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Illumina Body Map 2, young vs old

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Results for MBD2

Z-value: 0.47

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Transcription factors associated with MBD2

Gene Symbol Gene ID Gene Info
ENSG00000134046.7 methyl-CpG binding domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MBD2hg19_v2_chr18_-_51750948_517510590.154.0e-01Click!

Activity profile of MBD2 motif

Sorted Z-values of MBD2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_42275153 4.52 ENST00000294964.5
protein kinase domain containing, cytoplasmic
chr6_-_45983581 3.09 ENST00000339561.6
chloride intracellular channel 5
chr6_-_45983549 2.96 ENST00000544153.1
chloride intracellular channel 5
chr6_+_17281573 2.84 ENST00000379052.5
RNA binding motif protein 24
chr2_+_220299547 2.72 ENST00000312358.7
SPEG complex locus
chr14_-_21566731 2.64 ENST00000360947.3
zinc finger protein 219
chr2_+_74212073 2.31 ENST00000441217.1
AC073046.25
chr20_-_590944 2.21 ENST00000246080.3
transcription factor 15 (basic helix-loop-helix)
chrY_+_2803322 2.05 ENST00000383052.1
ENST00000155093.3
ENST00000449237.1
ENST00000443793.1
zinc finger protein, Y-linked
chr7_+_128470431 2.02 ENST00000325888.8
ENST00000346177.6
filamin C, gamma
chr18_+_77155942 2.02 ENST00000397790.2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr11_-_46142948 2.00 ENST00000257821.4
PHD finger protein 21A
chr3_-_128206759 2.00 ENST00000430265.2
GATA binding protein 2
chr19_-_14201507 1.98 ENST00000533683.2
sterile alpha motif domain containing 1
chr1_+_110009215 1.89 ENST00000369872.3
synaptophysin-like 2
chr3_-_38691119 1.82 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
sodium channel, voltage-gated, type V, alpha subunit
chr1_+_110009150 1.81 ENST00000401021.3
synaptophysin-like 2
chr18_+_77155856 1.77 ENST00000253506.5
ENST00000591814.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr11_-_89224488 1.76 ENST00000534731.1
ENST00000527626.1
NADPH oxidase 4
chr7_-_150864635 1.73 ENST00000297537.4
gastrulation brain homeobox 1
chr2_+_46769798 1.67 ENST00000238738.4
ras homolog family member Q
chr19_-_14201776 1.67 ENST00000269724.5
sterile alpha motif domain containing 1
chr6_-_43596899 1.65 ENST00000307126.5
ENST00000452781.1
GTP binding protein 2
chr11_-_89224299 1.63 ENST00000343727.5
ENST00000531342.1
ENST00000375979.3
NADPH oxidase 4
chr1_+_43148625 1.60 ENST00000436427.1
Y box binding protein 1
chr12_+_54393880 1.59 ENST00000303450.4
homeobox C9
chr2_+_239756671 1.57 ENST00000448943.2
twist family bHLH transcription factor 2
chr12_+_68042517 1.55 ENST00000393555.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr8_+_30241995 1.51 ENST00000397323.4
ENST00000339877.4
ENST00000320203.4
ENST00000287771.5
RNA binding protein with multiple splicing
chr3_-_185542761 1.50 ENST00000457616.2
ENST00000346192.3
insulin-like growth factor 2 mRNA binding protein 2
chr10_-_17659234 1.50 ENST00000466335.1
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr19_-_36643329 1.50 ENST00000589154.1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr12_-_115121962 1.48 ENST00000349155.2
T-box 3
chr11_-_46142615 1.48 ENST00000529734.1
ENST00000323180.6
PHD finger protein 21A
chr1_+_43148059 1.45 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr8_+_30241934 1.44 ENST00000538486.1
RNA binding protein with multiple splicing
chr17_+_46125707 1.43 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
nuclear factor, erythroid 2-like 1
chr3_+_112930306 1.42 ENST00000495514.1
BOC cell adhesion associated, oncogene regulated
chr17_+_46126135 1.41 ENST00000361665.3
ENST00000585062.1
nuclear factor, erythroid 2-like 1
chr12_+_105724613 1.34 ENST00000549934.2
chromosome 12 open reading frame 75
chr12_+_3068957 1.30 ENST00000543035.1
TEA domain family member 4
chr15_-_65067773 1.29 ENST00000300069.4
RNA binding protein with multiple splicing 2
chr3_-_185542817 1.23 ENST00000382199.2
insulin-like growth factor 2 mRNA binding protein 2
chr19_+_6739662 1.23 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
thyroid hormone receptor interactor 10
chrX_+_68725084 1.22 ENST00000252338.4
family with sequence similarity 155, member B
chr2_+_220306745 1.21 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG complex locus
chr3_+_133292759 1.18 ENST00000431519.2
CDV3 homolog (mouse)
chr16_-_2059748 1.18 ENST00000562103.1
ENST00000431526.1
zinc finger protein 598
chr12_+_68042495 1.16 ENST00000344096.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr9_+_34989638 1.16 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr19_+_36545833 1.15 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WD repeat domain 62
chr17_+_46125685 1.15 ENST00000579889.1
nuclear factor, erythroid 2-like 1
chr7_-_19157248 1.12 ENST00000242261.5
twist family bHLH transcription factor 1
chr17_+_36861735 1.11 ENST00000378137.5
ENST00000325718.7
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr3_-_133969437 1.11 ENST00000460933.1
ENST00000296084.4
receptor-like tyrosine kinase
chr16_-_2059797 1.10 ENST00000563630.1
zinc finger protein 598
chr22_+_19419425 1.07 ENST00000333130.3
mitochondrial ribosomal protein L40
chr11_-_89224508 1.07 ENST00000525196.1
NADPH oxidase 4
chr2_+_220306238 1.07 ENST00000435853.1
SPEG complex locus
chr3_+_112930373 1.07 ENST00000498710.1
BOC cell adhesion associated, oncogene regulated
chr2_-_119605253 1.07 ENST00000295206.6
engrailed homeobox 1
chr18_+_19750894 1.03 ENST00000581694.1
GATA binding protein 6
chr11_-_89224139 1.02 ENST00000413594.2
NADPH oxidase 4
chr14_-_61190754 1.02 ENST00000216513.4
SIX homeobox 4
chr19_-_11308190 1.01 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KN motif and ankyrin repeat domains 2
chr8_-_141645645 1.01 ENST00000519980.1
ENST00000220592.5
argonaute RISC catalytic component 2
chr1_-_27693349 1.01 ENST00000374040.3
ENST00000357582.2
ENST00000493901.1
mitogen-activated protein kinase kinase kinase 6
chr9_-_130617029 1.00 ENST00000373203.4
endoglin
chr8_-_145688231 0.99 ENST00000530374.1
cysteine/histidine-rich 1
chr6_+_160390102 0.98 ENST00000356956.1
insulin-like growth factor 2 receptor
chr6_+_149638876 0.98 ENST00000392282.1
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr12_+_122516626 0.97 ENST00000319080.7
MLX interacting protein
chr9_+_124413873 0.96 ENST00000408936.3
DAB2 interacting protein
chr3_+_133292574 0.96 ENST00000264993.3
CDV3 homolog (mouse)
chr1_+_46269248 0.96 ENST00000361297.2
ENST00000372009.2
microtubule associated serine/threonine kinase 2
chr9_-_130616915 0.96 ENST00000344849.3
endoglin
chr4_+_48343339 0.93 ENST00000264313.6
SLAIN motif family, member 2
chr1_+_145611010 0.92 ENST00000369291.5
ring finger protein 115
chr12_-_48213735 0.92 ENST00000417902.1
ENST00000417107.1
histone deacetylase 7
chr12_-_57400227 0.92 ENST00000300101.2
zinc finger and BTB domain containing 39
chr2_-_54197915 0.91 ENST00000404125.1
proteasome (prosome, macropain) activator subunit 4
chr11_-_89224638 0.91 ENST00000535633.1
ENST00000263317.4
NADPH oxidase 4
chr15_-_42783303 0.91 ENST00000565380.1
ENST00000564754.1
zinc finger protein 106
chr11_-_2160611 0.91 ENST00000416167.2
insulin-like growth factor 2 (somatomedin A)
chr19_+_11650709 0.90 ENST00000586059.1
calponin 1, basic, smooth muscle
chr6_+_1610681 0.89 ENST00000380874.2
forkhead box C1
chr12_-_29936731 0.88 ENST00000552618.1
ENST00000539277.1
ENST00000551659.1
transmembrane and tetratricopeptide repeat containing 1
chr10_-_17659357 0.87 ENST00000326961.6
ENST00000361271.3
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr9_-_112260531 0.87 ENST00000374541.2
ENST00000262539.3
protein tyrosine phosphatase, non-receptor type 3
chr7_+_74379083 0.86 ENST00000361825.7
GATS protein-like 1
chr11_-_2160180 0.86 ENST00000381406.4
insulin-like growth factor 2 (somatomedin A)
chr16_-_4166186 0.84 ENST00000294016.3
adenylate cyclase 9
chr17_-_27949911 0.84 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
coronin 6
chr19_+_18496957 0.83 ENST00000252809.3
growth differentiation factor 15
chr7_+_129710350 0.83 ENST00000335420.5
ENST00000463413.1
kelch domain containing 10
chr20_-_60640866 0.82 ENST00000252996.4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr12_+_110719032 0.79 ENST00000395494.2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr16_-_49890016 0.79 ENST00000563137.2
zinc finger protein 423
chr16_+_75033210 0.79 ENST00000566250.1
ENST00000567962.1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr3_-_48885228 0.79 ENST00000454963.1
ENST00000296446.8
ENST00000419216.1
ENST00000265563.8
protein kinase, cAMP-dependent, regulatory, type II, alpha
chr6_+_139456226 0.78 ENST00000367658.2
headcase homolog (Drosophila)
chr6_-_31763276 0.77 ENST00000440048.1
valyl-tRNA synthetase
chr7_-_100493482 0.76 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
acetylcholinesterase (Yt blood group)
chr15_-_56035177 0.76 ENST00000389286.4
ENST00000561292.1
protogenin
chr17_+_27920486 0.75 ENST00000394859.3
ankyrin repeat domain 13B
chr2_+_241375069 0.75 ENST00000264039.2
glypican 1
chr3_+_133292851 0.74 ENST00000503932.1
CDV3 homolog (mouse)
chr1_-_179851611 0.74 ENST00000610272.1
RP11-533E19.7
chr3_-_53080047 0.74 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
Scm-like with four mbt domains 1
chr12_-_49182783 0.73 ENST00000550422.1
adenylate cyclase 6
chr20_+_60878005 0.73 ENST00000253003.2
adhesion regulating molecule 1
chrX_+_24167746 0.72 ENST00000428571.1
ENST00000539115.1
zinc finger protein, X-linked
chr8_+_61592073 0.72 ENST00000526846.1
chromodomain helicase DNA binding protein 7
chr8_-_57123815 0.71 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
pleiomorphic adenoma gene 1
chr2_+_219264762 0.71 ENST00000452977.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr3_-_124774802 0.70 ENST00000311127.4
heart development protein with EGF-like domains 1
chr16_+_1823208 0.70 ENST00000568449.1
ENST00000307394.7
essential meiotic structure-specific endonuclease subunit 2
chr16_-_30905584 0.69 ENST00000380317.4
B-cell CLL/lymphoma 7C
chr7_-_139876812 0.68 ENST00000397560.2
lysine (K)-specific demethylase 7A
chr12_+_120972147 0.68 ENST00000325954.4
ENST00000542438.1
ring finger protein 10
chrX_-_154255143 0.67 ENST00000453950.1
ENST00000423959.1
coagulation factor VIII, procoagulant component
chr20_+_34894247 0.67 ENST00000373913.3
discs, large (Drosophila) homolog-associated protein 4
chr12_-_57824561 0.67 ENST00000448732.1
R3H domain containing 2
chr3_-_98620500 0.67 ENST00000326840.6
discoidin, CUB and LCCL domain containing 2
chr14_-_89883412 0.67 ENST00000557258.1
forkhead box N3
chr14_-_75593708 0.67 ENST00000557673.1
ENST00000238616.5
NIMA-related kinase 9
chr19_-_11373128 0.66 ENST00000294618.7
dedicator of cytokinesis 6
chr3_+_112930387 0.65 ENST00000485230.1
BOC cell adhesion associated, oncogene regulated
chr20_-_16554078 0.65 ENST00000354981.2
ENST00000355755.3
ENST00000378003.2
ENST00000408042.1
kinesin family member 16B
chr1_+_28844778 0.65 ENST00000411533.1
regulator of chromosome condensation 1
chr2_-_118771701 0.65 ENST00000376300.2
ENST00000319432.5
coiled-coil domain containing 93
chr5_-_127873659 0.63 ENST00000262464.4
fibrillin 2
chr10_-_79686284 0.63 ENST00000372391.2
ENST00000372388.2
discs, large homolog 5 (Drosophila)
chr3_-_88108192 0.62 ENST00000309534.6
CGG triplet repeat binding protein 1
chr11_+_45168182 0.61 ENST00000526442.1
PR domain containing 11
chr7_-_100493744 0.61 ENST00000428317.1
ENST00000441605.1
acetylcholinesterase (Yt blood group)
chrX_-_17879356 0.60 ENST00000331511.1
ENST00000415486.3
ENST00000545871.1
ENST00000451717.1
retinoic acid induced 2
chr12_-_57824739 0.60 ENST00000347140.3
ENST00000402412.1
R3H domain containing 2
chr2_-_100106419 0.60 ENST00000393445.3
ENST00000258428.3
REV1, polymerase (DNA directed)
chr3_+_112930946 0.60 ENST00000462425.1
BOC cell adhesion associated, oncogene regulated
chr5_-_127873496 0.59 ENST00000508989.1
fibrillin 2
chr17_+_80477571 0.59 ENST00000335255.5
forkhead box K2
chr11_-_89224667 0.59 ENST00000393282.2
NADPH oxidase 4
chr5_-_180076580 0.59 ENST00000502649.1
fms-related tyrosine kinase 4
chr18_-_51750948 0.58 ENST00000583046.1
ENST00000398398.2
methyl-CpG binding domain protein 2
chr19_+_35491174 0.58 ENST00000317991.5
ENST00000504615.2
GRAM domain containing 1A
chr12_+_120972606 0.58 ENST00000413266.2
ring finger protein 10
chr3_+_33155525 0.58 ENST00000449224.1
cartilage associated protein
chr5_-_180076613 0.58 ENST00000261937.6
ENST00000393347.3
fms-related tyrosine kinase 4
chr9_-_136933092 0.58 ENST00000357885.2
bromodomain containing 3
chr1_+_27561007 0.57 ENST00000319394.3
WD and tetratricopeptide repeats 1
chr3_-_176915036 0.57 ENST00000427349.1
ENST00000352800.5
transducin (beta)-like 1 X-linked receptor 1
chr3_-_88108212 0.56 ENST00000482016.1
CGG triplet repeat binding protein 1
chr19_+_10527449 0.56 ENST00000592685.1
ENST00000380702.2
phosphodiesterase 4A, cAMP-specific
chr4_-_78740511 0.55 ENST00000504123.1
ENST00000264903.4
ENST00000515441.1
CCR4-NOT transcription complex, subunit 6-like
chr11_-_14380664 0.55 ENST00000545643.1
ENST00000256196.4
related RAS viral (r-ras) oncogene homolog 2
chr1_-_21503337 0.55 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
eukaryotic translation initiation factor 4 gamma, 3
chr12_+_122064673 0.55 ENST00000537188.1
ORAI calcium release-activated calcium modulator 1
chr5_-_72744336 0.55 ENST00000499003.3
forkhead box D1
chr3_-_113415441 0.54 ENST00000491165.1
ENST00000316407.4
KIAA2018
chr1_+_200011711 0.54 ENST00000544748.1
nuclear receptor subfamily 5, group A, member 2
chr19_+_56152262 0.54 ENST00000325333.5
ENST00000590190.1
zinc finger protein 580
chr8_+_37654424 0.53 ENST00000315215.7
G protein-coupled receptor 124
chr16_-_23160591 0.53 ENST00000219689.7
ubiquitin specific peptidase 31
chr17_+_17942594 0.53 ENST00000268719.4
GID complex subunit 4
chr10_+_70661014 0.53 ENST00000373585.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr16_+_29817399 0.53 ENST00000545521.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr7_+_130794878 0.53 ENST00000416992.2
muskelin 1, intracellular mediator containing kelch motifs
chr19_-_17356697 0.52 ENST00000291442.3
nuclear receptor subfamily 2, group F, member 6
chr7_+_130794846 0.52 ENST00000421797.2
muskelin 1, intracellular mediator containing kelch motifs
chr10_-_103880209 0.52 ENST00000425280.1
LIM domain binding 1
chr1_+_156084461 0.52 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
lamin A/C
chr2_-_242212227 0.52 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
high density lipoprotein binding protein
chr18_+_56530794 0.52 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
zinc finger protein 532
chr2_+_219264466 0.52 ENST00000273062.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chrX_-_134049262 0.52 ENST00000370783.3
motile sperm domain containing 1
chr14_+_71374122 0.51 ENST00000304743.2
ENST00000238570.5
pecanex homolog (Drosophila)
chr3_-_133969673 0.51 ENST00000427044.2
receptor-like tyrosine kinase
chr19_+_39904168 0.51 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr1_+_82266053 0.51 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
latrophilin 2
chr8_+_37654693 0.51 ENST00000412232.2
G protein-coupled receptor 124
chr19_+_56154913 0.50 ENST00000270451.5
ENST00000588537.1
zinc finger protein 581
chr6_-_31763721 0.50 ENST00000375663.3
valyl-tRNA synthetase
chr9_+_35829208 0.50 ENST00000439587.2
ENST00000377991.4
transmembrane protein 8B
chr13_-_80915059 0.50 ENST00000377104.3
sprouty homolog 2 (Drosophila)
chr17_+_48133459 0.50 ENST00000320031.8
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr10_+_124895472 0.49 ENST00000357878.5
H6 family homeobox 3
chr12_-_48213568 0.49 ENST00000080059.7
ENST00000354334.3
ENST00000430670.1
ENST00000552960.1
ENST00000440293.1
histone deacetylase 7
chr14_+_105886150 0.47 ENST00000331320.7
ENST00000406191.1
metastasis associated 1
chr11_-_64545941 0.47 ENST00000377387.1
splicing factor 1
chr11_-_67169265 0.47 ENST00000358239.4
ENST00000376745.4
protein phosphatase 1, catalytic subunit, alpha isozyme
chr1_+_9648921 0.46 ENST00000377376.4
ENST00000340305.5
ENST00000340381.6
transmembrane protein 201
chr15_+_80351977 0.46 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
zinc finger, AN1-type domain 6
chr22_-_19419205 0.46 ENST00000340170.4
ENST00000263208.5
histone cell cycle regulator
chr19_-_40791302 0.46 ENST00000392038.2
ENST00000578123.1
v-akt murine thymoma viral oncogene homolog 2
chr6_+_4776580 0.46 ENST00000397588.3
chromodomain protein, Y-like
chrX_-_17878827 0.45 ENST00000360011.1
retinoic acid induced 2
chr11_-_46142505 0.45 ENST00000524497.1
ENST00000418153.2
PHD finger protein 21A
chr5_+_14143728 0.45 ENST00000344204.4
ENST00000537187.1
trio Rho guanine nucleotide exchange factor
chr1_+_27561104 0.45 ENST00000361771.3
WD and tetratricopeptide repeats 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MBD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0001300 chronological cell aging(GO:0001300)
0.6 2.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.5 2.0 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.5 1.5 GO:0060931 sinoatrial node cell development(GO:0060931)
0.5 4.5 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.4 1.5 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.3 0.3 GO:0060928 cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.3 1.7 GO:0019230 proprioception(GO:0019230)
0.3 1.0 GO:0007493 endodermal cell fate determination(GO:0007493)
0.3 1.4 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.3 1.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3 6.0 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.3 0.9 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.3 0.8 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.3 3.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.3 2.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.3 1.6 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.3 1.1 GO:0061743 motor learning(GO:0061743)
0.3 0.8 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.3 1.0 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.3 0.8 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.2 0.7 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 1.8 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2 2.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2 1.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.2 1.0 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.7 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.2 0.5 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.2 0.5 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.2 1.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.2 0.5 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.2 6.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 0.4 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 1.0 GO:0090625 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 1.3 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.7 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1 0.7 GO:0035617 stress granule disassembly(GO:0035617)
0.1 3.5 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.4 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.1 1.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.4 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.8 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.5 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.7 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 1.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.8 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 0.5 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 3.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.6 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 4.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 1.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.9 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 1.0 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 1.9 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 0.4 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 1.3 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.5 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.1 0.5 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.5 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 0.5 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 1.2 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 1.2 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.1 0.3 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.5 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.3 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 3.8 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.3 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.2 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 0.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 0.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.7 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.9 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.2 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0061184 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) positive regulation of dermatome development(GO:0061184) renal vesicle induction(GO:0072034) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.1 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0003064 regulation of heart rate by hormone(GO:0003064)
0.0 1.0 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.7 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.6 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.7 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.7 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 2.8 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.3 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.6 GO:0060613 fat pad development(GO:0060613)
0.0 0.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.4 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.0 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.4 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.3 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 1.0 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.7 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 2.7 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.2 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 1.5 GO:0007099 centriole replication(GO:0007099)
0.0 1.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 2.0 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.9 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.5 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.5 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.5 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097)
0.0 0.7 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.9 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.7 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.8 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.5 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 2.7 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 1.8 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.0 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.8 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:0048617 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.6 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.9 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.0 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.5 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.0 0.2 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0044321 response to leptin(GO:0044321)
0.0 0.5 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.3 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.9 GO:0035329 hippo signaling(GO:0035329)
0.0 0.7 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.4 GO:0044804 nucleophagy(GO:0044804)
0.0 0.2 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.0 1.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.2 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.4 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.8 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.5 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.1 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 1.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.0 0.1 GO:1904753 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.0 0.2 GO:0006914 autophagy(GO:0006914)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.4 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.8 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 1.4 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0072563 endothelial microparticle(GO:0072563)
0.3 1.0 GO:1990032 parallel fiber(GO:1990032)
0.3 7.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 3.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.2 0.6 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 0.4 GO:0008623 CHRAC(GO:0008623)
0.1 0.7 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 3.7 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.5 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 3.0 GO:0005685 U1 snRNP(GO:0005685)
0.1 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.4 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 1.0 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 1.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.6 GO:0071203 WASH complex(GO:0071203)
0.1 0.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.5 GO:0045298 tubulin complex(GO:0045298)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.5 GO:0005682 U5 snRNP(GO:0005682)
0.1 6.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 4.0 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.4 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.8 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.5 GO:0005638 lamin filament(GO:0005638)
0.1 2.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0042587 glycogen granule(GO:0042587)
0.0 1.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 2.0 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0097413 Lewy body(GO:0097413)
0.0 4.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 1.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.5 GO:0000346 transcription export complex(GO:0000346)
0.0 1.8 GO:0016235 aggresome(GO:0016235)
0.0 1.5 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.2 GO:0043679 axon terminus(GO:0043679)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 1.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 7.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 1.5 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 0.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.5 1.8 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.4 3.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.4 1.7 GO:0032427 GBD domain binding(GO:0032427)
0.4 1.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.4 1.2 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.4 3.8 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.3 1.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.3 1.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.3 0.8 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.3 1.0 GO:0098808 mRNA cap binding(GO:0098808)
0.2 2.0 GO:0005534 galactose binding(GO:0005534)
0.2 1.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.2 2.6 GO:0004969 histamine receptor activity(GO:0004969)
0.2 1.6 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 0.6 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 1.0 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.4 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 0.5 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.4 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 5.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.3 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 1.0 GO:0043199 sulfate binding(GO:0043199)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 2.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 4.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 2.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.4 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 4.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.5 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 1.9 GO:0005521 lamin binding(GO:0005521)
0.0 0.6 GO:0038132 neuregulin binding(GO:0038132)
0.0 2.0 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 4.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 1.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 1.4 GO:0043236 laminin binding(GO:0043236)
0.0 2.3 GO:0043022 ribosome binding(GO:0043022)
0.0 0.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.4 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 3.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 3.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.2 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.7 GO:0071949 FAD binding(GO:0071949)
0.0 5.1 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 1.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.4 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.0 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 10.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 4.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.2 PID ALK1 PATHWAY ALK1 signaling events
0.1 3.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 3.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 2.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 3.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.9 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 3.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 2.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription