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Illumina Body Map 2, young vs old

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Results for KLF12

Z-value: 0.09

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Transcription factors associated with KLF12

Gene Symbol Gene ID Gene Info
ENSG00000118922.12 Kruppel like factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF12hg19_v2_chr13_-_74708372_74708409-0.193.0e-01Click!

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_54379569 2.18 ENST00000513209.1
RP11-834C11.12
chr7_-_27224842 1.85 ENST00000517402.1
homeobox A11
chr7_-_27224795 1.82 ENST00000006015.3
homeobox A11
chr1_+_153750622 1.65 ENST00000532853.1
solute carrier family 27 (fatty acid transporter), member 3
chr11_-_102401469 1.48 ENST00000260227.4
matrix metallopeptidase 7 (matrilysin, uterine)
chr11_-_57089671 1.36 ENST00000532437.1
tankyrase 1 binding protein 1, 182kDa
chr1_-_201081579 1.36 ENST00000367338.3
ENST00000362061.3
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr12_-_56120838 1.34 ENST00000548160.1
CD63 molecule
chr1_+_24118452 1.33 ENST00000421070.1
lysophospholipase II
chr16_+_28889801 1.31 ENST00000395503.4
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr16_+_28889703 1.31 ENST00000357084.3
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr1_-_43205811 1.25 ENST00000372539.3
ENST00000296387.1
ENST00000539749.1
claudin 19
chr5_+_131705597 1.22 ENST00000435065.2
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr17_+_1665253 1.22 ENST00000254722.4
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_-_23395623 1.21 ENST00000556043.1
protein arginine methyltransferase 5
chr11_-_57089774 1.21 ENST00000527207.1
tankyrase 1 binding protein 1, 182kDa
chr10_-_75401500 1.21 ENST00000359322.4
myozenin 1
chr5_+_131705438 1.21 ENST00000245407.3
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr4_-_111558135 1.21 ENST00000394598.2
ENST00000394595.3
paired-like homeodomain 2
chr7_+_143013198 1.17 ENST00000343257.2
chloride channel, voltage-sensitive 1
chr6_-_43021612 1.14 ENST00000535468.1
cullin 7
chr12_+_81101277 1.13 ENST00000228641.3
myogenic factor 6 (herculin)
chr17_-_80797886 1.12 ENST00000572562.1
zinc finger protein 750
chr10_-_52645416 1.10 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
APOBEC1 complementation factor
chr5_-_139930713 1.07 ENST00000602657.1
steroid receptor RNA activator 1
chr17_+_1665306 1.05 ENST00000571360.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr22_-_24110063 1.04 ENST00000520222.1
ENST00000401675.3
coiled-coil-helix-coiled-coil-helix domain containing 10
chr4_-_87770416 1.04 ENST00000273905.6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr15_-_52944231 1.03 ENST00000546305.2
family with sequence similarity 214, member A
chr7_-_135433534 1.03 ENST00000338588.3
family with sequence similarity 180, member A
chr7_+_123295861 1.02 ENST00000458573.2
ENST00000456238.2
leiomodin 2 (cardiac)
chr7_+_66800928 1.02 ENST00000430244.1
RP11-166O4.5
chr17_+_1665345 0.99 ENST00000576406.1
ENST00000571149.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_-_61190754 0.97 ENST00000216513.4
SIX homeobox 4
chrX_+_49028265 0.94 ENST00000376322.3
ENST00000376327.5
proteolipid protein 2 (colonic epithelium-enriched)
chr19_-_3978083 0.94 ENST00000600794.1
eukaryotic translation elongation factor 2
chr2_-_97509749 0.93 ENST00000331001.2
ENST00000318357.4
ankyrin repeat domain 23
chr16_+_85204882 0.92 ENST00000574293.1
CTC-786C10.1
chr1_+_110036699 0.91 ENST00000496961.1
ENST00000533024.1
ENST00000310611.4
ENST00000527072.1
ENST00000420578.2
ENST00000528785.1
cytochrome b561 family, member D1
chr7_-_100491854 0.91 ENST00000426415.1
ENST00000430554.1
ENST00000412389.1
acetylcholinesterase (Yt blood group)
chr12_-_56120865 0.91 ENST00000548898.1
ENST00000552067.1
CD63 molecule
chr16_+_89168753 0.90 ENST00000544543.1
acyl-CoA synthetase family member 3
chr6_+_31895467 0.89 ENST00000556679.1
ENST00000456570.1
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr2_-_97509729 0.89 ENST00000418232.1
ankyrin repeat domain 23
chr1_-_19229014 0.89 ENST00000538839.1
ENST00000290597.5
aldehyde dehydrogenase 4 family, member A1
chr10_-_91403625 0.87 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
pantothenate kinase 1
chr4_-_100575781 0.85 ENST00000511828.1
Protein LOC285556
chr6_+_133562472 0.85 ENST00000430974.2
ENST00000367895.5
ENST00000355167.3
ENST00000355286.6
eyes absent homolog 4 (Drosophila)
chr3_+_148508845 0.84 ENST00000491148.1
carboxypeptidase B1 (tissue)
chr3_-_49722523 0.84 ENST00000448220.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr1_+_110036674 0.82 ENST00000393709.3
cytochrome b561 family, member D1
chr9_-_34637806 0.82 ENST00000477726.1
sigma non-opioid intracellular receptor 1
chr1_-_31661000 0.82 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
Na+/K+ transporting ATPase interacting 1
chr9_-_131085021 0.82 ENST00000372890.4
TruB pseudouridine (psi) synthase family member 2
chr10_+_23983671 0.82 ENST00000376462.1
KIAA1217
chr6_+_133562744 0.82 ENST00000525849.1
eyes absent homolog 4 (Drosophila)
chr1_-_114355083 0.82 ENST00000261441.5
round spermatid basic protein 1
chr22_-_30198075 0.81 ENST00000411532.1
activating signal cointegrator 1 complex subunit 2
chrX_+_153046456 0.81 ENST00000393786.3
ENST00000370104.1
ENST00000370108.3
ENST00000370101.3
ENST00000430541.1
ENST00000370100.1
SRSF protein kinase 3
chr3_+_154797428 0.80 ENST00000460393.1
membrane metallo-endopeptidase
chr9_+_131085095 0.80 ENST00000372875.3
coenzyme Q4
chr7_+_140373619 0.79 ENST00000483369.1
aarF domain containing kinase 2
chr6_+_133562704 0.79 ENST00000531901.1
eyes absent homolog 4 (Drosophila)
chr11_+_117070037 0.79 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
transgelin
chr16_-_70729496 0.78 ENST00000567648.1
Vac14 homolog (S. cerevisiae)
chr1_+_110036728 0.78 ENST00000369868.3
ENST00000430195.2
cytochrome b561 family, member D1
chr19_-_2050852 0.77 ENST00000541165.1
ENST00000591601.1
MAP kinase interacting serine/threonine kinase 2
chr11_-_34533257 0.77 ENST00000312319.2
E74-like factor 5 (ets domain transcription factor)
chr11_-_64900791 0.76 ENST00000531018.1
synovial apoptosis inhibitor 1, synoviolin
chr6_-_30640811 0.75 ENST00000376442.3
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr16_-_1843694 0.75 ENST00000569769.1
splA/ryanodine receptor domain and SOCS box containing 3
chr19_+_6740888 0.74 ENST00000596673.1
thyroid hormone receptor interactor 10
chr19_-_5785630 0.74 ENST00000586012.1
ENST00000590343.1
Uncharacterized protein
dihydrouridine synthase 3-like (S. cerevisiae)
chr11_-_66103867 0.73 ENST00000424433.2
Ras and Rab interactor 1
chr15_-_75230368 0.72 ENST00000564811.1
ENST00000562233.1
ENST00000567270.1
ENST00000568783.1
cytochrome c oxidase subunit Va
chr16_+_89168993 0.72 ENST00000538340.1
ENST00000543676.1
acyl-CoA synthetase family member 3
chr17_+_7210921 0.71 ENST00000573542.1
eukaryotic translation initiation factor 5A
chr5_-_139422654 0.70 ENST00000289409.4
ENST00000358522.3
ENST00000378238.4
ENST00000289422.7
ENST00000361474.1
ENST00000545385.1
ENST00000394770.1
ENST00000541337.1
neuregulin 2
chrX_+_41583408 0.70 ENST00000302548.4
G protein-coupled receptor 82
chr1_+_214161272 0.70 ENST00000498508.2
ENST00000366958.4
prospero homeobox 1
chr2_-_225266743 0.69 ENST00000409685.3
family with sequence similarity 124B
chr7_-_27702455 0.68 ENST00000265395.2
3-hydroxyisobutyrate dehydrogenase
chrX_-_129299847 0.68 ENST00000319908.3
ENST00000287295.3
apoptosis-inducing factor, mitochondrion-associated, 1
chr1_+_61330931 0.68 ENST00000371191.1
nuclear factor I/A
chr6_+_31895480 0.67 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr2_-_220435963 0.66 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
obscurin-like 1
chr9_-_34637718 0.66 ENST00000378892.1
ENST00000277010.4
sigma non-opioid intracellular receptor 1
chr9_+_137533615 0.66 ENST00000371817.3
collagen, type V, alpha 1
chrX_-_129299638 0.66 ENST00000535724.1
ENST00000346424.2
apoptosis-inducing factor, mitochondrion-associated, 1
chr9_-_34590121 0.66 ENST00000417345.1
ciliary neurotrophic factor receptor
chr17_+_1633755 0.66 ENST00000545662.1
WD repeat domain 81
chr3_-_119379427 0.66 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
popeye domain containing 2
chr17_+_7211280 0.66 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
eukaryotic translation initiation factor 5A
chr10_-_52645379 0.65 ENST00000395489.2
APOBEC1 complementation factor
chr1_+_214161854 0.65 ENST00000435016.1
prospero homeobox 1
chr12_+_53848505 0.64 ENST00000552819.1
ENST00000455667.3
poly(rC) binding protein 2
chrX_+_150866779 0.64 ENST00000370353.3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr5_-_179227540 0.64 ENST00000520875.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr16_+_29819096 0.64 ENST00000568411.1
ENST00000563012.1
ENST00000562557.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr2_+_172864490 0.64 ENST00000315796.4
methionyl aminopeptidase type 1D (mitochondrial)
chr19_+_4474846 0.62 ENST00000589486.1
ENST00000592691.1
Hepatoma-derived growth factor-related protein 2
chr3_+_184037466 0.62 ENST00000441154.1
eukaryotic translation initiation factor 4 gamma, 1
chr16_-_67978016 0.62 ENST00000264005.5
lecithin-cholesterol acyltransferase
chr14_+_75894714 0.61 ENST00000559060.1
Jun dimerization protein 2
chr8_+_22022653 0.61 ENST00000354870.5
ENST00000397816.3
ENST00000306349.8
bone morphogenetic protein 1
chr9_-_34589700 0.61 ENST00000351266.4
ciliary neurotrophic factor receptor
chrX_+_47082408 0.60 ENST00000518022.1
ENST00000276052.6
cyclin-dependent kinase 16
chr11_-_2160180 0.60 ENST00000381406.4
insulin-like growth factor 2 (somatomedin A)
chr22_+_31489344 0.60 ENST00000404574.1
smoothelin
chr16_+_85646891 0.60 ENST00000393243.1
Gse1 coiled-coil protein
chr8_+_22022800 0.60 ENST00000397814.3
bone morphogenetic protein 1
chr2_-_225266711 0.60 ENST00000389874.3
family with sequence similarity 124B
chr11_-_64013288 0.59 ENST00000542235.1
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_-_27418537 0.59 ENST00000408971.2
TGFB1-induced anti-apoptotic factor 1
chr12_+_120740119 0.59 ENST00000536460.1
ENST00000202967.4
sirtuin 4
chr4_-_185726906 0.59 ENST00000513317.1
acyl-CoA synthetase long-chain family member 1
chr17_-_7155274 0.59 ENST00000318988.6
ENST00000575783.1
ENST00000573600.1
CTD nuclear envelope phosphatase 1
chr17_+_7210898 0.59 ENST00000572815.1
eukaryotic translation initiation factor 5A
chr12_-_57328187 0.59 ENST00000293502.1
short chain dehydrogenase/reductase family 9C, member 7
chr9_-_34589734 0.58 ENST00000378980.3
ciliary neurotrophic factor receptor
chr16_+_1291240 0.58 ENST00000561736.1
tryptase alpha/beta 1
chr5_-_142077569 0.58 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
fibroblast growth factor 1 (acidic)
chr19_+_50381308 0.57 ENST00000599049.2
TBC1 domain family, member 17
chr5_-_180632293 0.57 ENST00000334421.5
tripartite motif containing 7
chr16_+_69140122 0.57 ENST00000219322.3
hyaluronan synthase 3
chr19_+_13051206 0.57 ENST00000586760.1
calreticulin
chr17_-_4889508 0.57 ENST00000574606.2
calmodulin binding transcription activator 2
chr11_-_63993690 0.57 ENST00000394546.2
ENST00000541278.1
tRNA phosphotransferase 1
chr7_+_43966018 0.57 ENST00000222402.3
ENST00000446008.1
ENST00000394798.4
ubiquitin-conjugating enzyme E2D 4 (putative)
chr19_-_46272462 0.57 ENST00000317578.6
SIX homeobox 5
chr19_+_41094612 0.57 ENST00000595726.1
SH3KBP1 binding protein 1
chr12_+_53848549 0.56 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
poly(rC) binding protein 2
chr17_+_7210852 0.56 ENST00000576930.1
eukaryotic translation initiation factor 5A
chr19_-_46272106 0.56 ENST00000560168.1
SIX homeobox 5
chr3_+_46924829 0.56 ENST00000313049.5
parathyroid hormone 1 receptor
chr3_-_113415441 0.56 ENST00000491165.1
ENST00000316407.4
KIAA2018
chr19_+_10812108 0.56 ENST00000250237.5
ENST00000592254.1
queuine tRNA-ribosyltransferase 1
chr5_+_52776449 0.56 ENST00000396947.3
follistatin
chr1_+_17866290 0.56 ENST00000361221.3
ENST00000452522.1
ENST00000434513.1
Rho guanine nucleotide exchange factor (GEF) 10-like
chr16_+_85646763 0.56 ENST00000411612.1
ENST00000253458.7
Gse1 coiled-coil protein
chr22_+_47016277 0.55 ENST00000406902.1
GRAM domain containing 4
chr6_-_66417107 0.55 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
eyes shut homolog (Drosophila)
chr14_+_63671105 0.55 ENST00000316754.3
ras homolog family member J
chr14_+_74416989 0.55 ENST00000334571.2
ENST00000554920.1
coenzyme Q6 monooxygenase
chr6_-_30640761 0.55 ENST00000415603.1
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr11_-_61129306 0.55 ENST00000544118.1
cytochrome b561 family, member A3
chr3_+_29322803 0.55 ENST00000396583.3
ENST00000383767.2
RNA binding motif, single stranded interacting protein 3
chr1_-_55341551 0.54 ENST00000537443.1
24-dehydrocholesterol reductase
chr19_-_46000251 0.54 ENST00000590526.1
ENST00000344680.4
ENST00000245923.4
reticulon 2
chr19_+_45312347 0.54 ENST00000270233.6
ENST00000591520.1
basal cell adhesion molecule (Lutheran blood group)
chr8_+_37553261 0.54 ENST00000331569.4
zinc finger protein 703
chr17_-_2117600 0.53 ENST00000572369.1
SMG6 nonsense mediated mRNA decay factor
chr9_-_35754253 0.53 ENST00000436428.2
microseminoprotein, prostate associated
chr11_-_62995986 0.53 ENST00000403374.2
solute carrier family 22, member 25
chr1_+_156084461 0.53 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
lamin A/C
chr16_+_29818857 0.53 ENST00000567444.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr12_+_121416489 0.53 ENST00000541395.1
ENST00000544413.1
HNF1 homeobox A
chr6_+_43612750 0.52 ENST00000372165.4
ENST00000372163.4
radial spoke head 9 homolog (Chlamydomonas)
chr5_+_52776228 0.52 ENST00000256759.3
follistatin
chr9_-_127952032 0.52 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
protein phosphatase 6, catalytic subunit
chr12_-_56122220 0.52 ENST00000552692.1
CD63 molecule
chr2_+_128180842 0.51 ENST00000402125.2
protein C (inactivator of coagulation factors Va and VIIIa)
chr6_-_107436473 0.50 ENST00000369042.1
BEN domain containing 3
chr15_-_75230478 0.50 ENST00000322347.6
cytochrome c oxidase subunit Va
chr17_-_40828969 0.50 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr12_+_2912363 0.50 ENST00000544366.1
FK506 binding protein 4, 59kDa
chr9_-_127952187 0.49 ENST00000451402.1
ENST00000415905.1
protein phosphatase 6, catalytic subunit
chr12_-_56122124 0.49 ENST00000552754.1
CD63 molecule
chr17_-_40829026 0.49 ENST00000412503.1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr9_+_131084815 0.49 ENST00000300452.3
ENST00000609948.1
coenzyme Q4
chr17_-_73266616 0.49 ENST00000579194.1
ENST00000581777.1
MIF4G domain containing
chr14_+_75469606 0.49 ENST00000266126.5
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
chr17_+_78518617 0.49 ENST00000537330.1
ENST00000570891.1
regulatory associated protein of MTOR, complex 1
chr5_-_180632147 0.49 ENST00000274773.7
tripartite motif containing 7
chr19_+_16338416 0.48 ENST00000586543.1
adaptor-related protein complex 1, mu 1 subunit
chr19_-_46389359 0.48 ENST00000302165.3
interferon regulatory factor 2 binding protein 1
chr2_-_74779744 0.47 ENST00000409249.1
lysyl oxidase-like 3
chr16_+_29819372 0.47 ENST00000568544.1
ENST00000569978.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr7_+_65552756 0.47 ENST00000450043.1
AC068533.7
chr12_-_56121580 0.47 ENST00000550776.1
CD63 molecule
chr1_-_48227290 0.47 ENST00000594280.1
FLJ00388
chr8_-_107782463 0.47 ENST00000311955.3
actin-binding Rho activating protein
chrX_-_45060135 0.46 ENST00000398000.2
ENST00000377934.4
chromosome X open reading frame 36
chr3_+_193853927 0.46 ENST00000232424.3
hes family bHLH transcription factor 1
chr1_+_159175201 0.46 ENST00000368121.2
Duffy blood group, atypical chemokine receptor
chr1_-_203274387 0.46 ENST00000432511.1
long intergenic non-protein coding RNA 1136
chr17_+_4981535 0.46 ENST00000318833.3
ZFP3 zinc finger protein
chr1_+_32687971 0.46 ENST00000373586.1
eukaryotic translation initiation factor 3, subunit I
chr19_-_41220957 0.46 ENST00000596357.1
ENST00000243583.6
ENST00000600080.1
ENST00000595254.1
ENST00000601967.1
aarF domain containing kinase 4
chr17_-_7154984 0.45 ENST00000574322.1
CTD nuclear envelope phosphatase 1
chr2_+_36923830 0.45 ENST00000379242.3
ENST00000389975.3
vitrin
chr15_-_43865633 0.45 ENST00000437065.1
diphosphoinositol pentakisphosphate kinase 1
chr14_+_63671577 0.45 ENST00000555125.1
ras homolog family member J
chr17_-_3499125 0.44 ENST00000399759.3
transient receptor potential cation channel, subfamily V, member 1
chr16_+_29819446 0.44 ENST00000568282.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr19_+_50380917 0.44 ENST00000535102.2
TBC1 domain family, member 17
chr11_+_66360665 0.44 ENST00000310190.4
copper chaperone for superoxide dismutase
chr1_+_155178481 0.44 ENST00000368376.3
metaxin 1
chrX_-_99986494 0.44 ENST00000372989.1
ENST00000455616.1
ENST00000454200.2
ENST00000276141.6
synaptotagmin-like 4
chr17_+_41005283 0.43 ENST00000592999.1
amine oxidase, copper containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.8 2.4 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.5 1.0 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.5 3.3 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.4 1.3 GO:0061114 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.4 1.6 GO:0090410 malonate catabolic process(GO:0090410)
0.3 2.7 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3 3.7 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.3 1.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2 1.2 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.2 0.9 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.7 GO:0002027 regulation of heart rate(GO:0002027)
0.2 0.6 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.2 2.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 0.6 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.2 0.4 GO:0007493 endodermal cell fate determination(GO:0007493)
0.2 0.6 GO:0035623 renal glucose absorption(GO:0035623)
0.2 1.9 GO:0002084 protein depalmitoylation(GO:0002084)
0.2 1.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.2 1.2 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 1.8 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.2 3.7 GO:0007501 mesodermal cell fate specification(GO:0007501) embryonic skeletal joint morphogenesis(GO:0060272)
0.2 0.5 GO:0042668 inhibition of neuroepithelial cell differentiation(GO:0002085) auditory receptor cell fate determination(GO:0042668) cell-cell signaling involved in cell fate commitment(GO:0045168) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.9 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.4 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.4 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.1 0.6 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 1.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.5 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.8 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.5 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.6 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.6 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.7 GO:0006574 valine catabolic process(GO:0006574)
0.1 1.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.4 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.1 0.8 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.4 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.4 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.1 0.5 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.3 GO:1902598 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.1 0.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.3 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 1.8 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.1 1.4 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 0.6 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 1.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 1.6 GO:0044849 estrous cycle(GO:0044849)
0.1 1.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.5 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 2.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.5 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 1.4 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.9 GO:2000767 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.2 GO:0032946 positive regulation of mononuclear cell proliferation(GO:0032946) positive regulation of T cell proliferation(GO:0042102) positive regulation of lymphocyte proliferation(GO:0050671) positive regulation of leukocyte proliferation(GO:0070665)
0.1 0.4 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 3.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 0.4 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.1 0.3 GO:0018277 protein deamination(GO:0018277)
0.1 0.7 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.8 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.6 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.1 0.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.2 GO:0060061 Spemann organizer formation(GO:0060061)
0.1 0.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.3 GO:0072302 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) regulation of metanephric glomerular mesangial cell proliferation(GO:0072301) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.3 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 1.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.0 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.6 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 1.2 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.3 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.8 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.5 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.1 0.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.8 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.7 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 1.2 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.4 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211) response to oleic acid(GO:0034201)
0.0 1.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.6 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 1.0 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 1.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 1.0 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.2 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.2 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.7 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.4 GO:0019471 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.5 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.4 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.5 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.8 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.6 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.2 GO:0051715 cytolysis in other organism(GO:0051715)
0.0 1.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0003149 membranous septum morphogenesis(GO:0003149)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0032328 alanine transport(GO:0032328)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.6 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0046836 glycolipid transport(GO:0046836)
0.0 1.1 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.8 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.6 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.3 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.9 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 0.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.2 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.3 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.1 GO:0042476 odontogenesis(GO:0042476)
0.0 0.0 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.0 0.5 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.6 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 1.8 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.3 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.2 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.0 0.2 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.3 GO:0035886 vascular smooth muscle cell differentiation(GO:0035886)
0.0 0.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 1.0 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.0 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 0.4 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.2 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.4 1.8 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.3 3.7 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 1.8 GO:1990393 3M complex(GO:1990393)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.2 2.5 GO:0005642 annulate lamellae(GO:0005642)
0.2 1.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 0.8 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 3.3 GO:0043203 axon hillock(GO:0043203)
0.1 1.0 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.5 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 1.0 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 1.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.3 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.4 GO:0002133 polycystin complex(GO:0002133)
0.1 2.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.6 GO:0097361 CIA complex(GO:0097361)
0.1 1.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 2.0 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.2 GO:0034709 methylosome(GO:0034709)
0.1 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.1 0.2 GO:0071745 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.5 GO:0005638 lamin filament(GO:0005638)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.4 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.0 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 3.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0030897 HOPS complex(GO:0030897)
0.0 0.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 2.1 GO:0030118 clathrin coat(GO:0030118)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 1.4 GO:0031430 M band(GO:0031430)
0.0 2.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 1.6 GO:0014704 intercalated disc(GO:0014704)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.3 2.4 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.3 0.9 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.2 2.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 1.2 GO:0051373 FATZ binding(GO:0051373)
0.2 1.8 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.2 0.9 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 0.5 GO:0005055 laminin receptor activity(GO:0005055)
0.2 1.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 0.5 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.2 0.8 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 1.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 1.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 1.3 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.6 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.4 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 1.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.7 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 2.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.4 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.6 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.6 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.4 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 1.5 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.3 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 0.6 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.3 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.4 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.6 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.3 GO:0016730 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 1.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.3 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.2 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 1.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.8 GO:0031432 titin binding(GO:0031432)
0.1 2.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.9 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.4 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 1.6 GO:0001848 complement binding(GO:0001848)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.6 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.6 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 1.7 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 1.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 3.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 1.0 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.7 GO:0071949 FAD binding(GO:0071949)
0.0 3.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.9 GO:0019956 chemokine binding(GO:0019956)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0042805 actinin binding(GO:0042805)
0.0 0.0 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.0 0.0 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.9 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 ST GAQ PATHWAY G alpha q Pathway
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 7.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 3.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 3.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.8 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 2.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 3.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 2.6 REACTOME TRANSLATION Genes involved in Translation
0.0 0.2 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification