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Illumina Body Map 2, young vs old
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Results for NKX2-8
Z-value: 0.35
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Transcription factors associated with NKX2-8
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
NKX2-8
|
ENSG00000136327.6 | NK2 homeobox 8 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NKX2-8 | hg19_v2_chr14_-_37051798_37051831 | 0.32 | 7.1e-02 | Click! |
Activity profile of NKX2-8 motif
Sorted Z-values of NKX2-8 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_-_106573756 | 4.84 |
ENST00000390601.2
|
IGHV3-11
|
immunoglobulin heavy variable 3-11 (gene/pseudogene) |
| chr14_-_107049312 | 4.79 |
ENST00000390627.2
|
IGHV3-53
|
immunoglobulin heavy variable 3-53 |
| chr14_-_106552755 | 4.45 |
ENST00000390600.2
|
IGHV3-9
|
immunoglobulin heavy variable 3-9 |
| chr14_-_107199464 | 4.34 |
ENST00000433072.2
|
IGHV3-72
|
immunoglobulin heavy variable 3-72 |
| chr14_-_106518922 | 4.27 |
ENST00000390598.2
|
IGHV3-7
|
immunoglobulin heavy variable 3-7 |
| chr14_-_106692191 | 4.22 |
ENST00000390607.2
|
IGHV3-21
|
immunoglobulin heavy variable 3-21 |
| chr14_-_106586656 | 4.20 |
ENST00000390602.2
|
IGHV3-13
|
immunoglobulin heavy variable 3-13 |
| chr14_-_107131560 | 4.01 |
ENST00000390632.2
|
IGHV3-66
|
immunoglobulin heavy variable 3-66 |
| chr14_-_106994333 | 3.73 |
ENST00000390624.2
|
IGHV3-48
|
immunoglobulin heavy variable 3-48 |
| chr14_-_106622419 | 3.47 |
ENST00000390604.2
|
IGHV3-16
|
immunoglobulin heavy variable 3-16 (non-functional) |
| chr16_+_32063311 | 3.17 |
ENST00000426099.1
|
AC142381.1
|
AC142381.1 |
| chr14_-_106791536 | 3.08 |
ENST00000390613.2
|
IGHV3-30
|
immunoglobulin heavy variable 3-30 |
| chr14_-_107219365 | 3.03 |
ENST00000424969.2
|
IGHV3-74
|
immunoglobulin heavy variable 3-74 |
| chr14_-_106845789 | 2.85 |
ENST00000390617.2
|
IGHV3-35
|
immunoglobulin heavy variable 3-35 (non-functional) |
| chr17_+_37784749 | 2.82 |
ENST00000394265.1
ENST00000394267.2 |
PPP1R1B
|
protein phosphatase 1, regulatory (inhibitor) subunit 1B |
| chr14_-_106963409 | 2.82 |
ENST00000390621.2
|
IGHV1-45
|
immunoglobulin heavy variable 1-45 |
| chr14_+_22356029 | 2.70 |
ENST00000390437.2
|
TRAV12-2
|
T cell receptor alpha variable 12-2 |
| chr14_+_22362613 | 2.52 |
ENST00000390438.2
|
TRAV8-4
|
T cell receptor alpha variable 8-4 |
| chr16_-_33647696 | 2.42 |
ENST00000558425.1
ENST00000569103.2 |
RP11-812E19.9
|
Uncharacterized protein |
| chr15_-_20170354 | 2.41 |
ENST00000338912.5
|
IGHV1OR15-9
|
immunoglobulin heavy variable 1/OR15-9 (non-functional) |
| chr3_+_111717511 | 2.20 |
ENST00000478951.1
ENST00000393917.2 |
TAGLN3
|
transgelin 3 |
| chr16_+_89696692 | 2.20 |
ENST00000261615.4
|
DPEP1
|
dipeptidase 1 (renal) |
| chr5_+_156607829 | 2.17 |
ENST00000422843.3
|
ITK
|
IL2-inducible T-cell kinase |
| chr16_+_33020496 | 2.16 |
ENST00000565407.2
|
IGHV3OR16-8
|
immunoglobulin heavy variable 3/OR16-8 (non-functional) |
| chr22_-_30925150 | 2.06 |
ENST00000437871.1
|
SEC14L6
|
SEC14-like 6 (S. cerevisiae) |
| chr6_-_32731243 | 2.05 |
ENST00000427449.1
ENST00000411527.1 |
HLA-DQB2
|
major histocompatibility complex, class II, DQ beta 2 |
| chr3_+_111717600 | 2.05 |
ENST00000273368.4
|
TAGLN3
|
transgelin 3 |
| chr16_+_33006369 | 2.03 |
ENST00000425181.3
|
IGHV3OR16-10
|
immunoglobulin heavy variable 3/OR16-10 (non-functional) |
| chr2_-_36779411 | 1.98 |
ENST00000406220.1
|
AC007401.2
|
Uncharacterized protein |
| chr5_-_176056974 | 1.97 |
ENST00000510387.1
ENST00000506696.1 |
SNCB
|
synuclein, beta |
| chr19_-_17622269 | 1.96 |
ENST00000595116.1
|
CTD-3131K8.2
|
CTD-3131K8.2 |
| chr6_-_32731299 | 1.96 |
ENST00000435145.2
ENST00000437316.2 |
HLA-DQB2
|
major histocompatibility complex, class II, DQ beta 2 |
| chr3_+_137728842 | 1.91 |
ENST00000183605.5
|
CLDN18
|
claudin 18 |
| chr16_+_32077386 | 1.88 |
ENST00000354689.6
|
IGHV3OR16-9
|
immunoglobulin heavy variable 3/OR16-9 (non-functional) |
| chr22_+_29834572 | 1.83 |
ENST00000354373.2
|
RFPL1
|
ret finger protein-like 1 |
| chr3_-_116163830 | 1.82 |
ENST00000333617.4
|
LSAMP
|
limbic system-associated membrane protein |
| chr16_+_33629600 | 1.78 |
ENST00000562905.2
|
IGHV3OR16-13
|
immunoglobulin heavy variable 3/OR16-13 (non-functional) |
| chr2_+_204801471 | 1.76 |
ENST00000316386.6
ENST00000435193.1 |
ICOS
|
inducible T-cell co-stimulator |
| chr5_+_92919043 | 1.72 |
ENST00000327111.3
|
NR2F1
|
nuclear receptor subfamily 2, group F, member 1 |
| chr5_+_35852797 | 1.69 |
ENST00000508941.1
|
IL7R
|
interleukin 7 receptor |
| chr5_+_3596168 | 1.68 |
ENST00000302006.3
|
IRX1
|
iroquois homeobox 1 |
| chr14_-_24732403 | 1.68 |
ENST00000206765.6
|
TGM1
|
transglutaminase 1 |
| chr13_-_46964177 | 1.64 |
ENST00000389908.3
|
KIAA0226L
|
KIAA0226-like |
| chr20_+_58296265 | 1.61 |
ENST00000395636.2
ENST00000361300.4 |
PHACTR3
|
phosphatase and actin regulator 3 |
| chr4_-_176708533 | 1.60 |
ENST00000507520.1
|
GPM6A
|
glycoprotein M6A |
| chr12_-_12837423 | 1.57 |
ENST00000540510.1
|
GPR19
|
G protein-coupled receptor 19 |
| chr15_-_56757329 | 1.56 |
ENST00000260453.3
|
MNS1
|
meiosis-specific nuclear structural 1 |
| chr12_+_25205568 | 1.54 |
ENST00000548766.1
ENST00000556887.1 |
LRMP
|
lymphoid-restricted membrane protein |
| chr10_-_15762124 | 1.53 |
ENST00000378076.3
|
ITGA8
|
integrin, alpha 8 |
| chr3_-_58613323 | 1.51 |
ENST00000474531.1
ENST00000465970.1 |
FAM107A
|
family with sequence similarity 107, member A |
| chrX_-_110039286 | 1.49 |
ENST00000434224.1
|
CHRDL1
|
chordin-like 1 |
| chr14_+_22309368 | 1.48 |
ENST00000390433.1
|
TRAV12-1
|
T cell receptor alpha variable 12-1 |
| chr15_+_51973680 | 1.47 |
ENST00000542355.2
|
SCG3
|
secretogranin III |
| chr8_+_24241789 | 1.45 |
ENST00000256412.4
ENST00000538205.1 |
ADAMDEC1
|
ADAM-like, decysin 1 |
| chr3_+_172361483 | 1.43 |
ENST00000598405.1
|
AC007919.2
|
HCG1787166; PRO1163; Uncharacterized protein |
| chr2_-_133429091 | 1.43 |
ENST00000345008.6
|
LYPD1
|
LY6/PLAUR domain containing 1 |
| chr16_+_226658 | 1.40 |
ENST00000320868.5
ENST00000397797.1 |
HBA1
|
hemoglobin, alpha 1 |
| chr11_-_114466477 | 1.33 |
ENST00000375478.3
|
NXPE4
|
neurexophilin and PC-esterase domain family, member 4 |
| chr15_+_40453204 | 1.33 |
ENST00000287598.6
ENST00000412359.3 |
BUB1B
|
BUB1 mitotic checkpoint serine/threonine kinase B |
| chrX_-_72095622 | 1.31 |
ENST00000290273.5
|
DMRTC1
|
DMRT-like family C1 |
| chr3_-_139195350 | 1.30 |
ENST00000232217.2
|
RBP2
|
retinol binding protein 2, cellular |
| chr1_+_55464600 | 1.28 |
ENST00000371265.4
|
BSND
|
Bartter syndrome, infantile, with sensorineural deafness (Barttin) |
| chr8_+_27182862 | 1.28 |
ENST00000521164.1
ENST00000346049.5 |
PTK2B
|
protein tyrosine kinase 2 beta |
| chr3_-_180397256 | 1.25 |
ENST00000442201.2
|
CCDC39
|
coiled-coil domain containing 39 |
| chr12_-_10320256 | 1.25 |
ENST00000538745.1
|
OLR1
|
oxidized low density lipoprotein (lectin-like) receptor 1 |
| chr12_+_13349650 | 1.25 |
ENST00000256951.5
ENST00000431267.2 ENST00000542474.1 ENST00000544053.1 |
EMP1
|
epithelial membrane protein 1 |
| chr2_+_207024306 | 1.19 |
ENST00000236957.5
ENST00000392221.1 ENST00000392222.2 ENST00000445505.1 |
EEF1B2
|
eukaryotic translation elongation factor 1 beta 2 |
| chr20_+_42143136 | 1.17 |
ENST00000373134.1
|
L3MBTL1
|
l(3)mbt-like 1 (Drosophila) |
| chrX_+_144908928 | 1.17 |
ENST00000408967.2
|
TMEM257
|
transmembrane protein 257 |
| chr14_-_24732368 | 1.16 |
ENST00000544573.1
|
TGM1
|
transglutaminase 1 |
| chr7_-_92855762 | 1.15 |
ENST00000453812.2
ENST00000394468.2 |
HEPACAM2
|
HEPACAM family member 2 |
| chr16_+_88872176 | 1.14 |
ENST00000569140.1
|
CDT1
|
chromatin licensing and DNA replication factor 1 |
| chr6_-_160679905 | 1.13 |
ENST00000366953.3
|
SLC22A2
|
solute carrier family 22 (organic cation transporter), member 2 |
| chr4_-_46126093 | 1.09 |
ENST00000295452.4
|
GABRG1
|
gamma-aminobutyric acid (GABA) A receptor, gamma 1 |
| chrX_-_70326455 | 1.07 |
ENST00000374251.5
|
CXorf65
|
chromosome X open reading frame 65 |
| chr12_-_11548496 | 1.06 |
ENST00000389362.4
ENST00000565533.1 ENST00000546254.1 |
PRB2
PRB1
|
proline-rich protein BstNI subfamily 2 proline-rich protein BstNI subfamily 1 |
| chr6_+_149539053 | 1.04 |
ENST00000451095.1
|
RP1-111D6.3
|
RP1-111D6.3 |
| chr12_+_25205666 | 1.04 |
ENST00000547044.1
|
LRMP
|
lymphoid-restricted membrane protein |
| chr7_-_92848878 | 1.01 |
ENST00000341723.4
|
HEPACAM2
|
HEPACAM family member 2 |
| chr4_-_123377880 | 1.01 |
ENST00000226730.4
|
IL2
|
interleukin 2 |
| chr7_-_92848858 | 1.01 |
ENST00000440868.1
|
HEPACAM2
|
HEPACAM family member 2 |
| chr7_-_766879 | 1.00 |
ENST00000537384.1
ENST00000417852.1 |
PRKAR1B
|
protein kinase, cAMP-dependent, regulatory, type I, beta |
| chr17_+_76210267 | 0.98 |
ENST00000301633.4
ENST00000350051.3 ENST00000374948.2 ENST00000590449.1 |
BIRC5
|
baculoviral IAP repeat containing 5 |
| chr12_+_13349711 | 0.97 |
ENST00000538364.1
ENST00000396301.3 |
EMP1
|
epithelial membrane protein 1 |
| chr17_-_46703826 | 0.97 |
ENST00000550387.1
ENST00000311177.5 |
HOXB9
|
homeobox B9 |
| chr6_+_34433844 | 0.96 |
ENST00000244458.2
ENST00000374043.2 |
PACSIN1
|
protein kinase C and casein kinase substrate in neurons 1 |
| chr3_+_239652 | 0.96 |
ENST00000435603.1
|
CHL1
|
cell adhesion molecule L1-like |
| chrX_-_72095808 | 0.96 |
ENST00000373529.5
|
DMRTC1
|
DMRT-like family C1 |
| chr1_+_16083098 | 0.95 |
ENST00000496928.2
ENST00000508310.1 |
FBLIM1
|
filamin binding LIM protein 1 |
| chr4_+_37245799 | 0.93 |
ENST00000309447.5
|
KIAA1239
|
KIAA1239 |
| chr6_-_132272504 | 0.93 |
ENST00000367976.3
|
CTGF
|
connective tissue growth factor |
| chr17_+_76210367 | 0.92 |
ENST00000592734.1
ENST00000587746.1 |
BIRC5
|
baculoviral IAP repeat containing 5 |
| chr6_+_84222220 | 0.92 |
ENST00000369700.3
|
PRSS35
|
protease, serine, 35 |
| chr11_-_114466471 | 0.89 |
ENST00000424261.2
|
NXPE4
|
neurexophilin and PC-esterase domain family, member 4 |
| chr3_-_87039662 | 0.86 |
ENST00000494229.1
|
VGLL3
|
vestigial like 3 (Drosophila) |
| chr3_-_121740969 | 0.86 |
ENST00000393631.1
ENST00000273691.3 ENST00000344209.5 |
ILDR1
|
immunoglobulin-like domain containing receptor 1 |
| chr22_-_50523807 | 0.85 |
ENST00000442311.1
ENST00000538737.1 |
MLC1
|
megalencephalic leukoencephalopathy with subcortical cysts 1 |
| chr6_-_131299929 | 0.83 |
ENST00000531356.1
|
EPB41L2
|
erythrocyte membrane protein band 4.1-like 2 |
| chr16_+_23194033 | 0.81 |
ENST00000300061.2
|
SCNN1G
|
sodium channel, non-voltage-gated 1, gamma subunit |
| chr7_+_30185496 | 0.80 |
ENST00000455738.1
|
C7orf41
|
maturin, neural progenitor differentiation regulator homolog (Xenopus) |
| chr14_-_24042184 | 0.79 |
ENST00000544177.1
|
JPH4
|
junctophilin 4 |
| chr14_+_22670455 | 0.78 |
ENST00000390460.1
|
TRAV26-2
|
T cell receptor alpha variable 26-2 |
| chr7_-_99716914 | 0.78 |
ENST00000431404.2
|
TAF6
|
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa |
| chr1_-_95007193 | 0.77 |
ENST00000370207.4
ENST00000334047.7 |
F3
|
coagulation factor III (thromboplastin, tissue factor) |
| chr22_-_50523760 | 0.76 |
ENST00000395876.2
|
MLC1
|
megalencephalic leukoencephalopathy with subcortical cysts 1 |
| chr4_-_119274121 | 0.75 |
ENST00000296498.3
|
PRSS12
|
protease, serine, 12 (neurotrypsin, motopsin) |
| chr17_+_61086917 | 0.75 |
ENST00000424789.2
ENST00000389520.4 |
TANC2
|
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| chr17_+_42015654 | 0.70 |
ENST00000565120.1
|
RP11-527L4.2
|
Uncharacterized protein |
| chr12_-_21810726 | 0.70 |
ENST00000396076.1
|
LDHB
|
lactate dehydrogenase B |
| chr14_+_24540154 | 0.70 |
ENST00000559778.1
ENST00000560761.1 ENST00000557889.1 |
CPNE6
|
copine VI (neuronal) |
| chr3_+_47021168 | 0.70 |
ENST00000450053.3
ENST00000292309.5 ENST00000383740.2 |
NBEAL2
|
neurobeachin-like 2 |
| chr15_+_51973708 | 0.69 |
ENST00000558709.1
|
SCG3
|
secretogranin III |
| chr6_+_52051171 | 0.69 |
ENST00000340057.1
|
IL17A
|
interleukin 17A |
| chr6_+_116782527 | 0.68 |
ENST00000368606.3
ENST00000368605.1 |
FAM26F
|
family with sequence similarity 26, member F |
| chr19_-_44259053 | 0.68 |
ENST00000601170.1
|
SMG9
|
SMG9 nonsense mediated mRNA decay factor |
| chr11_-_10715117 | 0.68 |
ENST00000527509.2
|
MRVI1
|
murine retrovirus integration site 1 homolog |
| chr20_-_17539456 | 0.67 |
ENST00000544874.1
ENST00000377868.2 |
BFSP1
|
beaded filament structural protein 1, filensin |
| chr1_+_16083123 | 0.67 |
ENST00000510393.1
ENST00000430076.1 |
FBLIM1
|
filamin binding LIM protein 1 |
| chrX_-_48776292 | 0.66 |
ENST00000376509.4
|
PIM2
|
pim-2 oncogene |
| chr17_+_73642486 | 0.66 |
ENST00000579469.1
|
SMIM6
|
small integral membrane protein 6 |
| chrX_+_115567767 | 0.65 |
ENST00000371900.4
|
SLC6A14
|
solute carrier family 6 (amino acid transporter), member 14 |
| chr14_+_24540046 | 0.64 |
ENST00000397016.2
ENST00000537691.1 ENST00000560356.1 ENST00000558450.1 |
CPNE6
|
copine VI (neuronal) |
| chr12_-_10320190 | 0.64 |
ENST00000543993.1
ENST00000339968.6 |
OLR1
|
oxidized low density lipoprotein (lectin-like) receptor 1 |
| chr20_-_44485835 | 0.64 |
ENST00000457981.1
ENST00000426915.1 ENST00000217455.4 |
ACOT8
|
acyl-CoA thioesterase 8 |
| chr19_-_44259136 | 0.64 |
ENST00000270066.6
|
SMG9
|
SMG9 nonsense mediated mRNA decay factor |
| chr17_+_76227391 | 0.64 |
ENST00000586400.1
ENST00000421688.1 ENST00000374946.3 |
TMEM235
|
transmembrane protein 235 |
| chr12_+_25205155 | 0.63 |
ENST00000550945.1
|
LRMP
|
lymphoid-restricted membrane protein |
| chr19_-_51893827 | 0.63 |
ENST00000574814.1
|
CTD-2616J11.4
|
chromosome 19 open reading frame 84 |
| chr12_-_21810765 | 0.63 |
ENST00000450584.1
ENST00000350669.1 |
LDHB
|
lactate dehydrogenase B |
| chr3_-_8811288 | 0.63 |
ENST00000316793.3
ENST00000431493.1 |
OXTR
|
oxytocin receptor |
| chr3_+_126423045 | 0.63 |
ENST00000290913.3
ENST00000508789.1 |
CHCHD6
|
coiled-coil-helix-coiled-coil-helix domain containing 6 |
| chr3_+_4535025 | 0.61 |
ENST00000302640.8
ENST00000354582.6 ENST00000423119.2 ENST00000357086.4 ENST00000456211.2 |
ITPR1
|
inositol 1,4,5-trisphosphate receptor, type 1 |
| chr1_+_228337553 | 0.61 |
ENST00000366714.2
|
GJC2
|
gap junction protein, gamma 2, 47kDa |
| chr17_+_73642315 | 0.61 |
ENST00000556126.2
|
SMIM6
|
small integral membrane protein 6 |
| chr15_+_51973550 | 0.60 |
ENST00000220478.3
|
SCG3
|
secretogranin III |
| chr4_-_819901 | 0.60 |
ENST00000304062.6
|
CPLX1
|
complexin 1 |
| chr8_+_67405794 | 0.59 |
ENST00000522977.1
ENST00000480005.1 |
C8orf46
|
chromosome 8 open reading frame 46 |
| chr8_+_67405755 | 0.59 |
ENST00000521495.1
|
C8orf46
|
chromosome 8 open reading frame 46 |
| chr12_-_75603482 | 0.58 |
ENST00000341669.3
ENST00000298972.1 ENST00000350228.2 |
KCNC2
|
potassium voltage-gated channel, Shaw-related subfamily, member 2 |
| chr16_-_66952742 | 0.58 |
ENST00000565235.2
ENST00000568632.1 ENST00000565796.1 |
CDH16
|
cadherin 16, KSP-cadherin |
| chr10_-_14596140 | 0.58 |
ENST00000496330.1
|
FAM107B
|
family with sequence similarity 107, member B |
| chr12_+_25205446 | 0.57 |
ENST00000557489.1
ENST00000354454.3 ENST00000536173.1 |
LRMP
|
lymphoid-restricted membrane protein |
| chr2_+_79252822 | 0.57 |
ENST00000272324.5
|
REG3G
|
regenerating islet-derived 3 gamma |
| chr2_+_79252834 | 0.57 |
ENST00000409471.1
|
REG3G
|
regenerating islet-derived 3 gamma |
| chr19_-_38720354 | 0.57 |
ENST00000416611.1
|
DPF1
|
D4, zinc and double PHD fingers family 1 |
| chr6_+_84222194 | 0.57 |
ENST00000536636.1
|
PRSS35
|
protease, serine, 35 |
| chr2_+_79252804 | 0.56 |
ENST00000393897.2
|
REG3G
|
regenerating islet-derived 3 gamma |
| chr22_-_50523843 | 0.56 |
ENST00000535444.1
ENST00000431262.2 |
MLC1
|
megalencephalic leukoencephalopathy with subcortical cysts 1 |
| chr5_+_140474181 | 0.55 |
ENST00000194155.4
|
PCDHB2
|
protocadherin beta 2 |
| chr13_+_108921977 | 0.54 |
ENST00000430559.1
ENST00000375887.4 |
TNFSF13B
|
tumor necrosis factor (ligand) superfamily, member 13b |
| chr11_-_67141640 | 0.54 |
ENST00000533438.1
|
CLCF1
|
cardiotrophin-like cytokine factor 1 |
| chr1_-_67266939 | 0.54 |
ENST00000304526.2
|
INSL5
|
insulin-like 5 |
| chr6_+_69942298 | 0.53 |
ENST00000238918.8
|
BAI3
|
brain-specific angiogenesis inhibitor 3 |
| chr12_-_75603202 | 0.52 |
ENST00000393288.2
|
KCNC2
|
potassium voltage-gated channel, Shaw-related subfamily, member 2 |
| chr15_+_45422178 | 0.51 |
ENST00000389037.3
ENST00000558322.1 |
DUOX1
|
dual oxidase 1 |
| chr7_+_99816859 | 0.51 |
ENST00000317271.2
|
PVRIG
|
poliovirus receptor related immunoglobulin domain containing |
| chr12_-_102591604 | 0.51 |
ENST00000329406.4
|
PMCH
|
pro-melanin-concentrating hormone |
| chr16_+_22501658 | 0.50 |
ENST00000415833.2
|
NPIPB5
|
nuclear pore complex interacting protein family, member B5 |
| chr1_-_160924589 | 0.50 |
ENST00000368029.3
|
ITLN2
|
intelectin 2 |
| chr11_-_132812987 | 0.49 |
ENST00000541867.1
|
OPCML
|
opioid binding protein/cell adhesion molecule-like |
| chr1_+_16348525 | 0.48 |
ENST00000331433.4
|
CLCNKA
|
chloride channel, voltage-sensitive Ka |
| chrX_-_110655306 | 0.48 |
ENST00000371993.2
|
DCX
|
doublecortin |
| chr11_+_35211429 | 0.48 |
ENST00000525688.1
ENST00000278385.6 ENST00000533222.1 |
CD44
|
CD44 molecule (Indian blood group) |
| chr12_-_75603643 | 0.47 |
ENST00000549446.1
|
KCNC2
|
potassium voltage-gated channel, Shaw-related subfamily, member 2 |
| chr19_-_9003586 | 0.47 |
ENST00000380951.5
|
MUC16
|
mucin 16, cell surface associated |
| chr17_-_8198636 | 0.46 |
ENST00000577745.1
ENST00000579192.1 ENST00000396278.1 |
SLC25A35
|
solute carrier family 25, member 35 |
| chr14_-_106068065 | 0.46 |
ENST00000390541.2
|
IGHE
|
immunoglobulin heavy constant epsilon |
| chr8_-_86162077 | 0.46 |
ENST00000551479.1
|
RP11-219B4.6
|
Uncharacterized protein |
| chr1_+_120839412 | 0.46 |
ENST00000355228.4
|
FAM72B
|
family with sequence similarity 72, member B |
| chr3_+_67048721 | 0.45 |
ENST00000295568.4
ENST00000484414.1 ENST00000460576.1 ENST00000417314.2 |
KBTBD8
|
kelch repeat and BTB (POZ) domain containing 8 |
| chr8_+_104310661 | 0.45 |
ENST00000522566.1
|
FZD6
|
frizzled family receptor 6 |
| chr2_-_159313214 | 0.45 |
ENST00000409889.1
ENST00000283233.5 ENST00000536771.1 |
CCDC148
|
coiled-coil domain containing 148 |
| chr3_-_150966902 | 0.45 |
ENST00000424796.2
|
P2RY14
|
purinergic receptor P2Y, G-protein coupled, 14 |
| chr15_-_70387120 | 0.45 |
ENST00000539550.1
|
TLE3
|
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) |
| chr5_+_149737202 | 0.44 |
ENST00000451292.1
ENST00000377797.3 ENST00000445265.2 ENST00000323668.7 ENST00000439160.2 ENST00000394269.3 ENST00000427724.2 ENST00000504761.2 ENST00000513346.1 ENST00000515516.1 |
TCOF1
|
Treacher Collins-Franceschetti syndrome 1 |
| chr11_+_12108410 | 0.44 |
ENST00000527997.1
|
RP13-631K18.5
|
RP13-631K18.5 |
| chr2_-_68547019 | 0.42 |
ENST00000409862.1
|
CNRIP1
|
cannabinoid receptor interacting protein 1 |
| chr1_+_158223923 | 0.41 |
ENST00000289429.5
|
CD1A
|
CD1a molecule |
| chr2_-_68547061 | 0.41 |
ENST00000263655.3
|
CNRIP1
|
cannabinoid receptor interacting protein 1 |
| chr11_-_133826852 | 0.41 |
ENST00000533871.2
ENST00000321016.8 |
IGSF9B
|
immunoglobulin superfamily, member 9B |
| chr4_+_15341442 | 0.40 |
ENST00000397700.2
ENST00000295297.4 |
C1QTNF7
|
C1q and tumor necrosis factor related protein 7 |
| chr3_+_10183447 | 0.40 |
ENST00000345392.2
|
VHL
|
von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| chr14_+_63671577 | 0.40 |
ENST00000555125.1
|
RHOJ
|
ras homolog family member J |
| chr15_-_35047166 | 0.40 |
ENST00000290374.4
|
GJD2
|
gap junction protein, delta 2, 36kDa |
| chr7_-_38295997 | 0.40 |
ENST00000390334.1
|
TRGJP2
|
T cell receptor gamma joining P2 |
| chr6_+_149539106 | 0.40 |
ENST00000443992.1
|
RP1-111D6.3
|
RP1-111D6.3 |
| chr6_+_43968306 | 0.40 |
ENST00000442114.2
ENST00000336600.5 ENST00000439969.2 |
C6orf223
|
chromosome 6 open reading frame 223 |
| chr3_-_53290016 | 0.39 |
ENST00000423525.2
ENST00000423516.1 ENST00000296289.6 ENST00000462138.1 |
TKT
|
transketolase |
| chr4_-_164253738 | 0.38 |
ENST00000509586.1
ENST00000504391.1 ENST00000512819.1 |
NPY1R
|
neuropeptide Y receptor Y1 |
| chr8_+_128426535 | 0.38 |
ENST00000465342.2
|
POU5F1B
|
POU class 5 homeobox 1B |
| chrX_+_591524 | 0.38 |
ENST00000554971.1
ENST00000381575.1 |
SHOX
|
short stature homeobox |
| chr16_-_55478666 | 0.37 |
ENST00000565307.1
|
RP11-212I21.2
|
RP11-212I21.2 |
| chr12_+_25205628 | 0.37 |
ENST00000554942.1
|
LRMP
|
lymphoid-restricted membrane protein |
| chr15_-_77363441 | 0.36 |
ENST00000346495.2
ENST00000424443.3 ENST00000561277.1 |
TSPAN3
|
tetraspanin 3 |
| chr17_-_62502399 | 0.35 |
ENST00000450599.2
ENST00000585060.1 |
DDX5
|
DEAD (Asp-Glu-Ala-Asp) box helicase 5 |
| chr12_-_49504449 | 0.34 |
ENST00000547675.1
|
LMBR1L
|
limb development membrane protein 1-like |
| chr17_-_28661065 | 0.34 |
ENST00000328886.4
ENST00000538566.2 |
TMIGD1
|
transmembrane and immunoglobulin domain containing 1 |
| chr13_-_46756351 | 0.33 |
ENST00000323076.2
|
LCP1
|
lymphocyte cytosolic protein 1 (L-plastin) |
| chr7_-_36764142 | 0.33 |
ENST00000258749.5
ENST00000535891.1 |
AOAH
|
acyloxyacyl hydrolase (neutrophil) |
| chr18_+_44497455 | 0.33 |
ENST00000592005.1
|
KATNAL2
|
katanin p60 subunit A-like 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of NKX2-8
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.2 | GO:0016999 | antibiotic metabolic process(GO:0016999) |
| 0.6 | 1.7 | GO:0044278 | cell wall disruption in other organism(GO:0044278) |
| 0.5 | 1.6 | GO:0034059 | response to anoxia(GO:0034059) |
| 0.4 | 35.4 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.4 | 1.7 | GO:0072086 | specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268) |
| 0.4 | 2.8 | GO:0043163 | cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229) |
| 0.4 | 1.1 | GO:1902595 | regulation of DNA replication origin binding(GO:1902595) |
| 0.3 | 1.3 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
| 0.3 | 1.5 | GO:2000721 | positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721) |
| 0.3 | 1.5 | GO:0048749 | compound eye development(GO:0048749) |
| 0.3 | 2.8 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 0.3 | 0.8 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.3 | 1.0 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.2 | 29.3 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.2 | 1.7 | GO:0038060 | nitric oxide-cGMP-mediated signaling pathway(GO:0038060) |
| 0.2 | 1.9 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 0.2 | 1.3 | GO:2000537 | regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 0.1 | 0.7 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296) |
| 0.1 | 1.3 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.1 | 0.7 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 0.1 | 2.2 | GO:0001865 | NK T cell differentiation(GO:0001865) |
| 0.1 | 0.5 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 0.1 | 1.7 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 0.1 | 1.8 | GO:0002517 | T cell tolerance induction(GO:0002517) |
| 0.1 | 0.6 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.1 | 0.4 | GO:0005997 | xylulose metabolic process(GO:0005997) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 0.1 | 0.5 | GO:0042335 | cuticle development(GO:0042335) |
| 0.1 | 0.3 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
| 0.1 | 2.2 | GO:0071397 | cellular response to cholesterol(GO:0071397) |
| 0.1 | 1.1 | GO:1901374 | acetate ester transport(GO:1901374) |
| 0.1 | 0.4 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 0.1 | 1.6 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.1 | 1.3 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.1 | 1.9 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
| 0.1 | 0.2 | GO:0001694 | histamine biosynthetic process(GO:0001694) |
| 0.1 | 2.2 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.1 | 1.8 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 1.6 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.1 | 0.5 | GO:0048295 | positive regulation of isotype switching to IgE isotypes(GO:0048295) |
| 0.1 | 0.2 | GO:2001226 | negative regulation of chloride transport(GO:2001226) |
| 0.1 | 0.2 | GO:0048789 | cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942) |
| 0.1 | 1.4 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.1 | 0.5 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.1 | 0.9 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.1 | 0.2 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
| 0.1 | 0.3 | GO:0043324 | eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) |
| 0.0 | 0.1 | GO:0038193 | thromboxane A2 signaling pathway(GO:0038193) |
| 0.0 | 0.1 | GO:0032203 | telomere formation via telomerase(GO:0032203) |
| 0.0 | 1.0 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 1.4 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.0 | 1.0 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 0.0 | 0.4 | GO:0048007 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.0 | 0.7 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.0 | 0.3 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.0 | 0.1 | GO:0002476 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) |
| 0.0 | 0.5 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.0 | 0.3 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.0 | 0.1 | GO:1901877 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 0.0 | 1.4 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 1.0 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.0 | 0.8 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.0 | 0.6 | GO:0016559 | peroxisome fission(GO:0016559) |
| 0.0 | 0.4 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
| 0.0 | 0.2 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.0 | 0.1 | GO:0018874 | benzoate metabolic process(GO:0018874) |
| 0.0 | 1.8 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.0 | 1.6 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.0 | 1.3 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.4 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.0 | 4.0 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.0 | 1.1 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.4 | GO:0019614 | catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424) |
| 0.0 | 3.2 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.0 | 0.7 | GO:0030220 | platelet formation(GO:0030220) |
| 0.0 | 2.4 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 0.3 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.0 | 0.2 | GO:0010663 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 0.0 | 0.5 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.3 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.0 | 3.2 | GO:0007098 | centrosome cycle(GO:0007098) |
| 0.0 | 0.1 | GO:0006848 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.0 | 1.0 | GO:0031103 | axon regeneration(GO:0031103) |
| 0.0 | 0.2 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.0 | 0.3 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.0 | 0.2 | GO:0007625 | grooming behavior(GO:0007625) |
| 0.0 | 0.6 | GO:0010644 | cell communication by electrical coupling(GO:0010644) |
| 0.0 | 0.8 | GO:0055078 | sodium ion homeostasis(GO:0055078) |
| 0.0 | 0.3 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.0 | 0.2 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.0 | 0.0 | GO:0030578 | PML body organization(GO:0030578) |
| 0.0 | 0.0 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 35.4 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.4 | 1.4 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.3 | 1.5 | GO:0034678 | integrin alpha8-beta1 complex(GO:0034678) |
| 0.2 | 1.9 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.2 | 4.0 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 0.5 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059) |
| 0.1 | 1.3 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.1 | 1.3 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
| 0.1 | 0.6 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.1 | 0.6 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.1 | 0.9 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.1 | 0.6 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.1 | 0.8 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.1 | 2.2 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 1.5 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 0.4 | GO:0030891 | VCB complex(GO:0030891) |
| 0.0 | 0.8 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.0 | 0.2 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
| 0.0 | 0.3 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.0 | 0.8 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 1.6 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 1.0 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 1.0 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 1.7 | GO:0032809 | axolemma(GO:0030673) neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.0 | 0.8 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.0 | 3.2 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 0.8 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.0 | 1.0 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.0 | 0.7 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.0 | 0.8 | GO:0034706 | sodium channel complex(GO:0034706) |
| 0.0 | 1.7 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 2.6 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 0.3 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.0 | 0.4 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 0.6 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.0 | 1.8 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.1 | GO:0042825 | TAP complex(GO:0042825) |
| 0.0 | 0.2 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.0 | 0.1 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.0 | 1.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 2.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.8 | GO:0097517 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.3 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.0 | 2.1 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 0.3 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.0 | 0.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 3.6 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 1.0 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 3.7 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 3.2 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 1.6 | GO:0016234 | inclusion body(GO:0016234) |
| 0.0 | 1.9 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 1.3 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 2.2 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 2.8 | GO:0031751 | D4 dopamine receptor binding(GO:0031751) |
| 0.5 | 35.4 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.4 | 1.7 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
| 0.4 | 1.2 | GO:0032093 | SAM domain binding(GO:0032093) |
| 0.4 | 1.4 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.3 | 0.9 | GO:0070506 | high-density lipoprotein particle receptor activity(GO:0070506) |
| 0.3 | 1.1 | GO:0005277 | acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375) |
| 0.2 | 4.0 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.2 | 1.3 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.2 | 2.2 | GO:0034235 | GPI anchor binding(GO:0034235) metallodipeptidase activity(GO:0070573) |
| 0.2 | 2.8 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.2 | 1.7 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.2 | 0.6 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.1 | 29.8 | GO:0003823 | antigen binding(GO:0003823) |
| 0.1 | 2.0 | GO:1903136 | cuprous ion binding(GO:1903136) |
| 0.1 | 0.6 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.1 | 1.0 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208) |
| 0.1 | 0.4 | GO:0004802 | transketolase activity(GO:0004802) |
| 0.1 | 1.0 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.1 | 0.4 | GO:0001601 | peptide YY receptor activity(GO:0001601) |
| 0.1 | 1.7 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.1 | 0.3 | GO:0035643 | L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544) |
| 0.1 | 0.8 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.1 | 1.4 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.1 | 0.6 | GO:1903763 | gap junction channel activity involved in cell communication by electrical coupling(GO:1903763) |
| 0.1 | 1.8 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 0.7 | GO:0015065 | uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553) |
| 0.1 | 0.5 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.1 | 0.1 | GO:0046978 | peptide antigen-transporting ATPase activity(GO:0015433) TAP binding(GO:0046977) TAP1 binding(GO:0046978) |
| 0.1 | 1.6 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 1.7 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.4 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
| 0.0 | 0.1 | GO:0004960 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
| 0.0 | 1.9 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.0 | 0.6 | GO:0005000 | vasopressin receptor activity(GO:0005000) |
| 0.0 | 0.8 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.0 | 0.3 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.0 | 0.3 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.0 | 1.0 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.0 | 0.2 | GO:0050528 | acyloxyacyl hydrolase activity(GO:0050528) |
| 0.0 | 0.8 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.0 | 0.4 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.0 | 1.6 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 1.0 | GO:0019841 | retinol binding(GO:0019841) |
| 0.0 | 0.4 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 1.3 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.2 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.0 | 1.1 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 1.2 | GO:0005326 | neurotransmitter transporter activity(GO:0005326) |
| 0.0 | 0.5 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.0 | 0.3 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.0 | 1.9 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.1 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.0 | 0.3 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.0 | 0.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.9 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 0.2 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 0.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 2.0 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.3 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.0 | 1.3 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 1.9 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
| 0.0 | 0.2 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.0 | 0.1 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.0 | 0.3 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 1.7 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 1.5 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.0 | 1.9 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.3 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 2.7 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 0.3 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.0 | 0.9 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 1.5 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 0.8 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.9 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 0.9 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 1.3 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 3.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 1.1 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 0.1 | 1.7 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.1 | 3.8 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.6 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 1.9 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 1.0 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 0.6 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.0 | 1.3 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 0.0 | 2.2 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 2.3 | REACTOME IL 2 SIGNALING | Genes involved in Interleukin-2 signaling |
| 0.0 | 1.5 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 1.0 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 0.7 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.0 | 1.7 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.0 | 0.7 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 1.2 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 0.3 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.0 | 0.9 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 2.4 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 0.8 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.8 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.0 | 0.4 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 1.7 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.0 | 0.4 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.9 | REACTOME COSTIMULATION BY THE CD28 FAMILY | Genes involved in Costimulation by the CD28 family |
| 0.0 | 0.1 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 1.5 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 1.3 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.0 | 0.8 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 0.5 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |