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Illumina Body Map 2, young vs old

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Results for KLF6

Z-value: 1.41

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Transcription factors associated with KLF6

Gene Symbol Gene ID Gene Info
ENSG00000067082.10 Kruppel like factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF6hg19_v2_chr10_-_3827371_3827386-0.144.5e-01Click!

Activity profile of KLF6 motif

Sorted Z-values of KLF6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_102505468 1.39 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
paired box 2
chr2_+_105471969 0.87 ENST00000361360.2
POU class 3 homeobox 3
chr1_-_156051789 0.86 ENST00000532414.2
mex-3 RNA binding family member A
chr16_+_67465016 0.78 ENST00000326152.5
hydroxysteroid (11-beta) dehydrogenase 2
chr14_+_94640633 0.78 ENST00000304338.3
protein phosphatase 4, regulatory subunit 4
chr11_+_94706804 0.77 ENST00000335080.5
lysine (K)-specific demethylase 4D
chr20_+_31350184 0.76 ENST00000328111.2
ENST00000353855.2
ENST00000348286.2
DNA (cytosine-5-)-methyltransferase 3 beta
chr17_+_40932610 0.74 ENST00000246914.5
WNK lysine deficient protein kinase 4
chr2_-_219925189 0.72 ENST00000295731.6
indian hedgehog
chr1_+_169075554 0.69 ENST00000367815.4
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr7_-_143105941 0.69 ENST00000275815.3
EPH receptor A1
chr11_+_94706973 0.68 ENST00000536741.1
lysine (K)-specific demethylase 4D
chr1_-_204121102 0.63 ENST00000367202.4
ethanolamine kinase 2
chr4_-_77819002 0.60 ENST00000334306.2
sosondowah ankyrin repeat domain family member B
chr6_-_110500905 0.55 ENST00000392587.2
WAS protein family, member 1
chr17_-_60885700 0.54 ENST00000583600.1
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr14_+_94640671 0.53 ENST00000328839.3
protein phosphatase 4, regulatory subunit 4
chr6_-_110500826 0.52 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WAS protein family, member 1
chr17_-_60885659 0.52 ENST00000311269.5
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr7_-_27239703 0.52 ENST00000222753.4
homeobox A13
chr3_+_38495333 0.51 ENST00000352511.4
activin A receptor, type IIB
chr2_-_220408430 0.51 ENST00000243776.6
chondroitin polymerizing factor
chr15_+_41136586 0.50 ENST00000431806.1
serine peptidase inhibitor, Kunitz type 1
chr2_+_220408724 0.50 ENST00000421791.1
ENST00000373883.3
ENST00000451952.1
transmembrane protein 198
chr12_-_103352144 0.50 ENST00000551337.1
phenylalanine hydroxylase
chr11_-_2160180 0.49 ENST00000381406.4
insulin-like growth factor 2 (somatomedin A)
chr12_+_52445191 0.49 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
nuclear receptor subfamily 4, group A, member 1
chr18_+_55102917 0.49 ENST00000491143.2
one cut homeobox 2
chr9_-_6645628 0.48 ENST00000321612.6
glycine dehydrogenase (decarboxylating)
chr6_-_110501200 0.47 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WAS protein family, member 1
chr15_+_41136216 0.47 ENST00000562057.1
ENST00000344051.4
serine peptidase inhibitor, Kunitz type 1
chr17_+_79679369 0.46 ENST00000350690.5
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr17_-_60885645 0.46 ENST00000544856.2
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr19_+_4153598 0.46 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
cAMP responsive element binding protein 3-like 3
chr11_+_71238313 0.46 ENST00000398536.4
keratin associated protein 5-7
chr11_+_45907177 0.46 ENST00000241014.2
mitogen-activated protein kinase 8 interacting protein 1
chr1_+_6845578 0.45 ENST00000467404.2
ENST00000439411.2
calmodulin binding transcription activator 1
chr2_+_158733088 0.44 ENST00000605860.1
uridine phosphorylase 2
chr2_+_42275153 0.44 ENST00000294964.5
protein kinase domain containing, cytoplasmic
chr20_+_49348109 0.43 ENST00000396039.1
par-6 family cell polarity regulator beta
chr16_+_68679193 0.43 ENST00000581171.1
cadherin 3, type 1, P-cadherin (placental)
chr17_+_79008940 0.42 ENST00000392411.3
ENST00000575989.1
ENST00000321280.7
ENST00000428708.2
ENST00000575712.1
ENST00000575245.1
ENST00000435091.3
ENST00000321300.6
BAI1-associated protein 2
chr4_+_184426147 0.42 ENST00000302327.3
inhibitor of growth family, member 2
chr2_-_220436248 0.42 ENST00000265318.4
obscurin-like 1
chr2_-_170219079 0.41 ENST00000263816.3
low density lipoprotein receptor-related protein 2
chr17_+_9548845 0.40 ENST00000570475.1
ENST00000285199.7
ubiquitin specific peptidase 43
chr15_+_41136369 0.39 ENST00000563656.1
serine peptidase inhibitor, Kunitz type 1
chr15_+_41851211 0.39 ENST00000263798.3
TYRO3 protein tyrosine kinase
chr7_-_150864635 0.39 ENST00000297537.4
gastrulation brain homeobox 1
chr16_+_68678892 0.38 ENST00000429102.2
cadherin 3, type 1, P-cadherin (placental)
chr17_-_46703826 0.38 ENST00000550387.1
ENST00000311177.5
homeobox B9
chr16_+_68678739 0.37 ENST00000264012.4
cadherin 3, type 1, P-cadherin (placental)
chr20_-_48099182 0.37 ENST00000371741.4
potassium voltage-gated channel, Shab-related subfamily, member 1
chr17_+_42081914 0.36 ENST00000293404.3
ENST00000589767.1
N-acetylglutamate synthase
chr11_+_394196 0.36 ENST00000331563.2
ENST00000531857.1
plakophilin 3
chr12_-_96184533 0.36 ENST00000343702.4
ENST00000344911.4
netrin 4
chr7_+_128828713 0.36 ENST00000249373.3
smoothened, frizzled family receptor
chr6_-_82462425 0.36 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
family with sequence similarity 46, member A
chr11_+_6255995 0.36 ENST00000533426.1
cyclic nucleotide gated channel alpha 4
chr19_-_49568311 0.35 ENST00000595857.1
ENST00000451356.2
neurotrophin 4
chr13_-_52027134 0.35 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chr4_-_153700864 0.35 ENST00000304337.2
tigger transposable element derived 4
chr12_+_56473628 0.34 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chrX_-_139587225 0.34 ENST00000370536.2
SRY (sex determining region Y)-box 3
chr15_+_41136263 0.34 ENST00000568823.1
serine peptidase inhibitor, Kunitz type 1
chr1_-_114696472 0.33 ENST00000393296.1
ENST00000369547.1
ENST00000610222.1
synaptotagmin VI
chr4_-_39529049 0.33 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
UDP-glucose 6-dehydrogenase
chr12_-_50222187 0.33 ENST00000335999.6
NCK-associated protein 5-like
chr1_+_6508571 0.32 ENST00000478323.1
espin
chr15_-_83316711 0.32 ENST00000568128.1
cytoplasmic polyadenylation element binding protein 1
chr6_-_110501126 0.32 ENST00000368938.1
WAS protein family, member 1
chr1_-_156698591 0.32 ENST00000368219.1
interferon stimulated exonuclease gene 20kDa-like 2
chr14_-_23451845 0.32 ENST00000262713.2
ajuba LIM protein
chr7_+_120628731 0.32 ENST00000310396.5
cadherin-like and PC-esterase domain containing 1
chr5_-_2751762 0.32 ENST00000302057.5
ENST00000382611.6
iroquois homeobox 2
chr2_+_27371866 0.32 ENST00000296096.5
transcription factor 23
chr4_-_40631859 0.32 ENST00000295971.7
ENST00000319592.4
RNA binding motif protein 47
chr14_-_30396948 0.31 ENST00000331968.5
protein kinase D1
chr6_+_21593972 0.31 ENST00000244745.1
ENST00000543472.1
SRY (sex determining region Y)-box 4
chr1_+_6845497 0.31 ENST00000473578.1
ENST00000557126.1
calmodulin binding transcription activator 1
chr11_-_108464465 0.30 ENST00000525344.1
exophilin 5
chr2_-_27341765 0.30 ENST00000405600.1
cell growth regulator with EF-hand domain 1
chr22_-_38484922 0.30 ENST00000428572.1
BAI1-associated protein 2-like 2
chr12_-_96184913 0.30 ENST00000538383.1
netrin 4
chr19_-_31840438 0.29 ENST00000240587.4
teashirt zinc finger homeobox 3
chr20_+_30555805 0.29 ENST00000562532.2
XK, Kell blood group complex subunit-related family, member 7
chr15_-_56035177 0.29 ENST00000389286.4
ENST00000561292.1
protogenin
chr17_+_42634844 0.29 ENST00000315323.3
frizzled family receptor 2
chr17_-_72919317 0.29 ENST00000319642.1
Usher syndrome 1G (autosomal recessive)
chr17_+_36508111 0.28 ENST00000331159.5
ENST00000577233.1
suppressor of cytokine signaling 7
chr22_+_45680822 0.28 ENST00000216211.4
ENST00000396082.2
uroplakin 3A
chr17_-_7145475 0.28 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABA(A) receptor-associated protein
chr2_-_220408260 0.27 ENST00000373891.2
chondroitin polymerizing factor
chrY_-_25345070 0.27 ENST00000382510.4
ENST00000426000.2
ENST00000540248.1
ENST00000405239.1
deleted in azoospermia 1
chr1_-_6321035 0.27 ENST00000377893.2
G protein-coupled receptor 153
chr5_-_159739532 0.27 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
cyclin J-like
chr9_-_115249484 0.27 ENST00000457681.1
chromosome 9 open reading frame 147
chr14_+_89029323 0.26 ENST00000554602.1
zinc finger CCCH-type containing 14
chr12_+_110152033 0.26 ENST00000538780.1
family with sequence similarity 222, member A
chr1_+_240255166 0.26 ENST00000319653.9
formin 2
chr14_+_89029336 0.26 ENST00000556945.1
ENST00000556158.1
ENST00000557607.1
zinc finger CCCH-type containing 14
chr1_+_114522049 0.26 ENST00000369551.1
ENST00000320334.4
olfactomedin-like 3
chr5_+_109025067 0.25 ENST00000261483.4
mannosidase, alpha, class 2A, member 1
chr11_+_45918092 0.25 ENST00000395629.2
mitogen-activated protein kinase 8 interacting protein 1
chr22_+_38004832 0.25 ENST00000405147.3
ENST00000429218.1
ENST00000325180.8
ENST00000337437.4
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr22_+_38004942 0.25 ENST00000439161.1
ENST00000449944.1
ENST00000411501.1
ENST00000453208.1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr22_-_45405829 0.25 ENST00000414269.1
PHD finger protein 21B
chr7_+_106685079 0.25 ENST00000265717.4
protein kinase, cAMP-dependent, regulatory, type II, beta
chr22_+_38004723 0.24 ENST00000381756.5
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr2_-_211036051 0.24 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KAT8 regulatory NSL complex subunit 1-like
chr20_+_34680698 0.24 ENST00000447825.1
erythrocyte membrane protein band 4.1-like 1
chr9_+_2017063 0.24 ENST00000457226.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr17_+_30771279 0.24 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr6_+_31588478 0.24 ENST00000376007.4
ENST00000376033.2
proline-rich coiled-coil 2A
chr1_+_33219592 0.24 ENST00000373481.3
KIAA1522
chr10_+_114709999 0.24 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_-_27341966 0.24 ENST00000402394.1
ENST00000402550.1
ENST00000260595.5
cell growth regulator with EF-hand domain 1
chr14_+_89029253 0.24 ENST00000251038.5
ENST00000359301.3
ENST00000302216.8
zinc finger CCCH-type containing 14
chr7_+_138145145 0.24 ENST00000415680.2
tripartite motif containing 24
chr17_-_56565736 0.23 ENST00000323777.3
heat shock transcription factor family member 5
chr5_-_159739483 0.23 ENST00000519673.1
ENST00000541762.1
cyclin J-like
chr15_-_76352069 0.23 ENST00000305435.10
ENST00000563910.1
neuregulin 4
chr17_-_62340581 0.23 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
testis expressed 2
chr12_+_57482665 0.23 ENST00000300131.3
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr17_+_41177220 0.23 ENST00000587250.2
ENST00000544533.1
Rho family GTPase 2
chr15_-_83316254 0.23 ENST00000567678.1
ENST00000450751.2
cytoplasmic polyadenylation element binding protein 1
chr15_-_53082178 0.23 ENST00000305901.5
one cut homeobox 1
chr10_+_105253661 0.22 ENST00000369780.4
neuralized E3 ubiquitin protein ligase 1
chr19_-_55865908 0.22 ENST00000590900.1
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr14_-_37051798 0.22 ENST00000258829.5
NK2 homeobox 8
chr18_-_51750948 0.22 ENST00000583046.1
ENST00000398398.2
methyl-CpG binding domain protein 2
chr4_-_40632140 0.22 ENST00000514782.1
RNA binding motif protein 47
chr2_+_210636697 0.22 ENST00000439458.1
ENST00000272845.6
unc-80 homolog (C. elegans)
chr1_-_156698181 0.22 ENST00000313146.6
interferon stimulated exonuclease gene 20kDa-like 2
chr1_+_68150744 0.21 ENST00000370986.4
ENST00000370985.3
growth arrest and DNA-damage-inducible, alpha
chr4_+_52709229 0.21 ENST00000334635.5
ENST00000381441.3
ENST00000381437.4
DCN1, defective in cullin neddylation 1, domain containing 4
chr7_-_27213893 0.21 ENST00000283921.4
homeobox A10
chr2_-_219850277 0.21 ENST00000295727.1
FEV (ETS oncogene family)
chr6_+_36164487 0.21 ENST00000357641.6
bromodomain and PHD finger containing, 3
chr5_+_137801160 0.21 ENST00000239938.4
early growth response 1
chr14_+_101293687 0.21 ENST00000455286.1
maternally expressed 3 (non-protein coding)
chr4_+_48343339 0.21 ENST00000264313.6
SLAIN motif family, member 2
chrX_+_130192318 0.21 ENST00000370922.1
Rho GTPase activating protein 36
chr3_-_184079382 0.21 ENST00000344937.7
ENST00000423355.2
ENST00000434054.2
ENST00000457512.1
ENST00000265593.4
chloride channel, voltage-sensitive 2
chr16_-_68482394 0.20 ENST00000561749.1
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr11_-_72492903 0.20 ENST00000537947.1
StAR-related lipid transfer (START) domain containing 10
chr11_-_119234876 0.20 ENST00000525735.1
ubiquitin specific peptidase 2
chr4_-_174451370 0.20 ENST00000359562.4
heart and neural crest derivatives expressed 2
chr17_-_37382105 0.20 ENST00000333461.5
SH3 and cysteine rich domain 2
chr10_-_75255668 0.20 ENST00000545874.1
protein phosphatase 3, catalytic subunit, beta isozyme
chr16_-_58231782 0.19 ENST00000565188.1
ENST00000262506.3
casein kinase 2, alpha prime polypeptide
chr9_+_6645887 0.19 ENST00000413145.1
RP11-390F4.6
chr14_-_51411146 0.19 ENST00000532462.1
phosphorylase, glycogen, liver
chr1_+_6673745 0.19 ENST00000377648.4
PHD finger protein 13
chr5_+_86563636 0.19 ENST00000274376.6
RAS p21 protein activator (GTPase activating protein) 1
chr7_-_56101826 0.19 ENST00000421626.1
phosphoserine phosphatase
chr19_+_50084561 0.19 ENST00000246794.5
proline rich Gla (G-carboxyglutamic acid) 2
chr11_+_394145 0.19 ENST00000528036.1
plakophilin 3
chr15_+_52311398 0.19 ENST00000261845.5
mitogen-activated protein kinase 6
chr16_-_68482440 0.19 ENST00000219334.5
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr11_+_64009072 0.19 ENST00000535135.1
ENST00000394540.3
FK506 binding protein 2, 13kDa
chr2_+_64751433 0.19 ENST00000238856.4
ENST00000422803.1
ENST00000238855.7
aftiphilin
chr9_+_128509624 0.19 ENST00000342287.5
ENST00000373487.4
pre-B-cell leukemia homeobox 3
chr12_+_132312931 0.19 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
matrix metallopeptidase 17 (membrane-inserted)
chr16_-_49315731 0.19 ENST00000219197.6
cerebellin 1 precursor
chr16_+_53164956 0.18 ENST00000563410.1
chromodomain helicase DNA binding protein 9
chr17_+_38498594 0.18 ENST00000394081.3
retinoic acid receptor, alpha
chr16_+_53164833 0.18 ENST00000564845.1
chromodomain helicase DNA binding protein 9
chr5_+_42423872 0.18 ENST00000230882.4
ENST00000357703.3
growth hormone receptor
chr18_-_24129367 0.18 ENST00000408011.3
potassium channel tetramerization domain containing 1
chr2_+_203499901 0.18 ENST00000303116.6
ENST00000392238.2
family with sequence similarity 117, member B
chrX_+_21959108 0.18 ENST00000457085.1
spermine synthase
chr19_+_39989535 0.18 ENST00000356433.5
delta-like 3 (Drosophila)
chr11_-_113345842 0.18 ENST00000346454.3
dopamine receptor D2
chr18_+_60190226 0.18 ENST00000269499.5
zinc finger, CCHC domain containing 2
chr1_-_85666688 0.18 ENST00000341460.5
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr19_+_532049 0.18 ENST00000606136.1
cell division cycle 34
chr2_+_150187020 0.17 ENST00000334166.4
LY6/PLAUR domain containing 6
chr15_-_72612470 0.17 ENST00000287202.5
CUGBP, Elav-like family member 6
chr17_-_1389228 0.17 ENST00000438665.2
myosin IC
chr9_-_77643189 0.17 ENST00000376837.3
chromosome 9 open reading frame 41
chr1_-_244615425 0.17 ENST00000366535.3
adenylosuccinate synthase
chr11_-_89224667 0.17 ENST00000393282.2
NADPH oxidase 4
chr10_+_76586348 0.17 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
K(lysine) acetyltransferase 6B
chr14_+_23340822 0.17 ENST00000359591.4
low density lipoprotein receptor-related protein 10
chr7_+_138145076 0.17 ENST00000343526.4
tripartite motif containing 24
chr9_+_131038425 0.17 ENST00000320188.5
ENST00000608796.1
ENST00000419867.2
ENST00000418976.1
SWI5 recombination repair homolog (yeast)
chr17_+_28256874 0.17 ENST00000541045.1
ENST00000536908.2
EF-hand calcium binding domain 5
chr17_+_48638371 0.17 ENST00000360761.4
ENST00000352832.5
ENST00000354983.4
calcium channel, voltage-dependent, T type, alpha 1G subunit
chrX_+_150863596 0.16 ENST00000448726.1
ENST00000538575.1
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr14_-_51411194 0.16 ENST00000544180.2
phosphorylase, glycogen, liver
chr3_-_133969437 0.16 ENST00000460933.1
ENST00000296084.4
receptor-like tyrosine kinase
chr2_+_42795745 0.16 ENST00000406911.1
metastasis associated 1 family, member 3
chr5_-_168006324 0.16 ENST00000522176.1
pantothenate kinase 3
chr7_-_72936531 0.16 ENST00000339594.4
bromodomain adjacent to zinc finger domain, 1B
chr22_+_29279552 0.16 ENST00000544604.2
zinc and ring finger 3
chr16_+_25703274 0.16 ENST00000331351.5
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr16_-_28222797 0.16 ENST00000569951.1
ENST00000565698.1
exportin 6
chrX_+_40944871 0.16 ENST00000378308.2
ENST00000324545.8
ubiquitin specific peptidase 9, X-linked
chr12_-_107487604 0.16 ENST00000008527.5
cryptochrome 1 (photolyase-like)

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0035566 regulation of metanephros size(GO:0035566)
0.3 1.2 GO:0051796 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.2 0.7 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.2 0.9 GO:0072240 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.2 1.5 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.2 0.5 GO:1902356 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 1.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.1 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.1 0.1 GO:0060516 primary prostatic bud elongation(GO:0060516)
0.1 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.5 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.4 GO:0008052 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.7 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.7 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 0.5 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.4 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.4 GO:0046108 uridine metabolic process(GO:0046108)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.3 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.1 0.4 GO:0019230 proprioception(GO:0019230)
0.1 0.3 GO:0035905 N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.4 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.4 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.6 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 0.2 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.3 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.2 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 1.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.5 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.4 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.4 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:1901207 mammary placode formation(GO:0060596) regulation of heart looping(GO:1901207)
0.0 0.1 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.3 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 1.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.3 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.4 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.7 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.2 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.5 GO:0060836 positive regulation of activin receptor signaling pathway(GO:0032927) lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.6 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.2 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.3 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.3 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.3 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.3 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.1 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.3 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.2 GO:0051586 glial cell-derived neurotrophic factor secretion(GO:0044467) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.2 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.2 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.3 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.4 GO:0060068 vagina development(GO:0060068)
0.0 0.1 GO:2000973 midbrain morphogenesis(GO:1904693) regulation of pro-B cell differentiation(GO:2000973)
0.0 0.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.3 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.2 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.6 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.5 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.1 GO:0060028 somatic muscle development(GO:0007525) convergent extension involved in axis elongation(GO:0060028)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.0 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.1 GO:0060434 bronchus morphogenesis(GO:0060434)
0.0 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0042756 drinking behavior(GO:0042756)
0.0 0.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.6 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.2 GO:1901727 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089) protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.0 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.0 GO:0045799 negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.1 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.0 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.2 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.0 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.2 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.0 0.3 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951) positive regulation of inclusion body assembly(GO:0090261)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.0 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.1 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.0 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.2 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 0.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.1 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.0 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.0 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 1.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.7 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.0 1.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 1.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0071458 polycystin complex(GO:0002133) integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 1.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.8 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 0.5 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.2 0.5 GO:0016768 spermine synthase activity(GO:0016768)
0.1 0.4 GO:0008184 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.1 0.4 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.8 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.5 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 0.6 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.4 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.6 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.4 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.5 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.3 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 0.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.7 GO:0005113 patched binding(GO:0005113)
0.0 1.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0048763 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:1990175 EH domain binding(GO:1990175)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.5 GO:0016594 glycine binding(GO:0016594)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.8 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.3 GO:0035173 histone kinase activity(GO:0035173)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.0 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.0 PID EPO PATHWAY EPO signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases