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Illumina Body Map 2, young vs old

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Results for MAFF_MAFG

Z-value: 0.39

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Transcription factors associated with MAFF_MAFG

Gene Symbol Gene ID Gene Info
MAFF
ENSG00000185022.7 MAF bZIP transcription factor F
MAFG
ENSG00000197063.6 MAF bZIP transcription factor G

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFGhg19_v2_chr17_-_79881408_79881423-0.232.1e-01Click!
MAFFhg19_v2_chr22_+_38609538_386095470.086.5e-01Click!

Activity profile of MAFF_MAFG motif

Sorted Z-values of MAFF_MAFG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrY_+_2709527 6.29 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr22_+_21133469 3.51 ENST00000406799.1
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr12_+_20968608 2.55 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chrY_+_2709906 2.48 ENST00000430575.1
RPS4Y1
ribosomal protein S4, Y-linked 1
chr3_+_186383741 2.25 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr11_+_75428857 2.12 ENST00000198801.5
MOGAT2
monoacylglycerol O-acyltransferase 2
chr2_+_211421262 1.92 ENST00000233072.5
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chrX_+_138612889 1.64 ENST00000218099.2
ENST00000394090.2
F9
coagulation factor IX
chr1_+_196912902 1.55 ENST00000476712.2
ENST00000367415.5
CFHR2
complement factor H-related 2
chr2_+_128177253 1.50 ENST00000427769.1
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr18_+_56113488 1.45 ENST00000590797.1
RP11-1151B14.3
RP11-1151B14.3
chr3_+_119499331 1.39 ENST00000393716.2
ENST00000466380.1
NR1I2
nuclear receptor subfamily 1, group I, member 2
chr1_+_22979474 1.35 ENST00000509305.1
C1QB
complement component 1, q subcomponent, B chain
chr1_+_22979676 1.34 ENST00000432749.2
ENST00000314933.6
C1QB
complement component 1, q subcomponent, B chain
chr10_+_116853091 1.25 ENST00000526946.1
ATRNL1
attractin-like 1
chr9_-_34710066 1.25 ENST00000378792.1
ENST00000259607.2
CCL21
chemokine (C-C motif) ligand 21
chr2_+_115219171 1.24 ENST00000409163.1
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr1_-_62785054 1.24 ENST00000371153.4
KANK4
KN motif and ankyrin repeat domains 4
chr22_+_23010756 1.18 ENST00000390304.2
IGLV3-27
immunoglobulin lambda variable 3-27
chr1_-_62784935 1.17 ENST00000354381.3
KANK4
KN motif and ankyrin repeat domains 4
chr12_+_101988774 1.17 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr5_-_54468974 1.17 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B
cell division cycle 20B
chr11_+_124789146 1.12 ENST00000408930.5
HEPN1
hepatocellular carcinoma, down-regulated 1
chr12_+_103981044 1.11 ENST00000388887.2
STAB2
stabilin 2
chr16_-_4838255 1.11 ENST00000591624.1
ENST00000396693.5
SEPT12
septin 12
chr4_+_74275057 1.10 ENST00000511370.1
ALB
albumin
chr19_-_14168391 1.09 ENST00000589048.1
PALM3
paralemmin 3
chr12_+_56075330 1.08 ENST00000394252.3
METTL7B
methyltransferase like 7B
chr1_-_157567868 1.07 ENST00000271532.1
FCRL4
Fc receptor-like 4
chr4_+_156775910 1.03 ENST00000506072.1
ENST00000507590.1
TDO2
tryptophan 2,3-dioxygenase
chr16_+_82068830 1.02 ENST00000199936.4
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr16_+_82068585 1.01 ENST00000563491.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr10_+_124030819 1.00 ENST00000260723.4
ENST00000368994.2
BTBD16
BTB (POZ) domain containing 16
chr1_+_119911425 0.99 ENST00000361035.4
ENST00000325945.3
HAO2
hydroxyacid oxidase 2 (long chain)
chr4_+_74347400 0.96 ENST00000226355.3
AFM
afamin
chr5_-_115152651 0.94 ENST00000250535.4
CDO1
cysteine dioxygenase type 1
chr12_+_101988627 0.94 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr1_+_110254850 0.93 ENST00000369812.5
ENST00000256593.3
ENST00000369813.1
GSTM5
glutathione S-transferase mu 5
chr6_+_159291090 0.93 ENST00000367073.4
ENST00000608817.1
C6orf99
chromosome 6 open reading frame 99
chr1_+_119911396 0.89 ENST00000457318.1
HAO2
hydroxyacid oxidase 2 (long chain)
chr14_+_94640671 0.88 ENST00000328839.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr16_+_56716336 0.87 ENST00000394485.4
ENST00000562939.1
MT1X
metallothionein 1X
chr16_+_82068873 0.87 ENST00000566213.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr1_+_85527987 0.86 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr12_-_47219733 0.86 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
SLC38A4
solute carrier family 38, member 4
chr1_+_196788887 0.84 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr7_+_100551239 0.84 ENST00000319509.7
MUC3A
mucin 3A, cell surface associated
chr11_-_5248294 0.81 ENST00000335295.4
HBB
hemoglobin, beta
chr5_-_42811986 0.81 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr7_+_302918 0.80 ENST00000599994.1
AC187652.1
Protein LOC100996433
chr5_-_42812143 0.79 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr16_-_87970122 0.79 ENST00000309893.2
CA5A
carbonic anhydrase VA, mitochondrial
chr16_-_56701933 0.78 ENST00000568675.1
ENST00000569500.1
ENST00000444837.2
ENST00000379811.3
MT1G
metallothionein 1G
chr14_+_94640633 0.77 ENST00000304338.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr2_-_169887827 0.77 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr4_-_187517928 0.77 ENST00000512772.1
FAT1
FAT atypical cadherin 1
chrX_-_52827141 0.76 ENST00000375511.3
SPANXN5
SPANX family, member N5
chr5_-_101834617 0.75 ENST00000513675.1
ENST00000379807.3
SLCO6A1
solute carrier organic anion transporter family, member 6A1
chrX_+_153813407 0.74 ENST00000443287.2
ENST00000333128.3
CTAG1A
cancer/testis antigen 1A
chr5_-_101834712 0.74 ENST00000506729.1
ENST00000389019.3
ENST00000379810.1
SLCO6A1
solute carrier organic anion transporter family, member 6A1
chr7_-_14026123 0.73 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr6_-_25930904 0.73 ENST00000377850.3
SLC17A2
solute carrier family 17, member 2
chr11_-_914774 0.72 ENST00000528154.1
ENST00000525840.1
CHID1
chitinase domain containing 1
chr22_-_27014043 0.72 ENST00000215939.2
CRYBB1
crystallin, beta B1
chr17_-_14140166 0.71 ENST00000420162.2
ENST00000431716.2
CDRT15
CMT1A duplicated region transcript 15
chr6_+_160542870 0.71 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr5_+_176057663 0.71 ENST00000318682.6
EIF4E1B
eukaryotic translation initiation factor 4E family member 1B
chr2_-_26864228 0.70 ENST00000288861.4
CIB4
calcium and integrin binding family member 4
chr10_-_48416849 0.70 ENST00000249598.1
GDF2
growth differentiation factor 2
chr17_-_34313685 0.70 ENST00000435911.2
ENST00000586216.1
ENST00000394509.4
CCL14
chemokine (C-C motif) ligand 14
chr10_-_7513904 0.67 ENST00000420395.1
RP5-1031D4.2
RP5-1031D4.2
chr6_-_43478239 0.67 ENST00000372441.1
LRRC73
leucine rich repeat containing 73
chr1_+_57320437 0.66 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr5_-_176057518 0.65 ENST00000393693.2
SNCB
synuclein, beta
chr12_+_24376201 0.65 ENST00000540733.1
ENST00000539583.1
RP11-778H2.1
RP11-778H2.1
chr10_+_5005445 0.64 ENST00000380872.4
AKR1C1
aldo-keto reductase family 1, member C1
chr14_+_32798547 0.63 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr16_+_31539183 0.63 ENST00000302312.4
AHSP
alpha hemoglobin stabilizing protein
chrX_-_5644225 0.63 ENST00000422914.1
RP11-733O18.1
RP11-733O18.1
chr22_+_22556057 0.63 ENST00000390286.2
IGLV11-55
immunoglobulin lambda variable 11-55 (non-functional)
chr9_-_13432977 0.62 ENST00000605459.1
RP11-536O18.2
RP11-536O18.2
chr16_+_31539197 0.62 ENST00000564707.1
AHSP
alpha hemoglobin stabilizing protein
chr5_-_176057365 0.62 ENST00000310112.3
SNCB
synuclein, beta
chrX_+_30260054 0.61 ENST00000378982.2
MAGEB4
melanoma antigen family B, 4
chrX_+_69501943 0.60 ENST00000509895.1
ENST00000374473.2
ENST00000276066.4
RAB41
RAB41, member RAS oncogene family
chr12_-_22094336 0.60 ENST00000326684.4
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chrX_-_20134990 0.60 ENST00000379651.3
ENST00000443379.3
ENST00000379643.5
MAP7D2
MAP7 domain containing 2
chr7_-_22234381 0.60 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chrX_+_140096761 0.59 ENST00000370530.1
SPANXB1
SPANX family, member B1
chr22_+_44319648 0.59 ENST00000423180.2
PNPLA3
patatin-like phospholipase domain containing 3
chr6_+_131894284 0.59 ENST00000368087.3
ENST00000356962.2
ARG1
arginase 1
chr19_-_40896081 0.59 ENST00000291823.2
HIPK4
homeodomain interacting protein kinase 4
chr17_+_53343171 0.58 ENST00000430986.2
HLF
hepatic leukemia factor
chr12_-_127544894 0.58 ENST00000546062.1
ENST00000512624.2
ENST00000540244.1
RP11-575F12.1
RP11-575F12.1
chr19_-_36297348 0.57 ENST00000589835.1
PRODH2
proline dehydrogenase (oxidase) 2
chr2_-_219858123 0.57 ENST00000453769.1
ENST00000295728.2
ENST00000392096.2
CRYBA2
crystallin, beta A2
chr11_-_114271139 0.56 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr10_-_73497581 0.56 ENST00000398786.2
C10orf105
chromosome 10 open reading frame 105
chr17_+_53343577 0.56 ENST00000573945.1
HLF
hepatic leukemia factor
chr4_+_147560042 0.55 ENST00000281321.3
POU4F2
POU class 4 homeobox 2
chr3_-_142720267 0.55 ENST00000597953.1
RP11-91G21.1
RP11-91G21.1
chr14_+_94577074 0.55 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr13_-_44453826 0.55 ENST00000444614.3
CCDC122
coiled-coil domain containing 122
chr2_-_187713891 0.55 ENST00000295131.2
ZSWIM2
zinc finger, SWIM-type containing 2
chr1_-_67600639 0.54 ENST00000544837.1
ENST00000603691.1
C1orf141
chromosome 1 open reading frame 141
chr9_-_113100088 0.54 ENST00000374510.4
ENST00000423740.2
ENST00000374511.3
ENST00000374507.4
TXNDC8
thioredoxin domain containing 8 (spermatozoa)
chr18_-_40695604 0.54 ENST00000590910.1
ENST00000326695.5
ENST00000589109.1
ENST00000282028.4
RIT2
Ras-like without CAAX 2
chr16_+_76343743 0.53 ENST00000478060.1
CNTNAP4
contactin associated protein-like 4
chr6_+_160542821 0.53 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr10_+_4448667 0.53 ENST00000434902.1
LINC00703
long intergenic non-protein coding RNA 703
chr22_-_44708731 0.52 ENST00000381176.4
KIAA1644
KIAA1644
chr7_-_14029515 0.52 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr17_+_30771279 0.52 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr1_-_109655355 0.52 ENST00000369945.3
C1orf194
chromosome 1 open reading frame 194
chr7_-_14026063 0.51 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr2_-_166930131 0.51 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr1_-_109655377 0.50 ENST00000369948.3
C1orf194
chromosome 1 open reading frame 194
chr10_-_13544945 0.50 ENST00000378605.3
ENST00000341083.3
BEND7
BEN domain containing 7
chrX_-_139866723 0.50 ENST00000370532.2
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr9_-_138391692 0.50 ENST00000429260.2
C9orf116
chromosome 9 open reading frame 116
chr11_+_58695174 0.49 ENST00000317391.4
GLYATL1
glycine-N-acyltransferase-like 1
chr4_-_170924888 0.49 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr10_-_45496336 0.49 ENST00000298298.1
C10orf25
chromosome 10 open reading frame 25
chr1_+_154966058 0.48 ENST00000392487.1
LENEP
lens epithelial protein
chr12_-_22094159 0.48 ENST00000538350.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_+_145549203 0.48 ENST00000355594.4
ENST00000544626.1
ANKRD35
ankyrin repeat domain 35
chr10_+_124320156 0.48 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1
deleted in malignant brain tumors 1
chr8_+_39972170 0.48 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr12_-_71533055 0.48 ENST00000552128.1
TSPAN8
tetraspanin 8
chr18_+_71983048 0.47 ENST00000579455.1
C18orf63
chromosome 18 open reading frame 63
chr6_-_113953705 0.47 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr9_-_34376851 0.47 ENST00000297625.7
KIAA1161
KIAA1161
chr2_+_171640291 0.47 ENST00000409885.1
ERICH2
glutamate-rich 2
chr10_+_122216316 0.46 ENST00000398250.1
ENST00000439221.1
ENST00000398248.1
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr2_+_182850743 0.46 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr1_+_2005126 0.46 ENST00000495347.1
PRKCZ
protein kinase C, zeta
chr17_+_20483037 0.46 ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15-like 2
chr7_-_122526799 0.46 ENST00000334010.7
ENST00000313070.7
CADPS2
Ca++-dependent secretion activator 2
chr1_-_169733789 0.46 ENST00000454271.1
ENST00000609271.1
RP1-117P20.3
SELE
RP1-117P20.3
selectin E
chr11_-_108338218 0.45 ENST00000525729.1
ENST00000393084.1
C11orf65
chromosome 11 open reading frame 65
chr19_-_33555780 0.45 ENST00000254260.3
ENST00000400226.4
RHPN2
rhophilin, Rho GTPase binding protein 2
chr8_-_121825088 0.45 ENST00000520717.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr3_+_153839149 0.45 ENST00000465093.1
ENST00000465817.1
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr11_-_10590238 0.45 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr8_+_20811140 0.45 ENST00000523035.1
RP11-369E15.4
RP11-369E15.4
chr10_+_24498060 0.45 ENST00000376454.3
ENST00000376452.3
KIAA1217
KIAA1217
chr5_+_89854595 0.45 ENST00000405460.2
GPR98
G protein-coupled receptor 98
chr6_+_132455526 0.44 ENST00000443303.1
LINC01013
long intergenic non-protein coding RNA 1013
chrX_+_3189861 0.44 ENST00000457435.1
ENST00000420429.2
CXorf28
chromosome X open reading frame 28
chr5_+_167181917 0.44 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr17_-_57604227 0.43 ENST00000584262.1
RP11-567L7.6
RP11-567L7.6
chr22_+_21987005 0.43 ENST00000607942.1
ENST00000425975.1
ENST00000292779.3
CCDC116
coiled-coil domain containing 116
chr7_+_1084206 0.42 ENST00000444847.1
GPR146
G protein-coupled receptor 146
chr1_+_197237352 0.42 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
CRB1
crumbs homolog 1 (Drosophila)
chrX_-_55187588 0.41 ENST00000472571.2
ENST00000332132.4
ENST00000425133.2
ENST00000358460.4
FAM104B
family with sequence similarity 104, member B
chr11_+_57308979 0.41 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr16_-_25122785 0.41 ENST00000563962.1
ENST00000569920.1
RP11-449H11.1
RP11-449H11.1
chr22_-_38380543 0.41 ENST00000396884.2
SOX10
SRY (sex determining region Y)-box 10
chr10_+_81370689 0.41 ENST00000372308.3
ENST00000398636.3
ENST00000428376.2
ENST00000372313.5
ENST00000419470.2
ENST00000429958.1
ENST00000439264.1
SFTPA1
surfactant protein A1
chr15_-_20170354 0.41 ENST00000338912.5
IGHV1OR15-9
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr2_-_175629135 0.41 ENST00000409542.1
ENST00000409219.1
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr22_+_25595817 0.41 ENST00000215855.2
ENST00000404334.1
CRYBB3
crystallin, beta B3
chr21_-_47352477 0.41 ENST00000593412.1
PRED62
Uncharacterized protein
chr11_+_74811578 0.41 ENST00000531713.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr5_-_13944652 0.41 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr1_-_177939348 0.40 ENST00000464631.2
SEC16B
SEC16 homolog B (S. cerevisiae)
chr6_+_46661575 0.40 ENST00000450697.1
TDRD6
tudor domain containing 6
chr1_-_177939041 0.40 ENST00000308284.6
SEC16B
SEC16 homolog B (S. cerevisiae)
chr1_+_87012753 0.40 ENST00000370563.3
CLCA4
chloride channel accessory 4
chrX_-_31090152 0.39 ENST00000359202.3
FTHL17
ferritin, heavy polypeptide-like 17
chr7_-_22539771 0.39 ENST00000406890.2
ENST00000424363.1
STEAP1B
STEAP family member 1B
chr17_+_9728828 0.39 ENST00000262441.5
GLP2R
glucagon-like peptide 2 receptor
chr14_-_47812321 0.39 ENST00000357362.3
ENST00000486952.2
ENST00000426342.1
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr3_+_50229037 0.39 ENST00000232461.3
ENST00000433068.1
GNAT1
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr12_-_91573132 0.39 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr10_-_90751038 0.39 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr19_+_48876300 0.38 ENST00000600863.1
ENST00000601610.1
ENST00000595322.1
SYNGR4
synaptogyrin 4
chr17_+_27369918 0.38 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr11_+_60383204 0.38 ENST00000412599.1
ENST00000320202.4
LINC00301
long intergenic non-protein coding RNA 301
chr1_-_203155868 0.37 ENST00000255409.3
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr9_+_34992846 0.37 ENST00000443266.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr16_-_25122735 0.37 ENST00000563176.1
RP11-449H11.1
RP11-449H11.1
chr14_-_23504087 0.36 ENST00000493471.2
ENST00000460922.2
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr15_+_90895471 0.36 ENST00000354377.3
ENST00000379090.5
ZNF774
zinc finger protein 774
chr4_+_154125565 0.36 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr11_-_110968081 0.36 ENST00000603154.1
RP11-89C3.4
RP11-89C3.4
chr2_+_120189422 0.36 ENST00000306406.4
TMEM37
transmembrane protein 37
chr6_+_80816342 0.36 ENST00000369760.4
ENST00000356489.5
ENST00000320393.6
BCKDHB
branched chain keto acid dehydrogenase E1, beta polypeptide
chr10_-_81320151 0.35 ENST00000372325.2
ENST00000372327.5
ENST00000417041.1
SFTPA2
surfactant protein A2
chr11_+_22689648 0.35 ENST00000278187.3
GAS2
growth arrest-specific 2
chr7_+_117119187 0.35 ENST00000446805.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr5_+_110409012 0.35 ENST00000379706.4
TSLP
thymic stromal lymphopoietin
chr5_-_55412774 0.35 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr10_-_72542272 0.35 ENST00000545575.1
TBATA
thymus, brain and testes associated
chr16_+_4838393 0.35 ENST00000589721.1
SMIM22
small integral membrane protein 22
chrX_-_154255143 0.34 ENST00000453950.1
ENST00000423959.1
F8
coagulation factor VIII, procoagulant component
chr15_+_85427903 0.34 ENST00000286749.3
ENST00000394573.1
ENST00000537703.1
SLC28A1
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr8_-_27469383 0.34 ENST00000519742.1
CLU
clusterin
chr16_+_4838412 0.33 ENST00000589327.1
SMIM22
small integral membrane protein 22
chr8_-_110620284 0.33 ENST00000529690.1
SYBU
syntabulin (syntaxin-interacting)

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFF_MAFG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:1903717 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.6 2.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.5 3.5 GO:0008218 bioluminescence(GO:0008218)
0.4 1.2 GO:0035759 mesangial cell-matrix adhesion(GO:0035759) regulation of dendritic cell dendrite assembly(GO:2000547)
0.4 1.5 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.4 1.1 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.4 2.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 1.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 1.6 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.8 GO:0030185 nitric oxide transport(GO:0030185)
0.2 1.4 GO:0048241 epinephrine transport(GO:0048241)
0.2 0.9 GO:0042412 taurine biosynthetic process(GO:0042412)
0.2 0.7 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.2 2.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 1.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 1.4 GO:0046618 drug export(GO:0046618)
0.1 0.6 GO:0035377 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.6 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.1 0.8 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 2.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.6 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.3 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.9 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.1 0.4 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.3 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.4 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.1 0.5 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.4 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.6 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.6 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.2 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.3 GO:0003193 pulmonary valve formation(GO:0003193) visceral motor neuron differentiation(GO:0021524) foramen ovale closure(GO:0035922)
0.1 0.1 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.1 0.3 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.9 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.3 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 1.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 1.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 3.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.3 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.4 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.5 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.1 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 1.2 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.1 0.2 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 0.2 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.4 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 1.8 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.4 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 1.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.5 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 7.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.8 GO:0042117 monocyte activation(GO:0042117)
0.0 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.8 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.3 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.6 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.2 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.5 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.2 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.3 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0010157 response to chlorate(GO:0010157)
0.0 0.2 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.5 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.9 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.5 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0006090 pyruvate metabolic process(GO:0006090)
0.0 0.4 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.3 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.1 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.2 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.4 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.2 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 1.2 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.2 GO:0001558 regulation of cell growth(GO:0001558)
0.0 0.4 GO:0021670 lateral ventricle development(GO:0021670) outer dynein arm assembly(GO:0036158)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.7 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.3 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 1.0 GO:0051180 vitamin transport(GO:0051180)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 1.8 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 2.0 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 1.4 GO:2000257 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.4 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.6 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 1.1 GO:0006611 protein export from nucleus(GO:0006611)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0005602 complement component C1 complex(GO:0005602)
0.2 0.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 0.5 GO:0097447 dendritic tree(GO:0097447)
0.1 1.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.6 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 8.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.2 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.3 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.3 GO:0036019 endolysosome(GO:0036019)
0.1 1.9 GO:0032982 myosin filament(GO:0032982)
0.1 0.2 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.7 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.1 GO:0097227 sperm annulus(GO:0097227)
0.1 0.9 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.9 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.4 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.2 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 2.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 5.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.7 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.8 GO:0042599 lamellar body(GO:0042599)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.4 GO:0033391 chromatoid body(GO:0033391)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.0 0.4 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 1.5 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.9 GO:0030286 dynein complex(GO:0030286)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.0 GO:0034518 nuclear cap binding complex(GO:0005846) RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 4.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.6 3.5 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.5 1.9 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.3 2.1 GO:0030492 hemoglobin binding(GO:0030492)
0.3 1.2 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.3 1.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 0.8 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.3 2.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 1.0 GO:0008431 vitamin E binding(GO:0008431)
0.2 1.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.2 0.7 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.1 0.6 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 1.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.4 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.5 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.1 0.4 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 3.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.7 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.3 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 1.5 GO:1903136 cuprous ion binding(GO:1903136)
0.1 8.7 GO:0019843 rRNA binding(GO:0019843)
0.1 0.4 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.4 GO:0000035 acyl binding(GO:0000035)
0.1 0.3 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.3 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 1.9 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 2.1 GO:0031432 titin binding(GO:0031432)
0.1 0.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.2 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 1.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.2 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.1 0.4 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.2 GO:0004802 transketolase activity(GO:0004802)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 1.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.4 GO:0008199 ferric iron binding(GO:0008199)
0.0 1.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.9 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 1.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 1.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 3.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.0 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 4.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.4 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.0 0.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 6.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 2.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 3.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 7.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 2.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 3.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS