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Illumina Body Map 2, young vs old

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Results for KLF1

Z-value: 0.57

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Transcription factors associated with KLF1

Gene Symbol Gene ID Gene Info
ENSG00000105610.4 Kruppel like factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF1hg19_v2_chr19_-_12997995_129980210.154.0e-01Click!

Activity profile of KLF1 motif

Sorted Z-values of KLF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_5248294 9.13 ENST00000335295.4
hemoglobin, beta
chr15_+_43885252 8.87 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
creatine kinase, mitochondrial 1B
chr15_+_43985084 8.17 ENST00000434505.1
ENST00000411750.1
creatine kinase, mitochondrial 1A
chr8_+_80523962 5.87 ENST00000518491.1
stathmin-like 2
chr13_+_53602894 4.68 ENST00000219022.2
olfactomedin 4
chr11_-_62689046 4.27 ENST00000306960.3
ENST00000543973.1
cholinergic receptor, muscarinic 1
chr20_-_52687059 4.21 ENST00000371435.2
ENST00000395961.3
breast carcinoma amplified sequence 1
chr5_-_83680603 4.20 ENST00000296591.5
EGF-like repeats and discoidin I-like domains 3
chr19_+_35607166 4.17 ENST00000604255.1
ENST00000346446.5
ENST00000344013.6
ENST00000603449.1
ENST00000406988.1
ENST00000605550.1
ENST00000604804.1
ENST00000605552.1
FXYD domain containing ion transport regulator 3
chr7_-_80548493 4.12 ENST00000536800.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr19_+_35606777 4.04 ENST00000604404.1
ENST00000435734.2
ENST00000603181.1
FXYD domain containing ion transport regulator 3
chr8_-_75233563 3.85 ENST00000342232.4
junctophilin 1
chr11_+_1074870 3.70 ENST00000441003.2
ENST00000359061.5
mucin 2, oligomeric mucus/gel-forming
chr17_+_38171681 3.53 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
colony stimulating factor 3 (granulocyte)
chr12_+_57943781 3.47 ENST00000455537.2
ENST00000286452.5
kinesin family member 5A
chr8_-_27115903 3.41 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
stathmin-like 4
chr8_-_143867946 3.40 ENST00000301263.4
lymphocyte antigen 6 complex, locus D
chr1_+_27189631 3.20 ENST00000339276.4
stratifin
chr1_+_47264711 3.19 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
cytochrome P450, family 4, subfamily B, polypeptide 1
chr19_+_35606692 3.19 ENST00000406242.3
ENST00000454903.2
FXYD domain containing ion transport regulator 3
chr7_-_80548667 3.16 ENST00000265361.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr4_-_90756769 3.15 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chr17_+_38171614 3.08 ENST00000583218.1
ENST00000394149.3
colony stimulating factor 3 (granulocyte)
chr8_-_27115931 3.07 ENST00000523048.1
stathmin-like 4
chr2_-_220174166 3.06 ENST00000409251.3
ENST00000451506.1
ENST00000295718.2
ENST00000446182.1
protein tyrosine phosphatase, receptor type, N
chr9_+_74764340 3.01 ENST00000376986.1
ENST00000358399.3
guanine deaminase
chr17_-_74023474 3.01 ENST00000301607.3
envoplakin
chr2_+_17721937 2.99 ENST00000451533.1
visinin-like 1
chr7_+_22766766 2.87 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
interleukin 6 (interferon, beta 2)
chrX_-_153151586 2.85 ENST00000370060.1
ENST00000370055.1
ENST00000420165.1
L1 cell adhesion molecule
chr1_-_39395165 2.85 ENST00000372985.3
rhomboid, veinlet-like 2 (Drosophila)
chr3_+_238456 2.84 ENST00000427688.1
cell adhesion molecule L1-like
chr12_-_8815404 2.74 ENST00000359478.2
ENST00000396549.2
microfibrillar associated protein 5
chr3_+_181429704 2.73 ENST00000431565.2
ENST00000325404.1
SRY (sex determining region Y)-box 2
chr6_+_30850697 2.72 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
discoidin domain receptor tyrosine kinase 1
chr1_+_6845384 2.69 ENST00000303635.7
calmodulin binding transcription activator 1
chr10_+_105036909 2.68 ENST00000369849.4
internexin neuronal intermediate filament protein, alpha
chr17_+_43972010 2.68 ENST00000334239.8
ENST00000446361.3
microtubule-associated protein tau
chr12_+_56477093 2.68 ENST00000549672.1
ENST00000415288.2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr5_-_142077569 2.63 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
fibroblast growth factor 1 (acidic)
chr12_-_85306562 2.62 ENST00000551612.1
ENST00000450363.3
ENST00000552192.1
solute carrier family 6 (neutral amino acid transporter), member 15
chr11_+_394196 2.56 ENST00000331563.2
ENST00000531857.1
plakophilin 3
chr6_+_74405501 2.50 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr20_+_17207636 2.50 ENST00000262545.2
proprotein convertase subtilisin/kexin type 2
chr6_-_3227877 2.49 ENST00000259818.7
tubulin, beta 2B class IIb
chr14_+_42077552 2.46 ENST00000554120.1
leucine rich repeat and fibronectin type III domain containing 5
chr17_-_74023291 2.45 ENST00000586740.1
envoplakin
chr6_+_30850862 2.44 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
discoidin domain receptor tyrosine kinase 1
chr20_-_52687030 2.38 ENST00000411563.1
breast carcinoma amplified sequence 1
chr15_-_76005170 2.36 ENST00000308508.5
chondroitin sulfate proteoglycan 4
chr8_-_21988558 2.34 ENST00000312841.8
hair growth associated
chr6_+_74405804 2.32 ENST00000287097.5
CD109 molecule
chr17_-_34122596 2.32 ENST00000250144.8
matrix metallopeptidase 28
chr11_+_62475130 2.31 ENST00000294117.5
guanine nucleotide binding protein (G protein), gamma 3
chr12_-_85306594 2.28 ENST00000266682.5
solute carrier family 6 (neutral amino acid transporter), member 15
chr6_+_150464155 2.25 ENST00000361131.4
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr13_-_45010939 2.23 ENST00000261489.2
TSC22 domain family, member 1
chr19_-_42916499 2.21 ENST00000601189.1
ENST00000599211.1
lipase, hormone-sensitive
chr2_+_17721920 2.20 ENST00000295156.4
visinin-like 1
chr3_+_238427 2.20 ENST00000397491.2
cell adhesion molecule L1-like
chr19_+_35630022 2.19 ENST00000589209.1
FXYD domain containing ion transport regulator 1
chr12_-_100378006 2.18 ENST00000547776.2
ENST00000329257.7
ENST00000547010.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr20_+_44035200 2.15 ENST00000372717.1
ENST00000360981.4
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr16_+_56225248 2.12 ENST00000262493.6
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr16_-_31147020 2.11 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
protease, serine, 8
chr6_-_114664180 2.10 ENST00000312719.5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr1_+_18434240 2.10 ENST00000251296.1
immunoglobin superfamily, member 21
chr3_+_8775466 2.07 ENST00000343849.2
ENST00000397368.2
caveolin 3
chr2_-_220173685 2.06 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
protein tyrosine phosphatase, receptor type, N
chr8_+_21911054 2.05 ENST00000519850.1
ENST00000381470.3
dematin actin binding protein
chr6_+_44238203 2.04 ENST00000451188.2
transmembrane protein 151B
chr14_+_23846210 2.04 ENST00000339180.4
ENST00000342473.4
ENST00000397227.3
ENST00000555731.1
CKLF-like MARVEL transmembrane domain containing 5
chr5_+_140501581 2.03 ENST00000194152.1
protocadherin beta 4
chr3_+_115342349 2.02 ENST00000393780.3
growth associated protein 43
chr10_+_71211212 2.01 ENST00000373290.2
tetraspanin 15
chr11_-_75379612 2.00 ENST00000526740.1
microtubule-associated protein 6
chr20_+_17207665 1.99 ENST00000536609.1
proprotein convertase subtilisin/kexin type 2
chr12_-_8815215 1.97 ENST00000544889.1
ENST00000543369.1
microfibrillar associated protein 5
chr5_-_172756506 1.96 ENST00000265087.4
stanniocalcin 2
chr11_+_71903169 1.95 ENST00000393676.3
folate receptor 1 (adult)
chr2_+_219824357 1.91 ENST00000302625.4
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr12_-_57443886 1.90 ENST00000300119.3
myosin IA
chr16_-_67427389 1.89 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
tubulin polymerization-promoting protein family member 3
chr11_-_75380165 1.84 ENST00000304771.3
microtubule-associated protein 6
chr14_+_24540761 1.82 ENST00000559207.1
copine VI (neuronal)
chr7_+_73245193 1.81 ENST00000340958.2
claudin 4
chr16_+_89989687 1.81 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
Tubulin beta-3 chain
chr14_+_23845995 1.79 ENST00000359320.3
CKLF-like MARVEL transmembrane domain containing 5
chr17_-_39661849 1.78 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
keratin 13
chr8_+_21912328 1.78 ENST00000432128.1
ENST00000443491.2
ENST00000517600.1
ENST00000523782.2
dematin actin binding protein
chr2_+_220306745 1.78 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG complex locus
chr12_-_8815477 1.76 ENST00000433590.2
microfibrillar associated protein 5
chr12_-_8815299 1.76 ENST00000535336.1
microfibrillar associated protein 5
chr17_-_39661947 1.74 ENST00000590425.1
keratin 13
chr14_+_21569245 1.73 ENST00000556585.2
transmembrane protein 253
chr12_+_26274917 1.72 ENST00000538142.1
sarcospan
chr3_-_168864315 1.70 ENST00000475754.1
ENST00000484519.1
MDS1 and EVI1 complex locus
chr2_+_172950227 1.69 ENST00000341900.6
distal-less homeobox 1
chr17_-_27949911 1.69 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
coronin 6
chr22_+_38071615 1.68 ENST00000215909.5
lectin, galactoside-binding, soluble, 1
chr17_+_33914424 1.66 ENST00000590432.1
adaptor-related protein complex 2, beta 1 subunit
chr10_-_47173994 1.66 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr16_+_30078811 1.65 ENST00000564688.1
aldolase A, fructose-bisphosphate
chr1_-_117210290 1.64 ENST00000369483.1
ENST00000369486.3
immunoglobulin superfamily, member 3
chr12_-_49581152 1.61 ENST00000550811.1
tubulin, alpha 1a
chr11_-_1606513 1.61 ENST00000382171.2
keratin associated protein 5-1
chr9_+_74764278 1.60 ENST00000238018.4
ENST00000376989.3
guanine deaminase
chr3_-_124560257 1.59 ENST00000496703.1
integrin, beta 5
chr8_-_42065187 1.58 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
plasminogen activator, tissue
chr1_-_31712401 1.58 ENST00000373736.2
Na+/K+ transporting ATPase interacting 1
chr3_-_168864427 1.58 ENST00000468789.1
MDS1 and EVI1 complex locus
chr5_+_102595119 1.58 ENST00000510890.1
chromosome 5 open reading frame 30
chr16_+_66400533 1.57 ENST00000341529.3
cadherin 5, type 2 (vascular endothelium)
chr12_-_100378392 1.57 ENST00000549866.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr5_+_71403061 1.57 ENST00000512974.1
ENST00000296755.7
microtubule-associated protein 1B
chr1_+_35225339 1.55 ENST00000339480.1
gap junction protein, beta 4, 30.3kDa
chr2_-_51259641 1.55 ENST00000406316.2
ENST00000405581.1
neurexin 1
chr9_+_112887772 1.53 ENST00000259318.7
A kinase (PRKA) anchor protein 2
chr10_+_31610064 1.53 ENST00000446923.2
ENST00000559476.1
zinc finger E-box binding homeobox 1
chr22_-_44258280 1.52 ENST00000540422.1
sulfotransferase family 4A, member 1
chr1_-_27709793 1.51 ENST00000374027.3
ENST00000374025.3
CD164 sialomucin-like 2
chr1_-_145076068 1.51 ENST00000369345.4
phosphodiesterase 4D interacting protein
chr2_-_51259528 1.50 ENST00000404971.1
neurexin 1
chr1_+_11866207 1.47 ENST00000312413.6
ENST00000346436.6
chloride channel, voltage-sensitive 6
chr3_-_195538728 1.46 ENST00000349607.4
ENST00000346145.4
mucin 4, cell surface associated
chr20_+_44034804 1.45 ENST00000357275.2
ENST00000372720.3
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr18_-_5540471 1.45 ENST00000581833.1
ENST00000544123.1
ENST00000342933.3
ENST00000400111.3
ENST00000585142.1
erythrocyte membrane protein band 4.1-like 3
chr17_-_40575535 1.45 ENST00000357037.5
polymerase I and transcript release factor
chr12_-_125398602 1.44 ENST00000541272.1
ENST00000535131.1
ubiquitin C
chr6_-_78173490 1.43 ENST00000369947.2
5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
chr12_+_116997186 1.39 ENST00000306985.4
microtubule-associated protein 1 light chain 3 beta 2
chr21_-_31311818 1.39 ENST00000535441.1
ENST00000309434.7
ENST00000327783.4
ENST00000389124.2
ENST00000389125.3
ENST00000399913.1
glutamate receptor, ionotropic, kainate 1
chr19_-_36523529 1.34 ENST00000593074.1
CAP-GLY domain containing linker protein 3
chr10_+_47746929 1.34 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
annexin A8-like 2
Protein LOC100996760
chr7_-_944631 1.33 ENST00000453175.2
ArfGAP with dual PH domains 1
chr11_-_6440624 1.33 ENST00000311051.3
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr8_-_22089533 1.32 ENST00000321613.3
phytanoyl-CoA 2-hydroxylase interacting protein
chr2_-_172750733 1.32 ENST00000392592.4
ENST00000422440.2
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr3_-_48130314 1.31 ENST00000439356.1
ENST00000395734.3
ENST00000426837.2
microtubule-associated protein 4
chr8_-_22549856 1.28 ENST00000522910.1
early growth response 3
chr13_+_73632897 1.28 ENST00000377687.4
Kruppel-like factor 5 (intestinal)
chr11_-_62313090 1.27 ENST00000528508.1
ENST00000533365.1
AHNAK nucleoprotein
chr8_+_26435359 1.27 ENST00000311151.5
dihydropyrimidinase-like 2
chr7_+_30960915 1.27 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
aquaporin 1 (Colton blood group)
chr5_-_115910091 1.26 ENST00000257414.8
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr3_-_195538760 1.26 ENST00000475231.1
mucin 4, cell surface associated
chr12_-_110939870 1.24 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr1_-_98510843 1.24 ENST00000413670.2
ENST00000538428.1
MIR137 host gene (non-protein coding)
chr5_-_16617162 1.23 ENST00000306320.9
family with sequence similarity 134, member B
chr11_+_1860832 1.22 ENST00000252898.7
troponin I type 2 (skeletal, fast)
chr3_-_149293990 1.22 ENST00000472417.1
WW domain containing transcription regulator 1
chr2_+_28974489 1.22 ENST00000455580.1
protein phosphatase 1, catalytic subunit, beta isozyme
chr11_-_6426635 1.21 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr16_-_29910365 1.21 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
seizure related 6 homolog (mouse)-like 2
chr17_+_39845134 1.20 ENST00000591776.1
ENST00000469257.1
eukaryotic translation initiation factor 1
chr22_-_39639021 1.20 ENST00000455790.1
platelet-derived growth factor beta polypeptide
chr19_+_13135790 1.19 ENST00000358552.3
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_+_209602156 1.19 ENST00000429156.1
ENST00000366437.3
ENST00000603283.1
ENST00000431096.1
MIR205 host gene (non-protein coding)
chr15_+_78556809 1.19 ENST00000343789.3
ENST00000394852.3
DnaJ (Hsp40) homolog, subfamily A, member 4
chr1_-_94147385 1.17 ENST00000260502.6
breast cancer anti-estrogen resistance 3
chr22_+_31477296 1.16 ENST00000426927.1
ENST00000440425.1
ENST00000358743.1
ENST00000347557.2
ENST00000333137.7
smoothelin
chr10_-_104178857 1.16 ENST00000020673.5
pleckstrin and Sec7 domain containing
chr15_-_42386752 1.15 ENST00000290472.3
phospholipase A2, group IVD (cytosolic)
chr17_+_46125685 1.14 ENST00000579889.1
nuclear factor, erythroid 2-like 1
chr7_+_142982023 1.14 ENST00000359333.3
ENST00000409244.1
ENST00000409541.1
ENST00000410004.1
transmembrane protein 139
chr1_-_59249732 1.13 ENST00000371222.2
jun proto-oncogene
chr2_+_45878790 1.13 ENST00000306156.3
protein kinase C, epsilon
chr12_+_48516463 1.12 ENST00000546465.1
phosphofructokinase, muscle
chr2_-_26205340 1.12 ENST00000264712.3
kinesin family member 3C
chr15_+_90931450 1.11 ENST00000268182.5
ENST00000560738.1
ENST00000560418.1
IQ motif containing GTPase activating protein 1
chr12_+_7037461 1.11 ENST00000396684.2
atrophin 1
chr19_+_38880695 1.11 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chr19_+_35629702 1.10 ENST00000351325.4
FXYD domain containing ion transport regulator 1
chr1_-_27709816 1.09 ENST00000374030.1
CD164 sialomucin-like 2
chr12_+_48516357 1.09 ENST00000549022.1
ENST00000547587.1
ENST00000312352.7
phosphofructokinase, muscle
chr19_+_13135731 1.09 ENST00000587260.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr8_+_38614754 1.08 ENST00000521642.1
transforming, acidic coiled-coil containing protein 1
chr1_+_11866270 1.08 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
chloride channel, voltage-sensitive 6
chr20_+_44035847 1.06 ENST00000372712.2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr9_-_33264557 1.06 ENST00000473781.1
ENST00000488499.1
BCL2-associated athanogene
chr6_+_73331520 1.06 ENST00000342056.2
ENST00000355194.4
potassium voltage-gated channel, KQT-like subfamily, member 5
chrX_+_47077632 1.06 ENST00000457458.2
cyclin-dependent kinase 16
chr5_-_11903337 1.06 ENST00000502551.1
catenin (cadherin-associated protein), delta 2
chr5_+_169931009 1.05 ENST00000328939.4
ENST00000390656.4
Kv channel interacting protein 1
chr12_+_72667203 1.05 ENST00000547300.1
thyrotropin-releasing hormone degrading enzyme
chr20_-_48099182 1.05 ENST00000371741.4
potassium voltage-gated channel, Shab-related subfamily, member 1
chr17_-_7493390 1.04 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SRY (sex determining region Y)-box 15
chr11_-_71781096 1.04 ENST00000535087.1
ENST00000535838.1
nuclear mitotic apparatus protein 1
chr6_-_131291572 1.03 ENST00000529208.1
erythrocyte membrane protein band 4.1-like 2
chr2_-_219151984 1.03 ENST00000444000.1
ENST00000418569.1
transmembrane BAX inhibitor motif containing 1
chr7_+_86274145 1.03 ENST00000439827.1
ENST00000394720.2
ENST00000421579.1
glutamate receptor, metabotropic 3
chr5_-_87980753 1.02 ENST00000511014.2
long intergenic non-protein coding RNA 461
chr3_+_183770835 1.02 ENST00000318351.1
5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
chr3_-_186080012 1.01 ENST00000544847.1
ENST00000265022.3
diacylglycerol kinase, gamma 90kDa
chr2_+_154728426 1.01 ENST00000392825.3
ENST00000434213.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr17_-_46716647 1.01 ENST00000608940.1
RP11-357H14.17
chr18_-_5540384 1.00 ENST00000584670.1
ENST00000582703.1
ENST00000580179.1
erythrocyte membrane protein band 4.1-like 3
chr2_-_55276320 1.00 ENST00000357376.3
reticulon 4
chr12_+_56498312 1.00 ENST00000552766.1
proliferation-associated 2G4, 38kDa
chr5_+_140480083 1.00 ENST00000231130.2
protocadherin beta 3

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.4 GO:0030185 nitric oxide transport(GO:0030185)
1.5 4.6 GO:0006147 guanine catabolic process(GO:0006147)
1.5 5.9 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
1.3 5.1 GO:1990502 dense core granule maturation(GO:1990502)
1.1 3.4 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.9 4.5 GO:0030070 insulin processing(GO:0030070)
0.9 3.5 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.7 2.9 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.7 7.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.6 1.9 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.6 3.2 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.6 3.1 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.6 1.7 GO:0021893 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.5 3.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.5 4.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.5 4.9 GO:0015820 leucine transport(GO:0015820)
0.5 8.2 GO:0006600 creatine metabolic process(GO:0006600)
0.5 4.7 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.5 3.7 GO:0072675 osteoclast fusion(GO:0072675)
0.4 1.3 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.4 2.7 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.4 2.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.4 6.6 GO:0030223 neutrophil differentiation(GO:0030223)
0.4 0.4 GO:0061196 fungiform papilla development(GO:0061196)
0.4 2.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.4 3.3 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.4 2.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.4 3.8 GO:0070560 protein secretion by platelet(GO:0070560)
0.4 1.1 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.4 2.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.4 3.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.4 3.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.4 2.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.3 1.0 GO:0048627 myoblast development(GO:0048627)
0.3 3.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.3 2.0 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.3 1.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 0.9 GO:0033214 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.3 2.2 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.3 1.2 GO:1905176 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.3 1.4 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.3 1.7 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 1.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.3 1.7 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 1.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.3 2.5 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.3 5.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.3 1.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.3 3.6 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 0.7 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.2 2.7 GO:0001714 endodermal cell fate specification(GO:0001714)
0.2 1.0 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.2 1.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 3.4 GO:0035634 response to stilbenoid(GO:0035634)
0.2 0.9 GO:0060262 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.2 2.3 GO:0002159 desmosome assembly(GO:0002159)
0.2 0.7 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.2 1.8 GO:0021592 fourth ventricle development(GO:0021592)
0.2 2.7 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 1.3 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.2 6.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 0.6 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.2 3.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 0.8 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.2 1.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.2 2.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 1.3 GO:0051012 microtubule sliding(GO:0051012)
0.2 2.6 GO:0035766 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) branch elongation involved in ureteric bud branching(GO:0060681) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.2 1.6 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 8.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.2 1.5 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 1.8 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 0.8 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 1.5 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.2 0.8 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 2.1 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 1.8 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 1.9 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1 2.8 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 2.0 GO:0016198 axon choice point recognition(GO:0016198)
0.1 1.7 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.9 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.1 1.3 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.7 GO:0002934 desmosome organization(GO:0002934)
0.1 2.0 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.1 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.1 2.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 1.6 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.7 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 2.4 GO:1900016 negative regulation of fibroblast migration(GO:0010764) negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.1 1.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.5 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.7 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.9 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 5.0 GO:0035640 exploration behavior(GO:0035640)
0.1 0.6 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.3 GO:1903179 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.1 0.9 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.9 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 3.8 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.1 3.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 3.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.0 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.3 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 1.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.7 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 1.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 4.1 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.1 0.7 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.6 GO:0042048 olfactory behavior(GO:0042048)
0.1 6.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.6 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 5.2 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.1 0.9 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 3.7 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 2.7 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.8 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.4 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 2.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 2.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 1.1 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 1.6 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1 8.7 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.7 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.8 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 1.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 3.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.8 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.8 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 1.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.5 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 3.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 1.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 1.5 GO:0030033 microvillus assembly(GO:0030033)
0.1 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.1 2.0 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.7 GO:0006552 leucine catabolic process(GO:0006552)
0.1 5.2 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 1.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 3.7 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 0.5 GO:0001878 response to yeast(GO:0001878)
0.1 1.4 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.1 3.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 1.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 2.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.7 GO:0015824 proline transport(GO:0015824)
0.1 0.6 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 0.9 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.6 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 1.4 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.3 GO:2000674 regulation of type B pancreatic cell apoptotic process(GO:2000674)
0.1 1.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 1.0 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 1.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 3.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 2.2 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.8 GO:0035878 nail development(GO:0035878)
0.0 0.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 1.7 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 1.2 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.7 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.9 GO:0021794 thalamus development(GO:0021794)
0.0 1.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 1.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 1.0 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 1.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.5 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.0 2.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.6 GO:0015671 oxygen transport(GO:0015671)
0.0 2.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.5 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.2 GO:0030252 growth hormone secretion(GO:0030252)
0.0 1.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 5.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 1.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.7 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 1.0 GO:0021591 ventricular system development(GO:0021591)
0.0 1.3 GO:0030516 regulation of axon extension(GO:0030516)
0.0 0.4 GO:1900271 regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 1.0 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.5 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 1.9 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.3 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 2.0 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 1.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.3 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 1.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.9 GO:0006260 DNA replication(GO:0006260)
0.0 1.0 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.5 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.9 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.8 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.0 GO:0060988 lipid tube assembly(GO:0060988)
0.0 2.9 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 1.3 GO:0021987 cerebral cortex development(GO:0021987)
0.0 1.1 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.4 GO:0014047 glutamate secretion(GO:0014047)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.2 3.7 GO:0070702 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.6 2.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4 1.3 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.4 1.6 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.4 2.7 GO:0045298 tubulin complex(GO:0045298)
0.4 1.5 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.3 3.4 GO:1990812 growth cone filopodium(GO:1990812)
0.3 1.6 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.3 8.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.3 1.8 GO:0097513 myosin II filament(GO:0097513)
0.3 3.8 GO:0030314 junctional membrane complex(GO:0030314)
0.3 3.5 GO:0035253 ciliary rootlet(GO:0035253)
0.3 1.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 2.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 4.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 0.9 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.2 0.8 GO:1902912 pyruvate kinase complex(GO:1902912)
0.2 0.8 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.2 2.0 GO:0032584 growth cone membrane(GO:0032584)
0.2 7.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 2.7 GO:0005883 neurofilament(GO:0005883)
0.2 0.8 GO:0071942 XPC complex(GO:0071942)
0.1 6.9 GO:0030057 desmosome(GO:0030057)
0.1 2.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.9 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 14.6 GO:0034707 chloride channel complex(GO:0034707)
0.1 2.2 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.8 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 3.0 GO:0005861 troponin complex(GO:0005861)
0.1 1.1 GO:0035976 AP1 complex(GO:0035976)
0.1 3.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 3.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.7 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 1.5 GO:0005642 annulate lamellae(GO:0005642)
0.1 4.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 4.0 GO:0044295 axonal growth cone(GO:0044295)
0.1 8.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 2.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 10.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.5 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.8 GO:0016342 catenin complex(GO:0016342)
0.1 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 2.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 1.3 GO:0008091 spectrin(GO:0008091)
0.1 3.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.3 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 1.6 GO:0005922 connexon complex(GO:0005922)
0.1 2.7 GO:0035869 ciliary transition zone(GO:0035869)
0.1 11.6 GO:0043204 perikaryon(GO:0043204)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 1.0 GO:0097227 sperm annulus(GO:0097227)
0.1 1.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 4.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.8 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.6 GO:0005833 hemoglobin complex(GO:0005833)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0032021 NELF complex(GO:0032021)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 3.3 GO:0015030 Cajal body(GO:0015030)
0.0 7.7 GO:0030426 growth cone(GO:0030426)
0.0 2.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 4.3 GO:0043679 axon terminus(GO:0043679)
0.0 1.2 GO:0043034 costamere(GO:0043034)
0.0 1.0 GO:0046930 pore complex(GO:0046930)
0.0 4.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 4.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 2.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 3.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 4.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 5.1 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.9 GO:0005811 lipid particle(GO:0005811)
0.0 2.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 8.0 GO:0005874 microtubule(GO:0005874)
0.0 3.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 7.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.7 GO:0031526 brush border membrane(GO:0031526)
0.0 1.1 GO:0005844 polysome(GO:0005844)
0.0 2.0 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 1.7 GO:0034399 nuclear periphery(GO:0034399)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0005298 proline:sodium symporter activity(GO:0005298)
1.5 4.6 GO:0008892 guanine deaminase activity(GO:0008892)
1.5 9.1 GO:0030492 hemoglobin binding(GO:0030492)
0.8 8.0 GO:0004111 creatine kinase activity(GO:0004111)
0.8 3.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.7 2.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.7 2.7 GO:0099609 microtubule lateral binding(GO:0099609)
0.6 3.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.6 1.9 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.6 1.7 GO:0030395 lactose binding(GO:0030395)
0.5 4.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.5 2.6 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.5 2.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.5 1.9 GO:0061714 folic acid receptor activity(GO:0061714)
0.5 2.7 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.4 1.3 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.4 1.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.4 1.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.4 3.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.4 8.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 5.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 5.4 GO:0019215 intermediate filament binding(GO:0019215)
0.3 3.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 2.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 1.7 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.3 1.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 3.5 GO:0038132 neuregulin binding(GO:0038132)
0.2 2.1 GO:0050656 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.2 19.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 1.3 GO:0097001 ceramide binding(GO:0097001)
0.2 2.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 3.0 GO:0031014 troponin T binding(GO:0031014)
0.2 1.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 3.4 GO:0048156 tau protein binding(GO:0048156)
0.2 0.6 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.2 2.4 GO:0015288 porin activity(GO:0015288)
0.2 2.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 3.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 3.6 GO:0045499 chemorepellent activity(GO:0045499)
0.2 1.0 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.2 4.5 GO:0044548 S100 protein binding(GO:0044548)
0.2 1.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 0.8 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.2 2.1 GO:0042731 PH domain binding(GO:0042731)
0.2 1.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 1.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 2.1 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 8.2 GO:0030507 spectrin binding(GO:0030507)
0.1 0.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.8 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 3.2 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 1.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.7 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 1.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.9 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 1.4 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 1.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 1.5 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 2.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.7 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.7 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 3.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 3.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 2.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.6 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.4 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 2.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.9 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.6 GO:0017166 vinculin binding(GO:0017166)
0.1 0.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 2.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.5 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.9 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.9 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 6.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 2.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 7.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.8 GO:0035497 cAMP response element binding(GO:0035497)
0.1 11.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 1.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.3 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 2.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 3.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 2.0 GO:0005123 death receptor binding(GO:0005123)
0.0 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 3.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 1.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 6.5 GO:0002020 protease binding(GO:0002020)
0.0 5.3 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 0.9 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.8 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 3.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 14.5 GO:0015631 tubulin binding(GO:0015631)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 4.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 2.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 2.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.3 GO:0002039 p53 binding(GO:0002039)
0.0 2.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0005272 sodium channel activity(GO:0005272)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.0 1.4 GO:0003774 motor activity(GO:0003774)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.5 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.2 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 4.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.7 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 1.9 ST STAT3 PATHWAY STAT3 Pathway
0.1 24.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 5.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 3.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 7.5 PID NOTCH PATHWAY Notch signaling pathway
0.1 4.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 5.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 3.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 3.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.6 PID FGF PATHWAY FGF signaling pathway
0.0 2.0 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID SHP2 PATHWAY SHP2 signaling
0.0 1.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 3.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 3.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 6.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID P73PATHWAY p73 transcription factor network
0.0 1.2 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 5.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 5.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 2.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 5.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 6.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 5.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 5.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 4.9 REACTOME KINESINS Genes involved in Kinesins
0.1 6.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 3.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 4.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 3.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 2.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 2.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 18.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 4.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 2.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 8.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 3.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 2.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 4.8 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.7 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 2.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 2.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.0 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs