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Illumina Body Map 2, young vs old

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Results for IRF7

Z-value: 0.04

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Transcription factors associated with IRF7

Gene Symbol Gene ID Gene Info
ENSG00000185507.15 interferon regulatory factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF7hg19_v2_chr11_-_615570_615728-0.541.6e-03Click!

Activity profile of IRF7 motif

Sorted Z-values of IRF7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91574142 9.56 ENST00000547937.1
decorin
chr2_-_151344172 6.87 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr6_-_46889694 6.47 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
G protein-coupled receptor 116
chr4_+_41614909 6.02 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr11_-_2160180 5.85 ENST00000381406.4
insulin-like growth factor 2 (somatomedin A)
chr12_+_19358228 5.68 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr1_-_85870177 5.64 ENST00000542148.1
dimethylarginine dimethylaminohydrolase 1
chr11_-_111794446 5.44 ENST00000527950.1
crystallin, alpha B
chr2_-_216240386 5.42 ENST00000438981.1
fibronectin 1
chr3_+_119316721 5.40 ENST00000488919.1
ENST00000495992.1
phospholipase A1 member A
chr4_-_186732048 5.34 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
sorbin and SH3 domain containing 2
chr1_+_162602244 5.17 ENST00000367922.3
ENST00000367921.3
discoidin domain receptor tyrosine kinase 2
chr4_-_152147579 5.03 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3 domain containing 19
chr14_+_94577074 4.96 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr13_+_110958124 4.94 ENST00000400163.2
collagen, type IV, alpha 2
chr5_+_140734570 4.85 ENST00000571252.1
protocadherin gamma subfamily A, 4
chr3_+_119316689 4.71 ENST00000273371.4
phospholipase A1 member A
chr4_-_87281196 4.66 ENST00000359221.3
mitogen-activated protein kinase 10
chr7_-_122526499 4.29 ENST00000412584.2
Ca++-dependent secretion activator 2
chr11_+_27062272 4.28 ENST00000529202.1
ENST00000533566.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr2_+_239756671 4.26 ENST00000448943.2
twist family bHLH transcription factor 2
chr12_-_91572278 4.23 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
decorin
chrX_-_34675391 4.19 ENST00000275954.3
transmembrane protein 47
chr4_+_41614720 4.14 ENST00000509277.1
LIM and calponin homology domains 1
chr9_+_6215799 4.12 ENST00000417746.2
ENST00000456383.2
interleukin 33
chr10_+_695888 4.06 ENST00000441152.2
proline rich 26
chr15_+_96875657 4.06 ENST00000559679.1
ENST00000394171.2
nuclear receptor subfamily 2, group F, member 2
chr5_+_32710736 4.05 ENST00000415685.2
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr4_-_138453606 4.03 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr8_+_39770803 4.01 ENST00000518237.1
indoleamine 2,3-dioxygenase 1
chr4_-_87281224 4.00 ENST00000395169.3
ENST00000395161.2
mitogen-activated protein kinase 10
chr12_-_22063787 3.98 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr4_+_113739244 3.93 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ankyrin 2, neuronal
chr4_-_164253738 3.91 ENST00000509586.1
ENST00000504391.1
ENST00000512819.1
neuropeptide Y receptor Y1
chr9_-_95186739 3.84 ENST00000375550.4
osteomodulin
chr3_+_186435065 3.84 ENST00000287611.2
ENST00000265023.4
kininogen 1
chr11_+_34643600 3.83 ENST00000530286.1
ENST00000533754.1
ets homologous factor
chr9_+_74764340 3.83 ENST00000376986.1
ENST00000358399.3
guanine deaminase
chr11_+_19799327 3.81 ENST00000540292.1
neuron navigator 2
chr7_-_16921601 3.80 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
anterior gradient 3
chr17_-_67057114 3.80 ENST00000370732.2
ATP-binding cassette, sub-family A (ABC1), member 9
chr10_+_123923205 3.63 ENST00000369004.3
ENST00000260733.3
transforming, acidic coiled-coil containing protein 2
chr11_+_77774897 3.60 ENST00000281030.2
thyroid hormone responsive
chr4_+_89300158 3.51 ENST00000502870.1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr17_-_67057203 3.48 ENST00000340001.4
ATP-binding cassette, sub-family A (ABC1), member 9
chr8_+_97597148 3.42 ENST00000521590.1
syndecan 2
chr1_-_207119738 3.40 ENST00000356495.4
polymeric immunoglobulin receptor
chr2_+_234526272 3.39 ENST00000373450.4
UDP glucuronosyltransferase 1 family, polypeptide A8
chr10_-_71169031 3.38 ENST00000373307.1
tachykinin receptor 2
chr20_+_56136136 3.36 ENST00000319441.4
ENST00000543666.1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr9_-_95298314 3.30 ENST00000344604.5
ENST00000375540.1
extracellular matrix protein 2, female organ and adipocyte specific
chr17_-_67057047 3.30 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ATP-binding cassette, sub-family A (ABC1), member 9
chr5_+_140625147 3.29 ENST00000231173.3
protocadherin beta 15
chr2_-_217560248 3.26 ENST00000233813.4
insulin-like growth factor binding protein 5
chr12_-_91576750 3.25 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
decorin
chr12_-_91573249 3.24 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr12_+_41831485 3.21 ENST00000539469.2
ENST00000298919.7
PDZ domain containing ring finger 4
chr7_-_122526799 3.19 ENST00000334010.7
ENST00000313070.7
Ca++-dependent secretion activator 2
chr6_+_118869452 3.16 ENST00000357525.5
phospholamban
chr15_+_80733570 3.14 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
aryl-hydrocarbon receptor nuclear translocator 2
chr1_+_82266053 3.11 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
latrophilin 2
chr9_-_119162885 3.08 ENST00000445861.2
PAPPA antisense RNA 1
chr3_+_186435137 3.08 ENST00000447445.1
kininogen 1
chr2_+_169658928 3.07 ENST00000317647.7
ENST00000445023.2
nitric oxide synthase trafficking
chr10_+_24498060 3.07 ENST00000376454.3
ENST00000376452.3
KIAA1217
chr3_-_112329110 3.05 ENST00000479368.1
coiled-coil domain containing 80
chr9_-_21187598 2.99 ENST00000421715.1
interferon, alpha 4
chr5_+_38845960 2.98 ENST00000502536.1
oncostatin M receptor
chr9_-_95298254 2.96 ENST00000444490.2
extracellular matrix protein 2, female organ and adipocyte specific
chr3_-_168865522 2.95 ENST00000464456.1
MDS1 and EVI1 complex locus
chr5_+_140749803 2.93 ENST00000576222.1
protocadherin gamma subfamily B, 3
chr1_-_114430169 2.92 ENST00000393316.3
BCL2-like 15
chr10_+_24497704 2.92 ENST00000376456.4
ENST00000458595.1
KIAA1217
chr12_+_7167980 2.91 ENST00000360817.5
ENST00000402681.3
complement component 1, s subcomponent
chr11_+_111789580 2.89 ENST00000278601.5
chromosome 11 open reading frame 52
chr5_+_140501581 2.89 ENST00000194152.1
protocadherin beta 4
chr2_-_152118352 2.88 ENST00000331426.5
RNA binding motif protein 43
chr4_-_138453559 2.88 ENST00000511115.1
protocadherin 18
chr12_-_91576561 2.87 ENST00000547568.2
ENST00000552962.1
decorin
chrX_+_48620147 2.81 ENST00000303227.6
glyoxalase domain containing 5
chrX_+_99899180 2.78 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr3_+_29322437 2.78 ENST00000434693.2
RNA binding motif, single stranded interacting protein 3
chr1_-_147232669 2.76 ENST00000369237.1
gap junction protein, alpha 5, 40kDa
chr15_+_96876340 2.76 ENST00000453270.2
nuclear receptor subfamily 2, group F, member 2
chr12_-_91573316 2.71 ENST00000393155.1
decorin
chr7_-_122526411 2.71 ENST00000449022.2
Ca++-dependent secretion activator 2
chr2_+_36923901 2.69 ENST00000457137.2
vitrin
chr12_-_59314246 2.65 ENST00000320743.3
leucine-rich repeats and immunoglobulin-like domains 3
chr11_-_119293872 2.62 ENST00000524970.1
Thy-1 cell surface antigen
chr2_+_234580525 2.61 ENST00000609637.1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr3_-_100565249 2.61 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI family, member 3 (NESH) binding protein
chr12_-_91573132 2.61 ENST00000550563.1
ENST00000546370.1
decorin
chr11_+_69455855 2.61 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr12_+_19358192 2.60 ENST00000538305.1
pleckstrin homology domain containing, family A member 5
chr7_+_55177416 2.56 ENST00000450046.1
ENST00000454757.2
epidermal growth factor receptor
chr8_+_85618155 2.55 ENST00000523850.1
ENST00000521376.1
RALY RNA binding protein-like
chr9_-_13175823 2.53 ENST00000545857.1
multiple PDZ domain protein
chr16_-_71598823 2.51 ENST00000566202.1
zinc finger protein 19
chr1_-_190446759 2.50 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr6_-_137366096 2.48 ENST00000316649.5
ENST00000367746.3
interleukin 20 receptor, alpha
chr17_+_28443819 2.46 ENST00000479218.2
nuclear speckle splicing regulatory protein 1
chr5_+_68788594 2.45 ENST00000396442.2
ENST00000380766.2
occludin
chr7_+_134576151 2.44 ENST00000393118.2
caldesmon 1
chr9_+_74764278 2.44 ENST00000238018.4
ENST00000376989.3
guanine deaminase
chr5_+_92919043 2.44 ENST00000327111.3
nuclear receptor subfamily 2, group F, member 1
chr4_-_187112626 2.41 ENST00000596414.1
Uncharacterized protein
chr7_-_111424462 2.37 ENST00000437129.1
dedicator of cytokinesis 4
chr12_-_10324716 2.36 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
oxidized low density lipoprotein (lectin-like) receptor 1
chrX_+_102883620 2.35 ENST00000372626.3
transcription elongation factor A (SII)-like 1
chr2_-_188419078 2.35 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr6_-_137365402 2.34 ENST00000541547.1
interleukin 20 receptor, alpha
chr14_-_35183755 2.33 ENST00000555765.1
cofilin 2 (muscle)
chr4_-_89951028 2.33 ENST00000506913.1
family with sequence similarity 13, member A
chr12_-_7245125 2.31 ENST00000542285.1
ENST00000540610.1
complement component 1, r subcomponent
chr10_+_18629628 2.31 ENST00000377329.4
calcium channel, voltage-dependent, beta 2 subunit
chr9_+_71986182 2.30 ENST00000303068.7
family with sequence similarity 189, member A2
chr5_+_38846101 2.29 ENST00000274276.3
oncostatin M receptor
chr10_-_115423792 2.29 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
nebulin-related anchoring protein
chr10_-_61495760 2.28 ENST00000395347.1
solute carrier family 16, member 9
chr6_-_53530474 2.28 ENST00000370905.3
kelch-like family member 31
chr11_+_46402583 2.27 ENST00000359803.3
midkine (neurite growth-promoting factor 2)
chr17_+_68100989 2.27 ENST00000585558.1
ENST00000392670.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr2_+_234580499 2.27 ENST00000354728.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr3_+_29322803 2.26 ENST00000396583.3
ENST00000383767.2
RNA binding motif, single stranded interacting protein 3
chr6_-_94129244 2.25 ENST00000369303.4
ENST00000369297.1
EPH receptor A7
chr17_-_67138015 2.24 ENST00000284425.2
ENST00000590645.1
ATP-binding cassette, sub-family A (ABC1), member 6
chr8_+_19171128 2.24 ENST00000265807.3
SH2 domain containing 4A
chr17_+_53343577 2.23 ENST00000573945.1
hepatic leukemia factor
chr3_-_149388682 2.22 ENST00000475579.1
WW domain containing transcription regulator 1
chr3_-_178865747 2.21 ENST00000435560.1
RP11-360P21.2
chrX_-_99891796 2.21 ENST00000373020.4
tetraspanin 6
chr12_+_12878829 2.20 ENST00000326765.6
apolipoprotein L domain containing 1
chr2_+_48796120 2.20 ENST00000394754.1
STON1-GTF2A1L readthrough
chr11_-_104769141 2.19 ENST00000508062.1
ENST00000422698.2
caspase 12 (gene/pseudogene)
chr6_-_137366163 2.19 ENST00000367748.1
interleukin 20 receptor, alpha
chr15_-_37393406 2.18 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr2_-_188419200 2.18 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr6_+_160693591 2.17 ENST00000419196.1
RP1-276N6.2
chr7_-_14029515 2.16 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ets variant 1
chr2_+_205410723 2.15 ENST00000358768.2
ENST00000351153.1
ENST00000349953.3
par-3 family cell polarity regulator beta
chr13_-_33780133 2.14 ENST00000399365.3
StAR-related lipid transfer (START) domain containing 13
chr7_-_93519471 2.14 ENST00000451238.1
tissue factor pathway inhibitor 2
chr12_-_71148413 2.13 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
protein tyrosine phosphatase, receptor type, R
chr3_+_29322851 2.13 ENST00000445033.1
RNA binding motif, single stranded interacting protein 3
chr8_+_17434689 2.13 ENST00000398074.3
platelet-derived growth factor receptor-like
chr14_-_54420133 2.13 ENST00000559501.1
ENST00000558984.1
bone morphogenetic protein 4
chr7_-_16505440 2.13 ENST00000307068.4
sclerostin domain containing 1
chr17_+_53343171 2.09 ENST00000430986.2
hepatic leukemia factor
chr14_-_35182994 2.08 ENST00000341223.3
cofilin 2 (muscle)
chr9_+_27109440 2.06 ENST00000519080.1
TEK tyrosine kinase, endothelial
chr5_-_41261540 2.06 ENST00000263413.3
complement component 6
chr12_-_7245152 2.06 ENST00000542220.2
complement component 1, r subcomponent
chr3_-_47950745 2.05 ENST00000429422.1
microtubule-associated protein 4
chr10_-_97321112 2.04 ENST00000607232.1
ENST00000371227.4
ENST00000371249.2
ENST00000371247.2
ENST00000371246.2
ENST00000393949.1
ENST00000353505.5
ENST00000347291.4
sorbin and SH3 domain containing 1
chr17_+_36584662 2.04 ENST00000431231.2
ENST00000437668.3
Rho GTPase activating protein 23
chr12_+_8850277 2.04 ENST00000539923.1
ENST00000537189.1
ribosomal modification protein rimK-like family member B
chr17_-_56492989 2.04 ENST00000583753.1
ring finger protein 43
chr12_-_28124903 2.03 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
parathyroid hormone-like hormone
chr5_+_140593509 2.02 ENST00000341948.4
protocadherin beta 13
chr3_-_151176497 2.02 ENST00000282466.3
immunoglobulin superfamily, member 10
chr10_-_75401500 2.01 ENST00000359322.4
myozenin 1
chr5_-_131630931 2.01 ENST00000431054.1
prolyl 4-hydroxylase, alpha polypeptide II
chr3_-_116163830 2.01 ENST00000333617.4
limbic system-associated membrane protein
chr3_-_114035026 1.99 ENST00000570269.1
RP11-553L6.5
chr3_-_28390298 1.98 ENST00000457172.1
5-azacytidine induced 2
chr21_+_17791648 1.98 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
long intergenic non-protein coding RNA 478
chrX_-_13835398 1.97 ENST00000475307.1
glycoprotein M6B
chr1_+_110453109 1.96 ENST00000525659.1
colony stimulating factor 1 (macrophage)
chr2_+_207804278 1.95 ENST00000272852.3
carboxypeptidase O
chr8_-_81787006 1.94 ENST00000327835.3
zinc finger protein 704
chr9_+_27109392 1.93 ENST00000406359.4
TEK tyrosine kinase, endothelial
chr3_-_28390120 1.91 ENST00000334100.6
5-azacytidine induced 2
chr16_-_21289627 1.91 ENST00000396023.2
ENST00000415987.2
crystallin, mu
chr15_+_71228826 1.91 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
leucine rich repeat containing 49
chr2_+_210444748 1.91 ENST00000392194.1
microtubule-associated protein 2
chr1_-_227505826 1.90 ENST00000334218.5
ENST00000366766.2
ENST00000366764.2
CDC42 binding protein kinase alpha (DMPK-like)
chr11_+_46402297 1.90 ENST00000405308.2
midkine (neurite growth-promoting factor 2)
chrX_-_31285042 1.89 ENST00000378680.2
ENST00000378723.3
dystrophin
chr3_+_100120441 1.89 ENST00000489752.1
leukemia NUP98 fusion partner 1
chrX_-_13835461 1.88 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr12_-_71148357 1.88 ENST00000378778.1
protein tyrosine phosphatase, receptor type, R
chr20_+_5892037 1.88 ENST00000378961.4
chromogranin B (secretogranin 1)
chr6_-_105585022 1.88 ENST00000314641.5
blood vessel epicardial substance
chr18_+_47088401 1.87 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
lipase, endothelial
chr15_-_99789736 1.85 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
tetratricopeptide repeat domain 23
chr2_+_153191706 1.85 ENST00000288670.9
formin-like 2
chr2_+_205410516 1.85 ENST00000406610.2
ENST00000462231.1
par-3 family cell polarity regulator beta
chr19_-_58485895 1.84 ENST00000314391.3
chromosome 19 open reading frame 18
chr13_+_102104980 1.83 ENST00000545560.2
integrin, beta-like 1 (with EGF-like repeat domains)
chr4_-_186732241 1.82 ENST00000421639.1
sorbin and SH3 domain containing 2
chr12_-_7245018 1.81 ENST00000543835.1
ENST00000535233.2
complement component 1, r subcomponent
chr18_-_10787140 1.81 ENST00000383408.2
piezo-type mechanosensitive ion channel component 2
chr17_-_76975925 1.80 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
lectin, galactoside-binding, soluble, 3 binding protein
chr1_+_176432298 1.80 ENST00000367661.3
ENST00000367662.3
pappalysin 2
chr4_+_15376165 1.79 ENST00000382383.3
ENST00000429690.1
C1q and tumor necrosis factor related protein 7
chr9_+_131684562 1.77 ENST00000421063.2
phytanoyl-CoA dioxygenase domain containing 1
chr17_+_28443799 1.76 ENST00000584423.1
ENST00000247026.5
nuclear speckle splicing regulatory protein 1
chr9_-_13279563 1.76 ENST00000541718.1
multiple PDZ domain protein
chr12_+_54519842 1.75 ENST00000508564.1
RP11-834C11.4
chr4_-_129491686 1.74 ENST00000514265.1
RP11-184M15.1

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0006147 guanine catabolic process(GO:0006147)
1.9 28.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.8 5.4 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
1.7 6.8 GO:0009956 radial pattern formation(GO:0009956)
1.3 6.4 GO:0060611 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
1.2 6.0 GO:0070980 biphenyl catabolic process(GO:0070980)
1.1 6.7 GO:0030421 defecation(GO:0030421)
1.1 5.4 GO:0036371 protein localization to T-tubule(GO:0036371)
1.1 3.3 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
1.1 3.2 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
1.0 10.2 GO:1990504 dense core granule exocytosis(GO:1990504)
1.0 4.0 GO:0036269 swimming behavior(GO:0036269)
0.9 2.8 GO:1990029 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.9 2.7 GO:0071314 cellular response to cocaine(GO:0071314)
0.9 2.6 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.8 3.4 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.8 2.5 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.8 2.4 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.8 6.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.8 3.1 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.7 2.9 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.7 1.4 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.7 5.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.7 6.3 GO:0021564 vagus nerve development(GO:0021564)
0.7 5.5 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.7 3.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.7 3.4 GO:0035106 negative regulation of luteinizing hormone secretion(GO:0033685) operant conditioning(GO:0035106)
0.7 5.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.7 2.6 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.7 3.3 GO:0001834 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.6 3.9 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.6 2.6 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.6 3.8 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.6 5.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.6 1.9 GO:0060931 sinoatrial node cell development(GO:0060931)
0.6 8.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.6 1.8 GO:1901254 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.6 1.8 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.6 4.8 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.6 1.8 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.6 3.5 GO:0051552 flavone metabolic process(GO:0051552)
0.6 1.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.6 1.7 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.6 4.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.5 5.9 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.5 2.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.5 2.7 GO:0032474 otolith morphogenesis(GO:0032474)
0.5 1.5 GO:0007493 endodermal cell fate determination(GO:0007493)
0.5 3.4 GO:0008218 bioluminescence(GO:0008218)
0.5 0.9 GO:0006533 aspartate catabolic process(GO:0006533)
0.5 10.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.4 4.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.4 1.8 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.4 5.6 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.4 1.7 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.4 1.3 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.4 1.7 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.4 2.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.4 2.0 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.4 2.4 GO:0061107 seminal vesicle development(GO:0061107)
0.4 0.8 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.4 1.6 GO:0072615 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.4 2.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.4 0.4 GO:0072011 glomerular endothelium development(GO:0072011)
0.4 10.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.4 1.5 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 1.5 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.4 1.5 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.4 1.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.4 1.1 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.4 4.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 1.4 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.3 4.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 1.2 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.3 1.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.3 2.0 GO:0051012 microtubule sliding(GO:0051012)
0.3 1.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 2.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.3 2.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.3 4.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.3 2.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.3 4.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 1.1 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) negative regulation of activation of membrane attack complex(GO:0001971)
0.3 0.8 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.3 1.1 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.3 1.6 GO:0015692 lead ion transport(GO:0015692)
0.3 0.8 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.3 0.8 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.3 3.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 2.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.2 1.0 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 1.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 8.6 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.2 0.7 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.2 0.9 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.2 8.5 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 4.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 2.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 3.8 GO:0097475 motor neuron migration(GO:0097475)
0.2 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 0.7 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 1.3 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 1.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 5.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 1.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 1.3 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.2 1.2 GO:0060005 vestibular reflex(GO:0060005)
0.2 0.6 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.2 2.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 1.3 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 4.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.2 1.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 2.0 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 0.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 1.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 0.5 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 0.9 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.2 1.3 GO:0035995 skeletal muscle myosin thick filament assembly(GO:0030241) detection of muscle stretch(GO:0035995)
0.2 0.4 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 0.7 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 0.2 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.2 0.7 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 1.0 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.2 1.7 GO:0070560 protein secretion by platelet(GO:0070560)
0.2 0.8 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.2 4.0 GO:0030157 pancreatic juice secretion(GO:0030157)
0.2 0.8 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.2 3.8 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 2.5 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 2.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 1.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 0.8 GO:0071874 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.2 0.8 GO:0033590 response to cobalamin(GO:0033590)
0.2 0.8 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.2 0.6 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.2 2.0 GO:0035641 locomotory exploration behavior(GO:0035641)
0.2 3.6 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 2.5 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 1.0 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 3.6 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.4 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.9 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 2.0 GO:0015705 iodide transport(GO:0015705)
0.1 1.0 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 2.3 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.1 1.5 GO:0070842 aggresome assembly(GO:0070842)
0.1 1.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 1.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.6 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.8 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 2.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 6.7 GO:0045124 regulation of bone resorption(GO:0045124)
0.1 1.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 2.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.4 GO:0050955 thermoception(GO:0050955)
0.1 2.6 GO:0097264 self proteolysis(GO:0097264)
0.1 2.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.5 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.5 GO:0007525 somatic muscle development(GO:0007525)
0.1 5.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 2.3 GO:0046415 urate metabolic process(GO:0046415)
0.1 1.7 GO:0070673 response to interleukin-18(GO:0070673)
0.1 6.7 GO:0010107 potassium ion import(GO:0010107)
0.1 0.3 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.8 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 0.8 GO:0071104 response to interleukin-9(GO:0071104)
0.1 1.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.8 GO:0070995 NADPH oxidation(GO:0070995)
0.1 2.0 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 1.2 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.1 2.1 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 1.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.8 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 17.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.5 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 1.0 GO:0021678 third ventricle development(GO:0021678)
0.1 2.0 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.8 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 1.0 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 0.3 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.1 0.2 GO:0046102 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.1 1.4 GO:0006600 creatine metabolic process(GO:0006600)
0.1 2.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 1.7 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.1 0.5 GO:0046541 saliva secretion(GO:0046541)
0.1 0.5 GO:1903772 virus maturation(GO:0019075) regulation of viral budding via host ESCRT complex(GO:1903772)
0.1 1.0 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 1.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.6 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
0.1 0.9 GO:1903671 negative regulation of sprouting angiogenesis(GO:1903671)
0.1 2.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 1.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 2.4 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.9 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 0.5 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 2.3 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 3.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.0 GO:0060065 uterus development(GO:0060065)
0.1 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.5 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 1.3 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.6 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 3.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 3.6 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.1 2.2 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 3.1 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)
0.1 1.6 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.2 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.6 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 3.6 GO:0006953 acute-phase response(GO:0006953)
0.1 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.6 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.4 GO:0048549 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.1 1.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.8 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.5 GO:0072189 ureter development(GO:0072189)
0.1 1.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 2.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 1.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.7 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.7 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 1.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 2.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 2.8 GO:0031529 ruffle organization(GO:0031529)
0.0 0.7 GO:0060044 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 9.0 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.6 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.4 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.5 GO:0015747 urate transport(GO:0015747)
0.0 1.3 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.6 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 3.9 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 9.1 GO:0045727 positive regulation of translation(GO:0045727)
0.0 1.9 GO:0019835 cytolysis(GO:0019835)
0.0 3.6 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 2.3 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 11.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.7 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.6 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 5.1 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 1.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 2.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.6 GO:0015866 ADP transport(GO:0015866)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 1.1 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.6 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.1 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 1.3 GO:0070207 protein homotrimerization(GO:0070207)
0.0 2.2 GO:0008542 visual learning(GO:0008542)
0.0 0.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.9 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 2.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 4.5 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.0 GO:0014904 myotube cell development(GO:0014904)
0.0 0.9 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0 0.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 1.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.6 GO:0008272 sulfate transport(GO:0008272)
0.0 3.8 GO:0008652 cellular amino acid biosynthetic process(GO:0008652)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 1.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.7 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.5 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.0 GO:0072716 response to actinomycin D(GO:0072716)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.5 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 1.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 8.0 GO:0006869 lipid transport(GO:0006869)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.3 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.0 1.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 1.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.7 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.9 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.5 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.6 GO:0019228 neuronal action potential(GO:0019228)
0.0 1.8 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 1.8 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 1.5 GO:0030449 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 0.4 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.1 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.1 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 1.0 GO:0030879 mammary gland development(GO:0030879)
0.0 0.9 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.5 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.5 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 28.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.8 5.3 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.9 6.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.9 2.6 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.7 22.6 GO:0005614 interstitial matrix(GO:0005614)
0.7 4.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.6 2.4 GO:0036027 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.6 1.8 GO:1902737 dendritic filopodium(GO:1902737)
0.6 6.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.6 1.7 GO:0005588 collagen type V trimer(GO:0005588)
0.5 6.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.5 1.6 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.5 4.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.4 1.3 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.4 4.0 GO:0005587 collagen type IV trimer(GO:0005587)
0.4 5.1 GO:0016013 syntrophin complex(GO:0016013)
0.4 2.3 GO:0005927 muscle tendon junction(GO:0005927)
0.3 4.5 GO:0005577 fibrinogen complex(GO:0005577)
0.3 2.0 GO:0005899 insulin receptor complex(GO:0005899)
0.3 4.0 GO:0030478 actin cap(GO:0030478)
0.3 10.1 GO:0002080 acrosomal membrane(GO:0002080)
0.3 1.6 GO:0070826 paraferritin complex(GO:0070826)
0.3 1.5 GO:0031673 H zone(GO:0031673)
0.3 6.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 4.4 GO:0097512 cardiac myofibril(GO:0097512)
0.2 2.4 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.7 GO:1990357 terminal web(GO:1990357)
0.2 3.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 1.0 GO:0005879 axonemal microtubule(GO:0005879)
0.2 0.8 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.2 5.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 2.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 6.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 4.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 1.3 GO:0043196 varicosity(GO:0043196)
0.1 3.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.4 GO:0005915 zonula adherens(GO:0005915)
0.1 5.4 GO:0043034 costamere(GO:0043034)
0.1 2.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 5.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.5 GO:0072534 perineuronal net(GO:0072534)
0.1 0.8 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.9 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 1.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 7.0 GO:0032420 stereocilium(GO:0032420)
0.1 1.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 2.4 GO:0048786 presynaptic active zone(GO:0048786)
0.1 3.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.8 GO:0005922 connexon complex(GO:0005922)
0.1 4.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.9 GO:0044305 calyx of Held(GO:0044305)
0.1 0.9 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 2.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 17.3 GO:0030018 Z disc(GO:0030018)
0.1 9.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 2.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 3.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.3 GO:0036038 MKS complex(GO:0036038)
0.1 1.2 GO:0008091 spectrin(GO:0008091)
0.1 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.5 GO:0043203 axon hillock(GO:0043203)
0.1 1.0 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 2.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 4.6 GO:0016235 aggresome(GO:0016235)
0.1 0.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.0 GO:0097433 dense body(GO:0097433)
0.1 8.0 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 8.2 GO:0042734 presynaptic membrane(GO:0042734)
0.1 10.4 GO:0005923 bicellular tight junction(GO:0005923)
0.1 2.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.6 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.4 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.8 GO:0032059 bleb(GO:0032059)
0.0 5.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 3.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.3 GO:0071437 invadopodium(GO:0071437)
0.0 1.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.6 GO:0032590 dendrite membrane(GO:0032590)
0.0 3.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 4.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.0 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.4 GO:0033391 chromatoid body(GO:0033391)
0.0 0.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 1.2 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 4.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 1.3 GO:0008305 integrin complex(GO:0008305)
0.0 0.8 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 1.7 GO:0098793 presynapse(GO:0098793)
0.0 4.2 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 2.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.2 GO:0042383 sarcolemma(GO:0042383)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 6.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0031595 proteasome regulatory particle, lid subcomplex(GO:0008541) nuclear proteasome complex(GO:0031595)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0014704 intercalated disc(GO:0014704)
0.0 0.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.0 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0008892 guanine deaminase activity(GO:0008892)
1.4 10.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
1.4 8.5 GO:0042015 interleukin-20 binding(GO:0042015)
1.4 4.2 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
1.3 6.3 GO:0070052 collagen V binding(GO:0070052)
1.2 3.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.1 3.3 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.1 4.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.0 4.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
1.0 4.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
1.0 3.9 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
1.0 3.9 GO:0001601 peptide YY receptor activity(GO:0001601)
0.9 2.8 GO:0086078 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.9 5.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.8 5.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.8 6.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.7 8.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.7 9.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.7 3.4 GO:0004995 tachykinin receptor activity(GO:0004995)
0.5 2.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.5 4.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.5 1.5 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.5 1.9 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.5 2.3 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.5 1.4 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.4 14.2 GO:0002162 dystroglycan binding(GO:0002162)
0.4 3.0 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.4 1.3 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.4 8.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.4 1.6 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.4 1.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.4 3.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.4 18.8 GO:0001972 retinoic acid binding(GO:0001972)
0.4 1.5 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.4 1.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.3 5.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 2.0 GO:0051373 FATZ binding(GO:0051373)
0.3 5.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 26.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 2.1 GO:0098821 BMP receptor activity(GO:0098821)
0.3 1.6 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.3 4.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 1.8 GO:0034046 poly(G) binding(GO:0034046)
0.3 3.9 GO:0070700 BMP receptor binding(GO:0070700)
0.3 2.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 3.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 2.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 2.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 2.6 GO:0034235 GPI anchor binding(GO:0034235)
0.2 6.3 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.2 2.0 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2 1.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.2 1.5 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 0.6 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.2 0.8 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.2 12.8 GO:0005158 insulin receptor binding(GO:0005158)
0.2 8.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.5 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 0.5 GO:0046848 hydroxyapatite binding(GO:0046848)
0.2 2.9 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 1.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2 3.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 0.5 GO:0070336 flap-structured DNA binding(GO:0070336)
0.2 0.8 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 1.3 GO:0042056 chemoattractant activity(GO:0042056)
0.2 2.1 GO:0004969 histamine receptor activity(GO:0004969)
0.2 4.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.8 GO:0030151 molybdenum ion binding(GO:0030151)
0.2 0.8 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.4 GO:0016768 spermine synthase activity(GO:0016768)
0.1 1.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 2.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 1.7 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 2.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 3.1 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.4 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.2 GO:0043426 MRF binding(GO:0043426)
0.1 1.8 GO:0004630 phospholipase D activity(GO:0004630)
0.1 1.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 1.5 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 3.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 4.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 7.7 GO:0030507 spectrin binding(GO:0030507)
0.1 1.3 GO:0031433 telethonin binding(GO:0031433)
0.1 4.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.8 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 1.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 4.5 GO:0005521 lamin binding(GO:0005521)
0.1 25.6 GO:0008201 heparin binding(GO:0008201)
0.1 1.7 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.1 0.3 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 1.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 2.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 1.5 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.9 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 14.2 GO:0030165 PDZ domain binding(GO:0030165)
0.1 2.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 5.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.7 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 1.6 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 2.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.7 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 7.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.6 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.4 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 5.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 0.5 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 1.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.1 2.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 3.5 GO:0050699 WW domain binding(GO:0050699)
0.0 1.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 2.4 GO:0017046 peptide hormone binding(GO:0017046)
0.0 2.0 GO:0005109 frizzled binding(GO:0005109)
0.0 1.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 7.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.5 GO:0070628 proteasome binding(GO:0070628)
0.0 1.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.3 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271) potassium ion leak channel activity(GO:0022841)
0.0 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.1 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 6.5 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.6 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 2.7 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 1.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 1.7 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.7 GO:0030553 cGMP binding(GO:0030553)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 1.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.2 GO:0071814 lipoprotein particle binding(GO:0071813) protein-lipid complex binding(GO:0071814)
0.0 1.1 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 4.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0042805 actinin binding(GO:0042805)
0.0 3.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.9 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 3.0 GO:0005179 hormone activity(GO:0005179)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014) G-quadruplex DNA binding(GO:0051880)
0.0 0.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0022821 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0 11.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 20.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 2.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.8 GO:0005549 odorant binding(GO:0005549)
0.0 1.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.7 GO:0005254 chloride channel activity(GO:0005254)
0.0 1.6 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 1.0 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 1.4 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 2.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0004556 alpha-amylase activity(GO:0004556)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 32.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 16.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 9.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 8.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 3.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 1.0 PID IL3 PATHWAY IL3-mediated signaling events
0.1 9.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 7.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 4.1 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 1.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 7.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 5.3 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 6.0 PID BMP PATHWAY BMP receptor signaling
0.1 6.4 PID SHP2 PATHWAY SHP2 signaling
0.1 23.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 6.2 PID LKB1 PATHWAY LKB1 signaling events
0.1 4.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 0.8 PID IGF1 PATHWAY IGF1 pathway
0.1 4.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 3.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 4.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 3.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 2.0 PID P73PATHWAY p73 transcription factor network
0.0 1.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 2.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.9 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.8 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 28.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.4 12.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.4 10.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 6.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.3 8.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 8.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 6.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 2.6 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.2 3.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 3.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 6.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 5.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2 3.9 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2 1.2 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.1 4.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 5.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 3.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 8.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.6 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 3.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 1.3 REACTOME OPSINS Genes involved in Opsins
0.1 6.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.0 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 1.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 2.8 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 1.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 4.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.4 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 2.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 2.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 4.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 3.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 2.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 4.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 2.3 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events