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Illumina Body Map 2, young vs old

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Results for NFATC2_NFATC3

Z-value: 0.41

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Transcription factors associated with NFATC2_NFATC3

Gene Symbol Gene ID Gene Info
ENSG00000101096.15 nuclear factor of activated T cells 2
ENSG00000072736.14 nuclear factor of activated T cells 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC2hg19_v2_chr20_-_50179368_50179392-0.459.1e-03Click!
NFATC3hg19_v2_chr16_+_68119247_68119293-0.212.5e-01Click!

Activity profile of NFATC2_NFATC3 motif

Sorted Z-values of NFATC2_NFATC3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_100565249 10.63 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI family, member 3 (NESH) binding protein
chr12_-_91573249 7.52 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr14_-_92413353 6.47 ENST00000556154.1
fibulin 5
chr14_+_24837226 6.38 ENST00000554050.1
ENST00000554903.1
ENST00000554779.1
ENST00000250373.4
ENST00000553708.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr17_+_59477233 6.33 ENST00000240328.3
T-box 2
chr12_-_91573132 6.29 ENST00000550563.1
ENST00000546370.1
decorin
chr12_-_91573316 5.81 ENST00000393155.1
decorin
chr1_+_86046433 5.67 ENST00000451137.2
cysteine-rich, angiogenic inducer, 61
chr15_+_45722727 5.62 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
chromosome 15 open reading frame 48
chr15_+_96869165 5.52 ENST00000421109.2
nuclear receptor subfamily 2, group F, member 2
chr15_-_65503801 5.51 ENST00000261883.4
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr11_+_101983176 5.47 ENST00000524575.1
Yes-associated protein 1
chr1_+_46640750 5.42 ENST00000372003.1
tetraspanin 1
chr9_-_35691017 5.41 ENST00000378292.3
tropomyosin 2 (beta)
chr11_-_10590238 5.26 ENST00000256178.3
lymphatic vessel endothelial hyaluronan receptor 1
chr3_-_112360116 5.12 ENST00000206423.3
ENST00000439685.2
coiled-coil domain containing 80
chr12_+_54393880 5.00 ENST00000303450.4
homeobox C9
chr11_-_10590118 4.63 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr11_-_68780824 4.59 ENST00000441623.1
ENST00000309099.6
MAS-related GPR, member F
chr8_-_23712312 4.43 ENST00000290271.2
stanniocalcin 1
chr12_-_7244469 4.22 ENST00000538050.1
ENST00000536053.2
complement component 1, r subcomponent
chr14_-_92413727 4.19 ENST00000267620.10
fibulin 5
chr2_-_163099885 4.16 ENST00000443424.1
fibroblast activation protein, alpha
chr17_-_74528128 4.13 ENST00000590175.1
cytoglobin
chr11_-_123065989 4.06 ENST00000448775.2
CXADR-like membrane protein
chr2_-_190044480 4.05 ENST00000374866.3
collagen, type V, alpha 2
chr2_-_163100045 4.05 ENST00000188790.4
fibroblast activation protein, alpha
chr16_-_66952779 4.03 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
cadherin 16, KSP-cadherin
chr17_-_36105009 3.91 ENST00000560016.1
ENST00000427275.2
ENST00000561193.1
HNF1 homeobox B
chr8_+_70404996 3.86 ENST00000402687.4
ENST00000419716.3
sulfatase 1
chr2_+_177028805 3.67 ENST00000249440.3
homeobox D3
chr8_+_98900132 3.64 ENST00000520016.1
matrilin 2
chr8_-_95274536 3.63 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr8_+_102504979 3.57 ENST00000395927.1
grainyhead-like 2 (Drosophila)
chr15_-_37391614 3.40 ENST00000219869.9
Meis homeobox 2
chr15_-_37391507 3.39 ENST00000557796.2
ENST00000397620.2
Meis homeobox 2
chr2_-_238322770 3.34 ENST00000472056.1
collagen, type VI, alpha 3
chr16_+_66400533 3.31 ENST00000341529.3
cadherin 5, type 2 (vascular endothelium)
chr16_-_66952742 3.26 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
cadherin 16, KSP-cadherin
chr12_-_9268707 3.25 ENST00000318602.7
alpha-2-macroglobulin
chr12_+_50344516 3.25 ENST00000199280.3
ENST00000550862.1
aquaporin 2 (collecting duct)
chr15_-_37392086 3.21 ENST00000561208.1
Meis homeobox 2
chr8_-_13134045 3.20 ENST00000512044.2
deleted in liver cancer 1
chr1_+_170632250 3.17 ENST00000367760.3
paired related homeobox 1
chr3_+_99357319 3.16 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
collagen, type VIII, alpha 1
chr2_-_238322800 3.15 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
collagen, type VI, alpha 3
chr11_-_119293872 3.15 ENST00000524970.1
Thy-1 cell surface antigen
chr9_+_35806082 3.09 ENST00000447210.1
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr6_+_152011628 3.08 ENST00000404742.1
ENST00000440973.1
estrogen receptor 1
chr21_+_27011584 3.07 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
junctional adhesion molecule 2
chr1_-_178838404 3.05 ENST00000444255.1
angiopoietin-like 1
chr17_-_1389228 3.02 ENST00000438665.2
myosin IC
chr1_+_209602771 2.93 ENST00000440276.1
MIR205 host gene (non-protein coding)
chr17_-_1389419 2.93 ENST00000575158.1
myosin IC
chr5_+_140514782 2.92 ENST00000231134.5
protocadherin beta 5
chr2_-_238323007 2.90 ENST00000295550.4
collagen, type VI, alpha 3
chr5_+_140480083 2.90 ENST00000231130.2
protocadherin beta 3
chr1_+_38022513 2.90 ENST00000296218.7
dynein, axonemal, light intermediate chain 1
chr3_+_148447887 2.84 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
angiotensin II receptor, type 1
chr17_-_46688334 2.79 ENST00000239165.7
homeobox B7
chr4_-_87770416 2.77 ENST00000273905.6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr1_+_153651078 2.76 ENST00000368680.3
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr9_-_13165457 2.72 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
multiple PDZ domain protein
chr2_-_163099546 2.70 ENST00000447386.1
fibroblast activation protein, alpha
chr3_+_25469724 2.69 ENST00000437042.2
retinoic acid receptor, beta
chr1_+_38022572 2.69 ENST00000541606.1
dynein, axonemal, light intermediate chain 1
chr2_+_48796120 2.67 ENST00000394754.1
STON1-GTF2A1L readthrough
chrX_+_105192423 2.65 ENST00000540278.1
Nik related kinase
chr11_+_34654011 2.64 ENST00000531794.1
ets homologous factor
chr1_+_162602244 2.64 ENST00000367922.3
ENST00000367921.3
discoidin domain receptor tyrosine kinase 2
chr2_-_42160486 2.63 ENST00000427054.1
AC104654.2
chr7_+_134551583 2.57 ENST00000435928.1
caldesmon 1
chrX_-_154255143 2.56 ENST00000453950.1
ENST00000423959.1
coagulation factor VIII, procoagulant component
chr2_+_176994408 2.56 ENST00000429017.1
ENST00000313173.4
ENST00000544999.1
homeobox D8
chr8_-_81787006 2.54 ENST00000327835.3
zinc finger protein 704
chr19_+_11658655 2.50 ENST00000588935.1
calponin 1, basic, smooth muscle
chr11_-_119187826 2.49 ENST00000264036.4
melanoma cell adhesion molecule
chr13_+_37247934 2.49 ENST00000315190.3
serine-rich and transmembrane domain containing 1
chr12_-_9268819 2.48 ENST00000404455.2
alpha-2-macroglobulin
chr1_-_153538011 2.47 ENST00000368707.4
S100 calcium binding protein A2
chr11_-_102401469 2.45 ENST00000260227.4
matrix metallopeptidase 7 (matrilysin, uterine)
chr2_+_234580525 2.45 ENST00000609637.1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr17_-_46657473 2.44 ENST00000332503.5
homeobox B4
chr11_-_85397167 2.44 ENST00000316398.3
coiled-coil domain containing 89
chr5_+_140186647 2.43 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
protocadherin alpha 4
chr10_+_128593978 2.43 ENST00000280333.6
dedicator of cytokinesis 1
chr3_-_195310802 2.42 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr1_+_82266053 2.41 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
latrophilin 2
chr6_-_41715128 2.41 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
progastricsin (pepsinogen C)
chr15_+_43885252 2.40 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
creatine kinase, mitochondrial 1B
chr15_-_68724490 2.40 ENST00000315757.7
ENST00000423218.2
integrin, alpha 11
chr6_+_127439749 2.39 ENST00000356698.4
R-spondin 3
chr4_+_41258786 2.36 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chrX_+_102585124 2.33 ENST00000332431.4
ENST00000372666.1
transcription elongation factor A (SII)-like 7
chr11_+_65190245 2.31 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr14_+_63671105 2.31 ENST00000316754.3
ras homolog family member J
chr17_-_53800217 2.29 ENST00000424486.2
transmembrane protein 100
chr1_-_150780757 2.29 ENST00000271651.3
cathepsin K
chr18_-_47376197 2.29 ENST00000592688.1
myosin VB
chr5_+_140174429 2.28 ENST00000520672.2
ENST00000378132.1
ENST00000526136.1
protocadherin alpha 2
chr9_-_13175823 2.24 ENST00000545857.1
multiple PDZ domain protein
chr12_-_91539918 2.23 ENST00000548218.1
decorin
chr8_+_106331769 2.23 ENST00000520492.1
zinc finger protein, FOG family member 2
chr5_-_158526756 2.23 ENST00000313708.6
ENST00000517373.1
early B-cell factor 1
chr3_-_134092561 2.21 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
angiomotin like 2
chr17_-_39041479 2.20 ENST00000167588.3
keratin 20
chr4_-_100212132 2.18 ENST00000209668.2
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr7_+_20687017 2.17 ENST00000258738.6
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr16_+_31483451 2.13 ENST00000565360.1
ENST00000361773.3
transforming growth factor beta 1 induced transcript 1
chr14_-_21562671 2.11 ENST00000554923.1
zinc finger protein 219
chrX_-_17878827 2.11 ENST00000360011.1
retinoic acid induced 2
chr2_+_234580499 2.09 ENST00000354728.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr4_+_151503077 2.07 ENST00000317605.4
mab-21-like 2 (C. elegans)
chr11_+_27015628 2.06 ENST00000318627.2
fin bud initiation factor homolog (zebrafish)
chr15_+_74466744 2.05 ENST00000560862.1
ENST00000395118.1
immunoglobulin superfamily containing leucine-rich repeat
chr1_-_204135450 2.05 ENST00000272190.8
ENST00000367195.2
renin
chr12_-_6484715 2.04 ENST00000228916.2
sodium channel, non-voltage-gated 1 alpha subunit
chr4_-_41216492 2.02 ENST00000503503.1
ENST00000509446.1
ENST00000503264.1
ENST00000508707.1
ENST00000508593.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr3_+_148415571 2.01 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
angiotensin II receptor, type 1
chr8_-_13134246 2.01 ENST00000503161.2
deleted in liver cancer 1
chr15_+_43985084 1.96 ENST00000434505.1
ENST00000411750.1
creatine kinase, mitochondrial 1A
chr12_-_50616122 1.96 ENST00000552823.1
ENST00000552909.1
LIM domain and actin binding 1
chr1_+_209602609 1.96 ENST00000458250.1
MIR205 host gene (non-protein coding)
chr19_+_18496957 1.96 ENST00000252809.3
growth differentiation factor 15
chr4_+_41614909 1.96 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chrX_-_10544942 1.94 ENST00000380779.1
midline 1 (Opitz/BBB syndrome)
chr1_-_156675535 1.94 ENST00000368221.1
cellular retinoic acid binding protein 2
chr12_-_104443890 1.94 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
glycosyltransferase 8 domain containing 2
chr13_-_33780133 1.93 ENST00000399365.3
StAR-related lipid transfer (START) domain containing 13
chr4_-_73434498 1.86 ENST00000286657.4
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr12_+_54422142 1.86 ENST00000243108.4
homeobox C6
chr22_-_38380543 1.86 ENST00000396884.2
SRY (sex determining region Y)-box 10
chr3_+_151451707 1.86 ENST00000356517.3
arylacetamide deacetylase-like 2
chr6_+_151662815 1.86 ENST00000359755.5
A kinase (PRKA) anchor protein 12
chr1_-_156675368 1.85 ENST00000368222.3
cellular retinoic acid binding protein 2
chr4_-_41216473 1.84 ENST00000513140.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr10_-_50323543 1.84 ENST00000332853.4
ENST00000298454.3
V-set and transmembrane domain containing 4
chr11_-_9482010 1.84 ENST00000596206.1
LOC644656 protein; Uncharacterized protein
chr9_-_95186739 1.83 ENST00000375550.4
osteomodulin
chr5_+_38846101 1.82 ENST00000274276.3
oncostatin M receptor
chr16_+_86612112 1.82 ENST00000320241.3
forkhead box L1
chr2_+_27301435 1.81 ENST00000380320.4
elastin microfibril interfacer 1
chr14_+_63671577 1.81 ENST00000555125.1
ras homolog family member J
chr5_+_148960931 1.81 ENST00000333677.6
Rho guanine nucleotide exchange factor (GEF) 37
chr4_-_41750922 1.80 ENST00000226382.2
paired-like homeobox 2b
chr13_-_86373536 1.80 ENST00000400286.2
SLIT and NTRK-like family, member 6
chr12_-_7245018 1.79 ENST00000543835.1
ENST00000535233.2
complement component 1, r subcomponent
chr5_+_32788945 1.79 ENST00000326958.1
AC026703.1
chr12_+_12938541 1.78 ENST00000356591.4
apolipoprotein L domain containing 1
chr5_-_158526693 1.77 ENST00000380654.4
early B-cell factor 1
chr6_-_75912508 1.76 ENST00000416123.2
collagen, type XII, alpha 1
chr2_-_183387064 1.75 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
phosphodiesterase 1A, calmodulin-dependent
chr6_-_47010061 1.75 ENST00000371253.2
G protein-coupled receptor 110
chr9_+_124062071 1.74 ENST00000373818.4
gelsolin
chr6_-_10415470 1.73 ENST00000379604.2
ENST00000379613.3
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr7_-_156803329 1.70 ENST00000252971.6
motor neuron and pancreas homeobox 1
chr22_-_36236265 1.70 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RNA binding protein, fox-1 homolog (C. elegans) 2
chr20_+_55204351 1.70 ENST00000201031.2
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr11_-_76381029 1.69 ENST00000407242.2
ENST00000421973.1
leucine rich repeat containing 32
chr12_+_26348582 1.68 ENST00000535504.1
sarcospan
chr2_+_149974684 1.67 ENST00000450639.1
LY6/PLAUR domain containing 6B
chrX_+_105937068 1.67 ENST00000324342.3
ring finger protein 128, E3 ubiquitin protein ligase
chr12_+_52450298 1.67 ENST00000550582.2
nuclear receptor subfamily 4, group A, member 1
chr3_-_73673991 1.67 ENST00000308537.4
ENST00000263666.4
PDZ domain containing ring finger 3
chr5_+_38845960 1.66 ENST00000502536.1
oncostatin M receptor
chr6_-_112575912 1.66 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
laminin, alpha 4
chr4_-_71532207 1.66 ENST00000543780.1
ENST00000391614.3
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr20_-_57089934 1.65 ENST00000439429.1
ENST00000371149.3
adenomatosis polyposis coli down-regulated 1-like
chr1_-_32169920 1.65 ENST00000373672.3
ENST00000373668.3
collagen, type XVI, alpha 1
chr11_-_119293903 1.65 ENST00000580275.1
Thy-1 cell surface antigen
chr14_-_21562648 1.64 ENST00000555270.1
zinc finger protein 219
chr5_-_42812143 1.64 ENST00000514985.1
selenoprotein P, plasma, 1
chr17_+_48912744 1.64 ENST00000311378.4
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr4_+_55095264 1.63 ENST00000257290.5
platelet-derived growth factor receptor, alpha polypeptide
chr20_+_36149602 1.62 ENST00000062104.2
ENST00000346199.2
neuronatin
chr5_+_155753745 1.62 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr3_+_52828805 1.61 ENST00000416872.2
ENST00000449956.2
inter-alpha-trypsin inhibitor heavy chain 3
chr6_+_31916733 1.58 ENST00000483004.1
complement factor B
chr11_-_89223883 1.58 ENST00000528341.1
NADPH oxidase 4
chr12_+_54402790 1.58 ENST00000040584.4
homeobox C8
chr1_+_22138758 1.55 ENST00000344642.2
ENST00000543870.1
low density lipoprotein receptor class A domain containing 2
chr12_-_52585765 1.55 ENST00000313234.5
ENST00000394815.2
keratin 80
chr12_-_59314246 1.55 ENST00000320743.3
leucine-rich repeats and immunoglobulin-like domains 3
chr7_+_120629653 1.55 ENST00000450913.2
ENST00000340646.5
cadherin-like and PC-esterase domain containing 1
chr3_+_128720424 1.54 ENST00000480450.1
ENST00000436022.2
EF-hand and coiled-coil domain containing 1
chr5_+_140207536 1.54 ENST00000529310.1
ENST00000527624.1
protocadherin alpha 6
chr11_-_89224139 1.54 ENST00000413594.2
NADPH oxidase 4
chr1_-_171621815 1.53 ENST00000037502.6
myocilin, trabecular meshwork inducible glucocorticoid response
chr2_-_183387430 1.52 ENST00000410103.1
phosphodiesterase 1A, calmodulin-dependent
chr11_+_60467142 1.51 ENST00000529752.1
membrane-spanning 4-domains, subfamily A, member 8
chr6_-_112575758 1.51 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
laminin, alpha 4
chr5_+_140201183 1.49 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
protocadherin alpha 5
chr5_-_42811986 1.49 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr5_-_148758839 1.48 ENST00000261796.3
interleukin 17B
chr12_+_93130311 1.47 ENST00000344636.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr15_-_70994612 1.47 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr12_+_54447637 1.46 ENST00000609810.1
ENST00000430889.2
homeobox C4
Homeobox protein Hox-C4
chr1_-_32169761 1.46 ENST00000271069.6
collagen, type XVI, alpha 1
chr11_+_19799327 1.45 ENST00000540292.1
neuron navigator 2
chr9_+_137533615 1.44 ENST00000371817.3
collagen, type V, alpha 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC2_NFATC3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.9 GO:1902362 melanocyte apoptotic process(GO:1902362)
2.1 6.3 GO:1901207 mammary placode formation(GO:0060596) regulation of heart looping(GO:1901207)
1.9 5.7 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.8 5.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.5 23.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.4 5.5 GO:0009956 radial pattern formation(GO:0009956)
1.3 7.8 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
1.3 6.4 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.2 4.9 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
1.2 4.8 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
1.0 3.9 GO:0042663 regulation of pronephros size(GO:0035565) pronephric nephron tubule development(GO:0039020) regulation of endodermal cell fate specification(GO:0042663)
0.9 3.6 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.8 3.2 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.8 2.4 GO:0007412 axon target recognition(GO:0007412)
0.8 2.3 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.8 1.5 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.8 10.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.7 2.2 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.7 2.0 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.7 3.3 GO:0048749 compound eye development(GO:0048749)
0.7 1.3 GO:0042704 uterine wall breakdown(GO:0042704)
0.6 3.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.6 5.0 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.6 2.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.6 4.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.6 2.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.6 3.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.5 2.7 GO:0003409 optic cup structural organization(GO:0003409)
0.5 1.6 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.5 5.5 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.5 7.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.5 3.6 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.5 6.4 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.5 5.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.5 2.4 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.5 2.8 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.5 1.9 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.5 1.4 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.4 4.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.4 3.5 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.4 1.3 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) auditory receptor cell fate determination(GO:0042668) cell-cell signaling involved in cell fate commitment(GO:0045168) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.4 4.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.4 5.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.4 5.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.4 1.2 GO:0060279 positive regulation of ovulation(GO:0060279)
0.4 1.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.4 3.6 GO:0048539 bone marrow development(GO:0048539)
0.4 2.4 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.4 1.6 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.4 1.6 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.4 1.2 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.4 3.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.4 5.8 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.4 2.5 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.4 1.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 0.7 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.3 11.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 4.2 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.3 1.7 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.3 2.0 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 1.6 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3 2.6 GO:0035932 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.3 2.9 GO:0048664 neuron fate determination(GO:0048664)
0.3 2.9 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.3 4.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.3 1.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.3 2.4 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.3 1.8 GO:0021562 vestibulocochlear nerve development(GO:0021562) vestibular reflex(GO:0060005)
0.3 2.0 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.3 1.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.3 2.3 GO:0032439 endosome localization(GO:0032439)
0.3 4.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 1.4 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.3 5.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.3 0.3 GO:0014889 skeletal muscle atrophy(GO:0014732) muscle atrophy(GO:0014889) striated muscle atrophy(GO:0014891)
0.3 13.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.3 0.5 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.3 1.1 GO:0009386 translational attenuation(GO:0009386)
0.3 2.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 0.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 1.3 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.2 1.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.2 1.2 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.2 2.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.2 1.0 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.2 0.5 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.2 0.7 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.2 0.9 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 0.7 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 0.7 GO:0021569 rhombomere 3 development(GO:0021569)
0.2 2.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 2.0 GO:0070995 NADPH oxidation(GO:0070995)
0.2 1.6 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.2 2.0 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.2 0.9 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2 1.9 GO:0038089 positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
0.2 4.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 2.7 GO:0061042 vascular wound healing(GO:0061042)
0.2 1.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 1.2 GO:0071711 basement membrane organization(GO:0071711)
0.2 2.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 3.1 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.2 5.0 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.2 1.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 0.8 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.2 0.8 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.2 0.6 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.2 18.3 GO:0030574 collagen catabolic process(GO:0030574)
0.2 2.6 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2 0.7 GO:0014806 smooth muscle hyperplasia(GO:0014806)
0.2 1.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 0.7 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.2 0.9 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.2 2.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2 2.0 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 3.1 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 1.1 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.2 2.7 GO:0006600 creatine metabolic process(GO:0006600)
0.2 1.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 0.8 GO:0021553 olfactory nerve development(GO:0021553)
0.2 1.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 2.9 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 0.7 GO:0035993 deltoid tuberosity development(GO:0035993)
0.1 1.7 GO:0061469 response to corticotropin-releasing hormone(GO:0043435) regulation of type B pancreatic cell proliferation(GO:0061469) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 2.2 GO:2001212 regulation of vasculogenesis(GO:2001212)
0.1 0.4 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 1.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 2.1 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.4 GO:0045210 FasL biosynthetic process(GO:0045210)
0.1 0.8 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 1.6 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.9 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.6 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.5 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 1.0 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.6 GO:0001834 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 1.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.5 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 1.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 2.8 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.9 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 0.3 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.4 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.1 0.5 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 1.7 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.8 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.1 1.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 0.3 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.1 0.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.8 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 2.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.9 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.7 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 0.5 GO:0015862 uridine transport(GO:0015862)
0.1 0.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 2.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 3.1 GO:0033622 integrin activation(GO:0033622)
0.1 9.7 GO:0008542 visual learning(GO:0008542)
0.1 1.1 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 3.8 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.8 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 2.0 GO:0003334 keratinocyte development(GO:0003334)
0.1 4.4 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 16.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.3 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 2.2 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.8 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 1.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 1.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.5 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 0.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 1.3 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.1 1.0 GO:1901374 acetate ester transport(GO:1901374)
0.1 0.6 GO:0002159 desmosome assembly(GO:0002159)
0.1 1.1 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.7 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.9 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 0.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.2 GO:0051941 regulation of amino acid import(GO:0010958) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 1.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 1.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.1 GO:0038084 vascular endothelial growth factor signaling pathway(GO:0038084)
0.1 0.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 1.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.3 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 13.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.2 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.5 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 1.6 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 2.2 GO:0017144 drug metabolic process(GO:0017144)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.4 GO:1902731 negative regulation of chondrocyte proliferation(GO:1902731)
0.1 1.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 7.6 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.1 1.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 1.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.3 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.1 2.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.3 GO:0007621 courtship behavior(GO:0007619) negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050)
0.0 0.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.6 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.9 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 3.3 GO:0031529 ruffle organization(GO:0031529)
0.0 1.2 GO:0055001 muscle cell development(GO:0055001)
0.0 0.4 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 2.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.6 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 3.9 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.2 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.7 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 5.5 GO:0030449 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 0.1 GO:0048859 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) formation of anatomical boundary(GO:0048859) taste bud development(GO:0061193)
0.0 0.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.2 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.9 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.5 GO:0072189 ureter development(GO:0072189)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.9 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 1.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.9 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 3.3 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.7 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 2.1 GO:0050673 epithelial cell proliferation(GO:0050673)
0.0 1.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.7 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.2 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 1.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:2000018 regulation of male gonad development(GO:2000018) positive regulation of male gonad development(GO:2000020)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0030222 eosinophil differentiation(GO:0030222) regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.4 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 2.7 GO:0048678 response to axon injury(GO:0048678)
0.0 2.3 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.9 GO:0015695 organic cation transport(GO:0015695)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.9 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 1.2 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.0 1.0 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.0 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 1.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.9 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 1.4 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.4 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.7 GO:0008038 neuron recognition(GO:0008038)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 2.8 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.6 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.5 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.8 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.2 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 1.5 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.3 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 2.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.8 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.2 GO:0043586 tongue development(GO:0043586)
0.0 0.1 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 0.3 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 1.4 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 2.4 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
2.1 31.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.8 5.5 GO:0005588 collagen type V trimer(GO:0005588)
1.5 5.9 GO:0045160 myosin I complex(GO:0045160)
1.2 3.5 GO:0005900 oncostatin-M receptor complex(GO:0005900)
1.1 5.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
1.0 10.7 GO:0071953 elastic fiber(GO:0071953)
0.6 10.9 GO:0071438 invadopodium membrane(GO:0071438)
0.6 1.8 GO:0005595 collagen type XII trimer(GO:0005595)
0.6 18.1 GO:0005614 interstitial matrix(GO:0005614)
0.5 2.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.5 10.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.4 1.3 GO:1990032 parallel fiber(GO:1990032)
0.4 1.2 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 3.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 3.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.3 3.2 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.3 0.9 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.3 2.0 GO:0036021 endolysosome lumen(GO:0036021)
0.3 4.3 GO:0030478 actin cap(GO:0030478)
0.3 6.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 1.1 GO:0032279 asymmetric synapse(GO:0032279)
0.2 2.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 1.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.2 1.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 3.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 5.0 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.2 6.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.7 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 2.0 GO:0097433 dense body(GO:0097433)
0.1 0.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 2.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 2.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.1 GO:0001739 sex chromatin(GO:0001739)
0.1 8.4 GO:0016235 aggresome(GO:0016235)
0.1 4.6 GO:0005605 basal lamina(GO:0005605)
0.1 1.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.9 GO:0044305 calyx of Held(GO:0044305)
0.1 2.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.5 GO:0045179 apical cortex(GO:0045179)
0.1 1.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.4 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 1.6 GO:0008091 spectrin(GO:0008091)
0.1 1.6 GO:0005884 actin filament(GO:0005884)
0.1 1.2 GO:0097512 cardiac myofibril(GO:0097512)
0.1 5.0 GO:0030286 dynein complex(GO:0030286)
0.1 2.0 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.1 2.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 29.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 0.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 11.5 GO:0005923 bicellular tight junction(GO:0005923)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 2.6 GO:0051233 spindle midzone(GO:0051233)
0.1 1.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 5.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.9 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 6.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.6 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)
0.0 1.9 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.7 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 2.1 GO:0030426 growth cone(GO:0030426)
0.0 0.5 GO:1990752 microtubule end(GO:1990752)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 2.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 2.5 GO:0045095 keratin filament(GO:0045095)
0.0 4.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.8 GO:0010369 chromocenter(GO:0010369)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)
0.0 4.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 11.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.5 GO:0045177 apical part of cell(GO:0045177)
0.0 0.5 GO:0005771 multivesicular body(GO:0005771)
0.0 0.6 GO:0005901 caveola(GO:0005901)
0.0 2.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 10.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.9 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 2.4 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.6 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0001596 angiotensin type I receptor activity(GO:0001596)
1.0 4.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.8 5.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.8 2.4 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.7 5.9 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.7 5.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.6 1.8 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.6 4.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.6 2.4 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.6 3.5 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.6 2.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.4 2.7 GO:0097001 ceramide binding(GO:0097001)
0.4 1.3 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.4 4.8 GO:0034235 GPI anchor binding(GO:0034235)
0.4 3.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.4 1.6 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.4 3.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.4 2.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 3.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4 1.9 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.4 17.6 GO:0001972 retinoic acid binding(GO:0001972)
0.3 1.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor beta-receptor activity(GO:0005019)
0.3 1.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 1.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.3 10.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 2.9 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.3 5.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.3 2.4 GO:0098639 protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 1.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 41.6 GO:0005518 collagen binding(GO:0005518)
0.3 1.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.3 4.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.3 9.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 2.7 GO:0004111 creatine kinase activity(GO:0004111)
0.3 6.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 1.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 1.0 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.2 0.7 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 1.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 2.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 2.8 GO:0004969 histamine receptor activity(GO:0004969)
0.2 0.9 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.2 6.9 GO:0001968 fibronectin binding(GO:0001968)
0.2 2.1 GO:0048495 Roundabout binding(GO:0048495)
0.2 3.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 4.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 1.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.2 0.6 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.2 0.9 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 4.0 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 1.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 0.7 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 1.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 1.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 0.7 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.2 5.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 2.3 GO:0070700 BMP receptor binding(GO:0070700)
0.2 1.4 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 1.0 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 3.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 2.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 1.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.4 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 1.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 5.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 4.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.9 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 1.6 GO:0042731 PH domain binding(GO:0042731)
0.1 4.2 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.5 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 2.3 GO:0000146 microfilament motor activity(GO:0000146)
0.1 1.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 2.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.7 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.5 GO:0035939 microsatellite binding(GO:0035939)
0.1 1.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 2.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.9 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 2.0 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 10.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 4.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 3.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 3.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.8 GO:0005534 galactose binding(GO:0005534)
0.1 0.3 GO:0031432 titin binding(GO:0031432)
0.1 0.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.9 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 0.7 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 1.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 1.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.5 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 11.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.8 GO:0005109 frizzled binding(GO:0005109)
0.1 4.8 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.5 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 2.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.6 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 3.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 8.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 12.1 GO:0005178 integrin binding(GO:0005178)
0.1 1.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 4.1 GO:0050699 WW domain binding(GO:0050699)
0.1 0.3 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 1.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.4 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.6 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.9 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.7 GO:0001848 complement binding(GO:0001848)
0.0 1.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 3.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 1.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 5.8 GO:0005179 hormone activity(GO:0005179)
0.0 6.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 3.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 1.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 3.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.4 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 34.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 13.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.0 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 1.3 GO:0005549 odorant binding(GO:0005549)
0.0 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 1.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.0 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0043394 proteoglycan binding(GO:0043394) heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.2 GO:0019838 growth factor binding(GO:0019838)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 1.9 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 25.9 NABA COLLAGENS Genes encoding collagen proteins
0.3 23.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 1.1 PID CD40 PATHWAY CD40/CD40L signaling
0.2 13.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 0.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 2.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 5.5 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 37.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.3 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 6.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.5 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 1.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 6.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 6.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 7.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 19.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.9 PID IGF1 PATHWAY IGF1 pathway
0.0 3.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 3.0 PID AURORA B PATHWAY Aurora B signaling
0.0 3.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 2.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 4.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 11.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.7 21.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 8.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 28.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 10.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 7.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 3.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 12.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 3.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 3.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 6.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.0 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 1.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 1.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 4.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 3.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.7 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 8.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 4.9 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.9 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 2.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 2.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.9 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.3 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 1.5 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 1.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.9 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.6 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.2 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 3.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME METABOLISM OF RNA Genes involved in Metabolism of RNA
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 3.1 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism