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Illumina Body Map 2, young vs old

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Results for LHX2

Z-value: 0.53

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Transcription factors associated with LHX2

Gene Symbol Gene ID Gene Info
LHX2
ENSG00000106689.6 LIM homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX2hg19_v2_chr9_+_126773880_126773895-0.134.6e-01Click!

Activity profile of LHX2 motif

Sorted Z-values of LHX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_22554680 3.19 ENST00000390451.2
TRAV23DV6
T cell receptor alpha variable 23/delta variable 6
chr9_+_13446472 2.67 ENST00000428006.2
RP11-536O18.1
RP11-536O18.1
chr15_-_51535208 2.54 ENST00000405913.3
ENST00000559878.1
CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr4_-_90756769 2.37 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr6_+_26199737 2.33 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr13_-_99959641 2.23 ENST00000376414.4
GPR183
G protein-coupled receptor 183
chr14_+_22694606 2.17 ENST00000390463.3
TRAV36DV7
T cell receptor alpha variable 36/delta variable 7
chr14_+_22573582 2.05 ENST00000390453.1
TRAV24
T cell receptor alpha variable 24
chr3_+_108541545 2.05 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr15_+_51669513 1.99 ENST00000558426.1
GLDN
gliomedin
chrX_+_99839799 1.85 ENST00000373031.4
TNMD
tenomodulin
chr7_-_38339890 1.82 ENST00000390341.2
TRGV10
T cell receptor gamma variable 10 (non-functional)
chr14_+_56584414 1.76 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr7_+_80253387 1.70 ENST00000438020.1
CD36
CD36 molecule (thrombospondin receptor)
chr3_-_191000172 1.69 ENST00000427544.2
UTS2B
urotensin 2B
chr14_+_23845995 1.63 ENST00000359320.3
CMTM5
CKLF-like MARVEL transmembrane domain containing 5
chr13_-_99910673 1.61 ENST00000397473.2
ENST00000397470.2
GPR18
G protein-coupled receptor 18
chr3_+_108541608 1.60 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr8_-_82395461 1.56 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr14_-_106926724 1.54 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr12_+_6554021 1.49 ENST00000266557.3
CD27
CD27 molecule
chr2_-_89476644 1.48 ENST00000484817.1
IGKV2-24
immunoglobulin kappa variable 2-24
chr5_+_118668846 1.48 ENST00000513374.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr18_+_66465302 1.47 ENST00000360242.5
ENST00000358653.5
CCDC102B
coiled-coil domain containing 102B
chr2_-_175712270 1.43 ENST00000295497.7
ENST00000444394.1
CHN1
chimerin 1
chr7_+_80254279 1.43 ENST00000436384.1
CD36
CD36 molecule (thrombospondin receptor)
chr1_+_160709055 1.39 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7
SLAM family member 7
chr1_+_160709076 1.38 ENST00000359331.4
ENST00000495334.1
SLAMF7
SLAM family member 7
chr4_+_153021899 1.37 ENST00000509332.1
ENST00000504144.1
ENST00000499452.2
RP11-18H21.1
RP11-18H21.1
chr4_-_109541539 1.36 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr13_-_46952645 1.36 ENST00000439642.1
KIAA0226L
KIAA0226-like
chr14_+_22992573 1.36 ENST00000390516.1
TRAJ21
T cell receptor alpha joining 21
chr1_+_84630574 1.33 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr17_-_33864772 1.32 ENST00000361112.4
SLFN12L
schlafen family member 12-like
chr14_+_22631122 1.30 ENST00000390458.3
TRAV29DV5
T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene)
chr1_+_81001398 1.29 ENST00000418041.1
ENST00000443104.1
RP5-887A10.1
RP5-887A10.1
chr11_-_2323089 1.28 ENST00000456145.2
C11orf21
chromosome 11 open reading frame 21
chr6_+_126661253 1.26 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
CENPW
centromere protein W
chr2_-_175712479 1.26 ENST00000443238.1
CHN1
chimerin 1
chr16_+_31271274 1.24 ENST00000287497.8
ENST00000544665.3
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr11_-_104972158 1.22 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr14_-_107211459 1.22 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr3_+_57882061 1.20 ENST00000461354.1
ENST00000466255.1
SLMAP
sarcolemma associated protein
chr12_+_41136144 1.19 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr1_+_160709029 1.16 ENST00000444090.2
ENST00000441662.2
SLAMF7
SLAM family member 7
chr16_+_31213206 1.15 ENST00000561916.2
C16orf98
chromosome 16 open reading frame 98
chr6_-_26199499 1.15 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr13_-_99910620 1.14 ENST00000416594.1
GPR18
G protein-coupled receptor 18
chr1_+_192127578 1.13 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr2_-_89157161 1.11 ENST00000390237.2
IGKC
immunoglobulin kappa constant
chr14_-_78083112 1.10 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr15_-_72521017 1.09 ENST00000561609.1
PKM
pyruvate kinase, muscle
chr14_+_52313833 1.08 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr2_+_87769459 1.07 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr4_+_70796784 1.07 ENST00000246891.4
ENST00000444405.3
CSN1S1
casein alpha s1
chr17_-_295730 1.05 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr3_+_57881966 1.03 ENST00000495364.1
SLMAP
sarcolemma associated protein
chr2_-_112237835 1.02 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr11_-_40315640 1.01 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr11_-_46113756 1.01 ENST00000531959.1
PHF21A
PHD finger protein 21A
chr6_-_26199471 1.00 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr5_-_41794313 0.99 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr4_-_120243545 0.99 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr2_+_90139056 0.96 ENST00000492446.1
IGKV1D-16
immunoglobulin kappa variable 1D-16
chr13_-_19755975 0.94 ENST00000400113.3
TUBA3C
tubulin, alpha 3c
chr2_+_68961934 0.93 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr1_-_153518270 0.92 ENST00000354332.4
ENST00000368716.4
S100A4
S100 calcium binding protein A4
chr8_-_19459993 0.91 ENST00000454498.2
ENST00000520003.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr7_-_38315919 0.90 ENST00000390339.1
TRGJP1
T cell receptor gamma joining P1
chr2_+_68961905 0.90 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr17_-_57229155 0.88 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr7_-_142232071 0.88 ENST00000390364.3
TRBV10-1
T cell receptor beta variable 10-1(gene/pseudogene)
chr1_-_183560011 0.87 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr2_+_68962014 0.85 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr4_+_70916119 0.84 ENST00000246896.3
ENST00000511674.1
HTN1
histatin 1
chr3_+_57882024 0.84 ENST00000494088.1
SLMAP
sarcolemma associated protein
chr19_+_20188830 0.83 ENST00000418063.2
ZNF90
zinc finger protein 90
chr14_+_22564294 0.83 ENST00000390452.2
TRDV1
T cell receptor delta variable 1
chr12_+_9980069 0.82 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr2_-_231084617 0.81 ENST00000409815.2
SP110
SP110 nuclear body protein
chr1_-_168464875 0.80 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr8_-_109260897 0.75 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
EIF3E
eukaryotic translation initiation factor 3, subunit E
chrX_-_11129229 0.75 ENST00000608176.1
ENST00000433747.2
ENST00000608576.1
ENST00000608916.1
RP11-120D5.1
RP11-120D5.1
chr2_-_231084659 0.75 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110
SP110 nuclear body protein
chr2_-_235363231 0.74 ENST00000439798.1
AC097713.4
AC097713.4
chr4_-_159956333 0.73 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr12_+_48722763 0.73 ENST00000335017.1
H1FNT
H1 histone family, member N, testis-specific
chr20_-_56647116 0.73 ENST00000441277.2
ENST00000452842.1
RP13-379L11.1
RP13-379L11.1
chr2_+_162480845 0.72 ENST00000375514.5
ENST00000415876.2
SLC4A10
solute carrier family 4, sodium bicarbonate transporter, member 10
chr1_-_152332480 0.70 ENST00000388718.5
FLG2
filaggrin family member 2
chr11_-_132812987 0.70 ENST00000541867.1
OPCML
opioid binding protein/cell adhesion molecule-like
chr15_-_33180439 0.69 ENST00000559610.1
FMN1
formin 1
chr10_+_4828815 0.68 ENST00000533295.1
AKR1E2
aldo-keto reductase family 1, member E2
chr14_+_23002427 0.68 ENST00000390527.1
TRAJ10
T cell receptor alpha joining 10
chr2_+_74648848 0.68 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WDR54
WD repeat domain 54
chr1_+_244515930 0.67 ENST00000366537.1
ENST00000308105.4
C1orf100
chromosome 1 open reading frame 100
chr7_-_14880892 0.66 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
DGKB
diacylglycerol kinase, beta 90kDa
chr9_+_105757590 0.64 ENST00000374798.3
ENST00000487798.1
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr2_+_200472779 0.63 ENST00000427045.1
ENST00000419243.1
AC093590.1
AC093590.1
chr10_-_4285923 0.62 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr14_-_22005343 0.61 ENST00000327430.3
SALL2
spalt-like transcription factor 2
chrX_+_18725758 0.61 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr8_+_66955648 0.61 ENST00000522619.1
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr4_-_153332886 0.59 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr14_+_100532771 0.59 ENST00000557153.1
EVL
Enah/Vasp-like
chr16_+_24266874 0.59 ENST00000005284.3
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr18_+_32556892 0.59 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr4_+_69313145 0.57 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr13_+_24844979 0.57 ENST00000454083.1
SPATA13
spermatogenesis associated 13
chrY_+_15418467 0.57 ENST00000595988.1
AC010877.1
Uncharacterized protein
chr16_+_333152 0.56 ENST00000219406.6
ENST00000404312.1
ENST00000456379.1
PDIA2
protein disulfide isomerase family A, member 2
chr2_+_210517895 0.54 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr13_+_24844857 0.54 ENST00000409126.1
ENST00000343003.6
SPATA13
spermatogenesis associated 13
chr3_+_62936098 0.54 ENST00000475886.1
ENST00000465684.1
ENST00000465262.1
ENST00000468072.1
LINC00698
long intergenic non-protein coding RNA 698
chr7_-_5998714 0.52 ENST00000539903.1
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr2_-_238343455 0.52 ENST00000409910.1
AC112721.2
AC112721.2
chr19_+_42212526 0.52 ENST00000598976.1
ENST00000435837.2
ENST00000221992.6
ENST00000405816.1
CEA
CEACAM5
Uncharacterized protein
carcinoembryonic antigen-related cell adhesion molecule 5
chr5_+_180682720 0.52 ENST00000599439.1
AC008443.1
CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chr11_-_62323702 0.51 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr5_-_75008244 0.51 ENST00000510798.1
ENST00000446329.2
POC5
POC5 centriolar protein
chr9_-_139137648 0.51 ENST00000358701.5
QSOX2
quiescin Q6 sulfhydryl oxidase 2
chr4_+_48485341 0.51 ENST00000273861.4
SLC10A4
solute carrier family 10, member 4
chr5_+_179921344 0.51 ENST00000261951.4
CNOT6
CCR4-NOT transcription complex, subunit 6
chr3_+_33155444 0.50 ENST00000320954.6
CRTAP
cartilage associated protein
chr4_+_70894130 0.49 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr13_-_51101468 0.47 ENST00000428276.1
RP11-175B12.2
RP11-175B12.2
chr11_-_104827425 0.47 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr17_+_61086917 0.46 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr6_+_130339710 0.46 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chrX_-_11284095 0.46 ENST00000303025.6
ENST00000534860.1
ARHGAP6
Rho GTPase activating protein 6
chr11_-_108093329 0.45 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr8_-_37411648 0.44 ENST00000519738.1
RP11-150O12.1
RP11-150O12.1
chr7_-_65113280 0.44 ENST00000593865.1
AC104057.1
Protein LOC100996407
chr5_+_137722255 0.44 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr3_+_73110810 0.42 ENST00000533473.1
EBLN2
endogenous Bornavirus-like nucleoprotein 2
chr6_-_131291572 0.42 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr14_-_34420259 0.42 ENST00000250457.3
ENST00000547327.2
EGLN3
egl-9 family hypoxia-inducible factor 3
chr2_-_99279928 0.40 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr2_-_37501692 0.40 ENST00000443977.1
PRKD3
protein kinase D3
chr12_-_25348007 0.39 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr12_-_118796971 0.38 ENST00000542902.1
TAOK3
TAO kinase 3
chr19_+_42212501 0.37 ENST00000398599.4
CEACAM5
carcinoembryonic antigen-related cell adhesion molecule 5
chr13_+_33160553 0.36 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr13_+_24844819 0.36 ENST00000399949.2
SPATA13
spermatogenesis associated 13
chr9_-_28670283 0.35 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr8_-_93029865 0.35 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_28527152 0.35 ENST00000321830.5
AL353354.1
Uncharacterized protein
chr18_+_34124507 0.35 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr12_-_49245916 0.35 ENST00000552512.1
ENST00000551468.1
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr3_+_119187785 0.34 ENST00000295588.4
ENST00000476573.1
POGLUT1
protein O-glucosyltransferase 1
chr15_-_42565023 0.34 ENST00000566474.1
TMEM87A
transmembrane protein 87A
chr1_-_232651312 0.33 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr18_+_3247779 0.33 ENST00000578611.1
ENST00000583449.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr19_+_22235310 0.32 ENST00000600162.1
ZNF257
zinc finger protein 257
chr7_-_22234381 0.32 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr12_-_118796910 0.32 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr10_-_116286656 0.31 ENST00000428430.1
ENST00000369266.3
ENST00000392952.3
ABLIM1
actin binding LIM protein 1
chr10_-_90712520 0.31 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr2_+_29001711 0.31 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr13_+_78315528 0.30 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr13_+_19756173 0.30 ENST00000382988.2
RP11-408E5.4
RP11-408E5.4
chr7_+_101460882 0.30 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1
cut-like homeobox 1
chr5_+_68860949 0.30 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr17_+_48823975 0.29 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr14_+_22251210 0.29 ENST00000390429.3
TRAV7
T cell receptor alpha variable 7
chr1_+_87012922 0.29 ENST00000263723.5
CLCA4
chloride channel accessory 4
chr11_-_55371874 0.28 ENST00000302231.4
OR4C11
olfactory receptor, family 4, subfamily C, member 11
chr4_+_147096837 0.28 ENST00000296581.5
ENST00000502781.1
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr7_+_99717230 0.27 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr5_-_150473127 0.27 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr19_-_44384291 0.27 ENST00000324394.6
ZNF404
zinc finger protein 404
chr18_+_3466248 0.27 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr4_+_128554081 0.27 ENST00000335251.6
ENST00000296461.5
INTU
inturned planar cell polarity protein
chr18_+_29027696 0.27 ENST00000257189.4
DSG3
desmoglein 3
chr14_+_29299437 0.26 ENST00000550827.1
ENST00000548087.1
ENST00000551588.1
ENST00000550122.1
CTD-2384A14.1
CTD-2384A14.1
chr11_+_24518723 0.26 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
LUZP2
leucine zipper protein 2
chr20_+_31870927 0.26 ENST00000253354.1
BPIFB1
BPI fold containing family B, member 1
chr15_+_54793169 0.25 ENST00000559093.1
UNC13C
unc-13 homolog C (C. elegans)
chr7_-_15014398 0.25 ENST00000437998.1
DGKB
diacylglycerol kinase, beta 90kDa
chr21_-_43735446 0.25 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr8_+_92114060 0.24 ENST00000518304.1
LRRC69
leucine rich repeat containing 69
chr5_+_98109322 0.24 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr9_-_98268883 0.24 ENST00000551630.1
ENST00000548420.1
PTCH1
patched 1
chrX_-_19988382 0.23 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23
chromosome X open reading frame 23
chr12_-_118797475 0.23 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr13_+_77522632 0.22 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr1_-_75100539 0.22 ENST00000420661.2
C1orf173
chromosome 1 open reading frame 173
chr15_-_72563585 0.22 ENST00000287196.9
ENST00000260376.7
PARP6
poly (ADP-ribose) polymerase family, member 6
chr7_+_156433573 0.20 ENST00000311822.8
RNF32
ring finger protein 32
chr18_-_19994830 0.20 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr9_+_116207007 0.19 ENST00000374140.2
RGS3
regulator of G-protein signaling 3
chr3_+_98001732 0.18 ENST00000355273.2
OR5H2
olfactory receptor, family 5, subfamily H, member 2
chr8_-_82373809 0.18 ENST00000379071.2
FABP9
fatty acid binding protein 9, testis
chr16_+_23652773 0.18 ENST00000563998.1
ENST00000568589.1
ENST00000568272.1
DCTN5
dynactin 5 (p25)
chr12_+_6309517 0.18 ENST00000382519.4
ENST00000009180.4
CD9
CD9 molecule
chr17_+_17082842 0.18 ENST00000579361.1
MPRIP
myosin phosphatase Rho interacting protein
chr1_-_89591749 0.17 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr7_-_99716914 0.17 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr10_-_24770632 0.17 ENST00000596413.1
AL353583.1
AL353583.1
chr13_+_78315466 0.17 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0035700 astrocyte chemotaxis(GO:0035700) regulation of astrocyte chemotaxis(GO:2000458)
0.7 2.8 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.6 2.5 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.5 2.4 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.4 3.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 3.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.4 1.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.3 1.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.3 1.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3 1.8 GO:0008063 Toll signaling pathway(GO:0008063)
0.3 1.8 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.3 3.1 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 0.5 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.1 1.3 GO:0097338 response to clozapine(GO:0097338)
0.1 1.0 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.6 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.9 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 1.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.7 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 2.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.3 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.7 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 1.6 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 1.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.8 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 1.3 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.3 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 3.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.3 GO:0090131 mesenchyme migration(GO:0090131)
0.0 2.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.7 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.2 GO:0010157 response to chlorate(GO:0010157)
0.0 1.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 1.0 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 1.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 3.7 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.4 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 1.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.9 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.9 GO:0045730 respiratory burst(GO:0045730)
0.0 1.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.7 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.1 GO:0060754 regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.7 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.5 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 2.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.5 GO:0007049 cell cycle(GO:0007049)
0.0 0.8 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.2 0.6 GO:0033150 cytoskeletal calyx(GO:0033150)
0.2 1.7 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.2 1.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 5.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.7 GO:0097441 basilar dendrite(GO:0097441)
0.1 3.6 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.9 GO:0032010 phagolysosome(GO:0032010)
0.1 0.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 3.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 2.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.5 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.9 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.3 GO:0044305 calyx of Held(GO:0044305)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.0 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.6 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.7 GO:1990752 microtubule end(GO:1990752)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 3.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 1.0 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 0.7 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.2 2.2 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.9 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 3.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.5 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.2 GO:0001851 complement component C3b binding(GO:0001851)
0.1 1.2 GO:0089720 caspase binding(GO:0089720)
0.1 0.9 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 2.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.8 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.3 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 3.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 3.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.0 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 2.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.9 GO:0070330 aromatase activity(GO:0070330)
0.0 1.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 2.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 4.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.6 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 3.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 4.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 3.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 2.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.9 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 4.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha