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Illumina Body Map 2, young vs old

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Results for MAFA

Z-value: 0.73

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Transcription factors associated with MAFA

Gene Symbol Gene ID Gene Info
MAFA
ENSG00000182759.3 MAF bZIP transcription factor A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFAhg19_v2_chr8_-_144512576_144512576-0.281.1e-01Click!

Activity profile of MAFA motif

Sorted Z-values of MAFA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_22730353 2.80 ENST00000390296.2
IGLV5-45
immunoglobulin lambda variable 5-45
chr22_+_22697537 2.57 ENST00000427632.2
IGLV9-49
immunoglobulin lambda variable 9-49
chr22_+_22764088 2.47 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr22_+_23063100 2.16 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr22_-_30662828 1.90 ENST00000403463.1
ENST00000215781.2
OSM
oncostatin M
chr12_-_22487588 1.74 ENST00000381424.3
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr16_+_28996572 1.71 ENST00000360872.5
ENST00000566177.1
ENST00000354453.4
LAT
linker for activation of T cells
chr16_+_28996364 1.61 ENST00000564277.1
LAT
linker for activation of T cells
chr9_-_130712995 1.57 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr1_+_200842083 1.56 ENST00000304244.2
GPR25
G protein-coupled receptor 25
chr1_+_156124162 1.55 ENST00000368282.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_+_174769006 1.52 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr22_+_23161491 1.47 ENST00000390316.2
IGLV3-9
immunoglobulin lambda variable 3-9 (gene/pseudogene)
chr21_+_44589118 1.43 ENST00000291554.2
CRYAA
crystallin, alpha A
chr12_-_22487618 1.39 ENST00000404299.3
ENST00000396037.4
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr13_-_30951282 1.37 ENST00000420219.1
LINC00426
long intergenic non-protein coding RNA 426
chr1_+_66458072 1.34 ENST00000423207.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr10_-_81708854 1.33 ENST00000372292.3
SFTPD
surfactant protein D
chr7_-_150754935 1.27 ENST00000297518.4
CDK5
cyclin-dependent kinase 5
chr22_+_23222886 1.27 ENST00000390319.2
IGLV3-1
immunoglobulin lambda variable 3-1
chrX_+_118892545 1.27 ENST00000343905.3
SOWAHD
sosondowah ankyrin repeat domain family member D
chr9_-_28670283 1.26 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr13_-_30951074 1.24 ENST00000416261.1
LINC00426
long intergenic non-protein coding RNA 426
chr11_-_62783303 1.17 ENST00000336232.2
ENST00000430500.2
SLC22A8
solute carrier family 22 (organic anion transporter), member 8
chr5_+_139739772 1.17 ENST00000506757.2
ENST00000230993.6
ENST00000506545.1
ENST00000432095.2
ENST00000507527.1
SLC4A9
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr1_+_90286562 1.14 ENST00000525774.1
ENST00000337338.5
LRRC8D
leucine rich repeat containing 8 family, member D
chr6_+_42896865 1.12 ENST00000372836.4
ENST00000394142.3
CNPY3
canopy FGF signaling regulator 3
chr19_-_48547294 1.10 ENST00000293255.2
CABP5
calcium binding protein 5
chr11_-_62783276 1.08 ENST00000535878.1
ENST00000545207.1
SLC22A8
solute carrier family 22 (organic anion transporter), member 8
chr7_-_86849883 1.04 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr12_+_79258444 1.03 ENST00000261205.4
SYT1
synaptotagmin I
chr4_+_74606223 1.02 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr5_+_176853702 1.02 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
GRK6
G protein-coupled receptor kinase 6
chr15_+_90744745 1.00 ENST00000558051.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr3_-_196439065 0.96 ENST00000399942.4
ENST00000409690.3
CEP19
centrosomal protein 19kDa
chr12_+_108525517 0.96 ENST00000332082.4
WSCD2
WSC domain containing 2
chr7_-_30029328 0.96 ENST00000425819.2
ENST00000409570.1
SCRN1
secernin 1
chr7_-_30029367 0.95 ENST00000242059.5
SCRN1
secernin 1
chr12_+_79258547 0.95 ENST00000457153.2
SYT1
synaptotagmin I
chr18_-_2982869 0.94 ENST00000584915.1
LPIN2
lipin 2
chr7_-_86849836 0.94 ENST00000455575.1
TMEM243
transmembrane protein 243, mitochondrial
chr16_-_89119355 0.93 ENST00000537498.1
CTD-2555A7.2
CTD-2555A7.2
chr7_-_30029574 0.89 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
SCRN1
secernin 1
chr6_-_74161977 0.89 ENST00000370318.1
ENST00000370315.3
MB21D1
Mab-21 domain containing 1
chr5_-_39270725 0.88 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr17_-_47925379 0.86 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4
tachykinin 4 (hemokinin)
chr3_-_131736593 0.84 ENST00000514999.1
CPNE4
copine IV
chr14_+_81421921 0.83 ENST00000554263.1
ENST00000554435.1
TSHR
thyroid stimulating hormone receptor
chr4_+_106067943 0.82 ENST00000380013.4
ENST00000394764.1
ENST00000413648.2
TET2
tet methylcytosine dioxygenase 2
chrX_-_107975917 0.77 ENST00000563887.1
RP6-24A23.6
Uncharacterized protein
chrX_-_92928557 0.77 ENST00000373079.3
ENST00000475430.2
NAP1L3
nucleosome assembly protein 1-like 3
chr6_-_99797522 0.76 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr2_+_191745535 0.75 ENST00000320717.3
GLS
glutaminase
chr17_-_3796334 0.75 ENST00000381771.2
ENST00000348335.2
ENST00000158166.5
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr2_+_115199876 0.66 ENST00000436732.1
ENST00000410059.1
DPP10
dipeptidyl-peptidase 10 (non-functional)
chrX_-_153141783 0.66 ENST00000458029.1
L1CAM
L1 cell adhesion molecule
chrX_-_153141302 0.65 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1CAM
L1 cell adhesion molecule
chr14_+_81421710 0.64 ENST00000342443.6
TSHR
thyroid stimulating hormone receptor
chr1_-_247615308 0.63 ENST00000318749.6
OR2B11
olfactory receptor, family 2, subfamily B, member 11
chr19_+_12949251 0.61 ENST00000251472.4
MAST1
microtubule associated serine/threonine kinase 1
chr17_-_76128488 0.61 ENST00000322914.3
TMC6
transmembrane channel-like 6
chr6_+_97372596 0.61 ENST00000369261.4
KLHL32
kelch-like family member 32
chr3_+_196439170 0.59 ENST00000392391.3
ENST00000314118.4
PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr9_+_33629119 0.59 ENST00000331828.4
TRBV21OR9-2
T cell receptor beta variable 21/OR9-2 (pseudogene)
chrX_-_106959631 0.59 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chr17_+_25936862 0.59 ENST00000582410.1
KSR1
kinase suppressor of ras 1
chr15_+_90744533 0.59 ENST00000411539.2
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr14_+_81421861 0.58 ENST00000298171.2
TSHR
thyroid stimulating hormone receptor
chr3_+_172361483 0.55 ENST00000598405.1
AC007919.2
HCG1787166; PRO1163; Uncharacterized protein
chr19_+_21541732 0.54 ENST00000311015.3
ZNF738
zinc finger protein 738
chrX_-_153141434 0.52 ENST00000407935.2
ENST00000439496.1
L1CAM
L1 cell adhesion molecule
chr14_+_81421355 0.52 ENST00000541158.2
TSHR
thyroid stimulating hormone receptor
chr2_+_191745560 0.51 ENST00000338435.4
GLS
glutaminase
chr15_-_23086394 0.51 ENST00000337435.4
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr7_-_73133959 0.50 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
STX1A
syntaxin 1A (brain)
chr11_-_104817919 0.50 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chrX_-_1511617 0.50 ENST00000381401.5
SLC25A6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr9_+_131549610 0.49 ENST00000223865.8
TBC1D13
TBC1 domain family, member 13
chr17_+_18759612 0.49 ENST00000432893.2
ENST00000414602.1
ENST00000574522.1
ENST00000570450.1
ENST00000419071.2
PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr2_+_102624977 0.49 ENST00000441002.1
IL1R2
interleukin 1 receptor, type II
chr6_+_97372645 0.48 ENST00000536676.1
ENST00000544166.1
KLHL32
kelch-like family member 32
chr1_+_202091980 0.48 ENST00000367282.5
GPR37L1
G protein-coupled receptor 37 like 1
chr2_-_26205550 0.47 ENST00000405914.1
KIF3C
kinesin family member 3C
chr20_-_30795511 0.45 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr15_-_23086259 0.45 ENST00000538684.1
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chrY_-_1461617 0.44 ENSTR0000381401.5
SLC25A6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr10_+_102505468 0.44 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
PAX2
paired box 2
chr10_+_102505954 0.43 ENST00000556085.1
ENST00000427256.1
PAX2
paired box 2
chr9_+_125133467 0.43 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr15_+_98503922 0.41 ENST00000268042.6
ARRDC4
arrestin domain containing 4
chr22_+_41075277 0.41 ENST00000381433.2
MCHR1
melanin-concentrating hormone receptor 1
chr6_+_97372734 0.40 ENST00000539200.1
KLHL32
kelch-like family member 32
chr1_-_54872059 0.40 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr3_+_196439275 0.40 ENST00000296333.5
PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr19_+_21541777 0.40 ENST00000380870.4
ENST00000597810.1
ENST00000594245.1
ZNF738
zinc finger protein 738
chr11_-_66103932 0.39 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chrX_-_53310791 0.38 ENST00000375365.2
IQSEC2
IQ motif and Sec7 domain 2
chr16_+_56225248 0.38 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr5_+_138629628 0.38 ENST00000508689.1
ENST00000514528.1
MATR3
matrin 3
chr3_+_52422899 0.37 ENST00000480649.1
DNAH1
dynein, axonemal, heavy chain 1
chr22_+_22599075 0.37 ENST00000403807.3
VPREB1
pre-B lymphocyte 1
chr4_+_72052964 0.36 ENST00000264485.5
ENST00000425175.1
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr7_-_108168580 0.36 ENST00000453085.1
PNPLA8
patatin-like phospholipase domain containing 8
chr17_+_41363854 0.36 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr16_-_67514982 0.35 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chrX_-_65859096 0.35 ENST00000456230.2
EDA2R
ectodysplasin A2 receptor
chr12_+_120137573 0.35 ENST00000535109.1
RP1-127H14.3
Uncharacterized protein
chr7_+_142749417 0.35 ENST00000418316.1
OR6V1
olfactory receptor, family 6, subfamily V, member 1
chr15_-_66858298 0.35 ENST00000537670.1
LCTL
lactase-like
chr1_-_153517473 0.34 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr17_-_17109579 0.33 ENST00000321560.3
PLD6
phospholipase D family, member 6
chr1_-_216978709 0.33 ENST00000360012.3
ESRRG
estrogen-related receptor gamma
chr16_-_21436459 0.32 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr5_+_138629389 0.32 ENST00000504045.1
ENST00000504311.1
ENST00000502499.1
MATR3
matrin 3
chr12_-_2027639 0.31 ENST00000586184.1
ENST00000587995.1
ENST00000585732.1
CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr11_-_66103867 0.31 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr14_-_36983034 0.30 ENST00000518529.2
SFTA3
surfactant associated 3
chr17_-_10325261 0.30 ENST00000403437.2
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chrX_+_74493896 0.30 ENST00000373383.4
ENST00000373379.1
UPRT
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr6_+_147525541 0.29 ENST00000367481.3
ENST00000546097.1
STXBP5
syntaxin binding protein 5 (tomosyn)
chrX_-_47509887 0.29 ENST00000247161.3
ENST00000592066.1
ENST00000376983.3
ELK1
ELK1, member of ETS oncogene family
chr11_+_118826999 0.29 ENST00000264031.2
UPK2
uroplakin 2
chr5_+_138629417 0.29 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
MATR3
matrin 3
chr6_+_89791507 0.28 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr6_+_147525661 0.28 ENST00000321680.6
ENST00000367480.3
STXBP5
syntaxin binding protein 5 (tomosyn)
chr10_+_135122906 0.28 ENST00000368554.4
ZNF511
zinc finger protein 511
chr19_-_37958318 0.28 ENST00000316950.6
ENST00000591710.1
ZNF569
zinc finger protein 569
chr3_-_48754599 0.28 ENST00000413654.1
ENST00000454335.1
ENST00000440424.1
ENST00000449610.1
ENST00000443964.1
ENST00000417896.1
ENST00000413298.1
ENST00000449563.1
ENST00000443853.1
ENST00000437427.1
ENST00000446860.1
ENST00000412850.1
ENST00000424035.1
ENST00000340879.4
ENST00000431721.2
ENST00000434860.1
ENST00000328631.5
ENST00000432678.2
IP6K2
inositol hexakisphosphate kinase 2
chr3_-_49823941 0.28 ENST00000321599.4
ENST00000395238.1
ENST00000468463.1
ENST00000460540.1
IP6K1
inositol hexakisphosphate kinase 1
chr5_+_138629337 0.27 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
MATR3
matrin 3
chr8_+_85095497 0.27 ENST00000522455.1
ENST00000521695.1
RALYL
RALY RNA binding protein-like
chr11_-_777467 0.27 ENST00000397472.2
ENST00000524550.1
ENST00000319863.8
ENST00000526325.1
ENST00000442059.2
PDDC1
Parkinson disease 7 domain containing 1
chr8_+_85095769 0.26 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chr16_+_22524844 0.25 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr1_+_206858328 0.24 ENST00000367103.3
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr16_-_46865047 0.24 ENST00000394806.2
C16orf87
chromosome 16 open reading frame 87
chr5_-_22853429 0.24 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chrX_-_47509994 0.23 ENST00000343894.4
ELK1
ELK1, member of ETS oncogene family
chr15_+_80696666 0.23 ENST00000303329.4
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr5_+_60933634 0.23 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr22_+_22599189 0.22 ENST00000302273.2
VPREB1
pre-B lymphocyte 1
chr7_-_135412925 0.22 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr3_+_107241783 0.22 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)
chr6_+_22221010 0.22 ENST00000567753.1
RP11-524C21.2
RP11-524C21.2
chr10_-_70231639 0.20 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
DNA2
DNA replication helicase/nuclease 2
chr1_-_45956822 0.20 ENST00000372086.3
ENST00000341771.6
TESK2
testis-specific kinase 2
chr1_-_32403370 0.20 ENST00000534796.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr16_-_29415350 0.20 ENST00000524087.1
NPIPB11
nuclear pore complex interacting protein family, member B11
chr16_+_70258261 0.19 ENST00000594734.1
FKSG63
FKSG63
chrX_+_3189861 0.19 ENST00000457435.1
ENST00000420429.2
CXorf28
chromosome X open reading frame 28
chr7_-_151433342 0.19 ENST00000433631.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr16_-_21868739 0.18 ENST00000415645.2
NPIPB4
nuclear pore complex interacting protein family, member B4
chr4_+_2470664 0.18 ENST00000314289.8
ENST00000541204.1
ENST00000502316.1
ENST00000507247.1
ENST00000509258.1
ENST00000511859.1
RNF4
ring finger protein 4
chr9_-_127905736 0.18 ENST00000336505.6
ENST00000373549.4
SCAI
suppressor of cancer cell invasion
chr16_-_29517141 0.18 ENST00000550665.1
RP11-231C14.4
Uncharacterized protein
chr11_+_33563618 0.17 ENST00000526400.1
KIAA1549L
KIAA1549-like
chr3_+_131100515 0.17 ENST00000537561.1
ENST00000359850.3
ENST00000521288.1
ENST00000502852.1
NUDT16
nudix (nucleoside diphosphate linked moiety X)-type motif 16
chr4_-_151936416 0.17 ENST00000510413.1
ENST00000507224.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr10_-_118897567 0.16 ENST00000369206.5
VAX1
ventral anterior homeobox 1
chr1_-_45956800 0.16 ENST00000538496.1
TESK2
testis-specific kinase 2
chr9_-_125148928 0.15 ENST00000600713.1
AL162424.1
Uncharacterized protein
chr1_-_13331692 0.15 ENST00000353410.5
ENST00000376173.3
PRAMEF3
PRAME family member 3
chr13_+_28194873 0.15 ENST00000302979.3
POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr5_-_114505624 0.15 ENST00000513154.1
TRIM36
tripartite motif containing 36
chr4_+_72053017 0.15 ENST00000351898.6
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr14_+_24605389 0.14 ENST00000382708.3
ENST00000561435.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr19_+_36103631 0.14 ENST00000203166.5
ENST00000379045.2
HAUS5
HAUS augmin-like complex, subunit 5
chr9_-_130889990 0.13 ENST00000449878.1
PTGES2
prostaglandin E synthase 2
chr6_+_116692102 0.13 ENST00000359564.2
DSE
dermatan sulfate epimerase
chr17_+_38465441 0.13 ENST00000577646.1
ENST00000254066.5
RARA
retinoic acid receptor, alpha
chr4_-_10118348 0.13 ENST00000502702.1
WDR1
WD repeat domain 1
chr21_+_41239243 0.12 ENST00000328619.5
PCP4
Purkinje cell protein 4
chr12_+_21654714 0.12 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr3_+_141121164 0.12 ENST00000510338.1
ENST00000504673.1
ZBTB38
zinc finger and BTB domain containing 38
chr4_-_151936865 0.11 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr6_+_31021973 0.10 ENST00000570223.1
ENST00000566475.1
ENST00000426185.1
HCG22
HLA complex group 22
chr20_+_306221 0.09 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr11_+_107461948 0.09 ENST00000265840.7
ENST00000443271.2
ELMOD1
ELMO/CED-12 domain containing 1
chr20_+_306177 0.08 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr8_-_114389353 0.08 ENST00000343508.3
CSMD3
CUB and Sushi multiple domains 3
chr4_+_6784401 0.08 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr2_+_118846008 0.07 ENST00000245787.4
INSIG2
insulin induced gene 2
chr10_-_118897806 0.07 ENST00000277905.2
VAX1
ventral anterior homeobox 1
chr5_+_179286013 0.07 ENST00000499601.2
CTC-241N9.1
Uncharacterized protein
chr8_+_85095553 0.06 ENST00000521268.1
RALYL
RALY RNA binding protein-like
chr11_+_33563821 0.05 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr19_+_33182823 0.05 ENST00000397061.3
NUDT19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr11_+_72929319 0.03 ENST00000393597.2
ENST00000311131.2
P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr5_-_94620239 0.03 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr2_-_30143525 0.03 ENST00000431873.1
ALK
anaplastic lymphoma receptor tyrosine kinase
chr8_+_145438870 0.03 ENST00000527931.1
FAM203B
family with sequence similarity 203, member B
chr10_-_49701686 0.02 ENST00000417247.2
ARHGAP22
Rho GTPase activating protein 22
chr5_-_179285848 0.02 ENST00000403396.2
ENST00000292586.6
C5orf45
chromosome 5 open reading frame 45
chr19_+_54641444 0.02 ENST00000221232.5
ENST00000358389.3
CNOT3
CCR4-NOT transcription complex, subunit 3
chr1_+_163039143 0.02 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
RGS4
regulator of G-protein signaling 4
chr5_-_179285785 0.00 ENST00000520698.1
ENST00000518235.1
ENST00000376931.2
ENST00000518219.1
ENST00000521333.1
ENST00000523084.1
C5orf45
chromosome 5 open reading frame 45
chr16_-_79015739 0.00 ENST00000594986.1
PIH1
HCG1979943; Uncharacterized protein
chr10_-_79397479 0.00 ENST00000404771.3
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr14_+_50779071 0.00 ENST00000426751.2
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:1905229 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.3 2.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.3 0.9 GO:0052255 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.3 0.9 GO:0035566 regulation of metanephros size(GO:0035566)
0.2 1.9 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 1.3 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2 2.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.4 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.5 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.9 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.5 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 1.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.3 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.1 0.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 3.1 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 1.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.2 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.1 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.5 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 2.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 3.3 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.8 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.9 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 1.0 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 5.9 GO:0030449 regulation of complement activation(GO:0030449)
0.0 3.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 7.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.5 GO:0034378 chylomicron assembly(GO:0034378)
0.0 1.4 GO:0042026 protein refolding(GO:0042026)
0.0 0.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 1.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 1.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 2.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 1.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 2.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.5 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 3.3 GO:0042629 mast cell granule(GO:0042629)
0.1 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.9 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 1.6 GO:0042599 lamellar body(GO:0042599)
0.0 1.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.9 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0097542 ciliary tip(GO:0097542)
0.0 5.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.3 3.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 0.9 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.2 0.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 0.6 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 2.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 1.3 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.6 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 1.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 3.1 GO:0038191 neuropilin binding(GO:0038191)
0.1 3.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 2.8 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 0.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 1.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 11.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 1.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.4 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 3.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.9 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 4.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 2.5 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 1.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 2.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 4.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 2.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.7 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.9 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE