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Illumina Body Map 2, young vs old

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Results for KLF3

Z-value: 0.15

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Transcription factors associated with KLF3

Gene Symbol Gene ID Gene Info
KLF3
ENSG00000109787.8 Kruppel like factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF3hg19_v2_chr4_+_38665810_38665827-0.067.4e-01Click!

Activity profile of KLF3 motif

Sorted Z-values of KLF3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_11370330 2.20 ENST00000241808.4
ENST00000435245.2
PRM2
protamine 2
chr20_+_3052264 2.12 ENST00000217386.2
OXT
oxytocin/neurophysin I prepropeptide
chr20_+_2795626 1.96 ENST00000603872.1
ENST00000380589.4
C20orf141
chromosome 20 open reading frame 141
chr4_-_15964830 1.90 ENST00000259989.6
FGFBP2
fibroblast growth factor binding protein 2
chr16_+_1290694 1.88 ENST00000338844.3
TPSAB1
tryptase alpha/beta 1
chr4_-_82136114 1.73 ENST00000395578.1
ENST00000418486.2
PRKG2
protein kinase, cGMP-dependent, type II
chrX_-_152486108 1.62 ENST00000356661.5
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr16_+_1306093 1.61 ENST00000211076.3
TPSD1
tryptase delta 1
chr20_+_2795609 1.60 ENST00000554164.1
ENST00000380593.4
TMEM239
TMEM239
transmembrane protein 239
CDNA FLJ26142 fis, clone TST04526; Transmembrane protein 239; Uncharacterized protein
chrX_+_2670066 1.56 ENST00000381174.5
ENST00000419513.2
ENST00000426774.1
XG
Xg blood group
chrX_+_142113704 1.52 ENST00000446864.1
ENST00000370504.3
SPANXN4
SPANX family, member N4
chr16_+_1290725 1.51 ENST00000461509.2
TPSAB1
tryptase alpha/beta 1
chr17_+_7323634 1.49 ENST00000323675.3
SPEM1
spermatid maturation 1
chr11_-_5248294 1.46 ENST00000335295.4
HBB
hemoglobin, beta
chr12_-_13256571 1.41 ENST00000545401.1
ENST00000432710.2
ENST00000351606.6
GSG1
germ cell associated 1
chr7_+_116165754 1.36 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr15_-_90233907 1.35 ENST00000561224.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr6_-_35109080 1.34 ENST00000486638.1
ENST00000505400.1
ENST00000412155.2
ENST00000373979.2
ENST00000507706.1
ENST00000444780.2
ENST00000492680.2
TCP11
t-complex 11, testis-specific
chr6_+_142622991 1.33 ENST00000230173.6
ENST00000367608.2
GPR126
G protein-coupled receptor 126
chr19_-_42927251 1.32 ENST00000597001.1
LIPE
lipase, hormone-sensitive
chr12_-_13256593 1.32 ENST00000542415.1
ENST00000324458.8
GSG1
germ cell associated 1
chrX_+_2670153 1.29 ENST00000509484.2
XG
Xg blood group
chr19_-_18902106 1.25 ENST00000542601.2
ENST00000425807.1
ENST00000222271.2
COMP
cartilage oligomeric matrix protein
chr16_+_89696692 1.25 ENST00000261615.4
DPEP1
dipeptidase 1 (renal)
chr16_+_66400533 1.20 ENST00000341529.3
CDH5
cadherin 5, type 2 (vascular endothelium)
chr4_+_24797085 1.19 ENST00000382120.3
SOD3
superoxide dismutase 3, extracellular
chr20_+_56136136 1.16 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr21_+_19617140 1.14 ENST00000299295.2
ENST00000338326.3
CHODL
chondrolectin
chr15_-_67351586 1.14 ENST00000558071.1
RP11-798K3.2
RP11-798K3.2
chr3_+_157261116 1.13 ENST00000468043.1
ENST00000459838.1
ENST00000461040.1
ENST00000449199.2
ENST00000426338.2
C3orf55
chromosome 3 open reading frame 55
chr18_+_6729725 1.13 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28
Rho GTPase activating protein 28
chr11_+_60383204 1.13 ENST00000412599.1
ENST00000320202.4
LINC00301
long intergenic non-protein coding RNA 301
chr3_+_52828805 1.11 ENST00000416872.2
ENST00000449956.2
ITIH3
inter-alpha-trypsin inhibitor heavy chain 3
chrX_-_70326455 1.11 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr12_+_7169887 1.10 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr2_+_21346789 1.09 ENST00000405799.1
TDRD15
tudor domain containing 15
chr19_+_33210645 1.08 ENST00000444215.2
TDRD12
tudor domain containing 12
chr17_+_41006095 1.08 ENST00000591562.1
ENST00000588033.1
AOC3
amine oxidase, copper containing 3
chr19_+_8429031 1.07 ENST00000301455.2
ENST00000541807.1
ENST00000393962.2
ANGPTL4
angiopoietin-like 4
chr12_-_8815404 1.06 ENST00000359478.2
ENST00000396549.2
MFAP5
microfibrillar associated protein 5
chr11_-_5531215 1.04 ENST00000311659.4
UBQLN3
ubiquilin 3
chrX_-_52260355 1.03 ENST00000375602.1
ENST00000399800.3
XAGE1A
X antigen family, member 1A
chr1_+_212797789 1.03 ENST00000294829.3
FAM71A
family with sequence similarity 71, member A
chrX_+_52511761 1.01 ENST00000399795.3
ENST00000375589.1
XAGE1C
X antigen family, member 1C
chrX_-_133119670 1.00 ENST00000394299.2
GPC3
glypican 3
chr18_+_6729698 1.00 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr4_-_185820602 0.97 ENST00000515864.1
ENST00000507183.1
RP11-701P16.4
long intergenic non-protein coding RNA 1093
chr4_-_144940477 0.96 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
GYPB
glycophorin B (MNS blood group)
chr7_+_73245193 0.95 ENST00000340958.2
CLDN4
claudin 4
chr12_-_53045948 0.95 ENST00000309680.3
KRT2
keratin 2
chr5_-_138842286 0.95 ENST00000515823.1
ECSCR
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr15_-_62457480 0.94 ENST00000380392.3
C2CD4B
C2 calcium-dependent domain containing 4B
chr9_-_34729457 0.93 ENST00000378788.3
FAM205A
family with sequence similarity 205, member A
chr13_+_102104952 0.92 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr19_+_39897943 0.92 ENST00000600033.1
ZFP36
ZFP36 ring finger protein
chr7_-_99573677 0.90 ENST00000292401.4
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr11_-_57158109 0.88 ENST00000525955.1
ENST00000533605.1
ENST00000311862.5
PRG2
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
chr12_-_23737534 0.88 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr9_-_34710066 0.86 ENST00000378792.1
ENST00000259607.2
CCL21
chemokine (C-C motif) ligand 21
chr15_+_40643227 0.86 ENST00000448599.2
PHGR1
proline/histidine/glycine-rich 1
chr1_-_110306562 0.85 ENST00000369805.3
EPS8L3
EPS8-like 3
chr2_-_20425158 0.85 ENST00000381150.1
SDC1
syndecan 1
chr6_+_44184653 0.85 ENST00000573382.2
ENST00000576476.1
RP1-302G2.5
RP1-302G2.5
chr4_-_155511887 0.84 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr11_-_5531159 0.83 ENST00000445998.1
UBQLN3
ubiquilin 3
chr6_-_35109145 0.83 ENST00000373974.4
ENST00000244645.3
TCP11
t-complex 11, testis-specific
chr19_-_375970 0.83 ENST00000346878.2
THEG
theg spermatid protein
chr6_+_144471643 0.82 ENST00000367568.4
STX11
syntaxin 11
chrX_+_52238810 0.82 ENST00000437949.2
ENST00000375616.1
XAGE1B
X antigen family, member 1B
chr17_+_38599693 0.81 ENST00000542955.1
ENST00000269593.4
IGFBP4
insulin-like growth factor binding protein 4
chrX_-_71526999 0.80 ENST00000453707.2
ENST00000373619.3
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chrX_-_52533139 0.80 ENST00000374959.3
XAGE1D
X antigen family, member 1D
chrX_-_52546189 0.79 ENST00000375570.1
ENST00000429372.2
XAGE1E
X antigen family, member 1E
chr3_-_124560257 0.79 ENST00000496703.1
ITGB5
integrin, beta 5
chr17_+_34312621 0.78 ENST00000591669.1
CTB-186H2.3
Uncharacterized protein
chr17_+_79989500 0.78 ENST00000306897.4
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chrX_+_52511925 0.77 ENST00000375588.1
XAGE1C
X antigen family, member 1C
chr3_+_140396881 0.77 ENST00000286349.3
TRIM42
tripartite motif containing 42
chrX_-_52260199 0.77 ENST00000375600.1
XAGE1A
X antigen family, member 1A
chr11_+_1860832 0.76 ENST00000252898.7
TNNI2
troponin I type 2 (skeletal, fast)
chrX_-_153599578 0.76 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr14_+_32414059 0.75 ENST00000553330.1
RP11-187E13.1
Uncharacterized protein
chrX_+_140096761 0.75 ENST00000370530.1
SPANXB1
SPANX family, member B1
chr2_+_217498105 0.75 ENST00000233809.4
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr15_-_76005170 0.75 ENST00000308508.5
CSPG4
chondroitin sulfate proteoglycan 4
chr4_+_119810134 0.75 ENST00000434046.2
SYNPO2
synaptopodin 2
chr20_-_590944 0.75 ENST00000246080.3
TCF15
transcription factor 15 (basic helix-loop-helix)
chr1_-_154458520 0.75 ENST00000486773.1
SHE
Src homology 2 domain containing E
chr6_+_126661253 0.74 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
CENPW
centromere protein W
chrX_-_52533295 0.74 ENST00000375578.1
ENST00000396497.3
XAGE1D
X antigen family, member 1D
chr17_-_48278983 0.74 ENST00000225964.5
COL1A1
collagen, type I, alpha 1
chr4_+_119809984 0.74 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2
synaptopodin 2
chr20_+_43803517 0.73 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr14_+_63671577 0.72 ENST00000555125.1
RHOJ
ras homolog family member J
chr11_-_65793948 0.72 ENST00000312106.5
CATSPER1
cation channel, sperm associated 1
chr1_+_41707996 0.72 ENST00000425554.1
RP11-399E6.1
RP11-399E6.1
chr12_-_57634475 0.72 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr18_+_42277095 0.71 ENST00000591940.1
SETBP1
SET binding protein 1
chr6_+_35744367 0.71 ENST00000360454.2
ENST00000403376.3
CLPSL2
colipase-like 2
chr1_-_22215192 0.71 ENST00000374673.3
HSPG2
heparan sulfate proteoglycan 2
chrX_-_47489244 0.70 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP
complement factor properdin
chr20_+_59654146 0.70 ENST00000441660.1
RP5-827L5.1
RP5-827L5.1
chr19_+_39279838 0.70 ENST00000314980.4
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr1_+_159409512 0.70 ENST00000423932.3
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr2_+_177502438 0.70 ENST00000443670.1
AC017048.4
long intergenic non-protein coding RNA 1117
chrX_-_52546033 0.70 ENST00000375567.3
XAGE1E
X antigen family, member 1E
chr12_+_12878829 0.69 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr20_+_12930980 0.69 ENST00000432244.1
RP11-157E14.1
RP11-157E14.1
chr22_-_21387127 0.69 ENST00000426145.1
SLC7A4
solute carrier family 7, member 4
chr2_-_20424844 0.68 ENST00000403076.1
ENST00000254351.4
SDC1
syndecan 1
chr12_-_7244469 0.68 ENST00000538050.1
ENST00000536053.2
C1R
complement component 1, r subcomponent
chr2_+_238165734 0.68 ENST00000445534.2
AC112715.2
Uncharacterized protein
chrX_-_151938171 0.67 ENST00000393902.3
ENST00000417212.1
ENST00000370278.3
MAGEA3
melanoma antigen family A, 3
chr16_+_31483374 0.67 ENST00000394863.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr3_-_120169828 0.67 ENST00000424703.2
ENST00000469005.1
FSTL1
follistatin-like 1
chr17_+_6926339 0.67 ENST00000293805.5
BCL6B
B-cell CLL/lymphoma 6, member B
chr16_+_31483451 0.66 ENST00000565360.1
ENST00000361773.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr12_-_13248562 0.66 ENST00000457134.2
ENST00000537302.1
GSG1
germ cell associated 1
chr11_+_844067 0.66 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
TSPAN4
tetraspanin 4
chr11_+_57365150 0.66 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr16_+_89238149 0.65 ENST00000289746.2
CDH15
cadherin 15, type 1, M-cadherin (myotubule)
chr4_+_123300664 0.65 ENST00000388725.2
ADAD1
adenosine deaminase domain containing 1 (testis-specific)
chr17_-_39928106 0.65 ENST00000540235.1
JUP
junction plakoglobin
chrX_-_103499602 0.65 ENST00000372588.4
ESX1
ESX homeobox 1
chr14_-_94970559 0.64 ENST00000556881.1
SERPINA12
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr8_-_23712312 0.64 ENST00000290271.2
STC1
stanniocalcin 1
chr19_-_14016877 0.63 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
C19orf57
chromosome 19 open reading frame 57
chr15_+_59397298 0.63 ENST00000559622.1
CCNB2
cyclin B2
chr8_+_22102611 0.63 ENST00000306433.4
POLR3D
polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
chr10_+_71211212 0.63 ENST00000373290.2
TSPAN15
tetraspanin 15
chr8_-_13134045 0.62 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr4_-_75719896 0.62 ENST00000395743.3
BTC
betacellulin
chr17_+_6926381 0.62 ENST00000576705.1
BCL6B
B-cell CLL/lymphoma 6, member B
chr15_+_88795953 0.62 ENST00000569588.1
NTRK3-AS1
NTRK3 antisense RNA 1
chr1_-_120311517 0.62 ENST00000369406.3
ENST00000544913.2
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
chr15_-_101084446 0.62 ENST00000538112.2
ENST00000559639.1
ENST00000558884.2
CERS3
ceramide synthase 3
chr15_-_101084547 0.62 ENST00000394113.1
CERS3
ceramide synthase 3
chr5_+_135385202 0.60 ENST00000514554.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chrX_-_71526813 0.60 ENST00000246139.5
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr13_+_31480843 0.59 ENST00000428944.1
MEDAG
mesenteric estrogen-dependent adipogenesis
chr16_-_86383240 0.59 ENST00000595169.1
ENST00000598994.1
ENST00000599619.1
ENST00000599664.1
LINC00917
long intergenic non-protein coding RNA 917
chr15_-_90358564 0.59 ENST00000559874.1
ANPEP
alanyl (membrane) aminopeptidase
chrX_+_153813407 0.59 ENST00000443287.2
ENST00000333128.3
CTAG1A
cancer/testis antigen 1A
chr18_-_61329118 0.57 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr1_-_155112883 0.57 ENST00000368399.1
ENST00000368400.4
ENST00000341298.3
DPM3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr1_+_152483278 0.57 ENST00000334269.2
LCE5A
late cornified envelope 5A
chr4_-_681114 0.56 ENST00000503156.1
MFSD7
major facilitator superfamily domain containing 7
chr19_+_35630344 0.56 ENST00000455515.2
FXYD1
FXYD domain containing ion transport regulator 1
chr19_-_35626104 0.56 ENST00000310123.3
ENST00000392225.3
LGI4
leucine-rich repeat LGI family, member 4
chr19_-_51334769 0.56 ENST00000596931.1
ENST00000416184.1
ENST00000301421.2
ENST00000598239.1
KLK15
kallikrein-related peptidase 15
chr21_-_40032581 0.56 ENST00000398919.2
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr19_+_42811093 0.56 ENST00000595750.1
PRR19
proline rich 19
chr16_-_8962853 0.55 ENST00000565287.1
ENST00000311052.5
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr7_-_4923259 0.55 ENST00000536091.1
RADIL
Ras association and DIL domains
chr12_-_21927736 0.55 ENST00000240662.2
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr8_-_144699628 0.55 ENST00000529048.1
ENST00000529064.1
TSTA3
tissue specific transplantation antigen P35B
chr17_+_39968926 0.55 ENST00000585664.1
ENST00000585922.1
ENST00000429461.1
FKBP10
FK506 binding protein 10, 65 kDa
chr21_-_38445470 0.55 ENST00000399098.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_-_148580563 0.55 ENST00000476773.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr1_-_242162375 0.55 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr17_+_34087888 0.54 ENST00000586491.1
ENST00000588628.1
ENST00000285023.4
C17orf50
chromosome 17 open reading frame 50
chr3_+_57094469 0.54 ENST00000334325.1
SPATA12
spermatogenesis associated 12
chr11_+_844406 0.54 ENST00000397404.1
TSPAN4
tetraspanin 4
chr3_+_42892458 0.54 ENST00000494619.1
ACKR2
atypical chemokine receptor 2
chr7_+_45197383 0.54 ENST00000242249.4
ENST00000496212.1
ENST00000481345.1
RAMP3
receptor (G protein-coupled) activity modifying protein 3
chr1_+_16083098 0.54 ENST00000496928.2
ENST00000508310.1
FBLIM1
filamin binding LIM protein 1
chr1_+_27113963 0.54 ENST00000430292.1
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr6_-_36304660 0.53 ENST00000437635.2
C6orf222
chromosome 6 open reading frame 222
chr9_+_35792151 0.53 ENST00000342694.2
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr22_+_38071615 0.53 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr2_-_177502659 0.53 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr15_-_74659978 0.53 ENST00000541301.1
ENST00000416978.1
ENST00000268053.6
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr1_+_16083123 0.53 ENST00000510393.1
ENST00000430076.1
FBLIM1
filamin binding LIM protein 1
chr12_+_3068466 0.53 ENST00000358409.2
TEAD4
TEA domain family member 4
chr13_+_102104980 0.52 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr19_-_16008880 0.52 ENST00000011989.7
ENST00000221700.6
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
chr12_+_7072354 0.52 ENST00000537269.1
U47924.27
U47924.27
chr11_-_68780701 0.52 ENST00000320913.6
MRGPRF
MAS-related GPR, member F
chr22_-_20138302 0.52 ENST00000540078.1
ENST00000439765.2
AC006547.14
uncharacterized protein LOC388849
chrX_+_30260054 0.52 ENST00000378982.2
MAGEB4
melanoma antigen family B, 4
chr13_-_111214015 0.52 ENST00000267328.3
RAB20
RAB20, member RAS oncogene family
chr8_+_22414182 0.52 ENST00000524057.1
SORBS3
sorbin and SH3 domain containing 3
chr6_+_138725343 0.51 ENST00000607197.1
ENST00000367697.3
HEBP2
heme binding protein 2
chr16_-_1843720 0.51 ENST00000415638.3
ENST00000215539.3
IGFALS
insulin-like growth factor binding protein, acid labile subunit
chr1_+_6511651 0.51 ENST00000434576.1
ESPN
espin
chr11_-_117103208 0.51 ENST00000320934.3
ENST00000530269.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr18_-_14543145 0.51 ENST00000358970.5
POTEC
POTE ankyrin domain family, member C
chr7_+_130020932 0.50 ENST00000484324.1
CPA1
carboxypeptidase A1 (pancreatic)
chr12_-_55042140 0.50 ENST00000293371.6
ENST00000456047.2
DCD
dermcidin
chr14_-_21566731 0.50 ENST00000360947.3
ZNF219
zinc finger protein 219
chr14_+_63671105 0.49 ENST00000316754.3
RHOJ
ras homolog family member J
chr19_+_41107249 0.49 ENST00000396819.3
LTBP4
latent transforming growth factor beta binding protein 4
chr20_+_43029911 0.48 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4, alpha
chr3_-_58196688 0.48 ENST00000486455.1
DNASE1L3
deoxyribonuclease I-like 3
chr17_-_63822563 0.48 ENST00000317442.8
CEP112
centrosomal protein 112kDa
chr19_+_1941117 0.48 ENST00000255641.8
CSNK1G2
casein kinase 1, gamma 2
chr11_-_114466471 0.48 ENST00000424261.2
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr8_+_22428457 0.48 ENST00000517962.1
SORBS3
sorbin and SH3 domain containing 3
chr1_-_57045228 0.48 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr12_-_10151773 0.47 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.7 2.1 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.6 1.9 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.5 2.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.5 1.5 GO:0048627 myoblast development(GO:0048627)
0.5 1.4 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.4 1.3 GO:0016999 antibiotic metabolic process(GO:0016999)
0.4 1.5 GO:0030185 nitric oxide transport(GO:0030185)
0.4 1.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.3 1.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.3 2.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.3 0.9 GO:0035759 mesangial cell-matrix adhesion(GO:0035759) regulation of dendritic cell dendrite assembly(GO:2000547)
0.3 1.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.3 0.8 GO:1903717 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.3 0.8 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.2 1.9 GO:0071105 response to interleukin-11(GO:0071105)
0.2 0.7 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 0.7 GO:0044691 tooth eruption(GO:0044691)
0.2 0.9 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.2 0.5 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.2 0.5 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.2 0.5 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.2 0.8 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.1 1.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.6 GO:0002215 defense response to nematode(GO:0002215)
0.1 1.0 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.1 0.6 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.6 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1 0.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.5 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.4 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.7 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.6 GO:1904141 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 0.4 GO:0045554 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.1 1.0 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.5 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) renal water absorption(GO:0070295)
0.1 0.3 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.3 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.4 GO:0052361 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 1.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.3 GO:0060988 lipid tube assembly(GO:0060988)
0.1 0.3 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.7 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.6 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.1 0.3 GO:2000452 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.1 0.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.5 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 1.0 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.0 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.5 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 1.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.6 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 1.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.1 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.1 0.6 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.2 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.2 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.4 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.5 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.3 GO:0051546 keratinocyte migration(GO:0051546)
0.1 0.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.3 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.9 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.3 GO:0097327 response to antineoplastic agent(GO:0097327)
0.1 0.4 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.1 0.7 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 1.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.9 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.3 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.1 GO:0003274 endocardial cushion fusion(GO:0003274)
0.1 0.2 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.3 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.1 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.3 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 1.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.6 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.4 GO:1902231 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.8 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.8 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 1.0 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 1.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0045575 basophil activation(GO:0045575)
0.0 0.4 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) response to thyrotropin-releasing hormone(GO:1905225)
0.0 2.2 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.6 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 1.2 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.3 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 1.0 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.7 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:0003095 pressure natriuresis(GO:0003095) vitamin E metabolic process(GO:0042360)
0.0 0.3 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 1.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.9 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.5 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.4 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.6 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.5 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.3 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.4 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0048863 stem cell differentiation(GO:0048863)
0.0 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.5 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 1.0 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.3 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.0 0.8 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.6 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.7 GO:0007620 copulation(GO:0007620)
0.0 0.7 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.7 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.6 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.0 0.1 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.0 0.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.0 GO:0070054 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.0 0.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.9 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.6 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0044107 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.0 0.3 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.3 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.9 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 1.8 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.9 GO:0043029 T cell homeostasis(GO:0043029)
0.0 3.2 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.1 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 1.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0043366 beta selection(GO:0043366)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.5 GO:0046688 response to copper ion(GO:0046688)
0.0 0.4 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.8 GO:0008347 glial cell migration(GO:0008347)
0.0 0.0 GO:0070945 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944) neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 1.1 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.5 GO:0030252 growth hormone secretion(GO:0030252)
0.0 1.1 GO:0030317 sperm motility(GO:0030317)
0.0 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.8 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.5 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 1.3 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.5 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.4 GO:0014009 glial cell proliferation(GO:0014009)
0.0 0.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.6 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.3 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.0 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.0 GO:2000698 positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.5 GO:0097352 autophagosome maturation(GO:0097352)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 1.2 GO:1990923 PET complex(GO:1990923)
0.2 0.7 GO:0005584 collagen type I trimer(GO:0005584)
0.2 0.8 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.2 0.8 GO:0031523 Myb complex(GO:0031523)
0.2 1.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.2 0.6 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 2.2 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.4 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.6 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.5 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.7 GO:0036128 CatSper complex(GO:0036128)
0.1 0.8 GO:0031941 filamentous actin(GO:0031941)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 1.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 2.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.7 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.0 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.8 GO:0005861 troponin complex(GO:0005861)
0.0 0.6 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 4.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.6 GO:0045120 pronucleus(GO:0045120)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 2.0 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 1.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 3.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0031970 organelle envelope lumen(GO:0031970)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 1.6 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0030478 actin cap(GO:0030478)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.4 1.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.4 1.2 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.3 1.7 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.3 1.1 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3 1.0 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.2 1.5 GO:0030492 hemoglobin binding(GO:0030492)
0.2 0.8 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 0.6 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.2 0.6 GO:0050577 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.2 0.5 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.2 0.5 GO:0030395 lactose binding(GO:0030395)
0.2 0.5 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.2 0.6 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.6 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.6 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 2.2 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.7 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 1.3 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.4 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.4 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 1.3 GO:0034235 GPI anchor binding(GO:0034235) metallodipeptidase activity(GO:0070573)
0.1 1.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 1.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.3 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.1 0.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 3.0 GO:0031005 filamin binding(GO:0031005)
0.1 0.4 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.6 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.5 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.4 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.1 1.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.8 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.8 GO:0031014 troponin T binding(GO:0031014)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 2.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.4 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.2 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 3.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.9 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.5 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.5 GO:0005113 patched binding(GO:0005113)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.7 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.7 GO:0070330 aromatase activity(GO:0070330)
0.0 0.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.1 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 1.0 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.2 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 7.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.9 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 1.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.6 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 5.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 2.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 3.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 2.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 2.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.0 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.9 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 2.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 3.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.8 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.2 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 2.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors