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Illumina Body Map 2, young vs old

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Results for LHX8

Z-value: 0.24

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Transcription factors associated with LHX8

Gene Symbol Gene ID Gene Info
LHX8
ENSG00000162624.10 LIM homeobox 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX8hg19_v2_chr1_+_75594119_75594119-0.271.4e-01Click!

Activity profile of LHX8 motif

Sorted Z-values of LHX8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_54982420 2.32 ENST00000257905.8
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr1_+_145413268 2.27 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
HFE2
hemochromatosis type 2 (juvenile)
chr2_+_168043793 1.58 ENST00000409273.1
ENST00000409605.1
XIRP2
xin actin-binding repeat containing 2
chr10_+_69869237 1.42 ENST00000373675.3
MYPN
myopalladin
chr12_-_54982300 1.36 ENST00000547431.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr7_-_120498357 1.34 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr12_+_101988627 1.28 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr8_+_9009296 1.15 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr12_+_101988774 1.14 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr2_-_183291741 1.11 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chrX_-_21776281 0.96 ENST00000379494.3
SMPX
small muscle protein, X-linked
chrX_-_73051037 0.93 ENST00000445814.1
XIST
X inactive specific transcript (non-protein coding)
chr4_+_74275057 0.90 ENST00000511370.1
ALB
albumin
chr8_-_82608409 0.89 ENST00000518568.1
SLC10A5
solute carrier family 10, member 5
chr8_-_25902876 0.87 ENST00000520164.1
EBF2
early B-cell factor 2
chr4_-_100242549 0.86 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr5_+_140235469 0.84 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr8_-_82395461 0.84 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr19_-_4535233 0.84 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr2_+_234621551 0.83 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr8_+_19759228 0.82 ENST00000520959.1
LPL
lipoprotein lipase
chr7_-_137028534 0.80 ENST00000348225.2
PTN
pleiotrophin
chr2_-_225266802 0.79 ENST00000243806.2
FAM124B
family with sequence similarity 124B
chr21_+_39644305 0.79 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr4_+_166300084 0.76 ENST00000402744.4
CPE
carboxypeptidase E
chr7_-_137028498 0.74 ENST00000393083.2
PTN
pleiotrophin
chr19_-_58204128 0.72 ENST00000597520.1
AC004017.1
Uncharacterized protein
chr12_+_48516357 0.70 ENST00000549022.1
ENST00000547587.1
ENST00000312352.7
PFKM
phosphofructokinase, muscle
chr4_-_69111401 0.70 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr15_-_34880646 0.70 ENST00000543376.1
GOLGA8A
golgin A8 family, member A
chr6_-_123958141 0.69 ENST00000334268.4
TRDN
triadin
chr4_-_186734275 0.69 ENST00000456060.1
SORBS2
sorbin and SH3 domain containing 2
chrX_+_84258832 0.69 ENST00000373173.2
APOOL
apolipoprotein O-like
chr1_+_47603109 0.68 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
CYP4A22
cytochrome P450, family 4, subfamily A, polypeptide 22
chr1_-_217262933 0.67 ENST00000359162.2
ESRRG
estrogen-related receptor gamma
chr6_-_24489842 0.65 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr18_+_71815743 0.65 ENST00000169551.6
ENST00000580087.1
TIMM21
translocase of inner mitochondrial membrane 21 homolog (yeast)
chr10_+_24738355 0.64 ENST00000307544.6
KIAA1217
KIAA1217
chr11_-_117800080 0.63 ENST00000524993.1
ENST00000528626.1
ENST00000445164.2
ENST00000430170.2
ENST00000526090.1
TMPRSS13
transmembrane protease, serine 13
chrX_-_5644225 0.63 ENST00000422914.1
RP11-733O18.1
RP11-733O18.1
chr5_+_140593509 0.61 ENST00000341948.4
PCDHB13
protocadherin beta 13
chrX_+_70798261 0.61 ENST00000373696.3
ACRC
acidic repeat containing
chr13_+_24883703 0.61 ENST00000332018.4
C1QTNF9
C1q and tumor necrosis factor related protein 9
chr14_-_36990354 0.61 ENST00000518149.1
NKX2-1
NK2 homeobox 1
chr1_+_95616933 0.61 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr12_+_48516463 0.60 ENST00000546465.1
PFKM
phosphofructokinase, muscle
chr1_-_217262969 0.60 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr4_-_186733363 0.60 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr4_-_110723134 0.58 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr5_+_135170331 0.57 ENST00000425402.1
ENST00000274513.5
ENST00000420621.1
ENST00000433282.2
ENST00000412661.2
SLC25A48
solute carrier family 25, member 48
chr3_+_154798162 0.57 ENST00000360490.2
MME
membrane metallo-endopeptidase
chr1_+_70876926 0.56 ENST00000370938.3
ENST00000346806.2
CTH
cystathionase (cystathionine gamma-lyase)
chr4_+_155484103 0.56 ENST00000302068.4
FGB
fibrinogen beta chain
chr22_+_22516550 0.53 ENST00000390284.2
IGLV4-60
immunoglobulin lambda variable 4-60
chr8_+_101349823 0.53 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr6_+_153071925 0.53 ENST00000367244.3
ENST00000367243.3
VIP
vasoactive intestinal peptide
chr6_-_56507586 0.53 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
DST
dystonin
chr21_-_34863998 0.53 ENST00000402202.1
ENST00000381947.3
DNAJC28
DnaJ (Hsp40) homolog, subfamily C, member 28
chr18_-_11908272 0.52 ENST00000592977.1
ENST00000590501.1
ENST00000586844.1
MPPE1
metallophosphoesterase 1
chr2_+_201994208 0.52 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr2_+_102758210 0.51 ENST00000450319.1
IL1R1
interleukin 1 receptor, type I
chr4_-_110723335 0.51 ENST00000394634.2
CFI
complement factor I
chr4_-_110723194 0.50 ENST00000394635.3
CFI
complement factor I
chr9_-_70490107 0.49 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5
COBW domain containing 5
chr11_+_60048004 0.49 ENST00000532114.1
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr1_+_144989309 0.49 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr12_-_15038779 0.49 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr18_-_11908329 0.48 ENST00000344987.7
ENST00000588103.1
ENST00000588191.1
ENST00000317235.7
ENST00000309976.9
ENST00000588186.1
ENST00000589267.1
MPPE1
metallophosphoesterase 1
chr11_+_60048129 0.47 ENST00000355131.3
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr2_+_102758271 0.47 ENST00000428279.1
IL1R1
interleukin 1 receptor, type I
chr9_+_70856899 0.47 ENST00000377342.5
ENST00000478048.1
CBWD3
COBW domain containing 3
chr6_-_44400720 0.46 ENST00000595057.1
AL133262.1
AL133262.1
chr7_+_151791095 0.46 ENST00000422997.2
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr10_+_81892347 0.45 ENST00000372267.2
PLAC9
placenta-specific 9
chr9_-_13165457 0.45 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr1_+_53662101 0.45 ENST00000371486.3
CPT2
carnitine palmitoyltransferase 2
chr6_+_143759575 0.45 ENST00000595616.1
AL031320.1
AL031320.1
chr9_-_69262509 0.45 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
CBWD6
COBW domain containing 6
chr1_+_230138476 0.45 ENST00000445339.1
RP11-552D4.1
RP11-552D4.1
chr21_-_16254231 0.44 ENST00000412426.1
ENST00000418954.1
AF127936.7
AF127936.7
chr2_+_114195268 0.44 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
CBWD2
COBW domain containing 2
chr6_-_123958111 0.44 ENST00000542443.1
TRDN
triadin
chr19_+_12175504 0.43 ENST00000439326.3
ZNF844
zinc finger protein 844
chr8_-_62602327 0.43 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr14_+_57046500 0.43 ENST00000261556.6
TMEM260
transmembrane protein 260
chr2_+_201994042 0.43 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr8_-_30013748 0.43 ENST00000607315.1
RP11-51J9.5
RP11-51J9.5
chr1_-_212004090 0.43 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr17_+_58018269 0.43 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr7_+_114055052 0.42 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr12_-_14967095 0.42 ENST00000316048.2
SMCO3
single-pass membrane protein with coiled-coil domains 3
chr2_-_152830441 0.42 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr1_-_168464875 0.42 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr9_-_179018 0.41 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
CBWD1
COBW domain containing 1
chr12_+_59989918 0.41 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr2_+_108145913 0.41 ENST00000443205.1
AC096669.3
AC096669.3
chr2_-_14541060 0.41 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr9_+_70856397 0.41 ENST00000360171.6
CBWD3
COBW domain containing 3
chr22_+_23487513 0.40 ENST00000263116.2
ENST00000341989.4
RAB36
RAB36, member RAS oncogene family
chr16_-_20338748 0.40 ENST00000575582.1
ENST00000341642.5
ENST00000381362.4
ENST00000572347.1
ENST00000572478.1
ENST00000302555.5
GP2
glycoprotein 2 (zymogen granule membrane)
chr9_-_20622478 0.40 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr9_-_5833027 0.40 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr3_+_195447738 0.40 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chrX_-_131262048 0.39 ENST00000298542.4
FRMD7
FERM domain containing 7
chr6_+_32006042 0.39 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr4_-_109684120 0.39 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ETNPPL
ethanolamine-phosphate phospho-lyase
chr14_+_57046530 0.39 ENST00000536419.1
ENST00000538838.1
TMEM260
transmembrane protein 260
chr4_+_155484155 0.38 ENST00000509493.1
FGB
fibrinogen beta chain
chr8_-_112039643 0.38 ENST00000524283.1
RP11-946L20.2
RP11-946L20.2
chr3_-_151102529 0.38 ENST00000302632.3
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr6_-_4347271 0.36 ENST00000437430.2
RP3-527G5.1
RP3-527G5.1
chr7_+_141408153 0.36 ENST00000397541.2
WEE2
WEE1 homolog 2 (S. pombe)
chr3_+_173116225 0.36 ENST00000457714.1
NLGN1
neuroligin 1
chr6_+_26087646 0.35 ENST00000309234.6
HFE
hemochromatosis
chr2_-_152830479 0.35 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr6_+_26087509 0.35 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE
hemochromatosis
chr6_-_75828774 0.35 ENST00000493109.2
COL12A1
collagen, type XII, alpha 1
chr7_+_7811992 0.34 ENST00000406829.1
RPA3-AS1
RPA3 antisense RNA 1
chr7_+_151791074 0.33 ENST00000447796.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr6_+_76599809 0.33 ENST00000430435.1
MYO6
myosin VI
chr11_+_1049862 0.33 ENST00000534584.1
RP13-870H17.3
RP13-870H17.3
chr2_-_136678123 0.33 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr16_-_20339123 0.32 ENST00000381360.5
GP2
glycoprotein 2 (zymogen granule membrane)
chr11_-_115127611 0.32 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr11_+_72975524 0.32 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr16_+_22217577 0.31 ENST00000263026.5
EEF2K
eukaryotic elongation factor-2 kinase
chr20_+_56964169 0.31 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr15_+_86805875 0.31 ENST00000389298.3
AGBL1
ATP/GTP binding protein-like 1
chr15_+_65843130 0.30 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr2_-_225266711 0.30 ENST00000389874.3
FAM124B
family with sequence similarity 124B
chr7_-_92777606 0.30 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr8_-_141810634 0.30 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr10_+_75668916 0.30 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr12_-_88974236 0.29 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr2_-_225266743 0.28 ENST00000409685.3
FAM124B
family with sequence similarity 124B
chrX_+_73164167 0.28 ENST00000414209.1
ENST00000602895.1
ENST00000453317.1
ENST00000602546.1
ENST00000602985.1
ENST00000415215.1
JPX
JPX transcript, XIST activator (non-protein coding)
chr8_+_17354617 0.28 ENST00000470360.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr6_-_152623231 0.27 ENST00000540663.1
ENST00000537033.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr9_+_108424738 0.27 ENST00000334077.3
TAL2
T-cell acute lymphocytic leukemia 2
chr19_+_34856078 0.27 ENST00000589399.1
ENST00000589640.1
ENST00000591204.1
GPI
glucose-6-phosphate isomerase
chr12_-_10766184 0.27 ENST00000539554.1
ENST00000381881.2
ENST00000320756.2
MAGOHB
mago-nashi homolog B (Drosophila)
chr10_-_110321541 0.27 ENST00000366253.2
RP11-163F15.1
RP11-163F15.1
chr5_-_41213607 0.27 ENST00000337836.5
ENST00000433294.1
C6
complement component 6
chr11_+_60048053 0.27 ENST00000337908.4
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr12_+_122326630 0.26 ENST00000541212.1
ENST00000340175.5
PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr7_+_30589829 0.26 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr14_+_50291993 0.26 ENST00000595378.1
AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr6_+_10633993 0.26 ENST00000417671.1
GCNT6
glucosaminyl (N-acetyl) transferase 6
chr13_-_24895566 0.26 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr15_+_54793169 0.26 ENST00000559093.1
UNC13C
unc-13 homolog C (C. elegans)
chr5_+_140165876 0.26 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr11_-_3400442 0.26 ENST00000429541.2
ENST00000532539.1
ZNF195
zinc finger protein 195
chr11_-_58035732 0.25 ENST00000395079.2
OR10W1
olfactory receptor, family 10, subfamily W, member 1
chr13_+_38923959 0.25 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1
ubiquitin-fold modifier 1
chr8_+_39806685 0.25 ENST00000389060.4
IDO2
indoleamine 2,3-dioxygenase 2
chrX_+_73164149 0.25 ENST00000602938.1
ENST00000602294.1
ENST00000602920.1
ENST00000602737.1
ENST00000602772.1
JPX
JPX transcript, XIST activator (non-protein coding)
chr12_-_39734783 0.25 ENST00000552961.1
KIF21A
kinesin family member 21A
chr1_+_66796401 0.25 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_-_150612089 0.25 ENST00000397891.3
FAM188B2
family with sequence similarity 188, member B2
chrX_-_23926004 0.25 ENST00000379226.4
ENST00000379220.3
APOO
apolipoprotein O
chr2_+_216946589 0.25 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169
transmembrane protein 169
chr1_-_95391315 0.25 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr11_+_72975578 0.25 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr3_-_47934234 0.24 ENST00000420772.2
MAP4
microtubule-associated protein 4
chr18_-_74839891 0.24 ENST00000581878.1
MBP
myelin basic protein
chr4_-_69083720 0.24 ENST00000432593.3
TMPRSS11BNL
TMPRSS11B N-terminal like
chr3_-_87842631 0.24 ENST00000462792.1
RP11-451B8.1
RP11-451B8.1
chr1_+_145883868 0.24 ENST00000447947.2
GPR89C
G protein-coupled receptor 89C
chr3_+_148545586 0.24 ENST00000282957.4
ENST00000468341.1
CPB1
carboxypeptidase B1 (tissue)
chr1_-_110933611 0.24 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr1_-_110933663 0.23 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr2_+_86947296 0.23 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr19_+_12175535 0.23 ENST00000550826.1
ZNF844
zinc finger protein 844
chr8_+_119294456 0.23 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr2_-_37068530 0.23 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr7_-_22234381 0.23 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr12_+_26348246 0.22 ENST00000422622.2
SSPN
sarcospan
chr2_+_234826016 0.22 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr19_+_42037433 0.22 ENST00000599316.1
ENST00000599770.1
AC006129.1
AC006129.1
chr6_+_43543942 0.22 ENST00000372226.1
ENST00000443535.1
POLH
polymerase (DNA directed), eta
chr7_-_20256965 0.22 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr7_+_151791037 0.21 ENST00000419245.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr5_+_140480083 0.21 ENST00000231130.2
PCDHB3
protocadherin beta 3
chr5_+_147715119 0.21 ENST00000377906.1
SPINK9
serine peptidase inhibitor, Kazal type 9
chr9_+_96846740 0.20 ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr19_+_34855925 0.20 ENST00000590375.1
ENST00000356487.5
GPI
glucose-6-phosphate isomerase
chr8_+_17354587 0.20 ENST00000494857.1
ENST00000522656.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr17_-_3301704 0.19 ENST00000322608.2
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr11_-_104817919 0.19 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr10_+_135207598 0.19 ENST00000477902.2
MTG1
mitochondrial ribosome-associated GTPase 1
chr19_+_34855874 0.19 ENST00000588991.2
GPI
glucose-6-phosphate isomerase
chr3_-_187455680 0.19 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr19_+_21688366 0.19 ENST00000358491.4
ENST00000597078.1
ZNF429
zinc finger protein 429
chr7_-_7575477 0.19 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr19_+_21264980 0.19 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714
zinc finger protein 714
chr11_+_72975559 0.19 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chrX_+_56258844 0.18 ENST00000374928.3
KLF8
Kruppel-like factor 8
chr1_-_146040968 0.17 ENST00000401010.3
NBPF11
neuroblastoma breakpoint family, member 11
chr1_-_247242048 0.17 ENST00000366503.2
ZNF670
zinc finger protein 670
chr5_-_150473127 0.17 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.3 0.9 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.3 1.1 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.3 0.8 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 0.7 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.2 1.3 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.2 0.5 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.2 0.8 GO:0070980 biphenyl catabolic process(GO:0070980)
0.2 1.0 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.2 0.6 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.2 0.5 GO:0034226 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.1 0.6 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.4 GO:0035038 female pronucleus assembly(GO:0035038)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 2.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.4 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.3 GO:0034059 response to anoxia(GO:0034059)
0.1 0.8 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.7 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.3 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 2.3 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.4 GO:0097115 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.9 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 1.0 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 1.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.6 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.6 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.4 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.6 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.4 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.7 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.8 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.9 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.5 GO:0070459 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) prolactin secretion(GO:0070459)
0.0 0.3 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.9 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 1.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 1.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 3.7 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 0.1 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.3 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0035587 purinergic receptor signaling pathway(GO:0035587) purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.9 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.4 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 1.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.0 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.3 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0043504 DNA replication, removal of RNA primer(GO:0043137) mitochondrial DNA repair(GO:0043504) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.5 GO:0001502 cartilage condensation(GO:0001502)
0.0 1.6 GO:0003281 ventricular septum development(GO:0003281)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0061015 snRNA import into nucleus(GO:0061015)
0.0 0.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.0 0.0 GO:1901963 glial cell fate determination(GO:0007403) oviduct development(GO:0060066) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793) positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.0 GO:1902304 phosphatidylserine exposure on blood platelet(GO:0097045) positive regulation of potassium ion export(GO:1902304)
0.0 0.0 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.6 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 1.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 1.0 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.9 GO:0061617 MICOS complex(GO:0061617)
0.1 0.3 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 1.1 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 2.4 GO:0032982 myosin filament(GO:0032982)
0.1 0.9 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.8 GO:0042627 chylomicron(GO:0042627)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0044305 calyx of Held(GO:0044305)
0.0 1.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.0 GO:0000793 chromosome, centromeric region(GO:0000775) condensed chromosome(GO:0000793)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 2.8 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.3 2.3 GO:0098821 BMP receptor activity(GO:0098821)
0.2 3.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 0.8 GO:0017129 triglyceride binding(GO:0017129)
0.2 1.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 1.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.4 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 1.0 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.7 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 1.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 0.8 GO:0035473 lipase binding(GO:0035473)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 3.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.4 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.9 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 1.0 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.9 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.7 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.7 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.8 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 1.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 1.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.4 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 2.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.4 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 2.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 2.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 2.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle