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Illumina Body Map 2, young vs old

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Results for NFAT5

Z-value: 0.32

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Transcription factors associated with NFAT5

Gene Symbol Gene ID Gene Info
NFAT5
ENSG00000102908.16 nuclear factor of activated T cells 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFAT5hg19_v2_chr16_+_69599899_695999650.621.6e-04Click!

Activity profile of NFAT5 motif

Sorted Z-values of NFAT5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_101988627 2.97 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr12_+_101988774 2.60 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr11_+_131240373 2.49 ENST00000374791.3
ENST00000436745.1
NTM
neurotrimin
chr15_+_43885252 2.36 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr15_+_43985725 2.31 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr15_+_43985084 2.20 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr11_+_131240593 2.06 ENST00000539799.1
NTM
neurotrimin
chr6_+_160327974 2.05 ENST00000252660.4
MAS1
MAS1 oncogene
chr11_+_73359719 1.98 ENST00000535129.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr13_-_67804445 1.98 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
PCDH9
protocadherin 9
chr22_-_38380543 1.87 ENST00000396884.2
SOX10
SRY (sex determining region Y)-box 10
chr14_-_60097524 1.84 ENST00000342503.4
RTN1
reticulon 1
chr11_+_131781290 1.84 ENST00000425719.2
ENST00000374784.1
NTM
neurotrimin
chr15_-_49170219 1.70 ENST00000558220.1
ENST00000537958.1
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr15_+_54901540 1.69 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr6_+_150464155 1.67 ENST00000361131.4
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr14_-_60097297 1.55 ENST00000395090.1
RTN1
reticulon 1
chr15_+_54793169 1.50 ENST00000559093.1
UNC13C
unc-13 homolog C (C. elegans)
chr11_-_111794446 1.45 ENST00000527950.1
CRYAB
crystallin, alpha B
chr6_+_73331776 1.44 ENST00000370398.1
KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr12_-_75603643 1.40 ENST00000549446.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr12_-_75603482 1.38 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr7_+_95401851 1.36 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr7_+_30174574 1.30 ENST00000409688.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr5_+_140186647 1.29 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chr12_-_55375622 1.28 ENST00000316577.8
TESPA1
thymocyte expressed, positive selection associated 1
chr3_-_116163830 1.28 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr12_+_26274917 1.16 ENST00000538142.1
SSPN
sarcospan
chr7_+_95401877 1.15 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr6_+_153071925 1.13 ENST00000367244.3
ENST00000367243.3
VIP
vasoactive intestinal peptide
chr5_-_78808617 1.11 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chr11_+_56949221 1.10 ENST00000497933.1
LRRC55
leucine rich repeat containing 55
chr3_+_63805017 1.04 ENST00000295896.8
C3orf49
chromosome 3 open reading frame 49
chr16_+_89988259 0.97 ENST00000554444.1
ENST00000556565.1
TUBB3
Tubulin beta-3 chain
chr20_-_62103862 0.96 ENST00000344462.4
ENST00000357249.2
ENST00000359125.2
ENST00000360480.3
ENST00000370224.1
ENST00000344425.5
ENST00000354587.3
ENST00000359689.1
KCNQ2
potassium voltage-gated channel, KQT-like subfamily, member 2
chr1_+_95975672 0.94 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr1_+_18958008 0.92 ENST00000420770.2
ENST00000400661.3
PAX7
paired box 7
chr11_-_8190534 0.92 ENST00000309737.6
ENST00000425599.2
ENST00000539720.1
ENST00000531450.1
ENST00000419822.2
ENST00000335425.7
ENST00000343202.4
RIC3
RIC3 acetylcholine receptor chaperone
chr6_+_73331814 0.91 ENST00000370392.1
KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr5_+_140261703 0.86 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr8_+_50824233 0.84 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr12_-_100378392 0.83 ENST00000549866.1
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_+_111888890 0.83 ENST00000369738.4
PIFO
primary cilia formation
chr15_+_43885799 0.82 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr1_+_111889212 0.81 ENST00000369737.4
PIFO
primary cilia formation
chr12_-_55367331 0.81 ENST00000526532.1
ENST00000532757.1
TESPA1
thymocyte expressed, positive selection associated 1
chr1_-_248845629 0.81 ENST00000342623.3
OR14I1
olfactory receptor, family 14, subfamily I, member 1
chrX_-_70150939 0.79 ENST00000374299.3
ENST00000298085.4
SLC7A3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr10_-_69455873 0.79 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr17_+_68071389 0.77 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr14_-_25479811 0.76 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr17_+_68071458 0.74 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr11_-_58612168 0.74 ENST00000287275.1
GLYATL2
glycine-N-acyltransferase-like 2
chr2_-_161056802 0.72 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr17_-_37764128 0.71 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chrX_+_18725758 0.71 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr7_-_123673471 0.71 ENST00000455783.1
TMEM229A
transmembrane protein 229A
chrX_+_37208540 0.70 ENST00000466533.1
ENST00000542554.1
ENST00000543642.1
ENST00000484460.1
ENST00000449135.2
ENST00000463135.1
ENST00000465127.1
PRRG1
TM4SF2
proline rich Gla (G-carboxyglutamic acid) 1
Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7
chr12_+_10365082 0.70 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr1_+_159174701 0.69 ENST00000435307.1
DARC
Duffy blood group, atypical chemokine receptor
chrX_+_37208521 0.69 ENST00000378628.4
PRRG1
proline rich Gla (G-carboxyglutamic acid) 1
chr1_+_201592013 0.69 ENST00000593583.1
AC096677.1
Uncharacterized protein ENSP00000471857
chr1_+_34632484 0.69 ENST00000373374.3
C1orf94
chromosome 1 open reading frame 94
chr7_-_71868354 0.67 ENST00000412588.1
CALN1
calneuron 1
chrX_-_130964596 0.66 ENST00000427391.1
RP11-453F18__B.1
RP11-453F18__B.1
chr5_-_96209315 0.66 ENST00000504056.1
CTD-2260A17.2
Uncharacterized protein
chr6_-_44400720 0.65 ENST00000595057.1
AL133262.1
AL133262.1
chr2_-_67442409 0.64 ENST00000414404.1
ENST00000433133.1
AC078941.1
AC078941.1
chr1_-_201346761 0.63 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
TNNT2
troponin T type 2 (cardiac)
chr12_+_10365404 0.62 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr1_-_60539422 0.61 ENST00000371201.3
C1orf87
chromosome 1 open reading frame 87
chr20_+_33104199 0.60 ENST00000357156.2
ENST00000417166.2
ENST00000300469.9
ENST00000374846.3
DYNLRB1
dynein, light chain, roadblock-type 1
chr7_+_147830776 0.59 ENST00000538075.1
CNTNAP2
contactin associated protein-like 2
chr12_+_122018697 0.58 ENST00000541574.1
RP13-941N14.1
RP13-941N14.1
chr4_+_71587669 0.58 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr7_+_149570049 0.56 ENST00000421974.2
ENST00000456496.2
ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr14_+_97059070 0.55 ENST00000553378.1
ENST00000555496.1
RP11-433J8.1
RP11-433J8.1
chr13_-_30160925 0.54 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr15_+_49170281 0.54 ENST00000560490.1
EID1
EP300 interacting inhibitor of differentiation 1
chr2_-_20101385 0.54 ENST00000431392.1
TTC32
tetratricopeptide repeat domain 32
chr4_+_122685691 0.53 ENST00000424958.1
AC079341.1
Uncharacterized protein
chr9_+_114287433 0.52 ENST00000358151.4
ENST00000355824.3
ENST00000374374.3
ENST00000309235.5
ZNF483
zinc finger protein 483
chr3_-_47950745 0.52 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr8_-_103251102 0.52 ENST00000519962.1
ENST00000519317.1
ENST00000395912.2
RRM2B
ribonucleotide reductase M2 B (TP53 inducible)
chr7_+_96634850 0.52 ENST00000518156.2
DLX6
distal-less homeobox 6
chr2_-_161056762 0.50 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr8_-_27469196 0.49 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr3_-_108248169 0.49 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr1_-_60539405 0.48 ENST00000450089.2
C1orf87
chromosome 1 open reading frame 87
chr18_-_33702078 0.48 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr3_+_177159744 0.48 ENST00000439009.1
LINC00578
long intergenic non-protein coding RNA 578
chrX_+_135579670 0.47 ENST00000218364.4
HTATSF1
HIV-1 Tat specific factor 1
chr8_-_103250997 0.47 ENST00000522368.1
RRM2B
ribonucleotide reductase M2 B (TP53 inducible)
chr12_+_119772502 0.47 ENST00000536742.1
ENST00000327554.2
CCDC60
coiled-coil domain containing 60
chr10_-_124639062 0.46 ENST00000368898.3
ENST00000368896.1
ENST00000545804.1
FAM24B
CUZD1
family with sequence similarity 24, member B
CUB and zona pellucida-like domains 1
chr8_-_27469383 0.46 ENST00000519742.1
CLU
clusterin
chr9_-_80263220 0.45 ENST00000341700.6
GNA14
guanine nucleotide binding protein (G protein), alpha 14
chr19_+_17420340 0.45 ENST00000359866.4
DDA1
DET1 and DDB1 associated 1
chr4_-_83483360 0.44 ENST00000449862.2
TMEM150C
transmembrane protein 150C
chr2_+_108994466 0.42 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr4_+_71588372 0.42 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr11_+_60635035 0.41 ENST00000278853.5
ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr3_+_77088989 0.40 ENST00000461745.1
ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr17_+_9745786 0.39 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr1_-_246670519 0.39 ENST00000388985.4
ENST00000490107.1
SMYD3
SET and MYND domain containing 3
chr3_-_18487057 0.39 ENST00000415069.1
SATB1
SATB homeobox 1
chr17_+_32646055 0.38 ENST00000394620.1
CCL8
chemokine (C-C motif) ligand 8
chr5_+_156712372 0.38 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr7_+_120969045 0.37 ENST00000222462.2
WNT16
wingless-type MMTV integration site family, member 16
chr9_-_34589700 0.37 ENST00000351266.4
CNTFR
ciliary neurotrophic factor receptor
chr3_+_49027308 0.37 ENST00000383729.4
ENST00000343546.4
P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr1_+_36789335 0.36 ENST00000373137.2
RP11-268J15.5
RP11-268J15.5
chr7_-_92855762 0.36 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr4_-_83483395 0.36 ENST00000515780.2
TMEM150C
transmembrane protein 150C
chr12_+_69186125 0.36 ENST00000399333.3
AC124890.1
HCG1774533, isoform CRA_a; PRO2268; Uncharacterized protein
chr6_+_116832789 0.36 ENST00000368599.3
FAM26E
family with sequence similarity 26, member E
chr1_+_209602771 0.36 ENST00000440276.1
MIR205HG
MIR205 host gene (non-protein coding)
chr18_-_74839891 0.36 ENST00000581878.1
MBP
myelin basic protein
chr6_-_53530474 0.35 ENST00000370905.3
KLHL31
kelch-like family member 31
chr1_-_243417762 0.35 ENST00000522191.1
CEP170
centrosomal protein 170kDa
chr11_-_56258871 0.35 ENST00000327216.2
OR5M8
olfactory receptor, family 5, subfamily M, member 8
chr9_+_139702363 0.34 ENST00000371663.4
ENST00000371671.4
ENST00000311502.7
RABL6
RAB, member RAS oncogene family-like 6
chr7_+_141478242 0.33 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chr5_-_77844974 0.33 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr15_+_49170083 0.31 ENST00000530028.2
EID1
EP300 interacting inhibitor of differentiation 1
chr2_+_48796120 0.30 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr14_-_30396948 0.29 ENST00000331968.5
PRKD1
protein kinase D1
chr12_+_69139886 0.29 ENST00000398004.2
SLC35E3
solute carrier family 35, member E3
chr1_-_115300579 0.29 ENST00000358528.4
ENST00000525132.1
CSDE1
cold shock domain containing E1, RNA-binding
chr11_+_392587 0.28 ENST00000534401.1
PKP3
plakophilin 3
chr17_+_25799008 0.28 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr19_-_54876414 0.28 ENST00000474878.1
ENST00000348231.4
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr8_+_132320792 0.27 ENST00000519695.1
ENST00000524275.1
CTD-2501M5.1
CTD-2501M5.1
chr4_+_26322409 0.27 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr15_+_45028719 0.27 ENST00000560442.1
ENST00000558329.1
ENST00000561043.1
TRIM69
tripartite motif containing 69
chr15_+_45028753 0.26 ENST00000338264.4
TRIM69
tripartite motif containing 69
chr19_+_42212526 0.26 ENST00000598976.1
ENST00000435837.2
ENST00000221992.6
ENST00000405816.1
CEA
CEACAM5
Uncharacterized protein
carcinoembryonic antigen-related cell adhesion molecule 5
chr2_+_56179262 0.26 ENST00000606639.1
RP11-481J13.1
RP11-481J13.1
chr1_-_115300592 0.25 ENST00000261443.5
ENST00000534699.1
ENST00000339438.6
ENST00000529046.1
ENST00000525970.1
ENST00000369530.1
ENST00000530886.1
CSDE1
cold shock domain containing E1, RNA-binding
chr1_-_246670614 0.25 ENST00000403792.3
SMYD3
SET and MYND domain containing 3
chr2_+_47799601 0.25 ENST00000601243.1
AC138655.1
CDNA: FLJ23120 fis, clone LNG07989; HCG1987724; Uncharacterized protein
chr16_-_65268795 0.24 ENST00000565901.1
ENST00000567058.1
RP11-256I9.2
RP11-256I9.2
chr2_-_223163465 0.24 ENST00000409828.3
ENST00000350526.4
ENST00000258387.5
ENST00000409551.3
ENST00000392069.2
ENST00000344493.4
ENST00000336840.6
ENST00000392070.2
PAX3
paired box 3
chr1_-_243418344 0.24 ENST00000366542.1
CEP170
centrosomal protein 170kDa
chr5_+_150591678 0.23 ENST00000523466.1
GM2A
GM2 ganglioside activator
chr22_-_44208070 0.23 ENST00000396231.2
EFCAB6
EF-hand calcium binding domain 6
chr1_+_248058889 0.23 ENST00000360358.3
OR2W3
olfactory receptor, family 2, subfamily W, member 3
chr3_-_48594248 0.23 ENST00000545984.1
ENST00000232375.3
ENST00000416568.1
ENST00000383734.2
ENST00000541519.1
ENST00000412035.1
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr16_+_68573116 0.22 ENST00000570495.1
ENST00000563169.2
ENST00000564323.1
ENST00000562156.1
ENST00000573685.1
ZFP90
ZFP90 zinc finger protein
chr9_+_95909309 0.22 ENST00000366188.2
RP11-370F5.4
RP11-370F5.4
chr7_-_100888337 0.22 ENST00000223136.4
FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr3_+_8543393 0.21 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr8_-_7243080 0.21 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr17_+_40950900 0.20 ENST00000588527.1
CNTD1
cyclin N-terminal domain containing 1
chr3_+_8543533 0.20 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr7_-_100888313 0.20 ENST00000442303.1
FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr14_+_100240019 0.20 ENST00000556199.1
EML1
echinoderm microtubule associated protein like 1
chr3_+_185000729 0.19 ENST00000448876.1
ENST00000446828.1
ENST00000447637.1
ENST00000424227.1
ENST00000454237.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr16_-_67514982 0.19 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr19_-_54876558 0.18 ENST00000391742.2
ENST00000434277.2
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr12_+_99038998 0.18 ENST00000359972.2
ENST00000357310.1
ENST00000339433.3
ENST00000333991.1
APAF1
apoptotic peptidase activating factor 1
chr16_-_85969774 0.18 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr14_-_103589246 0.17 ENST00000558224.1
ENST00000560742.1
LINC00677
long intergenic non-protein coding RNA 677
chr4_+_26322185 0.17 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr10_-_118928543 0.17 ENST00000419373.2
RP11-501J20.2
RP11-501J20.2
chr3_+_8543561 0.17 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr9_-_6015607 0.16 ENST00000259569.5
RANBP6
RAN binding protein 6
chr6_-_29324054 0.16 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr14_+_91580732 0.16 ENST00000519019.1
ENST00000523816.1
ENST00000517518.1
C14orf159
chromosome 14 open reading frame 159
chr11_+_19799327 0.15 ENST00000540292.1
NAV2
neuron navigator 2
chr17_+_38083977 0.15 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
RP11-387H17.4
chr6_-_131291572 0.15 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr6_+_153552455 0.15 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr12_-_82152444 0.15 ENST00000549325.1
ENST00000550584.2
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr3_+_69811858 0.15 ENST00000433517.1
MITF
microphthalmia-associated transcription factor
chr5_-_137090028 0.15 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr7_-_19184929 0.15 ENST00000275461.3
FERD3L
Fer3-like bHLH transcription factor
chr9_+_125376948 0.14 ENST00000297913.2
OR1Q1
olfactory receptor, family 1, subfamily Q, member 1
chr14_-_102706934 0.14 ENST00000523231.1
ENST00000524370.1
ENST00000517966.1
MOK
MOK protein kinase
chr19_-_46285736 0.14 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK
dystrophia myotonica-protein kinase
chr14_+_91580357 0.14 ENST00000298858.4
ENST00000521081.1
ENST00000520328.1
ENST00000256324.10
ENST00000524232.1
ENST00000522170.1
ENST00000519950.1
ENST00000523879.1
ENST00000521077.2
ENST00000518665.2
C14orf159
chromosome 14 open reading frame 159
chr19_+_42212501 0.14 ENST00000398599.4
CEACAM5
carcinoembryonic antigen-related cell adhesion molecule 5
chr4_-_83483094 0.13 ENST00000508701.1
ENST00000454948.3
TMEM150C
transmembrane protein 150C
chr2_+_233924548 0.13 ENST00000422935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr2_-_200820459 0.12 ENST00000354611.4
TYW5
tRNA-yW synthesizing protein 5
chr20_-_23731893 0.12 ENST00000398402.1
CST1
cystatin SN
chr2_+_201390843 0.12 ENST00000357799.4
ENST00000409203.3
SGOL2
shugoshin-like 2 (S. pombe)
chrX_+_107037451 0.11 ENST00000372379.2
NCBP2L
nuclear cap binding protein subunit 2-like
chr12_-_10955226 0.10 ENST00000240687.2
TAS2R7
taste receptor, type 2, member 7
chr3_+_9834758 0.10 ENST00000485273.1
ENST00000433034.1
ENST00000397256.1
ARPC4
ARPC4-TTLL3
actin related protein 2/3 complex, subunit 4, 20kDa
ARPC4-TTLL3 readthrough
chr11_-_4881794 0.10 ENST00000322059.1
OR51H1P
olfactory receptor, family 51, subfamily H, member 1 pseudogene
chr11_-_77705687 0.10 ENST00000529807.1
ENST00000527522.1
ENST00000534064.1
INTS4
integrator complex subunit 4
chr11_-_7950209 0.10 ENST00000309838.2
OR10A6
olfactory receptor, family 10, subfamily A, member 6
chr14_+_73704201 0.10 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr4_+_17578815 0.09 ENST00000226299.4
LAP3
leucine aminopeptidase 3
chr7_-_92157760 0.09 ENST00000248633.4
PEX1
peroxisomal biogenesis factor 1
chr4_+_17579110 0.09 ENST00000606142.1
LAP3
leucine aminopeptidase 3
chr14_+_91580777 0.09 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
C14orf159
chromosome 14 open reading frame 159
chr19_-_12792020 0.08 ENST00000594424.1
ENST00000597152.1
ENST00000596162.1
DHPS
deoxyhypusine synthase
chr6_-_10415218 0.08 ENST00000466073.1
ENST00000498450.1
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

Network of associatons between targets according to the STRING database.

First level regulatory network of NFAT5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.3 2.8 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.3 3.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 2.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.3 1.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.3 4.5 GO:0006600 creatine metabolic process(GO:0006600)
0.3 5.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 2.5 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.6 GO:0071109 superior temporal gyrus development(GO:0071109)
0.2 0.6 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 1.3 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 2.0 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 1.0 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.8 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 1.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.9 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 6.8 GO:0008038 neuron recognition(GO:0008038)
0.1 0.4 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 1.1 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.4 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 1.1 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.8 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.4 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 1.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.0 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 1.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.4 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.4 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.3 GO:1901727 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 2.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 1.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.7 GO:0007035 vacuolar acidification(GO:0007035)
0.0 1.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 3.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.9 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 1.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 1.2 GO:0006936 muscle contraction(GO:0006936)
0.0 3.1 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.6 GO:0014904 myotube cell development(GO:0014904)
0.0 0.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 3.2 GO:0044305 calyx of Held(GO:0044305)
0.2 6.1 GO:0032982 myosin filament(GO:0032982)
0.1 2.1 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 3.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.7 GO:0042025 host cell nucleus(GO:0042025)
0.1 0.4 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.8 GO:0016013 syntrophin complex(GO:0016013)
0.1 3.8 GO:0030673 axolemma(GO:0030673)
0.1 1.0 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0043293 apoptosome(GO:0043293)
0.0 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 1.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 5.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.9 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 2.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 6.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0005686 U2 snRNP(GO:0005686)
0.0 2.0 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 2.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.9 GO:0015030 Cajal body(GO:0015030)
0.0 1.5 GO:0036064 ciliary basal body(GO:0036064)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.5 GO:0004111 creatine kinase activity(GO:0004111)
0.3 2.0 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.3 0.8 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.2 5.6 GO:0031432 titin binding(GO:0031432)
0.1 1.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 1.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 2.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.4 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 3.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.7 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 2.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.6 GO:0030172 troponin C binding(GO:0030172)
0.1 1.3 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.5 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 1.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.8 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 1.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 4.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.4 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.4 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 1.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.6 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.2 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 1.0 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 1.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0031418 L-ascorbic acid binding(GO:0031418)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.6 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 6.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.5 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 5.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane