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Illumina Body Map 2, young vs old

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Results for MEF2D_MEF2A

Z-value: 0.26

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Transcription factors associated with MEF2D_MEF2A

Gene Symbol Gene ID Gene Info
MEF2D
ENSG00000116604.13 myocyte enhancer factor 2D
MEF2A
ENSG00000068305.13 myocyte enhancer factor 2A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Ahg19_v2_chr15_+_100106244_1001062920.421.6e-02Click!
MEF2Dhg19_v2_chr1_-_156460391_1564604170.402.5e-02Click!

Activity profile of MEF2D_MEF2A motif

Sorted Z-values of MEF2D_MEF2A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_19223523 72.82 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr7_-_113559104 68.71 ENST00000284601.3
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr1_-_201391149 59.71 ENST00000555948.1
ENST00000556362.1
TNNI1
troponin I type 1 (skeletal, slow)
chr2_+_168043793 59.44 ENST00000409273.1
ENST00000409605.1
XIRP2
xin actin-binding repeat containing 2
chr17_+_37821593 59.34 ENST00000578283.1
TCAP
titin-cap
chr6_-_123957942 59.30 ENST00000398178.3
TRDN
triadin
chr6_-_123958051 55.87 ENST00000546248.1
TRDN
triadin
chr2_+_88367299 55.78 ENST00000419482.2
ENST00000444564.2
SMYD1
SET and MYND domain containing 1
chr16_-_31439735 54.77 ENST00000287490.4
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr10_-_115423792 53.97 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
NRAP
nebulin-related anchoring protein
chr12_-_111358372 51.77 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr6_-_123958111 51.22 ENST00000542443.1
TRDN
triadin
chr2_-_211168332 50.56 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chrX_-_21776281 48.60 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr3_-_39234074 48.36 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
XIRP1
xin actin-binding repeat containing 1
chr2_+_88367368 47.88 ENST00000438570.1
SMYD1
SET and MYND domain containing 1
chr5_+_53751445 41.61 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr1_-_917497 41.31 ENST00000433179.2
C1orf170
chromosome 1 open reading frame 170
chr10_+_50507232 40.45 ENST00000374144.3
C10orf71
chromosome 10 open reading frame 71
chr5_+_191592 38.21 ENST00000328278.3
LRRC14B
leucine rich repeat containing 14B
chr1_-_917466 36.99 ENST00000341290.2
C1orf170
chromosome 1 open reading frame 170
chr10_+_50507181 36.79 ENST00000323868.4
C10orf71
chromosome 10 open reading frame 71
chr4_+_120056939 33.62 ENST00000307128.5
MYOZ2
myozenin 2
chr10_-_75415825 33.38 ENST00000394810.2
SYNPO2L
synaptopodin 2-like
chr8_+_1993152 32.65 ENST00000262113.4
MYOM2
myomesin 2
chr22_-_36013368 31.52 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chrX_-_15332665 31.26 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr11_+_1942580 31.00 ENST00000381558.1
TNNT3
troponin T type 3 (skeletal, fast)
chr3_-_52486841 30.69 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr8_+_1993173 29.87 ENST00000523438.1
MYOM2
myomesin 2
chr22_+_26138108 29.85 ENST00000536101.1
ENST00000335473.7
ENST00000407587.2
MYO18B
myosin XVIIIB
chr1_-_100643765 29.56 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39
leucine rich repeat containing 39
chr10_+_88428370 29.51 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3
LIM domain binding 3
chr17_-_9694614 29.24 ENST00000330255.5
ENST00000571134.1
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chr6_-_123958141 29.20 ENST00000334268.4
TRDN
triadin
chr14_-_23877474 28.82 ENST00000405093.3
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr12_-_49393092 28.71 ENST00000421952.2
DDN
dendrin
chr2_-_211179883 28.46 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr3_+_121311966 28.40 ENST00000338040.4
FBXO40
F-box protein 40
chr1_-_26394114 28.36 ENST00000374272.3
TRIM63
tripartite motif containing 63, E3 ubiquitin protein ligase
chr11_+_1940925 28.17 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
TNNT3
troponin T type 3 (skeletal, fast)
chr7_-_150884332 27.90 ENST00000275838.1
ENST00000422024.1
ENST00000434669.1
ASB10
ankyrin repeat and SOCS box containing 10
chr16_+_31225337 27.52 ENST00000322122.3
TRIM72
tripartite motif containing 72
chr22_-_36018569 26.99 ENST00000419229.1
ENST00000406324.1
MB
myoglobin
chr20_+_61147651 26.29 ENST00000370527.3
ENST00000370524.2
C20orf166
chromosome 20 open reading frame 166
chr11_+_1860200 25.31 ENST00000381911.1
TNNI2
troponin I type 2 (skeletal, fast)
chr5_+_78985673 25.09 ENST00000446378.2
CMYA5
cardiomyopathy associated 5
chr12_+_101962128 24.74 ENST00000550514.1
MYBPC1
myosin binding protein C, slow type
chr9_-_97356075 24.46 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr10_+_88428206 24.44 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3
LIM domain binding 3
chrX_-_63450480 24.27 ENST00000362002.2
ASB12
ankyrin repeat and SOCS box containing 12
chr3_+_35683651 24.22 ENST00000187397.4
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr4_+_119810134 23.96 ENST00000434046.2
SYNPO2
synaptopodin 2
chr1_+_145413268 23.31 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
HFE2
hemochromatosis type 2 (juvenile)
chr18_-_3219847 23.27 ENST00000261606.7
MYOM1
myomesin 1
chr2_+_170366203 23.16 ENST00000284669.1
KLHL41
kelch-like family member 41
chr1_-_115238207 23.08 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
AMPD1
adenosine monophosphate deaminase 1
chr17_-_10421853 22.32 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr18_-_3220106 22.22 ENST00000356443.4
ENST00000400569.3
MYOM1
myomesin 1
chr10_-_75410771 21.91 ENST00000372873.4
SYNPO2L
synaptopodin 2-like
chr4_+_119809984 21.88 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2
synaptopodin 2
chr1_+_160160283 21.82 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_+_160160346 21.75 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr16_+_7382745 21.64 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr17_+_7184986 21.26 ENST00000317370.8
ENST00000571308.1
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr11_+_57308979 21.10 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr7_-_150884873 20.97 ENST00000377867.3
ASB10
ankyrin repeat and SOCS box containing 10
chr17_+_4855053 20.63 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr19_+_3933085 19.89 ENST00000168977.2
ENST00000599576.1
NMRK2
nicotinamide riboside kinase 2
chr15_+_42651691 19.65 ENST00000357568.3
ENST00000349748.3
ENST00000318023.7
ENST00000397163.3
CAPN3
calpain 3, (p94)
chr2_+_220299547 19.63 ENST00000312358.7
SPEG
SPEG complex locus
chr2_+_103378472 19.44 ENST00000412401.2
TMEM182
transmembrane protein 182
chr19_+_3933579 18.56 ENST00000593949.1
NMRK2
nicotinamide riboside kinase 2
chr3_+_42727011 18.12 ENST00000287777.4
KLHL40
kelch-like family member 40
chr6_+_53948221 18.01 ENST00000460844.2
MLIP
muscular LMNA-interacting protein
chr12_+_101988627 17.48 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr5_-_142077569 17.43 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
FGF1
fibroblast growth factor 1 (acidic)
chr6_+_53948328 17.16 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chrX_+_153046456 17.09 ENST00000393786.3
ENST00000370104.1
ENST00000370108.3
ENST00000370101.3
ENST00000430541.1
ENST00000370100.1
SRPK3
SRSF protein kinase 3
chr6_+_41021027 17.00 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr22_-_51017084 16.31 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr1_-_116311402 16.00 ENST00000261448.5
CASQ2
calsequestrin 2 (cardiac muscle)
chr22_-_51016846 15.89 ENST00000312108.7
ENST00000395650.2
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr11_+_1860832 15.50 ENST00000252898.7
TNNI2
troponin I type 2 (skeletal, fast)
chr7_-_44105158 15.24 ENST00000297283.3
PGAM2
phosphoglycerate mutase 2 (muscle)
chr3_+_135741576 15.20 ENST00000334546.2
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr1_-_116311323 15.13 ENST00000456138.2
CASQ2
calsequestrin 2 (cardiac muscle)
chr15_+_65369082 15.11 ENST00000432196.2
KBTBD13
kelch repeat and BTB (POZ) domain containing 13
chr10_-_69455873 14.67 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr12_-_22094336 14.60 ENST00000326684.4
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr5_+_155753745 14.32 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr3_-_155011483 14.25 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr10_-_69425399 14.15 ENST00000330298.6
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr1_+_160085567 13.90 ENST00000392233.3
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr1_-_201390846 13.88 ENST00000367312.1
ENST00000555340.2
ENST00000361379.4
TNNI1
troponin I type 1 (skeletal, slow)
chr3_-_196242233 13.78 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr1_+_160085501 13.65 ENST00000361216.3
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr1_+_228395755 13.61 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr2_+_239047337 13.56 ENST00000409223.1
ENST00000305959.4
KLHL30
kelch-like family member 30
chr12_-_22094159 13.56 ENST00000538350.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr17_-_79900255 13.49 ENST00000330655.3
ENST00000582198.1
MYADML2
PYCR1
myeloid-associated differentiation marker-like 2
pyrroline-5-carboxylate reductase 1
chr2_-_97509749 13.33 ENST00000331001.2
ENST00000318357.4
ANKRD23
ankyrin repeat domain 23
chr16_-_4292071 13.10 ENST00000399609.3
SRL
sarcalumenin
chr17_-_41132088 13.05 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr11_+_1860682 12.94 ENST00000381906.1
TNNI2
troponin I type 2 (skeletal, fast)
chr2_-_97509729 12.94 ENST00000418232.1
ANKRD23
ankyrin repeat domain 23
chr15_-_83474806 12.88 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr12_+_81101277 12.86 ENST00000228641.3
MYF6
myogenic factor 6 (herculin)
chr12_+_119616447 12.77 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr11_+_1940786 12.76 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
TNNT3
troponin T type 3 (skeletal, fast)
chr3_+_127634069 12.74 ENST00000405109.1
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr11_-_47374246 12.74 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
MYBPC3
myosin binding protein C, cardiac
chr1_-_216896780 12.71 ENST00000459955.1
ENST00000366937.1
ENST00000408911.3
ENST00000391890.3
ESRRG
estrogen-related receptor gamma
chr7_+_143013198 12.48 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr11_+_3666335 12.38 ENST00000250693.1
ART1
ADP-ribosyltransferase 1
chr8_-_70745575 12.08 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr1_-_40137710 11.85 ENST00000235628.1
NT5C1A
5'-nucleotidase, cytosolic IA
chr14_-_21493884 11.78 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2
NDRG family member 2
chr17_-_42188598 11.72 ENST00000591714.1
HDAC5
histone deacetylase 5
chr13_+_76378305 11.71 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr1_-_31845914 11.70 ENST00000373713.2
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr4_-_100575781 11.65 ENST00000511828.1
RP11-766F14.2
Protein LOC285556
chr5_-_16509101 11.48 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr17_-_27949911 11.43 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6
coronin 6
chr3_+_127634312 11.33 ENST00000407609.3
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr7_+_28448995 11.11 ENST00000424599.1
CREB5
cAMP responsive element binding protein 5
chr4_+_186064395 11.00 ENST00000281456.6
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr14_-_21493649 10.93 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2
NDRG family member 2
chr2_-_179537145 10.84 ENST00000448510.2
TTN
titin
chr17_+_65040678 10.76 ENST00000226021.3
CACNG1
calcium channel, voltage-dependent, gamma subunit 1
chr2_-_219696519 10.58 ENST00000545803.1
ENST00000430489.1
ENST00000392098.3
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr3_+_179370517 10.52 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr10_-_72141330 10.38 ENST00000395011.1
ENST00000395010.1
LRRC20
leucine rich repeat containing 20
chr2_-_219696511 10.29 ENST00000439262.2
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr6_-_3912207 10.15 ENST00000566733.1
RP1-140K8.5
RP1-140K8.5
chr4_+_41362796 10.11 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1
LIM and calponin homology domains 1
chr12_+_52431016 10.09 ENST00000553200.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr3_-_46904946 9.87 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr17_-_10372875 9.85 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr3_-_46904918 9.72 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr4_+_95373037 9.65 ENST00000359265.4
ENST00000437932.1
ENST00000380180.3
ENST00000318007.5
ENST00000450793.1
ENST00000538141.1
ENST00000317968.4
ENST00000512274.1
ENST00000503974.1
ENST00000504489.1
ENST00000542407.1
PDLIM5
PDZ and LIM domain 5
chr9_-_85882145 9.63 ENST00000328788.1
FRMD3
FERM domain containing 3
chr3_+_35683775 9.62 ENST00000452563.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr2_+_179149636 9.49 ENST00000409631.1
OSBPL6
oxysterol binding protein-like 6
chr16_+_30075463 9.41 ENST00000562168.1
ENST00000569545.1
ALDOA
aldolase A, fructose-bisphosphate
chr16_+_30075595 9.38 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chr3_-_57326704 9.26 ENST00000487349.1
ENST00000389601.3
ASB14
ankyrin repeat and SOCS box containing 14
chr9_-_130639997 9.17 ENST00000373176.1
AK1
adenylate kinase 1
chr3_-_192445289 9.08 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12
fibroblast growth factor 12
chr2_+_220283091 9.00 ENST00000373960.3
DES
desmin
chr8_+_67039278 8.94 ENST00000276573.7
ENST00000350034.4
TRIM55
tripartite motif containing 55
chr3_+_138067521 8.73 ENST00000494949.1
MRAS
muscle RAS oncogene homolog
chr16_+_6069072 8.73 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr19_+_35630022 8.69 ENST00000589209.1
FXYD1
FXYD domain containing ion transport regulator 1
chr9_+_100263912 8.62 ENST00000259365.4
TMOD1
tropomodulin 1
chr12_-_57644952 8.61 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3
SH3 and cysteine rich domain 3
chr1_-_216896674 8.51 ENST00000475275.1
ENST00000469486.1
ENST00000481543.1
ESRRG
estrogen-related receptor gamma
chr3_+_35683816 8.30 ENST00000438577.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr13_+_76378407 8.22 ENST00000447038.1
LMO7
LIM domain 7
chr1_+_150254936 8.12 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr14_-_70546897 8.08 ENST00000394330.2
ENST00000533541.1
ENST00000216568.7
SLC8A3
solute carrier family 8 (sodium/calcium exchanger), member 3
chr4_-_23891658 8.07 ENST00000507380.1
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr8_+_67039131 8.04 ENST00000315962.4
ENST00000353317.5
TRIM55
tripartite motif containing 55
chr16_+_30075783 8.04 ENST00000412304.2
ALDOA
aldolase A, fructose-bisphosphate
chr13_+_76413852 8.03 ENST00000533809.2
LMO7
LIM domain 7
chr6_-_76203345 7.93 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr5_+_173316341 7.93 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr16_+_30076052 7.93 ENST00000563987.1
ALDOA
aldolase A, fructose-bisphosphate
chrX_-_138304939 7.87 ENST00000448673.1
FGF13
fibroblast growth factor 13
chr19_+_35630344 7.84 ENST00000455515.2
FXYD1
FXYD domain containing ion transport regulator 1
chr4_+_41362615 7.82 ENST00000509638.1
LIMCH1
LIM and calponin homology domains 1
chr4_-_44653636 7.79 ENST00000415895.4
ENST00000332990.5
YIPF7
Yip1 domain family, member 7
chr6_-_76203454 7.79 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr4_+_114066764 7.77 ENST00000511380.1
ANK2
ankyrin 2, neuronal
chr1_+_170633047 7.62 ENST00000239461.6
ENST00000497230.2
PRRX1
paired related homeobox 1
chr11_+_112832090 7.62 ENST00000533760.1
NCAM1
neural cell adhesion molecule 1
chr10_+_86184676 7.44 ENST00000543283.1
CCSER2
coiled-coil serine-rich protein 2
chr17_-_27467418 7.24 ENST00000528564.1
MYO18A
myosin XVIIIA
chr10_-_14880002 7.12 ENST00000465530.1
CDNF
cerebral dopamine neurotrophic factor
chr13_+_76210448 7.08 ENST00000377499.5
LMO7
LIM domain 7
chrX_+_70521584 7.04 ENST00000373829.3
ENST00000538820.1
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr6_-_45983581 7.02 ENST00000339561.6
CLIC5
chloride intracellular channel 5
chr19_+_35629702 7.02 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr1_-_203144941 7.00 ENST00000255416.4
MYBPH
myosin binding protein H
chr11_+_112832202 6.97 ENST00000534015.1
NCAM1
neural cell adhesion molecule 1
chr22_+_17956618 6.95 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr5_+_133772383 6.86 ENST00000513329.1
AC005355.1
AC005355.1
chr9_-_33402506 6.84 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7
aquaporin 7
chr6_-_45983549 6.75 ENST00000544153.1
CLIC5
chloride intracellular channel 5
chr3_+_138067314 6.64 ENST00000423968.2
MRAS
muscle RAS oncogene homolog
chrX_-_71933888 6.62 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
PHKA1
phosphorylase kinase, alpha 1 (muscle)
chr19_-_49576198 6.58 ENST00000221444.1
KCNA7
potassium voltage-gated channel, shaker-related subfamily, member 7
chr7_+_95115210 6.55 ENST00000428113.1
ENST00000325885.5
ASB4
ankyrin repeat and SOCS box containing 4
chr14_-_62217779 6.40 ENST00000554254.1
HIF1A-AS2
HIF1A antisense RNA 2
chr8_-_17533838 6.35 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr14_-_21493123 6.32 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
NDRG family member 2
chr3_+_35721182 6.29 ENST00000413378.1
ENST00000417925.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr7_+_15728003 6.20 ENST00000442176.1
AC005550.4
AC005550.4
chr3_+_35680339 6.20 ENST00000450234.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr1_-_23751189 6.13 ENST00000374601.3
ENST00000450454.2
TCEA3
transcription elongation factor A (SII), 3

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2D_MEF2A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
48.9 195.6 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
17.9 143.0 GO:0035995 detection of muscle stretch(GO:0035995)
10.8 108.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
9.2 36.8 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
9.2 27.6 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
8.7 43.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
8.1 40.7 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
7.3 58.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
6.1 24.5 GO:0005986 sucrose biosynthetic process(GO:0005986)
5.4 472.1 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
4.1 24.7 GO:0036309 protein localization to M-band(GO:0036309)
3.8 15.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
3.5 10.5 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
3.1 115.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
2.9 23.5 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
2.8 31.1 GO:0071313 cellular response to caffeine(GO:0071313)
2.8 19.6 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
2.6 18.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
2.3 11.7 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
2.3 34.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
2.2 60.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
2.2 28.8 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
2.1 23.1 GO:0032264 IMP salvage(GO:0032264)
2.0 26.3 GO:0060297 regulation of sarcomere organization(GO:0060297)
1.9 23.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
1.9 13.5 GO:0055129 L-proline biosynthetic process(GO:0055129)
1.8 11.0 GO:0015853 adenine transport(GO:0015853)
1.8 32.9 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.8 20.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
1.8 7.2 GO:1903028 positive regulation of opsonization(GO:1903028)
1.7 17.0 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.7 10.0 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
1.6 9.8 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
1.6 31.1 GO:0006853 carnitine shuttle(GO:0006853)
1.4 4.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
1.4 60.9 GO:0045214 sarcomere organization(GO:0045214)
1.3 17.4 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
1.3 3.9 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
1.3 3.8 GO:0032242 regulation of nucleoside transport(GO:0032242)
1.2 38.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.1 9.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.1 5.6 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
1.0 23.3 GO:0016540 protein autoprocessing(GO:0016540)
0.9 5.7 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.9 2.8 GO:0033058 directional locomotion(GO:0033058)
0.9 36.1 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.9 18.3 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.9 11.8 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128)
0.9 8.1 GO:0015793 glycerol transport(GO:0015793)
0.9 8.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.9 2.7 GO:0006059 hexitol metabolic process(GO:0006059)
0.9 12.5 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.9 59.4 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.9 101.1 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.8 26.9 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.8 13.8 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.7 6.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.7 4.9 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.7 97.7 GO:0005977 glycogen metabolic process(GO:0005977)
0.7 26.3 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.6 2.5 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.6 2.4 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.6 1.7 GO:0090108 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.6 2.8 GO:0015862 uridine transport(GO:0015862)
0.6 3.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.6 3.9 GO:0051012 microtubule sliding(GO:0051012)
0.5 20.3 GO:0061718 NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.5 6.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.5 5.4 GO:0006013 mannose metabolic process(GO:0006013)
0.5 1.9 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
0.5 1.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.5 7.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.4 21.1 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.4 5.3 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.4 1.3 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.4 1.3 GO:0002188 translation reinitiation(GO:0002188)
0.4 60.7 GO:0006941 striated muscle contraction(GO:0006941)
0.4 26.7 GO:0010107 potassium ion import(GO:0010107)
0.4 4.6 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.4 16.3 GO:0030239 myofibril assembly(GO:0030239)
0.4 4.1 GO:0048664 neuron fate determination(GO:0048664)
0.4 0.8 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.4 3.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.4 1.6 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.4 0.7 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.4 4.6 GO:0042118 endothelial cell activation(GO:0042118)
0.4 1.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.4 2.8 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.3 5.9 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 1.0 GO:0033594 response to hydroxyisoflavone(GO:0033594)
0.3 12.3 GO:0070207 protein homotrimerization(GO:0070207)
0.3 7.5 GO:0003334 keratinocyte development(GO:0003334)
0.3 1.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.3 1.9 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.3 3.5 GO:0097106 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) postsynaptic density organization(GO:0097106) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.3 2.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.3 1.3 GO:0003094 glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.3 211.5 GO:0043687 post-translational protein modification(GO:0043687)
0.3 12.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.3 18.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.3 1.5 GO:0007512 adult heart development(GO:0007512)
0.3 3.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.3 56.8 GO:0034605 cellular response to heat(GO:0034605)
0.2 7.0 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.2 1.5 GO:0006574 valine catabolic process(GO:0006574)
0.2 4.9 GO:0019532 oxalate transport(GO:0019532)
0.2 2.6 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 12.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 3.6 GO:0000733 DNA strand renaturation(GO:0000733)
0.2 16.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 1.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 2.6 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 16.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.2 3.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 1.8 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.2 2.4 GO:0030497 fatty acid elongation(GO:0030497)
0.2 4.8 GO:0007520 myoblast fusion(GO:0007520)
0.2 2.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 4.5 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.1 33.0 GO:0006936 muscle contraction(GO:0006936)
0.1 35.9 GO:0006986 response to unfolded protein(GO:0006986)
0.1 16.9 GO:0032091 negative regulation of protein binding(GO:0032091)
0.1 17.7 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 18.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 1.7 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 9.2 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 0.5 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 14.3 GO:0048738 cardiac muscle tissue development(GO:0048738)
0.1 1.8 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 3.4 GO:0019054 modulation by virus of host process(GO:0019054)
0.1 0.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 2.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 1.0 GO:0060347 heart trabecula formation(GO:0060347)
0.1 0.1 GO:0070252 actin-mediated cell contraction(GO:0070252)
0.1 0.8 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.1 15.2 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 0.6 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 4.0 GO:0019228 neuronal action potential(GO:0019228)
0.1 2.8 GO:0048265 response to pain(GO:0048265)
0.1 0.7 GO:0030222 eosinophil differentiation(GO:0030222)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 1.2 GO:0046415 urate metabolic process(GO:0046415)
0.1 2.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 1.0 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 3.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 3.6 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.4 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 2.7 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.1 4.0 GO:0035329 hippo signaling(GO:0035329)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 5.1 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.4 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 6.8 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 2.4 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 5.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.9 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 2.5 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 12.3 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.9 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 1.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 2.3 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 2.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.9 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 3.3 GO:0015918 sterol transport(GO:0015918)
0.0 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 2.7 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.0 2.0 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 16.0 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.0 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.5 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 1.0 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.7 GO:0048593 camera-type eye morphogenesis(GO:0048593)
0.0 0.3 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
17.7 283.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
17.1 102.6 GO:0005927 muscle tendon junction(GO:0005927)
14.6 58.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
9.8 236.0 GO:0005861 troponin complex(GO:0005861)
6.8 291.5 GO:0005859 muscle myosin complex(GO:0005859)
4.7 60.8 GO:0097512 cardiac myofibril(GO:0097512)
3.8 162.8 GO:0031430 M band(GO:0031430)
3.6 28.8 GO:0005916 fascia adherens(GO:0005916)
3.5 28.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
3.4 60.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
2.9 20.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
2.1 19.3 GO:0032593 insulin-responsive compartment(GO:0032593)
2.0 503.5 GO:0031674 I band(GO:0031674)
1.9 30.3 GO:0016461 unconventional myosin complex(GO:0016461)
1.8 51.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.5 23.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
1.4 14.3 GO:0016012 sarcoglycan complex(GO:0016012)
1.4 6.8 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
1.1 28.7 GO:0032591 dendritic spine membrane(GO:0032591)
1.0 49.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.8 14.0 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.7 47.8 GO:0031941 filamentous actin(GO:0031941)
0.7 18.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.7 4.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.7 6.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.7 6.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.6 2.5 GO:0031592 centrosomal corona(GO:0031592)
0.6 10.6 GO:0031010 ISWI-type complex(GO:0031010)
0.5 2.7 GO:0097454 Schwann cell microvillus(GO:0097454)
0.5 1.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.5 1.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.5 53.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.4 1.3 GO:0043614 multi-eIF complex(GO:0043614)
0.4 1.3 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.4 19.0 GO:0016528 sarcoplasm(GO:0016528)
0.4 5.6 GO:0032039 integrator complex(GO:0032039)
0.4 12.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3 1.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.3 14.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 114.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.3 5.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 0.5 GO:0019898 extrinsic component of membrane(GO:0019898)
0.2 7.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 33.9 GO:0042383 sarcolemma(GO:0042383)
0.2 7.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 10.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 1.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 35.2 GO:0016605 PML body(GO:0016605)
0.2 6.8 GO:0030673 axolemma(GO:0030673)
0.1 3.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 2.4 GO:0001891 phagocytic cup(GO:0001891)
0.1 11.5 GO:0034707 chloride channel complex(GO:0034707)
0.1 2.8 GO:0005922 connexon complex(GO:0005922)
0.1 5.3 GO:0016459 myosin complex(GO:0016459)
0.1 22.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 3.4 GO:0030686 90S preribosome(GO:0030686)
0.1 0.8 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 20.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 6.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 2.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.7 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 9.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 3.5 GO:1904115 axon cytoplasm(GO:1904115)
0.0 3.4 GO:0005771 multivesicular body(GO:0005771)
0.0 1.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 10.0 GO:0043209 myelin sheath(GO:0043209)
0.0 8.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 5.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 20.6 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 11.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 3.4 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 3.9 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 9.2 GO:0005730 nucleolus(GO:0005730)
0.0 2.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 4.3 GO:0030426 growth cone(GO:0030426)
0.0 4.3 GO:0005938 cell cortex(GO:0005938)
0.0 4.9 GO:0070062 extracellular exosome(GO:0070062)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
18.0 71.9 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
15.5 93.0 GO:0051373 FATZ binding(GO:0051373)
12.1 72.8 GO:0031433 telethonin binding(GO:0031433)
9.6 38.4 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
9.2 342.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
7.0 28.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
6.1 24.5 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
6.0 84.4 GO:0031014 troponin T binding(GO:0031014)
5.0 94.4 GO:0032036 myosin heavy chain binding(GO:0032036)
4.6 91.2 GO:0031432 titin binding(GO:0031432)
4.0 32.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
3.9 11.7 GO:0070538 oleic acid binding(GO:0070538)
3.8 34.6 GO:0017018 myosin phosphatase activity(GO:0017018)
3.8 15.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
3.0 6.1 GO:0030172 troponin C binding(GO:0030172)
2.9 23.3 GO:0098821 BMP receptor activity(GO:0098821)
2.9 34.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.7 11.0 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
2.7 21.2 GO:0050682 AF-2 domain binding(GO:0050682)
2.3 50.8 GO:0005344 oxygen transporter activity(GO:0005344)
2.3 20.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
2.2 13.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
2.2 28.8 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
1.9 17.0 GO:0004126 cytidine deaminase activity(GO:0004126)
1.7 59.4 GO:0051393 alpha-actinin binding(GO:0051393)
1.7 60.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.6 9.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
1.6 14.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
1.4 4.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
1.4 27.6 GO:1990239 steroid hormone binding(GO:1990239)
1.4 6.8 GO:0015254 glycerol channel activity(GO:0015254)
1.3 10.5 GO:1904288 BAT3 complex binding(GO:1904288)
1.2 12.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.2 103.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
1.2 20.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
1.2 8.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
1.1 103.2 GO:0008307 structural constituent of muscle(GO:0008307)
1.1 5.4 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
1.1 5.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.9 27.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.9 18.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.8 6.8 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.8 14.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.8 3.8 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.7 187.8 GO:0044325 ion channel binding(GO:0044325)
0.7 6.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.6 2.5 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.6 17.4 GO:0044548 S100 protein binding(GO:0044548)
0.6 2.4 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.6 2.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.6 1.7 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.6 9.7 GO:0042805 actinin binding(GO:0042805)
0.5 3.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.5 27.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.5 2.4 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.5 11.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.5 9.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.5 8.6 GO:0005523 tropomyosin binding(GO:0005523)
0.4 12.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.4 1.3 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.4 27.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 267.5 GO:0003779 actin binding(GO:0003779)
0.3 16.0 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.3 242.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.3 78.2 GO:0005516 calmodulin binding(GO:0005516)
0.3 1.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.3 3.6 GO:0036310 annealing helicase activity(GO:0036310)
0.3 5.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 3.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 2.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 1.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.3 4.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.3 2.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.3 1.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.3 0.8 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 4.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 2.5 GO:0043515 kinetochore binding(GO:0043515)
0.2 12.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 19.2 GO:0070888 E-box binding(GO:0070888)
0.2 13.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 1.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 3.6 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.2 5.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 0.6 GO:0031013 troponin I binding(GO:0031013)
0.2 4.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 22.8 GO:0001618 virus receptor activity(GO:0001618)
0.2 10.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 2.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 2.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 0.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 5.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.2 1.9 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.2 4.0 GO:0071837 HMG box domain binding(GO:0071837)
0.1 18.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 4.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 14.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 7.9 GO:0043022 ribosome binding(GO:0043022)
0.1 1.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 8.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 5.7 GO:0050681 androgen receptor binding(GO:0050681)
0.1 3.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 21.6 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 3.3 GO:0015248 sterol transporter activity(GO:0015248)
0.1 2.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 5.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.4 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 2.8 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.3 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.1 1.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.3 GO:0042923 neuropeptide binding(GO:0042923)
0.1 1.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 5.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 5.4 GO:0005178 integrin binding(GO:0005178)
0.0 1.4 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 4.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.3 GO:0017022 myosin binding(GO:0017022)
0.0 1.2 GO:0022832 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0 3.7 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.3 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.6 GO:0016788 hydrolase activity, acting on ester bonds(GO:0016788)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.2 GO:0002039 p53 binding(GO:0002039)
0.0 2.2 GO:0002020 protease binding(GO:0002020)
0.0 5.0 GO:0008017 microtubule binding(GO:0008017)
0.0 2.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 51.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
1.0 58.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.4 21.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 26.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 11.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 20.4 PID BMP PATHWAY BMP receptor signaling
0.2 24.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 26.9 PID FGF PATHWAY FGF signaling pathway
0.2 3.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.2 13.9 PID CMYB PATHWAY C-MYB transcription factor network
0.1 6.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 3.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 4.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 9.4 PID AURORA B PATHWAY Aurora B signaling
0.1 15.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 5.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 4.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 13.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 3.3 PID IFNG PATHWAY IFN-gamma pathway
0.1 3.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 2.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 3.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 4.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 473.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.4 62.9 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
1.1 83.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
1.0 17.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.8 23.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.7 11.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.6 18.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.5 31.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.5 8.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.4 29.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.4 13.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 23.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.3 96.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.3 1.8 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 18.6 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.2 6.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 9.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 3.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 8.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 10.4 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.2 7.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 7.0 REACTOME DEFENSINS Genes involved in Defensins
0.1 13.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 3.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 5.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 3.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 6.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 3.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 3.7 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1 1.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 3.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 4.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 3.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 9.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.2 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 2.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)