ISMARA results: MIXL1_GSX1_BSX_MEOX2

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Illumina Body Map 2, young vs old

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Results for MIXL1_GSX1_BSX_MEOX2_LHX4

Z-value: 1.14

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Transcription factors associated with MIXL1_GSX1_BSX_MEOX2_LHX4

Gene Symbol	Gene ID	Gene Info
MIXL1 Ensembl NCBI GeneCards UniProt	ENSG00000185155.7	Mix paired-like homeobox
GSX1 Ensembl NCBI GeneCards UniProt	ENSG00000169840.4	GS homeobox 1
BSX Ensembl NCBI GeneCards UniProt	ENSG00000188909.4	brain specific homeobox
MEOX2 Ensembl NCBI GeneCards UniProt	ENSG00000106511.5	mesenchyme homeobox 2
LHX4 Ensembl NCBI GeneCards UniProt	ENSG00000121454.4	LIM homeobox 4

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
LHX4	hg19_v2_chr1_+_180199393_180199426	-0.47	6.2e-03	Click!
GSX1	hg19_v2_chr13_+_28366780_28366780	-0.38	3.0e-02	Click!
BSX	hg19_v2_chr11_-_122852428_122852549	-0.37	4.0e-02	Click!
MEOX2	hg19_v2_chr7_-_15726296_15726437	-0.32	7.5e-02	Click!
MIXL1	hg19_v2_chr1_+_226411319_226411366	-0.19	3.1e-01	Click!

Activity profile of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Sorted Z-values of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_-_36245561 Show fit	8.36	ENST00000506189.1	ARAP2 Ensembl NCBI GeneCards UniProt Show fit	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_-_32157947 Show fit	7.76	ENST00000375050.4	PBX2 Ensembl NCBI GeneCards UniProt Show fit	pre-B-cell leukemia homeobox 2
chr13_-_46716969 Show fit	7.33	ENST00000435666.2	LCP1 Ensembl NCBI GeneCards UniProt Show fit	lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_108541545 Show fit	6.59	ENST00000295756.6	TRAT1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor associated transmembrane adaptor 1
chr14_+_22337014 Show fit	6.55	ENST00000390436.2	TRAV13-1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 13-1
chrX_+_135730297 Show fit	6.46	ENST00000370629.2	CD40LG Ensembl NCBI GeneCards UniProt Show fit	CD40 ligand
chr12_+_8666126 Show fit	6.00	ENST00000299665.2	CLEC4D Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 4, member D
chr3_+_108541608 Show fit	5.50	ENST00000426646.1	TRAT1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor associated transmembrane adaptor 1
chr15_+_58430368 Show fit	5.13	ENST00000558772.1 ENST00000219919.4	AQP9 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 9
chr2_-_158300556 Show fit	5.05	ENST00000264192.3	CYTIP Ensembl NCBI GeneCards UniProt Show fit	cytohesin 1 interacting protein
chr14_+_22739823 Show fit	4.90	ENST00000390464.2	TRAV38-1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 38-1
chr15_+_58430567 Show fit	4.84	ENST00000536493.1	AQP9 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 9
chr4_+_40198527 Show fit	4.74	ENST00000381799.5	RHOH Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member H
chr7_+_142378566 Show fit	4.71	ENST00000390398.3	TRBV25-1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 25-1
chr2_+_169926047 Show fit	4.68	ENST00000428522.1 ENST00000450153.1 ENST00000421653.1	DHRS9 Ensembl NCBI GeneCards UniProt Show fit	dehydrogenase/reductase (SDR family) member 9
chr11_-_2323089 Show fit	4.65	ENST00000456145.2	C11orf21 Ensembl NCBI GeneCards UniProt Show fit	chromosome 11 open reading frame 21
chr5_+_66300464 Show fit	4.62	ENST00000436277.1	MAST4 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated serine/threonine kinase family member 4
chr2_-_89161432 Show fit	4.59	ENST00000390242.2	IGKJ1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa joining 1
chr7_+_80255472 Show fit	4.47	ENST00000428497.1	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule (thrombospondin receptor)
chr2_+_90248739 Show fit	4.33	ENST00000468879.1	IGKV1D-43 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-43
chr2_+_7865923 Show fit	4.27	ENST00000417930.1	AC092580.4 Ensembl NCBI GeneCards UniProt Show fit	AC092580.4
chr12_+_10124110 Show fit	4.25	ENST00000350667.4	CLEC12A Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 12, member A
chr13_-_41593425 Show fit	4.24	ENST00000239882.3	ELF1 Ensembl NCBI GeneCards UniProt Show fit	E74-like factor 1 (ets domain transcription factor)
chr1_-_183538319 Show fit	4.12	ENST00000420553.1 ENST00000419402.1	NCF2 Ensembl NCBI GeneCards UniProt Show fit	neutrophil cytosolic factor 2
chrX_-_21676442 Show fit	4.07	ENST00000379499.2	KLHL34 Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 34
chr1_+_101003687 Show fit	3.99	ENST00000315033.4	GPR88 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 88
chr7_+_50348268 Show fit	3.87	ENST00000438033.1 ENST00000439701.1	IKZF1 Ensembl NCBI GeneCards UniProt Show fit	IKAROS family zinc finger 1 (Ikaros)
chr7_-_92777606 Show fit	3.87	ENST00000437805.1 ENST00000446959.1 ENST00000439952.1 ENST00000414791.1 ENST00000446033.1 ENST00000411955.1 ENST00000318238.4	SAMD9L Ensembl NCBI GeneCards UniProt Show fit	sterile alpha motif domain containing 9-like
chr14_+_22564294 Show fit	3.84	ENST00000390452.2	TRDV1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor delta variable 1
chr14_+_22992573 Show fit	3.67	ENST00000390516.1	TRAJ21 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha joining 21
chr6_-_32908792 Show fit	3.63	ENST00000418107.2	HLA-DMB Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DM beta
chr6_-_116866773 Show fit	3.63	ENST00000368602.3	TRAPPC3L Ensembl NCBI GeneCards UniProt Show fit	trafficking protein particle complex 3-like
chr13_-_99910673 Show fit	3.58	ENST00000397473.2 ENST00000397470.2	GPR18 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 18
chrX_+_135730373 Show fit	3.46	ENST00000370628.2	CD40LG Ensembl NCBI GeneCards UniProt Show fit	CD40 ligand
chr7_+_77428066 Show fit	3.39	ENST00000422959.2 ENST00000307305.8 ENST00000424760.1	PHTF2 Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 2
chr12_-_10151773 Show fit	3.32	ENST00000298527.6 ENST00000348658.4	CLEC1B Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 1, member B
chr1_+_174844645 Show fit	3.31	ENST00000486220.1	RABGAP1L Ensembl NCBI GeneCards UniProt Show fit	RAB GTPase activating protein 1-like
chr6_-_139613269 Show fit	3.31	ENST00000358430.3	TXLNB Ensembl NCBI GeneCards UniProt Show fit	taxilin beta
chr17_-_57229155 Show fit	3.30	ENST00000584089.1	SKA2 Ensembl NCBI GeneCards UniProt Show fit	spindle and kinetochore associated complex subunit 2
chr14_+_22631122 Show fit	3.23	ENST00000390458.3	TRAV29DV5 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene)
chr7_+_37723336 Show fit	3.22	ENST00000450180.1	GPR141 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 141
chr1_-_92952433 Show fit	3.22	ENST00000294702.5	GFI1 Ensembl NCBI GeneCards UniProt Show fit	growth factor independent 1 transcription repressor
chr4_+_40201954 Show fit	3.09	ENST00000511121.1	RHOH Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member H
chr1_-_150738261 Show fit	3.03	ENST00000448301.2 ENST00000368985.3	CTSS Ensembl NCBI GeneCards UniProt Show fit	cathepsin S
chr16_-_4852915 Show fit	2.97	ENST00000322048.7	ROGDI Ensembl NCBI GeneCards UniProt Show fit	rogdi homolog (Drosophila)
chr15_+_75080883 Show fit	2.96	ENST00000567571.1	CSK Ensembl NCBI GeneCards UniProt Show fit	c-src tyrosine kinase
chr12_+_28410128 Show fit	2.88	ENST00000381259.1 ENST00000381256.1	CCDC91 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 91
chr3_-_39321512 Show fit	2.82	ENST00000399220.2	CX3CR1 Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-X3-C motif) receptor 1
chr18_-_3220106 Show fit	2.80	ENST00000356443.4 ENST00000400569.3	MYOM1 Ensembl NCBI GeneCards UniProt Show fit	myomesin 1
chr5_+_137722255 Show fit	2.78	ENST00000542866.1	KDM3B Ensembl NCBI GeneCards UniProt Show fit	lysine (K)-specific demethylase 3B
chr3_-_27764190 Show fit	2.77	ENST00000537516.1	EOMES Ensembl NCBI GeneCards UniProt Show fit	eomesodermin
chr2_+_204571375 Show fit	2.77	ENST00000374478.4	CD28 Ensembl NCBI GeneCards UniProt Show fit	CD28 molecule
chrX_-_19817869 Show fit	2.74	ENST00000379698.4	SH3KBP1 Ensembl NCBI GeneCards UniProt Show fit	SH3-domain kinase binding protein 1
chr18_+_32556892 Show fit	2.74	ENST00000591734.1 ENST00000413393.1 ENST00000589180.1 ENST00000587359.1	MAPRE2 Ensembl NCBI GeneCards UniProt Show fit	microtubule-associated protein, RP/EB family, member 2
chr6_-_66417107 Show fit	2.70	ENST00000370621.3 ENST00000370618.3 ENST00000503581.1 ENST00000393380.2	EYS Ensembl NCBI GeneCards UniProt Show fit	eyes shut homolog (Drosophila)
chr7_+_77428149 Show fit	2.69	ENST00000415251.2 ENST00000275575.7	PHTF2 Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 2
chr17_-_9694614 Show fit	2.67	ENST00000330255.5 ENST00000571134.1	DHRS7C Ensembl NCBI GeneCards UniProt Show fit	dehydrogenase/reductase (SDR family) member 7C
chr4_+_36283213 Show fit	2.66	ENST00000357504.3	DTHD1 Ensembl NCBI GeneCards UniProt Show fit	death domain containing 1
chr17_-_38956205 Show fit	2.61	ENST00000306658.7	KRT28 Ensembl NCBI GeneCards UniProt Show fit	keratin 28
chr14_+_92789498 Show fit	2.61	ENST00000531433.1	SLC24A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr2_-_145277569 Show fit	2.58	ENST00000303660.4	ZEB2 Ensembl NCBI GeneCards UniProt Show fit	zinc finger E-box binding homeobox 2
chr18_-_3219847 Show fit	2.58	ENST00000261606.7	MYOM1 Ensembl NCBI GeneCards UniProt Show fit	myomesin 1
chr1_+_154401791 Show fit	2.57	ENST00000476006.1	IL6R Ensembl NCBI GeneCards UniProt Show fit	interleukin 6 receptor
chr7_+_18329712 Show fit	2.56	ENST00000433709.2	HDAC9 Ensembl NCBI GeneCards UniProt Show fit	histone deacetylase 9
chr2_-_61697862 Show fit	2.55	ENST00000398571.2	USP34 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 34
chr1_+_62439037 Show fit	2.48	ENST00000545929.1	INADL Ensembl NCBI GeneCards UniProt Show fit	InaD-like (Drosophila)
chr2_-_145188137 Show fit	2.47	ENST00000440875.1	ZEB2 Ensembl NCBI GeneCards UniProt Show fit	zinc finger E-box binding homeobox 2
chr14_+_22947861 Show fit	2.47	ENST00000390482.1	TRAJ57 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha joining 57
chr6_-_32908765 Show fit	2.46	ENST00000416244.2	HLA-DMB Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DM beta
chrX_+_123097014 Show fit	2.41	ENST00000394478.1	STAG2 Ensembl NCBI GeneCards UniProt Show fit	stromal antigen 2
chr5_+_66300446 Show fit	2.41	ENST00000261569.7	MAST4 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated serine/threonine kinase family member 4
chr19_+_50016610 Show fit	2.41	ENST00000596975.1	FCGRT Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG, receptor, transporter, alpha
chr1_+_117544366 Show fit	2.39	ENST00000256652.4 ENST00000369470.1	CD101 Ensembl NCBI GeneCards UniProt Show fit	CD101 molecule
chr2_+_68962014 Show fit	2.38	ENST00000467265.1	ARHGAP25 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 25
chr15_+_86087267 Show fit	2.36	ENST00000558166.1	AKAP13 Ensembl NCBI GeneCards UniProt Show fit	A kinase (PRKA) anchor protein 13
chr2_-_214016314 Show fit	2.36	ENST00000434687.1 ENST00000374319.4	IKZF2 Ensembl NCBI GeneCards UniProt Show fit	IKAROS family zinc finger 2 (Helios)
chr18_-_44181442 Show fit	2.32	ENST00000398722.4	LOXHD1 Ensembl NCBI GeneCards UniProt Show fit	lipoxygenase homology domains 1
chr6_+_53964336 Show fit	2.32	ENST00000447836.2 ENST00000511678.1	MLIP Ensembl NCBI GeneCards UniProt Show fit	muscular LMNA-interacting protein
chr11_-_111649015 Show fit	2.30	ENST00000529841.1	RP11-108O10.2 Ensembl NCBI GeneCards UniProt Show fit	RP11-108O10.2
chr13_+_78315466 Show fit	2.30	ENST00000314070.5 ENST00000462234.1	SLAIN1 Ensembl NCBI GeneCards UniProt Show fit	SLAIN motif family, member 1
chr2_+_90273679 Show fit	2.29	ENST00000423080.2	IGKV3D-7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-7
chr2_+_68961934 Show fit	2.29	ENST00000409202.3	ARHGAP25 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 25
chrX_-_15332665 Show fit	2.28	ENST00000537676.1 ENST00000344384.4	ASB11 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and SOCS box containing 11
chr11_-_33913708 Show fit	2.27	ENST00000257818.2	LMO2 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 2 (rhombotin-like 1)
chr11_-_104972158 Show fit	2.27	ENST00000598974.1 ENST00000593315.1 ENST00000594519.1 ENST00000415981.2 ENST00000525374.1 ENST00000375707.1	CASP1 Ensembl NCBI GeneCards UniProt Show fit CARD16 Ensembl NCBI GeneCards UniProt Show fit CARD17 Ensembl NCBI GeneCards UniProt Show fit	caspase 1, apoptosis-related cysteine peptidase caspase recruitment domain family, member 16 caspase recruitment domain family, member 17
chr16_+_53133070 Show fit	2.26	ENST00000565832.1	CHD9 Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 9
chr7_-_77427676 Show fit	2.24	ENST00000257663.3	TMEM60 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 60
chr7_-_28220354 Show fit	2.24	ENST00000283928.5	JAZF1 Ensembl NCBI GeneCards UniProt Show fit	JAZF zinc finger 1
chr6_+_26365443 Show fit	2.24	ENST00000527422.1 ENST00000356386.2 ENST00000396934.3 ENST00000377708.2 ENST00000396948.1 ENST00000508906.2	BTN3A2 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin, subfamily 3, member A2
chr14_+_22931924 Show fit	2.23	ENST00000390477.2	TRDC Ensembl NCBI GeneCards UniProt Show fit	T cell receptor delta constant
chr3_+_121774202 Show fit	2.23	ENST00000469710.1 ENST00000493101.1 ENST00000330540.2 ENST00000264468.5	CD86 Ensembl NCBI GeneCards UniProt Show fit	CD86 molecule
chr5_-_142780280 Show fit	2.22	ENST00000424646.2	NR3C1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr3_-_33686925 Show fit	2.22	ENST00000485378.2 ENST00000313350.6 ENST00000487200.1	CLASP2 Ensembl NCBI GeneCards UniProt Show fit	cytoplasmic linker associated protein 2
chr2_+_68961905 Show fit	2.18	ENST00000295381.3	ARHGAP25 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 25
chr2_-_179659669 Show fit	2.15	ENST00000436599.1	TTN Ensembl NCBI GeneCards UniProt Show fit	titin
chr2_+_17997763 Show fit	2.15	ENST00000281047.3	MSGN1 Ensembl NCBI GeneCards UniProt Show fit	mesogenin 1
chr4_+_169013666 Show fit	2.14	ENST00000359299.3	ANXA10 Ensembl NCBI GeneCards UniProt Show fit	annexin A10
chr7_+_115862858 Show fit	2.14	ENST00000393481.2	TES Ensembl NCBI GeneCards UniProt Show fit	testis derived transcript (3 LIM domains)
chr21_-_32253874 Show fit	2.14	ENST00000332378.4	KRTAP11-1 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 11-1
chr1_+_111415757 Show fit	2.13	ENST00000429072.2 ENST00000271324.5	CD53 Ensembl NCBI GeneCards UniProt Show fit	CD53 molecule
chr13_-_99910620 Show fit	2.10	ENST00000416594.1	GPR18 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 18
chr2_-_89160770 Show fit	2.09	ENST00000390240.2	IGKJ3 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa joining 3
chr1_-_232651312 Show fit	2.07	ENST00000262861.4	SIPA1L2 Ensembl NCBI GeneCards UniProt Show fit	signal-induced proliferation-associated 1 like 2
chr4_-_70653673 Show fit	2.06	ENST00000512870.1	SULT1B1 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family, cytosolic, 1B, member 1
chr14_+_22465771 Show fit	2.05	ENST00000390445.2	TRAV17 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 17
chr1_+_198607801 Show fit	2.03	ENST00000367379.1	PTPRC Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase, receptor type, C
chr17_-_39191107 Show fit	2.03	ENST00000344363.5	KRTAP1-3 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 1-3
chr3_-_69129501 Show fit	2.01	ENST00000540295.1 ENST00000415609.2 ENST00000361055.4 ENST00000349511.4	UBA3 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-like modifier activating enzyme 3
chr10_-_104866395 Show fit	2.01	ENST00000458345.1	NT5C2 Ensembl NCBI GeneCards UniProt Show fit	5'-nucleotidase, cytosolic II
chr4_-_48116540 Show fit	2.01	ENST00000506073.1	TXK Ensembl NCBI GeneCards UniProt Show fit	TXK tyrosine kinase
chr13_+_78315348 Show fit	2.00	ENST00000441784.1	SLAIN1 Ensembl NCBI GeneCards UniProt Show fit	SLAIN motif family, member 1
chr17_-_72527605 Show fit	1.98	ENST00000392621.1 ENST00000314401.3	CD300LB Ensembl NCBI GeneCards UniProt Show fit	CD300 molecule-like family member b
chr11_+_35222629 Show fit	1.97	ENST00000526553.1	CD44 Ensembl NCBI GeneCards UniProt Show fit	CD44 molecule (Indian blood group)
chr6_-_130182410 Show fit	1.95	ENST00000368143.1	TMEM244 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 244
chr2_+_90211643 Show fit	1.95	ENST00000390277.2	IGKV3D-11 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-11
chr11_-_104905840 Show fit	1.93	ENST00000526568.1 ENST00000393136.4 ENST00000531166.1 ENST00000534497.1 ENST00000527979.1 ENST00000446369.1 ENST00000353247.5 ENST00000528974.1 ENST00000533400.1 ENST00000525825.1 ENST00000436863.3	CASP1 Ensembl NCBI GeneCards UniProt Show fit	caspase 1, apoptosis-related cysteine peptidase
chr6_+_130339710 Show fit	1.92	ENST00000526087.1 ENST00000533560.1 ENST00000361794.2	L3MBTL3 Ensembl NCBI GeneCards UniProt Show fit	l(3)mbt-like 3 (Drosophila)
chr2_-_89161064 Show fit	1.91	ENST00000390241.2	IGKJ2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa joining 2
chr12_-_114841703 Show fit	1.91	ENST00000526441.1	TBX5 Ensembl NCBI GeneCards UniProt Show fit	T-box 5
chr14_+_23001452 Show fit	1.90	ENST00000390526.1	TRAJ11 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha joining 11
chr10_+_126630692 Show fit	1.89	ENST00000359653.4	ZRANB1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, RAN-binding domain containing 1
chr3_-_33686743 Show fit	1.88	ENST00000333778.6 ENST00000539981.1	CLASP2 Ensembl NCBI GeneCards UniProt Show fit	cytoplasmic linker associated protein 2
chr5_+_54398463 Show fit	1.88	ENST00000274306.6	GZMA Ensembl NCBI GeneCards UniProt Show fit	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr5_+_53751445 Show fit	1.87	ENST00000302005.1	HSPB3 Ensembl NCBI GeneCards UniProt Show fit	heat shock 27kDa protein 3
chr2_+_190541153 Show fit	1.84	ENST00000313581.4 ENST00000438402.2 ENST00000431575.2 ENST00000281412.6	ANKAR Ensembl NCBI GeneCards UniProt Show fit	ankyrin and armadillo repeat containing
chr14_+_22670455 Show fit	1.83	ENST00000390460.1	TRAV26-2 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 26-2
chr10_-_92681033 Show fit	1.83	ENST00000371697.3	ANKRD1 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 1 (cardiac muscle)
chr2_-_109605663 Show fit	1.82	ENST00000409271.1 ENST00000258443.2 ENST00000376651.1	EDAR Ensembl NCBI GeneCards UniProt Show fit	ectodysplasin A receptor
chr10_+_69865866 Show fit	1.81	ENST00000354393.2	MYPN Ensembl NCBI GeneCards UniProt Show fit	myopalladin
chr10_-_21186144 Show fit	1.81	ENST00000377119.1	NEBL Ensembl NCBI GeneCards UniProt Show fit	nebulette
chrY_+_14958970 Show fit	1.80	ENST00000453031.1	USP9Y Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 9, Y-linked
chr6_-_116833500 Show fit	1.79	ENST00000356128.4	TRAPPC3L Ensembl NCBI GeneCards UniProt Show fit	trafficking protein particle complex 3-like
chr10_+_94451574 Show fit	1.78	ENST00000492654.2	HHEX Ensembl NCBI GeneCards UniProt Show fit	hematopoietically expressed homeobox
chr3_-_191000172 Show fit	1.78	ENST00000427544.2	UTS2B Ensembl NCBI GeneCards UniProt Show fit	urotensin 2B
chr1_-_157746909 Show fit	1.77	ENST00000392274.3 ENST00000361516.3 ENST00000368181.4	FCRL2 Ensembl NCBI GeneCards UniProt Show fit	Fc receptor-like 2
chr13_+_78315528 Show fit	1.74	ENST00000496045.1	SLAIN1 Ensembl NCBI GeneCards UniProt Show fit	SLAIN motif family, member 1
chr4_-_182186182 Show fit	1.73	ENST00000512547.1	RP11-665C14.2 Ensembl NCBI GeneCards UniProt Show fit	RP11-665C14.2
chr5_+_137673200 Show fit	1.71	ENST00000434981.2	FAM53C Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 53, member C
chr2_-_40680578 Show fit	1.70	ENST00000455476.1	SLC8A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 8 (sodium/calcium exchanger), member 1
chr14_+_22748980 Show fit	1.70	ENST00000390465.2	TRAV38-2DV8 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 38-2/delta variable 8
chr12_-_56694083 Show fit	1.68	ENST00000552688.1 ENST00000548041.1 ENST00000551137.1 ENST00000551968.1 ENST00000542324.2 ENST00000546930.1 ENST00000549221.1 ENST00000550159.1 ENST00000550734.1	CS Ensembl NCBI GeneCards UniProt Show fit	citrate synthase
chr10_-_36812323 Show fit	1.68	ENST00000543053.1	NAMPTL Ensembl NCBI GeneCards UniProt Show fit	nicotinamide phosphoribosyltransferase-like
chr18_+_32173276 Show fit	1.67	ENST00000591816.1 ENST00000588125.1 ENST00000598334.1 ENST00000588684.1 ENST00000554864.3 ENST00000399121.5 ENST00000595022.1 ENST00000269190.7 ENST00000399097.3	DTNA Ensembl NCBI GeneCards UniProt Show fit	dystrobrevin, alpha
chr17_-_39203519 Show fit	1.65	ENST00000542137.1 ENST00000391419.3	KRTAP2-1 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 2-1
chr1_-_25291475 Show fit	1.65	ENST00000338888.3 ENST00000399916.1	RUNX3 Ensembl NCBI GeneCards UniProt Show fit	runt-related transcription factor 3
chr10_-_33405600 Show fit	1.62	ENST00000414308.1	RP11-342D11.3 Ensembl NCBI GeneCards UniProt Show fit	RP11-342D11.3
chr11_+_59824060 Show fit	1.62	ENST00000395032.2 ENST00000358152.2	MS4A3 Ensembl NCBI GeneCards UniProt Show fit	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr2_+_149402989 Show fit	1.61	ENST00000397424.2	EPC2 Ensembl NCBI GeneCards UniProt Show fit	enhancer of polycomb homolog 2 (Drosophila)
chr6_-_25042231 Show fit	1.61	ENST00000510784.2	FAM65B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 65, member B
chr7_+_80253387 Show fit	1.60	ENST00000438020.1	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule (thrombospondin receptor)
chrX_+_37639302 Show fit	1.59	ENST00000545017.1 ENST00000536160.1	CYBB Ensembl NCBI GeneCards UniProt Show fit	cytochrome b-245, beta polypeptide
chrX_+_107288280 Show fit	1.59	ENST00000458383.1	VSIG1 Ensembl NCBI GeneCards UniProt Show fit	V-set and immunoglobulin domain containing 1
chr20_+_42523336 Show fit	1.59	ENST00000428529.1	RP5-1030M6.3 Ensembl NCBI GeneCards UniProt Show fit	RP5-1030M6.3
chr5_-_39219641 Show fit	1.59	ENST00000509072.1 ENST00000504542.1 ENST00000505428.1 ENST00000506557.1	FYB Ensembl NCBI GeneCards UniProt Show fit	FYN binding protein
chr15_+_80351910 Show fit	1.59	ENST00000261749.6 ENST00000561060.1	ZFAND6 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, AN1-type domain 6
chr2_-_89327228 Show fit	1.59	ENST00000483158.1	IGKV3-11 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-11
chr4_-_120243545 Show fit	1.59	ENST00000274024.3	FABP2 Ensembl NCBI GeneCards UniProt Show fit	fatty acid binding protein 2, intestinal
chr12_+_64798826 Show fit	1.58	ENST00000540203.1	XPOT Ensembl NCBI GeneCards UniProt Show fit	exportin, tRNA
chr1_+_74701062 Show fit	1.58	ENST00000326637.3	TNNI3K Ensembl NCBI GeneCards UniProt Show fit	TNNI3 interacting kinase
chr13_+_78315295 Show fit	1.57	ENST00000351546.3	SLAIN1 Ensembl NCBI GeneCards UniProt Show fit	SLAIN motif family, member 1
chr14_+_22615942 Show fit	1.57	ENST00000390457.2	TRAV27 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 27
chr4_+_26324474 Show fit	1.56	ENST00000514675.1	RBPJ Ensembl NCBI GeneCards UniProt Show fit	recombination signal binding protein for immunoglobulin kappa J region
chr14_+_39944025 Show fit	1.55	ENST00000554328.1 ENST00000556620.1 ENST00000557197.1	RP11-111A21.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-111A21.1
chr14_+_22180536 Show fit	1.54	ENST00000390424.2	TRAV2 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 2
chr1_+_81106951 Show fit	1.54	ENST00000443565.1	RP5-887A10.1 Ensembl NCBI GeneCards UniProt Show fit	RP5-887A10.1
chr14_+_22987424 Show fit	1.53	ENST00000390511.1	TRAJ26 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha joining 26
chr6_+_26199737 Show fit	1.51	ENST00000359985.1	HIST1H2BF Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H2bf
chr8_+_28748765 Show fit	1.51	ENST00000355231.5	HMBOX1 Ensembl NCBI GeneCards UniProt Show fit	homeobox containing 1
chr3_-_18480173 Show fit	1.50	ENST00000414509.1	SATB1 Ensembl NCBI GeneCards UniProt Show fit	SATB homeobox 1
chr3_-_18480260 Show fit	1.49	ENST00000454909.2	SATB1 Ensembl NCBI GeneCards UniProt Show fit	SATB homeobox 1
chr4_-_89442940 Show fit	1.49	ENST00000527353.1	PIGY Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol glycan anchor biosynthesis, class Y
chr5_-_150473127 Show fit	1.49	ENST00000521001.1	TNIP1 Ensembl NCBI GeneCards UniProt Show fit	TNFAIP3 interacting protein 1
chr8_+_42873548 Show fit	1.47	ENST00000533338.1 ENST00000534420.1	HOOK3 Ensembl NCBI GeneCards UniProt Show fit RP11-598P20.5 Ensembl NCBI GeneCards UniProt Show fit	hook microtubule-tethering protein 3 Uncharacterized protein
chr18_+_61554932 Show fit	1.46	ENST00000299502.4 ENST00000457692.1 ENST00000413956.1	SERPINB2 Ensembl NCBI GeneCards UniProt Show fit	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr20_-_7238861 Show fit	1.46	ENST00000428954.1	RP11-19D2.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-19D2.1
chr3_-_178103144 Show fit	1.46	ENST00000417383.1 ENST00000418585.1 ENST00000411727.1 ENST00000439810.1	RP11-33A14.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-33A14.1
chr12_-_10605929 Show fit	1.45	ENST00000347831.5 ENST00000359151.3	KLRC1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin-like receptor subfamily C, member 1
chr3_-_141747950 Show fit	1.45	ENST00000497579.1	TFDP2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor Dp-2 (E2F dimerization partner 2)
chr4_+_71384257 Show fit	1.44	ENST00000339336.4	AMTN Ensembl NCBI GeneCards UniProt Show fit	amelotin
chr11_+_59824127 Show fit	1.42	ENST00000278865.3	MS4A3 Ensembl NCBI GeneCards UniProt Show fit	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr3_+_186692745 Show fit	1.42	ENST00000438590.1	ST6GAL1 Ensembl NCBI GeneCards UniProt Show fit	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr6_-_9933500 Show fit	1.42	ENST00000492169.1	OFCC1 Ensembl NCBI GeneCards UniProt Show fit	orofacial cleft 1 candidate 1
chr6_-_32784687 Show fit	1.40	ENST00000447394.1 ENST00000438763.2	HLA-DOB Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DO beta
chr2_+_204571198 Show fit	1.40	ENST00000374481.3 ENST00000458610.2 ENST00000324106.8	CD28 Ensembl NCBI GeneCards UniProt Show fit	CD28 molecule
chr12_-_56693758 Show fit	1.39	ENST00000547298.1 ENST00000551936.1 ENST00000551253.1 ENST00000551473.1	CS Ensembl NCBI GeneCards UniProt Show fit	citrate synthase
chr14_+_22433675 Show fit	1.39	ENST00000390442.3	TRAV12-3 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 12-3
chr15_-_98836406 Show fit	1.39	ENST00000560360.1	CTD-2544M6.1 Ensembl NCBI GeneCards UniProt Show fit	CTD-2544M6.1
chr12_+_56325231 Show fit	1.38	ENST00000549368.1	DGKA Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol kinase, alpha 80kDa
chr14_+_61654271 Show fit	1.38	ENST00000555185.1 ENST00000557294.1 ENST00000556778.1	PRKCH Ensembl NCBI GeneCards UniProt Show fit	protein kinase C, eta
chr9_+_12693336 Show fit	1.37	ENST00000381137.2 ENST00000388918.5	TYRP1 Ensembl NCBI GeneCards UniProt Show fit	tyrosinase-related protein 1
chr19_-_46088068 Show fit	1.37	ENST00000263275.4 ENST00000323060.3	OPA3 Ensembl NCBI GeneCards UniProt Show fit	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr5_-_147286065 Show fit	1.37	ENST00000318315.4 ENST00000515291.1	C5orf46 Ensembl NCBI GeneCards UniProt Show fit	chromosome 5 open reading frame 46
chr4_-_89205705 Show fit	1.36	ENST00000295908.7 ENST00000510548.2 ENST00000508256.1	PPM1K Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr14_+_32798547 Show fit	1.36	ENST00000557354.1 ENST00000557102.1 ENST00000557272.1	AKAP6 Ensembl NCBI GeneCards UniProt Show fit	A kinase (PRKA) anchor protein 6
chr2_+_152214098 Show fit	1.36	ENST00000243347.3	TNFAIP6 Ensembl NCBI GeneCards UniProt Show fit	tumor necrosis factor, alpha-induced protein 6
chr17_-_38911580 Show fit	1.35	ENST00000312150.4	KRT25 Ensembl NCBI GeneCards UniProt Show fit	keratin 25
chr12_+_93096619 Show fit	1.35	ENST00000397833.3	C12orf74 Ensembl NCBI GeneCards UniProt Show fit	chromosome 12 open reading frame 74
chr11_+_59856130 Show fit	1.34	ENST00000278888.3	MS4A2 Ensembl NCBI GeneCards UniProt Show fit	membrane-spanning 4-domains, subfamily A, member 2
chr7_+_107110488 Show fit	1.34	ENST00000304402.4	GPR22 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 22
chr4_-_76928641 Show fit	1.34	ENST00000264888.5	CXCL9 Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-X-C motif) ligand 9

Network of associatons between targets according to the STRING database.

First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	6.1	GO:2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
1.7	10.0	GO:1904823	pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
1.4	12.9	GO:0001920	negative regulation of receptor recycling(GO:0001920)
1.4	5.7	GO:0002304	gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
1.3	3.9	GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.1	3.2	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
1.0	4.2	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.0	3.1	GO:0002416	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
1.0	4.0	GO:0061743	motor learning(GO:0061743)
0.9	2.8	GO:0002881	negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.9	2.7	GO:0070175	positive regulation of enamel mineralization(GO:0070175)
0.8	4.2	GO:2000473	regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.8	7.3	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
0.7	2.2	GO:0002644	negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.7	2.2	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.7	2.0	GO:0007113	endomitotic cell cycle(GO:0007113)
0.6	2.6	GO:0002384	hepatic immune response(GO:0002384)
0.6	1.3	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
0.6	6.4	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.6	1.9	GO:0003218	cardiac left ventricle formation(GO:0003218)
0.6	2.4	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.6	1.8	GO:0061010	negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.5	6.6	GO:2000332	blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.5	3.8	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.5	2.7	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.5	1.9	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
0.5	1.4	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.4	2.6	GO:0002729	positive regulation of natural killer cell cytokine production(GO:0002729)
0.4	4.7	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4	1.3	GO:0002528	regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.4	2.4	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.4	9.9	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.4	1.5	GO:0050883	negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.4	3.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.4	1.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.4	5.5	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.4	2.9	GO:0048769	sarcomerogenesis(GO:0048769)
0.3	1.0	GO:1904897	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.3	4.3	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.3	2.6	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3	8.0	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.3	1.2	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.3	1.5	GO:0044501	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3	2.0	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.3	0.6	GO:0070054	mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.3	1.1	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.3	4.1	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.3	1.1	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.3	1.0	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.2	4.5	GO:0046085	adenosine metabolic process(GO:0046085)
0.2	2.2	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.2	1.0	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.2	1.9	GO:1905066	positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2	1.0	GO:1990737	response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.2	1.2	GO:0035513	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.2	0.9	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.2	0.7	GO:1902997	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2	0.7	GO:1990637	response to prolactin(GO:1990637)
0.2	1.1	GO:0090402	oncogene-induced cell senescence(GO:0090402)
0.2	2.0	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.2	2.0	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2	0.9	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.2	0.6	GO:1904211	membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2	2.7	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.2	1.5	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.2	0.8	GO:0097068	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.2	2.1	GO:0097338	response to clozapine(GO:0097338)
0.2	1.6	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2	1.2	GO:0018032	protein amidation(GO:0018032)
0.2	2.8	GO:0072718	response to cisplatin(GO:0072718)
0.2	0.6	GO:0001694	histamine biosynthetic process(GO:0001694)
0.2	2.9	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.2	0.8	GO:2001023	regulation of response to drug(GO:2001023)
0.2	4.0	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2	1.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.2	0.2	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.2	1.3	GO:0071672	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.2	1.3	GO:0071461	cellular response to redox state(GO:0071461)
0.2	0.6	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
0.2	0.9	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2	5.3	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.2	1.5	GO:1905150	regulation of voltage-gated sodium channel activity(GO:1905150)
0.2	0.5	GO:0006258	UDP-glucose catabolic process(GO:0006258)
0.2	0.2	GO:0003352	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) regulation of microtubule-based movement(GO:0060632)
0.2	0.5	GO:0060345	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.2	1.1	GO:0035063	nuclear speck organization(GO:0035063)
0.2	1.9	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2	0.7	GO:0006480	N-terminal protein amino acid methylation(GO:0006480)
0.2	0.7	GO:0045209	MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.2	0.5	GO:0090467	L-arginine import(GO:0043091) arginine import(GO:0090467)
0.2	0.2	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2	0.7	GO:0019417	sulfur oxidation(GO:0019417)
0.2	2.4	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.2	1.4	GO:0034350	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.2	0.5	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.2	0.5	GO:1905133	metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.2	5.4	GO:0072643	interferon-gamma secretion(GO:0072643)
0.2	3.0	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2	2.0	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.2	0.5	GO:1901876	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.2	5.5	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2	0.6	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.2	0.9	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2	0.3	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.2	0.8	GO:1901545	cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.2	0.8	GO:0061502	uropod organization(GO:0032796) early endosome to recycling endosome transport(GO:0061502)
0.2	5.0	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.2	2.0	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2	1.7	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.2	0.6	GO:0046338	phosphatidylethanolamine catabolic process(GO:0046338)
0.2	0.8	GO:0048496	maintenance of organ identity(GO:0048496)
0.2	0.5	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.2	1.2	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.2	6.8	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	1.0	GO:0003138	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1	0.6	GO:0003292	cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.1	0.3	GO:0048633	positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1	0.8	GO:0010813	neuropeptide catabolic process(GO:0010813) substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1	0.3	GO:0090427	activation of meiosis(GO:0090427)
0.1	0.4	GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1	1.1	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	0.8	GO:0051541	elastin metabolic process(GO:0051541)
0.1	1.6	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.1	0.5	GO:0030821	negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1	0.4	GO:0019230	proprioception(GO:0019230)
0.1	2.4	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1	1.7	GO:0030091	protein repair(GO:0030091)
0.1	0.8	GO:0010752	regulation of cGMP-mediated signaling(GO:0010752)
0.1	1.3	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.1	0.6	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.1	1.1	GO:0070269	pyroptosis(GO:0070269)
0.1	0.4	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
0.1	0.9	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1	2.0	GO:0043249	erythrocyte maturation(GO:0043249)
0.1	0.4	GO:0002194	hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1	3.0	GO:0042832	defense response to protozoan(GO:0042832)
0.1	3.3	GO:0030220	platelet formation(GO:0030220)
0.1	0.6	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.1	0.5	GO:0009236	cobalamin biosynthetic process(GO:0009236)
0.1	0.9	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1	0.5	GO:0036292	DNA rewinding(GO:0036292)
0.1	1.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	0.2	GO:1900365	positive regulation of mRNA polyadenylation(GO:1900365)
0.1	2.2	GO:0007379	segment specification(GO:0007379)
0.1	0.4	GO:1903674	regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1	3.1	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.1	0.3	GO:0006173	dADP biosynthetic process(GO:0006173)
0.1	1.8	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	1.8	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1	0.5	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.7	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.1	0.9	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1	1.2	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.1	2.7	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1	21.2	GO:0002377	immunoglobulin production(GO:0002377)
0.1	0.3	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.1	0.7	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.1	0.5	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
0.1	1.0	GO:0061734	parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.1	0.6	GO:0008343	adult feeding behavior(GO:0008343)
0.1	0.3	GO:0060304	regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.1	0.5	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1	0.7	GO:0051697	protein delipidation(GO:0051697)
0.1	0.3	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.1	0.9	GO:1902952	positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1	0.4	GO:1901846	positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.1	0.9	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.1	0.8	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.6	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.1	2.1	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.1	0.3	GO:1902544	regulation of DNA N-glycosylase activity(GO:1902544)
0.1	7.7	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.1	0.2	GO:0051387	negative regulation of icosanoid secretion(GO:0032304) negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1	1.8	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.1	1.1	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.1	0.5	GO:0001555	oocyte growth(GO:0001555)
0.1	2.8	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1	0.7	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.1	2.7	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.1	0.4	GO:0000354	cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1	0.3	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.6	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1	1.9	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.1	1.5	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1	0.5	GO:0030038	contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1	3.0	GO:0045730	respiratory burst(GO:0045730)
0.1	0.9	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1	1.6	GO:0030207	chondroitin sulfate catabolic process(GO:0030207) dermatan sulfate biosynthetic process(GO:0030208)
0.1	1.4	GO:0060155	platelet dense granule organization(GO:0060155)
0.1	0.8	GO:0071233	cellular response to leucine(GO:0071233)
0.1	8.0	GO:0002292	T cell differentiation involved in immune response(GO:0002292)
0.1	2.7	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	0.2	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.1	1.0	GO:0044539	long-chain fatty acid import(GO:0044539)
0.1	0.2	GO:0032903	viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1	0.3	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.1	0.5	GO:0010650	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	0.6	GO:0071896	protein localization to adherens junction(GO:0071896)
0.1	2.1	GO:0045109	intermediate filament organization(GO:0045109)
0.1	0.6	GO:0036438	maintenance of lens transparency(GO:0036438)
0.1	1.0	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1	1.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	0.3	GO:0030573	bile acid catabolic process(GO:0030573)
0.1	1.8	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.1	0.5	GO:0032740	positive regulation of interleukin-17 production(GO:0032740)
0.1	0.2	GO:1904798	positive regulation of core promoter binding(GO:1904798)
0.1	0.6	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1	0.2	GO:0061582	colon epithelial cell migration(GO:0061580) intestinal epithelial cell migration(GO:0061582)
0.1	0.4	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1	2.3	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.1	0.2	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1	0.1	GO:0061009	common bile duct development(GO:0061009)
0.1	0.1	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1	0.6	GO:0007296	vitellogenesis(GO:0007296)
0.1	0.2	GO:1904562	phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1	0.6	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.1	0.2	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.1	0.1	GO:0022615	protein to membrane docking(GO:0022615)
0.1	0.6	GO:1904970	brush border assembly(GO:1904970)
0.1	1.2	GO:0000338	protein deneddylation(GO:0000338)
0.1	0.4	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	1.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.3	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1	0.6	GO:1903551	regulation of extracellular exosome assembly(GO:1903551)
0.1	0.7	GO:2001300	lipoxin metabolic process(GO:2001300)
0.1	0.3	GO:0000117	regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1	1.1	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.1	0.3	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.1	0.5	GO:1903826	arginine transmembrane transport(GO:1903826)
0.1	0.2	GO:0071418	cellular response to amine stimulus(GO:0071418)
0.1	0.5	GO:0070475	rRNA base methylation(GO:0070475)
0.1	2.2	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.1	0.4	GO:0048733	sebaceous gland development(GO:0048733)
0.1	0.3	GO:0072709	cellular response to sorbitol(GO:0072709)
0.1	1.8	GO:0032098	regulation of appetite(GO:0032098)
0.1	1.0	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.1	4.7	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	0.5	GO:0035690	cellular response to drug(GO:0035690)
0.1	1.6	GO:0086069	bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1	0.2	GO:1904116	response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1	0.4	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.1	0.8	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	0.8	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.8	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.1	0.4	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.1	0.4	GO:0090234	regulation of kinetochore assembly(GO:0090234)
0.1	0.4	GO:0001676	long-chain fatty acid metabolic process(GO:0001676)
0.1	0.2	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.1	0.3	GO:0010157	response to chlorate(GO:0010157)
0.1	0.2	GO:0002399	MHC class II protein complex assembly(GO:0002399)
0.1	0.3	GO:0002767	immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1	0.2	GO:0051598	meiotic recombination checkpoint(GO:0051598)
0.1	0.7	GO:0071600	otic vesicle morphogenesis(GO:0071600)
0.1	0.2	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.1	0.5	GO:0035898	parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.1	0.4	GO:0019236	response to pheromone(GO:0019236)
0.1	0.8	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.1	0.2	GO:1904647	response to rotenone(GO:1904647)
0.1	0.4	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1	0.8	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.1	0.4	GO:0051012	microtubule sliding(GO:0051012)
0.1	1.4	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.1	0.6	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779)
0.1	3.4	GO:0006910	phagocytosis, recognition(GO:0006910)
0.1	2.3	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1	0.1	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1	1.9	GO:0006625	protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1	4.3	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.1	1.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	1.3	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	0.5	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.1	2.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.1	0.6	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0	0.2	GO:1900148	Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.0	0.3	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.2	GO:0051892	negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0	0.6	GO:0010668	ectodermal cell differentiation(GO:0010668)
0.0	0.5	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0	0.2	GO:0021779	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.3	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.0	2.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	1.9	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0	1.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.5	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
0.0	1.0	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.0	2.5	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.5	GO:0038129	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0	0.0	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0	0.9	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.1	GO:0006288	base-excision repair, DNA ligation(GO:0006288)
0.0	0.1	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.0	0.3	GO:0021993	fourth ventricle development(GO:0021592) initiation of neural tube closure(GO:0021993)
0.0	0.3	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.8	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	8.1	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
0.0	0.9	GO:0030728	ovulation(GO:0030728)
0.0	0.4	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.3	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	1.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.3	GO:0043418	homocysteine catabolic process(GO:0043418)
0.0	1.5	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0	0.6	GO:0035886	vascular smooth muscle cell differentiation(GO:0035886)
0.0	8.9	GO:0031424	keratinization(GO:0031424)
0.0	0.4	GO:0006968	cellular defense response(GO:0006968)
0.0	0.7	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.2	GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0	2.1	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.0	0.1	GO:0034144	negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0	0.0	GO:0035378	carbon dioxide transmembrane transport(GO:0035378)
0.0	0.3	GO:0019722	calcium-mediated signaling(GO:0019722)
0.0	1.1	GO:0001556	oocyte maturation(GO:0001556)
0.0	0.1	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369)
0.0	0.7	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.0	1.2	GO:0006337	nucleosome disassembly(GO:0006337)
0.0	0.2	GO:0016078	tRNA catabolic process(GO:0016078)
0.0	0.9	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.1	GO:0060022	hard palate development(GO:0060022)
0.0	3.5	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
0.0	0.7	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0021650	vestibulocochlear nerve formation(GO:0021650)
0.0	0.3	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.3	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	1.3	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	1.9	GO:0002763	positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0	0.1	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0	0.4	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	1.8	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	0.3	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	1.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.5	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.2	GO:0071442	regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	1.9	GO:0050982	detection of mechanical stimulus(GO:0050982)
0.0	0.2	GO:0061034	olfactory bulb mitral cell layer development(GO:0061034)
0.0	0.3	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	1.7	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.3	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.0	0.6	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.3	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.0	1.0	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.0	0.2	GO:0048840	otolith development(GO:0048840)
0.0	0.2	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	1.5	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.2	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.0	0.4	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.9	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.3	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.2	GO:0030070	insulin processing(GO:0030070)
0.0	0.2	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0	0.2	GO:0019348	dolichol metabolic process(GO:0019348)
0.0	0.1	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.1	GO:0008380	RNA splicing(GO:0008380)
0.0	0.4	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:1901675	negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0	3.6	GO:0007498	mesoderm development(GO:0007498)
0.0	0.2	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	3.3	GO:0002250	adaptive immune response(GO:0002250)
0.0	0.3	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.3	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.4	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.5	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.3	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.0	0.1	GO:0003363	lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.2	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0035947	regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0	0.1	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.0	0.1	GO:0042441	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.5	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.6	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.2	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0070375	ERK5 cascade(GO:0070375) negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0	0.3	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.6	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.8	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.4	GO:0001765	membrane raft assembly(GO:0001765)
0.0	1.3	GO:0006506	GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0	0.4	GO:0040033	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0	0.4	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.2	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
0.0	0.5	GO:1903393	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.0	0.2	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.1	GO:0098507	polynucleotide 5' dephosphorylation(GO:0098507)
0.0	0.3	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.1	GO:1904468	negative regulation of tumor necrosis factor secretion(GO:1904468)
0.0	3.2	GO:0007062	sister chromatid cohesion(GO:0007062)
0.0	0.9	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.8	GO:0042100	B cell proliferation(GO:0042100)
0.0	0.1	GO:0030311	poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	0.2	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	1.4	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0	0.1	GO:0044026	DNA hypermethylation(GO:0044026)
0.0	0.1	GO:1904585	response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0	0.5	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.2	GO:0051013	microtubule severing(GO:0051013)
0.0	0.1	GO:1902109	negative regulation of mitochondrial membrane permeability(GO:0035795) negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.2	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.0	0.2	GO:0035494	SNARE complex disassembly(GO:0035494)
0.0	1.2	GO:0007030	Golgi organization(GO:0007030)
0.0	0.2	GO:0070933	histone H4 deacetylation(GO:0070933)
0.0	0.1	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.3	GO:0042407	cristae formation(GO:0042407)
0.0	0.5	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.4	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.1	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.6	GO:0021983	pituitary gland development(GO:0021983)
0.0	0.3	GO:0045023	G0 to G1 transition(GO:0045023)
0.0	0.2	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.4	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.3	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.0	0.3	GO:0030210	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0	0.2	GO:0046638	positive regulation of alpha-beta T cell differentiation(GO:0046638)
0.0	0.2	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.9	GO:0030239	myofibril assembly(GO:0030239)
0.0	0.5	GO:0043407	negative regulation of MAP kinase activity(GO:0043407)
0.0	0.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	1.0	GO:0018105	peptidyl-serine phosphorylation(GO:0018105)
0.0	0.2	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.3	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.2	GO:0035745	CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.0	9.6	GO:0051056	regulation of small GTPase mediated signal transduction(GO:0051056)
0.0	0.3	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.0	0.1	GO:1903288	positive regulation of potassium ion import(GO:1903288)
0.0	0.1	GO:0032196	transposition(GO:0032196)
0.0	0.7	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.2	GO:0015871	choline transport(GO:0015871) negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.2	GO:0061314	Notch signaling involved in heart development(GO:0061314)
0.0	0.5	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.0	0.1	GO:0046092	deoxycytidine metabolic process(GO:0046092)
0.0	0.1	GO:0018969	thiocyanate metabolic process(GO:0018969)
0.0	0.5	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.2	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.4	GO:0006396	RNA processing(GO:0006396)
0.0	0.5	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.2	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.2	GO:0035067	negative regulation of histone acetylation(GO:0035067)
0.0	0.1	GO:0023019	signal transduction involved in regulation of gene expression(GO:0023019)
0.0	0.8	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.4	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:0019542	acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0	0.4	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.3	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.2	GO:0032717	negative regulation of interleukin-8 production(GO:0032717)
0.0	0.7	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.5	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.8	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.0	2.3	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0	0.1	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0	0.2	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.1	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0	0.2	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.5	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.4	GO:0055008	cardiac muscle tissue morphogenesis(GO:0055008)
0.0	0.2	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.2	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.0	0.2	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.1	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.2	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	0.4	GO:0007595	lactation(GO:0007595)
0.0	0.7	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	7.9	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	1.7	GO:1903509	glycolipid metabolic process(GO:0006664) liposaccharide metabolic process(GO:1903509)
0.0	4.9	GO:0048193	Golgi vesicle transport(GO:0048193)
0.0	0.4	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.1	GO:0051958	methotrexate transport(GO:0051958)
0.0	0.7	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.4	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	0.4	GO:0046427	positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0	0.2	GO:0071539	protein localization to centrosome(GO:0071539)
0.0	0.3	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	0.1	GO:0032875	regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0	0.2	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.4	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.5	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
0.0	0.0	GO:0052651	monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0	0.3	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	0.1	GO:0014870	response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.7	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.8	GO:0030901	midbrain development(GO:0030901)
0.0	0.2	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.1	GO:2000773	negative regulation of cellular senescence(GO:2000773)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	5.4	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.6	4.2	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.5	2.6	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.4	3.0	GO:0036021	endolysosome lumen(GO:0036021)
0.4	1.3	GO:0032997	Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.4	4.1	GO:0032010	phagolysosome(GO:0032010)
0.3	7.7	GO:0042613	MHC class II protein complex(GO:0042613)
0.3	13.5	GO:0042101	T cell receptor complex(GO:0042101)
0.3	8.6	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.3	1.0	GO:0043614	multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.3	0.9	GO:0071745	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.3	5.3	GO:0030008	TRAPP complex(GO:0030008)
0.3	2.0	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3	17.6	GO:0001772	immunological synapse(GO:0001772)
0.3	3.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3	8.7	GO:0001891	phagocytic cup(GO:0001891)
0.3	0.8	GO:0002139	stereocilia coupling link(GO:0002139)
0.3	4.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.3	2.5	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2	0.2	GO:0005902	microvillus(GO:0005902)
0.2	1.6	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.2	4.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.2	3.3	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.2	3.0	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2	0.8	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.2	1.0	GO:0016035	zeta DNA polymerase complex(GO:0016035)
0.2	6.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.2	1.5	GO:0016012	sarcoglycan complex(GO:0016012)
0.2	0.5	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	0.6	GO:0035841	new growing cell tip(GO:0035841)
0.1	0.9	GO:1990037	Lewy body core(GO:1990037)
0.1	0.8	GO:0031302	intrinsic component of endosome membrane(GO:0031302)
0.1	1.1	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.1	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.1	6.9	GO:0035371	microtubule plus-end(GO:0035371)
0.1	1.4	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.1	0.3	GO:0042720	mitochondrial inner membrane peptidase complex(GO:0042720)
0.1	0.6	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1	0.9	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.1	1.7	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.4	GO:0031523	Myb complex(GO:0031523)
0.1	1.5	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	2.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	2.0	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	0.8	GO:0070695	FHF complex(GO:0070695)
0.1	1.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	0.3	GO:1902912	pyruvate kinase complex(GO:1902912)
0.1	0.9	GO:0036128	CatSper complex(GO:0036128)
0.1	12.0	GO:0070821	tertiary granule membrane(GO:0070821)
0.1	0.6	GO:0033565	ESCRT-0 complex(GO:0033565)
0.1	0.5	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.1	2.9	GO:0030018	Z disc(GO:0030018)
0.1	3.8	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	1.2	GO:0035102	PRC1 complex(GO:0035102)
0.1	0.6	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	0.2	GO:0002944	cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.1	3.0	GO:0005859	muscle myosin complex(GO:0005859)
0.1	0.7	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	1.0	GO:0030427	site of polarized growth(GO:0030427)
0.1	1.0	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	0.6	GO:0005827	polar microtubule(GO:0005827)
0.1	0.9	GO:0030027	lamellipodium(GO:0030027)
0.1	21.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	2.8	GO:0005720	nuclear heterochromatin(GO:0005720)
0.1	0.2	GO:1990723	cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1	0.2	GO:0005715	late recombination nodule(GO:0005715)
0.1	5.5	GO:0045095	keratin filament(GO:0045095)
0.1	0.2	GO:1990667	PCSK9-AnxA2 complex(GO:1990667)
0.1	0.3	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1	0.2	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.1	3.6	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	1.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1	0.9	GO:0000815	ESCRT III complex(GO:0000815)
0.1	3.0	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.1	0.7	GO:0042584	chromaffin granule membrane(GO:0042584)
0.1	1.8	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1	2.4	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	3.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.3	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.6	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	1.8	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.1	GO:0097422	tubular endosome(GO:0097422)
0.0	0.2	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.7	GO:0060091	kinocilium(GO:0060091)
0.0	1.8	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0002947	tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0	0.3	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	1.2	GO:0032590	dendrite membrane(GO:0032590)
0.0	1.0	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	1.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.0	0.2	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	6.7	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	1.4	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.5	GO:0016600	flotillin complex(GO:0016600)
0.0	1.4	GO:0038201	TOR complex(GO:0038201)
0.0	0.9	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	3.2	GO:0035579	specific granule membrane(GO:0035579)
0.0	0.5	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.4	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	1.0	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.5	GO:0030870	Mre11 complex(GO:0030870)
0.0	5.8	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.2	GO:1990246	uniplex complex(GO:1990246)
0.0	0.5	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	1.0	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.5	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.3	GO:0061617	MICOS complex(GO:0061617)
0.0	0.1	GO:0000811	GINS complex(GO:0000811)
0.0	3.8	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.2	GO:0055037	recycling endosome(GO:0055037)
0.0	0.2	GO:0036449	microtubule minus-end(GO:0036449)
0.0	0.8	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.6	GO:0043596	nuclear replication fork(GO:0043596)
0.0	5.1	GO:0016605	PML body(GO:0016605)
0.0	0.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.3	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	5.9	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.4	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	1.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	1.7	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.6	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.1	GO:0071006	U2-type catalytic step 1 spliceosome(GO:0071006)
0.0	0.1	GO:0034657	GID complex(GO:0034657)
0.0	0.4	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.3	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0	0.4	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.4	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	2.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.7	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0	1.2	GO:0090544	BAF-type complex(GO:0090544)
0.0	1.3	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.0	0.3	GO:0098576	lumenal side of membrane(GO:0098576)
0.0	2.7	GO:0005882	intermediate filament(GO:0005882)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	1.0	GO:0031904	endosome lumen(GO:0031904)
0.0	0.2	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.3	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.3	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	11.0	GO:0005769	early endosome(GO:0005769)
0.0	0.3	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	1.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.9	GO:0070469	respiratory chain(GO:0070469)
0.0	2.0	GO:0070820	tertiary granule(GO:0070820)
0.0	1.0	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.2	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.3	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0005726	perichromatin fibrils(GO:0005726)
0.0	4.3	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.1	GO:0097196	Shu complex(GO:0097196)
0.0	0.1	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.5	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0005873	plus-end kinesin complex(GO:0005873)
0.0	0.2	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	2.4	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.7	GO:0035580	specific granule lumen(GO:0035580)
0.0	0.5	GO:0000145	exocyst(GO:0000145)
0.0	0.8	GO:0005605	basal lamina(GO:0005605)
0.0	0.2	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.4	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	3.1	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	0.2	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.4	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.6	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.1	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.0	0.3	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.6	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.4	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.2	GO:0016013	syntrophin complex(GO:0016013)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.4	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.0	0.9	GO:0034774	secretory granule lumen(GO:0034774)
0.0	0.8	GO:0016459	myosin complex(GO:0016459)
0.0	0.9	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	1.0	GO:0072562	blood microparticle(GO:0072562)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	1.6	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	7.4	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	0.9	GO:0034399	nuclear periphery(GO:0034399)
0.0	0.6	GO:0036064	ciliary basal body(GO:0036064)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.6	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	0.7	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	9.9	GO:0005174	CD40 receptor binding(GO:0005174)
2.0	10.0	GO:0015254	glycerol channel activity(GO:0015254)
1.4	4.3	GO:0004108	citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
1.2	1.2	GO:0005499	vitamin D binding(GO:0005499)
0.9	2.8	GO:0016495	C-X3-C chemokine receptor activity(GO:0016495)
0.9	2.6	GO:0070119	ciliary neurotrophic factor binding(GO:0070119)
0.7	2.2	GO:0050146	nucleoside phosphotransferase activity(GO:0050146)
0.6	3.1	GO:0019770	IgG receptor activity(GO:0019770)
0.6	1.8	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.6	1.8	GO:0019781	NEDD8 activating enzyme activity(GO:0019781)
0.6	6.6	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.6	2.3	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.5	1.5	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.4	2.2	GO:0008665	2'-phosphotransferase activity(GO:0008665)
0.4	2.1	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.4	1.6	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.4	12.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4	1.8	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3	2.1	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.3	1.0	GO:0005148	prolactin receptor binding(GO:0005148)
0.3	4.3	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3	1.9	GO:0023024	MHC class I protein complex binding(GO:0023024)
0.3	2.4	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.3	0.9	GO:0016826	N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.3	1.7	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3	9.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.3	0.8	GO:0030572	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.3	10.2	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.3	2.4	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2	2.2	GO:0038051	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2	1.7	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2	5.8	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.2	7.9	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.2	1.2	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.2	0.7	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
0.2	0.9	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.2	1.9	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2	1.6	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.2	1.2	GO:0051373	FATZ binding(GO:0051373)
0.2	1.4	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.2	1.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.2	0.6	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.2	4.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.2	4.6	GO:0050700	CARD domain binding(GO:0050700)
0.2	0.5	GO:0097689	iron channel activity(GO:0097689)
0.2	5.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.2	0.7	GO:0071885	N-terminal protein N-methyltransferase activity(GO:0071885)
0.2	3.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2	0.7	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.2	2.5	GO:0030280	structural constituent of epidermis(GO:0030280)
0.2	10.9	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.2	3.7	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.2	1.0	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	6.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	1.6	GO:0031013	troponin I binding(GO:0031013)
0.1	1.4	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1	1.1	GO:0005124	N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.1	0.4	GO:0001156	TFIIIC-class transcription factor binding(GO:0001156)
0.1	10.0	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1	0.8	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.9	GO:0008955	peptidoglycan glycosyltransferase activity(GO:0008955)
0.1	1.3	GO:0019863	IgE binding(GO:0019863)
0.1	0.6	GO:0031208	POZ domain binding(GO:0031208)
0.1	4.3	GO:0031489	myosin V binding(GO:0031489)
0.1	1.2	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.1	0.9	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.1	0.8	GO:0016530	metallochaperone activity(GO:0016530)
0.1	20.3	GO:0003823	antigen binding(GO:0003823)
0.1	1.7	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.1	0.2	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1	4.0	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1	1.9	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1	0.4	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	1.3	GO:0032393	MHC class I receptor activity(GO:0032393)
0.1	1.3	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.9	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1	1.5	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1	3.5	GO:0002162	dystroglycan binding(GO:0002162)
0.1	2.7	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	1.2	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1	4.1	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	1.7	GO:0019957	C-C chemokine binding(GO:0019957)
0.1	4.5	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	0.5	GO:0047256	beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1	0.3	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1	0.4	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.1	1.9	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	0.6	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.1	0.5	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	2.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	2.4	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	2.3	GO:0038187	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1	0.5	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1	5.4	GO:0015026	coreceptor activity(GO:0015026)
0.1	6.9	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	0.6	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.3	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.6	GO:0001515	opioid peptide activity(GO:0001515)
0.1	6.3	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.1	1.8	GO:0071837	HMG box domain binding(GO:0071837)
0.1	1.5	GO:0000150	recombinase activity(GO:0000150)
0.1	0.5	GO:0070728	leucine binding(GO:0070728)
0.1	0.2	GO:1990698	palmitoleoyltransferase activity(GO:1990698)
0.1	0.1	GO:0034185	apolipoprotein binding(GO:0034185)
0.1	2.9	GO:0043236	laminin binding(GO:0043236)
0.1	0.3	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.1	0.4	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1	0.3	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1	0.4	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1	0.3	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1	1.0	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	4.4	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1	0.8	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.5	GO:1990254	keratin filament binding(GO:1990254)
0.1	0.2	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
0.1	1.8	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.3	GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1	0.3	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.1	0.3	GO:0047787	delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.1	0.2	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1	2.6	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.5	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.1	1.3	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.2	GO:0003943	N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1	3.9	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1	0.2	GO:0030626	U12 snRNA binding(GO:0030626)
0.1	0.4	GO:0042609	CD4 receptor binding(GO:0042609)
0.1	0.3	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.1	0.2	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1	1.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	1.0	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.4	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	0.2	GO:0001147	transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1	0.2	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	0.2	GO:0034602	oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1	0.8	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.1	0.4	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0	0.9	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.4	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	1.0	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	1.4	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.3	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.2	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.0	0.5	GO:0015181	arginine transmembrane transporter activity(GO:0015181)
0.0	0.6	GO:0001851	complement component C3b binding(GO:0001851)
0.0	0.2	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	2.0	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.2	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.3	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.6	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.5	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	2.0	GO:0070888	E-box binding(GO:0070888)
0.0	1.1	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.8	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.3	GO:0005119	smoothened binding(GO:0005119)
0.0	0.2	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.0	0.7	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	1.0	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.6	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.4	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.0	0.9	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	1.4	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.2	GO:0039552	RIG-I binding(GO:0039552)
0.0	0.5	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.5	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.0	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
0.0	0.9	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.3	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	1.2	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	1.4	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	1.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.5	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.4	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.2	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.2	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0	0.2	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.6	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.5	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	2.9	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.2	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.1	GO:0061711	N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0	0.7	GO:0005522	profilin binding(GO:0005522)
0.0	0.6	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	1.7	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0008200	ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.0	0.5	GO:0015266	protein channel activity(GO:0015266)
0.0	0.3	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	1.0	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	1.2	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.8	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0	0.7	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	1.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.4	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.6	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.3	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	1.1	GO:0005123	death receptor binding(GO:0005123)
0.0	0.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	1.3	GO:0034061	DNA polymerase activity(GO:0034061)
0.0	0.5	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	3.1	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.4	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.9	GO:0030228	lipoprotein particle receptor activity(GO:0030228)
0.0	0.3	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.6	GO:0030547	receptor inhibitor activity(GO:0030547)
0.0	0.5	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.2	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.1	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.0	0.5	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.5	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.0	0.7	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	0.2	GO:0035473	lipase binding(GO:0035473)
0.0	0.1	GO:0050333	thiamin-triphosphatase activity(GO:0050333)
0.0	0.2	GO:0035500	MH2 domain binding(GO:0035500)
0.0	2.1	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.3	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.2	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.5	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0052642	lysophosphatidic acid phosphatase activity(GO:0052642)
0.0	0.9	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0004951	cholecystokinin receptor activity(GO:0004951)
0.0	0.1	GO:0004651	polynucleotide 5'-phosphatase activity(GO:0004651)
0.0	1.6	GO:0043022	ribosome binding(GO:0043022)
0.0	0.3	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.2	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.3	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0	0.9	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.4	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.0	0.2	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	1.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.9	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.9	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	1.0	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0	0.4	GO:0070628	proteasome binding(GO:0070628)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.2	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.3	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.2	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.0	0.6	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	5.9	GO:0000287	magnesium ion binding(GO:0000287)
0.0	0.1	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.5	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0005137	interleukin-5 receptor binding(GO:0005137)
0.0	1.8	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.1	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	1.7	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	0.7	GO:0005521	lamin binding(GO:0005521)
0.0	0.9	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.5	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.6	GO:0071949	FAD binding(GO:0071949)
0.0	0.5	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0036393	thiocyanate peroxidase activity(GO:0036393)
0.0	1.1	GO:0003678	DNA helicase activity(GO:0003678)
0.0	0.3	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	2.9	GO:0004386	helicase activity(GO:0004386)
0.0	0.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	1.0	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0	1.6	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.2	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.9	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.6	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.4	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.8	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.8	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.1	GO:0004797	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0	2.7	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.9	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	1.2	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	9.2	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.3	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	5.5	GO:0030246	carbohydrate binding(GO:0030246)
0.0	1.5	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.2	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.4	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.3	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.2	GO:0070513	death domain binding(GO:0070513)
0.0	1.0	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.5	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.8	GO:0019003	GDP binding(GO:0019003)
0.0	1.0	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.1	GO:0015350	methotrexate transporter activity(GO:0015350)
0.0	0.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.1	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.0	0.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	6.1	GO:0030695	GTPase regulator activity(GO:0030695)
0.0	0.1	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0	3.4	GO:0051020	GTPase binding(GO:0051020)
0.0	0.2	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.4	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	0.1	GO:0052654	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0	0.5	GO:0030507	spectrin binding(GO:0030507)
0.0	0.9	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.2	GO:0042166	acetylcholine binding(GO:0042166)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	20.3	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2	8.7	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	2.6	ST STAT3 PATHWAY	STAT3 Pathway
0.1	0.7	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	4.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	10.4	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	6.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.1	5.4	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	7.8	PID ARF6 PATHWAY	Arf6 signaling events
0.1	1.9	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	2.9	PID EPO PATHWAY	EPO signaling pathway
0.1	3.0	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	1.2	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	4.0	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	7.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	1.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	2.6	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	0.5	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.1	6.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	2.0	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	4.0	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	1.7	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.1	1.6	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.7	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.9	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	1.4	PID ARF 3PATHWAY	Arf1 pathway
0.0	4.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	1.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.9	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	5.7	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	1.6	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	2.4	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	1.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	2.7	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.8	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.7	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	1.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.7	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	1.4	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	2.9	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.6	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	2.6	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.6	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.5	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.7	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	1.0	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.5	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	1.1	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	1.4	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.8	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	2.6	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	3.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.8	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.2	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	1.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.5	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.2	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.6	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	1.3	PID E2F PATHWAY	E2F transcription factor network
0.0	0.5	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.5	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.3	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.3	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.3	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	9.9	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.3	3.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.3	8.8	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3	6.4	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.2	12.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.2	4.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.2	0.6	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	3.0	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	1.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	4.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	15.9	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	4.6	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.1	2.8	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	6.9	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	2.7	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	2.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	4.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.7	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	1.2	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	2.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	4.6	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	25.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	2.0	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	2.0	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	5.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	4.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	6.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	1.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	2.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	2.0	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	2.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	0.8	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	8.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	0.9	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.1	1.7	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	0.3	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	6.0	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.1	0.6	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	1.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.1	0.8	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	3.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	6.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	1.0	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	1.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	10.3	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	1.9	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.0	1.3	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.8	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	2.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	1.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	1.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.0	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.2	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	1.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.6	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	1.7	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	1.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.5	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.9	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	1.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.6	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	6.1	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	1.0	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.5	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	1.7	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	1.3	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.5	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	1.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	1.0	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.1	REACTOME UNFOLDED PROTEIN RESPONSE	Genes involved in Unfolded Protein Response
0.0	0.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.4	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.9	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.5	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.2	REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0	0.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.4	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.3	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.4	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)

Results for MIXL1_GSX1_BSX_MEOX2_LHX4

Z-value: 1.14

Motif logo

Transcription factors associated with MIXL1_GSX1_BSX_MEOX2_LHX4

Activity-expression correlation:

Activity profile of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Sorted Z-values of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: