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Illumina Body Map 2, young vs old

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Results for KLF15

Z-value: 0.64

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Transcription factors associated with KLF15

Gene Symbol Gene ID Gene Info
KLF15
ENSG00000163884.3 Kruppel like factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF15hg19_v2_chr3_-_126076264_126076305-0.212.5e-01Click!

Activity profile of KLF15 motif

Sorted Z-values of KLF15 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_47407111 2.54 ENST00000371904.4
CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
chr11_-_64410787 2.53 ENST00000301894.2
NRXN2
neurexin 2
chr20_-_22565101 2.37 ENST00000419308.2
FOXA2
forkhead box A2
chr1_-_47407097 2.37 ENST00000457840.2
CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
chr7_+_29519486 2.30 ENST00000409041.4
CHN2
chimerin 2
chr19_-_10047219 2.11 ENST00000264833.4
OLFM2
olfactomedin 2
chr19_+_55795493 2.02 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chrX_+_152907913 2.01 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr14_-_65439132 1.97 ENST00000533601.2
RAB15
RAB15, member RAS oncogene family
chr16_+_23847339 1.90 ENST00000303531.7
PRKCB
protein kinase C, beta
chr7_+_29519662 1.87 ENST00000424025.2
ENST00000439711.2
ENST00000421775.2
CHN2
chimerin 2
chr3_-_27763803 1.85 ENST00000449599.1
EOMES
eomesodermin
chr8_-_60031762 1.84 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr2_-_20425158 1.82 ENST00000381150.1
SDC1
syndecan 1
chr5_+_17217669 1.81 ENST00000322611.3
BASP1
brain abundant, membrane attached signal protein 1
chr4_+_74702214 1.67 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr6_+_31865552 1.64 ENST00000469372.1
ENST00000497706.1
C2
complement component 2
chr7_-_150675372 1.59 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr2_-_20424844 1.58 ENST00000403076.1
ENST00000254351.4
SDC1
syndecan 1
chr4_-_39640513 1.57 ENST00000511809.1
ENST00000505729.1
SMIM14
small integral membrane protein 14
chr19_-_47975106 1.55 ENST00000539381.1
ENST00000594353.1
ENST00000542837.1
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr2_+_20866424 1.52 ENST00000272224.3
GDF7
growth differentiation factor 7
chr9_+_130911723 1.51 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr7_+_100318423 1.47 ENST00000252723.2
EPO
erythropoietin
chr16_+_23847355 1.45 ENST00000498058.1
PRKCB
protein kinase C, beta
chr14_-_65438865 1.43 ENST00000267512.5
RAB15
RAB15, member RAS oncogene family
chr2_-_233792837 1.43 ENST00000373552.4
ENST00000409079.1
NGEF
neuronal guanine nucleotide exchange factor
chr2_-_208030647 1.43 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr18_-_74207146 1.42 ENST00000443185.2
ZNF516
zinc finger protein 516
chr3_-_49726104 1.41 ENST00000383728.3
ENST00000545762.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr16_+_23847267 1.38 ENST00000321728.7
PRKCB
protein kinase C, beta
chr3_-_27764190 1.35 ENST00000537516.1
EOMES
eomesodermin
chr11_+_7273181 1.34 ENST00000318881.6
SYT9
synaptotagmin IX
chr18_+_67068228 1.34 ENST00000382713.5
DOK6
docking protein 6
chr12_+_57522692 1.33 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr5_-_73937244 1.32 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr5_-_111093081 1.32 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr17_+_42634844 1.31 ENST00000315323.3
FZD2
frizzled family receptor 2
chr1_-_40367668 1.28 ENST00000397332.2
ENST00000429311.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr19_-_47975143 1.26 ENST00000597014.1
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr9_+_130911770 1.25 ENST00000372998.1
LCN2
lipocalin 2
chr1_-_156051789 1.23 ENST00000532414.2
MEX3A
mex-3 RNA binding family member A
chr2_-_70780770 1.23 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chr16_+_56225248 1.22 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr20_-_45280066 1.18 ENST00000279027.4
SLC13A3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr20_-_45280091 1.16 ENST00000396360.1
ENST00000435032.1
ENST00000413164.2
ENST00000372121.1
ENST00000339636.3
SLC13A3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr19_+_11457175 1.16 ENST00000458408.1
ENST00000586451.1
ENST00000588592.1
CCDC159
coiled-coil domain containing 159
chr14_+_32546274 1.15 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr15_-_45480147 1.14 ENST00000560734.1
SHF
Src homology 2 domain containing F
chr7_-_92463210 1.14 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr16_+_2521500 1.12 ENST00000293973.1
NTN3
netrin 3
chr19_+_17858509 1.11 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1
FCH domain only 1
chr10_+_83634940 1.10 ENST00000372141.2
ENST00000404547.1
NRG3
neuregulin 3
chr17_-_42276574 1.10 ENST00000589805.1
ATXN7L3
ataxin 7-like 3
chr17_-_13505219 1.09 ENST00000284110.1
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr15_-_45480153 1.09 ENST00000560471.1
ENST00000560540.1
SHF
Src homology 2 domain containing F
chr3_+_11034403 1.09 ENST00000287766.4
ENST00000425938.1
SLC6A1
solute carrier family 6 (neurotransmitter transporter), member 1
chr19_+_11457232 1.09 ENST00000587531.1
CCDC159
coiled-coil domain containing 159
chr14_+_90528109 1.08 ENST00000282146.4
KCNK13
potassium channel, subfamily K, member 13
chr1_-_32801825 1.08 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr19_+_18284477 1.08 ENST00000407280.3
IFI30
interferon, gamma-inducible protein 30
chr12_+_19282643 1.07 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr3_-_49726486 1.06 ENST00000449682.2
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr11_-_102323740 1.05 ENST00000398136.2
TMEM123
transmembrane protein 123
chr19_-_11689803 1.04 ENST00000591319.1
ACP5
acid phosphatase 5, tartrate resistant
chr6_-_29595779 1.04 ENST00000355973.3
ENST00000377012.4
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr1_-_177133818 1.03 ENST00000424564.2
ENST00000361833.2
ASTN1
astrotactin 1
chr15_+_90728145 1.02 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr7_+_65670186 1.02 ENST00000304842.5
ENST00000442120.1
TPST1
tyrosylprotein sulfotransferase 1
chr1_-_205313304 1.01 ENST00000539253.1
ENST00000607826.1
KLHDC8A
kelch domain containing 8A
chr5_+_61602236 1.00 ENST00000514082.1
ENST00000407818.3
KIF2A
kinesin heavy chain member 2A
chr20_+_13976015 0.98 ENST00000217246.4
MACROD2
MACRO domain containing 2
chr2_+_74229812 0.98 ENST00000305799.7
TET3
tet methylcytosine dioxygenase 3
chr12_+_120933904 0.96 ENST00000550178.1
ENST00000550845.1
ENST00000549989.1
ENST00000552870.1
DYNLL1
dynein, light chain, LC8-type 1
chr2_-_165477971 0.96 ENST00000446413.2
GRB14
growth factor receptor-bound protein 14
chr3_-_188665428 0.95 ENST00000444488.1
TPRG1-AS1
TPRG1 antisense RNA 1
chr11_-_46142615 0.95 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr14_-_67982146 0.95 ENST00000557779.1
ENST00000557006.1
TMEM229B
transmembrane protein 229B
chr12_+_120933859 0.94 ENST00000242577.6
ENST00000548214.1
ENST00000392508.2
DYNLL1
dynein, light chain, LC8-type 1
chr4_-_111120334 0.93 ENST00000503885.1
ELOVL6
ELOVL fatty acid elongase 6
chr4_+_74735102 0.92 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr18_+_74207477 0.91 ENST00000532511.1
RP11-17M16.1
uncharacterized protein LOC400658
chr5_+_110559603 0.90 ENST00000512453.1
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr2_-_73511559 0.89 ENST00000521871.1
FBXO41
F-box protein 41
chr5_+_110559784 0.89 ENST00000282356.4
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr3_+_184097905 0.87 ENST00000450923.1
CHRD
chordin
chr11_+_22646739 0.87 ENST00000428556.2
AC103801.2
AC103801.2
chr4_+_39046615 0.87 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr7_+_144052381 0.86 ENST00000498580.1
ENST00000056217.5
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr15_+_57668695 0.85 ENST00000281282.5
CGNL1
cingulin-like 1
chr14_-_67981916 0.85 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr19_-_1863567 0.83 ENST00000250916.4
KLF16
Kruppel-like factor 16
chr2_-_198175495 0.83 ENST00000409153.1
ENST00000409919.1
ENST00000539527.1
ANKRD44
ankyrin repeat domain 44
chr17_+_75369400 0.83 ENST00000590059.1
SEPT9
septin 9
chr19_-_11689752 0.82 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5
acid phosphatase 5, tartrate resistant
chr15_-_38852251 0.82 ENST00000558432.1
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr4_-_39640700 0.81 ENST00000295958.5
SMIM14
small integral membrane protein 14
chr4_-_6474173 0.80 ENST00000382599.4
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr11_-_46142948 0.78 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr1_-_93426998 0.77 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr13_+_98795664 0.77 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr3_-_10547333 0.76 ENST00000383800.4
ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr7_+_2671568 0.76 ENST00000258796.7
TTYH3
tweety family member 3
chr6_-_119670919 0.76 ENST00000368468.3
MAN1A1
mannosidase, alpha, class 1A, member 1
chr18_-_5895954 0.76 ENST00000581347.2
TMEM200C
transmembrane protein 200C
chr3_+_101546827 0.75 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr3_+_184098065 0.74 ENST00000348986.3
CHRD
chordin
chr14_+_92980111 0.73 ENST00000216487.7
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr1_-_241520385 0.72 ENST00000366564.1
RGS7
regulator of G-protein signaling 7
chr3_+_195943369 0.71 ENST00000296327.5
SLC51A
solute carrier family 51, alpha subunit
chr4_+_79697495 0.71 ENST00000502871.1
ENST00000335016.5
BMP2K
BMP2 inducible kinase
chr2_-_61697862 0.70 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr3_+_184097836 0.70 ENST00000204604.1
ENST00000310236.3
CHRD
chordin
chr11_-_72496976 0.70 ENST00000539138.1
ENST00000542989.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr5_-_11904152 0.70 ENST00000304623.8
ENST00000458100.2
CTNND2
catenin (cadherin-associated protein), delta 2
chr22_+_48972118 0.69 ENST00000358295.5
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr11_-_71159458 0.69 ENST00000355527.3
DHCR7
7-dehydrocholesterol reductase
chr5_-_11904100 0.68 ENST00000359640.2
CTNND2
catenin (cadherin-associated protein), delta 2
chr7_-_142120321 0.68 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr4_-_170947446 0.68 ENST00000507601.1
ENST00000512698.1
MFAP3L
microfibrillar-associated protein 3-like
chr7_-_92465868 0.68 ENST00000424848.2
CDK6
cyclin-dependent kinase 6
chr7_-_767249 0.68 ENST00000403562.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr3_-_10547192 0.67 ENST00000360273.2
ENST00000343816.4
ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr22_+_42949925 0.67 ENST00000327678.5
ENST00000340239.4
ENST00000407614.4
ENST00000335879.5
SERHL2
serine hydrolase-like 2
chr15_-_27018175 0.67 ENST00000311550.5
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr3_+_46923670 0.67 ENST00000427125.2
ENST00000430002.2
PTH1R
parathyroid hormone 1 receptor
chr6_+_6588316 0.67 ENST00000379953.2
LY86
lymphocyte antigen 86
chr18_+_13218769 0.67 ENST00000399848.3
ENST00000361205.4
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr10_+_35415851 0.66 ENST00000374726.3
CREM
cAMP responsive element modulator
chr5_-_141257954 0.66 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr9_+_101867387 0.66 ENST00000374990.2
ENST00000552516.1
TGFBR1
transforming growth factor, beta receptor 1
chr9_+_101867359 0.66 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr6_-_143832793 0.65 ENST00000438118.2
FUCA2
fucosidase, alpha-L- 2, plasma
chr10_+_21823079 0.64 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_-_38273840 0.64 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr17_+_30593195 0.64 ENST00000431505.2
ENST00000269051.4
ENST00000538145.1
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr1_-_151689259 0.64 ENST00000420342.1
ENST00000290583.4
CELF3
CUGBP, Elav-like family member 3
chr19_-_42636617 0.64 ENST00000529067.1
ENST00000529952.1
ENST00000533720.1
ENST00000389341.5
ENST00000342301.4
POU2F2
POU class 2 homeobox 2
chr1_+_173837488 0.64 ENST00000427304.1
ENST00000432989.1
ENST00000367702.1
ZBTB37
zinc finger and BTB domain containing 37
chr22_+_22673051 0.64 ENST00000390289.2
IGLV5-52
immunoglobulin lambda variable 5-52
chr6_-_32157947 0.63 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr7_-_105029329 0.63 ENST00000393651.3
ENST00000460391.1
SRPK2
SRSF protein kinase 2
chr7_-_28220354 0.63 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr1_-_241520525 0.63 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chr4_+_174089951 0.62 ENST00000512285.1
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr13_-_52026730 0.62 ENST00000420668.2
INTS6
integrator complex subunit 6
chr11_+_17756279 0.62 ENST00000265969.6
KCNC1
potassium voltage-gated channel, Shaw-related subfamily, member 1
chr11_+_369804 0.62 ENST00000329962.6
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr4_-_170947485 0.62 ENST00000504999.1
MFAP3L
microfibrillar-associated protein 3-like
chr2_+_5832799 0.61 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr2_-_220173685 0.61 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr19_+_589893 0.60 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr13_+_95364963 0.60 ENST00000438290.2
SOX21-AS1
SOX21 antisense RNA 1 (head to head)
chr22_-_43583079 0.60 ENST00000216129.6
TTLL12
tubulin tyrosine ligase-like family, member 12
chr2_+_39893043 0.59 ENST00000281961.2
TMEM178A
transmembrane protein 178A
chr6_-_119670898 0.59 ENST00000368466.2
MAN1A1
mannosidase, alpha, class 1A, member 1
chr21_-_40720995 0.59 ENST00000380749.5
HMGN1
high mobility group nucleosome binding domain 1
chr5_+_61601965 0.59 ENST00000401507.3
KIF2A
kinesin heavy chain member 2A
chr11_-_8954491 0.59 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
C11orf16
chromosome 11 open reading frame 16
chr16_+_81478775 0.58 ENST00000537098.3
CMIP
c-Maf inducing protein
chr7_+_94285637 0.58 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr2_-_9143786 0.58 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr2_+_27371866 0.58 ENST00000296096.5
TCF23
transcription factor 23
chr17_-_42277203 0.57 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr5_+_139027877 0.57 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr15_-_72766533 0.56 ENST00000562573.1
RP11-1007O24.3
RP11-1007O24.3
chr7_+_30323923 0.56 ENST00000323037.4
ZNRF2
zinc and ring finger 2
chr11_-_64612041 0.56 ENST00000342711.5
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr6_-_143832820 0.55 ENST00000002165.6
FUCA2
fucosidase, alpha-L- 2, plasma
chr22_-_50970506 0.55 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr6_+_24495185 0.55 ENST00000348925.2
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr13_-_49107303 0.55 ENST00000344532.3
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr16_-_57513657 0.54 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
DOK4
docking protein 4
chr11_+_45918092 0.54 ENST00000395629.2
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr20_-_48099182 0.53 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr15_-_34875771 0.53 ENST00000267731.7
GOLGA8B
golgin A8 family, member B
chr14_+_32546485 0.53 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5
Rho GTPase activating protein 5
chr7_-_94285511 0.53 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr19_-_11688951 0.53 ENST00000589792.1
ACP5
acid phosphatase 5, tartrate resistant
chr17_+_65821780 0.52 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
BPTF
bromodomain PHD finger transcription factor
chr2_-_9771075 0.51 ENST00000446619.1
ENST00000238081.3
YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
chr2_-_165697920 0.51 ENST00000342193.4
ENST00000375458.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr20_-_62710832 0.51 ENST00000395042.1
RGS19
regulator of G-protein signaling 19
chr16_+_50187556 0.50 ENST00000561678.1
ENST00000357464.3
PAPD5
PAP associated domain containing 5
chr9_-_6015607 0.50 ENST00000259569.5
RANBP6
RAN binding protein 6
chr19_-_47975417 0.50 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr10_+_114709999 0.50 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr3_+_238273 0.50 ENST00000256509.2
CHL1
cell adhesion molecule L1-like
chr12_+_56435637 0.50 ENST00000356464.5
ENST00000552361.1
RPS26
ribosomal protein S26
chr3_+_184279566 0.50 ENST00000330394.2
EPHB3
EPH receptor B3
chr6_+_31683117 0.50 ENST00000375825.3
ENST00000375824.1
LY6G6D
lymphocyte antigen 6 complex, locus G6D
chr16_+_50300427 0.50 ENST00000394697.2
ENST00000566433.2
ENST00000538642.1
ADCY7
adenylate cyclase 7
chr3_-_197282821 0.50 ENST00000445160.2
ENST00000446746.1
ENST00000432819.1
ENST00000392379.1
ENST00000441275.1
ENST00000392378.2
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr1_+_206730484 0.49 ENST00000304534.8
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr11_+_117049854 0.49 ENST00000278951.7
SIDT2
SID1 transmembrane family, member 2
chr5_+_61602055 0.49 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr12_+_123849462 0.49 ENST00000543072.1
hsa-mir-8072
hsa-mir-8072
chr1_+_180199393 0.49 ENST00000263726.2
LHX4
LIM homeobox 4
chr13_-_52027134 0.48 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr15_-_65067773 0.48 ENST00000300069.4
RBPMS2
RNA binding protein with multiple splicing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
1.1 3.4 GO:0048627 myoblast development(GO:0048627)
1.1 3.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.0 4.9 GO:0003095 pressure natriuresis(GO:0003095)
0.8 2.3 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.6 1.8 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.6 2.4 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.6 2.8 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.5 1.6 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.4 2.3 GO:0015744 tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746) succinate transmembrane transport(GO:0071422)
0.4 1.1 GO:0060596 mammary placode formation(GO:0060596)
0.4 1.8 GO:2001076 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.3 1.0 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.3 1.0 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.3 2.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 0.8 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.3 2.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.3 1.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.3 1.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.3 1.3 GO:1905073 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.2 1.5 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 0.9 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 0.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 0.6 GO:0061386 closure of optic fissure(GO:0061386)
0.2 0.4 GO:0003192 mitral valve formation(GO:0003192)
0.2 1.4 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 1.3 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.2 1.3 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 2.2 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.3 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.2 0.7 GO:1990502 dense core granule maturation(GO:1990502)
0.2 0.5 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.2 0.6 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 0.5 GO:0050894 determination of affect(GO:0050894)
0.2 0.5 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.4 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.9 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 3.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.0 GO:0006540 glutamate decarboxylation to succinate(GO:0006540) gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 2.1 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.5 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 2.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.1 1.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.8 GO:0032252 secretory granule localization(GO:0032252)
0.1 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.7 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.3 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 2.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 1.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.4 GO:0060032 notochord regression(GO:0060032)
0.1 2.6 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.2 GO:0035989 tendon development(GO:0035989)
0.1 0.6 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0090101)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.6 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.5 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 1.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.7 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.1 GO:0072054 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.1 0.5 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.4 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.3 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.1 1.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.4 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.6 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 1.2 GO:0033227 dsRNA transport(GO:0033227)
0.1 1.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.9 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.0 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.7 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.2 GO:1900390 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1 0.2 GO:0019085 early viral transcription(GO:0019085)
0.1 0.2 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 0.9 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.5 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.7 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.1 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.1 0.2 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.4 GO:1901490 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) regulation of lymphangiogenesis(GO:1901490)
0.1 0.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.4 GO:0016180 snRNA processing(GO:0016180)
0.1 0.3 GO:0019086 late viral transcription(GO:0019086)
0.1 0.5 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.1 1.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.4 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.1 0.7 GO:0032782 bile acid secretion(GO:0032782)
0.1 1.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.4 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.6 GO:0035864 response to potassium ion(GO:0035864)
0.0 0.2 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 3.7 GO:1903307 positive regulation of regulated secretory pathway(GO:1903307)
0.0 1.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 1.8 GO:0035640 exploration behavior(GO:0035640)
0.0 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.6 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.7 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.7 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 1.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.7 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.5 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.5 GO:0015816 glycine transport(GO:0015816)
0.0 0.8 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.9 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.4 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.2 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 1.8 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.9 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 1.6 GO:0009409 response to cold(GO:0009409)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 1.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.6 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.2 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.7 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 2.1 GO:0090307 mitotic spindle assembly(GO:0090307)
0.0 0.3 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.5 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 1.0 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.5 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.5 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.7 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.6 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151) phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.6 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.5 GO:0048557 embryonic digestive tract morphogenesis(GO:0048557)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.1 GO:1990418 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721) response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.6 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.5 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.0 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.4 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 1.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 0.6 GO:0098855 HCN channel complex(GO:0098855)
0.1 1.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.2 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.1 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.1 GO:0032039 integrator complex(GO:0032039)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.5 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.7 GO:0001940 male pronucleus(GO:0001940)
0.0 0.5 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.9 GO:0000124 SAGA complex(GO:0000124)
0.0 2.1 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 3.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 2.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 4.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 7.0 GO:0043204 perikaryon(GO:0043204)
0.0 3.5 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.9 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.0 GO:0044299 C-fiber(GO:0044299)
0.0 0.5 GO:0070938 contractile ring(GO:0070938)
0.0 4.5 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.5 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 0.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0031105 septin complex(GO:0031105)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.8 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.7 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.3 GO:0030136 clathrin-coated vesicle(GO:0030136)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
1.0 4.9 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.6 1.8 GO:0098770 FBXO family protein binding(GO:0098770)
0.5 1.5 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.4 1.3 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.4 1.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.4 2.3 GO:0017153 citrate transmembrane transporter activity(GO:0015137) succinate transmembrane transporter activity(GO:0015141) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.3 1.0 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.3 0.9 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.2 1.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 2.3 GO:0045545 syndecan binding(GO:0045545)
0.2 0.6 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.2 1.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 1.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 1.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 3.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 0.5 GO:0031877 somatostatin receptor binding(GO:0031877)
0.2 2.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 2.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.3 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 0.7 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.4 GO:0016768 spermine synthase activity(GO:0016768)
0.1 2.4 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.5 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 1.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 1.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.3 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 1.3 GO:0005114 transforming growth factor beta receptor activity, type I(GO:0005025) type II transforming growth factor beta receptor binding(GO:0005114)
0.1 1.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 1.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.4 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1 0.4 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.3 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.1 1.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.6 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.4 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.5 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 0.9 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 2.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 1.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.5 GO:0004985 opioid receptor activity(GO:0004985)
0.0 7.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.8 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 3.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.7 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 2.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 2.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 2.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 1.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 2.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.9 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.0 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 1.1 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 4.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 2.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 2.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 3.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 3.4 PID BMP PATHWAY BMP receptor signaling
0.0 1.4 PID EPO PATHWAY EPO signaling pathway
0.0 1.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 2.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 2.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 4.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 ST ADRENERGIC Adrenergic Pathway
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 4.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 4.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 2.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 0.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 3.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 2.1 REACTOME KINESINS Genes involved in Kinesins
0.0 1.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 3.8 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 2.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.6 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 2.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 2.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 3.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA