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Illumina Body Map 2, young vs old

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Results for MYB

Z-value: 0.57

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Transcription factors associated with MYB

Gene Symbol Gene ID Gene Info
ENSG00000118513.14 MYB proto-oncogene, transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MYBhg19_v2_chr6_+_135502501_1355026520.318.4e-02Click!

Activity profile of MYB motif

Sorted Z-values of MYB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_54814288 13.10 ENST00000585477.1
biorientation of chromosomes in cell division 1-like 2
chr15_+_97326619 12.77 ENST00000328504.3
spermatogenesis associated 8
chr9_-_104357277 12.16 ENST00000374806.1
protein phosphatase 3, regulatory subunit B, beta
chr3_+_52444651 12.01 ENST00000327906.3
PHD finger protein 7
chr8_-_39695719 11.71 ENST00000347580.4
ENST00000379853.2
ENST00000521880.1
ADAM metallopeptidase domain 2
chr6_+_22569784 11.48 ENST00000510882.2
hepatoma derived growth factor-like 1
chr22_-_20461786 10.86 ENST00000426804.1
RIMS binding protein 3
chr1_+_156308245 10.85 ENST00000368253.2
ENST00000470342.1
ENST00000368254.1
TSSK6 activating co-chaperone
chr16_+_66613351 10.22 ENST00000379486.2
ENST00000268595.2
CKLF-like MARVEL transmembrane domain containing 2
chr7_+_72742178 10.20 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FK506 binding protein 6, 36kDa
chr5_+_10441970 10.16 ENST00000274134.4
rhophilin associated tail protein 1-like
chr4_+_155702496 10.13 ENST00000510397.1
RNA binding motif protein 46
chr10_+_32735030 10.06 ENST00000277657.6
ENST00000362006.5
coiled-coil domain containing 7
chr15_+_97326659 9.97 ENST00000558553.1
spermatogenesis associated 8
chr14_+_29236269 9.97 ENST00000313071.4
forkhead box G1
chr6_+_22569678 9.89 ENST00000230012.3
hepatoma derived growth factor-like 1
chr5_+_169659950 9.82 ENST00000593851.1
chromosome 5 open reading frame 58
chr4_+_123300664 9.73 ENST00000388725.2
adenosine deaminase domain containing 1 (testis-specific)
chr4_+_44019074 9.67 ENST00000512678.1
RP11-328N19.1
chr11_+_18433840 9.41 ENST00000541669.1
ENST00000280704.4
lactate dehydrogenase C
chr22_+_21737663 9.38 ENST00000434111.1
RIMS binding protein 3B
chr1_+_92414928 9.36 ENST00000362005.3
ENST00000370389.2
ENST00000399546.2
ENST00000423434.1
ENST00000394530.3
ENST00000440509.1
bromodomain, testis-specific
chr8_-_39695764 9.06 ENST00000265708.4
ADAM metallopeptidase domain 2
chr4_+_123300591 9.04 ENST00000439307.1
ENST00000388724.2
adenosine deaminase domain containing 1 (testis-specific)
chr4_+_123300121 8.81 ENST00000446706.1
ENST00000296513.2
adenosine deaminase domain containing 1 (testis-specific)
chr7_+_72742162 8.36 ENST00000431982.2
FK506 binding protein 6, 36kDa
chr3_-_50383096 8.35 ENST00000442887.1
ENST00000360165.3
zinc finger, MYND-type containing 10
chr11_+_130184888 8.23 ENST00000602376.1
ENST00000532116.3
ENST00000602310.1
RP11-121M22.1
chr2_+_132160448 8.09 ENST00000437751.1
long intergenic non-protein coding RNA 1120
chr1_+_156308403 7.85 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSSK6 activating co-chaperone
chr12_-_54867352 7.67 ENST00000305879.5
gametocyte specific factor 1
chr17_-_56565736 7.63 ENST00000323777.3
heat shock transcription factor family member 5
chr16_-_48189898 7.44 ENST00000527640.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
chr1_+_53925063 7.43 ENST00000371445.3
DMRT-like family B with proline-rich C-terminal, 1
chr11_-_123756334 7.31 ENST00000528595.1
ENST00000375026.2
transmembrane protein 225
chr5_-_41071392 7.09 ENST00000399564.4
maestro heat-like repeat family member 2B
chr5_-_157079428 7.04 ENST00000265007.6
SRY (sex determining region Y)-box 30
chr17_-_33288419 7.03 ENST00000421975.3
chaperonin containing TCP1, subunit 6B (zeta 2)
chr17_+_58499844 6.96 ENST00000269127.4
chromosome 17 open reading frame 64
chr5_-_157079372 6.95 ENST00000311371.5
SRY (sex determining region Y)-box 30
chr4_+_128651530 6.89 ENST00000281154.4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr17_-_33288522 6.86 ENST00000314144.5
chaperonin containing TCP1, subunit 6B (zeta 2)
chr17_-_7197881 6.85 ENST00000007699.5
Y box binding protein 2
chr3_-_172859017 6.81 ENST00000351008.3
spermatogenesis associated 16
chr13_+_25338290 6.81 ENST00000255324.5
ENST00000381921.1
ENST00000255325.6
ring finger protein 17
chr17_-_33288467 6.67 ENST00000436961.3
chaperonin containing TCP1, subunit 6B (zeta 2)
chr19_+_35396219 6.58 ENST00000595783.1
CTC-523E23.6
chr12_+_107078474 6.56 ENST00000552866.1
ENST00000229387.5
regulatory factor X, 4 (influences HLA class II expression)
chr7_-_88425025 6.42 ENST00000297203.2
chromosome 7 open reading frame 62
chr11_-_111383064 6.37 ENST00000525791.1
ENST00000456861.2
ENST00000356018.2
B-cell translocation gene 4
chr8_+_39442097 6.32 ENST00000265707.5
ENST00000379866.1
ENST00000520772.1
ENST00000541111.1
ADAM metallopeptidase domain 18
chr17_-_3375033 6.27 ENST00000268981.5
ENST00000397168.3
ENST00000572969.1
ENST00000355380.4
ENST00000571553.1
ENST00000574797.1
ENST00000575375.1
spermatogenesis associated 22
chr5_-_101834712 6.16 ENST00000506729.1
ENST00000389019.3
ENST00000379810.1
solute carrier organic anion transporter family, member 6A1
chr9_+_6328360 6.06 ENST00000381428.1
ENST00000314556.3
tumor protein D52-like 3
chr17_+_58499066 6.05 ENST00000474834.1
chromosome 17 open reading frame 64
chr19_+_51754332 5.98 ENST00000601727.1
SIGLEC family like 1
chr14_+_21785693 5.93 ENST00000382933.4
ENST00000557351.1
retinitis pigmentosa GTPase regulator interacting protein 1
chr1_-_182922505 5.88 ENST00000367547.3
SHC SH2-domain binding protein 1-like
chr11_-_68519026 5.79 ENST00000255087.5
metallothionein-like 5, testis-specific (tesmin)
chr2_-_111435610 5.79 ENST00000447014.1
ENST00000420328.1
ENST00000535254.1
ENST00000409311.1
ENST00000302759.6
BUB1 mitotic checkpoint serine/threonine kinase
chr19_+_51754526 5.78 ENST00000596117.1
SIGLEC family like 1
chr3_-_71834318 5.77 ENST00000353065.3
prokineticin 2
chr9_+_131219250 5.69 ENST00000470061.1
outer dense fiber of sperm tails 2
chr14_+_54863739 5.62 ENST00000541304.1
cyclin-dependent kinase inhibitor 3
chr5_-_101834617 5.60 ENST00000513675.1
ENST00000379807.3
solute carrier organic anion transporter family, member 6A1
chr4_+_155702365 5.57 ENST00000514866.1
ENST00000281722.3
RNA binding motif protein 46
chr14_+_54863682 5.43 ENST00000543789.2
ENST00000442975.2
ENST00000458126.2
ENST00000556102.2
cyclin-dependent kinase inhibitor 3
chr7_+_100183927 5.41 ENST00000241071.6
ENST00000360609.2
F-box protein 24
chr17_-_3417062 5.39 ENST00000570318.1
ENST00000541913.1
spermatogenesis associated 22
chr14_+_54863667 5.31 ENST00000335183.6
cyclin-dependent kinase inhibitor 3
chr22_-_21905120 5.17 ENST00000331505.5
RIMS binding protein 3C
chr22_+_30476163 5.14 ENST00000336726.6
HORMA domain containing 2
chr9_+_131219179 5.13 ENST00000372791.3
outer dense fiber of sperm tails 2
chr3_+_181670131 5.10 ENST00000482787.3
ENST00000600750.1
ENST00000596820.1
ENST00000490001.1
ENST00000467313.1
ENST00000474045.1
RP11-416O18.1
chr13_-_52026730 5.04 ENST00000420668.2
integrator complex subunit 6
chr15_+_69222827 5.03 ENST00000310673.3
ENST00000448182.3
ENST00000260364.5
sperm equatorial segment protein 1
NADPH oxidase, EF-hand calcium binding domain 5
chr19_-_35395961 5.02 ENST00000605047.1
CTC-523E23.15
chr11_+_125774258 4.96 ENST00000263576.6
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr10_-_46167722 4.90 ENST00000374366.3
ENST00000344646.5
zinc finger, AN1-type domain 4
chr5_-_156593273 4.89 ENST00000302938.4
family with sequence similarity 71, member B
chr9_-_127269661 4.85 ENST00000373588.4
nuclear receptor subfamily 5, group A, member 1
chr1_-_211848899 4.84 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NIMA-related kinase 2
chrX_+_102965835 4.80 ENST00000319560.6
transmembrane protein 31
chr3_-_150421728 4.74 ENST00000295910.6
ENST00000491361.1
family with sequence similarity 194, member A
chr11_+_45743858 4.69 ENST00000532307.1
CTD-2210P24.1
chr17_-_39093672 4.65 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
keratin 23 (histone deacetylase inducible)
chr15_+_74165945 4.58 ENST00000535547.2
ENST00000300504.2
ENST00000562056.1
TBC1 domain family, member 21
chr1_+_179561011 4.56 ENST00000294848.8
ENST00000444136.1
tudor domain containing 5
chr12_+_29542557 4.55 ENST00000550906.1
OVCH1 antisense RNA 1
chr15_+_73735490 4.52 ENST00000331090.6
ENST00000560581.1
chromosome 15 open reading frame 60
chr19_+_36195429 4.51 ENST00000392197.2
zinc finger and BTB domain containing 32
chr9_+_6328338 4.47 ENST00000344545.5
tumor protein D52-like 3
chr13_-_103426112 4.46 ENST00000376032.4
ENST00000376029.3
testis expressed 30
chr3_-_59035673 4.44 ENST00000491845.1
ENST00000472469.1
ENST00000471288.1
ENST00000295966.7
chromosome 3 open reading frame 67
chr8_-_101157680 4.42 ENST00000428847.2
F-box protein 43
chr13_-_103426081 4.41 ENST00000376022.1
ENST00000376021.4
testis expressed 30
chr1_-_109656439 4.41 ENST00000369949.4
chromosome 1 open reading frame 194
chr1_+_212208919 4.40 ENST00000366991.4
ENST00000542077.1
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr16_-_11363178 4.39 ENST00000312693.3
transition protein 2 (during histone to protamine replacement)
chr19_+_33210645 4.37 ENST00000444215.2
tudor domain containing 12
chr10_-_64028466 4.36 ENST00000395265.1
ENST00000373789.3
ENST00000395260.3
rhotekin 2
chr17_-_8702667 4.32 ENST00000329805.4
major facilitator superfamily domain containing 6-like
chr6_+_46655612 4.31 ENST00000544460.1
tudor domain containing 6
chr11_+_45743931 4.30 ENST00000530051.1
CTD-2210P24.1
chr15_+_72690614 4.30 ENST00000341689.3
ENST00000567679.1
transmembrane protein 202
chr4_-_57687847 4.30 ENST00000504762.1
ENST00000248701.4
ENST00000506738.1
serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
chr1_+_166958504 4.27 ENST00000447624.1
maelstrom spermatogenic transposon silencer
chrY_+_22737678 4.27 ENST00000382772.3
eukaryotic translation initiation factor 1A, Y-linked
chr14_+_104394770 4.27 ENST00000409874.4
ENST00000339063.5
tudor domain containing 9
chr17_-_46894576 4.24 ENST00000393382.3
tubulin tyrosine ligase-like family, member 6
chr1_-_32827682 4.23 ENST00000432622.1
family with sequence similarity 229, member A
chr15_+_59499031 4.22 ENST00000307144.4
lactate dehydrogenase A-like 6B
chr11_-_116708302 4.13 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
apolipoprotein A-I
chr12_-_6961050 4.12 ENST00000538862.2
cell division cycle associated 3
chr17_-_76573465 4.08 ENST00000585328.1
ENST00000389840.5
dynein, axonemal, heavy chain 17
chr6_+_167412835 4.05 ENST00000349556.4
FGFR1 oncogene partner
chr1_+_166958497 4.03 ENST00000367870.2
maelstrom spermatogenic transposon silencer
chr15_+_75491203 3.96 ENST00000562637.1
chromosome 15 open reading frame 39
chr19_+_46236509 3.94 ENST00000457052.2
Uncharacterized protein
chr17_-_60885645 3.92 ENST00000544856.2
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr17_-_60885659 3.88 ENST00000311269.5
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr19_-_16738984 3.87 ENST00000600060.1
ENST00000263390.3
mediator complex subunit 26
chr3_-_52188397 3.87 ENST00000474012.1
ENST00000296484.2
POC1 centriolar protein A
chr17_-_60885700 3.86 ENST00000583600.1
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chrX_-_70128580 3.81 ENST00000374333.2
testis expressed 11
chr1_-_85155939 3.78 ENST00000603677.1
synovial sarcoma, X breakpoint 2 interacting protein
chr20_-_58508702 3.76 ENST00000357552.3
ENST00000425931.1
synaptonemal complex protein 2
chr7_-_72992663 3.72 ENST00000432538.1
transducin (beta)-like 2
chr6_-_27279949 3.71 ENST00000444565.1
ENST00000377451.2
POM121 transmembrane nucleoporin-like 2
chr13_+_25670268 3.71 ENST00000281589.3
poly(A) binding protein, cytoplasmic 3
chr22_+_51176624 3.70 ENST00000216139.5
ENST00000529621.1
acrosin
chr17_+_18647326 3.67 ENST00000395667.1
ENST00000395665.4
ENST00000308799.4
ENST00000301938.4
F-box and WD repeat domain containing 10
chrX_-_125686784 3.63 ENST00000371126.1
DDB1 and CUL4 associated factor 12-like 1
chr1_+_43824669 3.62 ENST00000372462.1
cell division cycle 20
chr1_-_112106578 3.61 ENST00000369717.4
adenosine A3 receptor
chr1_+_43824577 3.60 ENST00000310955.6
cell division cycle 20
chr1_-_109203997 3.56 ENST00000370032.5
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr3_-_71834207 3.55 ENST00000295619.3
prokineticin 2
chr22_-_22090043 3.54 ENST00000403503.1
yippee-like 1 (Drosophila)
chr1_+_26517052 3.54 ENST00000338855.2
ENST00000456354.2
cation channel, sperm associated 4
chr1_+_41707996 3.49 ENST00000425554.1
RP11-399E6.1
chr15_+_40886439 3.48 ENST00000532056.1
ENST00000399668.2
cancer susceptibility candidate 5
chr7_-_123174610 3.47 ENST00000324698.6
ENST00000434450.1
IQ motif and ubiquitin domain containing
chr1_+_244624678 3.47 ENST00000366534.4
ENST00000366533.4
ENST00000428042.1
ENST00000366531.3
chromosome 1 open reading frame 101
chr15_-_71407806 3.47 ENST00000566432.1
ENST00000567117.1
cancer/testis antigen 62
chr11_+_85566422 3.42 ENST00000342404.3
coiled-coil domain containing 83
chr1_-_112106556 3.41 ENST00000443498.1
adenosine A3 receptor
chr15_-_71407833 3.40 ENST00000449977.2
cancer/testis antigen 62
chr14_+_94640633 3.39 ENST00000304338.3
protein phosphatase 4, regulatory subunit 4
chr11_+_125774362 3.38 ENST00000530414.1
ENST00000530129.2
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr1_+_92414952 3.38 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
bromodomain, testis-specific
chr4_-_186392843 3.37 ENST00000393540.3
ENST00000506876.1
coiled-coil domain containing 110
chr15_+_84116106 3.34 ENST00000535412.1
ENST00000324537.5
SH3-domain GRB2-like 3
chr15_+_93124059 3.33 ENST00000555864.1
RP11-386M24.3
chr14_+_94385235 3.33 ENST00000557719.1
ENST00000267594.5
family with sequence similarity 181, member A
chr20_-_34117447 3.27 ENST00000246199.2
ENST00000424444.1
ENST00000374345.4
ENST00000444723.1
chromosome 20 open reading frame 173
chr11_+_6255995 3.27 ENST00000533426.1
cyclic nucleotide gated channel alpha 4
chr7_-_72992865 3.27 ENST00000452475.1
transducin (beta)-like 2
chrX_-_70128554 3.27 ENST00000395889.2
testis expressed 11
chr22_-_46659219 3.26 ENST00000253255.5
polycystin (PKD) family receptor for egg jelly
chr19_-_9609272 3.26 ENST00000301480.4
zinc finger protein 560
chr1_-_235098935 3.23 ENST00000423175.1
RP11-443B7.1
chr7_+_48075108 3.22 ENST00000420324.1
ENST00000435376.1
ENST00000430738.1
ENST00000348904.3
ENST00000539619.1
chromosome 7 open reading frame 57
chrX_-_102531717 3.22 ENST00000372680.1
transcription elongation factor A (SII)-like 5
chrX_-_151922340 3.21 ENST00000370284.1
ENST00000543232.1
ENST00000393876.1
ENST00000393872.3
melanoma antigen family A, 2
chr2_+_26624775 3.21 ENST00000288710.2
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr3_+_113666748 3.19 ENST00000330212.3
ENST00000498275.1
zinc finger, DHHC-type containing 23
chr17_+_8243154 3.18 ENST00000328248.2
ENST00000584943.1
outer dense fiber of sperm tails 4
chr13_-_60737898 3.16 ENST00000377908.2
ENST00000400319.1
ENST00000400320.1
ENST00000267215.4
diaphanous-related formin 3
chr9_-_23821273 3.16 ENST00000380110.4
ELAV like neuron-specific RNA binding protein 2
chr17_-_58499698 3.14 ENST00000590297.1
ubiquitin specific peptidase 32
chr7_-_72993033 3.14 ENST00000305632.5
transducin (beta)-like 2
chr17_-_46262541 3.12 ENST00000579336.1
src kinase associated phosphoprotein 1
chr15_+_45722727 3.11 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
chromosome 15 open reading frame 48
chr7_+_102105370 3.10 ENST00000292616.5
leucine-rich repeats and WD repeat domain containing 1
chr11_+_93063878 3.09 ENST00000298050.3
coiled-coil domain containing 67
chr6_+_44126545 3.09 ENST00000532171.1
ENST00000398776.1
ENST00000542245.1
calpain 11
chr1_-_68962782 3.06 ENST00000456315.2
DEP domain containing 1
chr16_+_66600294 3.06 ENST00000535705.1
ENST00000332695.7
ENST00000336328.6
ENST00000528324.1
ENST00000531885.1
ENST00000529506.1
ENST00000457188.2
ENST00000533666.1
ENST00000533953.1
ENST00000379500.2
ENST00000328020.6
CKLF-like MARVEL transmembrane domain containing 1
chr3_-_128712906 3.05 ENST00000511438.1
KIAA1257
chrX_+_151883090 3.04 ENST00000370293.2
ENST00000423993.1
ENST00000447530.1
ENST00000458057.1
ENST00000331220.2
ENST00000422085.1
ENST00000453150.1
ENST00000409560.1
melanoma antigen family A, 2B
chr19_+_38826415 3.04 ENST00000410018.1
ENST00000409235.3
catsper channel auxiliary subunit gamma
chr19_+_827823 3.04 ENST00000233997.2
azurocidin 1
chr7_+_53103320 3.04 ENST00000408890.4
POM121 transmembrane nucleoporin-like 12
chr18_-_6929797 3.03 ENST00000581725.1
ENST00000583316.1
long intergenic non-protein coding RNA 668
chr4_-_141348789 2.99 ENST00000414773.1
calmegin
chrX_+_136648297 2.99 ENST00000287538.5
Zic family member 3
chr5_-_127674883 2.98 ENST00000507835.1
fibrillin 2
chr12_+_49297899 2.97 ENST00000552942.1
ENST00000320516.4
coiled-coil domain containing 65
chr17_+_42733803 2.94 ENST00000409122.2
chromosome 17 open reading frame 104
chr17_+_40950900 2.94 ENST00000588527.1
cyclin N-terminal domain containing 1
chr2_+_149974684 2.94 ENST00000450639.1
LY6/PLAUR domain containing 6B
chr7_+_62809239 2.94 ENST00000456890.1
AC006455.1
chr1_-_85156090 2.93 ENST00000605755.1
ENST00000437941.2
synovial sarcoma, X breakpoint 2 interacting protein
chr19_+_1104415 2.93 ENST00000585362.2
glutathione peroxidase 4
chr7_-_72742085 2.92 ENST00000333149.2
tripartite motif containing 50
chr19_+_36195467 2.90 ENST00000426659.2
zinc finger and BTB domain containing 32
chr1_-_68962744 2.88 ENST00000525124.1
DEP domain containing 1
chr11_-_68518910 2.87 ENST00000544963.1
ENST00000443940.2
metallothionein-like 5, testis-specific (tesmin)
chr9_-_127269488 2.87 ENST00000455734.1
nuclear receptor subfamily 5, group A, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MYB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.7 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
3.1 9.4 GO:0019516 lactate oxidation(GO:0019516)
2.9 11.7 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
1.7 6.9 GO:0009386 translational attenuation(GO:0009386)
1.7 5.0 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
1.6 42.2 GO:0034587 piRNA metabolic process(GO:0034587)
1.5 7.7 GO:0007538 primary sex determination(GO:0007538)
1.4 5.8 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
1.3 1.3 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
1.2 6.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
1.2 7.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
1.1 9.1 GO:0007341 penetration of zona pellucida(GO:0007341)
1.1 10.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
1.1 20.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
1.0 4.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
1.0 3.0 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
1.0 8.0 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
1.0 4.8 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.9 2.7 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.9 5.1 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.8 3.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.8 2.3 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.7 5.2 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.7 7.4 GO:0051013 microtubule severing(GO:0051013)
0.7 3.6 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.7 8.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.7 7.6 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.7 2.0 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.6 2.5 GO:0072301 negative regulation of metanephric glomerulus development(GO:0072299) regulation of metanephric glomerular mesangial cell proliferation(GO:0072301) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.6 19.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.6 1.9 GO:0035038 female pronucleus assembly(GO:0035038)
0.6 1.8 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.6 4.2 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.6 7.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.6 6.6 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.6 1.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.5 10.2 GO:0003351 epithelial cilium movement(GO:0003351)
0.5 5.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.5 2.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.5 2.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.5 1.5 GO:0001172 transcription, RNA-templated(GO:0001172)
0.5 0.5 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.5 2.4 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.4 2.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.4 2.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.4 8.2 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.4 2.4 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.4 3.2 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.4 4.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.4 1.2 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.4 9.5 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.4 1.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.4 77.7 GO:0007286 spermatid development(GO:0007286)
0.4 9.7 GO:0071397 cellular response to cholesterol(GO:0071397)
0.4 2.5 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.4 1.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.4 4.3 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.4 1.8 GO:0014735 regulation of muscle atrophy(GO:0014735) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.3 8.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.3 3.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.3 1.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3 6.5 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.3 6.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.3 1.3 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.3 1.0 GO:1900159 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.3 2.6 GO:0002326 B cell lineage commitment(GO:0002326)
0.3 2.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.3 1.8 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.3 0.6 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.3 9.0 GO:0016180 snRNA processing(GO:0016180)
0.3 1.5 GO:1902534 single-organism membrane invagination(GO:1902534)
0.3 2.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 4.4 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.3 7.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.3 0.9 GO:0072720 response to dithiothreitol(GO:0072720)
0.3 1.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.3 4.0 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.3 0.9 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.3 11.0 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.3 5.3 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.3 1.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.3 3.0 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 1.3 GO:0035617 stress granule disassembly(GO:0035617)
0.3 1.1 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.3 0.8 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.3 4.4 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.3 1.0 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.3 2.6 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.3 2.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 1.0 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.2 2.9 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 1.0 GO:0036292 DNA rewinding(GO:0036292)
0.2 4.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 0.7 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.2 1.1 GO:0061015 snRNA import into nucleus(GO:0061015)
0.2 0.9 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 1.5 GO:1904526 regulation of microtubule binding(GO:1904526)
0.2 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 10.7 GO:0035036 sperm-egg recognition(GO:0035036)
0.2 1.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.2 11.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 3.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 0.8 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.2 0.6 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.2 0.6 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.2 8.8 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.2 1.8 GO:0003341 cilium movement(GO:0003341)
0.2 0.8 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2 1.0 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.2 2.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 0.6 GO:0032053 ciliary basal body organization(GO:0032053)
0.2 0.7 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.2 0.9 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2 0.7 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.2 2.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 0.9 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.2 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 0.3 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.2 3.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.2 0.8 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.2 0.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 7.1 GO:0007099 centriole replication(GO:0007099)
0.2 1.0 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.2 4.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 1.4 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.2 0.5 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2 1.1 GO:0051697 protein delipidation(GO:0051697)
0.2 0.8 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.2 1.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 3.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.5 GO:0060591 chondroblast differentiation(GO:0060591)
0.1 0.7 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 2.6 GO:0090220 chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.1 1.9 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.3 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.6 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 2.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 2.6 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.5 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.9 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.5 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 2.1 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.8 GO:0030242 pexophagy(GO:0030242)
0.1 0.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.6 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1 4.6 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.9 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.4 GO:1901859 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.1 3.9 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 2.1 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 0.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 1.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.5 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.1 0.6 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.5 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 7.0 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 4.1 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 0.5 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.9 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.3 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.1 3.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 3.3 GO:0007340 acrosome reaction(GO:0007340)
0.1 1.7 GO:0070307 lens fiber cell development(GO:0070307)
0.1 2.1 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 6.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.4 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.1 1.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 2.4 GO:0045109 intermediate filament organization(GO:0045109)
0.1 1.3 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 12.5 GO:1904029 regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 1.1 GO:0032264 IMP salvage(GO:0032264)
0.1 0.5 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 2.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 2.1 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.1 1.5 GO:0043248 proteasome assembly(GO:0043248)
0.1 2.7 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 2.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 1.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.5 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.1 0.3 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 1.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 1.9 GO:0019054 modulation by virus of host process(GO:0019054)
0.1 1.9 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 2.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 42.7 GO:0007283 spermatogenesis(GO:0007283)
0.1 2.1 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 1.8 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 1.6 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 3.3 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 0.4 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.6 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.4 GO:1990523 bone regeneration(GO:1990523)
0.1 0.3 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 1.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 0.1 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441)
0.1 0.5 GO:0035799 ureter maturation(GO:0035799)
0.1 1.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.5 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.1 1.2 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 5.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 3.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 1.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.7 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.4 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 1.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.1 GO:2000349 negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.2 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 1.2 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.5 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 1.0 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.8 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.1 GO:0090230 regulation of centromere complex assembly(GO:0090230)
0.0 0.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 1.1 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 1.2 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.4 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.7 GO:0046851 negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.0 2.9 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 1.6 GO:0043029 T cell homeostasis(GO:0043029)
0.0 1.7 GO:0048265 response to pain(GO:0048265)
0.0 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.0 2.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 5.3 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.6 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 1.6 GO:0097503 sialylation(GO:0097503)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.9 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 1.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0070346 positive regulation of fat cell proliferation(GO:0070346) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.7 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.9 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 1.6 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.0 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger(GO:0007187)
0.0 0.2 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0 0.6 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 1.9 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 1.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:0060444 branching involved in mammary gland duct morphogenesis(GO:0060444)
0.0 2.2 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 2.6 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.8 GO:0007566 embryo implantation(GO:0007566)
0.0 0.5 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.3 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.3 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.0 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:2001020 regulation of response to DNA damage stimulus(GO:2001020)
0.0 0.0 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.3 GO:0030849 autosome(GO:0030849)
1.5 11.7 GO:0005694 chromosome(GO:0005694)
1.4 4.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.2 3.7 GO:0043159 acrosomal matrix(GO:0043159)
1.1 9.2 GO:0032133 chromosome passenger complex(GO:0032133)
1.1 11.2 GO:0036128 CatSper complex(GO:0036128)
1.1 4.4 GO:1990923 PET complex(GO:1990923)
1.1 17.2 GO:0033391 chromatoid body(GO:0033391)
1.0 5.8 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.9 14.0 GO:0001520 outer dense fiber(GO:0001520)
0.8 8.5 GO:0072687 meiotic spindle(GO:0072687)
0.8 8.5 GO:0000801 central element(GO:0000801)
0.8 3.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.7 4.3 GO:0071547 piP-body(GO:0071547)
0.7 17.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.7 2.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.7 2.6 GO:0035841 new growing cell tip(GO:0035841)
0.6 28.4 GO:0000795 synaptonemal complex(GO:0000795)
0.6 1.9 GO:0033011 perinuclear theca(GO:0033011)
0.6 8.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.6 1.8 GO:0001534 radial spoke(GO:0001534)
0.6 9.0 GO:0032039 integrator complex(GO:0032039)
0.5 3.2 GO:0098536 deuterosome(GO:0098536)
0.4 1.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.4 1.8 GO:1990423 RZZ complex(GO:1990423)
0.4 4.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.4 4.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.4 4.8 GO:0097255 R2TP complex(GO:0097255)
0.4 2.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.4 2.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.4 4.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.4 14.8 GO:0034451 centriolar satellite(GO:0034451)
0.3 8.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.3 7.5 GO:0097225 sperm midpiece(GO:0097225)
0.3 2.2 GO:0000796 condensin complex(GO:0000796)
0.3 2.4 GO:0002177 manchette(GO:0002177)
0.3 3.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.3 4.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 3.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.3 4.8 GO:0045179 apical cortex(GO:0045179)
0.3 0.8 GO:0042565 RNA nuclear export complex(GO:0042565)
0.2 8.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 5.0 GO:0005858 axonemal dynein complex(GO:0005858)
0.2 9.1 GO:0002080 acrosomal membrane(GO:0002080)
0.2 0.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 0.5 GO:0005879 axonemal microtubule(GO:0005879)
0.2 2.7 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 0.9 GO:0032449 CBM complex(GO:0032449)
0.2 0.8 GO:0032389 MutLalpha complex(GO:0032389)
0.2 0.5 GO:0034515 proteasome storage granule(GO:0034515)
0.2 22.2 GO:0031514 motile cilium(GO:0031514)
0.2 2.8 GO:0000812 Swr1 complex(GO:0000812)
0.2 6.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 1.6 GO:0005638 lamin filament(GO:0005638)
0.2 0.5 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.2 21.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.2 2.1 GO:0061700 GATOR2 complex(GO:0061700)
0.2 6.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 17.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 6.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.0 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 4.3 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 1.3 GO:0005827 polar microtubule(GO:0005827)
0.1 12.3 GO:0036064 ciliary basal body(GO:0036064)
0.1 1.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.9 GO:0031415 NatA complex(GO:0031415)
0.1 3.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 10.3 GO:0005814 centriole(GO:0005814)
0.1 0.6 GO:0005927 muscle tendon junction(GO:0005927)
0.1 1.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 3.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.5 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 3.1 GO:0042101 T cell receptor complex(GO:0042101)
0.1 4.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 2.0 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 2.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 4.5 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 2.0 GO:0070822 Sin3-type complex(GO:0070822)
0.1 7.6 GO:0005901 caveola(GO:0005901)
0.1 0.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 11.4 GO:0005882 intermediate filament(GO:0005882)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 12.0 GO:0001650 fibrillar center(GO:0001650)
0.0 2.1 GO:0099738 cell cortex region(GO:0099738)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.9 GO:0016592 mediator complex(GO:0016592)
0.0 4.9 GO:0016605 PML body(GO:0016605)
0.0 1.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 2.2 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 16.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 1.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.6 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 2.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0031672 A band(GO:0031672)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 3.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.0 GO:0071564 npBAF complex(GO:0071564)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.4 GO:0031201 SNARE complex(GO:0031201)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 2.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 3.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.4 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.3 GO:0030286 dynein complex(GO:0030286)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 27.4 GO:0004000 adenosine deaminase activity(GO:0004000)
1.0 4.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.0 10.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.0 5.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
1.0 4.0 GO:0004040 amidase activity(GO:0004040)
1.0 2.9 GO:0004103 choline kinase activity(GO:0004103)
0.9 7.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.7 6.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.7 6.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.6 4.8 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.6 3.0 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.6 3.5 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.5 18.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.5 2.7 GO:0031208 POZ domain binding(GO:0031208)
0.5 2.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.5 25.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.5 2.0 GO:0035501 MH1 domain binding(GO:0035501)
0.5 2.0 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.5 1.5 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.5 3.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.5 1.8 GO:0001601 peptide YY receptor activity(GO:0001601)
0.4 7.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.4 2.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.4 1.2 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.4 5.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.4 14.3 GO:0008143 poly(A) binding(GO:0008143)
0.3 1.4 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.3 3.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.3 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 1.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.3 2.7 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.3 3.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 0.9 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.3 1.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.3 0.8 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.2 4.6 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 11.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 2.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 11.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 0.9 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 7.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 1.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 0.6 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.2 11.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.2 10.0 GO:0070840 dynein complex binding(GO:0070840)
0.2 2.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.5 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.2 0.7 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.2 6.6 GO:0008171 O-methyltransferase activity(GO:0008171)
0.2 2.9 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 2.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 13.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 0.7 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.2 2.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 5.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 0.5 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 0.8 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.2 10.1 GO:0050699 WW domain binding(GO:0050699)
0.1 2.8 GO:0048185 activin binding(GO:0048185)
0.1 1.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 2.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 4.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 23.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 1.3 GO:0035197 siRNA binding(GO:0035197)
0.1 2.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.5 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 2.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 5.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.6 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 1.8 GO:0019864 IgG binding(GO:0019864)
0.1 11.6 GO:0008565 protein transporter activity(GO:0008565)
0.1 0.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 8.8 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.9 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.1 GO:0043422 protein kinase B binding(GO:0043422)
0.1 3.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 7.9 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 9.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 1.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.9 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 3.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.8 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.1 4.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 1.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 2.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 6.0 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.3 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 8.6 GO:0051087 chaperone binding(GO:0051087)
0.1 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 2.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.8 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 2.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 3.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 1.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 2.0 GO:0005549 odorant binding(GO:0005549)
0.0 0.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 1.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.1 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 3.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 2.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 3.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 10.7 GO:0005125 cytokine activity(GO:0005125)
0.0 1.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 5.3 GO:0005262 calcium channel activity(GO:0005262)
0.0 23.1 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.0 2.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 30.5 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 1.0 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 3.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 2.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 3.4 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 2.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 11.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.8 GO:0004386 helicase activity(GO:0004386)
0.0 2.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.4 GO:0042393 histone binding(GO:0042393)
0.0 0.9 GO:0019213 deacetylase activity(GO:0019213)
0.0 13.1 GO:0008270 zinc ion binding(GO:0008270)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 33.4 PID PLK1 PATHWAY PLK1 signaling events
0.3 19.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 16.6 PID AURORA B PATHWAY Aurora B signaling
0.1 7.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 3.8 PID MYC PATHWAY C-MYC pathway
0.1 5.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 11.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 3.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 5.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 3.6 PID P73PATHWAY p73 transcription factor network
0.0 2.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.4 7.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.3 5.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3 10.6 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2 25.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 5.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 25.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 7.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.2 0.6 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.2 2.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 4.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 3.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 4.4 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.1 0.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 2.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 4.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 3.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 2.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 5.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 3.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 2.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.6 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.4 REACTOME KINESINS Genes involved in Kinesins
0.0 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.2 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 9.3 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.6 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.3 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 2.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects