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Illumina Body Map 2, young vs old

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Results for JDP2

Z-value: 0.66

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Transcription factors associated with JDP2

Gene Symbol Gene ID Gene Info
ENSG00000140044.8 Jun dimerization protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
JDP2hg19_v2_chr14_+_75894714_75894749-0.202.7e-01Click!

Activity profile of JDP2 motif

Sorted Z-values of JDP2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_97361388 3.78 ENST00000350485.4
ENST00000346867.4
tachykinin, precursor 1
chr20_-_62129163 3.71 ENST00000298049.7
eukaryotic translation elongation factor 1 alpha 2
chr7_+_97361218 3.32 ENST00000319273.5
tachykinin, precursor 1
chr5_-_41794663 3.07 ENST00000510634.1
3-oxoacid CoA transferase 1
chr5_-_41794313 2.68 ENST00000512084.1
3-oxoacid CoA transferase 1
chr10_-_21463116 2.47 ENST00000417816.2
nebulette
chr9_+_34958254 2.43 ENST00000242315.3
KIAA1045
chr2_-_175712479 2.42 ENST00000443238.1
chimerin 1
chr2_-_175711978 2.42 ENST00000409089.2
chimerin 1
chr9_+_34957477 2.42 ENST00000544237.1
KIAA1045
chr2_-_175712270 2.37 ENST00000295497.7
ENST00000444394.1
chimerin 1
chr2_-_220173685 2.32 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
protein tyrosine phosphatase, receptor type, N
chr10_+_88428206 2.31 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LIM domain binding 3
chr16_+_57662138 2.31 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
G protein-coupled receptor 56
chr12_+_7023491 2.22 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr9_-_23826298 2.18 ENST00000380117.1
ELAV like neuron-specific RNA binding protein 2
chr14_-_51562037 2.08 ENST00000338969.5
tripartite motif containing 9
chr12_+_7023735 2.00 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
enolase 2 (gamma, neuronal)
chr6_+_56820018 2.00 ENST00000370746.3
BEN domain containing 6
chr1_-_111148241 1.86 ENST00000440270.1
potassium voltage-gated channel, shaker-related subfamily, member 2
chr14_-_75083313 1.85 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
chr10_+_88428370 1.83 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LIM domain binding 3
chr6_+_56819773 1.77 ENST00000370750.2
BEN domain containing 6
chr19_-_36019123 1.77 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
suprabasin
chr3_+_155860751 1.73 ENST00000471742.1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr7_+_28725585 1.67 ENST00000396298.2
cAMP responsive element binding protein 5
chr10_-_75385711 1.67 ENST00000433394.1
ubiquitin specific peptidase 54
chr8_+_79503458 1.67 ENST00000518467.1
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr16_+_57662419 1.65 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
G protein-coupled receptor 56
chr4_-_176812842 1.58 ENST00000507540.1
glycoprotein M6A
chr13_-_36429763 1.55 ENST00000379893.1
doublecortin-like kinase 1
chrX_-_154493791 1.55 ENST00000369454.3
RAB39B, member RAS oncogene family
chr20_-_17539456 1.50 ENST00000544874.1
ENST00000377868.2
beaded filament structural protein 1, filensin
chr13_-_67802549 1.49 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr8_-_110988070 1.49 ENST00000524391.1
potassium channel, subfamily V, member 1
chr11_-_84028180 1.48 ENST00000280241.8
discs, large homolog 2 (Drosophila)
chr12_-_131200810 1.46 ENST00000536002.1
ENST00000544034.1
RIMS binding protein 2
RP11-662M24.2
chr5_+_176237478 1.44 ENST00000329542.4
unc-5 homolog A (C. elegans)
chr2_-_224467002 1.43 ENST00000421386.1
ENST00000433889.1
secretogranin II
chr10_+_134901388 1.42 ENST00000392607.3
G protein-coupled receptor 123
chr7_-_15014398 1.41 ENST00000437998.1
diacylglycerol kinase, beta 90kDa
chr12_-_71182695 1.38 ENST00000342084.4
protein tyrosine phosphatase, receptor type, R
chr3_-_98241760 1.37 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
claudin domain containing 1
chr9_+_44867571 1.34 ENST00000377548.2
RP11-160N1.10
chr19_+_38880695 1.34 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chr7_-_14942283 1.34 ENST00000402815.1
diacylglycerol kinase, beta 90kDa
chr1_-_166944652 1.31 ENST00000528703.1
ENST00000525740.1
ENST00000529387.1
ENST00000469934.2
ENST00000529071.1
ENST00000526687.1
immunoglobulin-like domain containing receptor 2
chr7_+_147830776 1.29 ENST00000538075.1
contactin associated protein-like 2
chr11_-_133715394 1.29 ENST00000299140.3
ENST00000532889.1
spermatogenesis associated 19
chrX_-_20074895 1.27 ENST00000543767.1
MAP7 domain containing 2
chr4_+_26578293 1.25 ENST00000512840.1
TBC1 domain family, member 19
chr9_-_35112376 1.23 ENST00000488109.2
family with sequence similarity 214, member B
chr3_+_183894566 1.20 ENST00000439647.1
adaptor-related protein complex 2, mu 1 subunit
chr18_+_74207477 1.19 ENST00000532511.1
uncharacterized protein LOC400658
chr2_+_27505260 1.17 ENST00000380075.2
ENST00000296098.4
tripartite motif containing 54
chr6_-_119031228 1.15 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
centrosomal protein 85kDa-like
chr17_-_10701241 1.15 ENST00000578763.1
long intergenic non-protein coding RNA 675
chr14_-_51561784 1.15 ENST00000360392.4
tripartite motif containing 9
chr20_+_4667094 1.14 ENST00000424424.1
ENST00000457586.1
prion protein
chr5_+_169758393 1.13 ENST00000521471.1
ENST00000518357.1
ENST00000436248.3
CTB-114C7.3
chr17_-_70417365 1.13 ENST00000580948.1
long intergenic non-protein coding RNA 511
chr21_+_22519416 1.12 ENST00000535285.1
neural cell adhesion molecule 2
chr3_-_98241713 1.12 ENST00000502288.1
ENST00000512147.1
ENST00000510541.1
ENST00000503621.1
ENST00000511081.1
claudin domain containing 1
chr11_-_84028339 1.10 ENST00000398301.2
discs, large homolog 2 (Drosophila)
chr16_+_89988259 1.10 ENST00000554444.1
ENST00000556565.1
Tubulin beta-3 chain
chr19_-_56056888 1.08 ENST00000592464.1
ENST00000420723.3
SH3 domain binding kinase family, member 3
chr3_-_98241598 1.06 ENST00000513287.1
ENST00000514537.1
ENST00000508071.1
ENST00000507944.1
claudin domain containing 1
chr10_-_116418053 1.06 ENST00000277895.5
actin binding LIM protein 1
chr16_+_57662527 1.05 ENST00000563374.1
ENST00000568234.1
ENST00000565770.1
ENST00000564338.1
ENST00000566164.1
G protein-coupled receptor 56
chr1_-_244006528 1.04 ENST00000336199.5
ENST00000263826.5
v-akt murine thymoma viral oncogene homolog 3
chr4_+_120056939 1.04 ENST00000307128.5
myozenin 2
chr6_+_56819895 1.00 ENST00000370748.3
BEN domain containing 6
chr2_+_166326157 0.98 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
cysteine-serine-rich nuclear protein 3
chr11_-_57417405 0.97 ENST00000524669.1
ENST00000300022.3
yippee-like 4 (Drosophila)
chr6_-_161695042 0.97 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
1-acylglycerol-3-phosphate O-acyltransferase 4
chr4_+_118349545 0.96 ENST00000422145.3
ENST00000437514.1
AC092661.1
chr2_+_208104351 0.96 ENST00000440326.1
AC007879.7
chr16_+_15596123 0.96 ENST00000452191.2
chromosome 16 open reading frame 45
chr6_-_44400720 0.94 ENST00000595057.1
AL133262.1
chr4_+_170581213 0.93 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr3_-_98241358 0.91 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
claudin domain containing 1
chr1_-_166944561 0.91 ENST00000271417.3
immunoglobulin-like domain containing receptor 2
chr11_-_82708519 0.90 ENST00000534301.1
RAB30, member RAS oncogene family
chr10_+_1102303 0.88 ENST00000381329.1
WD repeat domain 37
chr20_+_4666882 0.88 ENST00000379440.4
ENST00000430350.2
prion protein
chr2_-_145275211 0.87 ENST00000462355.1
zinc finger E-box binding homeobox 2
chr19_-_46285646 0.87 ENST00000458663.2
dystrophia myotonica-protein kinase
chr19_+_49467232 0.85 ENST00000599784.1
ENST00000594305.1
CTD-2639E6.9
chr6_-_49755019 0.85 ENST00000304801.3
phosphoglycerate kinase 2
chr7_-_7603957 0.85 ENST00000608807.1
RP5-1159O4.1
chr19_-_35992780 0.83 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
dermokine
chr3_+_183894737 0.83 ENST00000432591.1
ENST00000431779.1
adaptor-related protein complex 2, mu 1 subunit
chr11_+_26495447 0.81 ENST00000531568.1
anoctamin 3
chr2_-_145275228 0.81 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
zinc finger E-box binding homeobox 2
chr10_+_127661942 0.81 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
fibronectin type III and ankyrin repeat domains 1
chr9_-_91793675 0.81 ENST00000375835.4
ENST00000375830.1
SHC (Src homology 2 domain containing) transforming protein 3
chr16_-_14109841 0.81 ENST00000576797.1
ENST00000575424.1
CTD-2135D7.5
chr8_-_141774467 0.80 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr1_+_213224572 0.79 ENST00000543470.1
ENST00000366960.3
ENST00000366959.3
ENST00000543354.1
ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr16_+_57662596 0.78 ENST00000567397.1
ENST00000568979.1
G protein-coupled receptor 56
chr16_+_30077055 0.78 ENST00000564595.2
ENST00000569798.1
aldolase A, fructose-bisphosphate
chr17_+_80317121 0.78 ENST00000333437.4
testis expressed 19
chr9_+_123906331 0.77 ENST00000431571.1
centriolin
chr3_+_138153451 0.77 ENST00000389567.4
ENST00000289135.4
extended synaptotagmin-like protein 3
chr4_+_71588372 0.76 ENST00000536664.1
RUN and FYVE domain containing 3
chr3_-_191000172 0.73 ENST00000427544.2
urotensin 2B
chr2_+_7073174 0.72 ENST00000416587.1
ring finger protein 144A
chr6_-_161695074 0.72 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr9_-_34662651 0.71 ENST00000259631.4
chemokine (C-C motif) ligand 27
chr3_+_69134080 0.70 ENST00000273258.3
ADP-ribosylation-like factor 6 interacting protein 5
chr2_+_87754887 0.69 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
long intergenic non-protein coding RNA 152
chr1_-_108231101 0.69 ENST00000544443.1
ENST00000415432.2
vav 3 guanine nucleotide exchange factor
chr11_+_20620946 0.68 ENST00000525748.1
solute carrier family 6 (neurotransmitter transporter), member 5
chr7_+_102290772 0.67 ENST00000507450.1
speedy/RINGO cell cycle regulator family member E2B
chr17_-_42994283 0.67 ENST00000593179.1
glial fibrillary acidic protein
chr16_+_9449445 0.67 ENST00000564305.1
RP11-243A14.1
chr3_+_98699880 0.66 ENST00000473756.1
long intergenic non-protein coding RNA 973
chr16_+_30077098 0.65 ENST00000395240.3
ENST00000566846.1
aldolase A, fructose-bisphosphate
chr3_-_122512619 0.64 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr2_+_87754989 0.64 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
long intergenic non-protein coding RNA 152
chr7_-_80551671 0.63 ENST00000419255.2
ENST00000544525.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr9_-_124991124 0.63 ENST00000394319.4
ENST00000340587.3
LIM homeobox 6
chr2_-_145275109 0.62 ENST00000431672.2
zinc finger E-box binding homeobox 2
chr1_+_154378049 0.62 ENST00000512471.1
interleukin 6 receptor
chr17_+_79651007 0.62 ENST00000572392.1
ENST00000577012.1
hepatocyte growth factor-regulated tyrosine kinase substrate
chr6_+_72596406 0.61 ENST00000491071.2
regulating synaptic membrane exocytosis 1
chr4_-_36246060 0.61 ENST00000303965.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_+_76311791 0.61 ENST00000586321.1
AC061992.2
chr9_-_123639304 0.60 ENST00000436309.1
PHD finger protein 19
chr12_-_131118370 0.60 ENST00000541840.1
RP11-662M24.2
chr10_+_52152766 0.59 ENST00000596442.1
Uncharacterized protein
chr12_-_10324716 0.59 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr3_-_45957088 0.59 ENST00000539217.1
leucine zipper transcription factor-like 1
chr8_-_123139423 0.58 ENST00000523792.1
RP11-398G24.2
chr11_-_82708435 0.58 ENST00000525117.1
ENST00000532548.1
RAB30, member RAS oncogene family
chr4_+_11627248 0.54 ENST00000510095.1
RP11-281P23.2
chr7_+_127233689 0.53 ENST00000265825.5
ENST00000420086.2
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr3_-_45957534 0.53 ENST00000536047.1
leucine zipper transcription factor-like 1
chr1_-_246580705 0.53 ENST00000541742.1
SET and MYND domain containing 3
chr8_+_70404996 0.53 ENST00000402687.4
ENST00000419716.3
sulfatase 1
chr7_+_102191679 0.52 ENST00000507918.1
ENST00000432940.1
speedy/RINGO cell cycle regulator family member E2
chr3_+_48507210 0.52 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
three prime repair exonuclease 1
chr11_-_57417367 0.52 ENST00000534810.1
yippee-like 4 (Drosophila)
chr17_-_55162360 0.51 ENST00000576871.1
ENST00000576313.1
RP11-166P13.3
chr15_-_43882140 0.51 ENST00000429176.1
diphosphoinositol pentakisphosphate kinase 1
chr3_+_69134124 0.50 ENST00000478935.1
ADP-ribosylation-like factor 6 interacting protein 5
chr1_+_154377669 0.50 ENST00000368485.3
ENST00000344086.4
interleukin 6 receptor
chr2_+_233562015 0.50 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GRB10 interacting GYF protein 2
chr16_+_30953696 0.49 ENST00000566320.2
ENST00000565939.1
F-box and leucine-rich repeat protein 19
chr11_+_44069531 0.49 ENST00000378832.1
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like
chr17_+_75446629 0.49 ENST00000588958.2
ENST00000586128.1
septin 9
chr14_+_86401039 0.49 ENST00000557195.1
CTD-2341M24.1
chr18_-_74839891 0.48 ENST00000581878.1
myelin basic protein
chr5_+_177540444 0.47 ENST00000274605.5
NEDD4 binding protein 3
chr6_+_122720681 0.47 ENST00000368455.4
ENST00000452194.1
heat shock transcription factor 2
chrX_+_1733876 0.46 ENST00000381241.3
acetylserotonin O-methyltransferase
chr6_-_41673552 0.46 ENST00000419574.1
ENST00000445214.1
transcription factor EB
chr8_-_42623747 0.45 ENST00000534622.1
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr1_-_95007193 0.45 ENST00000370207.4
ENST00000334047.7
coagulation factor III (thromboplastin, tissue factor)
chr12_+_48152774 0.45 ENST00000549243.1
solute carrier family 48 (heme transporter), member 1
chr4_+_175839551 0.44 ENST00000404450.4
ENST00000514159.1
ADAM metallopeptidase domain 29
chr12_+_75760714 0.44 ENST00000547144.1
GLI pathogenesis-related 1 like 1
chr3_+_32023232 0.42 ENST00000360311.4
zinc finger protein 860
chr1_-_235116495 0.42 ENST00000549744.1
RP11-443B7.3
chr17_+_66245341 0.42 ENST00000577985.1
archaelysin family metallopeptidase 2
chr22_-_43398442 0.42 ENST00000422336.1
protein kinase C and casein kinase substrate in neurons 2
chr17_-_8263538 0.41 ENST00000535173.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr4_+_175839506 0.41 ENST00000505141.1
ENST00000359240.3
ENST00000445694.1
ADAM metallopeptidase domain 29
chr12_+_10365082 0.41 ENST00000545859.1
GABA(A) receptor-associated protein like 1
chr11_-_66104237 0.40 ENST00000530056.1
Ras and Rab interactor 1
chr19_-_51872233 0.40 ENST00000601435.1
ENST00000291715.1
claudin domain containing 2
chr17_-_73775839 0.39 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3 histone, family 3B (H3.3B)
chr4_+_76481258 0.39 ENST00000311623.4
ENST00000435974.2
chromosome 4 open reading frame 26
chr11_+_28724129 0.39 ENST00000513853.1
RP11-115J23.1
chrX_+_133371077 0.39 ENST00000517294.1
ENST00000370809.4
coiled-coil domain containing 160
chr4_+_22999152 0.38 ENST00000511453.1
RP11-412P11.1
chr11_+_58874701 0.38 ENST00000529618.1
ENST00000534403.1
ENST00000343597.3
family with sequence similarity 111, member B
chr9_-_123638633 0.38 ENST00000456291.1
PHD finger protein 19
chr8_-_42623924 0.38 ENST00000276410.2
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr10_+_121410882 0.37 ENST00000369085.3
BCL2-associated athanogene 3
chr12_+_10365404 0.37 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr2_+_46706725 0.37 ENST00000434431.1
transmembrane protein 247
chr17_+_25799008 0.37 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
kinase suppressor of ras 1
chr12_-_719573 0.37 ENST00000397265.3
ninjurin 2
chr7_-_57207571 0.37 ENST00000331162.4
zinc finger protein 479
chr13_+_53602894 0.36 ENST00000219022.2
olfactomedin 4
chr10_-_4285835 0.36 ENST00000454470.1
long intergenic non-protein coding RNA 702
chr6_-_4347271 0.35 ENST00000437430.2
RP3-527G5.1
chr10_-_4285923 0.35 ENST00000418372.1
ENST00000608792.1
long intergenic non-protein coding RNA 702
chr17_+_79650962 0.35 ENST00000329138.4
hepatocyte growth factor-regulated tyrosine kinase substrate
chr21_-_36421626 0.35 ENST00000300305.3
runt-related transcription factor 1
chr8_-_130253482 0.34 ENST00000509893.2
long intergenic non-protein coding RNA 977
chr11_+_122526383 0.33 ENST00000284273.5
ubiquitin associated and SH3 domain containing B
chr6_-_31745085 0.33 ENST00000375686.3
ENST00000447450.1
von Willebrand factor A domain containing 7
chrX_+_41193407 0.32 ENST00000457138.2
ENST00000441189.2
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr17_+_48712138 0.32 ENST00000515707.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr21_-_36421535 0.32 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
runt-related transcription factor 1
chr20_-_48782639 0.32 ENST00000435301.2
RP11-112L6.3
chr5_+_145583107 0.31 ENST00000506502.1
RNA binding motif protein 27
chr11_+_58874658 0.31 ENST00000411426.1
family with sequence similarity 111, member B

Network of associatons between targets according to the STRING database.

First level regulatory network of JDP2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.1 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.8 3.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.7 5.8 GO:0046952 ketone body catabolic process(GO:0046952)
0.6 2.3 GO:1990502 dense core granule maturation(GO:1990502)
0.4 1.3 GO:0071109 superior temporal gyrus development(GO:0071109)
0.4 2.0 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.4 1.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.3 1.9 GO:0021633 optic nerve structural organization(GO:0021633)
0.3 1.1 GO:0002384 hepatic immune response(GO:0002384)
0.3 2.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 4.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 0.6 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.2 1.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.2 1.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 0.9 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 1.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 7.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 1.0 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 1.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.8 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 4.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.7 GO:0060539 diaphragm development(GO:0060539) negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 5.3 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.2 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.1 0.5 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 3.8 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 1.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.0 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 2.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.2 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.9 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.6 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 2.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 2.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 1.5 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 1.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.3 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 1.0 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.4 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.4 GO:0070836 caveola assembly(GO:0070836)
0.0 0.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 1.2 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.6 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 1.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 1.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 0.4 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.8 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.2 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.7 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 2.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.3 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.4 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 3.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 2.2 GO:1990635 proximal dendrite(GO:1990635)
0.2 1.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 3.1 GO:0033010 paranodal junction(GO:0033010)
0.1 1.2 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.0 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 4.3 GO:0031143 pseudopodium(GO:0031143)
0.1 2.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.0 GO:0036020 endolysosome membrane(GO:0036020)
0.1 0.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 1.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.8 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 3.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.6 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 6.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.8 GO:0071437 invadopodium(GO:0071437)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 1.6 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.8 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.4 3.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 1.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.3 2.0 GO:1903135 cupric ion binding(GO:1903135)
0.3 0.8 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.2 1.0 GO:0051373 FATZ binding(GO:0051373)
0.2 0.7 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 0.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.7 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 6.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 4.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.6 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 3.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 5.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 2.5 GO:0031005 filamin binding(GO:0031005)
0.1 1.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 1.0 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 4.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 2.0 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.5 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 1.7 GO:0070402 NADPH binding(GO:0070402)
0.1 1.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 2.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.8 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 2.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 2.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 1.3 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 2.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 2.9 GO:0000149 SNARE binding(GO:0000149)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID ARF 3PATHWAY Arf1 pathway
0.1 7.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 2.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 5.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 5.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 2.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0 1.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 7.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 4.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 3.7 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism