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Illumina Body Map 2, young vs old

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Results for JUND

Z-value: 1.28

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Transcription factors associated with JUND

Gene Symbol Gene ID Gene Info
JUND
ENSG00000130522.4 JunD proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
JUNDhg19_v2_chr19_-_18391708_183917390.241.9e-01Click!

Activity profile of JUND motif

Sorted Z-values of JUND motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_37545972 5.72 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr1_+_160709029 4.67 ENST00000444090.2
ENST00000441662.2
SLAMF7
SLAM family member 7
chr1_-_153348067 4.58 ENST00000368737.3
S100A12
S100 calcium binding protein A12
chrX_+_78200829 4.54 ENST00000544091.1
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chr5_+_35852797 4.39 ENST00000508941.1
IL7R
interleukin 7 receptor
chr17_-_29645836 4.29 ENST00000578584.1
CTD-2370N5.3
CTD-2370N5.3
chr16_+_31366536 4.13 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr2_+_169926047 3.56 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr1_+_117297007 3.52 ENST00000369478.3
ENST00000369477.1
CD2
CD2 molecule
chr1_+_160709076 3.51 ENST00000359331.4
ENST00000495334.1
SLAMF7
SLAM family member 7
chr1_+_160709055 3.50 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7
SLAM family member 7
chr21_+_42742429 3.38 ENST00000418103.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr6_-_24936170 3.28 ENST00000538035.1
FAM65B
family with sequence similarity 65, member B
chr12_-_68553512 3.27 ENST00000229135.3
IFNG
interferon, gamma
chr3_+_46412345 3.10 ENST00000292303.4
CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
chr10_+_49892904 2.94 ENST00000360890.2
WDFY4
WDFY family member 4
chr14_-_25103472 2.89 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr14_-_25103388 2.75 ENST00000526004.1
ENST00000415355.3
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr16_+_23847339 2.72 ENST00000303531.7
PRKCB
protein kinase C, beta
chr16_+_31366455 2.69 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr15_+_89182178 2.63 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 2.60 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr1_+_26605618 2.53 ENST00000270792.5
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr22_-_36761081 2.43 ENST00000456729.1
ENST00000401701.1
MYH9
myosin, heavy chain 9, non-muscle
chrY_+_15016725 2.42 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr3_-_18466026 2.41 ENST00000417717.2
SATB1
SATB homeobox 1
chr22_+_22749343 2.39 ENST00000390298.2
IGLV7-43
immunoglobulin lambda variable 7-43
chr2_-_231789941 2.36 ENST00000392040.1
ENST00000438398.1
GPR55
G protein-coupled receptor 55
chr15_+_89181974 2.32 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chrX_-_70326455 2.31 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr6_-_41673552 2.28 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr12_+_9142131 2.28 ENST00000356986.3
ENST00000266551.4
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr4_-_84035868 2.23 ENST00000426923.2
ENST00000509973.1
PLAC8
placenta-specific 8
chr18_-_74207146 2.18 ENST00000443185.2
ZNF516
zinc finger protein 516
chr2_-_145275211 2.17 ENST00000462355.1
ZEB2
zinc finger E-box binding homeobox 2
chr6_+_132455526 2.07 ENST00000443303.1
LINC01013
long intergenic non-protein coding RNA 1013
chr12_+_54891495 2.06 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr16_+_85936295 2.03 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
IRF8
interferon regulatory factor 8
chr16_+_28996364 2.02 ENST00000564277.1
LAT
linker for activation of T cells
chr4_-_84035905 2.00 ENST00000311507.4
PLAC8
placenta-specific 8
chr14_+_22978168 1.96 ENST00000390505.1
TRAJ32
T cell receptor alpha joining 32
chr16_+_28996114 1.96 ENST00000395461.3
LAT
linker for activation of T cells
chr7_+_79998864 1.96 ENST00000435819.1
CD36
CD36 molecule (thrombospondin receptor)
chrX_-_154493791 1.94 ENST00000369454.3
RAB39B
RAB39B, member RAS oncogene family
chr17_-_28257080 1.93 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2
slingshot protein phosphatase 2
chr1_+_223889310 1.89 ENST00000434648.1
CAPN2
calpain 2, (m/II) large subunit
chr19_+_35820064 1.80 ENST00000341773.6
ENST00000600131.1
ENST00000270311.6
ENST00000595780.1
ENST00000597916.1
ENST00000593867.1
ENST00000600424.1
ENST00000599811.1
ENST00000536635.2
ENST00000085219.5
ENST00000544992.2
ENST00000419549.2
CD22
CD22 molecule
chr19_-_19739321 1.77 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr13_-_30160925 1.75 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr6_+_63921351 1.73 ENST00000370659.1
FKBP1C
FK506 binding protein 1C
chr1_+_223889285 1.65 ENST00000433674.2
CAPN2
calpain 2, (m/II) large subunit
chr11_+_59856130 1.62 ENST00000278888.3
MS4A2
membrane-spanning 4-domains, subfamily A, member 2
chr1_-_235116495 1.60 ENST00000549744.1
RP11-443B7.3
RP11-443B7.3
chr22_+_23101182 1.57 ENST00000390312.2
IGLV2-14
immunoglobulin lambda variable 2-14
chr12_-_76817036 1.56 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr21_+_42733870 1.55 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr22_+_22707260 1.54 ENST00000390293.1
IGLV5-48
immunoglobulin lambda variable 5-48 (non-functional)
chr12_-_8218926 1.47 ENST00000546241.1
C3AR1
complement component 3a receptor 1
chr21_-_35340759 1.44 ENST00000607953.1
AP000569.9
AP000569.9
chr17_+_65375082 1.43 ENST00000584471.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr11_-_66103867 1.42 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr5_-_141061759 1.37 ENST00000508305.1
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr11_-_66104237 1.37 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr17_-_73150629 1.37 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
HN1
hematological and neurological expressed 1
chr2_+_181988560 1.35 ENST00000424170.1
ENST00000435411.1
AC104820.2
AC104820.2
chr12_-_8218997 1.35 ENST00000307637.4
C3AR1
complement component 3a receptor 1
chr2_-_145275109 1.35 ENST00000431672.2
ZEB2
zinc finger E-box binding homeobox 2
chr4_-_123377880 1.34 ENST00000226730.4
IL2
interleukin 2
chr5_-_140013224 1.32 ENST00000498971.2
CD14
CD14 molecule
chr5_-_140013275 1.32 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr17_-_45899126 1.31 ENST00000007414.3
ENST00000392507.3
OSBPL7
oxysterol binding protein-like 7
chr16_-_67281413 1.30 ENST00000258201.4
FHOD1
formin homology 2 domain containing 1
chr3_-_150996239 1.28 ENST00000309170.3
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr19_-_29026154 1.27 ENST00000593065.1
AC005307.3
AC005307.3
chr17_-_38928414 1.25 ENST00000335552.4
KRT26
keratin 26
chr5_-_141061777 1.25 ENST00000239440.4
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr8_-_135522425 1.25 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr11_-_66103932 1.25 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr21_+_30672433 1.22 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr10_+_17270214 1.22 ENST00000544301.1
VIM
vimentin
chr19_-_54872556 1.22 ENST00000444687.1
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr12_-_95010147 1.19 ENST00000548918.1
TMCC3
transmembrane and coiled-coil domain family 3
chr14_+_73525265 1.19 ENST00000525161.1
RBM25
RNA binding motif protein 25
chr20_+_30946106 1.18 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chr15_+_75335604 1.17 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr6_+_149539767 1.15 ENST00000606202.1
ENST00000536230.1
ENST00000445901.1
TAB2
RP1-111D6.3
TGF-beta activated kinase 1/MAP3K7 binding protein 2
RP1-111D6.3
chr10_-_50396357 1.14 ENST00000453436.1
ENST00000474718.1
C10orf128
chromosome 10 open reading frame 128
chr12_-_95009837 1.12 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr13_-_31038370 1.07 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr1_-_203273676 1.05 ENST00000425698.1
RP11-134P9.1
long intergenic non-protein coding RNA 1136
chr5_-_140013241 1.04 ENST00000519715.1
CD14
CD14 molecule
chr18_-_74839891 1.02 ENST00000581878.1
MBP
myelin basic protein
chr3_-_105588231 1.02 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr12_+_62654119 1.00 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15
ubiquitin specific peptidase 15
chr15_+_67420441 1.00 ENST00000558894.1
SMAD3
SMAD family member 3
chr19_+_35810164 0.99 ENST00000598537.1
CD22
CD22 molecule
chrX_-_153718953 0.98 ENST00000369649.4
ENST00000393586.1
SLC10A3
solute carrier family 10, member 3
chr3_-_69402828 0.95 ENST00000460709.1
FRMD4B
FERM domain containing 4B
chr14_-_23426322 0.93 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chr14_+_22977587 0.93 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr14_-_23426231 0.92 ENST00000556915.1
HAUS4
HAUS augmin-like complex, subunit 4
chr7_-_33080506 0.92 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr5_+_169758393 0.91 ENST00000521471.1
ENST00000518357.1
ENST00000436248.3
CTB-114C7.3
CTB-114C7.3
chr18_+_74207477 0.89 ENST00000532511.1
RP11-17M16.1
uncharacterized protein LOC400658
chr4_-_123542224 0.89 ENST00000264497.3
IL21
interleukin 21
chr17_+_25799008 0.88 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr14_-_23426270 0.87 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4
HAUS augmin-like complex, subunit 4
chr1_-_36020531 0.87 ENST00000440579.1
ENST00000494948.1
KIAA0319L
KIAA0319-like
chr3_+_30647994 0.86 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr11_-_82708435 0.86 ENST00000525117.1
ENST00000532548.1
RAB30
RAB30, member RAS oncogene family
chr17_+_57807062 0.86 ENST00000587259.1
VMP1
vacuole membrane protein 1
chr8_-_74659693 0.85 ENST00000518767.1
STAU2
staufen double-stranded RNA binding protein 2
chr3_-_52713729 0.84 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
PBRM1
polybromo 1
chr10_-_81708854 0.84 ENST00000372292.3
SFTPD
surfactant protein D
chr16_+_29127282 0.81 ENST00000562902.1
RP11-426C22.5
RP11-426C22.5
chr6_+_63921399 0.81 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chr1_-_67266939 0.81 ENST00000304526.2
INSL5
insulin-like 5
chr14_-_23426337 0.81 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4
HAUS augmin-like complex, subunit 4
chr1_+_28527070 0.80 ENST00000596102.1
AL353354.2
AL353354.2
chr15_+_42566384 0.79 ENST00000440615.2
ENST00000318010.8
GANC
glucosidase, alpha; neutral C
chr3_-_155011483 0.79 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr3_-_150996146 0.79 ENST00000494668.1
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr6_+_145118873 0.78 ENST00000432686.1
ENST00000417142.1
UTRN
utrophin
chr22_-_43398442 0.77 ENST00000422336.1
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr4_-_178169927 0.75 ENST00000512516.1
RP11-487E13.1
Uncharacterized protein
chr12_+_62654155 0.75 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15
ubiquitin specific peptidase 15
chr15_-_51535208 0.74 ENST00000405913.3
ENST00000559878.1
CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr5_+_145583107 0.74 ENST00000506502.1
RBM27
RNA binding motif protein 27
chr5_-_60140009 0.73 ENST00000505959.1
ELOVL7
ELOVL fatty acid elongase 7
chr1_+_198189921 0.73 ENST00000391974.3
NEK7
NIMA-related kinase 7
chr2_+_102615416 0.72 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr10_-_31288398 0.70 ENST00000538351.2
ZNF438
zinc finger protein 438
chr10_-_30024716 0.70 ENST00000375398.2
ENST00000375400.3
SVIL
supervillin
chr19_+_11546093 0.68 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr21_+_26934165 0.67 ENST00000456917.1
MIR155HG
MIR155 host gene (non-protein coding)
chr18_-_5419797 0.66 ENST00000542146.1
ENST00000427684.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr3_+_127770455 0.66 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr3_-_49395705 0.63 ENST00000419349.1
GPX1
glutathione peroxidase 1
chr4_-_104119528 0.62 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE
centromere protein E, 312kDa
chr17_-_7590745 0.59 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53
tumor protein p53
chr5_+_145583156 0.57 ENST00000265271.5
RBM27
RNA binding motif protein 27
chr14_-_24711470 0.56 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr12_-_102591604 0.56 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr7_+_100663353 0.54 ENST00000306151.4
MUC17
mucin 17, cell surface associated
chr11_-_6008215 0.54 ENST00000332249.4
OR52L1
olfactory receptor, family 52, subfamily L, member 1
chr4_-_100356551 0.53 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr14_+_58765305 0.53 ENST00000445108.1
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr5_+_147582348 0.51 ENST00000514389.1
SPINK6
serine peptidase inhibitor, Kazal type 6
chr17_+_7590734 0.50 ENST00000457584.2
WRAP53
WD repeat containing, antisense to TP53
chr1_+_41204506 0.50 ENST00000525290.1
ENST00000530965.1
ENST00000416859.2
ENST00000308733.5
NFYC
nuclear transcription factor Y, gamma
chr5_-_60140089 0.49 ENST00000507047.1
ENST00000438340.1
ENST00000425382.1
ENST00000508821.1
ELOVL7
ELOVL fatty acid elongase 7
chr10_-_50396407 0.48 ENST00000374153.2
ENST00000374151.3
C10orf128
chromosome 10 open reading frame 128
chr2_+_75145275 0.47 ENST00000435984.1
AC104135.3
AC104135.3
chr14_+_58765103 0.47 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr15_+_42565464 0.47 ENST00000562170.1
ENST00000562859.1
GANC
glucosidase, alpha; neutral C
chr22_-_39097527 0.47 ENST00000417712.1
JOSD1
Josephin domain containing 1
chr7_-_15014398 0.46 ENST00000437998.1
DGKB
diacylglycerol kinase, beta 90kDa
chr11_-_102826434 0.45 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr3_-_122512619 0.45 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr11_-_82708519 0.45 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr8_+_128426535 0.42 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chr5_-_41794663 0.42 ENST00000510634.1
OXCT1
3-oxoacid CoA transferase 1
chr15_+_42565844 0.41 ENST00000566442.1
GANC
glucosidase, alpha; neutral C
chr12_-_95510743 0.41 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chrX_-_111923145 0.41 ENST00000371968.3
ENST00000536453.1
LHFPL1
lipoma HMGIC fusion partner-like 1
chr17_-_59668550 0.40 ENST00000521764.1
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr9_-_39239171 0.39 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr10_-_50396425 0.39 ENST00000374148.1
C10orf128
chromosome 10 open reading frame 128
chr1_-_6662919 0.39 ENST00000377658.4
ENST00000377663.3
KLHL21
kelch-like family member 21
chr15_-_42565606 0.38 ENST00000307216.6
ENST00000448392.1
TMEM87A
transmembrane protein 87A
chr14_+_73525144 0.37 ENST00000261973.7
ENST00000540173.1
RBM25
RNA binding motif protein 25
chrX_+_22056165 0.37 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr1_-_205053645 0.37 ENST00000367167.3
TMEM81
transmembrane protein 81
chr6_-_44281043 0.36 ENST00000244571.4
AARS2
alanyl-tRNA synthetase 2, mitochondrial
chr1_-_154941350 0.36 ENST00000444179.1
ENST00000414115.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr14_+_73525229 0.36 ENST00000527432.1
ENST00000531500.1
ENST00000525321.1
ENST00000526754.1
RBM25
RNA binding motif protein 25
chr1_-_11918988 0.36 ENST00000376468.3
NPPB
natriuretic peptide B
chr4_-_100356291 0.36 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr7_+_132937820 0.35 ENST00000393161.2
ENST00000253861.4
EXOC4
exocyst complex component 4
chr1_-_205744574 0.33 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1
RAB7, member RAS oncogene family-like 1
chr10_-_74114714 0.33 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
DNAJB12
DnaJ (Hsp40) homolog, subfamily B, member 12
chr12_-_27924209 0.33 ENST00000381273.3
MANSC4
MANSC domain containing 4
chr3_+_130150307 0.32 ENST00000512836.1
COL6A5
collagen, type VI, alpha 5
chr7_-_57207571 0.32 ENST00000331162.4
ZNF479
zinc finger protein 479
chr12_-_8765446 0.31 ENST00000537228.1
ENST00000229335.6
AICDA
activation-induced cytidine deaminase
chr5_-_41794313 0.30 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr4_+_95128996 0.30 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr2_+_161993465 0.30 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr10_+_17686193 0.29 ENST00000377500.1
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr11_+_59522837 0.29 ENST00000437946.2
STX3
syntaxin 3
chr1_-_153935738 0.29 ENST00000417348.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr1_-_153513170 0.28 ENST00000368717.2
S100A5
S100 calcium binding protein A5
chr17_+_1936687 0.28 ENST00000570477.1
DPH1
diphthamide biosynthesis 1
chr10_-_75008620 0.27 ENST00000372950.4
DNAJC9
DnaJ (Hsp40) homolog, subfamily C, member 9
chr1_-_153521597 0.27 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr2_+_36923830 0.27 ENST00000379242.3
ENST00000389975.3
VIT
vitrin
chr4_-_68829226 0.27 ENST00000396188.2
TMPRSS11A
transmembrane protease, serine 11A
chr3_+_191046810 0.26 ENST00000392455.3
ENST00000392456.3
CCDC50
coiled-coil domain containing 50
chr7_+_33765593 0.26 ENST00000311067.3
RP11-89N17.1
HCG1643653; Uncharacterized protein
chr10_+_17686221 0.26 ENST00000540523.1
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1

Network of associatons between targets according to the STRING database.

First level regulatory network of JUND

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.1 3.3 GO:2000309 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309)
0.7 5.7 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.7 5.6 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.7 2.7 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.5 3.7 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.5 2.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.5 2.4 GO:0032796 uropod organization(GO:0032796)
0.4 1.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.4 3.5 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.4 1.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.4 4.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.4 1.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.4 3.5 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.3 3.1 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.3 3.6 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3 0.6 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.3 4.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.3 0.9 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.3 1.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.2 1.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 6.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 4.9 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.2 0.9 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 0.6 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.2 1.7 GO:1903826 arginine transmembrane transport(GO:1903826)
0.2 1.7 GO:0000023 maltose metabolic process(GO:0000023)
0.2 0.7 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.2 4.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 0.7 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2 2.0 GO:0071724 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.2 1.0 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2 2.4 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.2 0.5 GO:0032203 telomere formation via telomerase(GO:0032203)
0.2 0.8 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2 1.0 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 3.5 GO:0016540 protein autoprocessing(GO:0016540)
0.2 2.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 2.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 1.0 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 12.6 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.1 2.0 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.1 1.6 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.7 GO:0039019 pronephric nephron development(GO:0039019)
0.1 1.3 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 1.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 1.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 4.6 GO:0050832 defense response to fungus(GO:0050832)
0.1 0.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.6 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 1.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.8 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.6 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.8 GO:0070836 caveola assembly(GO:0070836)
0.1 6.8 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 1.3 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.6 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.1 0.4 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 1.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 4.0 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell mediated immunity(GO:0002448) mast cell degranulation(GO:0043303)
0.1 1.0 GO:0032526 response to retinoic acid(GO:0032526)
0.1 0.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 1.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.8 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 2.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 2.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.7 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 1.9 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 2.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.3 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 2.3 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 2.3 GO:0006968 cellular defense response(GO:0006968)
0.0 1.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.4 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 6.5 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 3.5 GO:0051225 spindle assembly(GO:0051225)
0.0 0.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 1.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.9 GO:0007566 embryo implantation(GO:0007566)
0.0 0.9 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.0 0.3 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.4 3.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 2.4 GO:0097513 myosin II filament(GO:0097513)
0.3 3.5 GO:0070652 HAUS complex(GO:0070652)
0.2 4.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 9.6 GO:0001772 immunological synapse(GO:0001772)
0.1 2.1 GO:0031209 SCAR complex(GO:0031209)
0.1 6.8 GO:0008305 integrin complex(GO:0008305)
0.1 0.6 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 8.1 GO:0015030 Cajal body(GO:0015030)
0.1 1.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.6 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.0 GO:0033269 internode region of axon(GO:0033269)
0.1 0.4 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.6 GO:0097413 Lewy body(GO:0097413)
0.1 1.3 GO:0032059 bleb(GO:0032059)
0.1 3.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 2.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.8 GO:0070938 contractile ring(GO:0070938)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.7 GO:0036449 microtubule minus-end(GO:0036449)
0.0 14.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 2.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 4.9 GO:0005643 nuclear pore(GO:0005643)
0.0 4.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.7 GO:0033270 paranode region of axon(GO:0033270)
0.0 2.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 5.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.8 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 2.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.2 GO:0070821 tertiary granule membrane(GO:0070821)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0008859 exoribonuclease II activity(GO:0008859)
2.2 4.4 GO:0004917 interleukin-7 receptor activity(GO:0004917)
1.1 5.7 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.7 2.7 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.5 3.7 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.4 2.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.3 4.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3 2.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 1.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 5.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 6.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 0.9 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.2 2.8 GO:0004875 complement receptor activity(GO:0004875)
0.2 1.7 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.2 0.9 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 3.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 0.7 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 2.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 1.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 1.2 GO:1990254 keratin filament binding(GO:1990254)
0.2 1.6 GO:0019863 IgE binding(GO:0019863)
0.2 1.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.7 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 1.0 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 1.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 2.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.4 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.1 1.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 2.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.5 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 2.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 2.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 4.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.9 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 4.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 1.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 1.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 10.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0070330 aromatase activity(GO:0070330)
0.0 1.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 2.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 2.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 4.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 4.8 GO:0003924 GTPase activity(GO:0003924)
0.0 3.2 GO:0005125 cytokine activity(GO:0005125)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 6.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 5.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 6.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 4.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 7.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 4.0 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.0 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 4.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.8 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 1.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 3.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 3.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 6.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 3.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 4.8 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.2 6.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 7.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 4.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 14.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 6.0 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 10.3 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 4.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 2.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 2.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 8.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 2.0 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling