notochord regression(GO:0060032)
0.1 1.8 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 5.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.6 GO:0043686 co-translational protein modification(GO:0043686)
0.1 2.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 1.0 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.6 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 0.4 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) negative regulation of mitotic cell cycle DNA replication(GO:1903464) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 4.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.7 GO:0006308 DNA catabolic process(GO:0006308)
0.1 1.9 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.8 GO:0051510 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 2.5 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.9 GO:0070232 regulation of T cell apoptotic process(GO:0070232)
0.1 0.6 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.1 3.2 GO:0003094 glomerular filtration(GO:0003094)
0.1 4.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 0.2 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.1 2.9 GO:0036344 platelet morphogenesis(GO:0036344)
0.1 0.3 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.1 1.3 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 1.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 2.9 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 2.4 GO:0097264 self proteolysis(GO:0097264)
0.1 0.5 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 9.8 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 0.3 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 10.4 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.1 2.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.0 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 6.9 GO:0002456 T cell mediated immunity(GO:0002456)
0.1 15.6 GO:0006903 vesicle targeting(GO:0006903)
0.1 0.6 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 1.2 GO:0072718 response to cisplatin(GO:0072718)
0.1 1.1 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475)
0.1 1.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614) negative regulation of muscle hypertrophy(GO:0014741)
0.1 1.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 27.3 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.1 1.2 GO:0030091 protein repair(GO:0030091)
0.1 2.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.8 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 1.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.5 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 12.3 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.1 0.9 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 1.2 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.7 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 0.3 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.7 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 0.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 2.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.2 GO:1902950 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) regulation of dendritic spine maintenance(GO:1902950) negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 2.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.4 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 1.0 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.4 GO:0042335 cuticle development(GO:0042335)
0.1 0.6 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.1 5.4 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 0.6 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.5 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 1.7 GO:0015671 oxygen transport(GO:0015671)
0.1 0.5 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.1 0.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.5 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 1.0 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.8 GO:0009651 response to salt stress(GO:0009651)
0.1 0.4 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.1 1.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 1.2 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.1 0.6 GO:0045779 negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.1 1.5 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.1 0.8 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 0.8 GO:0014894 response to stimulus involved in regulation of muscle adaptation(GO:0014874) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 2.1 GO:0006275 regulation of DNA replication(GO:0006275)
0.1 1.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 3.3 GO:0006968 cellular defense response(GO:0006968)
0.1 0.6 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.5 GO:0035973 aggrephagy(GO:0035973)
0.1 0.2 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 1.3 GO:0097194 execution phase of apoptosis(GO:0097194)
0.1 0.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 0.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.2 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.5 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 1.1 GO:2000107 negative regulation of leukocyte apoptotic process(GO:2000107)
0.1 0.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 11.7 GO:0019083 viral transcription(GO:0019083)
0.1 7.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.8 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 1.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.7 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.5 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.7 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) V(D)J recombination(GO:0033151)
0.0 2.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 2.1 GO:0031529 ruffle organization(GO:0031529)
0.0 2.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0044857 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 3.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 9.5 GO:0015992 proton transport(GO:0015992)
0.0 0.6 GO:0015866 ADP transport(GO:0015866)
0.0 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.6 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.2 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.7 GO:0007379 segment specification(GO:0007379)
0.0 1.7 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.2 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.0 1.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.1 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.2 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.1 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.7 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 1.2 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 16.4 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.9 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 1.0 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.5 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.5 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.5 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 1.4 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.6 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.4 GO:0044259 collagen catabolic process(GO:0030574) collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.0 0.7 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.5 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.5 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.3 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.6 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.1 GO:0019541 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 1.5 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.3 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.4 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.7 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.6 GO:0016577 histone demethylation(GO:0016577)
0.0 0.6 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 1.0 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.1 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.8 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0030575 nuclear body organization(GO:0030575)
0.0 1.3 GO:0000725 recombinational repair(GO:0000725)
0.0 0.6 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:1904356 regulation of telomere maintenance via telomerase(GO:0032210) regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 41.6 GO:0042825 TAP complex(GO:0042825)
4.2 37.8 GO:1990111 spermatoproteasome complex(GO:1990111)
3.8 26.6 GO:0097179 protease inhibitor complex(GO:0097179)
3.3 9.8 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
2.8 8.4 GO:0042022 interleukin-12 receptor complex(GO:0042022)
2.6 12.8 GO:0031905 early endosome lumen(GO:0031905)
2.3 9.1 GO:0044753 amphisome(GO:0044753)
2.2 2.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
2.1 46.4 GO:0043020 NADPH oxidase complex(GO:0043020)
1.8 5.4 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
1.8 26.8 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
1.3 32.0 GO:0097342 ripoptosome(GO:0097342)
1.3 3.9 GO:0097679 other organism cytoplasm(GO:0097679)
1.3 7.6 GO:0008537 proteasome activator complex(GO:0008537)
1.2 10.6 GO:0043196 varicosity(GO:0043196)
1.1 5.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.1 10.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.8 15.2 GO:0071439 clathrin complex(GO:0071439)
0.8 3.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.7 3.4 GO:0036398 TCR signalosome(GO:0036398)
0.7 2.7 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.6 7.2 GO:0005688 U6 snRNP(GO:0005688)
0.5 14.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.5 3.0 GO:0044530 supraspliceosomal complex(GO:0044530)
0.5 1.4 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.5 10.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 2.6 GO:0071797 LUBAC complex(GO:0071797)
0.4 4.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.4 3.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.4 4.7 GO:0030870 Mre11 complex(GO:0030870)
0.4 31.9 GO:0015030 Cajal body(GO:0015030)
0.3 1.7 GO:0042611 MHC protein complex(GO:0042611) MHC class II protein complex(GO:0042613)
0.3 1.0 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.3 3.9 GO:0005642 annulate lamellae(GO:0005642)
0.3 1.9 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.3 0.6 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.3 2.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 1.8 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3 1.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.3 33.7 GO:0005811 lipid particle(GO:0005811)
0.3 3.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 1.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.2 42.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.2 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 3.6 GO:0044754 autolysosome(GO:0044754)
0.2 1.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 2.4 GO:0016589 NURF complex(GO:0016589)
0.2 1.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 1.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 7.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 4.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 1.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 25.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 2.3 GO:0032009 early phagosome(GO:0032009)
0.2 0.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 6.5 GO:0031528 microvillus membrane(GO:0031528)
0.2 2.6 GO:0042587 glycogen granule(GO:0042587)
0.2 18.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.2 1.6 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 6.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.2 2.2 GO:0044327 dendritic spine head(GO:0044327)
0.2 2.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 4.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 65.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 5.3 GO:0016580 Sin3 complex(GO:0016580)
0.2 0.5 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 1.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 7.0 GO:0030027 lamellipodium(GO:0030027)
0.1 2.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.7 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.4 GO:0031213 RSF complex(GO:0031213)
0.1 0.5 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 17.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.7 GO:0097165 nuclear stress granule(GO:0097165)
0.1 16.3 GO:0005643 nuclear pore(GO:0005643)
0.1 0.8 GO:0033391 chromatoid body(GO:0033391)
0.1 5.9 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.1 10.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 25.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.8 GO:0098791 Golgi subcompartment(GO:0098791)
0.1 1.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.2 GO:0042382 paraspeckles(GO:0042382)
0.1 0.7 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.4 GO:0071547 piP-body(GO:0071547)
0.1 1.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 3.8 GO:0042629 mast cell granule(GO:0042629)
0.1 6.1 GO:0001772 immunological synapse(GO:0001772)
0.1 1.5 GO:0032432 actin filament bundle(GO:0032432)
0.1 1.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.5 GO:0031105 septin complex(GO:0031105)
0.1 2.7 GO:0031143 pseudopodium(GO:0031143)
0.1 3.6 GO:0030057 desmosome(GO:0030057)
0.1 1.7 GO:0036020 endolysosome membrane(GO:0036020)
0.1 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 3.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.4 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.8 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.6 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.6 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 2.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 4.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 11.6 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.7 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 0.5 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 5.7 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 1.0 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 40.0 GO:0016607 nuclear speck(GO:0016607)
0.1 1.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 2.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 17.3 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 8.7 GO:0016605 PML body(GO:0016605)
0.1 3.9 GO:0099738 cell cortex region(GO:0099738)
0.1 3.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.4 GO:0005884 actin filament(GO:0005884)
0.1 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.7 GO:0070552 BRISC complex(GO:0070552)
0.1 5.2 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.4 GO:0030891 VCB complex(GO:0030891)
0.1 1.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.6 GO:0005579 membrane attack complex(GO:0005579)
0.1 2.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.9 GO:0032059 bleb(GO:0032059)
0.1 0.5 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.3 GO:0032437 cuticular plate(GO:0032437)
0.1 0.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 1.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.4 GO:0051233 spindle midzone(GO:0051233)
0.1 2.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 48.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 2.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 21.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 16.5 GO:0005769 early endosome(GO:0005769)
0.0 0.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 6.5 GO:0005903 brush border(GO:0005903)
0.0 8.3 GO:0001650 fibrillar center(GO:0001650)
0.0 8.9 GO:0010008 endosome membrane(GO:0010008)
0.0 0.7 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 2.6 GO:0032421 stereocilium bundle(GO:0032421)
0.0 16.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.9 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 3.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 4.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 3.7 GO:0072562 blood microparticle(GO:0072562)
0.0 5.5 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 10.3 GO:0016604 nuclear body(GO:0016604)
0.0 0.8 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 3.0 GO:0005938 cell cortex(GO:0005938)
0.0 2.8 GO:0035579 specific granule membrane(GO:0035579)
0.0 6.9 GO:0001726 ruffle(GO:0001726)
0.0 2.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 3.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 5.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.6 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 2.0 GO:0045202 synapse(GO:0045202)
0.0 0.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 4.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 11.9 GO:0005813 centrosome(GO:0005813)
0.0 10.1 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.8 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 4.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 83.5 GO:0005829 cytosol(GO:0005829)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.8 GO:0005925 focal adhesion(GO:0005925)
0.0 1.0 GO:0005768 endosome(GO:0005768)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 23.1 GO:0008859 exoribonuclease II activity(GO:0008859)
7.2 86.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
6.5 32.5 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
5.7 17.0 GO:0042007 interleukin-18 binding(GO:0042007)
4.8 24.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
3.5 10.4 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
3.3 13.2 GO:0046978 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
3.3 26.0 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
2.8 14.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
2.8 8.4 GO:0016517 interleukin-12 receptor activity(GO:0016517)
2.7 13.5 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
2.5 10.2 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
2.4 14.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
2.4 16.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
2.3 14.0 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
2.2 8.7 GO:0009041 uridylate kinase activity(GO:0009041)
2.0 11.8 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
2.0 5.9 GO:0032090 Pyrin domain binding(GO:0032090)
1.8 44.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
1.8 7.4 GO:0048030 disaccharide binding(GO:0048030)
1.4 9.5 GO:0031849 olfactory receptor binding(GO:0031849)
1.2 17.3 GO:0089720 caspase binding(GO:0089720)
1.2 3.7 GO:1904599 advanced glycation end-product binding(GO:1904599)
1.2 3.5 GO:0004531 deoxyribonuclease II activity(GO:0004531)
1.1 21.5 GO:0019864 IgG binding(GO:0019864)
1.1 8.6 GO:0004771 sterol esterase activity(GO:0004771)
1.1 10.7 GO:0042296 ISG15 transferase activity(GO:0042296)
1.1 4.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.1 10.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
1.0 13.4 GO:1901612 cardiolipin binding(GO:1901612)
1.0 32.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.0 1.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
1.0 9.0 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
1.0 5.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
1.0 2.9 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.9 28.7 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.9 2.7 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.9 3.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.8 7.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.7 9.7 GO:0031386 protein tag(GO:0031386)
0.7 30.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.7 34.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.6 1.9 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.6 6.3 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.6 5.5 GO:0070087 chromo shadow domain binding(GO:0070087)
0.6 1.8 GO:0098770 FBXO family protein binding(GO:0098770)
0.6 5.3 GO:0019863 IgE binding(GO:0019863)
0.6 3.5 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.6 27.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.6 13.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.5 2.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.5 4.3 GO:0031996 thioesterase binding(GO:0031996)
0.5 3.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.5 18.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.5 1.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.5 2.9 GO:0045569 TRAIL binding(GO:0045569)
0.5 16.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.5 2.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.5 2.7 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.4 2.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.4 2.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.4 3.3 GO:0071723 lipopeptide binding(GO:0071723)
0.4 1.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.4 5.3 GO:0051525 NFAT protein binding(GO:0051525)
0.4 1.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.4 2.3 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.4 14.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.4 2.7 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.4 2.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 15.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 2.0 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.3 5.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3 0.7 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.3 1.3 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.3 3.6 GO:0045159 myosin II binding(GO:0045159)
0.3 2.3 GO:0004977 melanocortin receptor activity(GO:0004977)
0.3 7.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.3 9.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 5.5 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3 4.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.3 1.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.3 2.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 9.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 1.2 GO:0004074 biliverdin reductase activity(GO:0004074)
0.3 3.8 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.3 3.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.3 5.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.3 1.7 GO:0030492 hemoglobin binding(GO:0030492)
0.3 10.2 GO:0000339 RNA cap binding(GO:0000339)
0.3 3.8 GO:0004000 adenosine deaminase activity(GO:0004000)
0.3 16.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.3 0.8 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.3 1.3 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.3 8.0 GO:0042605 peptide antigen binding(GO:0042605)
0.3 5.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 8.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 0.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.2 7.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 0.7 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.2 2.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 1.1 GO:0097001 ceramide binding(GO:0097001)
0.2 2.3 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 0.7 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.2 4.0 GO:0004568 chitinase activity(GO:0004568)
0.2 4.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 4.8 GO:0051400 BH domain binding(GO:0051400)
0.2 2.9 GO:0004985 opioid receptor activity(GO:0004985)
0.2 27.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 1.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.2 0.8 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.2 0.8 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.2 2.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.2 1.5 GO:0004064 arylesterase activity(GO:0004064)
0.2 5.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 2.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 4.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.4 GO:0046332 SMAD binding(GO:0046332)
0.2 1.2 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.2 1.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 0.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 1.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 3.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 7.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 3.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 1.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 0.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 1.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 0.5 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.2 1.1 GO:0000405 bubble DNA binding(GO:0000405)
0.2 4.1 GO:0032183 SUMO binding(GO:0032183)
0.2 1.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.2 1.7 GO:0035325 Toll-like receptor binding(GO:0035325)
0.1 0.7 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.1 7.9 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.4 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 1.8 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 9.6 GO:0019843 rRNA binding(GO:0019843)
0.1 34.3 GO:0004386 helicase activity(GO:0004386)
0.1 0.7 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.1 1.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 5.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.7 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 2.3 GO:0005123 death receptor binding(GO:0005123)
0.1 1.0 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.1 6.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.7 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 5.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 10.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 6.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.5 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 3.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 3.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 4.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.6 GO:1990460 leptin receptor binding(GO:1990460)
0.1 6.7 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.1 3.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.5 GO:0003680 AT DNA binding(GO:0003680)
0.1 2.1 GO:0005522 profilin binding(GO:0005522)
0.1 66.3 GO:0005525 GTP binding(GO:0005525)
0.1 2.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.7 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 3.9 GO:0017166 vinculin binding(GO:0017166)
0.1 2.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 4.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 6.8 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 3.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.8 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 15.7 GO:0003823 antigen binding(GO:0003823)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.5 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 0.4 GO:0034584 piRNA binding(GO:0034584)
0.1 2.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.4 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 1.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 2.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 3.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.9 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 2.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 1.0 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 1.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 11.9 GO:0001047 core promoter binding(GO:0001047)
0.1 1.2 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1 1.7 GO:0032452 histone demethylase activity(GO:0032452)
0.1 3.0 GO:0043394 proteoglycan binding(GO:0043394)
0.1 2.6 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.5 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 2.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 1.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 1.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.8 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 1.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.7 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 4.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.5 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 1.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.3 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.9 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 1.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 5.8 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.1 25.0 GO:0030246 carbohydrate binding(GO:0030246)
0.1 2.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 2.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 8.0 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 8.5 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.1 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 4.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 1.1 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 2.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.4 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.1 4.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 4.0 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 7.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.6 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1 2.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 4.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 2.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.0 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 1.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 2.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.7 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.5 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 1.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 6.8 GO:0042393 histone binding(GO:0042393)
0.0 0.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:1903135 cupric ion binding(GO:1903135)
0.0 1.0 GO:0070840 dynein complex binding(GO:0070840)
0.0 2.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.3 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 4.0 GO:0005319 lipid transporter activity(GO:0005319)
0.0 1.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 7.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 5.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 4.8 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.1 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.5 GO:0003924 GTPase activity(GO:0003924)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 3.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355) hexose transmembrane transporter activity(GO:0015149)
0.0 1.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.5 GO:0051117 ATPase binding(GO:0051117)
0.0 0.5 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.8 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 1.7 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters(GO:0016893)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 2.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 20.8 GO:0003723 RNA binding(GO:0003723)
0.0 0.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 14.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.8 31.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.6 5.7 PID IL27 PATHWAY IL27-mediated signaling events
0.5 17.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.5 48.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.5 54.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.3 10.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.3 16.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 1.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 12.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.3 5.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.3 14.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.3 12.5 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.2 8.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 5.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 21.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 14.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.2 3.0 PID IL23 PATHWAY IL23-mediated signaling events
0.2 19.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 0.7 ST STAT3 PATHWAY STAT3 Pathway
0.2 8.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 14.7 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 5.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 41.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 0.8 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 9.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 4.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 4.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 3.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 4.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 8.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 15.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 6.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 19.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 6.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 5.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 5.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 4.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 1.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 0.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 4.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.0 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.1 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.1 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 26.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
2.1 213.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
1.4 29.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.2 41.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
1.1 9.8 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.9 27.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.8 26.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.7 48.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.7 71.7 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.7 50.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.6 7.9 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.5 5.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.5 16.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.5 10.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.4 14.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.4 9.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.4 0.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.4 26.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.4 15.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.4 12.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.3 7.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3 33.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 5.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.2 10.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 5.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2 7.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 0.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 2.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.2 6.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 8.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 15.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 1.8 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
0.2 1.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 10.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 6.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 10.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 5.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 19.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 12.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 3.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 4.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 2.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 4.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 4.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 4.1 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 1.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 24.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 2.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 8.0 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.1 3.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 3.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 4.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 3.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 2.3 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 2.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 2.1 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 11.0 REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION Genes involved in Class I MHC mediated antigen processing & presentation
0.0 1.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 4.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 2.5 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 1.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 3.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 3.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 2.3 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 1.2 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 3.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression