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Illumina Body Map 2, young vs old

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Results for NKX2-2

Z-value: 0.39

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Transcription factors associated with NKX2-2

Gene Symbol Gene ID Gene Info
NKX2-2
ENSG00000125820.5 NK2 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-2hg19_v2_chr20_-_21494654_21494678-0.336.5e-02Click!

Activity profile of NKX2-2 motif

Sorted Z-values of NKX2-2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_54689532 2.82 ENST00000540264.2
ENST00000312156.4
NFE2
nuclear factor, erythroid 2
chr7_+_37723450 2.61 ENST00000447769.1
GPR141
G protein-coupled receptor 141
chr7_+_37723336 2.52 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr9_-_85882145 1.86 ENST00000328788.1
FRMD3
FERM domain containing 3
chr3_-_150920979 1.70 ENST00000309180.5
ENST00000480322.1
GPR171
G protein-coupled receptor 171
chr8_-_133772870 1.54 ENST00000522334.1
ENST00000519016.1
TMEM71
transmembrane protein 71
chr3_-_33686925 1.54 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr5_+_82767583 1.43 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN
versican
chr4_-_40477766 1.38 ENST00000507180.1
RBM47
RNA binding motif protein 47
chr8_-_133772794 1.37 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
TMEM71
transmembrane protein 71
chr12_+_8666126 1.37 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr10_-_36813162 1.33 ENST00000440465.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr3_+_151591422 1.26 ENST00000362032.5
SUCNR1
succinate receptor 1
chr1_-_153363452 1.26 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr2_-_214013353 1.25 ENST00000451136.2
ENST00000421754.2
ENST00000374327.4
ENST00000413091.3
IKZF2
IKAROS family zinc finger 2 (Helios)
chr4_+_160203650 1.24 ENST00000514565.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr10_-_36812323 1.24 ENST00000543053.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chrM_+_12331 1.21 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr5_+_82767487 1.19 ENST00000343200.5
ENST00000342785.4
VCAN
versican
chr10_-_104913367 1.17 ENST00000423468.2
NT5C2
5'-nucleotidase, cytosolic II
chr6_-_116833500 1.17 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr7_+_16700806 1.17 ENST00000446596.1
ENST00000438834.1
BZW2
basic leucine zipper and W2 domains 2
chr11_+_65266507 1.13 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr7_+_80253387 1.10 ENST00000438020.1
CD36
CD36 molecule (thrombospondin receptor)
chr5_+_154181816 1.09 ENST00000518677.1
LARP1
La ribonucleoprotein domain family, member 1
chr18_+_32558380 1.08 ENST00000588349.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr3_+_69811858 1.07 ENST00000433517.1
MITF
microphthalmia-associated transcription factor
chr14_+_39734482 1.07 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
CTAGE5
CTAGE family, member 5
chrX_-_15333775 1.06 ENST00000480796.1
ASB11
ankyrin repeat and SOCS box containing 11
chr2_+_102953608 1.03 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr7_+_80254279 1.02 ENST00000436384.1
CD36
CD36 molecule (thrombospondin receptor)
chr4_+_95376396 1.02 ENST00000508216.1
ENST00000514743.1
PDLIM5
PDZ and LIM domain 5
chr21_+_30672433 1.02 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr15_-_60683326 1.01 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
ANXA2
annexin A2
chr12_+_69202795 0.99 ENST00000539479.1
ENST00000393415.3
ENST00000523991.1
ENST00000543323.1
ENST00000393416.2
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr1_+_84629976 0.98 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_154150651 0.97 ENST00000302206.5
TPM3
tropomyosin 3
chr5_+_75904918 0.96 ENST00000514001.1
ENST00000396234.3
ENST00000509074.1
IQGAP2
IQ motif containing GTPase activating protein 2
chr12_+_69202975 0.95 ENST00000544561.1
ENST00000393410.1
ENST00000299252.4
ENST00000360430.2
ENST00000517852.1
ENST00000545204.1
ENST00000393413.3
ENST00000350057.5
ENST00000348801.2
ENST00000478070.1
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr2_-_145188137 0.95 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr5_+_148206156 0.94 ENST00000305988.4
ADRB2
adrenoceptor beta 2, surface
chr22_-_50523807 0.93 ENST00000442311.1
ENST00000538737.1
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr17_-_29641084 0.93 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr22_-_43567750 0.91 ENST00000494035.1
TTLL12
tubulin tyrosine ligase-like family, member 12
chr7_-_24957699 0.91 ENST00000441059.1
ENST00000415162.1
OSBPL3
oxysterol binding protein-like 3
chr14_-_89878369 0.91 ENST00000553840.1
ENST00000556916.1
FOXN3
forkhead box N3
chr3_+_63953415 0.90 ENST00000484332.1
ATXN7
ataxin 7
chr16_+_53241854 0.90 ENST00000565803.1
CHD9
chromodomain helicase DNA binding protein 9
chr3_-_33686743 0.90 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr13_-_45048386 0.89 ENST00000472477.1
TSC22D1
TSC22 domain family, member 1
chr7_-_142120321 0.87 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr3_+_152017181 0.87 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1
muscleblind-like splicing regulator 1
chr9_-_139361503 0.86 ENST00000453963.1
SEC16A
SEC16 homolog A (S. cerevisiae)
chr9_+_129097520 0.86 ENST00000436593.3
MVB12B
multivesicular body subunit 12B
chr10_-_61513201 0.85 ENST00000414264.1
ENST00000594536.1
LINC00948
long intergenic non-protein coding RNA 948
chr2_-_214015111 0.85 ENST00000433134.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr19_-_14889349 0.84 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr1_+_84630352 0.84 ENST00000450730.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr6_+_140175987 0.84 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
RP5-899B16.1
chr3_-_152058779 0.84 ENST00000408960.3
TMEM14E
transmembrane protein 14E
chr7_+_133615169 0.83 ENST00000541309.1
EXOC4
exocyst complex component 4
chr3_-_150966902 0.83 ENST00000424796.2
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr8_-_134072593 0.83 ENST00000427060.2
SLA
Src-like-adaptor
chr22_-_50523688 0.82 ENST00000450140.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr1_-_54405773 0.82 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chrX_-_70474910 0.82 ENST00000373988.1
ENST00000373998.1
ZMYM3
zinc finger, MYM-type 3
chrX_-_19817869 0.81 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chrX_+_123095890 0.81 ENST00000435215.1
STAG2
stromal antigen 2
chr20_-_60573188 0.81 ENST00000474089.1
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr21_+_17214724 0.81 ENST00000449491.1
USP25
ubiquitin specific peptidase 25
chr17_+_66511224 0.81 ENST00000588178.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr1_+_84630053 0.81 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr14_+_39703084 0.80 ENST00000553728.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr1_-_216978709 0.80 ENST00000360012.3
ESRRG
estrogen-related receptor gamma
chr1_+_104293028 0.80 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr3_-_69249863 0.80 ENST00000478263.1
ENST00000462512.1
FRMD4B
FERM domain containing 4B
chr5_+_75904950 0.79 ENST00000502745.1
IQGAP2
IQ motif containing GTPase activating protein 2
chr3_+_142838091 0.78 ENST00000309575.3
CHST2
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr3_+_41241596 0.78 ENST00000450969.1
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr18_-_67615088 0.77 ENST00000582621.1
CD226
CD226 molecule
chr20_+_30102231 0.77 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
HM13
histocompatibility (minor) 13
chr14_+_61449076 0.77 ENST00000526105.1
SLC38A6
solute carrier family 38, member 6
chr11_+_64949899 0.77 ENST00000531068.1
ENST00000527699.1
ENST00000533909.1
ENST00000527323.1
CAPN1
calpain 1, (mu/I) large subunit
chr19_-_44174305 0.77 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr1_-_223308098 0.76 ENST00000342210.6
TLR5
toll-like receptor 5
chr10_-_121296045 0.76 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr2_+_219110149 0.76 ENST00000456575.1
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr3_-_121379739 0.76 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr2_+_201994569 0.75 ENST00000457277.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr19_+_7445850 0.75 ENST00000593531.1
CTD-2207O23.3
Rho guanine nucleotide exchange factor 18
chr9_+_131447342 0.75 ENST00000409104.3
SET
SET nuclear oncogene
chrX_+_105445717 0.74 ENST00000372552.1
MUM1L1
melanoma associated antigen (mutated) 1-like 1
chr19_-_44174330 0.74 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr22_-_50523760 0.74 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chrX_-_154033661 0.74 ENST00000393531.1
MPP1
membrane protein, palmitoylated 1, 55kDa
chr1_-_150944411 0.73 ENST00000368949.4
CERS2
ceramide synthase 2
chrX_-_70474499 0.73 ENST00000353904.2
ZMYM3
zinc finger, MYM-type 3
chr3_+_98482175 0.73 ENST00000485391.1
ENST00000492254.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr2_+_74229812 0.72 ENST00000305799.7
TET3
tet methylcytosine dioxygenase 3
chr2_-_214014959 0.72 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
IKZF2
IKAROS family zinc finger 2 (Helios)
chr2_-_38056538 0.72 ENST00000413792.1
LINC00211
long intergenic non-protein coding RNA 211
chrX_+_123095860 0.71 ENST00000428941.1
STAG2
stromal antigen 2
chr10_-_94003003 0.71 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr12_-_58240470 0.71 ENST00000548823.1
ENST00000398073.2
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr4_+_89299885 0.71 ENST00000380265.5
ENST00000273960.3
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr3_+_190281229 0.70 ENST00000453359.1
IL1RAP
interleukin 1 receptor accessory protein
chr5_+_179135246 0.70 ENST00000508787.1
CANX
calnexin
chr12_-_49582978 0.70 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr5_-_78281775 0.69 ENST00000396151.3
ENST00000565165.1
ARSB
arylsulfatase B
chr14_-_31856397 0.69 ENST00000538864.2
ENST00000550366.1
HEATR5A
HEAT repeat containing 5A
chr7_+_115862858 0.68 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr5_-_88180342 0.68 ENST00000502983.1
MEF2C
myocyte enhancer factor 2C
chr9_-_20622478 0.68 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chrX_+_123095546 0.68 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr6_+_158733692 0.67 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr11_-_13517565 0.67 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr1_-_207095324 0.67 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr12_-_70093111 0.67 ENST00000548658.1
ENST00000476098.1
ENST00000331471.4
ENST00000393365.1
BEST3
bestrophin 3
chr13_-_41240717 0.67 ENST00000379561.5
FOXO1
forkhead box O1
chr5_-_58652788 0.67 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_-_42631529 0.66 ENST00000548917.1
YAF2
YY1 associated factor 2
chr12_+_9066472 0.66 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr1_-_155880672 0.65 ENST00000609492.1
ENST00000368322.3
RIT1
Ras-like without CAAX 1
chr11_-_11374904 0.65 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr14_+_23654525 0.65 ENST00000399910.1
ENST00000492621.1
C14orf164
chromosome 14 open reading frame 164
chr2_+_224822121 0.65 ENST00000258383.3
MRPL44
mitochondrial ribosomal protein L44
chr14_+_22520762 0.64 ENST00000390449.3
TRAV21
T cell receptor alpha variable 21
chr2_-_145275828 0.64 ENST00000392861.2
ENST00000409211.1
ZEB2
zinc finger E-box binding homeobox 2
chr5_+_135394840 0.64 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr1_+_117963209 0.64 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr2_+_201994208 0.64 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr9_+_137218362 0.63 ENST00000481739.1
RXRA
retinoid X receptor, alpha
chr1_-_31538517 0.63 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
PUM1
pumilio RNA-binding family member 1
chrX_-_15333736 0.63 ENST00000380470.3
ASB11
ankyrin repeat and SOCS box containing 11
chr17_-_29641104 0.63 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr14_-_100841794 0.62 ENST00000556295.1
ENST00000554820.1
WARS
tryptophanyl-tRNA synthetase
chr7_+_2393714 0.61 ENST00000431643.1
EIF3B
eukaryotic translation initiation factor 3, subunit B
chr1_+_84630367 0.61 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr10_+_98741041 0.61 ENST00000286067.2
C10orf12
chromosome 10 open reading frame 12
chr22_-_42086477 0.61 ENST00000402458.1
NHP2L1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr17_+_66521936 0.61 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr6_+_10633993 0.60 ENST00000417671.1
GCNT6
glucosaminyl (N-acetyl) transferase 6
chr9_+_103340354 0.60 ENST00000307584.5
MURC
muscle-related coiled-coil protein
chr1_-_207095212 0.60 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr12_+_32552451 0.60 ENST00000534526.2
FGD4
FYVE, RhoGEF and PH domain containing 4
chr11_+_93479588 0.60 ENST00000526335.1
C11orf54
chromosome 11 open reading frame 54
chr13_+_111855399 0.60 ENST00000426768.2
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr2_-_27558270 0.59 ENST00000454704.1
GTF3C2
general transcription factor IIIC, polypeptide 2, beta 110kDa
chr12_-_10978957 0.59 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr6_+_159084188 0.59 ENST00000367081.3
SYTL3
synaptotagmin-like 3
chrX_-_23761317 0.59 ENST00000492081.1
ENST00000379303.5
ENST00000336430.7
ACOT9
acyl-CoA thioesterase 9
chr3_-_113897899 0.59 ENST00000383673.2
ENST00000295881.7
DRD3
dopamine receptor D3
chr6_-_150067632 0.57 ENST00000460354.2
ENST00000367404.4
ENST00000543637.1
NUP43
nucleoporin 43kDa
chr1_+_161691353 0.57 ENST00000367948.2
FCRLB
Fc receptor-like B
chr7_-_38339890 0.57 ENST00000390341.2
TRGV10
T cell receptor gamma variable 10 (non-functional)
chr2_+_183582774 0.56 ENST00000537515.1
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr5_+_118812294 0.55 ENST00000509514.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr8_-_101962777 0.55 ENST00000395951.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr10_-_27529486 0.55 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr3_+_98482159 0.55 ENST00000468553.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr6_+_20534672 0.55 ENST00000274695.4
ENST00000378624.4
CDKAL1
CDK5 regulatory subunit associated protein 1-like 1
chr13_+_113863858 0.54 ENST00000375440.4
CUL4A
cullin 4A
chr3_-_196911002 0.54 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr9_+_116263639 0.54 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr5_-_58335281 0.54 ENST00000358923.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr13_+_111855414 0.54 ENST00000375737.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr10_+_63808970 0.53 ENST00000309334.5
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr9_+_129097479 0.53 ENST00000402437.2
MVB12B
multivesicular body subunit 12B
chr1_+_54359854 0.53 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
DIO1
deiodinase, iodothyronine, type I
chr17_+_7591747 0.53 ENST00000534050.1
WRAP53
WD repeat containing, antisense to TP53
chr20_-_36152914 0.53 ENST00000397131.1
BLCAP
bladder cancer associated protein
chr13_+_25875785 0.53 ENST00000381747.3
NUPL1
nucleoporin like 1
chr9_-_86593238 0.53 ENST00000351839.3
HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr15_+_79165296 0.53 ENST00000558746.1
ENST00000558830.1
ENST00000559345.1
MORF4L1
mortality factor 4 like 1
chr14_-_100841670 0.52 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
WARS
tryptophanyl-tRNA synthetase
chr7_-_944631 0.52 ENST00000453175.2
ADAP1
ArfGAP with dual PH domains 1
chr15_+_81391740 0.52 ENST00000561216.1
C15orf26
chromosome 15 open reading frame 26
chr4_+_87928140 0.52 ENST00000307808.6
AFF1
AF4/FMR2 family, member 1
chr18_-_43684230 0.52 ENST00000592989.1
ENST00000589869.1
ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr10_+_81462983 0.52 ENST00000448135.1
ENST00000429828.1
ENST00000372321.1
NUTM2B
NUT family member 2B
chr18_-_60986613 0.51 ENST00000444484.1
BCL2
B-cell CLL/lymphoma 2
chr15_-_56209306 0.51 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr8_-_124279627 0.51 ENST00000357082.4
ZHX1-C8ORF76
ZHX1-C8ORF76 readthrough
chr15_-_60690163 0.51 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2
annexin A2
chr14_-_100841930 0.51 ENST00000555031.1
ENST00000553395.1
ENST00000553545.1
ENST00000344102.5
ENST00000556338.1
ENST00000392882.2
ENST00000553934.1
WARS
tryptophanyl-tRNA synthetase
chr15_+_79165372 0.50 ENST00000558502.1
MORF4L1
mortality factor 4 like 1
chr13_-_99630233 0.50 ENST00000376460.1
ENST00000442173.1
DOCK9
dedicator of cytokinesis 9
chr5_+_118812237 0.50 ENST00000513628.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr17_+_7591639 0.50 ENST00000396463.2
WRAP53
WD repeat containing, antisense to TP53
chr1_-_9953295 0.50 ENST00000377258.1
CTNNBIP1
catenin, beta interacting protein 1
chr6_+_148593425 0.50 ENST00000367469.1
SASH1
SAM and SH3 domain containing 1
chr11_+_94277017 0.50 ENST00000358752.2
FUT4
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr14_+_22964877 0.50 ENST00000390494.1
TRAJ43
T cell receptor alpha joining 43
chr5_-_58571935 0.50 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr22_+_42086547 0.50 ENST00000402966.1
C22orf46
chromosome 22 open reading frame 46
chr12_-_10875831 0.49 ENST00000279550.7
ENST00000228251.4
YBX3
Y box binding protein 3
chr20_+_30697510 0.49 ENST00000217315.5
TM9SF4
transmembrane 9 superfamily protein member 4
chr18_-_60985914 0.49 ENST00000589955.1
BCL2
B-cell CLL/lymphoma 2
chr12_+_14572070 0.49 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr2_+_162087577 0.49 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.4 1.5 GO:0044145 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.3 1.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.3 1.0 GO:0061580 colon epithelial cell migration(GO:0061580)
0.3 3.2 GO:0097338 response to clozapine(GO:0097338)
0.3 0.9 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.3 1.7 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 2.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.3 0.8 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.3 0.5 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.3 0.8 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.3 1.0 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.2 1.7 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 0.7 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.2 0.7 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.2 0.7 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 0.7 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 0.6 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.2 1.0 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 1.4 GO:0019075 virus maturation(GO:0019075)
0.2 0.8 GO:1904499 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.2 2.1 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 1.5 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 0.7 GO:1905044 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.2 1.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.2 0.5 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 1.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.2 1.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.2 1.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 2.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.6 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 2.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 3.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.8 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.8 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.1 1.4 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 1.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.5 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 0.5 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.7 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 1.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.7 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.4 GO:0042369 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369)
0.1 0.6 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.6 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.3 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 2.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 2.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.3 GO:0050904 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.1 0.6 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 1.5 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.3 GO:0009405 pathogenesis(GO:0009405)
0.1 0.4 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.6 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 1.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.3 GO:0061569 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.4 GO:2000845 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.2 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.2 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.5 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.1 0.4 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.7 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.3 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.6 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 1.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 1.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.5 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.9 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.3 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 0.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 1.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.5 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.3 GO:0019249 lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.6 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.3 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.1 0.5 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 0.6 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.8 GO:0060056 mammary gland involution(GO:0060056)
0.0 1.3 GO:0002544 leukocyte migration involved in inflammatory response(GO:0002523) chronic inflammatory response(GO:0002544)
0.0 0.8 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:1990637 response to prolactin(GO:1990637)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.8 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.8 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.4 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 1.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.5 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.5 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.3 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.4 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.5 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.8 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.8 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:2000078 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 1.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.3 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 1.6 GO:2000142 regulation of DNA-templated transcription, initiation(GO:2000142)
0.0 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 1.3 GO:0097503 cellular response to interleukin-6(GO:0071354) sialylation(GO:0097503)
0.0 0.4 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.7 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.6 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 0.1 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.2 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.5 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 1.0 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.0 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.1 GO:1901529 transepithelial water transport(GO:0035377) positive regulation of anion channel activity(GO:1901529) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) positive regulation of inorganic anion transmembrane transport(GO:1903797) positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.3 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 1.4 GO:0002292 T cell differentiation involved in immune response(GO:0002292)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 1.2 GO:0016569 covalent chromatin modification(GO:0016569)
0.0 0.2 GO:0090050 peptidyl-lysine deacetylation(GO:0034983) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.7 GO:0048255 mRNA stabilization(GO:0048255)
0.0 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.9 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.5 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.9 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.5 GO:0016577 histone demethylation(GO:0016577)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.3 0.8 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 0.7 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 0.8 GO:0071020 post-spliceosomal complex(GO:0071020)
0.2 4.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.8 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.2 2.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.7 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 1.5 GO:0000322 storage vacuole(GO:0000322)
0.1 1.3 GO:0001940 male pronucleus(GO:0001940)
0.1 0.8 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.1 1.5 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.4 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.4 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.8 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.1 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.4 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 0.7 GO:0042382 paraspeckles(GO:0042382)
0.1 0.5 GO:0002177 manchette(GO:0002177)
0.1 1.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 1.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.9 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.5 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.9 GO:0032433 filopodium tip(GO:0032433)
0.0 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0043219 lateral loop(GO:0043219)
0.0 0.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.8 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 2.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 1.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.9 GO:0016605 PML body(GO:0016605)
0.0 2.3 GO:0005901 caveola(GO:0005901)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.6 GO:0031105 septin complex(GO:0031105)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 1.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 4.9 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.0 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 1.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.4 1.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.3 1.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.3 0.9 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.3 1.7 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.3 1.3 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2 1.0 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2 0.7 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.2 0.9 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 1.5 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 0.8 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.2 2.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.7 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 1.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 1.1 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.2 0.7 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.2 0.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 0.8 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 1.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 3.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.8 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.6 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.4 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 1.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 2.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.8 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.3 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 2.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.0 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 2.1 GO:0008494 translation activator activity(GO:0008494)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.5 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.3 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 1.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 2.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 4.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.5 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 1.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.6 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.8 GO:0017162 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 8.0 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 1.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 1.1 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 1.0 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.8 GO:0043495 protein anchor(GO:0043495)
0.0 1.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) TFIIB-class transcription factor binding(GO:0001093)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.9 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 1.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 2.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 3.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.5 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 4.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 2.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.7 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.7 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 2.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.0 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 3.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4